Håkan Melhus

Håkan Melhus

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Håkan Melhus

Publications by authors named "Håkan Melhus"

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Physical activity is associated with a large number of cardiovascular-specific proteins: Cross-sectional analyses in two independent cohorts.

Eur J Prev Cardiol 2019 Aug 14:2047487319868033. Epub 2019 Aug 14.

1 Department of Surgical Sciences, Orthopaedics, Uppsala University, Sweden.

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http://dx.doi.org/10.1177/2047487319868033DOI Listing
August 2019

A Genome-Wide Association Study of Bisphosphonate-Associated Atypical Femoral Fracture.

Calcif Tissue Int 2019 Jul 20;105(1):51-67. Epub 2019 Apr 20.

Department of Medical Sciences, Uppsala University, Uppsala, Sweden.

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http://link.springer.com/10.1007/s00223-019-00546-9
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http://dx.doi.org/10.1007/s00223-019-00546-9DOI Listing
July 2019

Serum Parathyroid Hormone and Risk of Coronary Artery Disease: Exploring Causality using Mendelian Randomization.

J Clin Endocrinol Metab 2019 Jul 16. Epub 2019 Jul 16.

Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1210/jc.2019-01063DOI Listing
July 2019

Developmental low-dose exposure to bisphenol A induces chronic inflammation, bone marrow fibrosis and reduces bone stiffness in female rat offspring only.

Environ Res 2019 Jul 11;177:108584. Epub 2019 Jul 11.

Department of Medical Sciences, Occupational and Environmental Medicine, Uppsala University, Uppsala, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.envres.2019.108584DOI Listing
July 2019

Seasonal variability of NT-proBNP in Swedish primary care patients.

Chronobiol Int 2017 14;34(10):1473-1477. Epub 2017 Sep 14.

a Department of Medical Sciences , Uppsala University Hospital, Uppsala University , Uppsala , Sweden.

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http://dx.doi.org/10.1080/07420528.2017.1366500DOI Listing
February 2019

Disentangling the genetics of lean mass.

Authors:
David Karasik M Carola Zillikens Yi-Hsiang Hsu Ali Aghdassi Kristina Akesson Najaf Amin Inês Barroso David A Bennett Lars Bertram Murielle Bochud Ingrid B Borecki Linda Broer Aron S Buchman Liisa Byberg Harry Campbell Natalia Campos-Obando Jane A Cauley Peggy M Cawthon John C Chambers Zhao Chen Nam H Cho Hyung Jin Choi Wen-Chi Chou Steven R Cummings Lisette C P G M de Groot Phillip L De Jager Ilja Demuth Luda Diatchenko Michael J Econs Gudny Eiriksdottir Anke W Enneman Joel Eriksson Johan G Eriksson Karol Estrada Daniel S Evans Mary F Feitosa Mao Fu Christian Gieger Harald Grallert Vilmundur Gudnason Launer J Lenore Caroline Hayward Albert Hofman Georg Homuth Kim M Huffman Lise B Husted Thomas Illig Erik Ingelsson Till Ittermann John-Olov Jansson Toby Johnson Reiner Biffar Joanne M Jordan Antti Jula Magnus Karlsson Kay-Tee Khaw Tuomas O Kilpeläinen Norman Klopp Jacqueline S L Kloth Daniel L Koller Jaspal S Kooner William E Kraus Stephen Kritchevsky Zoltán Kutalik Teemu Kuulasmaa Johanna Kuusisto Markku Laakso Jari Lahti Thomas Lang Bente L Langdahl Markus M Lerch Joshua R Lewis Christina Lill Lars Lind Cecilia Lindgren Yongmei Liu Gregory Livshits Östen Ljunggren Ruth J F Loos Mattias Lorentzon Jian'an Luan Robert N Luben Ida Malkin Fiona E McGuigan Carolina Medina-Gomez Thomas Meitinger Håkan Melhus Dan Mellström Karl Michaëlsson Braxton D Mitchell Andrew P Morris Leif Mosekilde Maria Nethander Anne B Newman Jeffery R O'Connell Ben A Oostra Eric S Orwoll Aarno Palotie Munro Peacock Markus Perola Annette Peters Richard L Prince Bruce M Psaty Katri Räikkönen Stuart H Ralston Samuli Ripatti Fernando Rivadeneira John A Robbins Jerome I Rotter Igor Rudan Veikko Salomaa Suzanne Satterfield Sabine Schipf Chan Soo Shin Albert V Smith Shad B Smith Nicole Soranzo Timothy D Spector Alena Stancáková Kari Stefansson Elisabeth Steinhagen-Thiessen Lisette Stolk Elizabeth A Streeten Unnur Styrkarsdottir Karin M A Swart Patricia Thompson Cynthia A Thomson Gudmar Thorleifsson Unnur Thorsteinsdottir Emmi Tikkanen Gregory J Tranah André G Uitterlinden Cornelia M van Duijn Natasja M van Schoor Liesbeth Vandenput Peter Vollenweider Henry Völzke Jean Wactawski-Wende Mark Walker Nicholas J Wareham Dawn Waterworth Michael N Weedon H-Erich Wichmann Elisabeth Widen Frances M K Williams James F Wilson Nicole C Wright Laura M Yerges-Armstrong Lei Yu Weihua Zhang Jing Hua Zhao Yanhua Zhou Carrie M Nielson Tamara B Harris Serkalem Demissie Douglas P Kiel Claes Ohlsson

Am J Clin Nutr 2019 Feb;109(2):276-287

Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1093/ajcn/nqy272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500901PMC
February 2019

Bones in human CYP26B1 deficiency and rats with hypervitaminosis A phenocopy overexpression.

