Hai-Ling Margaret Cheng

Hai-Ling Margaret Cheng

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Hai-Ling Margaret Cheng

Hai-Ling Margaret Cheng

Publications by authors named "Hai-Ling Margaret Cheng"

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MRI method for labeling and imaging decellularized extracellular matrix scaffolds for tissue engineering.

Magn Reson Med 2019 Nov 14. Epub 2019 Nov 14.

Institute of Biomaterials & Biomedical Engineering, University of Toronto, Canada.

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http://dx.doi.org/10.1002/mrm.28072DOI Listing
November 2019

Heart failure with preserved ejection fraction: the missing pieces in diagnostic imaging.

Heart Fail Rev 2019 Jul 31. Epub 2019 Jul 31.

Institute of Biomaterials & Biomedical Engineering, University of Toronto, 164 College Street, RS407, Toronto, Ontario, M5S 3G9, Canada.

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http://dx.doi.org/10.1007/s10741-019-09836-8DOI Listing
July 2019

An Efficient Contrast Agent for Labeling and Tracking Human Embryonic Stem Cells on MRI.

Contrast Media Mol Imaging 2019 16;2019:3475786. Epub 2019 Jun 16.

Institute of Biomaterials & Biomedical Engineering, University of Toronto, 164 College Street, RS407, Toronto, ON, Canada M5S 3G9.

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http://dx.doi.org/10.1155/2019/3475786DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6604499PMC
June 2019

Assessment of microvascular dysfunction in acute limb ischemia-reperfusion injury.

J Magn Reson Imaging 2019 04 9;49(4):1174-1185. Epub 2018 Oct 9.

Ted Rogers Centre for Heart Research, Translational Biology & Engineering Program, Toronto, Canada.

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http://doi.wiley.com/10.1002/jmri.26308
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http://dx.doi.org/10.1002/jmri.26308DOI Listing
April 2019

One-Step Labeling of Collagen Hydrogels with Polydopamine and Manganese Porphyrin for Non-Invasive Scaffold Tracking on Magnetic Resonance Imaging.

Macromol Biosci 2019 04 15;19(4):e1800330. Epub 2019 Jan 15.

Institute of Biomaterials & Biomedical Engineering, The Edward S. Rogers Sr. Department of Electrical & Computer Engineering, Ted Rogers Centre for Heart Research, Translational Biology & Engineering Program, University of Toronto, 164 College Street, RS407, Toronto, ON, M5S 3G9, Canada.

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http://doi.wiley.com/10.1002/mabi.201800330
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http://dx.doi.org/10.1002/mabi.201800330DOI Listing
April 2019

Synthesis of degradable-polar-hydrophobic-ionic co-polymeric microspheres by membrane emulsion photopolymerization: In vitro and in vivo studies.

Acta Biomater 2019 04 7;89:279-288. Epub 2019 Mar 7.

Translational Biology and Engineering Program, Ted Rogers Centre for Heart Research, Institute of Biomaterials and Biomedical Engineering, University of Toronto, Ontario M5R 1M1, Canada; Faculty of Dentistry, University of Toronto, Ontario M5G 1G6, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.actbio.2019.03.014DOI Listing
April 2019

Establishment of a lung metastatic breast tumor xenograft model in nude rats.

PLoS One 2014 16;9(5):e97950. Epub 2014 May 16.

The Research Institute and Diagnostic Imaging, Hospital for Sick Children, Toronto, Ontario, Canada; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada; The Institute of Biomaterials & Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0097950PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4024026PMC
August 2015

Manganese-enhanced MRI of minimally gadolinium-enhancing breast tumors.

J Magn Reson Imaging 2015 Mar 4;41(3):806-13. Epub 2014 Mar 4.

The Research Institute (Physiology & Experimental Medicine) and Diagnostic Imaging, Hospital for Sick Children, Toronto, Canada; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Canada.

