Haiyong Han

Haiyong Han

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Haiyong Han

Publications by authors named "Haiyong Han"

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Ultra-Sensitive Automated Profiling of EpCAM Expression on Tumor-Derived Extracellular Vesicles.

Front Genet 2019 17;10:1273. Epub 2019 Dec 17.

Virginia G. Piper Biodesign Center for Personalized Diagnostics, The Biodesign Institute, Arizona State University, Tempe, AZ, United States.

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http://dx.doi.org/10.3389/fgene.2019.01273DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928048PMC
December 2019

Chemoresistance Transmission via Exosome-Mediated EphA2 Transfer in Pancreatic Cancer.

Theranostics 2018 13;8(21):5986-5994. Epub 2018 Nov 13.

School of Biological and Health Systems Engineering, Virginia G. Piper Biodesign Center for Personalized Diagnostics, The Biodesign Institute, Arizona State University, Tempe, AZ 85281, USA.

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http://www.thno.org/v08p5986.htm
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http://dx.doi.org/10.7150/thno.26650DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299429PMC
September 2019

Single-Cell Sequencing in Precision Medicine.

Cancer Treat Res 2019 ;178:237-252

Molecular Medicine Division, Translational Genomics Research Institute, Phoenix, AZ, USA.

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http://dx.doi.org/10.1007/978-3-030-16391-4_9DOI Listing
June 2019

Triptolide and Its Derivatives as Cancer Therapies.

Trends Pharmacol Sci 2019 05 8;40(5):327-341. Epub 2019 Apr 8.

Molecular Medicine Division, Translational Genomics Research Institute, Phoenix, AZ, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01656147193004
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http://dx.doi.org/10.1016/j.tips.2019.03.002DOI Listing
May 2019

A Multiscale Map of the Stem Cell State in Pancreatic Adenocarcinoma.

Cell 2019 04 4;177(3):572-586.e22. Epub 2019 Apr 4.

Department of Pharmacology, University of California, San Diego School of Medicine, La Jolla, CA, USA; Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA; Moores Cancer Center, University of California, San Diego School of Medicine, La Jolla, CA, USA; Department of Medicine, University of California, San Diego School of Medicine, La Jolla, CA, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00928674193027
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http://dx.doi.org/10.1016/j.cell.2019.03.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711371PMC
April 2019

Dosage of Atg5 Gene Affects Pancreatic Tumorigenesis and Progression.

Authors:
Haiyong Han

Gastroenterology 2019 01 22;156(1):17-19. Epub 2018 Nov 22.

Molecular Medicine Division, Translational Genomics Research Institute, Phoenix, Arizona. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00165085183528
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http://dx.doi.org/10.1053/j.gastro.2018.11.038DOI Listing
January 2019

A DNA Polymerase Stop Assay for Characterization of G-Quadruplex Formation and Identification of G-Quadruplex-Interactive Compounds.

Methods Mol Biol 2019 ;2035:223-231

Molecular Medicine Division, Translational Genomics Research Institute, Phoenix, AZ, USA.

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http://dx.doi.org/10.1007/978-1-4939-9666-7_12DOI Listing
January 2019

KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism.

Cancer Cell 2018 11;34(5):807-822.e7

Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. Electronic address:

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https://www.researchgate.net/publication/325458004_KRAS_Supp
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http://scholar.google.fi/citations?user=_42T_HMAAAAJ&hl=en
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https://www.journals.elsevier.com/cancer-cell/recent-article
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https://linkinghub.elsevier.com/retrieve/pii/S15356108183046
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http://dx.doi.org/10.1016/j.ccell.2018.10.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321749PMC
November 2018

RNA Interference to Knock Down Gene Expression.

Authors:
Haiyong Han

Methods Mol Biol 2018 ;1706:293-302

Translational Genomics Research Institute, 445. N. Fifth St., Suite 400, Phoenix, AZ, 85004, USA.

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http://dx.doi.org/10.1007/978-1-4939-7471-9_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743327PMC
October 2018

The Effects of Synthetically Modified Natural Compounds on ABC Transporters.

Pharmaceutics 2018 Aug 9;10(3). Epub 2018 Aug 9.

School of Science, Auckland University of Technology, Auckland 1010, New Zealand.

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http://dx.doi.org/10.3390/pharmaceutics10030127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161255PMC
August 2018

Pixantrone: novel mode of action and clinical readouts.