Bone Rep 2018 Dec 21;9:27-36. Epub 2018 Jun 21.

Division of Pathology, Department of Laboratory Medicine, Karolinska Institutet, Karolinska University Hospital, SE-14152 Huddinge, Sweden.

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http://dx.doi.org/10.1016/j.bonr.2018.06.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039751PMC
December 2018

Serum 25-Hydroxyvitamin D Concentrations and Major Depression: A Mendelian Randomization Study.

Nutrients 2018 Dec 15;10(12). Epub 2018 Dec 15.

Department of Surgical Sciences, Uppsala University, SE-751 85 Uppsala, Sweden.

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http://dx.doi.org/10.3390/nu10121987DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316636PMC
December 2018

Type 2 Diabetes in Relation to Hip Bone Density, Area, and Bone Turnover in Swedish Men and Women: A Cross-Sectional Study.

Calcif Tissue Int 2018 11 26;103(5):501-511. Epub 2018 Jun 26.

Department of Surgical Sciences, Orthopaedics, Uppsala University, Epihubben, Uppsala Science Park, 751 85, Uppsala, Sweden.

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http://dx.doi.org/10.1007/s00223-018-0446-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182615PMC
November 2018

A Trial of Blood-Pressure Reduction in Black Barbershops.

N Engl J Med 2018 07;379(2):199

Uppsala University Hospital, Uppsala, Sweden

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http://dx.doi.org/10.1056/NEJMc1806026DOI Listing
July 2018

Studies of indirect and direct effects of hypervitaminosis A on rat bone by comparing free access to food and pair-feeding.

Ups J Med Sci 2018 Jun 26;123(2):82-85. Epub 2018 Apr 26.

a Department of Medical Sciences , Section of Clinical Pharmacology, Uppsala University , Uppsala , Sweden.

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http://dx.doi.org/10.1080/03009734.2018.1448020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055747PMC
June 2018

Circulating Serum 25-Hydroxyvitamin D Levels and Bone Mineral Density: Mendelian Randomization Study.

J Bone Miner Res 2018 05 9;33(5):840-844. Epub 2018 Feb 9.

Unit of Orthopedics, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1002/jbmr.3389DOI Listing
May 2018

Intake of Milk or Fermented Milk Combined With Fruit and Vegetable Consumption in Relation to Hip Fracture Rates: A Cohort Study of Swedish Women.

J Bone Miner Res 2018 03 27;33(3):449-457. Epub 2017 Nov 27.

Department of Surgical Sciences, Section of Orthopedics, Uppsala University, Uppsala University Hospital, Uppsala, Sweden.

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http://dx.doi.org/10.1002/jbmr.3324DOI Listing
March 2018

Questionnaire-Based Anti-Inflammatory Diet Index as a Predictor of Low-Grade Systemic Inflammation.

Antioxid Redox Signal 2018 Jan 12;28(1):78-84. Epub 2017 Oct 12.

1 Unit of Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet , Stockholm, Sweden .

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http://dx.doi.org/10.1089/ars.2017.7330DOI Listing
January 2018

Low-dose developmental exposure to bisphenol A induces sex-specific effects in bone of Fischer 344 rat offspring.

Environ Res 2017 11 1;159:61-68. Epub 2017 Aug 1.

Department of Medical Sciences, Occupational and Environmental Medicine, Uppsala, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.envres.2017.07.020DOI Listing
November 2017

Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.

