Hans Vasen

Hans Vasen

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Interim Results from the IMPACT Study: Evidence for Prostate-specific Antigen Screening in BRCA2 Mutation Carriers.

Authors:
Elizabeth C Page Elizabeth K Bancroft Mark N Brook Melissa Assel Mona Hassan Al Battat Sarah Thomas Natalie Taylor Anthony Chamberlain Jennifer Pope Holly Ni Raghallaigh D Gareth Evans Jeanette Rothwell Lovise Maehle Eli Marie Grindedal Paul James Lyon Mascarenhas Joanne McKinley Lucy Side Tessy Thomas Christi van Asperen Hans Vasen Lambertus A Kiemeney Janneke Ringelberg Thomas Dyrsø Jensen Palle J S Osther Brian T Helfand Elena Genova Rogier A Oldenburg Cezary Cybulski Dominika Wokolorczyk Kai-Ren Ong Camilla Huber Jimmy Lam Louise Taylor Monica Salinas Lidia Feliubadaló Jan C Oosterwijk Wendy van Zelst-Stams Jackie Cook Derek J Rosario Susan Domchek Jacquelyn Powers Saundra Buys Karen O'Toole Margreet G E M Ausems Rita K Schmutzler Kerstin Rhiem Louise Izatt Vishakha Tripathi Manuel R Teixeira Marta Cardoso William D Foulkes Armen Aprikian Heleen van Randeraad Rosemarie Davidson Mark Longmuir Mariëlle W G Ruijs Apollonia T J M Helderman van den Enden Muriel Adank Rachel Williams Lesley Andrews Declan G Murphy Dorothy Halliday Lisa Walker Annelie Liljegren Stefan Carlsson Ashraf Azzabi Irene Jobson Catherine Morton Kylie Shackleton Katie Snape Helen Hanson Marion Harris Marc Tischkowitz Amy Taylor Judy Kirk Rachel Susman Rakefet Chen-Shtoyerman Allan Spigelman Nicholas Pachter Munaza Ahmed Teresa Ramon Y Cajal Janez Zgajnar Carole Brewer Neus Gadea Angela F Brady Theo van Os David Gallagher Oskar Johannsson Alan Donaldson Julian Barwell Nicola Nicolai Eitan Friedman Elias Obeid Lynn Greenhalgh Vedang Murthy Lucia Copakova Sibel Saya John McGrath Peter Cooke Karina Rønlund Kate Richardson Alex Henderson Soo H Teo Banu Arun Karin Kast Alexander Dias Neil K Aaronson Audrey Ardern-Jones Chris H Bangma Elena Castro David Dearnaley Diana M Eccles Karen Tricker Jorunn Eyfjord Alison Falconer Christopher Foster Henrik Gronberg Freddie C Hamdy Vigdis Stefansdottir Vincent Khoo Geoffrey J Lindeman Jan Lubinski Karol Axcrona Christos Mikropoulos Anita Mitra Clare Moynihan Gadi Rennert Mohnish Suri Penny Wilson Tim Dudderidge Judith Offman Zsofia Kote-Jarai Andrew Vickers Hans Lilja Rosalind A Eeles

Eur Urol 2019 Dec 16;76(6):831-842. Epub 2019 Sep 16.

Oncogenetics Team, Institute of Cancer Research, London, UK; Cancer Genetics Unit and Academic Urology Unit, Royal Marsden NHS Foundation Trust, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2019.08.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880781PMC
December 2019

Effect of chromoendoscopy in the proximal colon on colorectal neoplasia detection in Lynch syndrome: a multicenter randomized controlled trial.

Gastrointest Endosc 2019 10 24;90(4):624-632. Epub 2019 Apr 24.

Department of Gastroenterology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.

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http://dx.doi.org/10.1016/j.gie.2019.04.227DOI Listing
October 2019

Screening of Individuals at High Risk for Pancreatic Cancer.

Clin Gastroenterol Hepatol 2019 Aug 19;17(9):1916-1917. Epub 2019 Mar 19.

Department of Medical Oncology, Ramon y Cajal University Hospital, Ramón y Cajal Health Research Institute, Centro de Investigación Biomédica en Red Cáncer, Alcala University, Madrid, Spain.

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http://dx.doi.org/10.1016/j.cgh.2019.03.023DOI Listing
August 2019

Endoscopic full thickness resection for early colon cancer in Lynch syndrome.

Fam Cancer 2019 07;18(3):349-352

Department of Gastroenterology and Hepatology, Leiden University Medical Centre, PO Box 9600, 2300 RC, Leiden, The Netherlands.

