Hakan Alakus

Hakan Alakus

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Hakan Alakus

Hakan Alakus

Publications by authors named "Hakan Alakus"

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Upregulation of miR-17-92 cluster is associated with progression and lymph node metastasis in oesophageal adenocarcinoma.

Sci Rep 2019 Aug 20;9(1):12113. Epub 2019 Aug 20.

Department of General, Visceral and Cancer Surgery, University of Cologne, Faculty of Medicine and University Hospital Cologne, Kerpener Straße 62, D-50937, Cologne, Germany.

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http://dx.doi.org/10.1038/s41598-019-48624-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702344PMC
August 2019

Stellenwert der MRT in der Differenzialdiagnose des akuten Abdomens einer Schwangeren – Placenta percreta mit akuter, hämodynamisch relevanter Blutung.

Rofo 2019 Jul 30. Epub 2019 Jul 30.

Universität zu Köln, Medizinische Fakultät und Uniklinik Köln, Institut für Diagnostische und Interventionelle Radiologie.

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http://dx.doi.org/10.1055/a-0966-8977DOI Listing
July 2019

[Flap Reconstruction as Alternative Anastomosis Technique for the Surgery of Oesophageal Atresia with Distal Oesophagotracheal Fistula].

Zentralbl Chir 2019 Apr 15;144(2):135-136. Epub 2019 Jan 15.

Allgemein-, Viszeral- und Tumorchirurgie, Universitätsklinikum Köln, Deutschland.

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http://dx.doi.org/10.1055/a-0800-0216DOI Listing
April 2019

Outcome of Self-Expanding Metal Stents in the Treatment of Anastomotic Leaks After Ivor Lewis Esophagectomy.

World J Surg 2019 Mar;43(3):862-869

Department of General, Visceral and Cancer Surgery, University Hospital of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.

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http://link.springer.com/10.1007/s00268-018-4832-2
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http://dx.doi.org/10.1007/s00268-018-4832-2DOI Listing
March 2019

Self-Expanding Metal Stents Versus Endoscopic Vacuum Therapy in Anastomotic Leak Treatment After Oncologic Gastroesophageal Surgery.

J Gastrointest Surg 2019 Jan 29;23(1):67-75. Epub 2018 Oct 29.

Department of General, Visceral and Cancer Surgery, University Hospital of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.

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http://link.springer.com/10.1007/s11605-018-4000-x
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http://dx.doi.org/10.1007/s11605-018-4000-xDOI Listing
January 2019

Tumour-infiltrating neutrophils counteract anti-VEGF therapy in metastatic colorectal cancer.

Br J Cancer 2019 01 31;120(1):69-78. Epub 2018 Oct 31.

Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Center for Molecular Medicine Cologne (CMMC) and Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne, CECAD Research Center, Joseph-Stelzmann-Str. 26, 50931, Cologne, Germany.

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http://www.nature.com/articles/s41416-018-0198-3
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http://dx.doi.org/10.1038/s41416-018-0198-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325148PMC
January 2019

The upregulation of hypoxia-related miRNA 210 in primary tumor of lymphogenic metastatic prostate cancer.

Epigenomics 2018 10 15;10(10):1347-1359. Epub 2018 Aug 15.

Laboratory for Molecular Oncology, University Hospital of Cologne, Kerpener Strasse 62, D-50937 Cologne, Germany.

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http://dx.doi.org/10.2217/epi-2017-0114DOI Listing
October 2018

Prognosis of patients with superficial T1 esophageal cancer who underwent endoscopic resection before esophagectomy-A propensity score-matched comparison.

Surg Endosc 2018 09 13;32(9):3972-3980. Epub 2018 Mar 13.

Department of General, Visceral and Cancer Surgery, University Hospital of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1007/s00464-018-6139-7DOI Listing
September 2018

Postoperative granulomatous peritonitis mimicking abdominal tuberculosis.

