Hannah Carter

Hannah Carter

UNVERIFIED PROFILE

Are you Hannah Carter?   Register this Author

Register author
Hannah Carter

Hannah Carter

Publications by authors named "Hannah Carter"

Are you Hannah Carter?   Register this Author

49Publications

-Reads

The Emerging Potential for Network Analysis to Inform Precision Cancer Medicine.

J Mol Biol 2018 Sep 15;430(18 Pt A):2875-2899. Epub 2018 Jun 15.

Department of Medicine, Division of Medical Genetics, University of California San Diego, La Jolla, CA 92093, USA; Bioinformatics and Systems Biology Program, University of California San Diego, La Jolla, CA 92093, USA; Moores Cancer Center and Institute for Genomic Medicine, University of California San Diego, La Jolla, CA 92093, USA; CIFAR, MaRS Centre, West Tower, 661 University Ave., Suite 505, Toronto, ON M5G 1M1, Canada. Electronic address:

View Article
September 2018

Exome-wide analysis of bi-allelic alterations identifies a Lynch phenotype in The Cancer Genome Atlas.

Genome Med 2018 Sep 14;10(1):69. Epub 2018 Sep 14.

Human Biology Program, J. Craig Venter Institute, La Jolla, CA, USA.

View Article
September 2018

Medication Allergy and Adverse Drug Reaction Documentation Discrepancies in an Urban, Academic Emergency Department.

J Med Toxicol 2018 Jul 2. Epub 2018 Jul 2.

Department of Emergency Medicine, MedStar Washington Hospital Center, 110 Irving Street NW, Suite NA 1009, Washington, DC, 20010, USA.

View Article
July 2018

MHC-I genotype drives early immune selection of oncogenic mutations.

Mol Cell Oncol 2018 25;5(2):e1409863. Epub 2018 Jan 25.

Cancer Biology Program, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA, USA.

View Article
January 2018

MHC-I Genotype Restricts the Oncogenic Mutational Landscape.

Cell 2017 Nov 26;171(6):1272-1283.e15. Epub 2017 Oct 26.

Department of Medicine, Division of Medical Genetics, University of California San Diego, La Jolla, CA 92093, USA; Bioinformatics and Systems Biology Program, University of California San Diego, La Jolla, CA 92093, USA; Moores Cancer Center, University of California San Diego, La Jolla, CA 92093, USA; Cancer Cell Map Initiative (CCMI), University of California San Diego, La Jolla, CA 92093, USA.

View Article
November 2017

Modeling of RAS complexes supports roles in cancer for less studied partners.

BMC Biophys 2017 11;10(Suppl 1). Epub 2017 Aug 11.

Division of Medical Genetics, Department of Medicine, Universsity of California, San Diego, 9500 Gilman Dr., La Jolla, CA 92093 USA.

View Article
August 2017

The Productivity Costs of Premature Mortality Due to Cancer in Australia: Evidence from a Microsimulation Model.

PLoS One 2016 12;11(12):e0167521. Epub 2016 Dec 12.

Faculty of Pharmacy, University of Sydney, Sydney, Australia.

View Article
June 2017

Interaction Landscape of Inherited Polymorphisms with Somatic Events in Cancer.

Cancer Discov 2017 04 10;7(4):410-423. Epub 2017 Feb 10.

Department of Medicine, Division of Medical Genetics, University of California, San Diego, La Jolla, California.

View Article
April 2017

Common genetic variation in the germline influences where and how tumors develop.

Mol Cell Oncol 2017 10;4(3):e1302905. Epub 2017 Mar 10.

Department of Medicine, Division of Medical Genetics, University of California San Diego, La Jolla, CA, USA.

View Article
March 2017

The long-term productivity impacts of all cause premature mortality in Australia.

Aust N Z J Public Health 2016 Nov 20. Epub 2016 Nov 20.

Faculty of Pharmacy, University of Sydney, New South Wales.

View Article
November 2016

Structure-Based Analysis Reveals Cancer Missense Mutations Target Protein Interaction Interfaces.

PLoS One 2016 4;11(4):e0152929. Epub 2016 Apr 4.

Division of Medical Genetics, Department of Medicine, University of California, San Diego, 9500 Gilman Dr., La Jolla, CA, 92093, United States of America.

View Article
August 2016

Challenges in identifying cancer genes by analysis of exome sequencing data.

Nat Commun 2016 07 15;7:12096. Epub 2016 Jul 15.

Cancer Cell Map Initiative (CCMI), 9500 Gilman Drive, La Jolla, California 92093, USA.

View Article
July 2016

Immune DNA signature of T-cell infiltration in breast tumor exomes.

Sci Rep 2016 07 25;6:30064. Epub 2016 Jul 25.

Division of Biomedical Informatics, Department of Medicine, University of California San Diego, United States.

View Article
July 2016

VarI-SIG 2015: methods for personalized medicine - the role of variant interpretation in research and diagnostics.

BMC Genomics 2016 06 23;17 Suppl 2:425. Epub 2016 Jun 23.

Division of Medical Genetics, Department of Medicine, University of California, San Diego, 9500 Gilman Dr., 92093, La Jolla, CA, USA.

