Publications by authors named "Hal Berman"

30Publications

Author Correction: Human somatic cell mutagenesis creates genetically tractable sarcomas.

Authors:
Sam D Molyneux Paul D Waterhouse Dawne Shelton Yang W Shao Christopher M Watling Qing-Lian Tang Isaac S Harris Brendan C Dickson Pirashaanthy Tharmapalan Geir K Sandve Xiaoyang Zhang Swneke D Bailey Hal Berman Jay S Wunder Zsuzsanna Izsvák Mathieu Lupien Tak W Mak Rama Khokha

Nat Genet 2020 Apr;52(4):464

Department of Medical Biophysics, Ontario Cancer Institute, University of Toronto, Toronto, Ontario, Canada.

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April 2020

Tumor cell expression of B7-H4 correlates with higher frequencies of tumor-infiltrating APCs and higher CXCL17 expression in human epithelial ovarian cancer.

Authors:
Heather L MacGregor Carlos Garcia-Batres Azin Sayad Andrew Elia Hal K Berman Aras Toker Sarah Rachel Katz Patricia A Shaw Blaise A Clarke Sarah Q Crome Celine Robert-Tissot Marcus Q Bernardini Linh T Nguyen Pamela S Ohashi

Oncoimmunology 2019;8(12):e1665460. Epub 2019 Sep 30.

Department of Immunology, University of Toronto, Toronto, Ontario, Canada.

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September 2019

Mammary stem cells and progenitors: targeting the roots of breast cancer for prevention.

Authors:
Pirashaanthy Tharmapalan Mathepan Mahendralingam Hal K Berman Rama Khokha

EMBO J 2019 07 21;38(14):e100852. Epub 2019 Jun 21.

Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, ON, Canada.

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July 2019

Breast specimen handling and reporting in the post-neoadjuvant setting: challenges and advances.

Authors:
Miralem Mrkonjic Hal K Berman Susan J Done Bruce Youngson Anna Marie Mulligan

J Clin Pathol 2019 Feb;72(2):120-132

Laboratory Medicine Program, University Health Network, Toronto, Ontario, Canada

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February 2019

Mammary molecular portraits reveal lineage-specific features and progenitor cell vulnerabilities.

Authors:
Alison E Casey Ankit Sinha Rajat Singhania Julie Livingstone Paul Waterhouse Pirashaanthy Tharmapalan Jennifer Cruickshank Mona Shehata Erik Drysdale Hui Fang Hyeyeon Kim Ruth Isserlin Swneke Bailey Tiago Medina Genevieve Deblois Yu-Jia Shiah Dalia Barsyte-Lovejoy Stefan Hofer Gary Bader Mathieu Lupien Cheryl Arrowsmith Stefan Knapp Daniel De Carvalho Hal Berman Paul C Boutros Thomas Kislinger Rama Khokha

J Cell Biol 2018 08 19;217(8):2951-2974. Epub 2018 Jun 19.

Princess Margaret Cancer Centre, Toronto, ON, Canada

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August 2018

The origins of breast cancer associated with mammographic density: a testable biological hypothesis.

Authors:
Norman Boyd Hal Berman Jie Zhu Lisa J Martin Martin J Yaffe Sofia Chavez Greg Stanisz Greg Hislop Anna M Chiarelli Salomon Minkin Andrew D Paterson

Breast Cancer Res 2018 03 7;20(1):17. Epub 2018 Mar 7.

Genetics and Genome Biology, Hospital for Sick Children Research Institute, Toronto, ON, Canada.

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March 2018

Impact of multi-gene mutational profiling on clinical trial outcomes in metastatic breast cancer.

Authors:
Rossanna C Pezo Tom W Chen Hal K Berman Anna M Mulligan Albiruni A Razak Lillian L Siu David W Cescon Eitan Amir Christine Elser David G Warr Srikala S Sridhar Celeste Yu Lisa Wang Tracy L Stockley Suzanne Kamel-Reid Philippe L Bedard

Breast Cancer Res Treat 2018 Feb 24;168(1):159-168. Epub 2017 Nov 24.

Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, 7-723 700 University Avenue, Toronto, Canada.

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February 2018

Neurobiological Mechanisms of Chemotherapy-induced Cognitive Impairment in a Transgenic Model of Breast Cancer.

Authors:
Gordon Winocur Hal Berman Mary Nguyen Malcolm A Binns Mark Henkelman Matthijs van Eede Micheline Piquette-Miller Melanie J Sekeres J Martin Wojtowicz Johnson Yu Haibo Zhang Ian F Tannock

Neuroscience 2018 01 4;369:51-65. Epub 2017 Nov 4.

Divisions of Medical Oncology and Hematology, Princess Margaret Cancer Center, Toronto, Canada.

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January 2018

Notch Shapes the Innate Immunophenotype in Breast Cancer.

Authors:
Qiang Shen Brenda Cohen Weiyue Zheng Ramtin Rahbar Bernard Martin Kiichi Murakami Sara Lamorte Patrycja Thompson Hal Berman Juan Carlos Zúñiga-Pflücker Pamela S Ohashi Michael Reedijk

Cancer Discov 2017 11 8;7(11):1320-1335. Epub 2017 Aug 8.

Campbell Family Institute for Cancer Research, Ontario Cancer Institute, Toronto, Ontario, Canada.

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November 2017

A distinct innate lymphoid cell population regulates tumor-associated T cells.

Authors:
Sarah Q Crome Linh T Nguyen Sandra Lopez-Verges S Y Cindy Yang Bernard Martin Jennifer Y Yam Dylan J Johnson Jessica Nie Michael Pniak Pei Hua Yen Anca Milea Ramlogan Sowamber Sarah Rachel Katz Marcus Q Bernardini Blaise A Clarke Patricia A Shaw Philipp A Lang Hal K Berman Trevor J Pugh Lewis L Lanier Pamela S Ohashi

Nat Med 2017 Mar 6;23(3):368-375. Epub 2017 Feb 6.

Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.

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March 2017

Molecular profiling of advanced solid tumors and patient outcomes with genotype-matched clinical trials: the Princess Margaret IMPACT/COMPACT trial.

Authors:
Tracy L Stockley Amit M Oza Hal K Berman Natasha B Leighl Jennifer J Knox Frances A Shepherd Eric X Chen Monika K Krzyzanowska Neesha Dhani Anthony M Joshua Ming-Sound Tsao Stefano Serra Blaise Clarke Michael H Roehrl Tong Zhang Mahadeo A Sukhai Nadia Califaretti Mateya Trinkaus Patricia Shaw Theodorus van der Kwast Lisa Wang Carl Virtanen Raymond H Kim Albiruni R A Razak Aaron R Hansen Celeste Yu Trevor J Pugh Suzanne Kamel-Reid Lillian L Siu Philippe L Bedard

Genome Med 2016 10 25;8(1):109. Epub 2016 Oct 25.

Cancer Genomics Program, Princess Margaret Cancer Centre, Toronto, Canada.

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October 2016

RANKL/RANK control Brca1 mutation- .

Authors:
Verena Sigl Kwadwo Owusu-Boaitey Purna A Joshi Anoop Kavirayani Gerald Wirnsberger Maria Novatchkova Ivona Kozieradzki Daniel Schramek Nnamdi Edokobi Jerome Hersl Aishia Sampson Ashley Odai-Afotey Conxi Lazaro Eva Gonzalez-Suarez Miguel A Pujana For Cimba Holger Heyn Enrique Vidal Jennifer Cruickshank Hal Berman Renu Sarao Melita Ticevic Iris Uribesalgo Luigi Tortola Shuan Rao Yen Tan Georg Pfeiler Eva Yhp Lee Zsuzsanna Bago-Horvath Lukas Kenner Helmuth Popper Christian Singer Rama Khokha Laundette P Jones Josef M Penninger

Cell Res 2016 07 31;26(7):761-74. Epub 2016 May 31.

