Hai-Bin Ruan

Hai-Bin Ruan

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Hai-Bin Ruan

Hai-Bin Ruan

Publications by authors named "Hai-Bin Ruan"

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31Publications

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Cell Metabolism Control Through O-GlcNAcylation of STAT5: A Full or Empty Fuel Tank Makes a Big Difference for Cancer Cell Growth and Survival.

Int J Mol Sci 2019 Feb 27;20(5). Epub 2019 Feb 27.

Institute of Animal Breeding and Genetics, University of Veterinary Medicine Vienna, 1210 Vienna, Austria.

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http://dx.doi.org/10.3390/ijms20051028DOI Listing
February 2019

Transcriptional regulation of -GlcNAc homeostasis is disrupted in pancreatic cancer.

J Biol Chem 2018 09 23;293(36):13989-14000. Epub 2018 Jul 23.

From the Program in Integrative Cell Signaling and Neurobiology of Metabolism and

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http://dx.doi.org/10.1074/jbc.RA118.004709DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130940PMC
September 2018

Inhibition of PPARγ, adipogenesis and insulin sensitivity by MAGED1.

J Endocrinol 2018 Aug 18. Epub 2018 Aug 18.

H Ruan, Integrative Biology and Physiology, University of Minnesota Twin Cities, Minneapolis, 55455, United States

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https://joe.bioscientifica.com/view/journals/joe/aop/joe-18-
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http://dx.doi.org/10.1530/JOE-18-0349DOI Listing
August 2018

Ketone bodies as epigenetic modifiers.

Curr Opin Clin Nutr Metab Care 2018 07;21(4):260-266

Division of Molecular Medicine, Department of Medicine.

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http://dx.doi.org/10.1097/MCO.0000000000000475DOI Listing
July 2018

Gut microbiota profiling in Han Chinese with type 1 diabetes.

Diabetes Res Clin Pract 2018 Jul 5;141:256-263. Epub 2018 May 5.

Department of Endocrinology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China. Electronic address:

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http://dx.doi.org/10.1016/j.diabres.2018.04.032DOI Listing
July 2018

Brown adipose tissue activation in a rat model of Parkinson's disease.

Am J Physiol Endocrinol Metab 2017 12 29;313(6):E731-E736. Epub 2017 Aug 29.

Department of Human Anatomy, Histology, and Embryology, School of Basic Medical Sciences, Capital Medical University, Beijing, China;

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http://dx.doi.org/10.1152/ajpendo.00049.2017DOI Listing
December 2017

Calcium-dependent O-GlcNAc signaling drives liver autophagy in adaptation to starvation.

Genes Dev 2017 08 13;31(16):1655-1665. Epub 2017 Sep 13.

Program in Integrative Cell Signaling and Neurobiology of Metabolism, Department of Comparative Medicine, Yale University School of Medicine, New Haven, Connecticut 06520, USA.

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http://dx.doi.org/10.1101/gad.305441.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647936PMC
August 2017

Proteomic analysis reveals diverse proline hydroxylation-mediated oxygen-sensing cellular pathways in cancer cells.

Oncotarget 2016 Nov;7(48):79154-79169

Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota at Twin Cities, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.18632/oncotarget.12632DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346705PMC
November 2016

Neuronal Control of Adaptive Thermogenesis.

Front Endocrinol (Lausanne) 2015 25;6:149. Epub 2015 Sep 25.

Program in Integrative Cell Signaling and Neurobiology of Metabolism, Yale University School of Medicine , New Haven, CT , USA ; Section of Comparative Medicine, Yale University School of Medicine , New Haven, CT , USA.

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http://dx.doi.org/10.3389/fendo.2015.00149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585244PMC
October 2015

Hepatic acetyl CoA links adipose tissue inflammation to hepatic insulin resistance and type 2 diabetes.

Cell 2015 Feb 5;160(4):745-758. Epub 2015 Feb 5.

Howard Hughes Medical Institute, Yale University, New Haven, CT 06519, USA; Department of Internal Medicine, Yale University, New Haven, CT 06520, USA; Department of Cellular and Molecular Physiology, Yale University, New Haven, CT 06520, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2015.01.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498261PMC
February 2015

O-GlcNAc transferase enables AgRP neurons to suppress browning of white fat.

