Hailing Lu

Hailing Lu

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Hailing Lu

Hailing Lu

Publications by authors named "Hailing Lu"

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Tumor-associated antigens identified early in mouse mammary tumor development can be effective vaccine targets.

Vaccine 2019 Jun 21;37(27):3552-3561. Epub 2019 May 21.

Cancer Vaccine Institute, University of Washington, Seattle WA, 98109, USA.

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http://dx.doi.org/10.1016/j.vaccine.2019.05.024DOI Listing
June 2019

Mammalian Eps15 homology domain 1 potentiates angiogenesis of non-small cell lung cancer by regulating β2AR signaling.

J Exp Clin Cancer Res 2019 Apr 25;38(1):174. Epub 2019 Apr 25.

The Fourth Department of Medical Oncology, Harbin Medical University Cancer Hospital, 150 Haping Road, Harbin, 150040, China.

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https://jeccr.biomedcentral.com/articles/10.1186/s13046-019-
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http://dx.doi.org/10.1186/s13046-019-1162-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482525PMC
April 2019

miR-181b/Notch2 overcome chemoresistance by regulating cancer stem cell-like properties in NSCLC.

Stem Cell Res Ther 2018 11 23;9(1):327. Epub 2018 Nov 23.

The Department of Internal Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, Heilongjiang Province, China.

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http://dx.doi.org/10.1186/s13287-018-1072-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260863PMC
November 2018

USP22 promotes resistance to EGFR-TKIs by preventing ubiquitination-mediated EGFR degradation in EGFR-mutant lung adenocarcinoma.

Cancer Lett 2018 10 4;433:186-198. Epub 2018 Jul 4.

The 4th Department of Internal Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, Heilongjiang, China. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2018.07.002DOI Listing
October 2018

Overexpression of 14-3-3ζ in lung tissue predicts an improved outcome in patients with lung adenocarcinoma.

Oncol Lett 2018 Jul 18;16(1):1051-1058. Epub 2018 May 18.

The Fourth Department of Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, Heilongjiang 150040, P.R. China.

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http://dx.doi.org/10.3892/ol.2018.8742DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019889PMC
July 2018

TNFAIP8 promotes the proliferation and cisplatin chemoresistance of non-small cell lung cancer through MDM2/p53 pathway.

Cell Commun Signal 2018 07 31;16(1):43. Epub 2018 Jul 31.

The Fourth Department of Medical Oncology, Harbin Medical University Cancer Hospital, 150 Haping Road, Harbin, 150040, China.

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http://dx.doi.org/10.1186/s12964-018-0254-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069800PMC
July 2018

NF-κB-driven improvement of EHD1 contributes to erlotinib resistance in EGFR-mutant lung cancers.

Cell Death Dis 2018 04 1;9(4):418. Epub 2018 Apr 1.

The Department of Internal Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, China.

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http://dx.doi.org/10.1038/s41419-018-0447-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856828PMC
April 2018

TLR8 ligation induces apoptosis of monocytic myeloid-derived suppressor cells.

J Leukoc Biol 2018 01 14;103(1):157-164. Epub 2017 Dec 14.

Tumor Vaccine Group, Center for Translational Medicine in Women's Health, University of Washington, Seattle, Washington, USA.

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http://doi.wiley.com/10.1002/JLB.5AB0217-070R
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http://dx.doi.org/10.1002/JLB.5AB0217-070RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721845PMC
January 2018

First-in-Human Treatment With a Dendritic Cell-targeting Lentiviral Vector-expressing NY-ESO-1, LV305, Induces Deep, Durable Response in Refractory Metastatic Synovial Sarcoma Patient.

J Immunother 2017 10;40(8):302-306

*Clinical Research Division, Fred Hutchinson Cancer Research Center Department of †Medicine ¶Radiology, University of Washington, Seattle, WA ‡Immune Design, Seattle, WA, and South San Francisco, CA §Mount Sinai School of Medicine, Tisch Cancer Institute, New York, NY ∥MD Anderson Cancer Center, Houston, TX #Royal Marsden Hospital/Institute of Cancer Research, London, England.

