Dr. Hani Harb, PhD - Boston Children's Hospital, Harvard Medical School - Division of Immunology

Dr. Hani Harb

PhD

Boston Children's Hospital, Harvard Medical School

Division of Immunology

Boston, MA | United States

Main Specialties: Allergy & Immunology

Additional Specialties: Immunology, Epigenetics, Allergolgy,

ORCID logohttps://orcid.org/0000-0001-8218-2538


Top Author

Dr. Hani Harb, PhD - Boston Children's Hospital, Harvard Medical School - Division of Immunology

Dr. Hani Harb

PhD

Introduction

I am an immunologist. I work as a Research Fellow at Boston Children's Hospital, Harvard Medical School, Boston, USA. My area of research is Asthma, Allergy and epigenetics. I study the role of fine particulate matter from diesel exhaust on airway inflammation trying to find novel biomarkers and deep mechanisms of actions, all in the context of IL-4ra mutations that are predominant in african americans.

furthermore, i study epigenetic mechanisms underlying these changes.

I look always for the next jump in my career both on the scientific as well as the managmental level.

Primary Affiliation: Boston Children's Hospital, Harvard Medical School - Boston, MA , United States

Specialties:

Additional Specialties:

Research Interests:


View Dr. Hani Harb’s Resume / CV

Metrics

Number of Publications

22

Publications

Number of Profile Views

3250

Profile Views

Number of Article Reads

327

Reads

Number of Citations

179

Citations

Education

Mar 2016
Philipps University Marburg
PhD. Immunology and Epigenetics
Jul 2011
Philipps University Marburg
Msc. Infectious Biology
Feb 2006
Amman University
Bsc. Pharmacy

Experience

Apr 2017
Research Fellow
Fellow
Mar 2016
Research Assistant
Researcher
Aug 2011
Junior Research Assistant
Researcher
Aug 2011
Junior Research Assistant
Researcher

Top co-authors

Harald Renz
Harald Renz

Department of Clinical Chemistry and Molecular Diagnostics

15
Holger Garn
Holger Garn

Philipps University of Marburg

6
Daniel P Potaczek
Daniel P Potaczek

Juntendo University School of Medicine

5
Manori Amarasekera
Manori Amarasekera

School of Paediatrics and Child Health

4
Susan L Prescott
Susan L Prescott

University of Western Australia

4
David Martino
David Martino

University of Western Australia

3
Petra I Pfefferle
Petra I Pfefferle

Department of Clinical Chemistry and Molecular Diagnostics

2
Talal A Chatila
Talal A Chatila

Harvard Medical School

2
Erika von Mutius
Erika von Mutius

Medical Research Institute of New Zealand

2

Publications

22Publications

327Reads

179PubMed Central Citations

A Jagged 1-Notch 4 molecular switch mediates airway inflammation induced by ultrafine particles.

J Allergy Clin Immunol 2018 Oct 5;142(4):1243-1256.e17. Epub 2018 Apr 5.

Division of Immunology, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, Mass. Electronic address:

View Article
October 2018
13 Reads
1 Citation
11.480 Impact Factor

Histone modifications and their role in epigenetics of atopy and allergic diseases.

Allergy Asthma Clin Immunol 2018 23;14:39. Epub 2018 May 23.

1Institute of Laboratory Medicine and Pathobiochemistry, Molecular Diagnostics, Philipps University Marburg, Hans-Meerwein-Straße 3, 35043 Marburg, Germany.

View Article
May 2018
3 Reads

Aberrant cognitive phenotypes and altered hippocampal BDNF expression related to epigenetic modifications in mice lacking the post-synaptic scaffolding protein SHANK1: Implications for autism spectrum disorder.

Hippocampus 2017 08 29;27(8):906-919. Epub 2017 May 29.

Behavioral Neuroscience, Experimental and Biological Psychology, Philipps-University of Marburg, Marburg, Germany.

View Article
August 2017
28 Reads
1 Citation
4.160 Impact Factor

Chronic schistosomiasis during pregnancy epigenetically reprograms T-cell differentiation in offspring of infected mothers.