Expert Rev Hematol 2018 07 18;11(7):587-596. Epub 2018 Jun 18.

d Istituto Oncologico di Ricerca , Università della Svizzera italiana , Bellinzona , Switzerland.

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http://dx.doi.org/10.1080/17474086.2018.1476848DOI Listing
July 2018

Pancreatic acinar cell carcinoma: A review on molecular profiling of patient tumors.

World J Gastroenterol 2017 Dec;23(45):7945-7951

Molecular Medicine Division, Translational Genomics Research Institute (TGen), Phoenix, AZ 85004, United States.

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http://dx.doi.org/10.3748/wjg.v23.i45.7945DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725289PMC
December 2017

Inhibition of ROCK1 kinase modulates both tumor cells and stromal fibroblasts in pancreatic cancer.

PLoS One 2017 25;12(8):e0183871. Epub 2017 Aug 25.

Molecular Medicine Division, The Translational Genomics Research Institute, Phoenix, Arizona, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0183871PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571985PMC
October 2017

Curcumin sensitizes pancreatic cancer cells to gemcitabine by attenuating PRC2 subunit EZH2, and the lncRNA PVT1 expression.

Carcinogenesis 2017 10;38(10):1036-1046

Center for Gastrointestinal Research, Center for Translational Genomics and Oncology, Baylor Scott and White Research Institute and Charles A. Sammons Cancer Center, Baylor University Medical Center, Dallas, TX 75246, USA.

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https://academic.oup.com/carcin/article/38/10/1036/3924866
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http://dx.doi.org/10.1093/carcin/bgx065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862331PMC
October 2017

Blocking Nerve Growth Factor Signaling Reduces the Neural Invasion Potential of Pancreatic Cancer Cells.

PLoS One 2016 28;11(10):e0165586. Epub 2016 Oct 28.

Clinical Translational Research Division, Translational Genomics Research Institute, Phoenix, Arizona, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0165586PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085053PMC
June 2017

Orchestrating the Tumor Microenvironment to Improve Survival for Patients With Pancreatic Cancer: Normalization, Not Destruction.

Cancer J 2015 Jul-Aug;21(4):299-306

From the Clinical Translational Research Division, The Translational Genomics Research Institute (TGen), Phoenix, AZ.

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http://dx.doi.org/10.1097/PPO.0000000000000140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817719PMC
May 2016

Adenosquamous carcinoma of the pancreas: Molecular characterization of 23 patients along with a literature review.

World J Gastrointest Oncol 2015 Sep;7(9):132-40

Erkut Borazanci, Daniel D Von Hoff, HonorHealth Research Institute, Virginia G. Piper Cancer Center, Scottsdale, AZ 85258, United States.

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http://dx.doi.org/10.4251/wjgo.v7.i9.132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569590PMC
September 2015

Desmoplasia in Primary Tumors and Metastatic Lesions of Pancreatic Cancer.

Clin Cancer Res 2015 Aug 18;21(15):3561-8. Epub 2015 Feb 18.

Clinical Translational Research Division, The Translational Genomics Research Institute, Phoenix, Arizona.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-1051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526394PMC
August 2015

Therapeutic melting pot of never in mitosis gene a related kinase 2 (Nek2): a perspective on Nek2 as an oncology target and recent advancements in Nek2 small molecule inhibition.

J Med Chem 2014 Jul 25;57(14):5835-44. Epub 2014 Feb 25.

Department of Pharmacoloy and Toxicology, College of Pharmacy, The University of Arizona , Tucson, Arizona 85721, United States.

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http://dx.doi.org/10.1021/jm401719nDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666018PMC
July 2014

Discrimination between adenocarcinoma and normal pancreatic ductal fluid by proteomic and glycomic analysis.

J Proteome Res 2014 Feb 12;13(2):395-407. Epub 2013 Dec 12.

Complex Carbohydrate Research Center, ‡Chemistry Department, and §Department of Biochemistry and Molecular Biology, University of Georgia , Athens, Georgia 30602, United States.

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http://dx.doi.org/10.1021/pr400422gDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946306PMC
February 2014

Tumor-stromal interactions in pancreatic cancer.

Crit Rev Oncog 2013 ;18(1-2):135-51

Clinical Translational Research Division, The Translational Genomics Research Institute (TGEN), Phoenix, Arizona 85004, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3632415PMC
http://dx.doi.org/10.1615/critrevoncog.v18.i1-2.80DOI Listing
July 2013

Characterization of a membrane-active anti-tumor agent, UA8967.

