Publications by authors named "Hans K Schackert"

93Publications

Correction: Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database.

Genet Med 2020 Sep;22(9):1569

Department of Tumor Biology, Institute of Cancer Research, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway.

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http://dx.doi.org/10.1038/s41436-020-0892-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462742PMC
September 2020

Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database.

Genet Med 2020 01 24;22(1):15-25. Epub 2019 Jul 24.

Department of Tumor Biology, Institute of Cancer Research, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway.

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http://dx.doi.org/10.1038/s41436-019-0596-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371626PMC
January 2020

Cancer Risks for PMS2-Associated Lynch Syndrome.

J Clin Oncol 2018 10 30;36(29):2961-2968. Epub 2018 Aug 30.

Sanne W. ten Broeke, Heleen M. van der Klift, Carli M.J. Tops, Manon Suerink, Frederik J. Hes, Hans F.A. Vasen, Juul T. Wijnen, and Maartje Nielsen, Leiden University Medical Center, Leiden; Encarna Gomez Garcia, Maastricht University Medical Center, Maastricht; Nicoline Hoogerbrugge, Arjen R. Mensenkamp, and Liesbeth Spruijt, Radboud University Medical Center, Nijmegen; Tom G.W. Letteboer, University Medical Center, Utrecht; Theo A.M. van Os and Egbert J.W. Redeker, Academic Medical Center, Amsterdam; Maran J.W. Olderode-Berends and Yvonne J. Vos, University of Groningen; University Medical Center Groningen, Groningen; Anja Wagner, Erasmus Medical Center, Rotterdam, the Netherlands; Stefan Aretz, University of Bonn; University Hospital Bonn, Bonn; Christoph Engel, Leipzig University; Medizinisch Genetisches Zentrum Bayerstr, Leipzig; Magnus von Knebel Doeberitz, University of Heidelberg; German Cancer Research Center, Heidelberg; Pål Møller, University of Witten-Herdecke, Wuppertal; Nils Rahner, Heinrich-Heine-University, Düsseldorf; Hans K. Schackert, Technische Universität Dresden, Dresden; Verena Steinke-Lange, Medizinische Klinik und Poliklinik IV Campus Innenstadt, Klinikum der Universität München, Munich, Germany; Pål Møller, The Norwegian Radium Hospital; Oslo University Hospital, Oslo, Norway; Inge Bernstein, Hvidovre Hospital, Hvidovre, and Aalborg University Hospital, Aalborg, Denmark; Daniel D. Buchanan, Mark Clendenning, John L. Hopper, Mark A. Jenkins, Christophe Rosty, Ingrid Winship, and Aung Ko Win, The University of Melbourne; Daniel D. Buchanan, Ingrid Winship, and Aung Ko Win, Royal Melbourne Hospital, Parkville, Melbourne, Victoria; Rodney Scott, University of Newcastle, Newcastle, New South Wales, Australia; Albert de la Chapelle, Heather L. Hampel, Rachel Pearlman, and Leigha Senter, The Ohio State University Comprehensive Cancer Center, Columbus, OH; Gabriel Capella and Marta Pineda, Institut d'Investigació Biomédica de Bellvitge, Barcelona, Spain; Steven Gallinger, Mount Sinai Hospital, Toronto, Ontario, Canada; Jane C. Figueiredo and Robert Haile, Cedars-Sinai Medical Center, Los Angeles, CA; Loic Le Marchand, University of Hawaii Cancer Center, Honolulu, HI; Annika Lindblom, Karolinska Institutet; Karolinska University Hospital, Stockholm, Sweden; Noralane M. Lindor, Mayo Clinic Arizona, Scottsdale, AZ; Polly A. Newcomb, Fred Hutchinson Cancer Research Center; University of Washington, Seattle, WA; and Stephen Thibodeau, Mayo Clinic, Rochester, MN.

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http://ascopubs.org/doi/10.1200/JCO.2018.78.4777
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http://dx.doi.org/10.1200/JCO.2018.78.4777DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349460PMC
October 2018

Loss of MSH2 and MSH6 due to heterozygous germline defects in MSH3 and MSH6.