Clin Case Rep 2018 Sep 25;6(9):1810-1814. Epub 2018 Jul 25.

Department I of Internal Medicine University Hospital of Cologne Cologne Germany.

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http://dx.doi.org/10.1002/ccr3.1724DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132106PMC
September 2018

Update on Transumbilical Single-Incision Laparoscopic Assisted Appendectomy (TULAA) - Which Children Benefit and What are the Complications?

Klin Padiatr 2018 Jul 15;230(4):194-199. Epub 2018 Mar 15.

Division of Pediatric Surgery, University Hospital Cologne, Köln, Germany.

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http://dx.doi.org/10.1055/s-0044-101622DOI Listing
July 2018

[Lung Metastasectomy in Pulmonary Metastatic Colorectal Carcinoma].

Zentralbl Chir 2018 Apr 25;143(2):193-204. Epub 2017 Sep 25.

Klinik und Poliklinik für Herz- und Thoraxchirurgie, Universitätsklinikum Köln, Deutschland.

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http://dx.doi.org/10.1055/s-0043-114734DOI Listing
April 2018

Results of endoscopic vacuum-assisted closure device for treatment of upper GI leaks.

Surg Endosc 2018 04 7;32(4):1906-1914. Epub 2017 Dec 7.

Department of General, Visceral and Cancer Surgery, University of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.

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http://dx.doi.org/10.1007/s00464-017-5883-4DOI Listing
April 2018

Copy-number variation and protein expression of DOT1L in pancreatic adenocarcinoma as a potential drug target.

Mol Clin Oncol 2017 May 14;6(5):639-642. Epub 2017 Mar 14.

Institute of Pathology, University of Cologne, Gastrointestinal Cancer Group Cologne, D-50937 Cologne, Germany.

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http://dx.doi.org/10.3892/mco.2017.1194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432215PMC
May 2017

Molecular Markers for the Prediction of Minor Response to Neoadjuvant Chemoradiation in Esophageal Cancer: Results of the Prospective Cologne Esophageal Response Prediction (CERP) Study.

Ann Surg 2016 Nov;264(5):839-846

Department of General, Visceral and Cancer Surgery, University Hospital of Cologne, Institute of Pathology, University Hospital of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1097/SLA.0000000000001911DOI Listing
November 2016

Long-term quality of life after surgery for adenocarcinoma of the esophagogastric junction: extended gastrectomy or transthoracic esophagectomy?

Gastric Cancer 2016 Jan 28;19(1):312-7. Epub 2015 Jan 28.

Department of General-, Visceral-, and Cancer Surgery, University of Cologne, Kerpener Strasse 62, 50931, Cologne, Germany.

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http://dx.doi.org/10.1007/s10120-015-0466-3DOI Listing
January 2016

Both GLUT-1 and GLUT-14 are Independent Prognostic Factors in Gastric Adenocarcinoma.

Ann Surg Oncol 2015 Dec 17;22 Suppl 3:S822-31. Epub 2015 Jul 17.

Department of General, Visceral and Cancer Surgery, University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1245/s10434-015-4730-xDOI Listing
December 2015

Gene Expression of Col11A1 Is a Marker Not only for Pancreas Carcinoma But also for Adenocarcinoma of the Papilla of Vater, Discriminating Between Carcinoma and Chronic Pancreatitis.

Anticancer Res 2015 Nov;35(11):6153-8

General-, Visceral- and Tumor Surgery, Center for Integrated Oncology (CIO), University Hospital of Cologne, Cologne, Germany

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November 2015

Molecular markers predicting lymph node metastasis in early esophageal cancer.

Histol Histopathol 2015 Oct 14;30(10):1193-202. Epub 2015 Apr 14.

Department of General, Visceral and Cancer Surgery, University of Cologne, Germany.