Eur J Immunol 2017 05 11;47(5):841-847. Epub 2017 Apr 11.

Institute of Medical Microbiology, Immunology and Hygiene, Technische Universität München, Munich, Germany.

View Article
May 2017
29 Reads
1 Citation
4.030 Impact Factor

The role of PKCζ in cord blood T-cell maturation towards Th1 cytokine profile and its epigenetic regulation by fish oil.

Biosci Rep 2017 04 27;37(2). Epub 2017 Mar 27.

Department of Immunopathology, SA Pathology, Women and Children's Hospital Campus, School of Medicine; Robinson Research Institute and School of Biological Science, University of Adelaide, Adelaide, South Australia, Australia.

View Article
April 2017
21 Reads
3 Citations
2.640 Impact Factor

Epigenetics and allergy: from basic mechanisms to clinical applications.

Epigenomics 2017 04 21;9(4):539-571. Epub 2017 Mar 21.

Laboratory for Epigenetics & Environment, Centre National de Génotypage, CEA-Institut de Génomique, Evry, France.

View Article
April 2017
37 Reads
6 Citations

The Role of Histone Protein Modifications and Mutations in Histone Modifiers in Pediatric B-Cell Progenitor Acute Lymphoblastic Leukemia.

Cancers (Basel) 2017 Jan 3;9(1). Epub 2017 Jan 3.

Department of Pediatrics, Oncology, Hematology and Diabetology, Medical University of Lodz, Lodz 91-738, Poland.

View Article
January 2017
14 Reads
3 Citations

Recent developments in epigenetics of pediatric asthma.

Curr Opin Pediatr 2016 12;28(6):754-763

aInstitute for Laboratory Medicine and Pathobiochemistry, Molecular Diagnostics, Philipps University Marburg, Marburg, Germany bJohn Paul II Hospital, Krakow, Poland.

View Article
December 2016
8 Reads
5 Citations
2.530 Impact Factor

Draft Genome Sequence and Complete Plasmid Sequence of Acinetobacter lwoffii F78, an Isolate with Strong Allergy-Protective Properties.

Genome Announc 2016 Jul 21;4(4). Epub 2016 Jul 21.

Institute for Medical Microbiology, German Centre for Infection Research (DZIF Partner Site Giessen-Marburg-Langen), Justus-Liebig-University Giessen, Giessen, Germany

View Article
July 2016
10 Reads

Epigenetic Regulation in Early Childhood: A Miniaturized and Validated Method to Assess Histone Acetylation.

Int Arch Allergy Immunol 2015 21;168(3):173-81. Epub 2016 Jan 21.

Institute of Laboratory Medicine, Pathobiochemistry and Molecular Diagnostics, Philipps University Marburg, Marburg, Germany.

View Article
June 2016
17 Reads
5 Citations
2.670 Impact Factor

Childhood allergic asthma is associated with increased IL-13 and FOXP3 histone acetylation.

J Allergy Clin Immunol 2015 Jul 11;136(1):200-2. Epub 2015 Mar 11.

Department of Pulmonary and Allergy, University Children's Hospital Munich, LMU, Munich, Germany; German Center for Lung Research (DZL), Munich, Germany. Electronic address:

View Article
July 2015
8 Reads
5 Citations
11.480 Impact Factor

Transcription factor c-Rel plays a crucial role in driving anti-CD40-mediated innate colitis.

Mucosal Immunol 2015 Mar 6;8(2):307-15. Epub 2014 Aug 6.

1] Institute for Medical Microbiology and Hygiene, Philipps University of Marburg, Marburg, Germany [2] Max Planck Institute for Infection Biology, Department of Immunology, Berlin, Germany.

View Article
March 2015
7 Reads
2 Citations
7.370 Impact Factor

Update on epigenetics in allergic disease.

J Allergy Clin Immunol 2015 Jan;135(1):15-24

Institute for Laboratory Medicine and Pathobiochemistry, Molecular Diagnostics, Philipps-Universität Marburg, Marburg, Germany. Electronic address:

View Article
January 2015
17 Reads
11 Citations
11.480 Impact Factor

Epigenetics in immune development and in allergic and autoimmune diseases.

