Hans Spiegel

Hans Spiegel

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Hans Spiegel

Hans Spiegel

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Failure to thrive: Case definition & guidelines for data collection, analysis, and presentation of maternal immunisation safety data.

Vaccine 2017 12;35(48 Pt A):6483-6491

Monash University, Department of Paediatrics, Infection and Immunity, Monash Children's Hospital, Monash Health; SAEFVIC, Murdoch Children's Research Institute, Melbourne, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2017.01.051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714432PMC
December 2017

HIV birth testing and linkage to care for HIV-infected infants.

AIDS 2017 08;31(13):1797-1807

aNational Institute of Allergy and Infectious Diseases, National Institutes of Health bKelly Government Solutions cColumbus Technologies and Services Inc., Contractor to the National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA dWHO, Geneva, Switzerland eChildren Hospital of Los Angeles, Los Angeles, California, USA fStellenbosh University, Cape Town, South Africa gColumbia University Mailman School of Public Health, New York City, New York, USA.

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http://dx.doi.org/10.1097/QAD.0000000000001561DOI Listing
August 2017

The interaction between equipoise and logistics in clinical trials: A case study.

Clin Trials 2017 Jun 31;14(3):314-318. Epub 2017 Jan 31.

10 Division of Pediatric Infectious Diseases, Department of Pediatrics, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.

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http://dx.doi.org/10.1177/1740774517690734DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446272PMC
June 2017

The interaction between equipoise and logistics in clinical trials: A case study.

Clin Trials 2017 Jun 31;14(3):314-318. Epub 2017 Jan 31.

10 Division of Pediatric Infectious Diseases, Department of Pediatrics, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.

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http://dx.doi.org/10.1177/1740774517690734DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446272PMC
June 2017

Comparison of Dapivirine Vaginal Gel and Film Formulation Pharmacokinetics and Pharmacodynamics (FAME 02B).

AIDS Res Hum Retroviruses 2017 04 13;33(4):339-346. Epub 2016 Dec 13.

3 Department of Medicine (Clinical Pharmacology), Johns Hopkins University , Baltimore, Maryland.

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http://dx.doi.org/10.1089/AID.2016.0040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372771PMC
April 2017

Safety and Efficacy of Atorvastatin in Human Immunodeficiency Virus-infected Children, Adolescents and Young Adults With Hyperlipidemia.

Pediatr Infect Dis J 2017 01;36(1):53-60

From the *Division of Pediatric Infectious Disease, Department of Pediatrics, University of Washington and Seattle Children's Research Institute, Seattle, Washington; †Center for Biostatistics in AIDS Research, Harvard School of Public Health, Boston, Massachusetts; ‡Quest Diagnostics, Baltimore, Maryland; §HJF-DAIDS, a Division of The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc, Contractor to National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland; ¶Department of Pediatrics, New York University School of Medicine, New York City, New York; ‖Department of Pediatrics (Infectious Diseases), University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, Colorado; **UC San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences and School of Medicine, University of California San Diego, San Diego, California; ††Department of Pediatrics and Microbiology, University of Alabama at Birmingham Pediatric Infectious Diseases, Birmingham, Alabama; ‡‡Department of Food Science and Human Nutrition, University of Florida, Gainesville, Florida; §§Frontier Science Inc., Buffalo, New York; ¶¶University of Southern California Maternal Child Adolescent Virology Research Lab, Los Angeles, California; ‖‖Pharmaceutical Affairs Branch Division of AIDS, NIAID, NIH, Bethesda, Maryland; and ***Maternal and Pediatric Infectious Disease Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1097/INF.0000000000001352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154931PMC
January 2017

Cost-Effectiveness of Pre-exposure HIV Prophylaxis During Pregnancy and Breastfeeding in Sub-Saharan Africa.

J Acquir Immune Defic Syndr 2016 08;72 Suppl 2:S145-53

*Division of Global Women's Health, Department of Obstetrics and Gynecology, University of North Carolina Chapel Hill, Chapel Hill, NC; †Department of Health Policy and Management, University of North Carolina at Chapel Hill, Chapel Hill, NC; ‡Department of Pediatrics and Child Health, College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe; §Department of Psychiatry, John Stroger Hospital of Cook County, Chicago, IL; ‖Office of the Global AIDS Coordinator and Health Diplomacy, U.S. Department of State, Washington, DC; ¶Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD; and #Kelly Government Services, Contractor to Prevention Sciences Program, Division of AIDS, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043081PMC
http://dx.doi.org/10.1097/QAI.0000000000001063DOI Listing
August 2016

A Phase 1 Trial to Assess the Safety, Acceptability, Pharmacokinetics, and Pharmacodynamics of a Novel Dapivirine Vaginal Film.

