Publications by authors named "Hans D Ochs"

100Publications

Targeting FcRn for immunomodulation: Benefits, risks, and practical considerations.

J Allergy Clin Immunol 2020 Sep;146(3):479-491.e5

Immunodeficiency Centre for Wales, University Hospital of Wales, Cardiff, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2020.07.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471860PMC
September 2020

Quantity does not equal quality: Scientific principles cannot be sacrificed.

Int Immunopharmacol 2020 Sep 22;86:106711. Epub 2020 Jun 22.

Research Center for Immunodeficiencies, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran; Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran; Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran. Electronic address:

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http://dx.doi.org/10.1016/j.intimp.2020.106711DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307981PMC
September 2020

Immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome: A systematic review.

Autoimmun Rev 2020 Jun 29;19(6):102526. Epub 2020 Mar 29.

Department of Pediatrics, Yonsei University College of Medicine, Seoul, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.autrev.2020.102526DOI Listing
June 2020

A 71-year-old man with recurrent pulmonary mycobacterial avium complex infections and lymphopenia.

Allergy Asthma Proc 2020 01;41(1):66-69

From the Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington.

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http://dx.doi.org/10.2500/aap.2020.41.190003DOI Listing
January 2020

Lazy Leukocyte Syndrome-an Enigma Finally Solved?

J Clin Immunol 2020 01 25;40(1):9-12. Epub 2019 Nov 25.

University of Washington and Seattle Children's Research Institute, Seattle, WA, USA.

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http://dx.doi.org/10.1007/s10875-019-00718-0DOI Listing
January 2020

CD40 ligand deficiency: treatment strategies and novel therapeutic perspectives.

Expert Rev Clin Immunol 2019 05 18;15(5):529-540. Epub 2019 Feb 18.

a Department of Immunology, Institute of Biomedical Sciences , University of São Paulo , São Paulo , Brazil.

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https://www.tandfonline.com/doi/full/10.1080/1744666X.2019.1
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http://dx.doi.org/10.1080/1744666X.2019.1573674DOI Listing
May 2019

Tuberculosis and impaired IL-23-dependent IFN-γ immunity in humans homozygous for a common missense variant.

Sci Immunol 2018 12;3(30)

St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, USA.

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http://immunology.sciencemag.org/lookup/doi/10.1126/sciimmun
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http://dx.doi.org/10.1126/sciimmunol.aau8714DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341984PMC
December 2018

Corrigendum: A Novel Homozygous Mutation Leading to T-B+NK- SCID in Two Brazilian Patients.

Front Pediatr 2018 23;6:358. Epub 2018 Nov 23.

Laboratory of Human Immunology, Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.

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http://dx.doi.org/10.3389/fped.2018.00358DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265411PMC
November 2018

Hyper IgE syndromes: clinical and molecular characteristics.

Immunol Cell Biol 2019 04 19;97(4):368-379. Epub 2018 Nov 19.

Seattle Children's Research Institute, Seattle, Washington, USA.

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http://dx.doi.org/10.1111/imcb.12209DOI Listing
April 2019

Comparison of Common Monogenic Defects in a Large Predominantly Antibody Deficiency Cohort.

Authors:
Reza Yazdani Hassan Abolhassani Fatemeh Kiaee Sima Habibi Gholamreza Azizi Marzieh Tavakol Zahra Chavoshzadeh Seyed Alireza Mahdaviani Tooba Momen Mohammad Gharagozlou Masoud Movahedi Amir Ali Hamidieh Nasrin Behniafard Mohammamd Nabavi Mohammad Hassan Bemanian Saba Arshi Rasol Molatefi Roya Sherkat Afshin Shirkani Reza Amin Soheila Aleyasin Reza Faridhosseini Farahzad Jabbari-Azad Iraj Mohammadzadeh Javad Ghaffari Alireza Shafiei Arash Kalantari Mahboubeh Mansouri Mehrnaz Mesdaghi Delara Babaie Hamid Ahanchian Maryam Khoshkhui Habib Soheili Mohammad Hossein Eslamian Taher Cheraghi Abbas Dabbaghzadeh Mahmoud Tavassoli Rasoul Nasiri Kalmarzi Seyed Hamidreza Mortazavi Sara Kashef Hossein Esmaeilzadeh Javad Tafaroji Abbas Khalili Fariborz Zandieh Mahnaz Sadeghi-Shabestari Sepideh Darougar Fatemeh Behmanesh Hedayat Akbari Mohammadreza Zandkarimi Farhad Abolnezhadian Abbas Fayezi Mojgan Moghtaderi Akefeh Ahmadiafshar Behzad Shakerian Vahid Sajedi Behrang Taghvaei Mojgan Safari Marzieh Heidarzadeh Babak Ghalebaghi Seyed Mohammad Fathi Behzad Darabi Saeed Bazregari Nasrin Bazargan Morteza Fallahpour Alireza Khayatzadeh Naser Javahertrash Bahram Bashardoust Mohammadali Zamani Azam Mohsenzadeh Sarehsadat Ebrahimi Samin Sharafian Ahmad Vosughimotlagh Mitra Tafakoridelbari Maziar Rahim Parisa Ashournia Anahita Razaghian Arezou Rezaei Ashraf Samavat Setareh Mamishi Hossein Ali Khazaei Javad Mohammadi Babak Negahdari Nima Parvaneh Nima Rezaei Vassilios Lougaris Silvia Giliani Alessandro Plebani Hans D Ochs Lennart Hammarström Asghar Aghamohammadi

