Haijian Wang

Haijian Wang

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Haijian Wang

Haijian Wang

Publications by authors named "Haijian Wang"

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Trans-acting nonsynonymous variant of FOXA1 predisposes to hepatocellular carcinoma through modulating FOXA1-ERα transcriptional program and may have undergone natural selection.

Carcinogenesis 2019 Aug 11. Epub 2019 Aug 11.

State Key Laboratory of Genetic Engineering and Collaborative Innovation Center for Genetics and Development, School of Life Sciences; Institutes of Biomedical Sciences, Shanghai Medical College, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1093/carcin/bgz136DOI Listing
August 2019

Artificial MicroRNA-Mediated Tgfbr2 and Pdgfrb Co-Silencing Ameliorates Carbon Tetrachloride-Induced Hepatic Fibrosis in Mice.

Hum Gene Ther 2019 Feb 13;30(2):179-196. Epub 2018 Nov 13.

1 The Fifth People's Hospital of Shanghai, State Key Laboratory of Genetic Engineering and Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Institutes of Biomedical Sciences of Shanghai Medical College, Fudan University, Shanghai, P.R. China.

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http://dx.doi.org/10.1089/hum.2018.047DOI Listing
February 2019

Genetic polymorphism of is associated with clinical outcomes of platinum-based chemotherapy in non-small-cell lung cancer patients through modulating microRNA-mediated regulation.

Oncotarget 2018 May 8;9(35):23860-23877. Epub 2018 May 8.

State Key Laboratory of Genetic Engineering and Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, China.

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http://dx.doi.org/10.18632/oncotarget.24794DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963629PMC
May 2018

Association of TERT Polymorphisms with Clinical Outcome of Non-Small Cell Lung Cancer Patients.

PLoS One 2015 28;10(5):e0129232. Epub 2015 May 28.

State Key Laboratory of Genetic Engineering and MOE Key Laboratory of Contemporary Anthropology, Institute of Genetics, School of Life Sciences, Fudan University, Shanghai, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0129232PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447454PMC
April 2016

Genetic Variants of the MDM2 Gene Are Predictive of Treatment-Related Toxicities and Overall Survival in Patients With Advanced NSCLC.

Clin Lung Cancer 2015 Sep 19;16(5):e37-53. Epub 2015 Feb 19.

State Key Laboratory of Genetic Engineering and MOE Key Laboratory of Contemporary Anthropology, Fudan University School of Life Sciences and Fudan Taizhou Institute of Health Sciences, Shanghai, China. Electronic address:

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http://dx.doi.org/10.1016/j.cllc.2015.02.001DOI Listing
September 2015

Histone H3K9 demethylase JMJD1A modulates hepatic stellate cells activation and liver fibrosis by epigenetically regulating peroxisome proliferator-activated receptor γ.

FASEB J 2015 May 21;29(5):1830-41. Epub 2015 Jan 21.

*State Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences; Institutes of Biomedical Sciences of Shanghai Medical College, Fudan University, Shanghai, China; Department of Chemistry, Fudan University, Shanghai, China; and State Key Laboratory of Proteomics, Beijing Proteome Research Center, Beijing Institute of Radiation Medicine, Beijing, China

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http://dx.doi.org/10.1096/fj.14-251751DOI Listing
May 2015

Pulmonary expression of CYP2A13 and ABCB1 is regulated by FOXA2, and their genetic interaction is associated with lung cancer.

FASEB J 2015 May 9;29(5):1986-98. Epub 2015 Feb 9.

*State Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences; Institutes of Biomedical Sciences of Shanghai Medical College, Fudan University, Shanghai, China; Department of Etiology and Carcinogenesis, Cancer Institute, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China; Department of Cardiothoracic Surgery, Changzheng Hospital of the Second Military Medical University, Shanghai, China; and State Key Laboratory of Proteomics, Beijing Institute of Radiation Medicine, Beijing, China

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http://dx.doi.org/10.1096/fj.14-264580DOI Listing
May 2015

Revisiting the role of MCL1 in tumorigenesis of solid cancer: gene expression correlates with antiproliferative phenotype in breast cancer cells and its functional regulatory variants are associated with reduced cancer susceptibility.

Tumour Biol 2014 Aug 23;35(8):8289-99. Epub 2014 May 23.

State Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, 138 Yixueyuan Rd., 200433, Shanghai, China.