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http://www.hh.um.es/Abstracts/Vol_30/30_10/30_10_1193.htm
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http://dx.doi.org/10.14670/HH-11-618DOI Listing
October 2015

BAP1 mutation is a frequent somatic event in peritoneal malignant mesothelioma.

J Transl Med 2015 Apr 16;13:122. Epub 2015 Apr 16.

Moores UCSD Cancer Center, 3855 Health Science Drive, Maildrop 0820, 92093, La Jolla, USA.

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http://dx.doi.org/10.1186/s12967-015-0485-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422481PMC
April 2015

Network-based analysis identifies epigenetic biomarkers of esophageal squamous cell carcinoma progression.

Bioinformatics 2014 Nov 10;30(21):3054-61. Epub 2014 Jul 10.

Department of Computer Science and Information Engineering, National Cheng Kung University, Tainan 701, Taiwan, Moores Cancer Center, University of California San Diego, La Jolla, CA 92093, USA, Institute of Basic Medical Sciences, National Cheng Kung University, Tainan 701, Taiwan, Department of Pediatrics and Rady Children's Hospital, University of California San Diego, La Jolla, CA 92093, USA, Department of General, Visceral and Cancer Surgery, University of Cologne, Köln, Germany, Institute for Genomic Medicine, University of California San Diego, La Jolla, CA 92093, USA, Department of Pharmacology and Institute of Medical Informatics, National Cheng Kung University, Tainan 701, Taiwan Department of Computer Science and Information Engineering, National Cheng Kung University, Tainan 701, Taiwan, Moores Cancer Center, University of California San Diego, La Jolla, CA 92093, USA, Institute of Basic Medical Sciences, National Cheng Kung University, Tainan 701, Taiwan, Department of Pediatrics and Rady Children's Hospital, University of California San Diego, La Jolla, CA 92093, USA, Department of General, Visceral and Cancer Surgery, University of Cologne, Köln, Germany, Institute for Genomic Medicine, University of California San Diego, La Jolla, CA 92093, USA, Department of Pharmacology and Institute of Medical Informatics, National Cheng Kung University, Tainan 701, Taiwan.

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http://dx.doi.org/10.1093/bioinformatics/btu433DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609006PMC
November 2014

Correction: Genome-wide mutational landscape of mucinous carcinomatosis peritonei of appendiceal origin.

Genome Med 2014 26;6(7):53. Epub 2014 Jul 26.

Division of Genome Information Sciences, Department of Pediatrics and Rady Children's Hospital, University of California San Diego, La Jolla, CA USA ; Moores UCSD Cancer Center, University of California San Diego, La Jolla, CA USA ; Clinical and Translational Science Institute, University of California San Diego, La Jolla, CA USA.

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http://dx.doi.org/10.1186/s13073-014-0053-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165363PMC
September 2014

Validation of 2-mm tissue microarray technology in gastric cancer. Agreement of 2-mm TMAs and full sections for Glut-1 and Hif-1 alpha.

Anticancer Res 2014 Jul;34(7):3313-20

Department of General, Visceral and Cancer Surgery, University of Cologne, Cologne, Germany Department of Pathology, University of Cologne, Cologne, Germany Division of Genome information Sciences, Department of Pediatrics and Rady Children's Hospital, University of California San Diego, La Jolla, CA, U.S.A.

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July 2014

Genome-wide mutational landscape of mucinous carcinomatosis peritonei of appendiceal origin.

Genome Med 2014 29;6(5):43. Epub 2014 May 29.

Division of Genome Information Sciences, Department of Pediatrics and Rady Children's Hospital, University of California San Diego, La Jolla, CA, USA ; Moores UCSD Cancer Center, University of California San Diego, La Jolla, CA, USA ; Clinical and Translational Science Institute, University of California San Diego, La Jolla, CA, USA.

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http://dx.doi.org/10.1186/gm559DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062050PMC
June 2014

Mutascope: sensitive detection of somatic mutations from deep amplicon sequencing.

