Hakan Cangul

Hakan Cangul

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Hakan Cangul

Hakan Cangul

Publications by authors named "Hakan Cangul"

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31Publications

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Digenic DUOX1 and DUOX2 Mutations in Cases With Congenital Hypothyroidism.

J Clin Endocrinol Metab 2017 09;102(9):3085-3090

University of Cambridge Metabolic Research Laboratories, Wellcome Trust-Medical Research Council Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge CB2 0QQ, United Kingdom.

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http://dx.doi.org/10.1210/jc.2017-00529DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587079PMC
September 2017

Comprehensive Screening of Eight Known Causative Genes in Congenital Hypothyroidism With Gland-in-Situ.

J Clin Endocrinol Metab 2016 12 15;101(12):4521-4531. Epub 2016 Aug 15.

University of Cambridge Metabolic Research Laboratories (A.K.N., E.S., G.L., V.K.K.C., N.S.), Wellcome Trust-Medical Research Council Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, United Kingdom; Department of Human Genetics (E.G.S., C.A.A.), The Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom; Research Centre for Regenerative and Restorative Medicine (H.C.), Department of Medical Genetics Istanbul Medipol University, Kavacık, Istanbul, Turkey; Pediatric Endocrine Unit (S.A., I.U.), Department of Child Health, Sultan Qaboos University Hospital, Muscat, Oman; Paediatric Endocrinology Department (A.D.), Mafraq Hospital, AbuDhabi, United Arab Emirates; Pediatric Department Prince Mohamed Bin Abdulaziz Hospital (A.M.H.), Madinah, Kingdom of Saudi Arabia; Department of Paediatrics (M.A.), Madina Maternity & Children's Hospital Madina Munawara, Saudi Arabia; 8. Department of Endocrinology (C.P.), Great Ormond St Hospital for Children, London, United Kingdom; Department of Paediatrics (N.N.), Luton and Dunstable University Hospital, Luton, United Kingdom; Division of Paediatric Endocrinology (Z.A.), Dr Sami Ulus Woman Health and Children Research Hospital Ankara, Turkey; Department of Paediatric Endocrinology (H.S.), Uludağ University, School of Medicine Bursa, Turkey; Department of Paediatric Endocrinology (E.B.), Dokuz Eylül University, Faculty of Medicine Izmir, Turkey; Developmental Endocrinology Research Group (M.D.), Section of Genetics and Epigenetics in Health and Disease, Genetics and Genomic Medicine Programme, University College London Institute of Child Health, London, United Kingdom; Department of Paediatrics (S.S.), Leicester Royal infirmary, Leicester United Kingdom; Centre for Paediatrics and Child Health (P.G.M.), Institute of Human Development University of Manchester, and Royal Manchester Children's Hospital, Manchester, United Kingdom; Paediatric Endocrinology Division (A.B.), College of Medicine, King Saud University and King Saud University Medical City, Riyadh, Saudi Arabia; Department of Paediatrics (R.W., A.T.), University of Cambridge, Cambridge Biomedical Campus, Cambridge, United Kingdom; W Midlands Regional Genetics Laboratory (R.I.), Birmingham Women's Hospital NHS Foundation Trust, Birmingham, United Kingdom; Department of Paediatric Endocrinology (R.P.), Central Manchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom; Department of Paediatrics (K.T.), Diana Princess of Wales Hospital, Grimsby, United Kingdom; Department of Paediatric Endocrinology (J.H.D.), University Hospital Southampton, Southampton, United Kingdom; Department of Paediatrics (V.P.), Peterborough and Stamford Hospitals NHS Foundation Trust, Peterborough, United Kingdom; Department of Clinical Genetics (S.-M.P.), Cambridge University Hospitals NHS Foundation Trust, Cambridge United Kingdom; London N W Healthcare NHS Trust (A.F.M.), Harrow, Middlesex, United Kingdom; Division of Population Medicine (J.W.G.), School of Medicine, Cardiff University, Heath Park Cardiff, UK; Department of Paediatric Endocrinology (A.A.), St George's University Hospitals NHS Foundation Trust, London, United Kingdom; Centre for Endocrinology (E.P.-G.), William Harvey Research Institute, Queen Mary University London and Children's Hospital, Barts Health NHS Trust, London, United Kingdom; Department of Medical Genetics (H.M., K.B., E.R.M.), University of Cambridge and NIHR Cambridge Biomedical Research Centre, Cambridge, United Kingdom.

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http://dx.doi.org/10.1210/jc.2016-1879DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155683PMC
December 2016

A truncating TPO mutation (Y55X) in patients with hypothyroidism and total iodide organification defect.

Endocr Res 2015 20;40(3):146-50. Epub 2014 Oct 20.

Department of Medical Genetics, Bahcesehir University School of Medicine , Istanbul , Turkey .

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http://dx.doi.org/10.3109/07435800.2014.967354DOI Listing
April 2016

A Homozygous Nonsense Thyroid Peroxidase Mutation (R540X) Consistently Causes Congenital Hypothyroidism in Two Siblings Born to a Consanguineous Family.