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http://dx.doi.org/10.1097/CJI.0000000000000183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733794PMC
October 2017

14-3-3ζ/TGFβR1 promotes tumor metastasis in lung squamous cell carcinoma.

Oncotarget 2016 Dec;7(50):82972-82984

The Department of Internal Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, Heilongjiang Province, China.

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http://dx.doi.org/10.18632/oncotarget.12690DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347746PMC
December 2016

Significant Correlation between TLR2 Agonist Activity and TNF-α Induction in J774.A1 Macrophage Cells by Different Medicinal Mushroom Products.

Int J Med Mushrooms 2015 ;17(8):713-22

Tumor Vaccine Group, Department of Medicine, University of Washington, Seattle, WA, USA.

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http://www.dl.begellhouse.com/download/article/34fa1edb20739
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August 2016

Efficacy and Safety of Nedaplatin in Advanced Breast Cancer Therapy.

Cancer Invest 2016 8;34(4):167-72. Epub 2016 Apr 8.

a Department of Internal Medical Oncology , Harbin Medical University Cancer Hospital , Harbin , China.

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http://dx.doi.org/10.3109/07357907.2016.1144061DOI Listing
August 2016

Overexpression of Sphk2 is associated with gefitinib resistance in non-small cell lung cancer.

Tumour Biol 2016 May 1;37(5):6331-6. Epub 2015 Dec 1.

The Fourth Department of Medical Oncology, Harbin Medical University Cancer Hospital, Haping Road 150, Harbin, 150040, People's Republic of China.

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http://link.springer.com/10.1007/s13277-015-4480-1
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http://dx.doi.org/10.1007/s13277-015-4480-1DOI Listing
May 2016

MiR-181b regulates cisplatin chemosensitivity and metastasis by targeting TGFβR1/Smad signaling pathway in NSCLC.

Sci Rep 2015 Dec 1;5:17618. Epub 2015 Dec 1.

Department of Internal Medical Oncology, Harbin medical University Cancer Hospital, Harbin, Heilongjiang Province, China.

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http://dx.doi.org/10.1038/srep17618DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664936PMC
December 2015

USP22 promotes tumor progression and induces epithelial-mesenchymal transition in lung adenocarcinoma.

Lung Cancer 2015 Jun 10;88(3):239-45. Epub 2015 Mar 10.

The 4th Department of Internal Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, Heilongjiang, China. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2015.02.019DOI Listing
June 2015

The TLR2 agonist in polysaccharide-K is a structurally distinct lipid which acts synergistically with the protein-bound β-glucan.

J Nat Med 2015 Apr 16;69(2):198-208. Epub 2014 Dec 16.

Tumor Vaccine Group, Department of Medicine, University of Washington, 850 Republican Street, Seattle, WA, 98109, USA,

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http://dx.doi.org/10.1007/s11418-014-0879-zDOI Listing
April 2015

Protein-bound polysaccharide-K induces IL-1β via TLR2 and NLRP3 inflammasome activation.

Innate Immun 2014 Nov 9;20(8):857-66. Epub 2013 Dec 9.

Tumor Vaccine Group, Center for Translational Medicine in Women's Health, University of Washington, Seattle, WA, USA

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http://dx.doi.org/10.1177/1753425913513814DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414124PMC
November 2014

Ang II-AT1R increases cell migration through PI3K/AKT and NF-κB pathways in breast cancer.

J Cell Physiol 2014 Nov;229(11):1855-62

Department of Internal Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, Heilongjiang Province, China.

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http://doi.wiley.com/10.1002/jcp.24639
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http://dx.doi.org/10.1002/jcp.24639DOI Listing
November 2014

MiR-23a-mediated migration/invasion is rescued by its target, IRS-1, in non-small cell lung cancer cells.

J Cancer Res Clin Oncol 2014 Oct 5;140(10):1661-70. Epub 2014 Jun 5.

The Forth Department of Medicine Oncology, Harbin Medical University Cancer Hospital, Haping Road 150, Harbin, 150040, China.

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http://dx.doi.org/10.1007/s00432-014-1725-0DOI Listing
October 2014

Mining the pre-diagnostic antibody repertoire of TgMMTV-neu mice to identify autoantibodies useful for the early detection of human breast cancer.