Invest New Drugs 2013 Jun 23;31(3):576-86. Epub 2012 Nov 23.

University of Arizona Cancer Center, 1515 N. Campbell Ave, Rm 4963C, Tucson, AZ 85724-5024, USA.

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http://dx.doi.org/10.1007/s10637-012-9901-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3624034PMC
June 2013

Isolation and characterization of muscle fatigue substance with anti-tumor activities.

J Cancer 2013 9;4(4):343-9. Epub 2013 May 9.

Division of Clinical Translational Research, Translational Genomics Research Institute, Scottsdale, Arizona, USA.

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http://dx.doi.org/10.7150/jca.5418DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654491PMC
May 2013

SnapShot: pancreatic cancer.

Cancer Cell 2013 Mar;23(3):424-424.e1

Translational Genomics Research Institute, Phoenix, AZ 85004, USA.

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http://dx.doi.org/10.1016/j.ccr.2013.03.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638898PMC
March 2013

Molecular Characterization of a Patient's Small Cell Carcinoma of the Ovary of the Hypercalcemic Type.

J Cancer 2012 26;3:58-66. Epub 2012 Jan 26.

1. Clinical Translational Research Division, Translational Genomics Research Institute, Phoenix, AZ, USA.

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http://dx.doi.org/10.7150/jca.3872DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273708PMC
October 2012

Kinome-wide siRNA screening identifies molecular targets mediating the sensitivity of pancreatic cancer cells to Aurora kinase inhibitors.

Biochem Pharmacol 2012 Feb 15;83(4):452-61. Epub 2011 Nov 15.

Clinical Translational Research Division, Translational Genomic Research Institute (TGen), 13208 E Shea Blvd, Scottsdale, AZ 85259, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S000629521100822
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http://dx.doi.org/10.1016/j.bcp.2011.11.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265162PMC
February 2012

Perineural invasion and associated pain in pancreatic cancer.

Nat Rev Cancer 2011 Sep 23;11(10):695-707. Epub 2011 Sep 23.

Clinical Translational Research Division, Translational Genomics Research Institute, 13208 East Shea Boulevard, Scottsdale, Arizona 85259, USA.

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http://dx.doi.org/10.1038/nrc3131DOI Listing
September 2011

Targeting the tumor microenvironment in cancer: why hyaluronidase deserves a second look.

Cancer Discov 2011 Sep;1(4):291-6

Clinical Translational Research Division, The Translational Genomics Research Institute, Phoenix, Arizona, USA.

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http://dx.doi.org/10.1158/2159-8290.CD-11-0136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204883PMC
September 2011

Synergistic effect between erlotinib and MEK inhibitors in KRAS wild-type human pancreatic cancer cells.

Clin Cancer Res 2011 May 8;17(9):2744-56. Epub 2011 Mar 8.

Clinical Translational Research Division, Translational Genomics Research Institute, Scottsdale, Arizona 85259, USA.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-10-2214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265169PMC
May 2011

Cell cycle arrest and apoptosis induction by an anticancer chalcone epoxide.

Arch Pharm (Weinheim) 2010 Aug;343(8):429-39

Translational Genomics Research Institute, Phoenix, AZ 85004, USA.

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http://dx.doi.org/10.1002/ardp.200900261DOI Listing
August 2010

Identification of pancreatic cancer-specific cell-surface markers for development of targeting ligands.

Methods Mol Biol 2010 ;624:195-210

Molecular and Functional Imaging, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.

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http://dx.doi.org/10.1007/978-1-60761-609-2_13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010309PMC
June 2010

Validation of TPX2 as a potential therapeutic target in pancreatic cancer cells.

Clin Cancer Res 2009 Nov 27;15(21):6519-28. Epub 2009 Oct 27.

Clinical Translational Research Division, Translational Genomics Research Institute, Phoenix, Arizona 85004, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-09-0077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783218PMC
November 2009

Enhanced targeting with heterobivalent ligands.

Mol Cancer Ther 2009 Aug 11;8(8):2356-65. Epub 2009 Aug 11.

Department of Pharmaceutical Analytics, Pharmaceutical Institute, University of Tuebingen, Tuebingen, Germany.

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http://dx.doi.org/10.1158/1535-7163.MCT-08-1183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662534PMC
August 2009

Identification and characterization of a novel anticancer agent with selectivity against deleted in pancreatic cancer locus 4 (DPC4)-deficient pancreatic and colon cancer cells.

