Hans Lehrach

Hans Lehrach

UNVERIFIED PROFILE

Are you Hans Lehrach?   Register this Author

Register author
Hans Lehrach

Hans Lehrach

Publications by authors named "Hans Lehrach"

Are you Hans Lehrach?   Register this Author

100Publications

2958Reads

50Profile Views

Efficient Parameter Estimation Enables the Prediction of Drug Response Using a Mechanistic Pan-Cancer Pathway Model.

Cell Syst 2018 12 28;7(6):567-579.e6. Epub 2018 Nov 28.

Institute of Computational Biology, Helmholtz Zentrum München, Neuherberg 85764, Germany; Center for Mathematics, Chair of Mathematical Modeling of Biological Systems, Technische Universität München, Garching 85748, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cels.2018.10.013DOI Listing
December 2018

Metabolomics in Sepsis and Its Impact on Public Health.

Public Health Genomics 2017 19;20(5):274-285. Epub 2018 Jan 19.

UNU-MERIT (Maastricht Economic and Social Research Institute on Innovation and Technology), Maastricht University, Maastricht, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000486362DOI Listing
November 2018

Cancer Precision Medicine: Why More Is More and DNA Is Not Enough.

Public Health Genomics 2017 9;20(2):70-80. Epub 2017 Jun 9.

Alacris Theranostics GmbH, Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000477157DOI Listing
April 2018

Simple paired heavy- and light-chain antibody repertoire sequencing using endoplasmic reticulum microsomes.

Genome Med 2018 04 27;10(1):34. Epub 2018 Apr 27.

Otto Warburg Laboratory Gene Regulation and Systems Biology of Cancer, Max Planck Institute for Molecular Genetics, Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13073-018-0542-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921987PMC
April 2018

Multi-Omics Research Trends in Sepsis: A Bibliometric, Comparative Analysis Between the United States, the European Union 28 Member States, and China.

OMICS 2018 03;22(3):190-197

1 Maastricht Economic and Social Research Institute on Innovation and Technology (MERIT), Maastricht University , Maastricht, The Netherlands .

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/omi.2017.0192DOI Listing
March 2018

The intron-enriched HERV-K(HML-10) family suppresses apoptosis, an indicator of malignant transformation.

Mob DNA 2016 7;7:25. Epub 2016 Dec 7.

Max Planck Institute for molecular Genetics, Ihnestr. 63-73, 14195 Berlin, Germany ; Institute of Medical Microbiology, University of Zurich, Gloriastr. 32, 8006 Zurich, Switzerland.

View Article

Download full-text PDF

Source
http://mobilednajournal.biomedcentral.com/articles/10.1186/s
Publisher Site
http://dx.doi.org/10.1186/s13100-016-0081-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142424PMC
December 2016

Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells.

Cell 2016 11;167(5):1398-1414.e24

Department of Human Genetics, The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1HH, UK; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Long Road, Cambridge CB2 0PT, UK; British Heart Foundation Centre of Excellence, Division of Cardiovascular Medicine, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0QQ, UK; The National Institute for Health Research Blood and Transplant Unit (NIHR BTRU) in Donor Health and Genomics at the University of Cambridge, Strangeways Research Laboratory, University of Cambridge, Wort's Causeway, Cambridge CB1 8RN, UK. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00928674163144
Publisher Site
http://dx.doi.org/10.1016/j.cell.2016.10.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119954PMC
November 2016

Virtual Clinical Trials, an Essential Step in Increasing the Effectiveness of the Drug Development Process.

Authors:
Hans Lehrach

Public Health Genomics 2015 5;18(6):366-71. Epub 2015 Nov 5.

Max Planck Institute for Molecular Genetics (MPIMG), Dahlem Centre for Genome Research and Medical Systems Biology (DCGMS), and Alacris Theranostics GmbH, Berlin, Germany.

View Article

Download full-text PDF

Source
https://www.karger.com/Article/FullText/441553
Publisher Site
http://dx.doi.org/10.1159/000441553DOI Listing
October 2016

Omics approaches to individual variation: modeling networks and the virtual patient.

Authors:
Hans Lehrach

Dialogues Clin Neurosci 2016 09;18(3):253-265

Max Planck Institute for Molecular Genetics (MPIMG), Berlin, Germany; Dahlem Centre for Genome Research and Medical Systems Biology (DCGMS), Berlin, Germany; French National Institute of Health and Medical Research (INSERM), US13, Paris, France; Alacris Theranostics GmbH, Berlin, Germany.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067143PMC
September 2016

Combined sequencing of mRNA and DNA from human embryonic stem cells.

Genom Data 2016 Jun 26;8:131-3. Epub 2016 Apr 26.