Bioinformatics 2013 Aug 27;29(15):1908-9. Epub 2013 May 27.

Bioinformatics Graduate Program, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, USA.

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http://dx.doi.org/10.1093/bioinformatics/btt305DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712217PMC
August 2013

Neoadjuvant radiochemotherapy in adenocarcinoma of the esophagus: ERCC1 gene polymorphisms for prediction of response and prognosis.

J Gastrointest Surg 2012 Jan 29;16(1):26-34; discussion 34. Epub 2011 Sep 29.

Department of General, Visceral and Cancer Surgery, Center for Integrated Oncology (CIO Cologne Bonn), University Hospital of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1007/s11605-011-1700-xDOI Listing
January 2012

Impact of ABCB1 C3435T polymorphism on lymph node regression in multimodality treatment of locally advanced esophageal cancer.

Pharmacogenomics 2011 Feb;12(2):205-14

Department of General, Visceral & Cancer Surgery, Center for Integrated Oncology (CIO), University of Cologne, Kerpener Strasse 62, 50937 Cologne, Germany.

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http://dx.doi.org/10.2217/pgs.10.174DOI Listing
February 2011

Clinical impact of MMP and TIMP gene polymorphisms in gastric cancer.

World J Surg 2010 Dec;34(12):2853-9

Department of General, Visceral and Cancer Surgery, Center for Integrated Oncology, University of Cologne, Kerpenerstrasse 62, 50937, Cologne, Germany.

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http://dx.doi.org/10.1007/s00268-010-0761-4DOI Listing
December 2010

Neoadjuvant chemoradiotherapy for esophageal cancer: impact on extracapsular lymph node involvement.

World J Gastroenterol 2010 Apr;16(16):1986-92

Department of General, Visceral and Cancer Surgery, Center for Integrated Oncology, University Hospital of Cologne, Kerpener Strasse 62, Cologne, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860075PMC
http://dx.doi.org/10.3748/wjg.v16.i16.1986DOI Listing
April 2010

Extracapsular lymph node spread: a new prognostic factor in gastric cancer.

Cancer 2010 Jan;116(2):309-15

Department of General, Visceral and Cancer Surgery, University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1002/cncr.24764DOI Listing
January 2010

Association of the GNAS1 T393C polymorphism with tumor stage and survival in gastric cancer.

World J Gastroenterol 2009 Dec;15(48):6061-7

Department of General, Visceral and Cancer Surgery, Center for Integrated Oncology, University Hospital of Cologne, Kerpener Str. 62, D-50937 Cologne, Germany.

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http://www.wjgnet.com/1007-9327/15/6061.pdf
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797662PMC
http://dx.doi.org/10.3748/wjg.15.6061DOI Listing
December 2009

Combined analysis of hypoxia-inducible factor 1 alpha and metallothionein indicates an aggressive subtype of colorectal carcinoma.

Int J Colorectal Dis 2009 Nov 16;24(11):1287-96. Epub 2009 Jun 16.

Institute of Pathology and Neuropathology, University Hospital Essen, University of Duisburg-Essen, Hufelandstr. 55, 45122 Essen, Germany.

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http://dx.doi.org/10.1007/s00384-009-0753-8DOI Listing
November 2009

ERCC1 and XRCC1 gene polymorphisms predict response to neoadjuvant radiochemotherapy in esophageal cancer.

J Gastrointest Surg 2009 Aug 7;13(8):1411-21. Epub 2009 May 7.

Department of General, Visceral, and Cancer Surgery, Center for Integrated Oncology, University Hospital of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.

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http://dx.doi.org/10.1007/s11605-009-0881-zDOI Listing
August 2009

Association of GNB4 intron-1 haplotypes with survival in patients with UICC stage III and IV colorectal carcinoma.

Anticancer Res 2009 Apr;29(4):1271-4

University Hospital Essen, Hufelandstr. 55, 45147 Essen, Germany.

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April 2009