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http://dx.doi.org/10.1007/s13277-014-2108-5DOI Listing
August 2014

Fumigant, contact, and repellent activities of essential oils against the darkling beetle, Alphitobius diaperinus.

J Insect Sci 2014 May 30;14:75. Epub 2014 May 30.

Sichuan Agricultural University, Biorational Pesticide Research Lab, 611130, Chengdu, China

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http://dx.doi.org/10.1093/jis/14.1.75DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207510PMC
May 2014

Association of CASP7 polymorphisms and survival of patients with non-small cell lung cancer with platinum-based chemotherapy treatment.

Chest 2012 Sep;142(3):680-689

State Key Laboratory of Genetic Engineering and MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences and Fudan Taizhou Institute of Health Sciences, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1378/chest.11-2522DOI Listing
September 2012

Matrix metalloproteinase-2 polymorphisms and clinical outcome of Chinese patients with nonsmall cell lung cancer treated with first-line, platinum-based chemotherapy.

Cancer 2012 Jul 9;118(14):3587-98. Epub 2011 Nov 9.

State Key Laboratory of Genetic Engineering and MOE Key Laboratory of Contemporary Anthropology, Institute of Genetics, School of Life Sciences, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1002/cncr.26669DOI Listing
July 2012

Functional variable number of tandem repeats variation in the promoter of proto-oncogene PTTG1IP is associated with risk of estrogen receptor-positive breast cancer.

Cancer Sci 2012 Jun 12;103(6):1121-8. Epub 2012 Apr 12.

State Key Laboratory of Genetic Engineering, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1111/j.1349-7006.2012.02266.xDOI Listing
June 2012

Functional regulatory variants of MCL1 contribute to enhanced promoter activity and reduced risk of lung cancer in nonsmokers: implications for context-dependent phenotype of an antiapoptotic and antiproliferative gene in solid tumor.

Cancer 2012 Apr 1;118(8):2085-95. Epub 2011 Sep 1.

State Key Laboratory of Genetic Engineering and MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai, People's Republic of China.

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http://dx.doi.org/10.1002/cncr.26502DOI Listing
April 2012

Regulation of female reproduction by p53 and its family members.

FASEB J 2011 Jul 14;25(7):2245-55. Epub 2011 Mar 14.

Cancer Institute of New Jersey, University of Medicine and Dentistry of New Jersey, New Brunswick, New Jersey, USA.

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http://dx.doi.org/10.1096/fj.10-180166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114525PMC
July 2011

The origins and evolution of the p53 family of genes.

Cold Spring Harb Perspect Biol 2010 Jun 16;2(6):a001198. Epub 2009 Dec 16.

Institute for Advanced Study, Princeton, NJ 08540, USA.

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http://cshperspectives.cshlp.org/lookup/doi/10.1101/cshpersp
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http://dx.doi.org/10.1101/cshperspect.a001198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869528PMC
June 2010

Fine-scale detection of population-specific linkage disequilibrium using haplotype entropy in the human genome.

BMC Genet 2010 Apr 23;11:27. Epub 2010 Apr 23.

The Simons Center for Systems Biology, Institute for Advanced Study, Princeton, New Jersey, USA.

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http://dx.doi.org/10.1186/1471-2156-11-27DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873552PMC
April 2010

Molecular population genetics of human CYP3A locus: signatures of positive selection and implications for evolutionary environmental medicine.

Environ Health Perspect 2009 Oct 18;117(10):1541-8. Epub 2009 Jun 18.

State Key Laboratory of Proteomics, Beijing Proteome Research Center, Beijing Institute of Radiation Medicine, Chinese National Human Genome Center at Beijing, Beijing, China.

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http://dx.doi.org/10.1289/ehp.0800528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790508PMC
October 2009

Association between polymorphisms in the GSTA4 gene and risk of lung cancer: a case-control study in a Southeastern Chinese population.

Mol Carcinog 2009 Mar;48(3):253-259

State Key Laboratory of Genetic Engineering and Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1002/mc.20478DOI Listing
March 2009

Genetic susceptibility of lung cancer associated with common variants in the 3' untranslated regions of the adenosine triphosphate-binding cassette B1 (ABCB1) and ABCC1 candidate transporter genes for carcinogen export.

