Hans-Dieter Klenk

Hans-Dieter Klenk

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Hans-Dieter Klenk

Hans-Dieter Klenk

Publications by authors named "Hans-Dieter Klenk"

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New filovirus disease classification and nomenclature.

Nat Rev Microbiol 2019 May;17(5):261-263

World Health Organization Regional Office for Africa, Brazzaville, Democratic Republic of the Congo.

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http://dx.doi.org/10.1038/s41579-019-0187-4DOI Listing
May 2019

Double Lock of a Human Neutralizing and Protective Monoclonal Antibody Targeting the Yellow Fever Virus Envelope.

Cell Rep 2019 Jan;26(2):438-446.e5

Laboratory of Protein Engineering and Vaccines, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300308, China; CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China; Research Network of Immunity and Health (RNIH), Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing 100101, China; National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247183201
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http://dx.doi.org/10.1016/j.celrep.2018.12.065DOI Listing
January 2019

Marburg- and Ebolaviruses: A Look Back and Lessons for the Future.

Methods Mol Biol 2017 ;1628:3-14

Institut für Virologie, Philipps-Universität Marburg, Marburg, Germany.

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http://dx.doi.org/10.1007/978-1-4939-7116-9_1DOI Listing
March 2018

Acetylcholine Receptor Antibody Titers and Clinical Course after Influenza Vaccination in Patients with Myasthenia Gravis: A Double-Blind Randomized Controlled Trial (ProPATIent-Trial).

EBioMedicine 2018 Feb 10;28:143-150. Epub 2018 Jan 10.

Klinik für Neurologie, Philipps-Universität und Universitätsklinikum Marburg, Baldingerstr. 1, Marburg 35043, Germany; Klinik für Neurologie, Klinikum Christophsbad, Faurndauer Str. 6, Göppingen 73035, Germany.

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http://dx.doi.org/10.1016/j.ebiom.2018.01.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835557PMC
February 2018

H7N9 Influenza A Virus Exhibits Importin-α7-Mediated Replication in the Mammalian Respiratory Tract.

Am J Pathol 2017 Apr 9;187(4):831-840. Epub 2017 Feb 9.

Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg, Germany; Center for Structural and Cellular Biology in Medicine, University of Lübeck, Lübeck, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2016.12.017DOI Listing
April 2017

Adaptive mutation PB2 D701N promotes nuclear import of influenza vRNPs in mammalian cells.

Eur J Cell Biol 2015 Jul-Sep;94(7-9):368-74. Epub 2015 Jun 2.

Institute of Virology, Philipps Universität, Marburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejcb.2015.05.012DOI Listing
June 2016

PB2 subunit of avian influenza virus subtype H9N2: a pandemic risk factor.

J Gen Virol 2016 Jan 11;97(1):39-48. Epub 2015 Nov 11.

1​Institute of Virology, Philipps University, Hans-Meerwein-Straße 2, 35043 Marburg, Germany.

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http://dx.doi.org/10.1099/jgv.0.000333DOI Listing
January 2016

Sialic Acid Receptors of Viruses.

Top Curr Chem 2015 ;367:1-28

Institut für Virologie, Philipps-Universität, Hans-Meerwein-Str. 2, 35043, Marburg, Germany.

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http://dx.doi.org/10.1007/128_2013_466DOI Listing
November 2015

Shedding of Ebola Virus Surface Glycoprotein Is a Mechanism of Self-regulation of Cellular Cytotoxicity and Has a Direct Effect on Virus Infectivity.

J Infect Dis 2015 Oct 19;212 Suppl 2:S322-8. Epub 2015 Jun 19.

Molecular Basis of Viral Pathogenicity, CIRI, INSERM U1111 - CNRS UMR5308, Université de Lyon, Université Claude Bernard Lyon 1, Ecole Normale Supérieure de Lyon, France.

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https://academic.oup.com/jid/article-lookup/doi/10.1093/infd
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http://dx.doi.org/10.1093/infdis/jiv268DOI Listing
October 2015

VACCINES. Ebola virus vaccines--preparing for the unexpected.

Science 2015 Aug;349(6249):693-4

Institut für Virologie, Philipps-Universität Marburg, Germany.

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http://dx.doi.org/10.1126/science.aad0681DOI Listing
August 2015

The hemagglutinin: a determinant of pathogenicity.