View Article
June 2016

Identifying mutation specific cancer pathways using a structurally resolved protein interaction network.

Pac Symp Biocomput 2015 :84-95

School of Medicine, University of California San Diego, 9500 Gilman Dr. San Diego, CA 92093, USA.

View Article
April 2016

Hybrid Periportal Hepatocytes Regenerate the Injured Liver without Giving Rise to Cancer.

Cell 2015 Aug;162(4):766-79

Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, School of Medicine, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA; Department of Pathology, School of Medicine, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA. Electronic address:

View Article
August 2015

Multi-tiered genomic analysis of head and neck cancer ties TP53 mutation to 3p loss.

Nat Genet 2014 Sep 3;46(9):939-43. Epub 2014 Aug 3.

1] Bioinformatics and Systems Biology Program, University of California, San Diego, La Jolla, California, USA. [2] Department of Medicine, University of California, San Diego, La Jolla, California, USA. [3] Department of Computer Science and Engineering, University of California, San Diego, La Jolla, California, USA. [4] Moores Cancer Center, University of California, San Diego, La Jolla, California, USA.

View Article
September 2014

A probabilistic model to predict clinical phenotypic traits from genome sequencing.

PLoS Comput Biol 2014 Sep 4;10(9):e1003825. Epub 2014 Sep 4.

Department of Biomedical Engineering and Institute for Computational Medicine, The Johns Hopkins University, Baltimore, Maryland, United States of America.

View Article
September 2014

Predicting the functional consequences of somatic missense mutations found in tumors.

Methods Mol Biol 2014 ;1101:135-59

Department of Medicine, University of California San Diego, La Jolla, CA, USA.

View Article
June 2014

Genotype to phenotype via network analysis.

Curr Opin Genet Dev 2013 Dec 14;23(6):611-21. Epub 2013 Nov 14.

Institute for Genomic Medicine and Department of Medicine, University of California, San Diego, 9500 Gillman Drive, La Jolla, CA 92093, United States.

View Article
December 2013

Network-based stratification of tumor mutations.

Nat Methods 2013 Nov 15;10(11):1108-15. Epub 2013 Sep 15.

Department of Computer Science and Engineering, University of California, San Diego, La Jolla, California, USA.

View Article
November 2013

Identifying Mendelian disease genes with the variant effect scoring tool.

BMC Genomics 2013 28;14 Suppl 3:S3. Epub 2013 May 28.

Department of Biomedical Engineering and Institute for Computational Medicine, Johns Hopkins University, 3400 N, Charles St, Baltimore, Maryland USA.

View Article
October 2013

A hybrid likelihood model for sequence-based disease association studies.

PLoS Genet 2013 24;9(1):e1003224. Epub 2013 Jan 24.

Department of Biomedical Engineering and Institute for Computational Medicine, Johns Hopkins University, Baltimore, Maryland, USA.

View Article
May 2013

CRAVAT: cancer-related analysis of variants toolkit.

Bioinformatics 2013 Mar 16;29(5):647-8. Epub 2013 Jan 16.

Department of Biomedical Engineering, Institute for Computational Medicine, Johns Hopkins University, Baltimore, MD 21218, USA.

View Article
March 2013

Somatic mutations in the Notch, NF-KB, PIK3CA, and Hedgehog pathways in human breast cancers.

Genes Chromosomes Cancer 2012 May 3;51(5):480-9. Epub 2012 Feb 3.

Science for Life Laboratory, Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.

View Article
May 2012

CHASM and SNVBox: toolkit for detecting biologically important single nucleotide mutations in cancer.

Bioinformatics 2011 Aug 17;27(15):2147-8. Epub 2011 Jun 17.

Department of Biomedical Engineering and Institute for Computational Medicine, Johns Hopkins University, Baltimore, MD, USA.

View Article
August 2011

Accumulation of driver and passenger mutations during tumor progression.

Proc Natl Acad Sci U S A 2010 Oct 27;107(43):18545-50. Epub 2010 Sep 27.

Program for Evolutionary Dynamics, Harvard University, Cambridge, MA 02138, USA.

View Article
October 2010

Prioritization of driver mutations in pancreatic cancer using cancer-specific high-throughput annotation of somatic mutations (CHASM).

Cancer Biol Ther 2010 Sep 1;10(6):582-7. Epub 2010 Oct 1.

Department of Biomedical Engineering and Institute for Computational Medicine, The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins Kimmel Cancer Center, Baltimore, MD, USA.

View Article
September 2010

Cancer-specific high-throughput annotation of somatic mutations: computational prediction of driver missense mutations.

Cancer Res 2009 Aug 4;69(16):6660-7. Epub 2009 Aug 4.

Department of Biomedical Engineering and Institute for Computational Medicine, Johns Hopkins University, Baltimore, Maryland 21218, USA.

View Article
August 2009

MODBASE, a database of annotated comparative protein structure models and associated resources.

Nucleic Acids Res 2009 Jan 23;37(Database issue):D347-54. Epub 2008 Oct 23.

Department of Bioengineering and Therapeutic Sciences, Department of Pharmaceutical Chemistry, University of California at San Francisco, 1700 4th Street, San Francisco, CA 94158, USA.

View Article
January 2009