Publications by authors named "Hanna E Abboud"

100Publications

Interplay between RNA-binding protein HuR and Nox4 as a novel therapeutic target in diabetic kidney disease.

Mol Metab 2020 Jun 28;36:100968. Epub 2020 Feb 28.

Department of Medicine/Division of Nephrology, Long School of Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.

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http://dx.doi.org/10.1016/j.molmet.2020.02.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115155PMC
June 2020

Nox4 is a Target for Tuberin Deficiency Syndrome.

Sci Rep 2018 02 28;8(1):3781. Epub 2018 Feb 28.

Departments of Medicine/Division of Nephrology, University of Texas Health San Antonio, San Antonio, Texas, USA.

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http://dx.doi.org/10.1038/s41598-018-21838-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830489PMC
February 2018

Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.

Authors:
Jason Flannick Christian Fuchsberger Anubha Mahajan Tanya M Teslovich Vineeta Agarwala Kyle J Gaulton Lizz Caulkins Ryan Koesterer Clement Ma Loukas Moutsianas Davis J McCarthy Manuel A Rivas John R B Perry Xueling Sim Thomas W Blackwell Neil R Robertson N William Rayner Pablo Cingolani Adam E Locke Juan Fernandez Tajes Heather M Highland Josee Dupuis Peter S Chines Cecilia M Lindgren Christopher Hartl Anne U Jackson Han Chen Jeroen R Huyghe Martijn van de Bunt Richard D Pearson Ashish Kumar Martina Müller-Nurasyid Niels Grarup Heather M Stringham Eric R Gamazon Jaehoon Lee Yuhui Chen Robert A Scott Jennifer E Below Peng Chen Jinyan Huang Min Jin Go Michael L Stitzel Dorota Pasko Stephen C J Parker Tibor V Varga Todd Green Nicola L Beer Aaron G Day-Williams Teresa Ferreira Tasha Fingerlin Momoko Horikoshi Cheng Hu Iksoo Huh Mohammad Kamran Ikram Bong-Jo Kim Yongkang Kim Young Jin Kim Min-Seok Kwon Juyoung Lee Selyeong Lee Keng-Han Lin Taylor J Maxwell Yoshihiko Nagai Xu Wang Ryan P Welch Joon Yoon Weihua Zhang Nir Barzilai Benjamin F Voight Bok-Ghee Han Christopher P Jenkinson Teemu Kuulasmaa Johanna Kuusisto Alisa Manning Maggie C Y Ng Nicholette D Palmer Beverley Balkau Alena Stančáková Hanna E Abboud Heiner Boeing Vilmantas Giedraitis Dorairaj Prabhakaran Omri Gottesman James Scott Jason Carey Phoenix Kwan George Grant Joshua D Smith Benjamin M Neale Shaun Purcell Adam S Butterworth Joanna M M Howson Heung Man Lee Yingchang Lu Soo-Heon Kwak Wei Zhao John Danesh Vincent K L Lam Kyong Soo Park Danish Saleheen Wing Yee So Claudia H T Tam Uzma Afzal David Aguilar Rector Arya Tin Aung Edmund Chan Carmen Navarro Ching-Yu Cheng Domenico Palli Adolfo Correa Joanne E Curran Dennis Rybin Vidya S Farook Sharon P Fowler Barry I Freedman Michael Griswold Daniel Esten Hale Pamela J Hicks Chiea-Chuen Khor Satish Kumar Benjamin Lehne Dorothée Thuillier Wei Yen Lim Jianjun Liu Marie Loh Solomon K Musani Sobha Puppala William R Scott Loïc Yengo Sian-Tsung Tan Herman A Taylor Farook Thameem Gregory Wilson Tien Yin Wong Pål Rasmus Njølstad Jonathan C Levy Massimo Mangino Lori L Bonnycastle Thomas Schwarzmayr João Fadista Gabriela L Surdulescu Christian Herder Christopher J Groves Thomas Wieland Jette Bork-Jensen Ivan Brandslund Cramer Christensen Heikki A Koistinen Alex S F Doney Leena Kinnunen Tõnu Esko Andrew J Farmer Liisa Hakaste Dylan Hodgkiss Jasmina Kravic Valeri Lyssenko Mette Hollensted Marit E Jørgensen Torben Jørgensen Claes Ladenvall Johanne Marie Justesen Annemari Käräjämäki Jennifer Kriebel Wolfgang Rathmann Lars Lannfelt Torsten Lauritzen Narisu Narisu Allan Linneberg Olle Melander Lili Milani Matt Neville Marju Orho-Melander Lu Qi Qibin Qi Michael Roden Olov Rolandsson Amy Swift Anders H Rosengren Kathleen Stirrups Andrew R Wood Evelin Mihailov Christine Blancher Mauricio O Carneiro Jared Maguire Ryan Poplin Khalid Shakir Timothy Fennell Mark DePristo Martin Hrabé de Angelis Panos Deloukas Anette P Gjesing Goo Jun Peter Nilsson Jacquelyn Murphy Robert Onofrio Barbara Thorand Torben Hansen Christa Meisinger Frank B Hu Bo Isomaa Fredrik Karpe Liming Liang Annette Peters Cornelia Huth Stephen P O'Rahilly Colin N A Palmer Oluf Pedersen Rainer Rauramaa Jaakko Tuomilehto Veikko Salomaa Richard M Watanabe Ann-Christine Syvänen Richard N Bergman Dwaipayan Bharadwaj Erwin P Bottinger Yoon Shin Cho Giriraj R Chandak Juliana C N Chan Kee Seng Chia Mark J Daly Shah B Ebrahim Claudia Langenberg Paul Elliott Kathleen A Jablonski Donna M Lehman Weiping Jia Ronald C W Ma Toni I Pollin Manjinder Sandhu Nikhil Tandon Philippe Froguel Inês Barroso Yik Ying Teo Eleftheria Zeggini Ruth J F Loos Kerrin S Small Janina S Ried Ralph A DeFronzo Harald Grallert Benjamin Glaser Andres Metspalu Nicholas J Wareham Mark Walker Eric Banks Christian Gieger Erik Ingelsson Hae Kyung Im Thomas Illig Paul W Franks Gemma Buck Joseph Trakalo David Buck Inga Prokopenko Reedik Mägi Lars Lind Yossi Farjoun Katharine R Owen Anna L Gloyn Konstantin Strauch Tiinamaija Tuomi Jaspal Singh Kooner Jong-Young Lee Taesung Park Peter Donnelly Andrew D Morris Andrew T Hattersley Donald W Bowden Francis S Collins Gil Atzmon John C Chambers Timothy D Spector Markku Laakso Tim M Strom Graeme I Bell John Blangero Ravindranath Duggirala E Shyong Tai Gilean McVean Craig L Hanis James G Wilson Mark Seielstad Timothy M Frayling James B Meigs Nancy J Cox Rob Sladek Eric S Lander Stacey Gabriel Karen L Mohlke Thomas Meitinger Leif Groop Goncalo Abecasis Laura J Scott Andrew P Morris Hyun Min Kang David Altshuler Noël P Burtt Jose C Florez Michael Boehnke Mark I McCarthy

Sci Data 2018 01 23;5:180002. Epub 2018 Jan 23.

