Publications by authors named "Han-Jin Park"

37Publications

Live-cell screening platform using human-induced pluripotent stem cells expressing fluorescence-tagged cytochrome P450 1A1.

FASEB J 2020 Jul 18;34(7):9141-9155. Epub 2020 May 18.

Department of Predictive Toxicology, Korea Institute of Toxicology, Daejeon, Republic of Korea.

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http://dx.doi.org/10.1096/fj.201903110RDOI Listing
July 2020

Synthetic probes for in vitro purification and in vivo tracking of hepatocytes derived from human pluripotent stem cells.

Biomaterials 2019 11 14;222:119431. Epub 2019 Aug 14.

Laboratory of Stem Cells and Tissue Regeneration, Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, 02841, South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2019.119431DOI Listing
November 2019

Generation of cytochrome P450 polymorphic human induced pluripotent stem cell lines with defective CYP activities.

Stem Cell Res 2018 08 25;31:117-121. Epub 2018 Jul 25.

Laboratory of Stem Cells and Tissue Regeneration, Department of Biotechnology, College of Life Sciences and Biotechnology, Science Campus, Korea University, Seoul, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2018.07.010DOI Listing
August 2018

Hepatic esterase activity is increased in hepatocyte-like cells derived from human embryonic stem cells using a 3D culture system.

Biotechnol Lett 2018 May 20;40(5):755-763. Epub 2018 Feb 20.

Predictive Model Research Center, Korea Institute of Toxicology, Daejeon, 34114, Republic of Korea.

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http://dx.doi.org/10.1007/s10529-018-2528-1DOI Listing
May 2018

Human induced pluripotent stem cell line with cytochrome P450 enzyme polymorphism (CYP2C19*2/CYP3A5*3C) generated from lymphoblastoid cells.

Stem Cell Res 2018 03 23;27:34-37. Epub 2017 Dec 23.

Laboratory of Stem Cells and Tissue Regeneration, Department of Biotechnology, College of Life Sciences and Biotechnology, Science Campus, Korea University, Seoul, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2017.12.014DOI Listing
March 2018

Generation of a PXR reporter human induced pluripotent stem cell line (PXR-mCherry hiPSC) using the CRISPR/Cas9 system.

Stem Cell Res 2018 01 6;26:72-75. Epub 2017 Dec 6.

Predictive Model Research Center, Korea Institute of Toxicology, Daejeon 34114, Republic of Korea. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S18735061173025
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http://dx.doi.org/10.1016/j.scr.2017.12.001DOI Listing
January 2018

Phthalazinone Pyrazole Enhances the Hepatic Functions of Human Embryonic Stem Cell-Derived Hepatocyte-Like Cells via Suppression of the Epithelial-Mesenchymal Transition.

Stem Cell Rev Rep 2018 Jun;14(3):438-450

Department of Predictive Toxicology, Korea Institute of Toxicology, Daejeon, 34114, Republic of Korea.

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http://dx.doi.org/10.1007/s12015-017-9795-4DOI Listing
June 2018

Association between sleep disorder and panic disorder in South Korea: Nationwide nested case-control study of data from 2004 to 2013.

Psychiatry Res 2018 02 5;260:286-291. Epub 2017 Dec 5.

Institute of Health Services Research, Yonsei University College of Medicine, Seoul, Republic of Korea; Research and Analysis Team, National Health Insurance Service Ilsan Hospital, Goyang, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.psychres.2017.11.076DOI Listing
February 2018

Lineage-specific Expression of miR-200 Family in Human Embryonic Stem Cells during In Vitro Differentiation.

Int J Stem Cells 2017 May;10(1):28-37

Department of Biological Sciences and Center for Stem Cell Differentiation, KAIST, Daejeon, Korea.

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http://dx.doi.org/10.15283/ijsc17013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488774PMC
May 2017

Prediction of hepatotoxicity for drugs using human pluripotent stem cell-derived hepatocytes.

Cell Biol Toxicol 2018 02 5;34(1):51-64. Epub 2017 Apr 5.

Laboratory of Stem Cells, NEXEL Co., Ltd., 9th floor, 21 Wangsan-ro, Dongdaemun-gu, Seoul, 02580, South Korea.