Institute for Stem Cell Research and Regenerative Medicine, Heinrich Heine University, Moorenstr. 5, 40225 Düsseldorf, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.gdata.2016.04.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880790PMC
June 2016

Human Lineage-Specific Transcriptional Regulation through GA-Binding Protein Transcription Factor Alpha (GABPa).

Mol Biol Evol 2016 05 26;33(5):1231-44. Epub 2016 Jan 26.

Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Berlin, Germany

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/molbev/msw007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839217PMC
May 2016

Predictive Modeling of Drug Treatment in the Area of Personalized Medicine.

Cancer Inform 2015 6;14(Suppl 4):95-103. Epub 2015 Dec 6.

Alacris Theranostics GmbH, Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4137/CIN.S1933DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671548PMC
December 2015

The direction of cross affects [corrected] obesity after puberty in male but not female offspring.

BMC Genomics 2015 Nov 6;16:904. Epub 2015 Nov 6.

Albrecht Daniel Thaer-Institut für Agrar- und Gartenbauwissenschaften, Humboldt-Universität zu Berlin, Invalidenstraße 42, D-10115, Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12864-015-2164-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636810PMC
November 2015

Combined ultra-low input mRNA and whole-genome sequencing of human embryonic stem cells.

BMC Genomics 2015 Nov 12;16:925. Epub 2015 Nov 12.

Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Ihnestr. 63-73, 14195, Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12864-015-2025-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643517PMC
November 2015

Erratum to: 'The direction of cross affects obesity after puberty in male but not female offspring'.

BMC Genomics 2015 Nov 30;16(1):1018. Epub 2015 Nov 30.

Albrecht Daniel Thaer-Institut für Agrar- und Gartenbauwissenschaften, Humboldt-Universität zu Berlin, Invalidenstraße 42, Berlin, D-10115, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12864-015-2204-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665910PMC
November 2015

Exome sequencing from nanogram amounts of starting DNA: comparing three approaches.

PLoS One 2014 3;9(7):e101154. Epub 2014 Jul 3.

Max-Planck Institute for Molecular Genetics, Berlin, Germany; AlacrisTheranostics GmbH, Berlin, Germany.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0101154PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081514PMC
October 2015

Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options.

Nat Genet 2015 Sep 27;47(9):1020-1029. Epub 2015 Jul 27.

Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.3362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603357PMC
September 2015

Network and systems biology: essential steps in virtualising drug discovery and development.

Drug Discov Today Technol 2015 Aug 8;15:33-40. Epub 2015 Aug 8.

Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Berlin, Germany; Dahlem Centre for Genome Research and Medical Systems Biology, Berlin, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ddtec.2015.07.002DOI Listing
August 2015

The nerve growth factor receptor CD271 is crucial to maintain tumorigenicity and stem-like properties of melanoma cells.

PLoS One 2014 5;9(5):e92596. Epub 2014 May 5.

Institute of Pathology - University Hospital Berlin, Berlin, Germany; Laboratory of Functional Genomics (LFGC) - University Hospital Berlin, Berlin, Germany; Comprehensive Cancer Center Charité - University Hospital Berlin, Berlin, Germany.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0092596PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010406PMC
June 2015

Temporary loss of moral behavior in a patient undergoing chemotherapy with cisplatin - breaking bad.

BMC Psychiatry 2015 Feb 5;15. Epub 2015 Feb 5.

Department of Psychiatry and Psychotherapy, Dresden-Friedrichstadt Municipal Hospital, Dresden, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12888-015-0386-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321323PMC
February 2015

Multiple haplotype-resolved genomes reveal population patterns of gene and protein diplotypes.

Nat Commun 2014 Nov 26;5:5569. Epub 2014 Nov 26.

1] Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Berlin D-14195, Germany [2].

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncomms6569DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263165PMC
November 2014

ARH-seq: identification of differential splicing in RNA-seq data.

Nucleic Acids Res 2014 Aug 11;42(14):e110. Epub 2014 Jun 11.

Max-Planck-Institute for Molecular Genetics, Department of Vertebrate Genomics, Ihnestrasse 63-73, 14195 Berlin, Germany

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gku495DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132698PMC
August 2014

5-Fluorouracil affects assembly of stress granules based on RNA incorporation.

Nucleic Acids Res 2014 Jun 11;42(10):6436-47. Epub 2014 Apr 11.

Otto Warburg Laboratory, Max Planck Institute for Molecular Genetics, 14195 Berlin, Germany

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gku264DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041438PMC
June 2014

Future of medicine: models in predictive diagnostics and personalized medicine.

Adv Biochem Eng Biotechnol 2013 ;133:15-33

Fraunhofer Institute for Biomedical Engineering, Am Mühlenberg 13, 14476, Potsdam, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/10_2012_176DOI Listing
May 2014

Parallel profiling of the transcriptome, cistrome, and epigenome in the cellular response to ionizing radiation.