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http://dx.doi.org/10.1038/sdata.2018.2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779067PMC
January 2018

Mouse Metanephric Mesenchymal Cell-Derived Angioblasts Undergo Vasculogenesis in Three-Dimensional Culture.

Am J Pathol 2018 03 19;188(3):768-784. Epub 2017 Dec 19.

Department of Medicine, Division of Nephrology, Audie Murphy Memorial Veterans Administration Hospital, South Texas Veterans Health Care System, San Antonio, Texas; Probetex, Inc., San Antonio, Texas; The Medical Research Service, Audie Murphy Memorial Veterans Administration Hospital, South Texas Veterans Health Care System, San Antonio, Texas. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00029440173058
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http://dx.doi.org/10.1016/j.ajpath.2017.10.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840483PMC
March 2018

Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.

Authors:
Jason Flannick Christian Fuchsberger Anubha Mahajan Tanya M Teslovich Vineeta Agarwala Kyle J Gaulton Lizz Caulkins Ryan Koesterer Clement Ma Loukas Moutsianas Davis J McCarthy Manuel A Rivas John R B Perry Xueling Sim Thomas W Blackwell Neil R Robertson N William Rayner Pablo Cingolani Adam E Locke Juan Fernandez Tajes Heather M Highland Josee Dupuis Peter S Chines Cecilia M Lindgren Christopher Hartl Anne U Jackson Han Chen Jeroen R Huyghe Martijn van de Bunt Richard D Pearson Ashish Kumar Martina Müller-Nurasyid Niels Grarup Heather M Stringham Eric R Gamazon Jaehoon Lee Yuhui Chen Robert A Scott Jennifer E Below Peng Chen Jinyan Huang Min Jin Go Michael L Stitzel Dorota Pasko Stephen C J Parker Tibor V Varga Todd Green Nicola L Beer Aaron G Day-Williams Teresa Ferreira Tasha Fingerlin Momoko Horikoshi Cheng Hu Iksoo Huh Mohammad Kamran Ikram Bong-Jo Kim Yongkang Kim Young Jin Kim Min-Seok Kwon Juyoung Lee Selyeong Lee Keng-Han Lin Taylor J Maxwell Yoshihiko Nagai Xu Wang Ryan P Welch Joon Yoon Weihua Zhang Nir Barzilai Benjamin F Voight Bok-Ghee Han Christopher P Jenkinson Teemu Kuulasmaa Johanna Kuusisto Alisa Manning Maggie C Y Ng Nicholette D Palmer Beverley Balkau Alena Stančáková Hanna E Abboud Heiner Boeing Vilmantas Giedraitis Dorairaj Prabhakaran Omri Gottesman James Scott Jason Carey Phoenix Kwan George Grant Joshua D Smith Benjamin M Neale Shaun Purcell Adam S Butterworth Joanna M M Howson Heung Man Lee Yingchang Lu Soo-Heon Kwak Wei Zhao John Danesh Vincent K L Lam Kyong Soo Park Danish Saleheen Wing Yee So Claudia H T Tam Uzma Afzal David Aguilar Rector Arya Tin Aung Edmund Chan Carmen Navarro Ching-Yu Cheng Domenico Palli Adolfo Correa Joanne E Curran Dennis Rybin Vidya S Farook Sharon P Fowler Barry I Freedman Michael Griswold Daniel Esten Hale Pamela J Hicks Chiea-Chuen Khor Satish Kumar Benjamin Lehne Dorothée Thuillier Wei Yen Lim Jianjun Liu Marie Loh Solomon K Musani Sobha Puppala William R Scott Loïc Yengo Sian-Tsung Tan Herman A Taylor Farook Thameem Gregory Wilson Tien Yin Wong Pål Rasmus Njølstad Jonathan C Levy Massimo Mangino Lori L Bonnycastle Thomas Schwarzmayr João Fadista Gabriela L Surdulescu Christian Herder Christopher J Groves Thomas Wieland Jette Bork-Jensen Ivan Brandslund Cramer Christensen Heikki A Koistinen Alex S F Doney Leena Kinnunen Tõnu Esko Andrew J Farmer Liisa Hakaste Dylan Hodgkiss Jasmina Kravic Valeri Lyssenko Mette Hollensted Marit E Jørgensen Torben Jørgensen Claes Ladenvall Johanne Marie Justesen Annemari Käräjämäki Jennifer Kriebel Wolfgang Rathmann Lars Lannfelt Torsten Lauritzen Narisu Narisu Allan Linneberg Olle Melander Lili Milani Matt Neville Marju Orho-Melander Lu Qi Qibin Qi Michael Roden Olov Rolandsson Amy Swift Anders H Rosengren Kathleen Stirrups Andrew R Wood Evelin Mihailov Christine Blancher Mauricio O Carneiro Jared Maguire Ryan Poplin Khalid Shakir Timothy Fennell Mark DePristo Martin Hrabé de Angelis Panos Deloukas Anette P Gjesing Goo Jun Peter Nilsson Jacquelyn Murphy Robert Onofrio Barbara Thorand Torben Hansen Christa Meisinger Frank B Hu Bo Isomaa Fredrik Karpe Liming Liang Annette Peters Cornelia Huth Stephen P O'Rahilly Colin N A Palmer Oluf Pedersen Rainer Rauramaa Jaakko Tuomilehto Veikko Salomaa Richard M Watanabe Ann-Christine Syvänen Richard N Bergman Dwaipayan Bharadwaj Erwin P Bottinger Yoon Shin Cho Giriraj R Chandak Juliana Cn Chan Kee Seng Chia Mark J Daly Shah B Ebrahim Claudia Langenberg Paul Elliott Kathleen A Jablonski Donna M Lehman Weiping Jia Ronald C W Ma Toni I Pollin Manjinder Sandhu Nikhil Tandon Philippe Froguel Inês Barroso Yik Ying Teo Eleftheria Zeggini Ruth J F Loos Kerrin S Small Janina S Ried Ralph A DeFronzo Harald Grallert Benjamin Glaser Andres Metspalu Nicholas J Wareham Mark Walker Eric Banks Christian Gieger Erik Ingelsson Hae Kyung Im Thomas Illig Paul W Franks Gemma Buck Joseph Trakalo David Buck Inga Prokopenko Reedik Mägi Lars Lind Yossi Farjoun Katharine R Owen Anna L Gloyn Konstantin Strauch Tiinamaija Tuomi Jaspal Singh Kooner Jong-Young Lee Taesung Park Peter Donnelly Andrew D Morris Andrew T Hattersley Donald W Bowden Francis S Collins Gil Atzmon John C Chambers Timothy D Spector Markku Laakso Tim M Strom Graeme I Bell John Blangero Ravindranath Duggirala E Shyong Tai Gilean McVean Craig L Hanis James G Wilson Mark Seielstad Timothy M Frayling James B Meigs Nancy J Cox Rob Sladek Eric S Lander Stacey Gabriel Karen L Mohlke Thomas Meitinger Leif Groop Goncalo Abecasis Laura J Scott Andrew P Morris Hyun Min Kang David Altshuler Noël P Burtt Jose C Florez Michael Boehnke Mark I McCarthy