IMBA, Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Vienna 1030, Austria.

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July 2016

Expansion of stem cells counteracts age-related mammary regression in compound Timp1/Timp3 null mice.

Authors:
Hartland W Jackson Paul Waterhouse Ankit Sinha Thomas Kislinger Hal K Berman Rama Khokha

Nat Cell Biol 2015 Mar 23;17(3):217-27. Epub 2015 Feb 23.

1] Department of Medical Biophysics, University of Toronto, Toronto, Ontario M5G 2M9, Canada [2] Princess Margaret Cancer Centre/University Health Network, Toronto, Ontario M5G 2M9, Canada [3] Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario M5S 1A8, Canada.

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March 2015

Glutathione and thioredoxin antioxidant pathways synergize to drive cancer initiation and progression.

Authors:
Isaac S Harris Aislinn E Treloar Satoshi Inoue Masato Sasaki Chiara Gorrini Kim Chung Lee Ka Yi Yung Dirk Brenner Christiane B Knobbe-Thomsen Maureen A Cox Andrew Elia Thorsten Berger David W Cescon Adewunmi Adeoye Anne Brüstle Sam D Molyneux Jacqueline M Mason Wanda Y Li Kazuo Yamamoto Andrew Wakeham Hal K Berman Rama Khokha Susan J Done Terrance J Kavanagh Ching-Wan Lam Tak W Mak

Cancer Cell 2015 Feb 22;27(2):211-22. Epub 2015 Jan 22.

The Campbell Family Institute for Breast Cancer Research, University Health Network, 620 University Avenue, Toronto, ON M5G 2M9, Canada; Department of Medical Biophysics, University Health Network, 620 University Avenue, Toronto, ON M5G 2M9, Canada. Electronic address:

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February 2015

B7-H4 expression by nonhematopoietic cells in the tumor microenvironment promotes antitumor immunity.

Authors:
Ramtin Rahbar Albert Lin Magar Ghazarian Helen-Loo Yau Sangeetha Paramathas Philipp A Lang Anita Schildknecht Alisha R Elford Carlos Garcia-Batres Bernard Martin Hal K Berman Wey L Leong David R McCready Michael Reedijk Susan J Done Naomi Miller Bruce Youngson Woong-Kyung Suh Tak W Mak Pamela S Ohashi

Cancer Immunol Res 2015 Feb 19;3(2):184-95. Epub 2014 Dec 19.

Campbell Family Institute for Breast Cancer Research, Princess Margaret Cancer Centre, Toronto, Ontario, Canada. Department of Immunology, University of Toronto, Toronto, Ontario, Canada. Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.

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February 2015

Human somatic cell mutagenesis creates genetically tractable sarcomas.

Authors:
Sam D Molyneux Paul D Waterhouse Dawne Shelton Yang W Shao Christopher M Watling Qing-Lian Tang Isaac S Harris Brendan C Dickson Pirashaanthy Tharmapalan Geir K Sandve Xiaoyang Zhang Swneke D Bailey Hal Berman Jay S Wunder Zsuzsanna Izsvák Zsuzsanna Iszvak Mathieu Lupien Tak W Mak Rama Khokha

Nat Genet 2014 Sep 17;46(9):964-72. Epub 2014 Aug 17.

Department of Medical Biophysics, Ontario Cancer Institute, University of Toronto, Toronto, Ontario, Canada.

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September 2014

Mislocalization of the cell polarity protein scribble promotes mammary tumorigenesis and is associated with basal breast cancer.

Authors:
Michael E Feigin S Dipikaa Akshinthala Kiyomi Araki Avi Z Rosenberg Lakshmi B Muthuswamy Bernard Martin Brian D Lehmann Hal K Berman Jennifer A Pietenpol Robert D Cardiff Senthil K Muthuswamy

Cancer Res 2014 Jun 24;74(11):3180-94. Epub 2014 Mar 24.