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http://dx.doi.org/10.1007/s10689-019-00132-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6559999PMC
July 2019

Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database.

Genet Med 2019 Jul 24. Epub 2019 Jul 24.

Department of Tumor Biology, Institute of Cancer Research, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway.

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http://dx.doi.org/10.1038/s41436-019-0596-9DOI Listing
July 2019

Optimizing the timing of colorectal surgery in patients with familial adenomatous polyposis in clinical practice.

Scand J Gastroenterol 2019 Jun 11;54(6):733-739. Epub 2019 Aug 11.

Department of Gastroenterology & Hepatology, Leiden University Medical Centre , Leiden , The Netherlands.

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http://dx.doi.org/10.1080/00365521.2019.1621930DOI Listing
June 2019

Lack of association between screening interval and cancer stage in Lynch syndrome may be accounted for by over-diagnosis; a prospective Lynch syndrome database report.

Hered Cancer Clin Pract 2019 28;17. Epub 2019 Feb 28.

4Department of Tumor Biology, Institute of Cancer Research, The Norwegian Radium Hospital, part of Oslo University Hospital, Olso, Norway.

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https://hccpjournal.biomedcentral.com/articles/10.1186/s1305
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http://dx.doi.org/10.1186/s13053-019-0106-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394091PMC
February 2019

Cancer Risks for PMS2-Associated Lynch Syndrome.

J Clin Oncol 2018 10 30;36(29):2961-2968. Epub 2018 Aug 30.

Sanne W. ten Broeke, Heleen M. van der Klift, Carli M.J. Tops, Manon Suerink, Frederik J. Hes, Hans F.A. Vasen, Juul T. Wijnen, and Maartje Nielsen, Leiden University Medical Center, Leiden; Encarna Gomez Garcia, Maastricht University Medical Center, Maastricht; Nicoline Hoogerbrugge, Arjen R. Mensenkamp, and Liesbeth Spruijt, Radboud University Medical Center, Nijmegen; Tom G.W. Letteboer, University Medical Center, Utrecht; Theo A.M. van Os and Egbert J.W. Redeker, Academic Medical Center, Amsterdam; Maran J.W. Olderode-Berends and Yvonne J. Vos, University of Groningen; University Medical Center Groningen, Groningen; Anja Wagner, Erasmus Medical Center, Rotterdam, the Netherlands; Stefan Aretz, University of Bonn; University Hospital Bonn, Bonn; Christoph Engel, Leipzig University; Medizinisch Genetisches Zentrum Bayerstr, Leipzig; Magnus von Knebel Doeberitz, University of Heidelberg; German Cancer Research Center, Heidelberg; Pål Møller, University of Witten-Herdecke, Wuppertal; Nils Rahner, Heinrich-Heine-University, Düsseldorf; Hans K. Schackert, Technische Universität Dresden, Dresden; Verena Steinke-Lange, Medizinische Klinik und Poliklinik IV Campus Innenstadt, Klinikum der Universität München, Munich, Germany; Pål Møller, The Norwegian Radium Hospital; Oslo University Hospital, Oslo, Norway; Inge Bernstein, Hvidovre Hospital, Hvidovre, and Aalborg University Hospital, Aalborg, Denmark; Daniel D. Buchanan, Mark Clendenning, John L. Hopper, Mark A. Jenkins, Christophe Rosty, Ingrid Winship, and Aung Ko Win, The University of Melbourne; Daniel D. Buchanan, Ingrid Winship, and Aung Ko Win, Royal Melbourne Hospital, Parkville, Melbourne, Victoria; Rodney Scott, University of Newcastle, Newcastle, New South Wales, Australia; Albert de la Chapelle, Heather L. Hampel, Rachel Pearlman, and Leigha Senter, The Ohio State University Comprehensive Cancer Center, Columbus, OH; Gabriel Capella and Marta Pineda, Institut d'Investigació Biomédica de Bellvitge, Barcelona, Spain; Steven Gallinger, Mount Sinai Hospital, Toronto, Ontario, Canada; Jane C. Figueiredo and Robert Haile, Cedars-Sinai Medical Center, Los Angeles, CA; Loic Le Marchand, University of Hawaii Cancer Center, Honolulu, HI; Annika Lindblom, Karolinska Institutet; Karolinska University Hospital, Stockholm, Sweden; Noralane M. Lindor, Mayo Clinic Arizona, Scottsdale, AZ; Polly A. Newcomb, Fred Hutchinson Cancer Research Center; University of Washington, Seattle, WA; and Stephen Thibodeau, Mayo Clinic, Rochester, MN.