Authors:
M Carola Zillikens Serkalem Demissie Yi-Hsiang Hsu Laura M Yerges-Armstrong Wen-Chi Chou Lisette Stolk Gregory Livshits Linda Broer Toby Johnson Daniel L Koller Zoltán Kutalik Jian'an Luan Ida Malkin Janina S Ried Albert V Smith Gudmar Thorleifsson Liesbeth Vandenput Jing Hua Zhao Weihua Zhang Ali Aghdassi Kristina Åkesson Najaf Amin Leslie J Baier Inês Barroso David A Bennett Lars Bertram Rainer Biffar Murielle Bochud Michael Boehnke Ingrid B Borecki Aron S Buchman Liisa Byberg Harry Campbell Natalia Campos Obanda Jane A Cauley Peggy M Cawthon Henna Cederberg Zhao Chen Nam H Cho Hyung Jin Choi Melina Claussnitzer Francis Collins Steven R Cummings Philip L De Jager Ilja Demuth Rosalie A M Dhonukshe-Rutten Luda Diatchenko Gudny Eiriksdottir Anke W Enneman Mike Erdos Johan G Eriksson Joel Eriksson Karol Estrada Daniel S Evans Mary F Feitosa Mao Fu Melissa Garcia Christian Gieger Thomas Girke Nicole L Glazer Harald Grallert Jagvir Grewal Bok-Ghee Han Robert L Hanson Caroline Hayward Albert Hofman Eric P Hoffman Georg Homuth Wen-Chi Hsueh Monica J Hubal Alan Hubbard Kim M Huffman Lise B Husted Thomas Illig Erik Ingelsson Till Ittermann John-Olov Jansson Joanne M Jordan Antti Jula Magnus Karlsson Kay-Tee Khaw Tuomas O Kilpeläinen Norman Klopp Jacqueline S L Kloth Heikki A Koistinen William E Kraus Stephen Kritchevsky Teemu Kuulasmaa Johanna Kuusisto Markku Laakso Jari Lahti Thomas Lang Bente L Langdahl Lenore J Launer Jong-Young Lee Markus M Lerch Joshua R Lewis Lars Lind Cecilia Lindgren Yongmei Liu Tian Liu Youfang Liu Östen Ljunggren Mattias Lorentzon Robert N Luben William Maixner Fiona E McGuigan Carolina Medina-Gomez Thomas Meitinger Håkan Melhus Dan Mellström Simon Melov Karl Michaëlsson Braxton D Mitchell Andrew P Morris Leif Mosekilde Anne Newman Carrie M Nielson Jeffrey R O'Connell Ben A Oostra Eric S Orwoll Aarno Palotie Stephen C J Parker Munro Peacock Markus Perola Annette Peters Ozren Polasek Richard L Prince Katri Räikkönen Stuart H Ralston Samuli Ripatti John A Robbins Jerome I Rotter Igor Rudan Veikko Salomaa Suzanne Satterfield Eric E Schadt Sabine Schipf Laura Scott Joban Sehmi Jian Shen Chan Soo Shin Gunnar Sigurdsson Shad Smith Nicole Soranzo Alena Stančáková Elisabeth Steinhagen-Thiessen Elizabeth A Streeten Unnur Styrkarsdottir Karin M A Swart Sian-Tsung Tan Mark A Tarnopolsky Patricia Thompson Cynthia A Thomson Unnur Thorsteinsdottir Emmi Tikkanen Gregory J Tranah Jaakko Tuomilehto Natasja M van Schoor Arjun Verma Peter Vollenweider Henry Völzke Jean Wactawski-Wende Mark Walker Michael N Weedon Ryan Welch H-Erich Wichmann Elisabeth Widen Frances M K Williams James F Wilson Nicole C Wright Weijia Xie Lei Yu Yanhua Zhou John C Chambers Angela Döring Cornelia M van Duijn Michael J Econs Vilmundur Gudnason Jaspal S Kooner Bruce M Psaty Timothy D Spector Kari Stefansson Fernando Rivadeneira André G Uitterlinden Nicholas J Wareham Vicky Ossowski Dawn Waterworth Ruth J F Loos David Karasik Tamara B Harris Claes Ohlsson Douglas P Kiel

Nat Commun 2017 11 7;8(1):1414. Epub 2017 Nov 7.

Hebrew SeniorLife, Institute for Aging Research, Roslindale, MA, 02131, USA.

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http://dx.doi.org/10.1038/s41467-017-01008-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676783PMC
November 2017

Medication Reviews Bridging Healthcare (MedBridge): Study protocol for a pragmatic cluster-randomised crossover trial.

Contemp Clin Trials 2017 10 21;61:126-132. Epub 2017 Jul 21.

Pharmacy Department, Uppsala University Hospital, Ing.13 2 tr, 751 85 Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.cct.2017.07.019DOI Listing
October 2017

Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis.

Am J Hum Genet 2017 Aug 27;101(2):227-238. Epub 2017 Jul 27.

Department of Human Genetics, McGill University, Montreal, QC H3A 1B1, Canada; Lady Davis Institute for Medical Research, Jewish General Hospital, McGill University, Montreal, QC H3T 1E2, Canada; Department of Twin Research and Genetic Epidemiology, King's College London, London WC2R 2LS, UK; Department of Medicine, McGill University, Montreal, QC H3G 1Y6, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2017.06.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544392PMC
August 2017

Reply to Y Mao and H Yu.

Am J Clin Nutr 2017 08;106(2):698-699

From the Departments of Surgical Sciences, Orthopedics (LB, e-mail: Public Health and Caring Sciences, Clinical Nutrition and Metabolism (EO, BK, TC, and PS) and Geriatrics (LK); and Medical Sciences, Clinical Pharmacogenomics and Osteoporosis (HM), Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.3945/ajcn.117.156752DOI Listing
August 2017

Reply to WB Grant.

Am J Clin Nutr 2017 08;106(2):700-701

From the Departments of Surgical Sciences, Orthopedics (LB, e-mail: Public Health and Caring Sciences, Clinical Nutrition and Metabolism (EO, BK, TC, and PS); Medical Sciences, Clinical Pharmacogenomics and Osteoporosis (HM); and Public Health and Caring Sciences, Geriatrics, (LK) Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.3945/ajcn.117.160168DOI Listing
August 2017

Long-term a posteriori dietary patterns and risk of hip fractures in a cohort of women.

Eur J Epidemiol 2017 07 5;32(7):605-616. Epub 2017 Jun 5.

Department of Surgical Sciences, Section of Orthopedics, Uppsala University, Dag Hammarskjölds väg 14B, UCR/MTC, Uppsala Science Park, 751 83, Uppsala, Sweden.

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http://dx.doi.org/10.1007/s10654-017-0267-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570766PMC
July 2017

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.