Sci Data 2017 12 19;4:170179. Epub 2017 Dec 19.

Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1038/sdata.2017.179DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735917PMC
December 2017

A Loss-of-Function Splice Acceptor Variant in Is Protective for Type 2 Diabetes.

Diabetes 2017 11 24;66(11):2903-2914. Epub 2017 Aug 24.

Broad Metabolism Program and Program in Medical and Population Genetics, Broad Institute, Cambridge, MA

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http://dx.doi.org/10.2337/db17-0187DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652606PMC
November 2017

Tryptophan Metabolism in Patients With Chronic Kidney Disease Secondary to Type 2 Diabetes: Relationship to Inflammatory Markers.

Int J Tryptophan Res 2017 10;10:1178646917694600. Epub 2017 Mar 10.

Department of Pharmacology, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.

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http://dx.doi.org/10.1177/1178646917694600DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398653PMC
March 2017

A Low-Frequency Inactivating Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk.

Authors:
Alisa Manning Heather M Highland Jessica Gasser Xueling Sim Taru Tukiainen Pierre Fontanillas Niels Grarup Manuel A Rivas Anubha Mahajan Adam E Locke Pablo Cingolani Tune H Pers Ana Viñuela Andrew A Brown Ying Wu Jason Flannick Christian Fuchsberger Eric R Gamazon Kyle J Gaulton Hae Kyung Im Tanya M Teslovich Thomas W Blackwell Jette Bork-Jensen Noël P Burtt Yuhui Chen Todd Green Christopher Hartl Hyun Min Kang Ashish Kumar Claes Ladenvall Clement Ma Loukas Moutsianas Richard D Pearson John R B Perry N William Rayner Neil R Robertson Laura J Scott Martijn van de Bunt Johan G Eriksson Antti Jula Seppo Koskinen Terho Lehtimäki Aarno Palotie Olli T Raitakari Suzanne B R Jacobs Jennifer Wessel Audrey Y Chu Robert A Scott Mark O Goodarzi Christine Blancher Gemma Buck David Buck Peter S Chines Stacey Gabriel Anette P Gjesing Christopher J Groves Mette Hollensted Jeroen R Huyghe Anne U Jackson Goo Jun Johanne Marie Justesen Massimo Mangino Jacquelyn Murphy Matt Neville Robert Onofrio Kerrin S Small Heather M Stringham Joseph Trakalo Eric Banks Jason Carey Mauricio O Carneiro Mark DePristo Yossi Farjoun Timothy Fennell Jacqueline I Goldstein George Grant Martin Hrabé de Angelis Jared Maguire Benjamin M Neale Ryan Poplin Shaun Purcell Thomas Schwarzmayr Khalid Shakir Joshua D Smith Tim M Strom Thomas Wieland Jaana Lindstrom Ivan Brandslund Cramer Christensen Gabriela L Surdulescu Timo A Lakka Alex S F Doney Peter Nilsson Nicholas J Wareham Claudia Langenberg Tibor V Varga Paul W Franks Olov Rolandsson Anders H Rosengren Vidya S Farook Farook Thameem Sobha Puppala Satish Kumar Donna M Lehman Christopher P Jenkinson Joanne E Curran Daniel Esten Hale Sharon P Fowler Rector Arya Ralph A DeFronzo Hanna E Abboud Ann-Christine Syvänen Pamela J Hicks Nicholette D Palmer Maggie C Y Ng Donald W Bowden Barry I Freedman Tõnu Esko Reedik Mägi Lili Milani Evelin Mihailov Andres Metspalu Narisu Narisu Leena Kinnunen Lori L Bonnycastle Amy Swift Dorota Pasko Andrew R Wood João Fadista Toni I Pollin Nir Barzilai Gil Atzmon Benjamin Glaser Barbara Thorand Konstantin Strauch Annette Peters Michael Roden Martina Müller-Nurasyid Liming Liang Jennifer Kriebel Thomas Illig Harald Grallert Christian Gieger Christa Meisinger Lars Lannfelt Solomon K Musani Michael Griswold Herman A Taylor Gregory Wilson Adolfo Correa Heikki Oksa William R Scott Uzma Afzal Sian-Tsung Tan Marie Loh John C Chambers Jobanpreet Sehmi Jaspal Singh Kooner Benjamin Lehne Yoon Shin Cho Jong-Young Lee Bok-Ghee Han Annemari Käräjämäki Qibin Qi Lu Qi Jinyan Huang Frank B Hu Olle Melander Marju Orho-Melander Jennifer E Below David Aguilar Tien Yin Wong Jianjun Liu Chiea-Chuen Khor Kee Seng Chia Wei Yen Lim Ching-Yu Cheng Edmund Chan E Shyong Tai Tin Aung Allan Linneberg Bo Isomaa Thomas Meitinger Tiinamaija Tuomi Liisa Hakaste Jasmina Kravic Marit E Jørgensen Torsten Lauritzen Panos Deloukas Kathleen E Stirrups Katharine R Owen Andrew J Farmer Timothy M Frayling Stephen P O'Rahilly Mark Walker Jonathan C Levy Dylan Hodgkiss Andrew T Hattersley Teemu Kuulasmaa Alena Stančáková Inês Barroso Dwaipayan Bharadwaj Juliana Chan Giriraj R Chandak Mark J Daly Peter J Donnelly Shah B Ebrahim Paul Elliott Tasha Fingerlin Philippe Froguel Cheng Hu Weiping Jia Ronald C W Ma Gilean McVean Taesung Park Dorairaj Prabhakaran Manjinder Sandhu James Scott Rob Sladek Nikhil Tandon Yik Ying Teo Eleftheria Zeggini Richard M Watanabe Heikki A Koistinen Y Antero Kesaniemi Matti Uusitupa Timothy D Spector Veikko Salomaa Rainer Rauramaa Colin N A Palmer Inga Prokopenko Andrew D Morris Richard N Bergman Francis S Collins Lars Lind Erik Ingelsson Jaakko Tuomilehto Fredrik Karpe Leif Groop Torben Jørgensen Torben Hansen Oluf Pedersen Johanna Kuusisto Gonçalo Abecasis Graeme I Bell John Blangero Nancy J Cox Ravindranath Duggirala Mark Seielstad James G Wilson Josee Dupuis Samuli Ripatti Craig L Hanis Jose C Florez Karen L Mohlke James B Meigs Markku Laakso Andrew P Morris Michael Boehnke David Altshuler Mark I McCarthy Anna L Gloyn Cecilia M Lindgren