Curr Top Microbiol Immunol 2014 ;385:3-34

Institut für Virologie, Philipps-Universität, Hans-Meerwein-Str. 2, 35043, Marburg, Germany.

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http://dx.doi.org/10.1007/82_2014_384DOI Listing
March 2015

SnapShot: Evolution of human influenza A viruses.

Cell Host Microbe 2015 Mar;17(3):416-416.e1

Institut für Virologie, Hans-Meerwein-Strasse 2, 35043 Marburg, Germany.

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http://dx.doi.org/10.1016/j.chom.2015.02.001DOI Listing
March 2015

Filovirus RefSeq entries: evaluation and selection of filovirus type variants, type sequences, and names.

Viruses 2014 Sep 26;6(9):3663-82. Epub 2014 Sep 26.

IViral Special Pathogens Branch, Division of High-Consequence Pathogens Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.

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http://dx.doi.org/10.3390/v6093663DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189044PMC
September 2014

Lessons to be learned from the ebolavirus outbreak in West Africa.

Emerg Microbes Infect 2014 Aug 27;3(8):e61. Epub 2014 Aug 27.

Philipps-Universität Marburg, Institut für Virologie, Hans-Meerwein-Str. 2 , D-35043 Marburg, Germany.

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http://dx.doi.org/10.1038/emi.2014.68DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150288PMC
August 2014

Influenza viruses en route from birds to man.

Cell Host Microbe 2014 Jun;15(6):653-4

Institut für Virologie, Philipps-Universität Marburg, 35043 Marburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2014.05.019DOI Listing
June 2014

Activation of influenza A viruses by host proteases from swine airway epithelium.

J Virol 2014 Jan 23;88(1):282-91. Epub 2013 Oct 23.

Institute of Virology, Philipps University Marburg, Marburg, Germany.

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http://dx.doi.org/10.1128/JVI.01635-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3911738PMC
January 2014

Adaptive mutations in the H5N1 polymerase complex.

Virus Res 2013 Dec 1;178(1):53-62. Epub 2013 Jun 1.

Heinrich-Pette-Institute, Leibniz Institute for Experimental Virology, Hamburg, Germany.

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http://dx.doi.org/10.1016/j.virusres.2013.05.010DOI Listing
December 2013

Activation of influenza viruses by proteases from host cells and bacteria in the human airway epithelium.

Pathog Dis 2013 Nov 2;69(2):87-100. Epub 2013 Jul 2.

Institute of Virology, Philipps-University Marburg, Marburg, Germany.

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http://dx.doi.org/10.1111/2049-632X.12053DOI Listing
November 2013

The synergies of microorganisms enlightened - convergent approaches to delineating coinfections.

Pathog Dis 2013 Nov;69(2):71

Institut für Virologie, Philipps-Universität, Marburg, Germany.

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http://dx.doi.org/10.1111/2049-632X.12101DOI Listing
November 2013

Influenza virus budding from the tips of cellular microvilli in differentiated human airway epithelial cells.

J Gen Virol 2013 May 3;94(Pt 5):971-6. Epub 2013 Jan 3.

Institute of Virology, Philipps University Marburg, Hans-Meerwein-Str. 2, 35043 Marburg, Germany.

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http://dx.doi.org/10.1099/vir.0.049239-0DOI Listing
May 2013

H7N9 avian influenza virus - search and re-search.

Emerg Microbes Infect 2013 Apr;2(4):e18

Philipps-Universität Marburg, Institut für Virologie , D-35043 Marburg, Germany.

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http://dx.doi.org/10.1038/emi.2013.18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636592PMC
April 2013

The microtubule motor protein KIF13A is involved in intracellular trafficking of the Lassa virus matrix protein Z.

Cell Microbiol 2013 Feb 10;15(2):315-34. Epub 2013 Jan 10.

Institute of Virology, Philipps-University Marburg, Hans-Meerwein-Str. 2, 35043 Marburg, Germany.

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http://dx.doi.org/10.1111/cmi.12095DOI Listing
February 2013

Welcome from the Editors-in-Chief.

Emerg Microbes Infect 2012 Jul;1(7):e1

Philipps-Universität Marburg, Institut für Virologie , Hans-Meerwein-Str. 2, D-35043 Marburg, Germany.