J Acquir Immune Defic Syndr 2016 Apr;71(5):498-505

*Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh, Pittsburgh, PA; †Magee-Womens Research Institute, Pittsburgh, PA; ‡Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA; §Division of Clinical Pharmacology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD; ‖Alpha StatConsult, Damascus, MD; ¶International Partnership for Microbicides, Silver Spring, MD; and #HJF-DAIDS, a Division of The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Contractor to National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Services, Rockville, MD.

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http://pdfs.journals.lww.com/jaids/2016/04150/A_Phase_1_Tria
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/QAI.0000000000000897DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040830PMC
April 2016

A Phase 1 Trial to Assess the Safety, Acceptability, Pharmacokinetics, and Pharmacodynamics of a Novel Dapivirine Vaginal Film.

J Acquir Immune Defic Syndr 2016 Apr;71(5):498-505

*Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh, Pittsburgh, PA; †Magee-Womens Research Institute, Pittsburgh, PA; ‡Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA; §Division of Clinical Pharmacology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD; ‖Alpha StatConsult, Damascus, MD; ¶International Partnership for Microbicides, Silver Spring, MD; and #HJF-DAIDS, a Division of The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Contractor to National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Services, Rockville, MD.

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http://pdfs.journals.lww.com/jaids/2016/04150/A_Phase_1_Tria
Web Search
http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
Publisher Site
http://dx.doi.org/10.1097/QAI.0000000000000897DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040830PMC
April 2016

Feasibility of radiolabeled small molecule permeability as a quantitative measure of microbicide candidate toxicity.

Contraception 2016 Apr 6;93(4):331-336. Epub 2016 Jan 6.

Johns Hopkins University School of Medicine Division of Clinical Pharmacology, Department of Medicine.

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http://dx.doi.org/10.1016/j.contraception.2016.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783221PMC
April 2016

A Blueprint to Address Research Gaps in the Development of Biomarkers for Pediatric Tuberculosis.

Clin Infect Dis 2015 Oct;61Suppl 3:S164-72

Department of Science and Technology and National Research Foundation Centre of Excellence for Biomedical Tuberculosis Research/Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa.

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http://dx.doi.org/10.1093/cid/civ613DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583573PMC
October 2015

A Blueprint to Address Research Gaps in the Development of Biomarkers for Pediatric Tuberculosis.

Clin Infect Dis 2015 Oct;61Suppl 3:S164-72

Department of Science and Technology and National Research Foundation Centre of Excellence for Biomedical Tuberculosis Research/Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa.

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http://dx.doi.org/10.1093/cid/civ613DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583573PMC
October 2015

Predictors of resolution and persistence of renal laboratory abnormalities in pediatric HIV infection.

Pediatr Nephrol 2015 Jan 24;30(1):153-65. Epub 2014 Aug 24.

Division of Infectious Diseases and Immunology, Department of Pediatrics, University of Miami Miller School of Medicine, Room 286, Batchelor Children's Research Institute, 1580 NW 10th Avenue, Miami, 33136, FL, USA,

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http://dx.doi.org/10.1007/s00467-014-2909-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301405PMC
January 2015

Critical need for appropriate mucosal sample collection to determine relational animal pharmacokinetic-pharmacodynamic models in HIV prevention.

AIDS Res Hum Retroviruses 2013 Nov 30;29(11):1398-400. Epub 2013 Aug 30.

1 Preclinical Microbicide and Prevention Research Branch, Prevention Sciences Program, Division of AIDS, National Institute of Allergy and Infectious Disease, National Institutes of Health , Bethesda, Maryland.

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http://dx.doi.org/10.1089/AID.2013.0142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3809943PMC
November 2013

Chronic kidney disease associated with perinatal HIV infection in children and adolescents.

Pediatr Nephrol 2012 Jun 26;27(6):981-9. Epub 2012 Feb 26.