Diabetes 2017 07 24;66(7):2019-2032. Epub 2017 Mar 24.

Program in Medical and Population Genetics, Broad Institute, Cambridge, MA.

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http://dx.doi.org/10.2337/db16-1329DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482074PMC
July 2017

mTORC2 Signaling Regulates Nox4-Induced Podocyte Depletion in Diabetes.

Antioxid Redox Signal 2016 11 12;25(13):703-719. Epub 2016 Sep 12.

1 Department of Anatomy, Cell Biology and Physiological Sciences, Faculty of Medicine and Medical Center, American University of Beirut , Beirut, Lebanon .

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http://dx.doi.org/10.1089/ars.2015.6562DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079418PMC
November 2016

Genetic Variants in Toll-Like Receptor 4 Gene and Their Association Analysis with Estimated Glomerular Filtration Rate in Mexican American Families.

Cardiorenal Med 2016 Aug 20;6(4):301-6. Epub 2016 May 20.

Division of Nephrology, Department of Medicine, University of Texas Health Science Center, San Antonio, Tex, USA; South Texas Veterans Healthcare System, San Antonio, Tex, USA.

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http://dx.doi.org/10.1159/000445754DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020380PMC
August 2016

The genetic architecture of type 2 diabetes.

Authors:
Christian Fuchsberger Jason Flannick Tanya M Teslovich Anubha Mahajan Vineeta Agarwala Kyle J Gaulton Clement Ma Pierre Fontanillas Loukas Moutsianas Davis J McCarthy Manuel A Rivas John R B Perry Xueling Sim Thomas W Blackwell Neil R Robertson N William Rayner Pablo Cingolani Adam E Locke Juan Fernandez Tajes Heather M Highland Josee Dupuis Peter S Chines Cecilia M Lindgren Christopher Hartl Anne U Jackson Han Chen Jeroen R Huyghe Martijn van de Bunt Richard D Pearson Ashish Kumar Martina Müller-Nurasyid Niels Grarup Heather M Stringham Eric R Gamazon Jaehoon Lee Yuhui Chen Robert A Scott Jennifer E Below Peng Chen Jinyan Huang Min Jin Go Michael L Stitzel Dorota Pasko Stephen C J Parker Tibor V Varga Todd Green Nicola L Beer Aaron G Day-Williams Teresa Ferreira Tasha Fingerlin Momoko Horikoshi Cheng Hu Iksoo Huh Mohammad Kamran Ikram Bong-Jo Kim Yongkang Kim Young Jin Kim Min-Seok Kwon Juyoung Lee Selyeong Lee Keng-Han Lin Taylor J Maxwell Yoshihiko Nagai Xu Wang Ryan P Welch Joon Yoon Weihua Zhang Nir Barzilai Benjamin F Voight Bok-Ghee Han Christopher P Jenkinson Teemu Kuulasmaa Johanna Kuusisto Alisa Manning Maggie C Y Ng Nicholette D Palmer Beverley Balkau Alena Stančáková Hanna E Abboud Heiner Boeing Vilmantas Giedraitis Dorairaj Prabhakaran Omri Gottesman James Scott Jason Carey Phoenix Kwan George Grant Joshua D Smith Benjamin M Neale Shaun Purcell Adam S Butterworth Joanna M M Howson Heung Man Lee Yingchang Lu Soo-Heon Kwak Wei Zhao John Danesh Vincent K L Lam Kyong Soo Park Danish Saleheen Wing Yee So Claudia H T Tam Uzma Afzal David Aguilar Rector Arya Tin Aung Edmund Chan Carmen Navarro Ching-Yu Cheng Domenico Palli Adolfo Correa Joanne E Curran Denis Rybin Vidya S Farook Sharon P Fowler Barry I Freedman Michael Griswold Daniel Esten Hale Pamela J Hicks Chiea-Chuen Khor Satish Kumar Benjamin Lehne Dorothée Thuillier Wei Yen Lim Jianjun Liu Yvonne T van der Schouw Marie Loh Solomon K Musani Sobha Puppala William R Scott Loïc Yengo Sian-Tsung Tan Herman A Taylor Farook Thameem Gregory Wilson Tien Yin Wong Pål Rasmus Njølstad Jonathan C Levy Massimo Mangino Lori L Bonnycastle Thomas Schwarzmayr João Fadista Gabriela L Surdulescu Christian Herder Christopher J Groves Thomas Wieland Jette Bork-Jensen Ivan Brandslund Cramer Christensen Heikki A Koistinen Alex S F Doney Leena Kinnunen Tõnu Esko Andrew J Farmer Liisa Hakaste Dylan Hodgkiss Jasmina Kravic Valeriya Lyssenko Mette Hollensted Marit E Jørgensen Torben Jørgensen Claes Ladenvall Johanne Marie Justesen Annemari Käräjämäki Jennifer Kriebel Wolfgang Rathmann Lars Lannfelt Torsten Lauritzen Narisu Narisu Allan Linneberg Olle Melander Lili Milani Matt Neville Marju Orho-Melander Lu Qi Qibin Qi Michael Roden Olov Rolandsson Amy Swift Anders H Rosengren Kathleen Stirrups Andrew R Wood Evelin Mihailov Christine Blancher Mauricio O Carneiro Jared Maguire Ryan Poplin Khalid Shakir Timothy Fennell Mark DePristo Martin Hrabé de Angelis Panos Deloukas Anette P Gjesing Goo Jun Peter Nilsson Jacquelyn Murphy Robert Onofrio Barbara Thorand Torben Hansen Christa Meisinger Frank B Hu Bo Isomaa Fredrik Karpe Liming Liang Annette Peters Cornelia Huth Stephen P O'Rahilly Colin N A Palmer Oluf Pedersen Rainer Rauramaa Jaakko Tuomilehto Veikko Salomaa Richard M Watanabe Ann-Christine Syvänen Richard N Bergman Dwaipayan Bharadwaj Erwin P Bottinger Yoon Shin Cho Giriraj R Chandak Juliana C N Chan Kee Seng Chia Mark J Daly Shah B Ebrahim Claudia Langenberg Paul Elliott Kathleen A Jablonski Donna M Lehman Weiping Jia Ronald C W Ma Toni I Pollin Manjinder Sandhu Nikhil Tandon Philippe Froguel Inês Barroso Yik Ying Teo Eleftheria Zeggini Ruth J F Loos Kerrin S Small Janina S Ried Ralph A DeFronzo Harald Grallert Benjamin Glaser Andres Metspalu Nicholas J Wareham Mark Walker Eric Banks Christian Gieger Erik Ingelsson Hae Kyung Im Thomas Illig Paul W Franks Gemma Buck Joseph Trakalo David Buck Inga Prokopenko Reedik Mägi Lars Lind Yossi Farjoun Katharine R Owen Anna L Gloyn Konstantin Strauch Tiinamaija Tuomi Jaspal Singh Kooner Jong-Young Lee Taesung Park Peter Donnelly Andrew D Morris Andrew T Hattersley Donald W Bowden Francis S Collins Gil Atzmon John C Chambers Timothy D Spector Markku Laakso Tim M Strom Graeme I Bell John Blangero Ravindranath Duggirala E Shyong Tai Gilean McVean Craig L Hanis James G Wilson Mark Seielstad Timothy M Frayling James B Meigs Nancy J Cox Rob Sladek Eric S Lander Stacey Gabriel Noël P Burtt Karen L Mohlke Thomas Meitinger Leif Groop Goncalo Abecasis Jose C Florez Laura J Scott Andrew P Morris Hyun Min Kang Michael Boehnke David Altshuler Mark I McCarthy