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http://doi.wiley.com/10.1002/jmri.24608
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http://dx.doi.org/10.1002/jmri.24608DOI Listing
March 2015

Gadolinium-free extracellular MR contrast agent for tumor imaging.

J Magn Reson Imaging 2015 Feb 8;41(2):397-403. Epub 2014 Jan 8.

The Research Institute and Diagnostic Imaging, Hospital for Sick Children, Toronto, Canada; Department of Medical Biophysics, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1002/jmri.24561DOI Listing
February 2015

Gadolinium-free T1 contrast agents for MRI: tunable pharmacokinetics of a new class of manganese porphyrins.

J Magn Reson Imaging 2014 Dec 8;40(6):1474-80. Epub 2013 Nov 8.

Physiology and Experimental Medicine and Diagnostic Imaging, Hospital for Sick Children, Toronto, Canada; Department of Medical Biophysics, University of Toronto, Toronto, Canada; Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Canada; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Canada.

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http://doi.wiley.com/10.1002/jmri.24483
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http://dx.doi.org/10.1002/jmri.24483DOI Listing
December 2014

3D myocardial T1 mapping at 3T using variable flip angle method: pilot study.

Magn Reson Med 2014 Feb;71(2):823-9

Université de Lorraine, IADI, UMR S 947, Nancy, France; INSERM, IADI, U947, Nancy, France.

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http://dx.doi.org/10.1002/mrm.24688DOI Listing
February 2014

Binding of a dimeric manganese porphyrin to serum albumin: towards a gadolinium-free blood-pool T1 MRI contrast agent.

J Biol Inorg Chem 2014 Feb 10;19(2):229-35. Epub 2014 Jan 10.

Department of Physical and Environmental Sciences, University of Toronto Scarborough, 1265 Military Trail, Toronto, ON, M1C 1A4, Canada.

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http://link.springer.com/10.1007/s00775-013-1073-6
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http://dx.doi.org/10.1007/s00775-013-1073-6DOI Listing
February 2014

Complementary strategies for developing Gd-free high-field T₁ MRI contrast agents based on Mn(III) porphyrins.

J Med Chem 2014 Jan 7;57(2):516-20. Epub 2014 Jan 7.

Department of Chemistry, University of Toronto , Toronto, Ontario, M5S 3H6, Canada.

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http://dx.doi.org/10.1021/jm401124bDOI Listing
January 2014

Ultrashort echo time for improved positive-contrast manganese-enhanced MRI of cancer.

PLoS One 2013 4;8(3):e58617. Epub 2013 Mar 4.

Department of Medical Biophysics, University of Toronto, Toronto, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0058617PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3587583PMC
September 2013

Effect of hyperoxia and hypercapnia on tissue oxygen and perfusion response in the normal liver and kidney.

PLoS One 2012 6;7(7):e40485. Epub 2012 Jul 6.

Physiology & Experimental Medicine, The Hospital for Sick Children Research Institute, Toronto, Ontario, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0040485PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391313PMC
April 2013

Practical medical applications of quantitative MR relaxometry.

J Magn Reson Imaging 2012 Oct;36(4):805-24

Physiology and Experimental Medicine, Research Institute, The Hospital for Sick Children, Toronto, ON, Canada.

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http://dx.doi.org/10.1002/jmri.23718DOI Listing
October 2012

Concurrent dual contrast for cellular magnetic resonance imaging using gadolinium oxide and iron oxide nanoparticles.

Int J Mol Imaging 2012 2;2012:230942. Epub 2012 Aug 2.

Physiology and Experimental Medicine, The Research Institute, The Hospital for Sick Children, Toronto, ON, Canada M5G 1X8.

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http://dx.doi.org/10.1155/2012/230942DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419425PMC
August 2012

Human aortic endothelial cell labeling with positive contrast gadolinium oxide nanoparticles for cellular magnetic resonance imaging at 7 Tesla.

Mol Imaging 2012 Apr;11(2):166-75

Department of Physiology and Experimental Medicine, The Research Institute, The Hospital for Sick Children, Toronto, ON, Canada.