J Allergy Clin Immunol Pract 2019 03 19;7(3):864-878.e9. Epub 2018 Sep 19.

Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran; Iranian Primary Immunodeficiencies Network (IPIN), Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

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http://dx.doi.org/10.1016/j.jaip.2018.09.004DOI Listing
March 2019

A Novel Homozygous Mutation Leading to T-B+NK- SCID in Two Brazilian Patients.

Front Pediatr 2018 20;6:230. Epub 2018 Aug 20.

Laboratory of Human Immunology, Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.

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http://dx.doi.org/10.3389/fped.2018.00230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109756PMC
August 2018

Intravenous immunoglobulin 10% in children with primary immunodeficiency diseases.

Immunotherapy 2018 10 8;10(14):1193-1202. Epub 2018 Aug 8.

Division of Pediatric Allergy and Immunology, Department of Pediatrics, UCLA School of Medicine, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.2217/imt-2018-0074DOI Listing
October 2018

Pharmacokinetics of a novel human intravenous immunoglobulin 10% in patients with primary immunodeficiency diseases: Analysis of a phase III, multicentre, prospective, open-label study.

Eur J Pharm Sci 2018 Jun 6;118:80-86. Epub 2018 Mar 6.

Division of Pediatric Allergy/Immunology, John H. Stroger, Jr. Hospital of Cook County, 1969 W. Ogden Ave., Chicago, IL 60612, USA; Rush University Medical Center, 1653 W. Congress Parkway, Chicago, IL 60612, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ejps.2018.03.007DOI Listing
June 2018

Ralph Josiah Patrick Wedgwood (1924-2017).

J Clin Immunol 2018 02 27;38(2):153-154. Epub 2017 Dec 27.

Department of Pediatrics, British Columbia Children's Hospital, International Pediatric Association, Vancouver, BC, V6H 3V4, Canada.

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http://dx.doi.org/10.1007/s10875-017-0471-xDOI Listing
February 2018

R-loops cause genomic instability in T helper lymphocytes from patients with Wiskott-Aldrich syndrome.

J Allergy Clin Immunol 2018 07 15;142(1):219-234. Epub 2017 Dec 15.

Division of Pediatric Hematology-Oncology, Carver College of Medicine and the University of Iowa Stead Family Children's Hospital, Iowa City, Md. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.11.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003829PMC
July 2018

Paternal gonadal mosaicism as cause of a puzzling inheritance pattern of activated PI3-kinase delta syndrome.

Ann Allergy Asthma Immunol 2017 12 6;119(6):564-566. Epub 2017 Nov 6.

Department of Pediatrics, University of Washington, Seattle, Washington; Seattle Children's Hospital, Seattle, Washington.

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http://dx.doi.org/10.1016/j.anai.2017.09.054DOI Listing
December 2017

From clinical observations and molecular dissection to novel therapeutic strategies for primary immunodeficiency disorders.

Am J Med Genet A 2018 Apr 21;176(4):784-803. Epub 2017 Sep 21.

Department of Pediatrics and Seattle Children's Research Institute, University of Washington, Seattle, Washington.

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http://dx.doi.org/10.1002/ajmg.a.38480DOI Listing
April 2018

Flow cytometry-based diagnosis of primary immunodeficiency diseases.

Allergol Int 2018 Jan 3;67(1):43-54. Epub 2017 Jul 3.

Department of Pediatrics and Developmental Biology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.

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http://dx.doi.org/10.1016/j.alit.2017.06.003DOI Listing
January 2018

Cancer in primary immunodeficiency diseases: Cancer incidence in the United States Immune Deficiency Network Registry.

J Allergy Clin Immunol 2018 03 9;141(3):1028-1035. Epub 2017 Jun 9.