Fam Cancer 2017 Oct;16(4):491-500

Medizinische Klinik und Poliklinik IV, Campus Innenstadt, Klinikum der Universität München, Ziemssenstr. 1, 80336, Munich, Germany.

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http://dx.doi.org/10.1007/s10689-017-9975-zDOI Listing
October 2017

Prevalence of germline mutations in the spindle assembly checkpoint gene BUB1B in individuals with early-onset colorectal cancer.

Genes Chromosomes Cancer 2016 11 7;55(11):855-63. Epub 2016 Jul 7.

Department of Human Genetics, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1002/gcc.22385DOI Listing
November 2016

An unusual case of Cowden syndrome associated with ganglioneuromatous polyposis.

Hered Cancer Clin Pract 2016 10;14:11. Epub 2016 May 10.

Department of Surgical Research, Technische Universität Dresden, Fetscherstr. 74, Dresden, 01307 Germany.

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http://dx.doi.org/10.1186/s13053-016-0051-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862217PMC
May 2016

Analysis of gastrin-releasing peptide gene and gastrin-releasing peptide receptor gene in patients with agoraphobia.

Psychiatr Genet 2014 Oct;24(5):232-3

Departments of aPsychotherapy and Psychosomatic Medicine bSurgical Research cConservative Dentistry, University Hospital Carl Gustav Carus dInstitute of Clinical Psychology and Psychotherapy eInstitute of Psychology II, Technische Universität Dresden fDepartment of Psychiatry, Städtisches Krankenhaus Dresden-Friedrichstadt, Dresden gBliestal Clinics, Department of Psychosomatic Medicine and Psychotherapy, Blieskastel hInstitute for Medical Biometry and Statistics, University Hospital Schleswig-Holstein iCenter for Clinical Trials, University of Lübeck, Lübeck, Germany.

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http://pdfs.journals.lww.com/psychgenetics/2014/10000/Analys
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/YPG.0000000000000038DOI Listing
October 2014

Complete homozygous deletion of CTSC in an Iranian family with Papillon-Lefèvre syndrome.

Int J Dermatol 2014 Jul 4;53(7):885-7. Epub 2013 Apr 4.

Department of Surgical Research, Technische Universität Dresden, Dresden, Germany.

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http://dx.doi.org/10.1111/j.1365-4632.2012.05769.xDOI Listing
July 2014

Germline truncating-mutations in BRCA1 and MSH6 in a patient with early onset endometrial cancer.

BMC Cancer 2012 Nov 20;12:531. Epub 2012 Nov 20.

Department of Gynecology and Obstetrics, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.

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http://dx.doi.org/10.1186/1471-2407-12-531DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3537684PMC
November 2012

Aberrant protein expression and frequent allelic loss of MSH3 in colorectal cancer with low-level microsatellite instability.

Int J Colorectal Dis 2012 Jul 10;27(7):911-9. Epub 2012 Jan 10.

Department of Surgical Research, Carl Gustav Carus Klinikum, Technical University Dresden, Fetscherstr. 74, 01307 Dresden, Germany.

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http://link.springer.com/10.1007/s00384-011-1408-0
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http://dx.doi.org/10.1007/s00384-011-1408-0DOI Listing
July 2012

An American founder mutation in MLH1.

Int J Cancer 2012 May 30;130(9):2088-95. Epub 2011 Aug 30.

Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1002/ijc.26233DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266960PMC
May 2012

RET-protooncogene variants in patients with sporadic neoplasms of the digestive tract and the central nervous system.

Int J Colorectal Dis 2011 Jul 11;26(7):835-40. Epub 2011 Feb 11.

Department of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstr, Dresden, Germany.

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http://dx.doi.org/10.1007/s00384-011-1150-7DOI Listing
July 2011

Analysis of EPCAM protein expression in diagnostics of Lynch syndrome.