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http://dx.doi.org/10.1007/s10565-017-9392-yDOI Listing
February 2018

Two zinc-aminoclays' in-vitro cytotoxicity assessment in HeLa cells and in-vivo embryotoxicity assay in zebrafish.

Ecotoxicol Environ Saf 2017 Mar 19;137:103-112. Epub 2016 Dec 19.

Department of BioNano Technology, Gachon University, 1342 Seongnamdaero, Sujeong-gu, Seongnam-si, Gyeonggi-do 13120, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.ecoenv.2016.11.022DOI Listing
March 2017

Xeno-sensing activity of the aryl hydrocarbon receptor in human pluripotent stem cell-derived hepatocyte-like cells.

Sci Rep 2016 Feb 22;6:21684. Epub 2016 Feb 22.

Alternative Toxicological Methods Research Center, Korea Institute of Toxicology, Daejeon 34114, Republic of Korea.

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http://dx.doi.org/10.1038/srep21684DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761945PMC
February 2016

Enhanced Metabolizing Activity of Human ES Cell-Derived Hepatocytes Using a 3D Culture System with Repeated Exposures to Xenobiotics.

Toxicol Sci 2015 Sep 17;147(1):190-206. Epub 2015 Jun 17.

*Laboratory of Stem Cells and Tissue Regeneration, Department of Biotechnology, College of Life Sciences & Biotechnology, Science Campus, Korea University, Seoul, 136-713, Republic of Korea;

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https://academic.oup.com/toxsci/article-lookup/doi/10.1093/t
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http://dx.doi.org/10.1093/toxsci/kfv121DOI Listing
September 2015

Genomic and proteomic analyses of 1,3-dinitrobenzene-induced testicular toxicity in Sprague-Dawley rats.

Reprod Toxicol 2014 Jan 16;43:45-55. Epub 2013 Oct 16.

Korea Institute of Toxicology, Daejeon 305-343, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.reprotox.2013.10.004DOI Listing
January 2014

Effect of temperature gradients on single-strand conformation polymorphism analysis in a capillary electrophoresis system using Pluronic polymer matrix.

Anal Chim Acta 2013 Sep 31;793:114-8. Epub 2013 Jul 31.

School of Interdisciplinary Bioscience and Bioengineering, Pohang University of Science and Technology, Pohang, Gyeongbuk 790-784, Republic of Korea.

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http://dx.doi.org/10.1016/j.aca.2013.07.048DOI Listing
September 2013

Nonylphenol-induced apoptotic cell death in mouse TM4 Sertoli cells via the generation of reactive oxygen species and activation of the ERK signaling pathway.

J Appl Toxicol 2014 Jun 16;34(6):628-36. Epub 2013 May 16.

Division of Toxicological Research, Korea Institute of Toxicology, Daejeon, 305-343, Korea.

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http://dx.doi.org/10.1002/jat.2886DOI Listing
June 2014

Micellar ordered structure effects on high-resolution CE-SSCP using Pluronic triblock copolymer blends.

Electrophoresis 2013 Feb 24;34(4):518-23. Epub 2013 Jan 24.

School of Interdisciplinary Bioscience and Bioengineering, Pohang University of Science and Technology, Pohang, Gyeongbuk, Republic of Korea.

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http://dx.doi.org/10.1002/elps.201200520DOI Listing
February 2013

Gene expression analysis of toxicological pathways in TM3 leydig cell lines treated with Ethane dimethanesulfonate.

J Biochem Mol Toxicol 2012 Jun;26(6):213-23

Division of Research and Development, Korea Institute of Toxicology, Daejeon, 305-343, Republic of Korea.

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http://dx.doi.org/10.1002/jbt.21409DOI Listing
June 2012

miRNA regulation of cytotoxic effects in mouse Sertoli cells exposed to nonylphenol.

Reprod Biol Endocrinol 2011 Sep 14;9:126. Epub 2011 Sep 14.

Division of Research and Development, Korea Institute of Toxicology, 19 Shinsung-ro, Yuseong, Daejeon, 305-343, Korea.

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http://dx.doi.org/10.1186/1477-7827-9-126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196907PMC
September 2011

Inflammatory response in rat lungs with recurrent exposure to welding fumes: a transcriptomic approach.

Toxicol Ind Health 2012 Apr 5;28(3):203-15. Epub 2011 Jul 5.

Division of Research and Development, Korea Institute of Toxicology, Daejeon, Republic of Korea.

