Publications by authors named "Hans-Guenter Zerwes"

7 Publications

  • Page 1 of 1

Requirement of Mucosa-Associated Lymphoid Tissue Lymphoma Translocation Protein 1 Protease Activity for Fcγ Receptor-Induced Arthritis, but Not Fcγ Receptor-Mediated Platelet Elimination, in Mice.

Authors:
Kea Martin Ratiba Touil Grozdan Cvijetic Laura Israel Yeter Kolb Sophie Sarret Stéphanie Valeaux Elena Degl'Innocenti Thomas Le Meur Nadja Caesar Maureen Bardet Christian Beerli Hans-Guenter Zerwes Jiri Kovarik Karen Beltz Achim Schlapbach Jean Quancard Catherine H Régnier Marc Bigaud Tobias Junt Grazyna Wieczorek Isabelle Isnardi Amanda Littlewood-Evans Frédéric Bornancin Thomas Calzascia

Arthritis Rheumatol 2020 06 26;72(6):919-930. Epub 2020 Apr 26.

Novartis Institutes for BioMedical Research, Basel, Switzerland.

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June 2020

Special ergolines efficiently inhibit the chemokine receptor CXCR3 in blood.

Authors:
Gebhard Thoma Rolf Baenteli Ian Lewis Darryl Jones Jiri Kovarik Markus B Streiff Hans-Guenter Zerwes

Bioorg Med Chem Lett 2011 Aug 29;21(16):4745-9. Epub 2011 Jun 29.

Novartis Institutes for BioMedical Research, Forum 1, Novartis Campus, Lichtstrasse 35, CH-4056 Basel, Switzerland.

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August 2011

Targeting the CXCR4-CXCL12 axis mobilizes autologous hematopoietic stem cells and prolongs islet allograft survival via programmed death ligand 1.

Authors:
Paolo Fiorina Mollie Jurewicz Andrea Vergani Alessandra Petrelli Michele Carvello Francesca D'Addio Jonathan G Godwin Kenneth Law Erxi Wu Ze Tian Gebhard Thoma Jiri Kovarik Stefano La Rosa Carlo Capella Scott Rodig Hans-Guenter Zerwes Mohamed H Sayegh Reza Abdi

J Immunol 2011 Jan 3;186(1):121-31. Epub 2010 Dec 3.

Transplantation Research Center, Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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January 2011

Special ergolines are highly selective, potent antagonists of the chemokine receptor CXCR3: discovery, characterization and preliminary SAR of a promising lead.

Authors:
Gebhard Thoma Rolf Baenteli Ian Lewis Trixie Wagner Lukas Oberer Wolfgang Blum Fraser Glickman Markus B Streiff Hans-Guenter Zerwes

Bioorg Med Chem Lett 2009 Nov 6;19(21):6185-8. Epub 2009 Sep 6.

Novartis Institutes for BioMedical Research, Forum 1, Novartis Campus, CH-4056 Basel, Switzerland.

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November 2009

Reduced cardiac side-effect potential by introduction of polar groups: discovery of NIBR-1282, an orally bioavailable CCR5 antagonist which is active in vivo.

Authors:
Gebhard Thoma Christian Beerli Marc Bigaud Christian Bruns Nigel G Cooke Markus B Streiff Hans-Guenter Zerwes

Bioorg Med Chem Lett 2008 Mar 2;18(6):2000-5. Epub 2008 Feb 2.

Novartis Institutes for BioMedical Research, Forum 1, Novartis Campus, CH-4002 Basel, Switzerland.

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March 2008

Orally bioavailable competitive CCR5 antagonists.

Authors:
Gebhard Thoma François Nuninger Marc Schaefer Kayhan G Akyel Rainer Albert Christian Beerli Christian Bruns Eric Francotte Marcel Luyten Duncan MacKenzie Lukas Oberer Markus B Streiff Trixie Wagner Hansrudolf Walter Gisbert Weckbecker Hans-Guenter Zerwes

J Med Chem 2004 Apr;47(8):1939-55

Novartis Institutes for BioMedical Research, Lichtstrasse 35, WSJ-507.4.12, CH-4056 Basel, Switzerland.

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April 2004

Interferon-gamma plays a nonredundant role in mediating T cell-dependent outward vascular remodeling of allogeneic human coronary arteries.

Authors:
Yinong Wang William R Burns Paul C Y Tang Tai Yi Jeffrey S Schechner Hans-Guenter Zerwes William C Sessa Marc I Lorber Jordan S Pober George Tellides

FASEB J 2004 Mar 20;18(3):606-8. Epub 2004 Jan 20.

Interdepartmental Program in Vascular Biology and Transplantation, and the Department of Surgery, Yale University School of Medicine, New Haven, Connecticut 06510, USA.

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March 2004