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http://ascopubs.org/doi/10.1200/JCO.2018.78.4777
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http://dx.doi.org/10.1200/JCO.2018.78.4777DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349460PMC
October 2018

Features of incident colorectal cancer in Lynch syndrome.

United European Gastroenterol J 2018 Oct 11;6(8):1215-1222. Epub 2018 Jun 11.

Department of Gastroenterology & Hepatology, Leiden University Medical Center, Leiden, The Netherlands.

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http://journals.sagepub.com/doi/10.1177/2050640618783554
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http://dx.doi.org/10.1177/2050640618783554DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169044PMC
October 2018

High Growth Rate of Pancreatic Ductal Adenocarcinoma in Mutation Carriers.

Cancer Prev Res (Phila) 2018 09 10;11(9):551-556. Epub 2018 Jul 10.

Department of Gastroenterology and Hepatology, Leiden University Medical Centre, Leiden, the Netherlands.

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http://dx.doi.org/10.1158/1940-6207.CAPR-18-0035DOI Listing
September 2018

Prostate-specific antigen velocity in a prospective prostate cancer screening study of men with genetic predisposition.

Authors:
Christos Mikropoulos Christina G Hutten Selkirk Sibel Saya Elizabeth Bancroft Emily Vertosick Tokhir Dadaev Charles Brendler Elizabeth Page Alexander Dias D Gareth Evans Jeanette Rothwell Lovise Maehle Karol Axcrona Kate Richardson Diana Eccles Thomas Jensen Palle J Osther Christi J van Asperen Hans Vasen Lambertus A Kiemeney Janneke Ringelberg Cezary Cybulski Dominika Wokolorczyk Rachel Hart Wayne Glover Jimmy Lam Louise Taylor Monica Salinas Lidia Feliubadaló Rogier Oldenburg Ruben Cremers Gerald Verhaegh Wendy A van Zelst-Stams Jan C Oosterwijk Jackie Cook Derek J Rosario Saundra S Buys Tom Conner Susan Domchek Jacquelyn Powers Margreet G E M Ausems Manuel R Teixeira Sofia Maia Louise Izatt Rita Schmutzler Kerstin Rhiem William D Foulkes Talia Boshari Rosemarie Davidson Marielle Ruijs Apollonia T J M Helderman-van den Enden Lesley Andrews Lisa Walker Katie Snape Alex Henderson Irene Jobson Geoffrey J Lindeman Annelie Liljegren Marion Harris Muriel A Adank Judy Kirk Amy Taylor Rachel Susman Rakefet Chen-Shtoyerman Nicholas Pachter Allan Spigelman Lucy Side Janez Zgajnar Josefina Mora Carole Brewer Neus Gadea Angela F Brady David Gallagher Theo van Os Alan Donaldson Vigdis Stefansdottir Julian Barwell Paul A James Declan Murphy Eitan Friedman Nicola Nicolai Lynn Greenhalgh Elias Obeid Vedang Murthy Lucia Copakova John McGrath Soo-Hwang Teo Sara Strom Karin Kast Daniel A Leongamornlert Anthony Chamberlain Jenny Pope Anna C Newlin Neil Aaronson Audrey Ardern-Jones Chris Bangma Elena Castro David Dearnaley Jorunn Eyfjord Alison Falconer Christopher S Foster Henrik Gronberg Freddie C Hamdy Oskar Johannsson Vincent Khoo Jan Lubinski Eli Marie Grindedal Joanne McKinley Kylie Shackleton Anita V Mitra Clare Moynihan Gad Rennert Mohnish Suri Karen Tricker Sue Moss Zsofia Kote-Jarai Andrew Vickers Hans Lilja Brian T Helfand Rosalind A Eeles

Br J Cancer 2018 03 6;118(6):e17. Epub 2018 Mar 6.

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http://dx.doi.org/10.1038/bjc.2018.11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877440PMC
March 2018

The importance of a well-structured pancreatic screening program for familial and hereditary pancreatic cancer.

Authors:
Hans F A Vasen

Fam Cancer 2018 01;17(1):1-3

Department of Gastroenterology and Hepatology, Leiden University Medical Centre, Leiden, The Netherlands.

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http://link.springer.com/10.1007/s10689-017-0066-y
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http://dx.doi.org/10.1007/s10689-017-0066-yDOI Listing
January 2018

Prostate-specific antigen velocity in a prospective prostate cancer screening study of men with genetic predisposition.