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April 2012

Monitoring tissue development in acellular matrix-based regeneration for bladder tissue engineering: multiexponential diffusion and T2* for improved specificity.

NMR Biomed 2012 Mar 4;25(3):418-26. Epub 2011 Feb 4.

Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1002/nbm.1617DOI Listing
March 2012

Normal tissue quantitative T1 and T2* MRI relaxation time responses to hypercapnic and hyperoxic gases.

Acad Radiol 2011 Sep 24;18(9):1159-67. Epub 2011 Jun 24.

The Research Institute and Diagnostic Imaging, The Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.acra.2011.04.016DOI Listing
September 2011

Quantification of renal perfusion: comparison of arterial spin labeling and dynamic contrast-enhanced MRI.

J Magn Reson Imaging 2011 Sep 14;34(3):608-15. Epub 2011 Jul 14.

Research Institute, Diagnostic Imaging, Hospital for Sick Children, Toronto, Canada.

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http://dx.doi.org/10.1002/jmri.22660DOI Listing
September 2011

Quantitative MRI assessment of VX2 tumour oxygenation changes in response to hyperoxia and hypercapnia.

Phys Med Biol 2011 Mar 1;56(5):1225-42. Epub 2011 Feb 1.

The Research Institute and Diagnostic Imaging, The Hospital for Sick Children, Toronto, Canada.

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http://dx.doi.org/10.1088/0031-9155/56/5/001DOI Listing
March 2011

A general dual-bolus approach for quantitative DCE-MRI.

Magn Reson Imaging 2011 Feb 3;29(2):160-6. Epub 2010 Dec 3.

The Research Institute and Diagnostic Imaging, The Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.mri.2010.08.009DOI Listing
February 2011

Temporal resolution and SNR requirements for accurate DCE-MRI data analysis using the AATH model.

Magn Reson Med 2010 Dec 16;64(6):1772-80. Epub 2010 Aug 16.

The Research Institute and Diagnostic Imaging, The Hospital for Sick Children, Toronto, Canada.

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http://dx.doi.org/10.1002/mrm.22573DOI Listing
December 2010

The acellular matrix (ACM) for bladder tissue engineering: A quantitative magnetic resonance imaging study.

Magn Reson Med 2010 Aug;64(2):341-8

Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/mrm.22404DOI Listing
August 2010

A technique for rapid single-echo spin-echo T2 mapping.

Magn Reson Med 2010 Aug;64(2):536-45

Medical Imaging, University Health Network, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/mrm.22454DOI Listing
August 2010

Impact of motion on T1 mapping acquired with inversion recovery fast spin echo and rapid spoiled gradient recalled-echo pulse sequences for delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) in volunteers.

J Magn Reson Imaging 2010 Aug;32(2):394-8

Department of Medical Imaging, Mount Sinai Hospital and University Health Network, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1002/jmri.22249DOI Listing
August 2010

Improved correlation to quantitative DCE-MRI pharmacokinetic parameters using a modified initial area under the uptake curve (mIAUC) approach.

J Magn Reson Imaging 2009 Oct;30(4):864-72

The Research Institute & Diagnostic Imaging, The Hospital for Sick Children and Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/jmri.21916DOI Listing
October 2009

Delayed gadolinium-enhanced MR imaging of articular cartilage: three-dimensional T1 mapping with variable flip angles and B1 correction.

Radiology 2009 Sep 31;252(3):865-73. Epub 2009 Jul 31.

Department of Medical Imaging, Mount Sinai Hospital and the University Health Network, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1148/radiol.2531081115DOI Listing
September 2009

Accurate liver T2 measurement of iron overload: a simulations investigation and in vivo study.

J Magn Reson Imaging 2009 Aug;30(2):313-20

The Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/jmri.21835DOI Listing
August 2009

Investigation and optimization of parameter accuracy in dynamic contrast-enhanced MRI.