Nature 2016 08 11;536(7614):41-47. Epub 2016 Jul 11.

Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.

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http://hmg.oxfordjournals.org/content/early/2015/07/21/hmg.d
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http://www.nature.com/doifinder/10.1038/nature18642
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http://dx.doi.org/10.1038/nature18642DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034897PMC
August 2016

Tuberin regulates reactive oxygen species in renal proximal cells, kidney from rodents, and kidney from patients with tuberous sclerosis complex.

Cancer Sci 2016 Aug 25;107(8):1092-100. Epub 2016 Jul 25.

Geriatric Research, Education and Clinical Department, South Texas Veterans Health Care System, San Antonio, Texas, USA.

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http://dx.doi.org/10.1111/cas.12984DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982584PMC
August 2016

Layer-Specific Manganese-Enhanced MRI of the Diabetic Rat Retina in Light and Dark Adaptation at 11.7 Tesla.

Invest Ophthalmol Vis Sci 2015 Jun;56(6):4006-12

Research Imaging Institute, University of Texas Health Science Center, San Antonio, Texas, United States 2Departments of Ophthalmology, Radiology, and Physiology, University of Texas Health Science Center, San Antonio, Texas, United States 4South Texas Ve.

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http://iovs.arvojournals.org/article.aspx?doi=10.1167/iovs.1
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http://dx.doi.org/10.1167/iovs.14-16128DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477260PMC
June 2015

Activation of AMP-activated protein kinase prevents TGF-β1-induced epithelial-mesenchymal transition and myofibroblast activation.

Am J Pathol 2015 Aug 10;185(8):2168-80. Epub 2015 Jun 10.

Department of Medicine, University of Texas Health Science Center, San Antonio, Texas; Audie L. Murphy Memorial Hospital Division, South Texas Veterans Healthcare System, San Antonio, Texas.

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http://dx.doi.org/10.1016/j.ajpath.2015.04.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530134PMC
August 2015

Metformin prevents renal interstitial fibrosis in mice with unilateral ureteral obstruction.

Mol Cell Endocrinol 2015 Sep 9;412:116-22. Epub 2015 Jun 9.

Department of Medicine/Nephrology, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.

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http://dx.doi.org/10.1016/j.mce.2015.06.006DOI Listing
September 2015

Nox2 mediates skeletal muscle insulin resistance induced by a high fat diet.

J Biol Chem 2015 May 30;290(21):13427-39. Epub 2015 Mar 30.

From the Department of Medicine, University of Texas Health Science Center, San Antonio, Texas 78229-3900,

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http://dx.doi.org/10.1074/jbc.M114.626077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505590PMC
May 2015

Targeting NADPH oxidase with a novel dual Nox1/Nox4 inhibitor attenuates renal pathology in type 1 diabetes.

Am J Physiol Renal Physiol 2015 Jun 4;308(11):F1276-87. Epub 2015 Feb 4.

Department of Medicine, The University of Texas Health Science Center, San Antonio, Texas; Audie Leon Murphy Memorial Hospital Division, South Texas Veterans Health Care System, San Antonio, Texas; and.

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http://www.physiology.org/doi/10.1152/ajprenal.00396.2014
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http://dx.doi.org/10.1152/ajprenal.00396.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451325PMC
June 2015

NADPH oxidase 4 induces cardiac fibrosis and hypertrophy through activating Akt/mTOR and NFκB signaling pathways.

Circulation 2015 Feb 14;131(7):643-55. Epub 2015 Jan 14.