Authors:
Christos Mikropoulos Christina G Hutten Selkirk Sibel Saya Elizabeth Bancroft Emily Vertosick Tokhir Dadaev Charles Brendler Elizabeth Page Alexander Dias D Gareth Evans Jeanette Rothwell Lovise Maehle Karol Axcrona Kate Richardson Diana Eccles Thomas Jensen Palle J Osther Christi J van Asperen Hans Vasen Lambertus A Kiemeney Janneke Ringelberg Cezary Cybulski Dominika Wokolorczyk Rachel Hart Wayne Glover Jimmy Lam Louise Taylor Monica Salinas Lidia Feliubadaló Rogier Oldenburg Ruben Cremers Gerald Verhaegh Wendy A van Zelst-Stams Jan C Oosterwijk Jackie Cook Derek J Rosario Saundra S Buys Tom Conner Susan Domchek Jacquelyn Powers Margreet Gem Ausems Manuel R Teixeira Sofia Maia Louise Izatt Rita Schmutzler Kerstin Rhiem William D Foulkes Talia Boshari Rosemarie Davidson Marielle Ruijs Apollonia Tjm Helderman-van den Enden Lesley Andrews Lisa Walker Katie Snape Alex Henderson Irene Jobson Geoffrey J Lindeman Annelie Liljegren Marion Harris Muriel A Adank Judy Kirk Amy Taylor Rachel Susman Rakefet Chen-Shtoyerman Nicholas Pachter Allan Spigelman Lucy Side Janez Zgajnar Josefina Mora Carole Brewer Neus Gadea Angela F Brady David Gallagher Theo van Os Alan Donaldson Vigdis Stefansdottir Julian Barwell Paul A James Declan Murphy Eitan Friedman Nicola Nicolai Lynn Greenhalgh Elias Obeid Vedang Murthy Lucia Copakova John McGrath Soo-Hwang Teo Sara Strom Karin Kast Daniel A Leongamornlert Anthony Chamberlain Jenny Pope Anna C Newlin Neil Aaronson Audrey Ardern-Jones Chris Bangma Elena Castro David Dearnaley Jorunn Eyfjord Alison Falconer Christopher S Foster Henrik Gronberg Freddie C Hamdy Oskar Johannsson Vincent Khoo Jan Lubinski Eli Marie Grindedal Joanne McKinley Kylie Shackleton Anita V Mitra Clare Moynihan Gad Rennert Mohnish Suri Karen Tricker Sue Moss Zsofia Kote-Jarai Andrew Vickers Hans Lilja Brian T Helfand Rosalind A Eeles

Br J Cancer 2018 01 4;118(2):266-276. Epub 2018 Jan 4.

The Institute of Cancer Research, 15 Cotswold Road, Sutton, Surrey SM2 5NG, UK.

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http://dx.doi.org/10.1038/bjc.2017.429DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785754PMC
January 2018

Inflammatory potential of the diet and colorectal tumor risk in persons with Lynch syndrome.

Am J Clin Nutr 2017 Nov 20;106(5):1287-1294. Epub 2017 Sep 20.

Division of Human Nutrition, Wageningen University & Research, Wageningen, Netherlands;

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http://dx.doi.org/10.3945/ajcn.117.152900DOI Listing
November 2017

Colonoscopy in Lynch syndrome: the need for a new quality score.

Fam Cancer 2017 04;16(2):239-241

Department of Gastroenterology and Hepatology, Leiden University Medical Centre, PO Box 9600, 2300 RC, Leiden, The Netherlands.

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http://dx.doi.org/10.1007/s10689-016-9950-0DOI Listing
April 2017

Dilemmas in the management of screen-detected lesions in patients at high risk for pancreatic cancer.

Fam Cancer 2017 01;16(1):111-115

Department of Gastroenterology and Hepatology, Leiden University Medical Centre, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.

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http://dx.doi.org/10.1007/s10689-016-9915-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5243878PMC
January 2017

The clinical phenotype of hereditary versus sporadic prostate cancer: HPC definition revisited.

Prostate 2016 07 14;76(10):897-904. Epub 2016 Mar 14.

Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands.

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http://doi.wiley.com/10.1002/pros.23179
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http://dx.doi.org/10.1002/pros.23179DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069637PMC
July 2016

Benefit of Surveillance for Pancreatic Cancer in High-Risk Individuals: Outcome of Long-Term Prospective Follow-Up Studies From Three European Expert Centers.