Authors:
M Carola Zillikens Serkalem Demissie Yi-Hsiang Hsu Laura M Yerges-Armstrong Wen-Chi Chou Lisette Stolk Gregory Livshits Linda Broer Toby Johnson Daniel L Koller Zoltán Kutalik Jian'an Luan Ida Malkin Janina S Ried Albert V Smith Gudmar Thorleifsson Liesbeth Vandenput Jing Hua Zhao Weihua Zhang Ali Aghdassi Kristina Åkesson Najaf Amin Leslie J Baier Inês Barroso David A Bennett Lars Bertram Rainer Biffar Murielle Bochud Michael Boehnke Ingrid B Borecki Aron S Buchman Liisa Byberg Harry Campbell Natalia Campos Obanda Jane A Cauley Peggy M Cawthon Henna Cederberg Zhao Chen Nam H Cho Hyung Jin Choi Melina Claussnitzer Francis Collins Steven R Cummings Philip L De Jager Ilja Demuth Rosalie A M Dhonukshe-Rutten Luda Diatchenko Gudny Eiriksdottir Anke W Enneman Mike Erdos Johan G Eriksson Joel Eriksson Karol Estrada Daniel S Evans Mary F Feitosa Mao Fu Melissa Garcia Christian Gieger Thomas Girke Nicole L Glazer Harald Grallert Jagvir Grewal Bok-Ghee Han Robert L Hanson Caroline Hayward Albert Hofman Eric P Hoffman Georg Homuth Wen-Chi Hsueh Monica J Hubal Alan Hubbard Kim M Huffman Lise B Husted Thomas Illig Erik Ingelsson Till Ittermann John-Olov Jansson Joanne M Jordan Antti Jula Magnus Karlsson Kay-Tee Khaw Tuomas O Kilpeläinen Norman Klopp Jacqueline S L Kloth Heikki A Koistinen William E Kraus Stephen Kritchevsky Teemu Kuulasmaa Johanna Kuusisto Markku Laakso Jari Lahti Thomas Lang Bente L Langdahl Lenore J Launer Jong-Young Lee Markus M Lerch Joshua R Lewis Lars Lind Cecilia Lindgren Yongmei Liu Tian Liu Youfang Liu Östen Ljunggren Mattias Lorentzon Robert N Luben William Maixner Fiona E McGuigan Carolina Medina-Gomez Thomas Meitinger Håkan Melhus Dan Mellström Simon Melov Karl Michaëlsson Braxton D Mitchell Andrew P Morris Leif Mosekilde Anne Newman Carrie M Nielson Jeffrey R O'Connell Ben A Oostra Eric S Orwoll Aarno Palotie Stephen C J Parker Munro Peacock Markus Perola Annette Peters Ozren Polasek Richard L Prince Katri Räikkönen Stuart H Ralston Samuli Ripatti John A Robbins Jerome I Rotter Igor Rudan Veikko Salomaa Suzanne Satterfield Eric E Schadt Sabine Schipf Laura Scott Joban Sehmi Jian Shen Chan Soo Shin Gunnar Sigurdsson Shad Smith Nicole Soranzo Alena Stančáková Elisabeth Steinhagen-Thiessen Elizabeth A Streeten Unnur Styrkarsdottir Karin M A Swart Sian-Tsung Tan Mark A Tarnopolsky Patricia Thompson Cynthia A Thomson Unnur Thorsteinsdottir Emmi Tikkanen Gregory J Tranah Jaakko Tuomilehto Natasja M van Schoor Arjun Verma Peter Vollenweider Henry Völzke Jean Wactawski-Wende Mark Walker Michael N Weedon Ryan Welch H-Erich Wichmann Elisabeth Widen Frances M K Williams James F Wilson Nicole C Wright Weijia Xie Lei Yu Yanhua Zhou John C Chambers Angela Döring Cornelia M van Duijn Michael J Econs Vilmundur Gudnason Jaspal S Kooner Bruce M Psaty Timothy D Spector Kari Stefansson Fernando Rivadeneira André G Uitterlinden Nicholas J Wareham Vicky Ossowski Dawn Waterworth Ruth J F Loos David Karasik Tamara B Harris Claes Ohlsson Douglas P Kiel

Nat Commun 2017 07 19;8(1):80. Epub 2017 Jul 19.

Hebrew SeniorLife, Institute for Aging Research, Roslindale, MA, 02131, USA.

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http://dx.doi.org/10.1038/s41467-017-00031-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517526PMC
July 2017

Vitamin D is not associated with incident dementia or cognitive impairment: an 18-y follow-up study in community-living old men.

Am J Clin Nutr 2017 04 15;105(4):936-943. Epub 2017 Feb 15.

Public Health and Caring Sciences/Geriatrics, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.3945/ajcn.116.141531DOI Listing
April 2017

The Impact of Disease and Drugs on Hip Fracture Risk.

Calcif Tissue Int 2017 01 26;100(1):1-12. Epub 2016 Sep 26.

Department of Surgical Sciences, Orthopedics, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1007/s00223-016-0194-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214955PMC
January 2017

[Vitamin D supplementation may do more harm than good. Evidence-based threshold values for vitamin D status are still lacking].

Lakartidningen 2015 Jun 2;112. Epub 2015 Jun 2.

- , Sweden - , Sweden.

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June 2015

The fall descriptions and health characteristics of older adults with hip fracture: a mixed methods study.

BMC Geriatr 2015 Apr 8;15:40. Epub 2015 Apr 8.

Department of Public Health and Caring Sciences, Geriatrics, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1186/s12877-015-0036-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428087PMC
April 2015

Parathyroid hormone and calcium are independently associated with subclinical vascular disease in a community-based cohort.

Atherosclerosis 2015 Feb 20;238(2):420-6. Epub 2014 Dec 20.

Department of Medical Sciences, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.atherosclerosis.2014.12.027DOI Listing
February 2015

A tool for prediction of risk of rehospitalisation and mortality in the hospitalised elderly: secondary analysis of clinical trial data.

BMJ Open 2015 Feb 18;5(2):e007259. Epub 2015 Feb 18.