Department of Immunology, Roswell Park Cancer Institute, Buffalo, NY; Department of Medicine, Roswell Park Cancer Institute, Buffalo, NY; Department of Medicine, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, Buffalo, NY. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.05.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723251PMC
March 2018

Absence of functional fetal regulatory T cells in humans causes in utero organ-specific autoimmunity.

J Allergy Clin Immunol 2017 08 16;140(2):616-619.e7. Epub 2017 Mar 16.

Department of Pediatrics, University of Washington School of Medicine, Seattle, Wash; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, Wash. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.02.017DOI Listing
August 2017

Autoimmunity in common variable immunodeficiency: epidemiology, pathophysiology and management.

Expert Rev Clin Immunol 2017 Feb 16;13(2):101-115. Epub 2016 Sep 16.

b Research Center for Immunodeficiencies, Pediatrics Center of Excellence , Children's Medical Center, Tehran University of Medical Sciences , Tehran , Iran.

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http://dx.doi.org/10.1080/1744666X.2016.1224664DOI Listing
February 2017

Rubella persistence in epidermal keratinocytes and granuloma M2 macrophages in patients with primary immunodeficiencies.

J Allergy Clin Immunol 2016 11 6;138(5):1436-1439.e11. Epub 2016 Sep 6.

Division of Allergy Immunology, the Children's Hospital of Philadelphia, Philadelphia, Pa. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2016.06.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392721PMC
November 2016

X-linked Hyper IgM Syndrome Presenting as Pulmonary Alveolar Proteinosis.

J Clin Immunol 2016 08 20;36(6):564-70. Epub 2016 Jun 20.

Division of Asthma, Department of Pediatrics, Allergy and Clinical Immunology, Medical College of Wisconsin, Milwaukee, WI, USA.

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http://dx.doi.org/10.1007/s10875-016-0307-0DOI Listing
August 2016

Targeted gene editing restores regulated CD40L function in X-linked hyper-IgM syndrome.

Blood 2016 05 22;127(21):2513-22. Epub 2016 Feb 22.

Center for Immunity and Immunotherapies and Program for Cell and Gene Therapy, Seattle Children's Research Institute, Seattle, WA; and Department of Pediatrics and.

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http://dx.doi.org/10.1182/blood-2015-11-683235DOI Listing
May 2016

Quantitative analysis of tissue inflammation and responses to treatment in immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome, and review of literature.

J Microbiol Immunol Infect 2016 Oct 1;49(5):775-782. Epub 2015 Dec 1.

Department of Pediatrics, National Cheng Kung University Hospital, Tainan, Taiwan; Institute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.jmii.2015.10.015DOI Listing
October 2016

Soluble molecules in intravenous immunoglobulin: benefits and limitations.

Expert Rev Clin Immunol 2016 9;12(2):99-101. Epub 2015 Dec 9.

a Department of Immunology, School of Medicine , Tehran University of Medical Sciences , Tehran , Iran.

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http://dx.doi.org/10.1586/1744666X.2016.1111138DOI Listing
November 2016

Successful hematopoietic cell transplantation in a patient with X-linked agammaglobulinemia and acute myeloid leukemia.

Pediatr Blood Cancer 2015 Sep 20;62(9):1674-6. Epub 2015 Apr 20.

Pediatric Blood and Marrow Transplant, Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, Maryland.

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http://dx.doi.org/10.1002/pbc.25554DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876715PMC
September 2015

An emerging era of clinical benefit from gene therapy.

JAMA 2015 Apr;313(15):1522-3

Department of Pediatrics, University of Washington and Seattle Children's Research Institute, Seattle.

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http://dx.doi.org/10.1001/jama.2015.2055DOI Listing
April 2015

Autoimmunity and inflammation in X-linked agammaglobulinemia.

J Clin Immunol 2014 Aug 10;34(6):627-32. Epub 2014 Jun 10.

Division of Allergy and Immunology, Department of Pediatrics, Miami Children's Hospital, 3100 SW 62 Avenue, Miami, FL, 33155, USA,

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http://usidnet.org/wp-content/uploads/2014/07/XLA-paper.pdf
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http://link.springer.com/10.1007/s10875-014-0056-x
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http://dx.doi.org/10.1007/s10875-014-0056-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157090PMC
August 2014

Primary immunodeficiency disorders: general classification, new molecular insights, and practical approach to diagnosis and treatment.

Ann Allergy Asthma Immunol 2014 Jun;112(6):489-95

Seattle Children's Research Institute, University of Washington, Seattle, Washington.

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http://dx.doi.org/10.1016/j.anai.2014.04.007DOI Listing
June 2014

Analysis of somatic hypermutations in the IgM switch region in human B cells.