J Clin Oncol 2016 06 25;34(17):2010-9. Epub 2016 Apr 25.

Hans Vasen, Isaura Ibrahim, Kristin Robbers, Anneke M. van Mil, Thomas Potjer, Bert A. Bonsing, Wilma Bergman, Martin Wasser, and Hans Morreau, Leiden University Medical Center, Leiden; Wouter H. de Vos tot Nederveen Cappel, Isala Clinics, Zwolle, the Netherlands; Carmen Guillen Ponce, Alfredo Carrato, Julie Earl, Evelina Mocci, Enrique Vazquez-Sequeiros, Alfonso Sanjuanbenito, Maria Muñoz-Beltran, and José Montans, Ramón y Cajal University Hospital, Ramón y Cajal Health Research Institute, Madrid, Spain; Emily P. Slater, Elvira Matthäi, Volker Fendrich, and Detlef K. Bartsch, University Hospital Marburg; Christoph Schicker, Martin Steinkamp, and Jens Figiel, Philipps University Marburg, Marburg; Günter Klöppel, Consultation Centre for Pancreatic and Endocrine Tumors, Technical University Munich; Peter Langer, Klinikum Hanau, Hanau, Germany; and Irene Esposito, Innsbruck University Hospital, Innsbruck, Austria.

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http://dx.doi.org/10.1200/JCO.2015.64.0730DOI Listing
June 2016

Constitutional or biallelic? Settling on a name for a recessively inherited cancer susceptibility syndrome.

J Med Genet 2016 Apr 3;53(4):226. Epub 2015 Jun 3.

Department of Gastroenterology & Hepatology, Leiden University Medical Centre, Leiden, The Netherlands.

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http://dx.doi.org/10.1136/jmedgenet-2015-103249DOI Listing
April 2016

Loss-of-Function Mutations in the Cell-Cycle Control Gene CDKN2A Impact on Glucose Homeostasis in Humans.

Diabetes 2016 Feb 5;65(2):527-33. Epub 2015 Nov 5.

Oxford Centre for Diabetes, Endocrinology & Metabolism, University of Oxford, Oxford, U.K. Oxford National Institute for Health Research Biomedical Research Centre, Churchill Hospital, Oxford, U.K.

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http://dx.doi.org/10.2337/db15-0602DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724950PMC
February 2016

Massive gastric polyposis associated with a germline SMAD4 gene mutation.

Fam Cancer 2015 Dec;14(4):569-73

Department of Gastroenterology and Hepatology, Isala Clinics, P.O. Box 10400, 8000 GK, Zwolle, The Netherlands.

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http://dx.doi.org/10.1007/s10689-015-9822-zDOI Listing
December 2015

Randomized Comparison of Surveillance Intervals in Familial Colorectal Cancer.

J Clin Oncol 2015 Dec 2;33(35):4188-93. Epub 2015 Nov 2.

Simone D. Hennink, Andrea E. van der Meulen-de Jong, Ron Wolterbeek, A. Stijn L.P. Crobach, Roeland A. Veenendaal, Hans Morreau, and Hans F.A. Vasen, Leiden University Medical Center; Wiet F.S.J. Crobach, W. Rogier ten Hove, and Anne M.C. Witte, Diaconessenhuis, Leiden; Marco C.J.M. Becx, St Antonius Hospital, Nieuwegein; Michiel van Haastert and Hugo J. Wolters, Martini Hospital; Jan H. Kleibeuker, University Medical Center Groningen, Groningen; Maarten A.C. Meijssen, Juda Vecht, Wouter H. de Vos tot Nederveen Cappel, and Dik Westerveld, Isala Clinics, Zwolle; Fokko M. Nagengast, Radboud University Medical Center, Nijmegen; Marno C.M. Rijk, Amphia Hospital, Breda; Jan M.J.I. Salemans and Marie-Louise Verhulst, Máxima Medical Center; Arnold Stronkhorst, Catharina Hospital, Eindhoven; Hans A.R.E. Tuynman, Medical Center Alkmaar, Alkmaar; Herman Walinga, Reinier de Graaf Gasthuis, Delft; Olaf K. Weinhardt, Scheper Hospital, Emmen; and Annemieke Cats, National Cancer Institute, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1200/JCO.2015.62.2035DOI Listing
December 2015

Familial Pancreatic Cancer: To Screen or not to Screen?

EBioMedicine 2015 Dec 17;2(12):1858-9. Epub 2015 Dec 17.