Authors' Affiliations: Cold Spring Harbor Laboratory, Cold Spring Harbor, New York; Princess Margaret Cancer Center, Campbell Family Institute for Breast Cancer Research, Department of Medical Biophysics, University of Toronto; Ontario Institute for Cancer Research, Ontario, Canada; Center for Comparative Medicine, University of California, Davis, Davis, California; and Department of Biochemistry, Vanderbilt University, Nashville, TennesseeAuthors' Affiliations: Cold Spring Harbor Laboratory, Cold Spring Harbor, New York; Princess Margaret Cancer Center, Campbell Family Institute for Breast Cancer Research, Department of Medical Biophysics, University of Toronto; Ontario Institute for Cancer Research, Ontario, Canada; Center for Comparative Medicine, University of California, Davis, Davis, California; and Department of Biochemistry, Vanderbilt University, Nashville, Tennessee

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June 2014

Retinoblastoma pathway deregulatory mechanisms determine clinical outcome in high-grade serous ovarian carcinoma.

Authors:
Anca Milea Sophia H L George Donco Matevski Haiyan Jiang Mary Madunic Hal K Berman Mona L Gauthier Brenda Gallie Patricia A Shaw

Mod Pathol 2014 Jul 13;27(7):991-1001. Epub 2013 Dec 13.

1] Campbell Family Institute for Breast Cancer Research, Toronto, ON, Canada [2] Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada [3] Princess Margaret Cancer Centre, Toronto, ON, Canada [4] Department of Pathology, University Health Network, Toronto, ON, Canada.

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July 2014

BRCA1 interacts with Nrf2 to regulate antioxidant signaling and cell survival.

Authors:
Chiara Gorrini Pegah S Baniasadi Isaac S Harris Jennifer Silvester Satoshi Inoue Bryan Snow Purna A Joshi Andrew Wakeham Sam D Molyneux Bernard Martin Peter Bouwman David W Cescon Andrew J Elia Zoe Winterton-Perks Jennifer Cruickshank Dirk Brenner Alan Tseng Melinda Musgrave Hal K Berman Rama Khokha Jos Jonkers Tak W Mak Mona L Gauthier

J Exp Med 2013 Jul 15;210(8):1529-44. Epub 2013 Jul 15.

The Campbell Family Institute for Breast Cancer Research, University Health Network, Toronto, Ontario M5G 2M9, Canada.

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July 2013

High throughput kinase inhibitor screens reveal TRB3 and MAPK-ERK/TGFβ pathways as fundamental Notch regulators in breast cancer.

Authors:
Julia Izrailit Hal K Berman Alessandro Datti Jeffrey L Wrana Michael Reedijk

Proc Natl Acad Sci U S A 2013 Jan 14;110(5):1714-9. Epub 2013 Jan 14.

Campbell Family Institute for Breast Cancer Research, Ontario Cancer Institute, Toronto, ON, Canada M5G 2M9.

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January 2013

CD36 repression activates a multicellular stromal program shared by high mammographic density and tumor tissues.

Authors:
Rosa Anna DeFilippis Hang Chang Nancy Dumont Joseph T Rabban Yunn-Yi Chen Gerald V Fontenay Hal K Berman Mona L Gauthier Jianxin Zhao Donglei Hu James J Marx Judy A Tjoe Elad Ziv Maria Febbraio Karla Kerlikowske Bahram Parvin Thea D Tlsty

Cancer Discov 2012 Sep 9;2(9):826-39. Epub 2012 Jul 9.

Department of Pathology, Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA 94143, USA.

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September 2012

Spatial organization and correlations of cell nuclei in brain tumors.

Authors:
Yang Jiao Hal Berman Tim-Rasmus Kiehl Salvatore Torquato

PLoS One 2011 16;6(11):e27323. Epub 2011 Nov 16.

Physical Science in Oncology Center, Princeton Institute for the Science and Technology of Materials, Princeton University, Princeton, New Jersey, United States of America.