Pancreas 2009 Jul;38(5):551-7

Clinical Translational Research Division, Translational Genomics Research Institute, Phoenix, AZ 85004, USA.

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http://dx.doi.org/10.1097/MPA.0b013e31819d7415DOI Listing
July 2009

UA62784, a novel inhibitor of centromere protein E kinesin-like protein.

Mol Cancer Ther 2009 Jan;8(1):36-44

Arizona Cancer Center, BIO5 Institute, College of Pharmacy, University of Arizona, 1515 North Campbell Avenue, Tucson, AZ 85724-5024, USA.

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http://mct.aacrjournals.org/cgi/doi/10.1158/1535-7163.MCT-08
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http://dx.doi.org/10.1158/1535-7163.MCT-08-0789DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2634858PMC
January 2009

Identification of thioredoxin-interacting protein 1 as a hypoxia-inducible factor 1alpha-induced gene in pancreatic cancer.

Pancreas 2008 Mar;36(2):178-86

College of Medicine, Hematology/Oncology, Arizona Cancer Center, University of Arizona, Tucson, AZ 85724, USA.

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http://dx.doi.org/10.1097/MPA.0b013e31815929feDOI Listing
March 2008

Small interfering RNA-mediated knockdown of PRL phosphatases results in altered Akt phosphorylation and reduced clonogenicity of pancreatic cancer cells.

Mol Cancer Ther 2008 Jan 9;7(1):202-10. Epub 2008 Jan 9.

Department of Molecular and Cellular Biology, University of Arizona, Tucson, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-07-0542DOI Listing
January 2008

Identification of a novel inhibitor of urokinase-type plasminogen activator.

Mol Cancer Ther 2007 Apr;6(4):1348-56

Division of Clinical Translational Research, Translational Genomics Research Institute, Phoenix, AZ 85004, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-06-0520DOI Listing
April 2007

Identification of an agent selectively targeting DPC4 (deleted in pancreatic cancer locus 4)-deficient pancreatic cancer cells.

Cancer Res 2006 Oct;66(19):9722-30

Pancreatic Cancer Research Laboratory, Clinical Translational Research Division, Translational Genomics Research Institute, Phoenix, AZ 85004, USA.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-05-4602DOI Listing
October 2006

Comparing Aurora A and Aurora B as molecular targets for growth inhibition of pancreatic cancer cells.

Mol Cancer Ther 2006 Oct;5(10):2450-8

College of Pharmacy, University of Arizona, Tucson, Arizona, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-06-0202DOI Listing
October 2006

Aurora sheds light on head and neck squamous cell carcinoma.

Clin Cancer Res 2006 Sep;12(17):5003-4

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http://dx.doi.org/10.1158/1078-0432.CCR-06-1329DOI Listing
September 2006

Targeting loss-of-function mutations in tumor-suppressor genes as a strategy for development of cancer therapeutic agents.

Semin Oncol 2006 Aug;33(4):513-20

The Translational Genomics Research Institute, Translational Drug Development Division, Phoenix, AZ 85004, USA.

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http://dx.doi.org/10.1053/j.seminoncol.2006.04.013DOI Listing
August 2006

PRL phosphatases as potential molecular targets in cancer.

Mol Cancer Ther 2005 Nov;4(11):1653-61

Department of Molecular and Cellular Biology, University of Arizona, Tucson, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-05-0248DOI Listing
November 2005

Hitting multiple targets with multimeric ligands.

Expert Opin Ther Targets 2004 Dec;8(6):565-86

Arizona Cancer Center, Department of Biochemistry and Molecular Biophysics, 1515 N. Campbell Avenue, Tucson, AZ 85724-5024, USA.

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http://dx.doi.org/10.1517/14728222.8.6.565DOI Listing
December 2004

The mitotic serine threonine kinase, Aurora-2, is a potential target for drug development in human pancreatic cancer.

Mol Cancer Ther 2004 Apr;3(4):451-7

Arizona Cancer Center, University of Arizona, Tucson, AZ 85724, USA.

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April 2004

Targeting Aurora-2 kinase in cancer.

Mol Cancer Ther 2003 Jun;2(6):589-95

Arizona Cancer Center, University of Arizona, Tucson, Arizona 85724, USA.

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June 2003

Identification of differentially expressed genes in pancreatic cancer cells using cDNA microarray.

Cancer Res 2002 May;62(10):2890-6

Department of Pathology, Arizona Cancer Center, University of Arizona, Tucson, AZ 85724, USA.

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May 2002