J Clin Oncol 2011 Jan 29;29(2):223-7. Epub 2010 Nov 29.

Department of Applied Tumor Biology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1200/JCO.2010.32.0820DOI Listing
January 2011

TCF-3, 4 protein expression correlates with beta-catenin expression in MSS and MSI-H colorectal cancer from HNPCC patients but not in sporadic colorectal cancers.

Int J Colorectal Dis 2010 Aug 8;25(8):931-9. Epub 2010 Jun 8.

Department of Surgical Research, Technische Universität Dresden, Dresden, Germany.

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http://link.springer.com/10.1007/s00384-010-0959-9
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http://dx.doi.org/10.1007/s00384-010-0959-9DOI Listing
August 2010

Analysis of RET, ZEB2, EDN3 and GDNF genomic rearrangements in central congenital hyperventilation syndrome patients by multiplex ligation-dependent probe amplification.

Ann Hum Genet 2010 Jul 25;74(4):369-74. Epub 2010 Apr 25.

Department of Surgery (Section Pediatric Surgery), University of Ulm, Ulm, Germany.

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http://dx.doi.org/10.1111/j.1469-1809.2010.00577.xDOI Listing
July 2010

Rare occurrence of PHOX2b mutations in sporadic neuroblastomas.

J Pediatr Hematol Oncol 2008 Oct;30(10):728-32

Department of Pediatric Surgery, Technische Universität Dresden, Dresden, Germany.

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http://dx.doi.org/10.1097/MPH.0b013e3181772141DOI Listing
October 2008

t(11;19)(q21;p12~p13.11) and MECT1-MAML2 fusion transcript expression as a prognostic marker in infantile lung mucoepidermoid carcinoma.

J Pediatr Surg 2007 Jul;42(7):E23-9

Department of Pediatric Surgery, University of Dresden, D-01307 Dresden, Germany.

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http://dx.doi.org/10.1016/j.jpedsurg.2007.04.031DOI Listing
July 2007

Analysis of the base excision repair genes MTH1, OGG1 and MUTYH in patients with squamous oral carcinomas.

Oral Oncol 2007 Sep 4;43(8):791-5. Epub 2007 Jan 4.

Department of Surgical Research, Technische Universität Dresden, D-01307 Dresden, Germany.

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http://linkinghub.elsevier.com/retrieve/pii/S136883750600282
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http://dx.doi.org/10.1016/j.oraloncology.2006.10.004DOI Listing
September 2007

N-Acetyltransferase (NAT) 2 acetylator status and age of tumour onset in patients with sporadic and familial, microsatellite stable (MSS) colorectal cancer.

Int J Colorectal Dis 2007 Feb 2;22(2):137-43. Epub 2006 Aug 2.

Department of Visceral, Thoracic and Vascular Surgery, University of Technology Dresden, Fetscherstr. 74, 01307 Dresden, Germany.

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http://dx.doi.org/10.1007/s00384-006-0171-0DOI Listing
February 2007

Genomic rearrangements in MSH2, MLH1 or MSH6 are rare in HNPCC patients carrying point mutations.

Cancer Lett 2007 Apr 11;248(1):89-95. Epub 2006 Jul 11.

Department of Visceral, Thoracic and Vascular Surgery, Technische Universität Dresden, Fetscherstr. 74, 01307 Dresden, Germany.

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http://dx.doi.org/10.1016/j.canlet.2006.06.002DOI Listing
April 2007

The role of endothelial nitric oxide synthase (eNOS) genetic variants in European patients with intracranial aneurysms.

J Cereb Blood Flow Metab 2006 Oct 8;26(10):1250-5. Epub 2006 Feb 8.

Department of Neurosurgery, Carl Gustav Carus Hospital of University of Technology, Dresden, Germany.

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http://dx.doi.org/10.1038/sj.jcbfm.9600284DOI Listing
October 2006

Highly specific overexpression of the transcription factor SOX11 in human malignant gliomas.

Oncol Rep 2005 Jan;13(1):139-44

Institute of Immunology, Technical University of Dresden, 01307 Dresden, Germany.