From the Department of Medicine, University of Texas Health Science Center and South Texas Veterans Health Care System, San Antonio, TX.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.114.011079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568756PMC
February 2015

TGFβ-induced deptor suppression recruits mTORC1 and not mTORC2 to enhance collagen I (α2) gene expression.

PLoS One 2014 15;9(10):e109608. Epub 2014 Oct 15.

Departments of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America; Geriatric Research, Education and Clinical Center, South Texas Veterans Health Care System, San Antonio, Texas, United States of America; VA Research, South Texas Veterans Health Care System, San Antonio, Texas, United States of America.

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June 2015

microRNA-21-induced dissociation of PDCD4 from rictor contributes to Akt-IKKβ-mTORC1 axis to regulate renal cancer cell invasion.

Exp Cell Res 2014 Oct 9;328(1):99-117. Epub 2014 Jul 9.

Veterans Administration Research Service, South Texas Veterans Health Care System, San Antonio, TX, USA; Department of Medicine, University of Texas Health Science Center at San Antonio, TX, USA; Geriatric Research, Education and Clinical Center, South Texas Veterans Health Care System, San Antonio, TX, USA. Electronic address:

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October 2014

ADAM17 promotes proliferation of collecting duct kidney epithelial cells through ERK activation and increased glycolysis in polycystic kidney disease.

Am J Physiol Renal Physiol 2014 Sep 4;307(5):F551-9. Epub 2014 Jun 4.

Division of Nephrology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina; Ralph H. Johnson Veterans Affairs Medical Center, Charleston, South Carolina.

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September 2014

A positive feedback loop involving Erk5 and Akt turns on mesangial cell proliferation in response to PDGF.

Am J Physiol Cell Physiol 2014 Jun 16;306(11):C1089-100. Epub 2014 Apr 16.

Veterans Administration Research Service, South Texas Veterans Health Care System, San Antonio, Texas; Department of Medicine, University of Texas Health Science Center, San Antonio, Texas; and Geriatric Research, Education, and Clinical Center, South Texas Veterans Health Care System, San Antonio, Texas.

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June 2014

Susceptibility gene search for nephropathy and related traits in Mexican-Americans.

Mol Biol Rep 2013 Oct 22;40(10):5769-79. Epub 2013 Sep 22.

Division of Nephrology, Department of Medicine, The University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX, 78229, USA,

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October 2013

NFκB-mediated cyclin D1 expression by microRNA-21 influences renal cancer cell proliferation.

Cell Signal 2013 Dec 24;25(12):2575-86. Epub 2013 Aug 24.

Department of Medicine, University of Texas Health Science Center at San Antonio, TX, United States.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896302PMC
December 2013

The antioxidant silybin prevents high glucose-induced oxidative stress and podocyte injury in vitro and in vivo.

Am J Physiol Renal Physiol 2013 Sep 26;305(5):F691-700. Epub 2013 Jun 26.

Univ. of Texas Health Science Center, Dept. of Medicine, Division of Nephrology MC 7882, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900, USA.

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September 2013

Improving learning about familial risks using a multicomponent approach: the GRACE program.

Per Med 2013 Jan;10(1):35-44

Department of Medicine, University of Texas Health Science Center at San Antonio, South Texas Veterans Health Care System, San Antonio, TX, CP-210-827 5597, USA ; South Texas Veterans Health Care System/Audie L Murphy Memorial Veterans Hospital, San Antonio, TX, USA.

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January 2013

ADAM17 mediates Nox4 expression and NADPH oxidase activity in the kidney cortex of OVE26 mice.

Am J Physiol Renal Physiol 2013 Aug 15;305(3):F323-32. Epub 2013 May 15.

Department of Medicine, Division of Nephrology, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742865PMC
August 2013

Synthetic oleanane triterpenoids: magic bullets or not?

Authors:
Hanna E Abboud

Kidney Int 2013 May;83(5):785-7

Nephrology Division, University of Texas Health Sciences Center San Antonio, Texas, USA.

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May 2013

Mammalian target of rapamycin regulates Nox4-mediated podocyte depletion in diabetic renal injury.

Diabetes 2013 Aug 4;62(8):2935-47. Epub 2013 Apr 4.

Department of Medicine, South Texas Veterans Healthcare System and the University of Texas Health Science Center, San Antonio, Texas, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717863PMC
August 2013

Renal histopathology of a baboon model with type 2 diabetes.

Toxicol Pathol 2012 Oct 2;40(7):1020-30. Epub 2012 May 2.

Audie L Murphy Division, South Texas Veterans Health Care System, San Antonio, Texas, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477873PMC
October 2012

Diabetic nephropathy among Mexican Americans.

Clin Nephrol 2012 Apr;77(4):332-44

Division of Nephrology, University of Texas Health Science Center, San Antonio, TX, USA.

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http://dx.doi.org/10.5414/cn107487DOI Listing
April 2012

Mesangial cell biology.

Authors:
Hanna E Abboud

Exp Cell Res 2012 May 5;318(9):979-85. Epub 2012 Mar 5.

University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.

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May 2012

Prediabetic nephropathy as an early consequence of the high-calorie/high-fat diet: relation to oxidative stress.

Endocrinology 2012 Mar 10;153(3):1152-61. Epub 2012 Jan 10.

Pennington Biomedical Research Center, Louisiana State University, 6400 Perkins Road, Baton Rouge, Louisiana 70808, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281531PMC
March 2012

Reciprocal induction of simple organogenesis by mouse kidney progenitor cells in three-dimensional co-culture.

Am J Pathol 2012 Feb 2;180(2):819-30. Epub 2011 Dec 2.

Division of Nephrology, Department of Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229-3900, USA.

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http://dx.doi.org/10.1016/j.ajpath.2011.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349862PMC
February 2012

Veterans' experience in using the online Surgeon General's family health history tool.

Per Med 2011 Sep;8(5):523-532

Department of Medicine, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX78229, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210025PMC
September 2011

Nox4-derived reactive oxygen species mediate cardiomyocyte injury in early type 1 diabetes.

Am J Physiol Cell Physiol 2012 Feb 26;302(3):C597-604. Epub 2011 Oct 26.

Dept. of Medicine, Division of Cardiology, Univ. of Texas Health Science Center, San Antonio, TX 78229-3900, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814247PMC
February 2012

IGF-I increases the expression of fibronectin by Nox4-dependent Akt phosphorylation in renal tubular epithelial cells.

Am J Physiol Cell Physiol 2012 Jan 21;302(1):C122-30. Epub 2011 Sep 21.