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http://dx.doi.org/10.1038/emi.2012.13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630911PMC
July 2012

Influenza B virus with modified hemagglutinin cleavage site as a novel attenuated live vaccine.

J Infect Dis 2011 Nov 14;204(10):1483-90. Epub 2011 Sep 14.

Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald, Insel Riems, Germany.

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http://dx.doi.org/10.1093/infdis/jir613DOI Listing
November 2011

Aprotinin, a protease inhibitor, suppresses proteolytic activation of pandemic H1N1v influenza virus.

Antivir Chem Chemother 2011 Mar 7;21(4):169-74. Epub 2011 Mar 7.

DI Ivanovsky Institute of Virology, Moscow, Russia.

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http://dx.doi.org/10.3851/IMP1715DOI Listing
March 2011

[Flu outbreaks. Influenza viruses on the way from animal to man].

Pharm Unserer Zeit 2011 Mar;40(2):104-8

Philipps-Universität Marburg, Institut für Virologie, Hans-Meerwein-Str. 2, D-35043 Marburg.

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March 2011

Modification of nonstructural protein 1 of influenza A virus by SUMO1.

J Virol 2011 Jan 3;85(2):1086-98. Epub 2010 Nov 3.

Laboratory of Molecular Virology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, 225 South Chongqing Road, Shanghai 200025, China.

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http://dx.doi.org/10.1128/JVI.00877-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020006PMC
January 2011

Differential use of importin-α isoforms governs cell tropism and host adaptation of influenza virus.

Nat Commun 2011 Jan;2:156

1] Heinrich-Pette-Institute, Leibniz Institute for Experimental Virology, Hamburg, Germany. [2] Sir William Dunn School of Pathology, University of Oxford, Oxford, UK. [3] Institute of Virology, Philipps-University Marburg, Marburg, Germany.

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http://edoc.mdc-berlin.de/11477/3/11477oa.pdf
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http://www.nature.com/doifinder/10.1038/ncomms1158
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http://dx.doi.org/10.1038/ncomms1158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105303PMC
January 2011

Influenza A virus replication induces cell cycle arrest in G0/G1 phase.

J Virol 2010 Dec 22;84(24):12832-40. Epub 2010 Sep 22.

Key Laboratory of Molecular Virology & Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, 225 South Chongqing Road, Shanghai 200025, China.

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http://dx.doi.org/10.1128/JVI.01216-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004346PMC
December 2010

Intracellular distribution of NS1 correlates with the infectivity and interferon antagonism of an avian influenza virus (H7N1).

J Virol 2010 Nov 15;84(22):11858-65. Epub 2010 Sep 15.

Institut fuer Virologie, Klinikum der Philipps-Universität Marburg, Postfach 2360, 35011 Marburg, Germany.

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http://dx.doi.org/10.1128/JVI.01011-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977857PMC
November 2010

Alterations in caspase cleavage motifs of NP and M2 proteins attenuate virulence of a highly pathogenic avian influenza virus.

Virology 2009 Nov 10;394(1):57-63. Epub 2009 Sep 10.

D.I. Ivanovsky Institute of Virology, Gamaleya 16, Moscow 123098, Russia.

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http://dx.doi.org/10.1016/j.virol.2009.08.013DOI Listing
November 2009

Spread of infection and lymphocyte depletion in mice depends on polymerase of influenza virus.

Am J Pathol 2009 Sep 21;175(3):1178-86. Epub 2009 Aug 21.

Heinrich-Pette-Institut für Experimentelle Virologie und Immunologie, an der Universität Hamburg, Martinistrasse 52, Hamburg, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S00029440106062
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http://dx.doi.org/10.2353/ajpath.2009.090339DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731136PMC
September 2009

Functional significance of the hemadsorption activity of influenza virus neuraminidase and its alteration in pandemic viruses.

Arch Virol 2009 21;154(6):945-57. Epub 2009 May 21.

Institute of Virology, Philipps University, Hans-Meerwein-Str.2, 35043, Marburg, Germany.

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http://dx.doi.org/10.1007/s00705-009-0393-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2691527PMC
June 2009

Rapid and reliable universal cloning of influenza A virus genes by target-primed plasmid amplification.

Nucleic Acids Res 2008 Dec 2;36(21):e139. Epub 2008 Oct 2.

Friedrich-Loeffler-Institute, Federal Research Institute for Animal Health, Greifswald-Insel Riems, Germany.