J Allergy Clin Immunol 2014 Aug 15;134(2):411-9. Epub 2014 May 15.

Department of Pediatrics, National Defense Medical College, Saitama, Japan.

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http://dx.doi.org/10.1016/j.jaci.2014.02.043DOI Listing
August 2014

Primary immunodeficiency diseases: an update on the classification from the international union of immunological societies expert committee for primary immunodeficiency.

Front Immunol 2014 22;5:162. Epub 2014 Apr 22.

Murdoch Childrens Research Institute , Melbourne, VIC , Australia ; Department of Paediatrics, University of Melbourne , Melbourne, VIC , Australia ; Department of Allergy and Immunology, Royal Children's Hospital , Melbourne, VIC , Australia.

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http://dx.doi.org/10.3389/fimmu.2014.00162DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4001072PMC
May 2014

First report of the Hyper-IgM syndrome Registry of the Latin American Society for Immunodeficiencies: novel mutations, unique infections, and outcomes.

J Clin Immunol 2014 Feb 9;34(2):146-56. Epub 2014 Jan 9.

Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, 1730 Lineu Prestes Avenue, São Paulo, SP, ZIP 05508-000, Brazil.

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http://link.springer.com/10.1007/s10875-013-9980-4
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http://dx.doi.org/10.1007/s10875-013-9980-4DOI Listing
February 2014

Ocular involvement in primary immunodeficiency diseases.

J Clin Immunol 2014 Jan 30;34(1):23-38. Epub 2013 Nov 30.

Research Center for Immunodeficiencies, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.1007/s10875-013-9974-2DOI Listing
January 2014

Coding-region alterations in BTK do not universally cause X-linked agammaglobulinemia.

J Allergy Clin Immunol 2013 Nov 31;132(5):1246-8. Epub 2013 Aug 31.

Division of Allergy and Immunology, Department of Pediatrics, National Jewish Health, Denver, Colo.

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http://dx.doi.org/10.1016/j.jaci.2013.07.019DOI Listing
November 2013

Diagnosis and evaluation of primary panhypogammaglobulinemia: a molecular and genetic challenge.

J Allergy Clin Immunol 2013 Jun;131(6):1717-8

Division of Allergy and Immunology, Department of Pediatrics, National Jewish Health, Denver, CO 80206, USA.

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http://dx.doi.org/10.1016/j.jaci.2013.03.045DOI Listing
June 2013

Controversies in IgG replacement therapy in patients with antibody deficiency diseases.

J Allergy Clin Immunol 2013 Apr;131(4):1001-5

Division of Cell Biology, Department of Pediatrics, National Jewish Health, Denver, CO, USA.

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http://dx.doi.org/10.1016/j.jaci.2013.02.028DOI Listing
April 2013

History of primary immunodeficiency diseases.

Curr Opin Allergy Clin Immunol 2012 Dec;12(6):577-87

Department of Pediatrics, University of Washington School of Medicine and Seattle Children's Research Institute, Seattle, Washington 98101, USA.

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http://dx.doi.org/10.1097/ACI.0b013e32835923a6DOI Listing
December 2012

Home-based subcutaneous immunoglobulin versus hospital-based intravenous immunoglobulin in treatment of primary antibody deficiencies: systematic review and meta analysis.

J Clin Immunol 2012 Dec 23;32(6):1180-92. Epub 2012 Jun 23.

Children's Medical Center, Tehran University of Medical Sciences, Dr Qarib St, Keshavarz Blvd, Tehran, 14194, Iran.

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http://dx.doi.org/10.1007/s10875-012-9720-1DOI Listing
December 2012

Primary immunodeficiency diseases associated with neurologic manifestations.

J Clin Immunol 2012 Feb 26;32(1):1-24. Epub 2011 Oct 26.

Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, 14194, Iran.

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http://dx.doi.org/10.1007/s10875-011-9593-8DOI Listing
February 2012

Genetic analysis of contiguous X-chromosome deletion syndrome encompassing the BTK and TIMM8A genes.

J Hum Genet 2011 Aug 14;56(8):577-82. Epub 2011 Jul 14.

Division of Clinical Research, Saitama Children's Medical Center, Saitama, Japan.

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http://www.nature.com/articles/jhg201161
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http://dx.doi.org/10.1038/jhg.2011.61DOI Listing
August 2011

Indications and safety of intravenous and subcutaneous immunoglobulin therapy.

Expert Rev Clin Immunol 2011 May;7(3):301-16

Molecular Immunology Research Center and Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.1586/eci.10.104DOI Listing
May 2011