University of Texas Health Science Center Department of Medicine, San Antonio, Texas 78229-3900, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328902PMC
January 2012

The 57 kb deletion in cystinosis patients extends into TRPV1 causing dysregulation of transcription in peripheral blood mononuclear cells.

J Med Genet 2011 Aug 5;48(8):563-6. Epub 2011 May 5.

Department of Genetics, Texas Biomedical Research Institute, San Antonio, TX 78245-0549, USA.

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August 2011

Abundance of TRPC6 protein in glomerular mesangial cells is decreased by ROS and PKC in diabetes.

Am J Physiol Cell Physiol 2011 Aug 27;301(2):C304-15. Epub 2011 Apr 27.

Department of Integrative Physiology and Cardiovascular Research Institute, University of North Texas Health Science Center, Fort Worth, TX 76107, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154551PMC
August 2011

Genetic variants in transient receptor potential cation channel, subfamily M 1 (TRPM1) and their risk of albuminuria-related traits in Mexican Americans.

Clin Chim Acta 2011 Nov 1;412(23-24):2058-62. Epub 2011 Apr 1.

Division of Nephrology, Department of Medicine, University of Texas Health Science Center, San Antonio, TX 78229, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206641PMC
November 2011

The tuberin/mTOR pathway promotes apoptosis of tubular epithelial cells in diabetes.

J Am Soc Nephrol 2011 Feb;22(2):262-73

The University of Texas Health Science Center, Department of Medicine-MSC 7882, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3029899PMC
February 2011

AMP-activated protein kinase (AMPK) negatively regulates Nox4-dependent activation of p53 and epithelial cell apoptosis in diabetes.

J Biol Chem 2010 Nov 22;285(48):37503-12. Epub 2010 Sep 22.

Department of Medicine, University of Texas Health Science Center, San Antonio, Texas 78229-3900, USA.

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http://dx.doi.org/10.1074/jbc.M110.136796DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988355PMC
November 2010

Novel mechanism of regulation of the DNA repair enzyme OGG1 in tuberin-deficient cells.

Carcinogenesis 2010 Nov 13;31(11):2022-30. Epub 2010 Sep 13.

Department of Geriatrics, Geriatric Research, Education, and Clinical Center, South Texas Veterans Healthcare System, San Antonio, TX 78229, USA.

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http://dx.doi.org/10.1093/carcin/bgq189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105579PMC
November 2010

Providers' behavioral beliefs regarding the delivery of genomic medicine at the Veterans Health Administration.

Per Med 2010 Sep;7(5):485-494

Division of Nephrology/Department of Medicine, University of Texas Health Science Center at San Antonio, Audie L Murphy Memorial Veterans Hospital, 7703 Floyd Curl Drive, San Antonio, TX, USA.

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September 2010

Examination of association with candidate genes for diabetic nephropathy in a Mexican American population.

Clin J Am Soc Nephrol 2010 Jun 18;5(6):1072-8. Epub 2010 Mar 18.

Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, Ohio, USA.

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http://dx.doi.org/10.2215/CJN.06550909DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879299PMC
June 2010

NAD(P)H oxidase mediates TGF-beta1-induced activation of kidney myofibroblasts.

J Am Soc Nephrol 2010 Jan 19;21(1):93-102. Epub 2009 Nov 19.

Department of Medicine, University of Texas Health Science Center, San Antonio, TX 78229-3900, USA.

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http://dx.doi.org/10.1681/ASN.2009020146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2799274PMC
January 2010

Subcellular localization of Nox4 and regulation in diabetes.

Proc Natl Acad Sci U S A 2009 Aug 17;106(34):14385-90. Epub 2009 Aug 17.

Department of Medicine, University of Texas Health Science Center, San Antonio, TX 78229, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0906805106
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2732863PMC
August 2009

TSC2 deficiency increases PTEN via HIF1alpha.

J Biol Chem 2009 Oct 31;284(41):27790-8. Epub 2009 Jul 31.

Department of Medicine, University of Texas Health Science Center, San Antonio, Texas 78229-3900, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788829PMC
October 2009

Evaluation of polymorphisms in paraoxonase 2 (PON2) gene and their association with cardiovascular-renal disease risk in Mexican Americans.

Kidney Blood Press Res 2009 18;32(3):200-4. Epub 2009 Jun 18.

Division of Nephrology, Department of Medicine, University of Texas Health Science Center, San Antonio, Tex., USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2759102PMC
December 2009

The 27-bp repeat polymorphism in intron 4 (27 bp-VNTR) of endothelial nitric oxide synthase (eNOS) gene is associated with albumin to creatinine ratio in Mexican Americans.

Mol Cell Biochem 2009 Nov 26;331(1-2):201-5. Epub 2009 May 26.

Division of Nephrology, Department of Medicine, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX, 78229, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428139PMC
November 2009

PDGF receptor-{beta} modulates metanephric mesenchyme chemotaxis induced by PDGF AA.

Am J Physiol Renal Physiol 2009 Feb 19;296(2):F406-17. Epub 2008 Nov 19.

Department of Molecular Medicine, Institute of Biotechnology, Univ. of Texas Health Science Center at San Antonio, San Antonio, TX 78229-3900, USA.

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http://dx.doi.org/10.1152/ajprenal.90368.2008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2643859PMC
February 2009

Genetics of variation in serum uric acid and cardiovascular risk factors in Mexican Americans.

J Clin Endocrinol Metab 2009 Feb 11;94(2):632-8. Epub 2008 Nov 11.

Department of Genetics, Southwest Foundation for Biomedical Research, P.O. Box 760549, San Antonio, Texas 78227, USA.

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http://dx.doi.org/10.1210/jc.2008-0682DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646516PMC
February 2009

Genetic variants in the renin-angiotensin system genes are associated with cardiovascular-renal-related risk factors in Mexican Americans.

Hum Genet 2008 Dec 6;124(5):557-9. Epub 2008 Nov 6.

Division of Nephrology, Department of Medicine, The University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2785727PMC
December 2008

Mechanism of oxidative DNA damage in diabetes: tuberin inactivation and downregulation of DNA repair enzyme 8-oxo-7,8-dihydro-2'-deoxyguanosine-DNA glycosylase.

Diabetes 2008 Oct 3;57(10):2626-36. Epub 2008 Jul 3.

George O'Brien Kidney Research Center, Department of Medicine, Division of Nephrology, University of Texas Health Science Center, San Antonio, Texas, USA.