J Transl Med 2014 May 10;12:121. Epub 2014 May 10.

Tumor Vaccine Group, Center for Translational Medicine in Women's Health, University of Washington, 850 Republican Street, Box 358050, Seattle, WA 98109, USA.

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http://dx.doi.org/10.1186/1479-5876-12-121DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022541PMC
May 2014

Prognostic values of osteopontin-c, E-cadherin and β-catenin in breast cancer.

Cancer Epidemiol 2013 Dec 5;37(6):985-92. Epub 2013 Sep 5.

Department of Internal Medical Oncology, the Affiliated Tumor Hospital of Harbin Medical University, Harbin, Heilongjiang Province, China.

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http://dx.doi.org/10.1016/j.canep.2013.08.005DOI Listing
December 2013

Increased EHD1 in non-small cell lung cancer predicts poor survival.

Thorac Cancer 2013 Nov;4(4):422-432

The Forth Department of Medical Oncology, The Tumor Hospital of Harbin Medical University, Harbin, China.

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http://doi.wiley.com/10.1111/1759-7714.12043
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http://dx.doi.org/10.1111/1759-7714.12043DOI Listing
November 2013

ABCC3 as a marker for multidrug resistance in non-small cell lung cancer.

Sci Rep 2013 Nov 1;3:3120. Epub 2013 Nov 1.

1] Department of Internal Medical Oncology, the Affiliated Tumor Hospital of Harbin Medical University, Harbin, Heilongjiang Province, China [2].

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http://dx.doi.org/10.1038/srep03120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814586PMC
November 2013

Gamma delta T cells are activated by polysaccharide K (PSK) and contribute to the anti-tumor effect of PSK.

Cancer Immunol Immunother 2013 Aug 18;62(8):1335-45. Epub 2013 May 18.

Tumor Vaccine Group, Center for Translational Medicine in Women's Health, University of Washington, Seattle, WA, USA.

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http://dx.doi.org/10.1007/s00262-013-1436-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3727629PMC
August 2013

The invisible arm of immunity in common cancer chemoprevention agents.

Cancer Prev Res (Phila) 2013 Aug;6(8):764-73

Tumor Vaccine Group, University of Washington, Box 358050, Seattle, WA 98109, USA.

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http://dx.doi.org/10.1158/1940-6207.CAPR-13-0036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3773490PMC
August 2013

Effects of transferrin conjugates of artemisinin and artemisinin dimer on breast cancer cell lines.

Anticancer Res 2013 Jan;33(1):123-32

Department of Chemistry, Box 351700, University of Washington, Seattle, WA 98195-1700, USA.

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http://ar.iiarjournals.org/content/33/1/123.full.pdf
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January 2013

Evaluation of known oncoantibodies, HER2, p53, and cyclin B1, in prediagnostic breast cancer sera.

Cancer Prev Res (Phila) 2012 Aug 19;5(8):1036-43. Epub 2012 Jun 19.

Tumor Vaccine Group, University of Washington, Box 358050, Seattle, WA 98109, USA.

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http://dx.doi.org/10.1158/1940-6207.CAPR-11-0558DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790582PMC
August 2012

VTX-2337 is a novel TLR8 agonist that activates NK cells and augments ADCC.

Clin Cancer Res 2012 Jan 29;18(2):499-509. Epub 2011 Nov 29.

Tumor Vaccine Group, Center for Translational Medicine in Women's Health, University of Washington, Seattle, Washington, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-11-1625DOI Listing
January 2012

TLR2 agonist PSK activates human NK cells and enhances the antitumor effect of HER2-targeted monoclonal antibody therapy.

Clin Cancer Res 2011 Nov 14;17(21):6742-53. Epub 2011 Sep 14.

Tumor Vaccine Group, Center for Translational Medicine in Women's Health, University of Washington, Seattle, Washington 98109, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-11-1142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206987PMC
November 2011

Polysaccharide krestin is a novel TLR2 agonist that mediates inhibition of tumor growth via stimulation of CD8 T cells and NK cells.

Clin Cancer Res 2011 Jan 10;17(1):67-76. Epub 2010 Nov 10.