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March 2012

p16(INK4a) expression and breast cancer risk in women with atypical hyperplasia.

Authors:
Derek C Radisky Marta Santisteban Hal K Berman Mona L Gauthier Marlene H Frost Carol A Reynolds Robert A Vierkant V Shane Pankratz Daniel W Visscher Thea D Tlsty Lynn C Hartmann

Cancer Prev Res (Phila) 2011 Dec 15;4(12):1953-60. Epub 2011 Sep 15.

Division of Biochemistry/Molecular Biology, Mayo Clinic in Jacksonville, Jacksonville, Florida 32224, USA.

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December 2011

Plasminogen activator uPA is a direct transcriptional target of the JAG1-Notch receptor signaling pathway in breast cancer.

Authors:
Mamiko Shimizu Brenda Cohen Pavel Goldvasser Hal Berman Carl Virtanen Michael Reedijk

Cancer Res 2011 Jan;71(1):277-86

Campbell Family Institute for Breast Cancer Research, Ontario Cancer Institute, Toronto, Ontario, Canada.

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January 2011

Biomarker expression and risk of subsequent tumors after initial ductal carcinoma in situ diagnosis.

Authors:
Karla Kerlikowske Annette M Molinaro Mona L Gauthier Hal K Berman Fred Waldman James Bennington Henry Sanchez Cynthia Jimenez Kim Stewart Karen Chew Britt-Marie Ljung Thea D Tlsty

J Natl Cancer Inst 2010 May 28;102(9):627-37. Epub 2010 Apr 28.

University of California, San Francisco, CA 94121, USA. [corrected]

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May 2010

Premalignant breast neoplasia: a paradigm of interlesional and intralesional molecular heterogeneity and its biological and clinical ramifications.

Authors:
Hal K Berman Mona L Gauthier Thea D Tlsty

Cancer Prev Res (Phila) 2010 May 27;3(5):579-87. Epub 2010 Apr 27.

Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.

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May 2010

DNA damage drives an activin a-dependent induction of cyclooxygenase-2 in premalignant cells and lesions.

Authors:
Colleen Fordyce Tim Fessenden Curtis Pickering Jason Jung Veena Singla Hal Berman Thea Tlsty

Cancer Prev Res (Phila) 2010 Feb 22;3(2):190-201. Epub 2009 Dec 22.

Department of Pathology, University of California, San Francisco, 94143, USA.

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February 2010

Abrogated response to cellular stress identifies DCIS associated with subsequent tumor events and defines basal-like breast tumors.

Authors:
Mona L Gauthier Hal K Berman Caroline Miller Krystyna Kozakeiwicz Karen Chew Dan Moore Joseph Rabban Yunn Yi Chen Karla Kerlikowske Thea D Tlsty

Cancer Cell 2007 Nov;12(5):479-91

Department of Pathology, University of California, San Francisco, CA 94143, USA.

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November 2007

Stratification of breast cancer risk in women with atypia: a Mayo cohort study.

Authors:
Amy C Degnim Daniel W Visscher Hal K Berman Marlene H Frost Thomas A Sellers Robert A Vierkant Shaun D Maloney V Shane Pankratz Piet C de Groen Wilma L Lingle Karthik Ghosh Lois Penheiter Thea Tlsty L Joseph Melton Carol A Reynolds Lynn C Hartmann

J Clin Oncol 2007 Jul 11;25(19):2671-7. Epub 2007 Jun 11.

Division of General Surgery, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.

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July 2007

p38 regulates cyclooxygenase-2 in human mammary epithelial cells and is activated in premalignant tissue.

Authors:
Mona L Gauthier Curtis R Pickering Caroline J Miller Colleen A Fordyce Karen L Chew Hal K Berman Thea D Tlsty

Cancer Res 2005 Mar;65(5):1792-9

Department of Pathology, University of California San Francisco Comprehensive Cancer Center, University of California at San Francisco, San Francisco, California 94143-0511, USA.

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March 2005