Department of Medical Sciences, Uppsala University, Uppsala, Sweden Uppsala Clinical Research Center, Uppsala, Sweden.

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http://dx.doi.org/10.1136/bmjopen-2014-007259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336459PMC
February 2015

Plasma parathyroid hormone is associated with vascular dementia and cerebral hyperintensities in two community-based cohorts.

J Clin Endocrinol Metab 2014 Nov 20;99(11):4181-9. Epub 2014 Aug 20.

Uppsala Clinical Research Center (E.H., J.Ä.), Departments of Public Health and Caring Sciences/Geriatrics (L.K.), Radiology (R.N., E.-M.L., H.A., L.J.), Surgical Sciences (K.M.), and Medical Sciences (E.H., H.M., L.L., J.Ä.), Uppsala University, 75185 Uppsala, Sweden; and the School of Health and Social Studies (J.Ä.), Dalarna University, 79131 Falun, Sweden.

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http://dx.doi.org/10.1210/jc.2014-1736DOI Listing
November 2014

Milk intake and risk of mortality and fractures in women and men: cohort studies.

BMJ 2014 Oct 28;349:g6015. Epub 2014 Oct 28.

Department of Surgical Sciences, Uppsala University, SE-751 85 Uppsala, Sweden.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212225PMC
http://dx.doi.org/10.1136/bmj.g6015DOI Listing
October 2014

Vitamin a is a negative regulator of osteoblast mineralization.

PLoS One 2013 10;8(12):e82388. Epub 2013 Dec 10.

Department of Medical Sciences, Section of Clinical Pharmacology, Uppsala University, Uppsala, Sweden.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0082388PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858291PMC
September 2014

Vitamin D and endothelial vasodilation in older individuals: data from the PIVUS study.

J Clin Endocrinol Metab 2014 Sep 3;99(9):3382-9. Epub 2014 Jun 3.

Geriatric Rehabilitation Department (M.M., F.D.V., F.L., G.P.C.), University Hospital of Parma, 43126 Parma, Italy; Department of Clinical and Experimental Medicine (M.M., G.P.C.), Section of Geriatrics, University of Parma, 43126 Parma, Italy; Department of Internal Medicine (E.V.), Division of Geriatrics, and Sealy Center on Aging, University of Texas Medical Branch, Galveston, Galveston, Texas 77555-0264; Department of Clinical Medicine, Cardiovascular and Immunological Sciences (F.G.), University of Naples Federico II, 80138 Napoli, Italy; Cardiac Surgery Unit (G.D.C.), Community Hospital of Brescia, 25123 Brescia, Italy; Azienda USL Piacenza (C.C.), 23121 Piacenza, Italy; Department of Medical Sciences (H.M.), Uppsala University, 751 85 Uppsala, Sweden; Department of Surgical Sciences (K.M.), Uppsala University, 751 85 Uppsala, Sweden; Department of Medicine (T.C.), Uppsala University Hospital, 751 85 Uppsala, Sweden; and Department of Public Health and Caring Sciences (L.L.), Section of Clinical Nutrition and Metabolism, Uppsala University, 751 85 Uppsala, Sweden.

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http://dx.doi.org/10.1210/jc.2014-1536DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154089PMC
September 2014

Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study.

Authors:
Karani S Vimaleswaran Alana Cavadino Diane J Berry Rolf Jorde Aida Karina Dieffenbach Chen Lu Alexessander Couto Alves Hiddo J Lambers Heerspink Emmi Tikkanen Joel Eriksson Andrew Wong Massimo Mangino Kathleen A Jablonski Ilja M Nolte Denise K Houston Tarunveer Singh Ahluwalia Peter J van der Most Dorota Pasko Lina Zgaga Elisabeth Thiering Veronique Vitart Ross M Fraser Jennifer E Huffman Rudolf A de Boer Ben Schöttker Kai-Uwe Saum Mark I McCarthy Josée Dupuis Karl-Heinz Herzig Sylvain Sebert Anneli Pouta Jaana Laitinen Marcus E Kleber Gerjan Navis Mattias Lorentzon Karen Jameson Nigel Arden Jackie A Cooper Jayshree Acharya Rebecca Hardy Olli Raitakari Samuli Ripatti Liana K Billings Jari Lahti Clive Osmond Brenda W Penninx Lars Rejnmark Kurt K Lohman Lavinia Paternoster Ronald P Stolk Dena G Hernandez Liisa Byberg Emil Hagström Håkan Melhus Erik Ingelsson Dan Mellström Osten Ljunggren Ioanna Tzoulaki Stela McLachlan Evropi Theodoratou Carla M T Tiesler Antti Jula Pau Navarro Alan F Wright Ozren Polasek James F Wilson Igor Rudan Veikko Salomaa Joachim Heinrich Harry Campbell Jacqueline F Price Magnus Karlsson Lars Lind Karl Michaëlsson Stefania Bandinelli Timothy M Frayling Catharina A Hartman Thorkild I A Sørensen Stephen B Kritchevsky Bente Lomholt Langdahl Johan G Eriksson Jose C Florez Tim D Spector Terho Lehtimäki Diana Kuh Steve E Humphries Cyrus Cooper Claes Ohlsson Winfried März Martin H de Borst Meena Kumari Mika Kivimaki Thomas J Wang Chris Power Hermann Brenner Guri Grimnes Pim van der Harst Harold Snieder Aroon D Hingorani Stefan Pilz John C Whittaker Marjo-Riitta Järvelin Elina Hyppönen

Lancet Diabetes Endocrinol 2014 Sep 25;2(9):719-29. Epub 2014 Jun 25.