Cancer 2009 Feb;115(3):595-607

State Key Laboratory of Genetic Engineering, Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1002/cncr.24042DOI Listing
February 2009

Association of the variable number of tandem repeats polymorphism in the promoter region of the SMYD3 gene with risk of esophageal squamous cell carcinoma in relation to tobacco smoking.

Cancer Sci 2008 Apr 21;99(4):787-91. Epub 2008 Feb 21.

MOE Key Laboratory of Contemporary Anthropology, State Key Laboratory of Genetic Engineering, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai 200433, China.

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http://dx.doi.org/10.1111/j.1349-7006.2008.00729.xDOI Listing
April 2008

Polymorphisms in hMLH1 and risk of early-onset lung cancer in a southeast Chinese population.

Lung Cancer 2008 Feb 17;59(2):164-70. Epub 2007 Sep 17.

State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Handan Road, Shanghai 200433, China.

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http://dx.doi.org/10.1016/j.lungcan.2007.08.003DOI Listing
February 2008

Comparative and evolutionary pharmacogenetics of ABCB1: complex signatures of positive selection on coding and regulatory regions.

Pharmacogenet Genomics 2007 Aug;17(8):667-78

MOE Key Laboratory of Contemporary Anthropology, Center for Evolutionary Biology, State Key Laboratory of Genetic Engineering, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai, PR China.

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http://dx.doi.org/10.1097/FPC.0b013e328165249fDOI Listing
August 2007

Beta-2 adrenergic receptor gene (ADRB2) polymorphism and risk for lung adenocarcinoma: a case-control study in a Chinese population.

Cancer Lett 2006 Aug 10;240(2):297-305. Epub 2005 Nov 10.

Laboratory of Systems Biology, Institutes of Biomedical Sciences, Fudan University, 138 Yixueyuan Rd, Shanghai 200032, People's Republic of China.

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http://dx.doi.org/10.1016/j.canlet.2005.09.018DOI Listing
August 2006

CYP2J2*7 single nucleotide polymorphism in a Chinese population.

Clin Chim Acta 2006 Mar 21;365(1-2):125-8. Epub 2005 Sep 21.

Laboratory of Systems Biology, Institutes of Biomedical Sciences, Fudan University, 138 Yixueyuan Rd., Shanghai 200032, PR China.

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http://dx.doi.org/10.1016/j.cca.2005.08.007DOI Listing
March 2006

The G-113A polymorphism in CYP1A2 affects the caffeine metabolic ratio in a Chinese population.

Clin Pharmacol Ther 2005 Sep;78(3):249-59

Department of Genomics and Proteomics, Beijing Institute of Radiation Medicine, Beijing, China.

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http://doi.wiley.com/10.1016/j.clpt.2005.05.012
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http://dx.doi.org/10.1016/j.clpt.2005.05.012DOI Listing
September 2005

Identification of genetic variants in base excision repair pathway and their associations with risk of esophageal squamous cell carcinoma.

Cancer Res 2004 Jun;64(12):4378-84

Laboratory of Systems Biology, Beijing Institute of Radiation Medicine, Beijing, People's Republic of China.

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http://dx.doi.org/10.1158/0008-5472.CAN-04-0372DOI Listing
June 2004

Substantial reduction in risk of lung adenocarcinoma associated with genetic polymorphism in CYP2A13, the most active cytochrome P450 for the metabolic activation of tobacco-specific carcinogen NNK.

Cancer Res 2003 Nov;63(22):8057-61

Laboratory of Systems Biology, Beijing Institute of Radiation Medicine, and Chinese National Human Genome Center at Beijing, Beijing 100850, China.

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November 2003

Histamine N-methyltransferase gene polymorphisms in Chinese and their relationship with enzyme activity in erythrocytes.

Pharmacogenetics 2003 Jul;13(7):389-97

Pharmacogenetics Research Institute, Institute of Clinical Pharmacology, Central South University, Changsha, PR China.

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http://dx.doi.org/10.1097/01.fpc.0000054099.48725.c1DOI Listing
July 2003

Multiplex single-nucleotide polymorphism genotyping by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

Anal Biochem 2003 Mar;314(1):54-62

Department of Genomics and Proteomics, Beijing Institute of Radiation Medicine, Beijing, 100850, PR China.

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http://dx.doi.org/10.1016/s0003-2697(02)00641-3DOI Listing
March 2003