Department of Visceral-, Thoracic- and Vascular Surgery, University Hospital Marburg, Marburg, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S23523964150019
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http://dx.doi.org/10.1016/j.ebiom.2015.12.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703731PMC
December 2015

Obesity, Aspirin, and Risk of Colorectal Cancer in Carriers of Hereditary Colorectal Cancer: A Prospective Investigation in the CAPP2 Study.

J Clin Oncol 2015 Nov 17;33(31):3591-7. Epub 2015 Aug 17.

Mohammad Movahedi, Beheshti University of Medical Sciences, Tehran, Iran; Mohammad Movahedi and D. Timothy Bishop, University of Leeds, Leeds; Diana Eccles, University of Southampton, Southampton; D. Gareth Evans, St Mary's Hospital, Manchester; Eamonn R. Maher, University of Birmingham, Birmingham; Malcolm G. Dunlop, Western General Hospital, Edinburgh; Shirley V. Hodgson, St George's Hospital; Lucy Side, University College London; Huw J.W. Thomas, St Mark's Hospital, Imperial College, London; Patrick J. Morrison, Queens University Belfast, Belfast City Hospital Health and Social Care Trust, Belfast; Victoria Murday, Yorkhill Hospital, Glasgow; John Burn and John C. Mathers, Newcastle University, Newcastle upon Tyne, United Kingdom; Finlay Macrae, Royal Melbourne Hospital, Melbourne, Victoria; Rodney J. Scott, John Hunter Hospital, New Lambton, New South Wales, Australia; Jukka-Pekka Mecklin, Jyväskylä Central Hospital, Jyväskylä, Finland; Gabriela Moeslein, HELIOS St Josefs Hospital, Bochum-Linden, Germany; Sylviane Olschwang, Institut Paoli Calmettes, Marseille, France; Lucio Bertario, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milan, Italy; Marie-Luise Bisgaard, University of Copenhagen, Hvidovre, Denmark; Judy W.C. Ho, Queen Mary Hospital, Hong Kong, Special Administrative Region, People's Republic of China; Annika Lindblom, Karolinska Institutet, Stockholm, Sweden; Jan Lubinski, International Hereditary Cancer Centre, Szczecin, Poland; Raj S. Ramesar, University of Cape Town, South Africa; and Hans F. Vasen, Netherlands Foundation of the Detection of Hereditary Tumours and Leiden University, Leiden, the Netherlands.

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http://dx.doi.org/10.1200/JCO.2014.58.9952DOI Listing
November 2015

Clinical Utility Gene Card for: Familial adenomatous polyposis (FAP) and attenuated FAP (AFAP)--update 2014.

Eur J Hum Genet 2015 Jun 24;23(6). Epub 2014 Sep 24.

INSERM UMR_S 910, Faculté de Médecine La Timone, Marseille, France.

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http://dx.doi.org/10.1038/ejhg.2014.193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795070PMC
June 2015

Known susceptibility SNPs for sporadic prostate cancer show a similar association with "hereditary" prostate cancer.

Prostate 2015 Apr 5;75(5):474-83. Epub 2015 Jan 5.

Department for Health Evidence, Radboud university medical center, Nijmegen, The Netherlands; Department of Urology, Radboud university medical center, Nijmegen, The Netherlands; The Netherlands Foundation for the Detection of Hereditary Tumours, Leiden, The Netherlands.

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http://dx.doi.org/10.1002/pros.22933DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680338PMC
April 2015

Serum peptide signatures for pancreatic cancer based on mass spectrometry: a comparison to CA19-9 levels and routine imaging techniques.

J Cancer Res Clin Oncol 2015 Mar 21;141(3):531-41. Epub 2014 Sep 21.

Department of Surgery, Leiden University Medical Center (LUMC), Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.

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http://dx.doi.org/10.1007/s00432-014-1812-2DOI Listing
March 2015

Lynch syndrome caused by germline PMS2 mutations: delineating the cancer risk.

J Clin Oncol 2015 Feb 15;33(4):319-25. Epub 2014 Dec 15.