J Magn Reson Imaging 2008 Sep;28(3):736-43

Research Institute, Department of Diagnostic Imaging, Hospital for Sick Children, Department of Medical Imaging, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/jmri.21489DOI Listing
September 2008

MRI and contrast-enhanced ultrasound monitoring of prostate microwave focal thermal therapy: an in vivo canine study.

J Magn Reson Imaging 2008 Jul;28(1):136-43

Department of Diagnostic Imaging, Hospital for Sick Children Research Institute, 555 University Avenue, Toronto, Ontario, Canada.

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http://doi.wiley.com/10.1002/jmri.21415
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http://dx.doi.org/10.1002/jmri.21415DOI Listing
July 2008

T1 measurement of flowing blood and arterial input function determination for quantitative 3D T1-weighted DCE-MRI.

J Magn Reson Imaging 2007 May;25(5):1073-8

Department of Diagnostic Imaging, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/jmri.20898DOI Listing
May 2007

Dynamic contrast-enhanced MRI in oncology drug development.

Curr Clin Pharmacol 2007 May;2(2):111-22

Department of Diagnostic Imaging, The Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.2174/157488407780598180DOI Listing
May 2007

Quantifying angiogenesis in VEGF-enhanced tissue-engineered bladder constructs by dynamic contrast-enhanced MRI using contrast agents of different molecular weights.

J Magn Reson Imaging 2007 Jan;25(1):137-45

Department of Diagnostic Imaging, The Hospital for Sick Children, Toronto, Canada.

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http://dx.doi.org/10.1002/jmri.20787DOI Listing
January 2007

Dynamic contrast-enhanced MRI to quantify VEGF-enhanced tissue-engineered bladder graft neovascularization: pilot study.

J Biomed Mater Res A 2006 May;77(2):390-5

The Hospital for Sick Children, Division of Urology, University of Toronto, Toronto, Ontario, Canada.

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http://doi.wiley.com/10.1002/jbm.a.30648
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http://dx.doi.org/10.1002/jbm.a.30648DOI Listing
May 2006

Rapid high-resolution T(1) mapping by variable flip angles: accurate and precise measurements in the presence of radiofrequency field inhomogeneity.

Magn Reson Med 2006 Mar;55(3):566-74

Department of Diagnostic Imaging & The Research Institute, The Hospital for Sick Children, Toronto, Canada.

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http://doi.wiley.com/10.1002/mrm.20791
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http://dx.doi.org/10.1002/mrm.20791DOI Listing
March 2006

Dynamic Gd-DTPA enhanced MRI as a surrogate marker of angiogenesis in tissue-engineered bladder constructs: a feasibility study in rabbits.

J Magn Reson Imaging 2005 Apr;21(4):415-23

Department of Diagnostic Imaging, The Hospital for Sick Children, Toronto, Canada.

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http://dx.doi.org/10.1002/jmri.20278DOI Listing
April 2005

Usefulness of contrast kinetics for predicting and monitoring tissue changes in muscle following thermal therapy in long survival studies.

J Magn Reson Imaging 2004 Mar;19(3):329-41

Department of Medical Biophysics, University of Toronto, Sunnybrook and Women's College Health Sciences Center, Toronto, Canada.

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http://dx.doi.org/10.1002/jmri.20014DOI Listing
March 2004

Prediction of subtle thermal histopathological change using a novel analysis of Gd-DTPA kinetics.

J Magn Reson Imaging 2003 Nov;18(5):585-98

Department of Medical Biophysics, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1002/jmri.10388DOI Listing
November 2003

Tissue thermal conductivity by magnetic resonance thermometry and focused ultrasound heating.

J Magn Reson Imaging 2002 Nov;16(5):598-609

Department of Medical Biophysics, University of Toronto, Sunnybrook and Women's College Health Sciences Center, Toronto, Canada.

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http://dx.doi.org/10.1002/jmri.10199DOI Listing
November 2002