Sci Signal 2014 May 13;7(325):rs3. Epub 2014 May 13.

The David and Inez Myers Laboratory for Cancer Research, Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/scisignal.2005032DOI Listing
May 2014

The genome of the recently domesticated crop plant sugar beet (Beta vulgaris).

Nature 2014 Jan 18;505(7484):546-9. Epub 2013 Dec 18.

1] Max Planck Institute for Molecular Genetics, Ihnestraße 63-73, 14195 Berlin, Germany [2] Centre for Genomic Regulation (CRG), C. Dr. Aiguader 88, 08003 Barcelona, Spain [3] Universitat Pompeu Fabra (UPF), C. Dr. Aiguader 88, 08003 Barcelona, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature12817DOI Listing
January 2014

BMP10 as a potent inducer of trophoblast differentiation in human embryonic and induced pluripotent stem cells.

Biomaterials 2013 Dec 23;34(38):9789-802. Epub 2013 Sep 23.

Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Ihnestr. 63-73, 14195 Berlin, Germany; Department of Biology, Chemistry and Pharmacy, Institute of Chemistry and Biochemistry, Freie Universität Berlin, Thielallee 63, 14195 Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.biomaterials.2013.08.084DOI Listing
December 2013

ERG induces epigenetic activation of Tudor domain-containing protein 1 (TDRD1) in ERG rearrangement-positive prostate cancer.

PLoS One 2013 29;8(3):e59976. Epub 2013 Mar 29.

Unit Cancer Genome Research, Division of Molecular Genetics, National Center for Tumor Diseases (NCT) and German Cancer Research Center (DKFZ), Heidelberg, Germany.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0059976PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612037PMC
September 2013

DNA sequencing methods in human genetics and disease research.

Authors:
Hans Lehrach

F1000Prime Rep 2013 Sep 2;5:34. Epub 2013 Sep 2.

Max Planck Institute for Molecular Genetics Ihnestrasse 73, 14195, Berlin Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.12703/P5-34DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3768324PMC
September 2013

Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma.

Nat Genet 2013 Aug 30;45(8):927-32. Epub 2013 Jun 30.

Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.

View Article

Download full-text PDF

Source
http://pubman.mpdl.mpg.de/pubman/item/escidoc:1982973/compon
Web Search
http://www.nature.com/doifinder/10.1038/ng.2682
Publisher Site
http://dx.doi.org/10.1038/ng.2682DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951336PMC
August 2013

Genomics and epigenomics of colorectal cancer.

Wiley Interdiscip Rev Syst Biol Med 2013 Mar-Apr;5(2):205-19. Epub 2013 Jan 16.

Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/wsbm.1206DOI Listing
July 2013

Janus--a comprehensive tool investigating the two faces of transcription.

Bioinformatics 2013 Jul 24;29(13):1600-6. Epub 2013 Apr 24.

Institute for Clinical Molecular Biology, Christian-Albrechts-University, 24105 Kiel, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bioinformatics/btt185DOI Listing
July 2013

Fkh1 and Fkh2 associate with Sir2 to control CLB2 transcription under normal and oxidative stress conditions.

Front Physiol 2013 12;4:173. Epub 2013 Jul 12.

Otto Warburg Laboratory, Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics Berlin, Germany ; Department of Biology, Chemistry and Pharmacy, Free University Berlin Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fphys.2013.00173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709100PMC
July 2013

Ataxin-2-like is a regulator of stress granules and processing bodies.

PLoS One 2012 27;7(11):e50134. Epub 2012 Nov 27.

Otto Warburg Laboratory, Max Planck Institute for Molecular Genetics, Berlin, Germany.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0050134PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507954PMC
June 2013

IT Future of Medicine: from molecular analysis to clinical diagnosis and improved treatment.

N Biotechnol 2013 May 16;30(4):362-5. Epub 2012 Nov 16.

Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73, 14195 Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nbt.2012.11.002DOI Listing
May 2013

Optimal precursor ion selection for LC-MALDI MS/MS.

BMC Bioinformatics 2013 Feb 18;14:56. Epub 2013 Feb 18.

Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2105-14-56DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651328PMC
February 2013

The ConsensusPathDB interaction database: 2013 update.

Nucleic Acids Res 2013 Jan 11;41(Database issue):D793-800. Epub 2012 Nov 11.

Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73, 14195 Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gks1055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531102PMC
January 2013

RNA-Seq provides new insights in the transcriptome responses induced by the carcinogen benzo[a]pyrene.

Toxicol Sci 2012 Dec 13;130(2):427-39. Epub 2012 Aug 13.

Department of Toxicogenomics, Maastricht University, Maastricht, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/toxsci/kfs250DOI Listing
December 2012

FGF inhibition directs BMP4-mediated differentiation of human embryonic stem cells to syncytiotrophoblast.