J Reprod Immunol 2014 Oct 30;104-105:43-8. Epub 2014 Jun 30.

Childhood Allergy and Immunology Research, School of Paediatrics and Child Health, University of Western Australia, Australia; Telethon Kids Institute, Australia.

View Article
October 2014
5 Reads
4 Citations
2.820 Impact Factor

Genome-wide DNA methylation profiling identifies a folate-sensitive region of differential methylation upstream of ZFP57-imprinting regulator in humans.

FASEB J 2014 Sep 2;28(9):4068-76. Epub 2014 Jun 2.

School of Paediatrics and Child Health, University of Western Australia, Perth, Western Australia, Australia;

View Article
September 2014
11 Reads
20 Citations
5.040 Impact Factor

Bioavailability and allergoprotective capacity of milk-associated conjugated linoleic acid in a murine model of allergic airway inflammation.

Int Arch Allergy Immunol 2014 1;163(3):234-42. Epub 2014 Mar 1.

Institute for Laboratory Medicine, Pathobiochemistry and Molecular Diagnostics, Philipps University of Marburg, Marburg, Germany.

View Article
May 2014
12 Reads
1 Citation
2.670 Impact Factor

The transcription factor Interferon Regulatory Factor 4 is required for the generation of protective effector CD8+ T cells.

Proc Natl Acad Sci U S A 2013 Sep 26;110(37):15019-24. Epub 2013 Aug 26.

Institute for Immunology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.

View Article
September 2013
15 Reads
29 Citations
9.810 Impact Factor

Inhibition of HPA-1a alloantibody-mediated platelet destruction by a deglycosylated anti-HPA-1a monoclonal antibody in mice: toward targeted treatment of fetal-alloimmune thrombocytopenia.

Blood 2013 Jul 3;122(3):321-7. Epub 2013 May 3.

Institute for Immunology and Transfusion Medicine, Ernst Moritz Arndt University, Greifswald, Germany.

View Article
July 2013
16 Reads
8 Citations
10.450 Impact Factor

Farm-derived Gram-positive bacterium Staphylococcus sciuri W620 prevents asthma phenotype in HDM- and OVA-exposed mice.

Allergy 2013 Mar 1;68(3):322-9. Epub 2013 Feb 1.

Institute for Laboratory Medicine and Pathobiochemistry, Molecular Diagnostics, Marburg, Germany.

View Article
March 2013
9 Reads
9 Citations
6.030 Impact Factor

Epigenetic regulation in murine offspring as a novel mechanism for transmaternal asthma protection induced by microbes.

J Allergy Clin Immunol 2011 Sep 15;128(3):618-25.e1-7. Epub 2011 Jun 15.

Department of Clinical Chemistry and Molecular Diagnostics, Philipps University of Marburg, Marburg, Germany.

View Article
September 2011
12 Reads
34 Citations
11.480 Impact Factor

Pathogenicity of a disease-associated human IL-4 receptor allele in experimental asthma.

J Exp Med 2009 Sep 21;206(10):2191-204. Epub 2009 Sep 21.

Division of Immunology, Allergy, and Rheumatology, Department of Pediatrics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.

View Article
September 2009
14 Reads
26 Citations
12.520 Impact Factor

Top co-authors

Harald Renz
Harald Renz

Department of Clinical Chemistry and Molecular Diagnostics

15
Holger Garn
Holger Garn

Philipps University of Marburg

6
Daniel P Potaczek
Daniel P Potaczek

Juntendo University School of Medicine

5
Manori Amarasekera
Manori Amarasekera

School of Paediatrics and Child Health

4
Susan L Prescott
Susan L Prescott

University of Western Australia

4
David Martino
David Martino

University of Western Australia

3
Petra I Pfefferle
Petra I Pfefferle

Department of Clinical Chemistry and Molecular Diagnostics

2
Talal A Chatila
Talal A Chatila

Harvard Medical School

2
Erika von Mutius
Erika von Mutius

Medical Research Institute of New Zealand

2