Publications by authors named "H T Wang"

99,526 Publications

An ESIPT-based fluorescent probe with fast-response for detection of hydrogen sulfide in mitochondria.

Spectrochim Acta A Mol Biomol Spectrosc 2021 Sep 10;265:120390. Epub 2021 Sep 10.

Department of Chemistry, Xinzhou Teachers University, Xinzhou, Shanxi 034000, China.

Excited-state intramolecular proton transfer (ESIPT) has recently received considerable attention due to its dual fluorescent changes and large Stokes shift. Hydrogen sulfide (HS) is a gas signal molecule that plays important roles in modulating the functions of different systems. Herein, by modifying 2-(2́-hydroxyphenyl) benzothiazole (HBT) scaffold, a novel near-infrared mitochondria-targeted fluorescent probe HBTP-HS has been rationally designed based on excited-state intramolecular proton transfer (ESIPT) effect. The nucleophilic addition reaction of the HS with probe HBTP-HS caused the break of the conjugated skeleton, resulting the shifting of maximum emission peak from 658 nm to 470 nm. HBTP-HS showed fast-response response time, good selectivity and a large Stokes shift (188 nm) toward HS. Most importantly, inspired by the inherent advantages of the probe, HBTP-HS was successfully employed to monitor mitochondrial HS in HepG2 cells.
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http://dx.doi.org/10.1016/j.saa.2021.120390DOI Listing
September 2021

Facile fabrication of PS/CuS/Ag sandwich structure as SERS substrate for ultra-sensitive detection.

Spectrochim Acta A Mol Biomol Spectrosc 2021 Sep 10;265:120370. Epub 2021 Sep 10.

Key Laboratory of Preparation and Applications of Environmental Friendly Materials (Jilin Normal University), Ministry of Education, Changchun 130103, China. Electronic address:

In this work, a serials of PS(polystyrene)/CuS/Ag sandwich substrates were successfully constructed using the magnetic sputtering method by adjusting the Ag sputtering time (0 min, 2 min, 4 min, 6 min, 8 min and 10 min) and used as the surface-enhanced Raman scattering (SERS) substrates. When the Ag sputtering time was 6 min, the strongest SERS signal was observed. The optimized SERS substrate has strong SERS activity on 4-mercaptobenzoic acid (4-MBA), the minimum detection limit was 10 M and the enhancement factor was as high as 4.7 × 10. In addition, the SERS signals were highly reproducible with small standard deviation. The SERS enhancement mechanism of the PS/CuS/Ag system was attributed to the synergistic effect of the chemical mechanism and the electromagnetic enhancement mechanism. This strategy has find a new way for manufacturing SERS activity sensor with high sensitivity and reproducibility.
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http://dx.doi.org/10.1016/j.saa.2021.120370DOI Listing
September 2021

Dual recognition strategy for selective fluorescent detection of dopamine and antioxidants based on graphite carbon nitride in human blood serum.

Spectrochim Acta A Mol Biomol Spectrosc 2021 Sep 10;265:120385. Epub 2021 Sep 10.

Hubei Collaborative Innovation Center for Rare Metal Chemistry, Hubei Key Laboratory of Pollutant Analysis & Reuse Technology, College of Chemistry and Chemical Engineering, Hubei Normal University, Huangshi 435002, China. Electronic address:

In this work, a strong blue-emitting fluorescent biosensor based on graphite carbon nitride nanoparticles (GCNNs) (E = 340 nm and E = 435 nm) was synthesized by a facile one-step hydrothermal method. With the aid of hydrogen peroxide and horseradish peroxidase, pyrocatechol structure of dopamine (DA) was oxidized to o-quinone structure of polydopamine (PDA) by hydroxyl radical. PDA was able to rapidly and significantly quench fluorescence of GCNNs. In the meanwhile, oxidative self-polymerization from DA to PDA would be blocked by antioxidants, such as glutathione (GSH) and ascorbic acid (AA). Thus, the fluorescence of [email protected] sensor would be recovered owing to the decrease of o-quinone. Based on above-mentioned dual recognition strategy of "turn-off" and "turn off-on", a fast, simple and ultrasensitive method was developed to measure DA and antioxidants. Under the optimal experimental conditions, the detection limits of DA, GSH and AA were 0.064 μmol L, 0.11 μmol L and 0.16 μmol L with relative standard deviations of 1.7%, 9.3% and 8.0%, respectively. As one of metal-free quantum dots, our GCNNs-based sensors were also successfully applied to the determination of DA as well as GSH and AA in human serum. The recoveries for the spiked samples were in the range of 93.8%-109% and 95.0%-110% of DA and antioxidants, which shows great promise to clinicalapplication.
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http://dx.doi.org/10.1016/j.saa.2021.120385DOI Listing
September 2021

Integrated effects of microbial decomposing inoculant on greenhouse gas emissions, grain yield and economic profit from paddy fields under different water regimes.