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January 2005

Ten novel MSH2 and MLH1 germline mutations in families with HNPCC.

Hum Mutat 2004 Oct;24(4):351-2

Department of Surgical Research, Universitätsklinikum Carl Gustav Carus, Dresden University of Technology, Dresden, Germany.

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http://dx.doi.org/10.1002/humu.9278DOI Listing
October 2004

Molecular mechanisms associated with chromosomal and microsatellite instability in sporadic glioblastoma multiforme.

Oncology 2004 ;66(5):395-403

Department of Neurosurgery, Institute of Pathology of the University of Dresden, Dresden, Germany.

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http://dx.doi.org/10.1159/000079488DOI Listing
September 2004

One-step analysis of ten functional haplotype combinations of the basic RET promoter with a LightCycler assay.

Clin Chem 2004 Sep 20;50(9):1693-5. Epub 2004 Jul 20.

Department of Surgical Research, Universitätsklinikum Carl Gustav Carus, Dresden University of Technology, Germany.

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http://dx.doi.org/10.1373/clinchem.2004.034165DOI Listing
September 2004

Extended single nucleotide polymorphism and haplotype analysis of the elastin gene in Caucasians with intracranial aneurysms provides evidence for racially/ethnically based differences.

Cerebrovasc Dis 2004 22;18(2):104-10. Epub 2004 Jun 22.

Department of Neurosurgery, University Hospital Carl Gustav Carus, University of Technology, Dresden, Germany.

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http://dx.doi.org/10.1159/000079257DOI Listing
October 2004

Matrix metalloproteinase-9 coding sequence single-nucleotide polymorphisms in caucasians with intracranial aneurysms.

Neurosurgery 2004 Jul;55(1):207-12; discussion 212-3

Department of Neurosurgery, University Hospital Carl Gustav Carus, University of Technology, Dresden, Germany.

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http://dx.doi.org/10.1227/01.neu.0000126882.17878.6dDOI Listing
July 2004

Loss of expression of ZAC/LOT1 in squamous cell carcinomas of head and neck.

Head Neck 2004 Apr;26(4):338-44

Department of Oral and Maxillofacial Surgery, University Hospital Carl Gustav Carus, Technical University Dresden, Fetscherst. 74, 01307 Dresden, Germany.

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http://dx.doi.org/10.1002/hed.10386DOI Listing
April 2004

Loss of MSH3 protein expression is frequent in MLH1-deficient colorectal cancer and is associated with disease progression.

Cancer Res 2004 Feb;64(3):864-70

Department of Surgical Research, Institute of Pathology, Institute of Clinical Genetics, Carl Gustav Carus Hospital, Dresden University of Technology, Dresden, Germany.

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http://dx.doi.org/10.1158/0008-5472.can-03-2807DOI Listing
February 2004

Genetic analysis of a multifocal glioblastoma multiforme: a suitable tool to gain new aspects in glioma development.

Neurosurgery 2003 Dec;53(6):1377-84; discussion 1384

Department of Neurosurgery, University Hospital Carl Gustav Carus, University of Technology, Dresden, Germany.

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http://dx.doi.org/10.1227/01.neu.0000093426.29236.86DOI Listing
December 2003

Tissue inhibitor of metalloproteinases-1, -2, and -3 polymorphisms in a white population with intracranial aneurysms.

Stroke 2003 Dec 6;34(12):2817-21. Epub 2003 Nov 6.

Department of Neurosurgery, University Hospital Carl Gustav Carus, University of Technology, Dresden, Germany.

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http://dx.doi.org/10.1161/01.STR.0000099966.51485.5FDOI Listing
December 2003

Functional haplotypes of the RET proto-oncogene promoter are associated with Hirschsprung disease (HSCR).

Hum Mol Genet 2003 Dec 4;12(24):3207-14. Epub 2003 Nov 4.

Department of Pediatric Surgery, University of Technology Dresden, Germany.