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http://dx.doi.org/10.1093/nar/gkn646DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2588516PMC
December 2008

Glycoprotein targeting signals influence the distribution of measles virus envelope proteins and virus spread in lymphocytes.

J Gen Virol 2008 Mar;89(Pt 3):687-96

Institute of Virology, Philipps University Marburg, Hans-Meerwein-Str. 2, D-35043 Marburg, Germany.

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http://jgv.microbiologyresearch.org/content/journal/jgv/10.1
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http://dx.doi.org/10.1099/vir.0.83407-0DOI Listing
March 2008

Forty years of marburg virus.

J Infect Dis 2007 Nov;196 Suppl 2:S131-5

Institute for Virology, Philipps-Universitat Marburg, Marburg, 35043, Germany.

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http://dx.doi.org/10.1086/520551DOI Listing
November 2007

Assessment of a vesicular stomatitis virus-based vaccine by use of the mouse model of Ebola virus hemorrhagic fever.

J Infect Dis 2007 Nov;196 Suppl 2:S404-12

Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Canada.

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https://academic.oup.com/jid/article-lookup/doi/10.1086/5205
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http://dx.doi.org/10.1086/520591DOI Listing
November 2007

Control of apoptosis in influenza virus-infected cells by up-regulation of Akt and p53 signaling.

Apoptosis 2007 Aug;12(8):1419-32

D.I. Ivanovsky Institute of Virology, Moscow 123098, Russia.

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http://dx.doi.org/10.1007/s10495-007-0071-yDOI Listing
August 2007

Amino acids from both N-terminal hydrophobic regions of the Lassa virus envelope glycoprotein GP-2 are critical for pH-dependent membrane fusion and infectivity.

J Gen Virol 2007 Aug;88(Pt 8):2320-8

The Institute for Virology, Philipps University, Hans-Meerwein-Strasse 3, 35043 Marburg, Germany.

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http://dx.doi.org/10.1099/vir.0.82950-0DOI Listing
August 2007

A new approach to an influenza life vaccine: haemagglutinin cleavage site mutants generated by reverse genetics.

Berl Munch Tierarztl Wochenschr 2006 Mar-Apr;119(3-4):186-91

Institut für Virologie, Universitätsklinikum Giessen und Marburg, Germany.

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May 2007

Avian-virus-like receptor specificity of the hemagglutinin impedes influenza virus replication in cultures of human airway epithelium.

Virology 2007 May 17;361(2):384-90. Epub 2007 Jan 17.

Institute of Virology, Philipps University, 35043 Marburg, Germany.

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http://dx.doi.org/10.1016/j.virol.2006.11.030DOI Listing
May 2007

Measles virus nucleocapsid transport to the plasma membrane requires stable expression and surface accumulation of the viral matrix protein.

Cell Microbiol 2007 May 9;9(5):1203-14. Epub 2007 Jan 9.

Institute of Virology, Philipps-University Marburg, Hans-Meerwein-Strasse 2, D-35043 Marburg, Germany.

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http://dx.doi.org/10.1111/j.1462-5822.2006.00860.xDOI Listing
May 2007

New low-viscosity overlay medium for viral plaque assays.

Virol J 2006 Aug 31;3:63. Epub 2006 Aug 31.

Institute of Virology, Philipps University, Hans-Meerwein-Str, 3, 35043 Marburg, Germany.

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http://dx.doi.org/10.1186/1743-422X-3-63DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1564390PMC
August 2006

Gangliosides are not essential for influenza virus infection.

Glycoconj J 2006 Feb;23(1-2):107-13

Institute of Virology, Philipps University, Robert Koch str. 17, 35037, Marburg, Germany.

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http://dx.doi.org/10.1007/s10719-006-5443-yDOI Listing
February 2006

VP24 of Marburg virus influences formation of infectious particles.

J Virol 2005 Nov;79(21):13421-33

Institut für Virologie der Philipps-Universität Marburg, Robert-Koch-Strasse 17, D-35037 Marburg, Germany.

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http://dx.doi.org/10.1128/JVI.79.21.13421-13433.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1262563PMC
November 2005

Polymorphism of filovirus glycoproteins.

Adv Virus Res 2005 ;64:359-81

Biologie des Filovirus, Claude Bernard University Lyon, INSERM U412 69365 Lyon, France.

