Publications by authors named "Haoqiang Ying"

62Publications

Enhancer Reprogramming Confers Dependence on Glycolysis and IGF Signaling in KMT2D Mutant Melanoma.

Cell Rep 2020 Oct;33(3):108293

Department of Genomic Medicine, University of Texas MD Anderson Cancer Center, Houston, TX, USA; Graduate Program in Quantitative Sciences, Baylor College of Medicine, Houston, TX, USA; Graduate School of Biomedical Sciences, University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2020.108293DOI Listing
October 2020

The stabilization of PD-L1 by the endoplasmic reticulum stress protein GRP78 in triple-negative breast cancer.

Am J Cancer Res 2020 1;10(8):2621-2634. Epub 2020 Aug 1.

Graduate Institute of Biomedical Sciences, China Medical University Taichung 404, Taiwan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471351PMC
August 2020

Recent insights into the biology of pancreatic cancer.

EBioMedicine 2020 Mar 2;53:102655. Epub 2020 Mar 2.

Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2020.102655DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118569PMC
March 2020

Mst1/2 kinases restrain transformation in a novel transgenic model of Ras driven non-small cell lung cancer.

Oncogene 2020 Jan 30;39(5):1152-1164. Epub 2019 Sep 30.

Division of Gastroenterology, Hepatology and Nutrition, Department of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.

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http://dx.doi.org/10.1038/s41388-019-1031-zDOI Listing
January 2020

Glucose Metabolism in Pancreatic Cancer.

Cancers (Basel) 2019 Sep 29;11(10). Epub 2019 Sep 29.

Department of Molecular and Cellular Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.3390/cancers11101460DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826406PMC
September 2019

Oncogenic KRAS supports pancreatic cancer through regulation of nucleotide synthesis.

Nat Commun 2018 11 23;9(1):4945. Epub 2018 Nov 23.

Division of Genomic Stability and DNA Repair, Department of Radiation Oncology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.

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http://dx.doi.org/10.1038/s41467-018-07472-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251888PMC
November 2018

Angiogenin/Ribonuclease 5 Is an EGFR Ligand and a Serum Biomarker for Erlotinib Sensitivity in Pancreatic Cancer.

Cancer Cell 2018 04 29;33(4):752-769.e8. Epub 2018 Mar 29.

Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Unit 108, 1515 Holcombe Boulevard, Houston, TX 77030, USA; Graduate School of Biomedical Sciences, The University of Texas Health Science Center, Houston, TX 77030, USA; Graduate Institute of Biomedical Sciences and Center for Molecular Medicine, China Medical University, Taichung 404, Taiwan; Department of Biotechnology, Asia University, Taichung 413, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2018.02.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893359PMC
April 2018

A tumor vessel-targeting fusion protein elicits a chemotherapeutic bystander effect in pancreatic ductal adenocarcinoma.

Am J Cancer Res 2017 1;7(3):657-672. Epub 2017 Mar 1.

Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer CenterHouston, Texas 77030, USA; Graduate School of Biomedical Sciences, The University of Texas Houston Health Science CenterHouston, Texas 77030, USA; Center for Molecular Medicine and Graduate Institute of Cancer Biology, China Medical UniversityTaichung 404, Taiwan; Department of Biotechnology, Asia UniversityTaichung 413, Taiwan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385650PMC
March 2017

KRAS-related proteins in pancreatic cancer.

Pharmacol Ther 2016 12 3;168:29-42. Epub 2016 Sep 3.

Cancer Research Program, Houston Methodist Research Institute, Houston, TX 77030, USA.

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http://dx.doi.org/10.1016/j.pharmthera.2016.09.003DOI Listing
December 2016

Inhibition of Cdc42 is essential for Mig-6 suppression of cell migration induced by EGF.

Oncotarget 2016 Aug;7(31):49180-49193

Center of Growth, Metabolism and Aging, Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, 610014, China.

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http://dx.doi.org/10.18632/oncotarget.10205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226500PMC
August 2016

Genetics and biology of pancreatic ductal adenocarcinoma.

Genes Dev 2016 Feb;30(4):355-85

Department of Cancer Biology, University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA;

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http://genesdev.cshlp.org/lookup/doi/10.1101/gad.275776.115
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http://dx.doi.org/10.1101/gad.275776.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762423PMC
February 2016

Genetic events that limit the efficacy of MEK and RTK inhibitor therapies in a mouse model of KRAS-driven pancreatic cancer.

Cancer Res 2015 Mar 3;75(6):1091-101. Epub 2015 Mar 3.

Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas. Institute for Applied Cancer Science, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-1854DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446709PMC
March 2015

Cancer signaling: when phosphorylation meets methylation.

Cell Res 2014 Nov 8;24(11):1282-3. Epub 2014 Aug 8.

Departments of Cancer Biology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1038/cr.2014.103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220151PMC
November 2014

Neuroplastic changes occur early in the development of pancreatic ductal adenocarcinoma.

Cancer Res 2014 Mar 21;74(6):1718-27. Epub 2014 Jan 21.