Sci Total Environ 2021 Sep 11;805:150295. Epub 2021 Sep 11.

MOA Key Laboratory of Crop Ecophysiology and Farming System in the Middle Reaches of the Yangtze River/College of Plant Science & Technology, Huazhong Agricultural University, Wuhan 430070, PR China; Hubei Collaborative Innovation Center for Grain Industry, Yangtze University, Jingzhou 434023, Hubei, PR China. Electronic address:

Few studies have comprehensively evaluated the impacts of microbial decomposing inoculants on greenhouse gas emissions and economic profit from paddy fields under different water regimes. Here, this study evaluated the effects of microbial decomposing inoculant treatments (straw returning without or with microbial decomposing inoculants (S and SMD)) on rice yield, CH and NO emissions, economic profit and net ecosystem economic profit (NEEP) from paddy fields under different water regimes (continuous flooding (CF) and alternate wetting and drying irrigation (AWD)) in central China with a two-year field experiment. Compared with S treatment, SMD treatment significantly increased the rice yield and crop water productivity by 6.6-7.2% and 5.6-7.9%, respectively. AWD treatment significantly enhanced the crop water productivity by 56.9-73.7% while did not affect rice yield relative to CF treatment. Regardless of water regimes, SMD treatment did not affect NO emissions, but significantly increased CH emissions by 13.8-39.6% relative to S treatment, resulting in a remarkable enhancement of global warming potential by 13.5-32.5%. Compared with S treatment, SMD treatment improved the economic profit and NEEP. By contrast, AWD treatment significantly increased NO emissions by 19.1-64.8% compared with CF treatment, but significantly reduced CH emissions by 35.3-79.1%. Accordingly, AWD treatment significantly decreased the global warming potential by 33.4-73.9% compared with CF treatment. In addition, AWD treatment resulted in 39.9-96.4% higher economic profit and 48.0-124.4% higher NEEP relative to CF treatment. In summary, AWD treatment is a sustainable water regime that can maintain rice yield, mitigate global warming potential, and increase economic income. However, regardless of water regimes, SMD treatment led to higher rice yield and economic profit, as well as higher global warming potential than S treatment, suggesting that other appropriate treatments of crop straw are needed to mitigate CH emissions while improving economic profit for rice sustainable production.
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http://dx.doi.org/10.1016/j.scitotenv.2021.150295DOI Listing
September 2021

Design of a metamaterial film with excellent conformability and adhesion for bandage substrates.

J Mech Behav Biomed Mater 2021 Sep 10;124:104799. Epub 2021 Sep 10.

School of Mechanical Engineering, Beijing Institute of Technology, Beijing, 100089, PR China. Electronic address:

Developing films with excellent conformability and adhesion has become a research hotspot in many fields, such as medical bandages. The conventional method for enhancing films conformability and adhesion is to make the films thinner or modify the material of the films, which usually compromises the function of the films. In this paper, a novel metamaterial film was proposed to cover the skin area of a human elbow during the rotation of elbow. This structure is composed of unit cells with rectangular perforations, whose Poisson's ratio (PR) is determined by the length of the perforation. With finite element analysis (FEA), relations among the stretch strain, Poisson's ratio and length of the perforation of unit cell was obtained. Then, the proposed film was generated by mapping unit cells with different PR to the target skin surface. With the same deformation behavior as the elbow skin, conformability and adhesion of the generated film can be guaranteed during the entire rotation process of the elbow, which has been verified by both FEA and experimental tests. Theoretically, by changing the arrangement of different PR unit cells, the proposed method can be applied to design films for other complex surface on human body. It also provides a new way to introduce materials with better biocompatibility but poor mechanical properties as bandage substrates. As a possible application, a prototype of smart bandage was developed by installing a high-resolution temperature sensor on the proposed film, which can monitor the inflammation of the wounded skin in real time.
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http://dx.doi.org/10.1016/j.jmbbm.2021.104799DOI Listing
September 2021
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