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http://dx.doi.org/10.1093/hmg/ddg354DOI Listing
December 2003

Polymorphisms of the NADPH oxidase P22PHOX gene in a Caucasian population with intracranial aneurysms.

Cerebrovasc Dis 2003 ;16(4):363-8

Department of Neurosurgery, University Hospital Carl Gustav Carus, University of Technology, Dresden, Germany.

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http://dx.doi.org/10.1159/000072558DOI Listing
January 2004

LightCycler assay in the analysis of haplotypes of the type 2 diabetes susceptibility gene CAPN10.

Clin Chem 2003 Aug;49(8):1405-8

Department of Surgical Research, Universitätsklinikum Carl Gustav Carus-Dresden, University of Technology, Fetscherstrasse 74, D-01307 Dresden, Germany.

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http://dx.doi.org/10.1373/49.8.1405DOI Listing
August 2003

Novel intronic polymorphisms in the RET proto-oncogene and their association with Hirschsprung disease.

Hum Mutat 2003 Aug;22(2):177

Department of Pediatric Surgery, University of Technology Dresden, Germany.

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http://dx.doi.org/10.1002/humu.9161DOI Listing
August 2003

Preventive surgery for colon cancer in familial adenomatous polyposis and hereditary nonpolyposis colorectal cancer syndrome.

Langenbecks Arch Surg 2003 Mar 27;388(1):9-16. Epub 2003 Mar 27.

Klinik für Allgemeine und Unfallchirurgie, Moorenstrasse 5, 40225 Düsseldorf, Germany.

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http://dx.doi.org/10.1007/s00423-003-0364-8DOI Listing
March 2003

Identification of microsatellite instability and mismatch repair gene mutations in breast cancer cell lines.

Genes Chromosomes Cancer 2003 May;37(1):29-35

Abteilung Tumorgenetik, Max-Delbrück-Centrum für Molekulare Medizin, Berlin, Germany.

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http://doi.wiley.com/10.1002/gcc.10196
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http://dx.doi.org/10.1002/gcc.10196DOI Listing
May 2003

Identification of six novel MSH2 and MLH1 germline mutations in HNPCC.

Hum Mutat 2003 Apr;21(4):445-6

Department of Surgical Research, Universitätsklinikum Carl Gustav Carus, University of Technology, Dresden, Germany.

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http://dx.doi.org/10.1002/humu.9121DOI Listing
April 2003

Methylenetetrahydrofolate reductase polymorphisms and risk of sporadic and hereditary colorectal cancer with or without microsatellite instability.

Cancer Lett 2003 Mar;191(2):179-85

Department of Surgical Research, Carl Gustav Carus Hospital, Dresden University of Technology, Fetscherstrasse 74, D-01307 Dresden, Germany.

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http://dx.doi.org/10.1016/s0304-3835(02)00633-xDOI Listing
March 2003

Various penetrance of familial medullary thyroid carcinoma in patients with RET protooncogene codon 790/791 germline mutations.

Ann Surg 2002 Nov;236(5):570-5

Departments of Pediatric Surgery, General Surgery, Nuclear Medicine, and Surgical Research, University of Technology Dresden, Dresden, Germany.

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http://dx.doi.org/10.1097/00000658-200211000-00006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1422614PMC
November 2002

Association between c135G/A genotype and RET proto-oncogene germline mutations and phenotype of Hirschsprung's disease.

Lancet 2002 Apr;359(9313):1200-5

Department of Paediatric Surgery, University of Technology Dresden, Fetscherstrasse 74, D-01307 Dresden, Germany.

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http://dx.doi.org/10.1016/S0140-6736(02)08218-1DOI Listing
April 2002

Seven novel MLH1 and MSH2 germline mutations in hereditary nonpolyposis colorectal cancer.

Hum Mutat 2002 Jan;19(1):82

Department of Surgical Research, Universitätsklinikum Carl Gustav Carus, University of Technology, Dresden, Germany.

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http://dx.doi.org/10.1002/humu.9004DOI Listing
January 2002