Tumor Vaccine Group, Center for Translational Medicine in Women's Health, University of Washington, Seattle, Washington 98109, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-10-1763DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017241PMC
January 2011

Treatment failure of a TLR-7 agonist occurs due to self-regulation of acute inflammation and can be overcome by IL-10 blockade.

J Immunol 2010 May 22;184(9):5360-7. Epub 2010 Mar 22.

Tumor Vaccine Group, Center for Translational Medicine in Women's Health, 815 Mercer Street, Room 220, Box 358050, University of Washington, Seattle, WA 98195, USA.

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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.0902997
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http://dx.doi.org/10.4049/jimmunol.0902997DOI Listing
May 2010

Direct detection of carcinoembryonic antigen autoantibodies in clinical human serum samples using a surface plasmon resonance sensor.

Colloids Surf B Biointerfaces 2009 Apr 6;70(1):1-6. Epub 2008 Dec 6.

Department of Chemical Engineering, University of Washington, Seattle, Washington 98195, USA.

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http://dx.doi.org/10.1016/j.colsurfb.2008.11.032DOI Listing
April 2009

FOXP3 expression and prognosis: role of both the tumor and T cells.

Authors:
Hailing Lu

J Clin Oncol 2009 Apr 2;27(11):1735-6. Epub 2009 Mar 2.

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http://dx.doi.org/10.1200/JCO.2008.20.0675DOI Listing
April 2009

Humoral immunity directed against tumor-associated antigens as potential biomarkers for the early diagnosis of cancer.

J Proteome Res 2008 Apr 27;7(4):1388-94. Epub 2008 Feb 27.

Tumor Vaccine Group, Center for Translational Medicine in Women's Health, University of Washington, Seattle, Washington 98109, USA.

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http://pubs.acs.org/doi/abs/10.1021/pr700818f
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http://dx.doi.org/10.1021/pr700818fDOI Listing
April 2008

Targeting serum antibody for cancer diagnosis: a focus on colorectal cancer.

Expert Opin Ther Targets 2007 Feb;11(2):235-44

Tumor Vaccine Group, Center for Translational Medicine in Women's Health, University of Washington, 815 Mercer Street, Room 219, Seattle, WA, USA.

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http://dx.doi.org/10.1517/14728222.11.2.235 DOI Listing
February 2007

The tumor antigen repertoire identified in tumor-bearing neu transgenic mice predicts human tumor antigens.

Cancer Res 2006 Oct;66(19):9754-61

Tumor Vaccine Group, Center for Translational Medicine in Women's Health, University of Washington, Seattle, WA 98195, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-1083DOI Listing
October 2006

IL-2 immunotoxin therapy modulates tumor-associated regulatory T cells and leads to lasting immune-mediated rejection of breast cancers in neu-transgenic mice.

J Immunol 2006 Jul;177(1):84-91

Department of Immunology, Mayo Clinic College of Medicine, 342C Guggenheim, 200 First Street SW, Rochester, MN 55905, USA.

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http://dx.doi.org/10.4049/jimmunol.177.1.84DOI Listing
July 2006

De novo generation of CD4 T cells against viruses present in the host during immune reconstitution.

Blood 2005 Mar 12;105(6):2410-4. Epub 2004 Oct 12.

Fred Hutchinson Cancer Research Center and the University of Washington School of Medicine, Seattle, WA, USA.

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http://dx.doi.org/10.1182/blood-2004-01-0348DOI Listing
March 2005

Interleukin-7 improves reconstitution of antiviral CD4 T cells.

Clin Immunol 2005 Jan;114(1):30-41

Fred Hutchinson Cancer Research Center and University of Washington, Seattle, WA, USA.

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http://dx.doi.org/10.1016/j.clim.2004.08.008DOI Listing
January 2005

Inorganic lead activates the mitogen-activated protein kinase kinase-mitogen-activated protein kinase-p90(RSK) signaling pathway in human astrocytoma cells via a protein kinase C-dependent mechanism.

J Pharmacol Exp Ther 2002 Mar;300(3):818-23

Department of Environmental, University of Washington, Seattle, Washington 98105, USA.

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http://dx.doi.org/10.1124/jpet.300.3.818DOI Listing
March 2002