Department of Pediatrics, Bronx-Lebanon Hospital Center, Albert Einstein College of Medicine, Bronx, NY 10457, USA.

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http://dx.doi.org/10.1007/s00467-011-2097-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715373PMC
June 2012

Prevalence of congenital anomalies in infants with in utero exposure to antiretrovirals.

Pediatr Infect Dis J 2012 Feb;31(2):164-70

Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN 38105–3678, USA.

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http://dx.doi.org/10.1097/INF.0b013e318235c7aaDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261302PMC
February 2012

Nondisclosure of HIV status in adolescence.

Authors:
Hans M L Spiegel

Adolesc Med State Art Rev 2011 Aug;22(2):277-82, x

Henry M. Jackson Foundation for the Advancement of Military Medicine, Medical Officer, Microbicide Research Branch, Prevention Sciences Program, DAIDS, NIAID, National Institutes of Health, 6700A Rockledge Drive, Suite 200, Room 42A 123, Bethesda, Maryland 20817, USA.

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August 2011

Informing Adolescents of Perinatally Contracted HIV.

Virtual Mentor 2009 Dec 1;11(12):938-43. Epub 2009 Dec 1.

Children's Hospital at Montefiore in the Bronx, New York.

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http://dx.doi.org/10.1001/virtualmentor.2009.11.12.ccas2-0912DOI Listing
December 2009

Human parechovirus-3 infection: emerging pathogen in neonatal sepsis.

Pediatr Infect Dis J 2009 Jun;28(6):545-7

Division of Infectious Diseases, Children's National Medical Center, Washington, DC, USA.

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http://dx.doi.org/10.1097/INF.0b013e318194596aDOI Listing
June 2009

Adolescents and HIV: prevention and clinical care.

Curr HIV/AIDS Rep 2009 May;6(2):100-7

Albert Einstein College of Medicine, Adolescent AIDS Program, Montefiore Medical Center, Bronx, NY 10467, USA.

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http://dx.doi.org/10.1007/s11904-009-0015-yDOI Listing
May 2009

Epidemiology of new cases of HIV-1 infection in children referred to the metropolitan pediatric hospital in Washington, DC.

Pediatr Infect Dis J 2008 Sep;27(9):837-9

Division of Infectious Disease, The George Washington University School of Medicine and Health Sciences, Washington, DC 20010, USA.

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http://dx.doi.org/10.1097/INF.0b013e3181719fa5DOI Listing
September 2008

Nevirapine concentration in nonstimulated saliva: an alternative to plasma sampling in children with human immunodeficiency virus infection.

Ther Drug Monit 2007 Feb;29(1):110-7

Division of Infectious Disease, The George Washington University School of Medicine, Washington, DC 20010, USA.

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http://dx.doi.org/10.1097/FTD.0b013e31803258edDOI Listing
February 2007

Sampling of major histocompatibility complex class I-associated peptidome suggests relatively looser global association of HLA-B*5101 with peptides.

Hum Immunol 2006 Nov 20;67(11):894-906. Epub 2006 Sep 20.

Center for Cancer and Immunology Research, Children's Research Institute, Children's National Medical Center, Washington, DC 20010-2970, USA.

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http://dx.doi.org/10.1016/j.humimm.2006.08.294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2269730PMC
November 2006

Meningoencephalitis in a child complicated by myocarditis, quadriparesis and respiratory failure.

Pediatr Infect Dis J 2006 Sep;25(9):853, 855-6

Department of Infectious Disease, Children's National Medical Center, Bethesda, MD, USA.

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http://dx.doi.org/10.1097/01.inf.0000234058.31683.70DOI Listing
September 2006

Microsurgical training curriculum for learning kidney and liver transplantation in the rat.

Microsurgery 2005 ;25(8):614-23

Section of Surgical Research, Department of General Surgery, Münster University Hospital, Münster, Germany.

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http://dx.doi.org/10.1002/micr.20174DOI Listing
March 2006

Therapeutic drug monitoring for patients with HIV infection: Children's National Medical Center, Washington DC experience.

Ther Drug Monit 2004 Apr;26(2):107-9

Department of Pediatrics, The George Washington University School of Medicine, Washington, DC, USA.

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http://dx.doi.org/10.1097/00007691-200404000-00003DOI Listing
April 2004