Sanne W. ten Broeke, Carli M. Tops, Heleen M. van der Klift, Manon Suerink, Frederik J. Hes, Hans F. Vasen, Maartje Nielsen, and Juul T. Wijnen, Leiden University Medical Center; Hans F. Vasen, The Netherlands Foundation for the Detection of Hereditary Tumors, Leiden; Richard M. Brohet, Research Center Linnaeus Institute, Spaarne Hospital, Hoofddorp; Mary E. Velthuizen and Tom G.W. Letteboer, University Medical Center Utrecht, Utrecht; Encarna Gomez Garcia, Maastricht University Medical Center, Maastricht; Nicoline Hoogerbrugge, Arjen R. Mensenkamp, and Liesbeth Spruijt, Radboud University Medical Center, Nijmegen; Fred H. Menko, Vrije Universiteit, University Medical Center; Theo A. van Os and Bert J.W. Redeker, Academic Medical Center, Amsterdam; Rolf H. Sijmons and Yvonne J. Vos, University of Groningen, University Medical Center Groningen, Groningen; Anja Wagner, Erasmus University Medical Center, Rotterdam, the Netherlands; Inge Bernstein, Aalborg University Hospital, Aalborg; Inge Bernstein, Danish Hereditary Nonpolyposis Colorectal Cancer Registry, Hvidovre University Hospital Copenhagen, Denmark; Gabriel Capellá Munar, Hereditary Cancer Program, Catalan Institute of Oncology-Institut D'Investigació Biomèdica de Bellvitge, l'Hospitalet de Llobregat, Spain; Annika Lindblom, Karolinska Institutet, Karolinska University Hospital, Solna; Pal Moller, Research Group Inherited Cancer, Oslo University Hospital, Oslo, Norway; and Nils Rahner, Institute of Human Genetics, University of Dusseldorf, Dusseldorf, Germany.

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http://dx.doi.org/10.1200/JCO.2014.57.8088DOI Listing
February 2015

Clinical management of hereditary colorectal cancer syndromes.

Nat Rev Gastroenterol Hepatol 2015 Feb 13;12(2):88-97. Epub 2015 Jan 13.

Department of Gastroenterology, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERehd, Villaroel 170, 08036 Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1038/nrgastro.2014.229DOI Listing
February 2015

Quality of colonoscopy in Lynch syndrome.

Endosc Int Open 2014 Dec 24;2(4):E252-5. Epub 2014 Oct 24.

Division of Surgery and of Gastroenterology and Hepatology and Christian Doppler Laboratory on Molecular Cancer Chemoprevention, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1055/s-0034-1377920DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423269PMC
December 2014

Targeted prostate cancer screening in BRCA1 and BRCA2 mutation carriers: results from the initial screening round of the IMPACT study.

Authors:
Elizabeth K Bancroft Elizabeth C Page Elena Castro Hans Lilja Andrew Vickers Daniel Sjoberg Melissa Assel Christopher S Foster Gillian Mitchell Kate Drew Lovise Mæhle Karol Axcrona D Gareth Evans Barbara Bulman Diana Eccles Donna McBride Christi van Asperen Hans Vasen Lambertus A Kiemeney Janneke Ringelberg Cezary Cybulski Dominika Wokolorczyk Christina Selkirk Peter J Hulick Anders Bojesen Anne-Bine Skytte Jimmy Lam Louise Taylor Rogier Oldenburg Ruben Cremers Gerald Verhaegh Wendy A van Zelst-Stams Jan C Oosterwijk Ignacio Blanco Monica Salinas Jackie Cook Derek J Rosario Saundra Buys Tom Conner Margreet G Ausems Kai-ren Ong Jonathan Hoffman Susan Domchek Jacquelyn Powers Manuel R Teixeira Sofia Maia William D Foulkes Nassim Taherian Marielle Ruijs Apollonia T Helderman-van den Enden Louise Izatt Rosemarie Davidson Muriel A Adank Lisa Walker Rita Schmutzler Kathy Tucker Judy Kirk Shirley Hodgson Marion Harris Fiona Douglas Geoffrey J Lindeman Janez Zgajnar Marc Tischkowitz Virginia E Clowes Rachel Susman Teresa Ramón y Cajal Nicholas Patcher Neus Gadea Allan Spigelman Theo van Os Annelie Liljegren Lucy Side Carole Brewer Angela F Brady Alan Donaldson Vigdis Stefansdottir Eitan Friedman Rakefet Chen-Shtoyerman David J Amor Lucia Copakova Julian Barwell Veda N Giri Vedang Murthy Nicola Nicolai Soo-Hwang Teo Lynn Greenhalgh Sara Strom Alex Henderson John McGrath David Gallagher Neil Aaronson Audrey Ardern-Jones Chris Bangma David Dearnaley Philandra Costello Jorunn Eyfjord Jeanette Rothwell Alison Falconer Henrik Gronberg Freddie C Hamdy Oskar Johannsson Vincent Khoo Zsofia Kote-Jarai Jan Lubinski Ulrika Axcrona Jane Melia Joanne McKinley Anita V Mitra Clare Moynihan Gad Rennert Mohnish Suri Penny Wilson Emma Killick Sue Moss Rosalind A Eeles

Eur Urol 2014 Sep 15;66(3):489-99. Epub 2014 Jan 15.