Authors' Affiliations: Departments of Neurobiology, Biostatistics, Pathology, and Medicine, University of Pittsburgh School of Medicine; Departments of Genomic Medicine and Cancer Biology, University of Texas MD Anderson Cancer Center, Houston, Texas; and Department of Internal Medicine, University of Michigan School of Medicine, Ann Arbor, Michigan.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-2050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036226PMC
March 2014

FoxO3 coordinates metabolic pathways to maintain redox balance in neural stem cells.

EMBO J 2013 Oct 6;32(19):2589-602. Epub 2013 Sep 6.

Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York City, NY, USA.

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http://dx.doi.org/10.1038/emboj.2013.186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791369PMC
October 2013

ZNF365 promotes stability of fragile sites and telomeres.

Cancer Discov 2013 Jul 17;3(7):798-811. Epub 2013 Jun 17.

Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, USA.

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http://dx.doi.org/10.1158/2159-8290.CD-12-0536DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710545PMC
July 2013

Rapamycin inhibits IGF-1-mediated up-regulation of MDM2 and sensitizes cancer cells to chemotherapy.

PLoS One 2013 30;8(4):e63179. Epub 2013 Apr 30.

Department of Biochemistry, Boston University School of Medicine, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0063179PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640086PMC
November 2013

Action of db-cAMP on the bystander effect and chemosensitivity through connexin 43 and Bcl-2-mediated pathways in medulloblastoma cells.

Oncol Rep 2012 Sep 5;28(3):969-76. Epub 2012 Jul 5.

Department of Neurosurgery, Shengjing Hospital of China Medical University, Shenyang 110004, PR China.

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http://dx.doi.org/10.3892/or.2012.1900DOI Listing
September 2012

Pancreatic cancers require autophagy for tumor growth.

Genes Dev 2011 Apr 15;25(7):717-29. Epub 2011 Mar 15.

Division of Genomic Stability and DNA Repair, Department of Radiation Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1101/gad.2016111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070934PMC
April 2011

Increasing of blood-tumor barrier permeability through paracellular pathway by low-frequency ultrasound irradiation in vitro.

J Mol Neurosci 2011 Mar 23;43(3):541-8. Epub 2010 Nov 23.

Department of Neurosurgery, Shengjing Hospital of China Medical University, Shenyang, 110004, People's Republic of China.

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http://link.springer.com/content/pdf/10.1007/s12031-010-9479
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http://link.springer.com/10.1007/s12031-010-9479-x
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http://dx.doi.org/10.1007/s12031-010-9479-xDOI Listing
March 2011

Inhibition of RelB by 1,25-dihydroxyvitamin D3 promotes sensitivity of breast cancer cells to radiation.

J Cell Physiol 2009 Sep;220(3):593-9

Department of Biochemistry, Boston University School of Medicine, Boston, Massachusetts 02118, USA.

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http://dx.doi.org/10.1002/jcp.21765DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900382PMC
September 2009

Targeting retinoblastoma protein for degradation by proteasomes.

Cell Cycle 2006 Mar 1;5(5):506-8. Epub 2006 Mar 1.

Department of Biochemistry, Boston University School of Medicine, Boston, Massachusetts 02118, USA.

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http://dx.doi.org/10.4161/cc.5.5.2515DOI Listing
March 2006

MDM2 promotes proteasome-dependent ubiquitin-independent degradation of retinoblastoma protein.

Mol Cell 2005 Dec;20(5):699-708

Department of Biochemistry, Boston University School of Medicine, Massachusetts 02118, USA.

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http://dx.doi.org/10.1016/j.molcel.2005.10.017DOI Listing
December 2005

DNA-binding and transactivation activities are essential for TAp63 protein degradation.

Mol Cell Biol 2005 Jul;25(14):6154-64

Department of Biochemistry, Boston University School of Medicine, K423, 715 Albany St., Boston, Massachusetts 02118, USA.

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http://dx.doi.org/10.1128/MCB.25.14.6154-6164.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1168832PMC
July 2005

Increased expression of MDM2, cyclin D1, and p27Kip1 in carcinogen-induced rat mammary tumors.

J Cell Biochem 2005 Aug;95(5):875-84

Department of Biochemistry, Boston University School of Medicine, Boston, Massachusetts 02118, USA.

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http://dx.doi.org/10.1002/jcb.20414DOI Listing
August 2005

The central acidic domain of MDM2 is critical in inhibition of retinoblastoma-mediated suppression of E2F and cell growth.

J Biol Chem 2004 Dec 13;279(51):53317-22. Epub 2004 Oct 13.

Department of Biochemistry, Boston University School of Medicine, Boston, MA 02118, USA.

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http://dx.doi.org/10.1074/jbc.M406062200DOI Listing
December 2004

The MDM2 RING finger is required for cell cycle-dependent regulation of its protein expression.

FEBS Lett 2003 Jun;544(1-3):218-22

Department of Biochemistry, Boston University School of Medicine, 715 Albany Street, K423, MA 02118, USA.

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http://dx.doi.org/10.1016/s0014-5793(03)00502-7DOI Listing
June 2003

Deregulation of Cdc2 kinase induces caspase-3 activation and apoptosis.

Biochem Biophys Res Commun 2003 Mar;302(2):384-91

Department of Biochemistry, Boston University School of Medicine, Boston, MA 02118, USA.

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http://dx.doi.org/10.1016/s0006-291x(03)00189-xDOI Listing
March 2003