J Clin Res Pediatr Endocrinol 2015 Dec;7(4):323-8

Medipol University International Faculty of Medicine, Department of Medical Genetics, İstanbul, Turkey Phone: +90 216 681 51 00 E-mail:

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http://dx.doi.org/10.4274/jcrpe.1920DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805212PMC
December 2015

A Homozygous TPO Gene Duplication (c.1184_1187dup4) Causes Congenital Hypothyroidism in Three Siblings Born to a Consanguineous Family.

J Pediatr Genet 2015 Dec 14;4(4):194-8. Epub 2015 Oct 14.

Pediatric Endocrinology Unit, Istanbul Faculty of Medicine, Istanbul University, Turkey.

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https://www.thieme-connect.com/products/ejournals/pdf/10.105
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http://dx.doi.org/10.1055/s-0035-1565268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906531PMC
December 2015

The Missense Alteration A5T of the Thyroid Peroxidase Gene is Pathogenic and Associated with Mild Congenital Hypothyroidism.

J Clin Res Pediatr Endocrinol 2015 Sep;7(3):238-41

Medipol University Faculty of Medicine, Department of Medical Genetics, İstanbul, Turkey Phone: +90 216 681 51 00 E-mail:

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http://dx.doi.org/10.4274/jcrpe.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4677561PMC
September 2015

Nanoparticle growth and surface chemistry changes in cell-conditioned culture medium.

Philos Trans R Soc Lond B Biol Sci 2015 Feb;370(1661):20140100

Centre for Rare Diseases and Personalised Medicine, School of Clinical and Experimental Medicine, University of Birmingham, Birmingham B15 2TT, UK.

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http://rstb.royalsocietypublishing.org/cgi/doi/10.1098/rstb.
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http://dx.doi.org/10.1098/rstb.2014.0100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275914PMC
February 2015

One Base Deletion (c.2422delT) in the TPO Gene Causes Severe Congenital Hypothyroidism.

J Clin Res Pediatr Endocrinol 2014 Sep;6(3):169-73

Bahçeşehir University Faculty of Medicine, Department of Medical Genetics, İstanbul, Turkey. E-ma-il:

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http://dx.doi.org/10.4274/Jcrpe.1404DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293646PMC
September 2014

Jervell and Lange-Nielsen syndrome: homozygous missense mutation of KCNQ1 in a Turkish family.

Pediatr Cardiol 2013 12;34(8):2063-7. Epub 2013 Feb 12.

Department of Paediatric Cardiology, Faculty of Medicine, University of Uludag, Bursa, Turkey.

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http://dx.doi.org/10.1007/s00246-013-0634-3DOI Listing
July 2014

Novel truncating thyroglobulin gene mutations associated with congenital hypothyroidism.

Endocrine 2014 Mar 15;45(2):206-12. Epub 2013 Aug 15.

Department of Medical Genetics, Bahcesehir University School of Medicine, Istanbul, Turkey,

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http://dx.doi.org/10.1007/s12020-013-0027-7DOI Listing
March 2014

Mild and severe congenital primary hypothyroidism in two patients by thyrotropin receptor (TSHR) gene mutation.

J Pediatr Endocrinol Metab 2012 ;25(11-12):1153-6

Clinics of Pediatric Endocrinoloy, Dr. Sami Ulus Women Health, Children's Training and Research Hospital, Ankara 06080, Turkey.

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http://dx.doi.org/10.1515/jpem-2012-0211DOI Listing
March 2013

Turkish perspective of Jervell and Lange-Nielsen syndrome.

Ann Indian Acad Neurol 2013 Jan;16(1):129-30

Department of Medical Genetics, University of Uludag, Faculty of Medicine, Bursa ; Department of Histology and Embryology, University of Near East, Faculty of Medicine, Lefkosia, North Cyprus, Turkey.

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http://dx.doi.org/10.4103/0972-2327.107703DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3644775PMC
January 2013

Puberty, stress, and sudden death.

Lancet 2010 Oct;376(9751):1512

Department of Endocrinology and Metabolism, School of Medicine, Uludag University, Bursa, Turkey.

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http://dx.doi.org/10.1016/S0140-6736(10)61153-1DOI Listing
October 2010

Association of urokinase gene 3'-UTR T/C polymorphism with calcium oxalate urolithiasis in children.

Int Urol Nephrol 2008 1;40(3):563-8. Epub 2008 Feb 1.

Department of Urology, Uludag University School of Medicine, Bursa, Turkey.

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http://dx.doi.org/10.1007/s11255-008-9335-xDOI Listing
January 2009

Hypoxia upregulates the expression of the NDRG1 gene leading to its overexpression in various human cancers.

Authors:
Hakan Cangul

BMC Genet 2004 Sep 2;5:27. Epub 2004 Sep 2.

Department of Medical Genetics, Uludag University School of Medicine, Gorukle, Bursa 16059 Turkey.

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http://dx.doi.org/10.1186/1471-2156-5-27DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC518960PMC
September 2004

Enhanced overexpression of an HIF-1/hypoxia-related protein in cancer cells.

Environ Health Perspect 2002 Oct;110 Suppl 5:783-8

Department of Environmental Medicine, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA.

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http://europepmc.org/articles/pmc1241245/pdf/ehp110s-000783.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1241245PMC
http://dx.doi.org/10.1289/ehp.02110s5783DOI Listing
October 2002