Oncogenetics Team, Institute of Cancer Research, London, UK; Cancer Genetics Unit and Academic Urology Unit, Royal Marsden NHS Foundation Trust, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2014.01.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105321PMC
September 2014

A pooled analysis of the outcome of prospective colonoscopic surveillance for familial colorectal cancer.

Int J Cancer 2014 Feb 29;134(4):939-47. Epub 2013 Aug 29.

Queen Mary University of London, Centre for Cancer Prevention, Wolfson Institute of Preventive Medicine, Charterhouse Square, London, United Kingdom.

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http://dx.doi.org/10.1002/ijc.28397DOI Listing
February 2014

Extracolonic cancer risk in patients with serrated polyposis syndrome and their first-degree relatives.

Fam Cancer 2013 Dec;12(4):669-73

Department of Gastroenterology and Hepatology, Academic Medical Centre, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands,

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http://dx.doi.org/10.1007/s10689-013-9643-xDOI Listing
December 2013

Reply to Win and Jenkins.

Int J Cancer 2013 Oct 18;133(7):1764. Epub 2013 Apr 18.

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http://dx.doi.org/10.1002/ijc.28178DOI Listing
October 2013

Surveillance of second-degree relatives from melanoma families with a CDKN2A germline mutation.

Cancer Epidemiol Biomarkers Prev 2013 Oct 29;22(10):1771-7. Epub 2013 Jul 29.

Authors' Affiliations: Department of Dermatology, Medical Statistics and Clinical Epidemiology, Clinical Genetics, Leiden University Medical Center, Leiden; Medical Affairs, Agendia, Amsterdam; Department of Pathology, VU University Medical Center, Amsterdam; The Netherlands Foundation for the Detection of Hereditary Tumors, Leiden; and Department of Gastroenterology, Leiden University Medical Center, Leiden, the Netherlands.

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http://dx.doi.org/10.1158/1055-9965.EPI-13-0130DOI Listing
October 2013

Do lifestyle factors influence colorectal cancer risk in Lynch syndrome?

Fam Cancer 2013 Jun;12(2):285-93

Division of Human Nutrition, Wageningen University, Wageningen, The Netherlands.

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http://dx.doi.org/10.1007/s10689-013-9645-8DOI Listing
June 2013

A hundred years of Lynch syndrome research (1913-2013).

Fam Cancer 2013 Jun;12(2):141-2

Department of Gastroenterology & Hepatology, Leiden University Medical Centre, Leiden, The Netherlands.

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http://dx.doi.org/10.1007/s10689-013-9654-7DOI Listing
June 2013

Reply to V. Bonadona et al.

J Clin Oncol 2013 Jun;31(17):2230

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http://dx.doi.org/10.1200/JCO.2013.49.0433DOI Listing
June 2013

Dietary patterns and colorectal adenomas in Lynch syndrome: the GEOLynch cohort study.

Cancer 2013 Feb 17;119(3):512-21. Epub 2012 Dec 17.

Division of Human Nutrition, Wageningen University, Wageningen, the Netherlands.

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http://doi.wiley.com/10.1002/cncr.27726
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http://dx.doi.org/10.1002/cncr.27726DOI Listing
February 2013

Variation in precursor lesions of pancreatic cancer among high-risk groups.

Clin Cancer Res 2013 Jan 21;19(2):442-9. Epub 2012 Nov 21.

Departments of Gastroenterology & Hepatology, Radiology, Pathology, and Surgery, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1158/1078-0432.CCR-12-2730DOI Listing
January 2013

Ovarian metastases of colorectal and duodenal cancer in familial adenomatous polyposis.

Fam Cancer 2012 Dec;11(4):671-3

Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1007/s10689-012-9565-zDOI Listing
December 2012

Surveillance for hereditary cancer: does the benefit outweigh the psychological burden?--A systematic review.

Crit Rev Oncol Hematol 2012 Sep 25;83(3):329-40. Epub 2012 Feb 25.

Centre for Human and Clinical Genetics, Leiden University Medical Centre, Leiden, The Netherlands.

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http://linkinghub.elsevier.com/retrieve/pii/S104084281200017
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http://dx.doi.org/10.1016/j.critrevonc.2012.01.004DOI Listing
September 2012