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http://dx.doi.org/10.2337/db07-1579DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2551671PMC
October 2008

Resveratrol inhibits PDGF receptor mitogenic signaling in mesangial cells: role of PTP1B.

FASEB J 2008 Oct 20;22(10):3469-82. Epub 2008 Jun 20.

Department of Medicine, University of Texas Health Science Center, San Antonio, Texas 78229-3900, USA.

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http://dx.doi.org/10.1096/fj.08-109488DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2537424PMC
October 2008

Endothelial nitric oxide synthase (eNOS) gene polymorphisms and their association with type 2 diabetes-related traits in Mexican Americans.

Diab Vasc Dis Res 2008 Jun;5(2):109-13

Division of Nephrology, Department of Medicine, The University of Texas Health Science Center, 7703 Floyd Curl Drive, San Antonio, Texas 78229, USA.

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http://dx.doi.org/10.3132/dvdr.2008.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3336872PMC
June 2008

A genome-wide search for linkage to chronic kidney disease in a community-based sample: the SAFHS.

Nephrol Dial Transplant 2008 Oct 28;23(10):3184-91. Epub 2008 Apr 28.

Department of Medicine/Nephrology, University of Texas Health Science Center, South Texas Veterans Health Care System, 7400 Merton Minter Blvd, San Antonio, TX 78229-4404, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720810PMC
October 2008

Relation of low glomerular filtration rate to metabolic disorders in individuals without diabetes and with normoalbuminuria.

Clin J Am Soc Nephrol 2008 May 5;3(3):783-9. Epub 2008 Mar 5.

Department of Medicine, Division of Clinical Epidemiology, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78284-7873, USA.

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http://dx.doi.org/10.2215/CJN.02730707DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386711PMC
May 2008

Tuberin haploinsufficiency is associated with the loss of OGG1 in rat kidney tumors.

Mol Cancer 2008 Jan 24;7:10. Epub 2008 Jan 24.

O'Brien Kidney Research Center, Department of Medicine, University of Texas Health Science Center, San Antonio, TX 78229, USA.

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http://dx.doi.org/10.1186/1476-4598-7-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265742PMC
January 2008

Tuberin regulates the DNA repair enzyme OGG1.

Am J Physiol Renal Physiol 2008 Jan 7;294(1):F281-90. Epub 2007 Nov 7.

George O'Brien Kidney Research Center, Department of Medicine, University of Texas Health Science Center, San Antonio, TX 78229, USA.

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http://dx.doi.org/10.1152/ajprenal.00370.2007DOI Listing
January 2008

Genome scan for determinants of serum uric acid variability.

J Am Soc Nephrol 2007 Dec 31;18(12):3156-63. Epub 2007 Oct 31.

Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.

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December 2007

TGFbeta intercepts nuclear glycogen synthase kinase 3beta to inhibit PDGF-induced DNA synthesis in mesangial cells.

FEBS Lett 2007 Nov 16;581(27):5259-67. Epub 2007 Oct 16.

Department of Medicine, University of Texas Health Science Center, San Antonio, TX 78229-3900, USA.

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November 2007

Mitogenic signaling via platelet-derived growth factor beta in metanephric mesenchymal cells.

J Am Soc Nephrol 2007 Nov 17;18(11):2903-11. Epub 2007 Oct 17.

Division of Nephrology, Department of Medicine, University of Texas Health Science Center, San Antonio, Texas 78229-3900, USA.

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http://www.jasn.org/cgi/doi/10.1681/ASN.2006111229
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November 2007

Genetic polymorphisms in OGG1 and their association with angiomyolipoma, a benign kidney tumor in patients with tuberous sclerosis.

Cancer Biol Ther 2008 Jan 8;7(1):23-7. Epub 2007 Oct 8.

George O' Brien Kidney Research Center, Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229, USA.

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http://dx.doi.org/10.4161/cbt.7.1.5120DOI Listing
January 2008

P2 promoter variants of the hepatocyte nuclear factor 4alpha gene are associated with type 2 diabetes in Mexican Americans.

Diabetes 2007 Feb;56(2):513-7

Department of Medicine/Clinical Epidemiology, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA.

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http://dx.doi.org/10.2337/db06-0881DOI Listing
February 2007

Haplotypes of transcription factor 7-like 2 (TCF7L2) gene and its upstream region are associated with type 2 diabetes and age of onset in Mexican Americans.

Diabetes 2007 Feb;56(2):389-93

Department of Medicine/Clinical Epidemiology, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA.

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http://dx.doi.org/10.2337/db06-0860DOI Listing
February 2007

NAD(P)H oxidases regulate HIF-2alpha protein expression.

J Biol Chem 2007 Mar 2;282(11):8019-26. Epub 2007 Jan 2.

Division of Nephrology, Department of Medicine, George O'Brien Kidney Research Center, University of Texas Health Science Center, San Antonio, Texas 78229-3900, USA.

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http://dx.doi.org/10.1074/jbc.M611569200DOI Listing
March 2007

Arachidonic acid-dependent activation of a p22(phox)-based NAD(P)H oxidase mediates angiotensin II-induced mesangial cell protein synthesis and fibronectin expression via Akt/PKB.

Antioxid Redox Signal 2006 Sep-Oct;8(9-10):1497-508

Department of Medicine, Audie L. Murphy Memorial Hospital Division, The University of Texas Health Science Center, San Antonio, 78229-3900, USA.

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http://www.liebertpub.com/doi/10.1089/ars.2006.8.1497
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January 2007

Kidney involvement in a nongenetic rat model of type 2 diabetes.

Kidney Int 2005 Dec;68(6):2562-71

Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229-3900, USA.

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http://dx.doi.org/10.1111/j.1523-1755.2005.00727.xDOI Listing
December 2005

Genetic basis of diabetic nephropathy.

Am J Ther 2005 Nov-Dec;12(6):555-61

Department of Research, The South Texas Veterans Health Care System, USA.

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http://dx.doi.org/10.1097/01.mjt.0000178770.52610.bfDOI Listing
January 2006

Angiotensin II stimulation of VEGF mRNA translation requires production of reactive oxygen species.

Am J Physiol Renal Physiol 2006 Apr 25;290(4):F927-36. Epub 2005 Oct 25.

Department of Medicine/Nephrology, The University of Texas Health Science Center, South Texas Veterans Health Care System, San Antonio 78229-3900, USA.

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April 2006