Population, Policy and Practice, UCL Institute of Child Health, London, UK; School of Population Health, Sansom Institute for Health Research, University of South Australia, Adelaide, SA, Australia; South Australian Health and Medical Research Institute, Adelaide, SA, Australia. Electronic address:

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http://dx.doi.org/10.1016/S2213-8587(14)70113-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582411PMC
September 2014

Plasma-parathyroid hormone is associated with subclinical and clinical atherosclerotic disease in 2 community-based cohorts.

Arterioscler Thromb Vasc Biol 2014 Jul 13;34(7):1567-73. Epub 2014 Mar 13.

From the Uppsala Clinical Research Center (E.H., E.I., J.S., J.Ä.), Departments of Radiology (T.H., H.A., L.J.) and Medical Sciences (E.H., J.Ä., E.I., J.S., L.L.), Uppsala University, Uppsala, Sweden; and the School of Health and Social Studies, Dalarna University, Falun, Sweden (J.Ä.).

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http://dx.doi.org/10.1161/ATVBAHA.113.303062DOI Listing
July 2014

Long-term dietary vitamin D intake and risk of fracture and osteoporosis: a longitudinal cohort study of Swedish middle-aged and elderly women.

J Clin Endocrinol Metab 2014 Mar 11;99(3):781-90. Epub 2013 Dec 11.

Department of Surgical Sciences (G.S., L.B., E.W.L., K.M., H.Ma.), Section of Orthopedics; Department of Medical Sciences (H.Me.), Section of Clinical Pharmacology; and Department of Surgical Sciences (R.G.), Section of Anesthesiology and Intensive Care, Uppsala University, SE-751 85 Uppsala, Sweden; and Department of Nutritional Epidemiology (A.W.), Institute of Environmental Medicine, Karolinska Institutet, SE-171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1210/jc.2013-1738DOI Listing
March 2014

Impact of hip fracture on mortality: a cohort study in hip fracture discordant identical twins.

J Bone Miner Res 2014 Feb;29(2):424-31

Department of Surgical Sciences, Section of Orthopaedics, Uppsala University, Uppsala, Sweden; Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1002/jbmr.2029DOI Listing
February 2014

Intake and serum concentrations of α-tocopherol in relation to fractures in elderly women and men: 2 cohort studies.

Am J Clin Nutr 2014 Jan 13;99(1):107-14. Epub 2013 Nov 13.

Department of Surgical Sciences, Orthopedics, Uppsala University, Uppsala, Sweden (KM and LB); the Division of Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden (AW); the School of Health and Social Studies, Dalarna University, Falun, Sweden (JÄ); the Department of Public Health and Caring Sciences, Geriatrics, Uppsala University, Uppsala, Sweden (JÄ); and the Department of Medical Sciences, Clinical Pharmacology, Uppsala University, Uppsala, Sweden (HM).

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http://dx.doi.org/10.3945/ajcn.113.064691DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3862449PMC
January 2014

Genetic influence on bone phenotypes and body composition: a Swedish twin study.

J Bone Miner Metab 2013 Nov 7;31(6):681-9. Epub 2013 Apr 7.

Section of Orthopedics, Department of Surgical Sciences, Uppsala University, S75185, Uppsala, Sweden,

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http://dx.doi.org/10.1007/s00774-013-0455-8DOI Listing
November 2013

Association of spironolactone use with all-cause mortality in heart failure: a propensity scored cohort study.

Circ Heart Fail 2013 Mar 5;6(2):174-83. Epub 2013 Feb 5.

Department of Medicine, Karolinska Institutet, Stockholm, Sweden. mail

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March 2013

Prescription and transcription errors in multidose-dispensed medications on discharge from hospital: an observational and interventional study.

J Eval Clin Pract 2013 Feb 29;19(1):185-91. Epub 2011 Dec 29.

Apoteket Farmaci AB, Hospital Pharmacy, Uppsala University Hospital, Uppsala, Sweden.

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http://dx.doi.org/10.1111/j.1365-2753.2011.01798.xDOI Listing
February 2013

Long term calcium intake and rates of all cause and cardiovascular mortality: community based prospective longitudinal cohort study.

BMJ 2013 Feb 12;346:f228. Epub 2013 Feb 12.

Department of Surgical Sciences, Section of Orthopedics, Uppsala University, SE-751 85 Uppsala, Sweden.

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http://dx.doi.org/10.1136/bmj.f228DOI Listing
February 2013

Adamts1 is highly induced in rachitic bones of FGF23 transgenic mice and participates in degradation of non-mineralized bone matrix collagen.

Biochem Biophys Res Commun 2013 Jan 19;430(3):901-6. Epub 2012 Dec 19.

Department of Medical Sciences, Uppsala University, SE-75185 Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.bbrc.2012.12.056DOI Listing
January 2013

Prehospital Trauma Life Support (PHTLS) training of ambulance caregivers and impact on survival of trauma victims.

Resuscitation 2012 Oct 23;83(10):1259-64. Epub 2012 Feb 23.

Department of Surgical Sciences, Anaesthesiology and Intensive Care, Uppsala University, Uppsala, Sweden.

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October 2012

Relations of circulating vitamin D concentrations with left ventricular geometry and function.

Eur J Heart Fail 2012 Sep 21;14(9):985-91. Epub 2012 Jun 21.