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http://dx.doi.org/10.1016/S0065-3527(05)64011-0DOI Listing
October 2005

The nipah virus fusion protein is cleaved within the endosomal compartment.

J Biol Chem 2005 Aug 16;280(33):29899-903. Epub 2005 Jun 16.

Institute of Virology, Philipps University of Marburg, Germany.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M504598200
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http://dx.doi.org/10.1074/jbc.M504598200DOI Listing
August 2005

Infection of the endothelium by influenza viruses.

Thromb Haemost 2005 Aug;94(2):262-5

Institut für Virologie, Philipps-Universität, Marburg, Germany.

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http://dx.doi.org/10.1160/TH05-04-0264DOI Listing
August 2005

Live attenuated recombinant vaccine protects nonhuman primates against Ebola and Marburg viruses.

Nat Med 2005 Jul 5;11(7):786-90. Epub 2005 Jun 5.

Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, 1015 Arlington Street, Winnipeg, Manitoba R3E 3R2, Canada.

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http://www.dtic.mil/dtic/tr/fulltext/u2/a435168.pdf
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http://www.nature.com/doifinder/10.1038/nm1258
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http://dx.doi.org/10.1038/nm1258DOI Listing
July 2005

Threat of infection: microbes of high pathogenic potential--strategies for detection, control and eradication.

Int J Med Microbiol 2005 Jun;295(3):141-51

Research Center for Infectious Diseases, University of Würzburg, Germany.

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http://dx.doi.org/10.1016/j.ijmm.2005.03.004DOI Listing
June 2005

Inhibition of Marburg virus protein expression and viral release by RNA interference.

J Gen Virol 2005 Apr;86(Pt 4):1181-8

Max Planck Institute for Infection Biology, Schumannstrasse 21/22, Campus Charité Mitte, 10117 Berlin, Germany.

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http://dx.doi.org/10.1099/vir.0.80622-0DOI Listing
April 2005

Ectodomain shedding of the glycoprotein GP of Ebola virus.

EMBO J 2004 May 22;23(10):2175-84. Epub 2004 Apr 22.

Institut für Virologie, Philipps-Universität Marburg, Marburg, Germany.

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http://dx.doi.org/10.1038/sj.emboj.7600219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC424403PMC
May 2004

Polarized glycoprotein targeting affects the spread of measles virus in vitro and in vivo.

J Gen Virol 2004 Apr;85(Pt 4):1019-27

Institute of Virology, Philipps University Marburg, Robert-Koch-Str 17, 35037 Marburg, Germany.

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http://dx.doi.org/10.1099/vir.0.19663-0DOI Listing
April 2004

Lassa virus glycoprotein signal peptide displays a novel topology with an extended endoplasmic reticulum luminal region.

J Biol Chem 2004 Mar 6;279(13):12293-9. Epub 2004 Jan 6.

Institut für Virologie der Philipps-Universität Marburg, Robert-Koch-Strasse 17, D-35037 Marburg, Germany.

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http://dx.doi.org/10.1074/jbc.M312975200DOI Listing
March 2004

In memoriam Rudolf Rott (1926-2003).

Arch Virol 2003 Dec 1;148(12):2489-91. Epub 2003 Jan 1.

Philipps-Universitat, Marburg, Germany.

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http://dx.doi.org/10.1007/s00705-003-0239-xDOI Listing
December 2003

SARS--beginning to understand a new virus.

Nat Rev Microbiol 2003 Dec;1(3):209-18

IRIS, Chiron S.r.l., Via Fiorentina 1, 53100 Siena, Italy.

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http://dx.doi.org/10.1038/nrmicro775DOI Listing
December 2003

Identification of Lassa virus glycoprotein signal peptide as a trans-acting maturation factor.

EMBO Rep 2003 Nov 10;4(11):1084-8. Epub 2003 Oct 10.

Institut für Virologie der Philipps-Universität Marburg, Robert-Koch-Strasse 17, D-35037 Marburg, Germany.

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http://dx.doi.org/10.1038/sj.embor.embor7400002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1326372PMC
November 2003

Ebola virus: from discovery to vaccine.

Nat Rev Immunol 2003 Aug;3(8):677-85

Department of Medical Microbiology, University of Manitoba, Winnipeg, Canada.

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http://dx.doi.org/10.1038/nri1154DOI Listing
August 2003