Hany Aref - Ain Shams University

Hany Aref

Ain Shams University

Cairo | Egypt

Main Specialties: Neurology

Additional Specialties: Neurology

ORCID logohttps://orcid.org/0000-0003-1497-7915

Hany Aref - Ain Shams University

Hany Aref

Introduction

Primary Affiliation: Ain Shams University - Cairo , Egypt

Specialties:

Additional Specialties:

Research Interests:

Education

Oct 1978
Ain Shams University Faculty of Medicine
MD, FAAN
neurology

Experience

Aug 1988
Ain Shams University Faculty of Medicine

neurology

Publications

12Publications

81Reads

1206Profile Views

8PubMed Central Citations

Vitamin D and body mass index in Egyptian multiple sclerosis patients.

Mult Scler Relat Disord 2019 Feb 1;28:313-316. Epub 2018 Dec 1.

Neurology Department, Ain Shams University Cairo, Cairo, Egypt. Electronic address:

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http://dx.doi.org/10.1016/j.msard.2018.11.035DOI Listing
February 2019

Clinical Characteristics of Borderzone Infarction in Egyptian Population.

J Stroke Cerebrovasc Dis 2019 Jan 16. Epub 2019 Jan 16.

Department of Neurology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2019.01.003DOI Listing
January 2019
1.993 Impact Factor

Clinical Characteristics of Borderzone Infarction in Egyptian Population

journal of stroke and cerebrovascular diseases

Objectives: In this research we wanted to highlight the importance of defining Borderzone infarctions (BZI) as a separate subtype in stroke classifications. We thus studied cases of isolated BZI, small vessel disease (SVD), and large vessel disease (LVD), to identify their points of similarities and difference in a sample of Egyptian patients. Methods: This is a cross-sectional (observational) study. Consecutive 637 acute ischemic stroke patients were recruited over a 2 year period, from 2 stroke units of Ain Shams University hospitals in Egypt. Medical history and laboratory investigations were done to identify risk factors. National Institute of Health Stroke Scale (NIHSS) was performed on admission, and modified Rankin scale (mRS) on admission, and after 3 months. MRI brain was done to identify stroke subtype; MRA and carotid duplex were used to define vascular status. Results: Among the studied group of patients, 72 (11.3%) had BZI, 145 (22.8%) had SVD, 165 (26%) had LVD, and 255 were excluded as they had either undetermined, or mixed etiology. BZI showed significantly older age, early confluent lesions, more disease severity by NIHSS, and worst outcome by mRS (P < 0.05). SVD had more microbleeds than BZI and LVD. LVD showed lower prevalence of hypertension and lower high-density lipoprotein levels. Conclusions: Isolated BZI, SVD, and LVD infarctions have characteristic risk factors and clinical patterns. Further studies are needed to identify if they are different from cases with mixed pathology. This could have an impact on the selection of primary and secondary preventive measures appropriate to each type.

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January 2019
1 Read

Vitamin D and Body Mass Index in Egyptian Multiple Sclerosis Patients

Multiple Sclerosis and Related Disorders


Background: Vitamin D deficiency and obesity may be related to the pathogenesis and disease activity of multiple sclerosis (MS). This study aimed to assess the correlation between the serum level of 25(OH) vitamin D, body mass index (BMI) and the Expanded Disability Status Scale (EDSS) in a sample of Egyptian MS patients. Subjects and Methods: This was an observational study that included 130 MS patients who were recruited consecutively among the patients attending the MS unit of Ain Shams University Hospital, Cairo, in the period between December 2017 and March 2018. The serum level of 25(OH) D, BMI and EDSS were recorded. Results: : Females represented 77.7% of the study sample, the mean age was 32.4 ± 8.2 years. MS types were: RRMS 83.1%, SPMS 14.6% and PPMS in 2.3%. Serum level of 25(OH) vitamin D was deficient (less than 10 ng/ml) in 69.2% and insufficient (10–30 ng/ml) in 19.2% of the study population. The mean BMI was 25.5 ± 4.7 kg/m² (classified as overweight). The mean EDSS was 3.5 ± 1.9. The relationship between the EDSS score and 25(OH) D level was inversely correlated, all patients with EDSS ≤ 2 had sufficient levels while all patients with EDSS ≥ 4.5 had deficient levels. High EDSS scores were statistically correlated (p < 0.001) to high BMI and low Log 25(OH) D levels. An inverse correlation was found between the BMI and log 25(OH) D. Conclusion: Vitamin D deficiency and overweight are predominant among Egyptian MS patients. The EDSS was positively correlated to the BMI and negatively correlated to 25(OH) D. These factors may possibly play a role in the pathogeneses and progression of MS in Egypt.

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December 2018
1 Read

Egyptian experience in increasing utilization of reperfusion therapies in acute ischemic stroke.

Int J Stroke 2018 07 6;13(5):525-529. Epub 2017 Jun 6.

Department of Neurology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

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http://dx.doi.org/10.1177/1747493017711949DOI Listing
July 2018
24 Reads
3.833 Impact Factor

Clinical characteristics of patients with multiple sclerosis enrolled in a new registry in Egypt.

Mult Scler Relat Disord 2016 Nov 27;10:30-35. Epub 2016 Jun 27.

Department of Community Medicine, Ain Shams University, Cairo, Egypt.

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http://dx.doi.org/10.1016/j.msard.2016.06.013DOI Listing
November 2016
6 Reads
2 Citations

ACE Gene in Egyptian Ischemic Stroke Patients.

J Stroke Cerebrovasc Dis 2016 Sep 25;25(9):2167-71. Epub 2016 Jul 25.

Neuropsychiatry Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2015.05.015DOI Listing
September 2016
5 Reads
1.993 Impact Factor

Real-world evaluation of compliance and preference in Alzheimer's disease treatment.

Clin Interv Aging 2015 3;10:1779-87. Epub 2015 Nov 3.

Novartis Pharma AG, Postfach, Basel, Switzerland.

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http://dx.doi.org/10.2147/CIA.S85319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4639476PMC
July 2016
13 Reads
1 Citation
1.824 Impact Factor

Elevated serum Bcl-2 in children with temporal lobe epilepsy.

Seizure 2012 May 23;21(4):250-3. Epub 2012 Feb 23.

Department of Research on Children with Special Needs, National Research Center, Egypt.

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http://dx.doi.org/10.1016/j.seizure.2012.01.004DOI Listing
May 2012
7 Reads
1 Citation
2.060 Impact Factor

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