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, SE-171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1093/eurjhf/hfs091DOI Listing
September 2012

Heritable and environmental factors in the causation of clinical vertebral fractures.

Calcif Tissue Int 2012 Jun 18;90(6):458-64. Epub 2012 Apr 18.

Section of Orthopedics, Department of Surgical Sciences, Uppsala University, 75185, Uppsala, Sweden.

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http://dx.doi.org/10.1007/s00223-012-9592-7DOI Listing
June 2012

[Vitamin D and health: Lack of evidence is the biggest problem].

Lakartidningen 2012 Mar 21-27;109(12):604-5

Institutionen för medicinska vetenskaper, Uppsala universitet.

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June 2012

Over-expression of Adamts1 in mice alters bone mineral density.

J Bone Miner Metab 2012 May 15;30(3):304-11. Epub 2011 Oct 15.

Department of Medical Sciences, Section of Clinical Pharmacology, University Hospital, Ing 70 3tr Foa2 Lab22, 75185, Uppsala, Sweden.

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http://dx.doi.org/10.1007/s00774-011-0322-4DOI Listing
May 2012

Prediction of fracture risk in men: a cohort study.

J Bone Miner Res 2012 Apr;27(4):797-807

Department of Surgical Sciences, Orthopedics, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1002/jbmr.1498DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415621PMC
April 2012

Seasonal variations of insulin sensitivity from a euglycemic insulin clamp in elderly men.

Ups J Med Sci 2012 Mar 9;117(1):35-40. Epub 2011 Nov 9.

Department of Public Health/Geriatrics, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.3109/03009734.2011.628422DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282240PMC
March 2012

Microarray profiling of diaphyseal bone of rats suffering from hypervitaminosis A.

Calcif Tissue Int 2012 Mar 4;90(3):219-29. Epub 2012 Jan 4.

Department of Medical Sciences, Section of Clinical Pharmacology, Uppsala University, UAS, Ing 70 3tr Foa2 Lab22, 75185 Uppsala, Sweden.

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http://link.springer.com/10.1007/s00223-011-9561-6
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March 2012

Prehospital injury deaths--strengthening the case for prevention: nationwide cohort study.

J Trauma Acute Care Surg 2012 Mar;72(3):765-72

Department of Surgical Sciences-Anesthesiology and Intensive Care, Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1097/TA.0b013e3182288272DOI Listing
March 2012

Dietary calcium intake and risk of fracture and osteoporosis: prospective longitudinal cohort study.

BMJ 2011 May 24;342:d1473. Epub 2011 May 24.

Department of Surgical Sciences, Section of Orthopaedics, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1136/bmj.d1473DOI Listing
May 2011

Extent and consequences of misclassified injury diagnoses in a national hospital discharge registry.

Inj Prev 2011 Apr 26;17(2):108-13. Epub 2010 Nov 26.

Department of Surgical Sciences, Anesthesiology and Intensive Care, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1136/ip.2010.028951DOI Listing
April 2011

High dietary intake of retinol leads to bone marrow hypoxia and diaphyseal endosteal mineralization in rats.

Bone 2011 Mar 28;48(3):496-506. Epub 2010 Oct 28.

Department of Medical Sciences, Section of Clinical Pharmacology, University Hospital, Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.bone.2010.10.169DOI Listing
March 2011

Plasma parathyroid hormone and risk of congestive heart failure in the community.

Eur J Heart Fail 2010 Nov 26;12(11):1186-92. Epub 2010 Aug 26.

Uppsala Clinical Research Center, Uppsala University, 751 85 Uppsala, Sweden.

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http://dx.doi.org/10.1093/eurjhf/hfq134DOI Listing
November 2010

Population density and mortality among individuals in motor vehicle crashes.

Inj Prev 2010 Oct 30;16(5):302-8. Epub 2010 Jun 30.

Department of Surgical Sciences, Anaesthesiology and Intensive Care, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1136/ip.2009.024414DOI Listing
October 2010

Plasma vitamin D and mortality in older men: a community-based prospective cohort study.

Am J Clin Nutr 2010 Oct 18;92(4):841-8. Epub 2010 Aug 18.

Department of Surgical Sciences and Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.3945/ajcn.2010.29749DOI Listing
October 2010

Determining vitamin D status: a comparison between commercially available assays.

PLoS One 2010 Jul 13;5(7):e11555. Epub 2010 Jul 13.

Section of Orthopaedics, Department of Surgical Sciences, Uppsala University, [corrected] Uppsala, Sweden.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903481PMC
July 2010

Plasma 25-hydroxyvitamin D levels and fracture risk in a community-based cohort of elderly men in Sweden.

J Clin Endocrinol Metab 2010 Jun 23;95(6):2637-45. Epub 2010 Mar 23.

Department of Medical Sciences, Uppsala University, SE-75185 Uppsala, Sweden.

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http://dx.doi.org/10.1210/jc.2009-2699DOI Listing
June 2010

Liraglutide for weight loss in obese people.

Lancet 2010 Feb;375(9714):551; author reply 552-3

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February 2010

Coffee consumption and CYP1A2 genotype in relation to bone mineral density of the proximal femur in elderly men and women: a cohort study.

Nutr Metab (Lond) 2010 Feb 22;7:12. Epub 2010 Feb 22.

Research and Development Department, Toxicology Division, National Food Administration, Box 622, SE-751 26 Uppsala, Sweden.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842270PMC
February 2010

Serum intact FGF23 associate with left ventricular mass, hypertrophy and geometry in an elderly population.

Atherosclerosis 2009 Dec 21;207(2):546-51. Epub 2009 May 21.