Stem Cells Dev 2012 Nov 6;21(16):2987-3000. Epub 2012 Aug 6.

Department of Vertebrate Genomics, Molecular Embryology and Aging Group, Max Planck Institute for Molecular Genetics, Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/scd.2012.0099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475151PMC
November 2012

Prediction in the face of uncertainty: a Monte Carlo-based approach for systems biology of cancer treatment.

Mutat Res 2012 Aug 23;746(2):163-70. Epub 2012 Jan 23.

Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73, 14195 Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.mrgentox.2012.01.005DOI Listing
August 2012

Dissecting the genomic complexity underlying medulloblastoma.

Nature 2012 Aug;488(7409):100-5

Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, Heidelberg 69120, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature11284DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662966PMC
August 2012

T cells become licensed in the lung to enter the central nervous system.

Nature 2012 Aug;488(7413):675-9

Institute for Multiple Sclerosis Research, Department of Neuroimmunology, Gemeinnützige Hertie-Stiftung and University Medical Centre Göttingen, 37073 Göttingen, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature11337DOI Listing
August 2012

Sic1 plays a role in timing and oscillatory behaviour of B-type cyclins.

Biotechnol Adv 2012 Jan-Feb;30(1):108-30. Epub 2011 Sep 18.

Institute for Biology, Theoretical Biophysics, Humboldt University Berlin, Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.biotechadv.2011.09.004DOI Listing
July 2012

The cytotoxic and immunogenic hurdles associated with non-viral mRNA-mediated reprogramming of human fibroblasts.

Biomaterials 2012 Jun 28;33(16):4059-68. Epub 2012 Feb 28.

Molecular Embryology and Aging Group, Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Ihnestr. 63-73, 14195 Berlin, Germany.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S01429612120020
Publisher Site
http://dx.doi.org/10.1016/j.biomaterials.2012.02.025DOI Listing
June 2012

A simple strand-specific RNA-Seq library preparation protocol combining the Illumina TruSeq RNA and the dUTP methods.

Biochem Biophys Res Commun 2012 Jun 15;422(4):643-6. Epub 2012 May 15.

Max Planck Institute for Molecular Genetics, Ihnestr. 73, D-14195 Berlin, Germany.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S0006291X1200920
Publisher Site
http://dx.doi.org/10.1016/j.bbrc.2012.05.043DOI Listing
June 2012

Creation and application of immortalized bait libraries for targeted enrichment and next-generation sequencing.

Biotechniques 2012 Jun;52(6):375-80

Max Planck Institute for Molecular Genetics, Ihnestrasse 73, 14195 Berlin, Germany.

View Article

Download full-text PDF

Source
https://www.future-science.com/doi/10.2144/0000113877
Publisher Site
http://dx.doi.org/10.2144/0000113877DOI Listing
June 2012

Modeling of miRNA and drug action in the EGFR signaling pathway.

PLoS One 2012 11;7(1):e30140. Epub 2012 Jan 11.

Department Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Berlin, Germany.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0030140PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256223PMC
May 2012

DIPSBC--data integration platform for systems biology collaborations.

BMC Bioinformatics 2012 May 8;13:85. Epub 2012 May 8.

Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Ihnestr. 63-73, 14195 Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2105-13-85DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424966PMC
May 2012

A revolution in healthcare: challenges and opportunities for personalized medicine.

Authors:
Hans Lehrach

Per Med 2012 Mar;9(2):105-108

Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73, 14195 Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/pme.12.9DOI Listing
March 2012

Public health perspective: from personalized medicine to personal health.

Per Med 2012 Mar;9(2):115-119

Institute for Public Health Genomics, Maastricht University, Universiteitssingel 40, 6229 ER, Maastricht, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/pme.12.16DOI Listing
March 2012

Pushing the detection limits: the evanescent field in surface plasmon resonance and analyte-induced folding observation of long human telomeric repeats.

Biosens Bioelectron 2012 Jan 10;31(1):571-4. Epub 2011 Nov 10.

Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73, 14195 Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bios.2011.11.003DOI Listing
January 2012

Targeted enrichment of genomic DNA regions for next-generation sequencing.

Brief Funct Genomics 2011 Nov 26;10(6):374-86. Epub 2011 Nov 26.

Max Planck Institute for Molecular Genetics, Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bfgp/elr033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245553PMC
November 2011

Methylation-specific ligation detection reaction (msLDR): a new approach for multiplex evaluation of methylation patterns.

Mol Genet Genomics 2011 Oct 31;286(3-4):279-91. Epub 2011 Aug 31.

Institute of Pathology, University Medicine Charité, Charitéplatz1, 10117 Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00438-011-0645-9DOI Listing
October 2011