Cell 2014 Oct;159(2):306-17

Program in Integrative Cell Signaling and Neurobiology of Metabolism, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA; Section of Comparative Medicine, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA; Department of Cellular and Molecular Physiology, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2014.09.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509746PMC
October 2014

The stem cell factor/Kit signalling pathway regulates mitochondrial function and energy expenditure.

Nat Commun 2014 Jul 7;5:4282. Epub 2014 Jul 7.

MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing University, Nanjing, Jiangsu 210061, China.

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http://dx.doi.org/10.1038/ncomms5282DOI Listing
July 2014

Cyclin D1-Cdk4 controls glucose metabolism independently of cell cycle progression.

Nature 2014 Jun 25;510(7506):547-51. Epub 2014 May 25.

1] Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA [2] Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/nature13267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076706PMC
June 2014

Mutation in the first Ig-like domain of Kit leads to JAK2 activation and myeloproliferation in mice.

Am J Pathol 2014 Jan 7;184(1):122-32. Epub 2013 Nov 7.

MOE Key Lab of Model Animal for Disease Study, Model Animal Research Center, Nanjing University, Nanjing, China. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2013.09.019DOI Listing
January 2014

Regulation of protein degradation by O-GlcNAcylation: crosstalk with ubiquitination.

Mol Cell Proteomics 2013 Dec 3;12(12):3489-97. Epub 2013 Jul 3.

Program in Integrative Cell Signaling and Neurobiology of Metabolism and Section of Comparative Medicine, Department of Cellular & Molecular Physiology, Yale University School of Medicine, 333 Cedar Street, New Haven, Connecticut 06520;

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http://dx.doi.org/10.1074/mcp.R113.029751DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861702PMC
December 2013

Cracking the O-GlcNAc code in metabolism.

Trends Endocrinol Metab 2013 Jun 4;24(6):301-9. Epub 2013 May 4.

Program in Integrative Cell Signaling and Neurobiology of Metabolism, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06519, USA.

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http://dx.doi.org/10.1016/j.tem.2013.02.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783028PMC
June 2013

O-GlcNAc signaling entrains the circadian clock by inhibiting BMAL1/CLOCK ubiquitination.

Cell Metab 2013 Feb;17(2):303-10

Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT 06520, USA.

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http://dx.doi.org/10.1016/j.cmet.2012.12.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647362PMC
February 2013

O-GlcNAc transferase/host cell factor C1 complex regulates gluconeogenesis by modulating PGC-1α stability.

Cell Metab 2012 Aug;16(2):226-37

Program in Integrative Cell Signaling and Neurobiology of Metabolism, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06519, USA.

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http://dx.doi.org/10.1016/j.cmet.2012.07.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480732PMC
August 2012

O-GlcNAc transferase is involved in glucocorticoid receptor-mediated transrepression.

J Biol Chem 2012 Apr 27;287(16):12904-12. Epub 2012 Feb 27.

Department of Cellular and Molecular Physiology, Section of Comparative Medicine and Program in Integrative Cell Signaling and Neurobiology of Metabolism, Yale University School of Medicine, New Haven, Connecticut 06520, USA.

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http://dx.doi.org/10.1074/jbc.M111.303792DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339970PMC
April 2012

Protein phosphatase 2A catalytic subunit α (PP2Acα) maintains survival of committed erythroid cells in fetal liver erythropoiesis through the STAT5 pathway.

Am J Pathol 2011 May;178(5):2333-43

Key Laboratory of Model Animal for Disease Study of Ministry of Education, Model Animal Research Center, Nanjing University, Nanjing, China.

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http://dx.doi.org/10.1016/j.ajpath.2011.01.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081176PMC
May 2011

Identification of a novel nonsense mutation on the Pax3 gene in ENU-derived white belly spotting mice and its genetic interaction with c-Kit.

Pigment Cell Melanoma Res 2010 Apr 22;23(2):252-62. Epub 2010 Jan 22.

Key Laboratory of Molecular Developmental Biology, Institute of Genetics & Developmental Biology, Chinese Academy of Sciences, Beijing, China.

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http://dx.doi.org/10.1111/j.1755-148X.2010.00677.xDOI Listing
April 2010

Identification of a novel point mutation of mouse proto-oncogene c-kit through N-ethyl-N-nitrosourea mutagenesis.

Genetics 2005 Feb;169(2):819-31

Model Animal Research Center, State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210089, People's Republic of China.

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http://dx.doi.org/10.1534/genetics.104.027177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1449128PMC
February 2005