Department of Medical Sciences, Uppsala University Hospital, Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.atherosclerosis.2009.05.013DOI Listing
December 2009

Seasonal genetic influence on serum 25-hydroxyvitamin D levels: a twin study.

PLoS One 2009 Nov 13;4(11):e7747. Epub 2009 Nov 13.

Department of Surgical Sciences, Section of Orthopaedics, Uppsala University, Uppsala, Sweden.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2774516PMC
November 2009

Cardiovascular diseases and risk of hip fracture.

JAMA 2009 Oct;302(15):1666-73

Department of Surgical Sciences, Section of Orthopaedics, Uppsala University, SE-751 85 Uppsala, Sweden.

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http://dx.doi.org/10.1001/jama.2009.1463DOI Listing
October 2009

Total mortality after changes in leisure time physical activity in 50 year old men: 35 year follow-up of population based cohort.

Br J Sports Med 2009 Jul;43(7):482

Department of Surgical Sciences, Section of Orthopaedics, and Uppsala Clinical Research Centre, Uppsala University, SE-75185 Uppsala, Sweden.

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July 2009

A comprehensive pharmacist intervention to reduce morbidity in patients 80 years or older: a randomized controlled trial.

Arch Intern Med 2009 May;169(9):894-900

Division of Pharmacokinetics and Drug Therapy, Department of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1001/archinternmed.2009.71DOI Listing
May 2009

Total mortality after changes in leisure time physical activity in 50 year old men: 35 year follow-up of population based cohort.

BMJ 2009 Mar 5;338:b688. Epub 2009 Mar 5.

Department of Surgical Sciences, Section of Orthopaedics, and Uppsala Clinical Research Centre, Uppsala University, SE-75185 Uppsala, Sweden.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654773PMC
http://dx.doi.org/10.1136/bmj.b688DOI Listing
March 2009

Simply ask them about their balance--future fracture risk in a nationwide cohort study of twins.

Am J Epidemiol 2009 Jan 8;169(2):143-9. Epub 2008 Dec 8.

Department of Surgical Sciences, Section of Orthopaedics, University Hospital, Uppsala, Sweden.

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http://dx.doi.org/10.1093/aje/kwn379DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2727259PMC
January 2009

Type I collagen alpha1 Sp1 polymorphism and the risk of cruciate ligament ruptures or shoulder dislocations.

Am J Sports Med 2008 Dec 31;36(12):2432-6. Epub 2008 Jul 31.

Department of Surgical Sciences, Section of Orthopedics, University Hospital, Uppsala, Sweden.

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http://journals.sagepub.com/doi/10.1177/0363546508320805
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December 2008

Serum adiponectin in elderly men does not correlate with fracture risk.

J Clin Endocrinol Metab 2008 Oct 22;93(10):4041-7. Epub 2008 Jul 22.

Department of Medical Sciences, University Hospital, Uppsala, Sweden.

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https://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.
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http://dx.doi.org/10.1210/jc.2008-0617DOI Listing
October 2008

Digoxin and mortality in atrial fibrillation: a prospective cohort study.

Eur J Clin Pharmacol 2007 Oct 8;63(10):959-71. Epub 2007 Aug 8.

Department of Medical Sciences, Clinical Pharmacology, Uppsala University Hospital, Uppsala University, 751 85, Uppsala, Sweden.

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http://link.springer.com/10.1007/s00228-007-0346-9
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October 2007

Associations between androgen and Vitamin D receptor microsatellites and postmenopausal breast cancer.

Cancer Epidemiol Biomarkers Prev 2007 Sep;16(9):1775-83

Department of Etiological Research, The Cancer Registry of Norway, 0310 Oslo, Norway.

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http://dx.doi.org/10.1158/1055-9965.EPI-06-1096DOI Listing
September 2007

Leisure physical activity and the risk of fracture in men.

PLoS Med 2007 Jun;4(6):e199

Section of Orthopaedics, Department of Surgical Sciences, University Hospital, Uppsala, Sweden.

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http://dx.doi.org/10.1371/journal.pmed.0040199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1892039PMC
June 2007

The positive effect of dietary vitamin D intake on bone mineral density in men is modulated by the polyadenosine repeat polymorphism of the vitamin D receptor.

Bone 2006 Dec 24;39(6):1343-51. Epub 2006 Jul 24.

Department of Surgical Sciences, Section of Orthopaedics, University Hospital, S-751 85 Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.bone.2006.06.003DOI Listing
December 2006

Digitalis intoxication induced by paroxetine co-administration.

Lancet 2006 Dec;368(9551):1963

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December 2006

Using genotyping to predict responses to anti-hypertensive treatment.

Trends Pharmacol Sci 2005 Sep;26(9):443-7

Department of Medical Sciences, Uppsala University Hospital, 751 85 Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.tips.2005.07.008DOI Listing
September 2005

Genetic liability to fractures in the elderly.

Arch Intern Med 2005 Sep;165(16):1825-30

Department of Surgical Sciences, Uppsala University Hospital, Uppsala, Sweden.

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http://dx.doi.org/10.1001/archinte.165.16.1825DOI Listing
September 2005

Smoking and the risk of fracture in older men.

J Bone Miner Res 2005 Jul 14;20(7):1208-15. Epub 2005 Feb 14.

Section of Orthopedics, Department of Surgical Sciences, University Hospital, Uppsala, Sweden.

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http://dx.doi.org/10.1359/JBMR.050208DOI Listing
July 2005