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http://dx.doi.org/10.1177/0748233711410906DOI Listing
April 2012

Identification of biomarkers of chemically induced hepatocarcinogenesis in rasH2 mice by toxicogenomic analysis.

Arch Toxicol 2011 Dec 24;85(12):1627-40. Epub 2011 May 24.

Division of Research and Development, Korea Institute of Toxicology, 19 Shinsung-ro, Yuseong-gu, Daejeon 305-343, Korea.

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http://dx.doi.org/10.1007/s00204-011-0715-0DOI Listing
December 2011

Simultaneous gene expression signature of heart and peripheral blood mononuclear cells in astemizole-treated rats.

Arch Toxicol 2010 Aug 11;84(8):609-18. Epub 2010 Mar 11.

Korea Institute of Toxicology, 19 Shinseong-ro, Yuseong-gu, Daejeon 305-343, Republic of Korea.

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http://dx.doi.org/10.1007/s00204-010-0529-5DOI Listing
August 2010

The stoichiometric relationship between KCNH-2 and KCNE-2 in I(Kr) channel formation.

Int J Cardiol 2010 Nov 13;145(2):272-274. Epub 2009 Nov 13.

Korea Institute of Toxicology, 100 Jangdong, Yuseong, Daejeon, 305-343, Republic of Korea; Pharmacology and Toxicology, School of Engineering, University of Science and Technology, 113 Gwahangno, Yuseong, Daejeon, 305-333, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2009.09.552DOI Listing
November 2010

Analysis of Gene Expression in 4,4'-Methylenedianiline-induced Acute Hepatotoxicity.

Toxicol Res 2009 Jun 1;25(2):85-92. Epub 2009 Jun 1.

14Toxicogenomics Team, Korea Institute of Toxicology, 19 Shinsung-ro, Yuseoung, Daejeon, 305-343 Korea.

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http://dx.doi.org/10.5487/TR.2009.25.2.085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006339PMC
June 2009

1,3-Dinitrobenzene induces apoptosis in TM4 mouse Sertoli cells: Involvement of the c-Jun N-terminal kinase (JNK) MAPK pathway.

Toxicol Lett 2009 Sep 27;189(2):145-51. Epub 2009 May 27.

Toxicogenomics Team, Korea Institute of Toxicology, Daejeon 305-343, Republic of Korea.

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http://dx.doi.org/10.1016/j.toxlet.2009.05.014DOI Listing
September 2009

Microarray-based analysis of the lung recovery process after stainless-steel welding fume exposure in Sprague-Dawley rats.

Inhal Toxicol 2009 Feb;21(4):347-73

Division of Research and Development, Korea Institute of Toxicology, Yuseong, Daejeon, Republic of Korea.

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http://dx.doi.org/10.1080/08958370802464281DOI Listing
February 2009

Effects of acetaminophen on hepatic gene expression in mice.

Physiol Chem Phys Med NMR 2006 ;38(2):77-83

Toxicogenomics Team, Korea Institute of Toxicology, 100 Jangdong, Yuseong, Daejeon, 305-343, Republic of Korea.

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June 2008

Studies on the Small Body Size Mouse Developed by Mutagen -Ethyl--nitrosourea.

Toxicol Res 2008 Mar 1;24(1):69-78. Epub 2008 Mar 1.

110Department of Research & Development, Korea Institute of Toxicology, Korea Research Institute of Chemical Technology, P.O BOX 123, Yuseong, Daejeon, 305-343 Korea.

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http://dx.doi.org/10.5487/TR.2008.24.1.069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006338PMC
March 2008

Time Dependent Gene Expression Changes in the Liver of Mice Treated with Benzene.

Biomark Insights 2008 Mar 28;3:191-201. Epub 2008 Mar 28.

Korea Institute of Toxicology, 100-Jang-Dong, Yuseong-Gu, Daejeon-305-600, Korea.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688356PMC
http://dx.doi.org/10.4137/bmi.s590DOI Listing
March 2008

Effects of phalloidin on hepatic gene expression in mice.

Int J Toxicol 2007 May-Jun;26(3):213-20

Toxicogenomics Team, Korea Institute of Toxicology, Yuseong, Daejeon, Republic of Korea.

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http://dx.doi.org/10.1080/10915810701352697DOI Listing
December 2007