Publications by authors named "Gwenaelle Gravis"

100Publications

Deterioration of Sexual Health in Cancer Survivors Five Years after Diagnosis: Data from the French National Prospective VICAN Survey.

Cancers (Basel) 2020 Nov 20;12(11). Epub 2020 Nov 20.

APHM, INSERM, IRD, SESSTIM, Sciences Economiques & Sociales de la Santé & Traitement de l'Information Médicale, Equipe CANBIOS Labellisée Ligue Contre le Cancer, Hop Timone, BioSTIC, Biostatistique et Technologies de l'Information et de la Communication, Aix Marseille Univ, 13005 Marseille, France.

View Article and Find Full Text PDF
November 2020

A combined biological and clinical rationale for evaluating metastasis directed therapy in the management of oligometastatic prostate cancer.

Radiother Oncol 2020 Nov 25;152:80-88. Epub 2020 Aug 25.

Jewish General Hospital, Montreal, Canada; McGill University, Montreal, Canada. Electronic address:

View Article and Find Full Text PDF
November 2020

Metastatic hormone sensitive prostate cancer: local treatment strategies.

World J Urol 2020 Jun 25. Epub 2020 Jun 25.

Department of Medical Oncology, Institut Paoli-Calmettes Cancer Centre, Marseille, France.

View Article and Find Full Text PDF
June 2020

A simple and rapid liquid chromatography-mass spectrometry method to assay cabozantinib in plasma: Application to therapeutic drug monitoring in patients with renal cell carcinoma.

J Chromatogr B Analyt Technol Biomed Life Sci 2020 Feb 7;1138:121968. Epub 2020 Jan 7.

SMARTc Unit, Centre de Recherche en Cancérologie de Marseille, Inserm U1068, Aix Marseille Université, Marseille, France; Laboratoire de Pharmacocinétique et Toxicologie, La Timone University Hospital of Marseille, Marseille, France. Electronic address:

View Article and Find Full Text PDF
February 2020

Systemic treatment for metastatic prostate cancer.

Authors:
Gwenaelle Gravis

Asian J Urol 2019 Apr 11;6(2):162-168. Epub 2019 Feb 11.

Centre de Recherche en Cancerologie de Marseille (CRCM), Institut Paoli-Calmettes, Aix-Marseille University, Marseille, France.

View Article and Find Full Text PDF
April 2019

The Biology of Oligometastatic Prostate Cancer: A Different Beast than Polymetastatic Prostate Cancer.

Eur Urol Focus 2019 03 4;5(2):117-118. Epub 2018 Dec 4.

Jewish General Hospital, Montreal, Canada. Electronic address:

View Article and Find Full Text PDF
March 2019

Long-term efficacy of crizotinib in a metastatic papillary renal carcinoma with MET amplification: a case report and literature review.

BMC Cancer 2018 Nov 22;18(1):1159. Epub 2018 Nov 22.

Department of Medical Oncology, Institut Paoli-Calmettes, 232 Bd de Sainte-Marguerite, 13009, Marseille, France.

View Article and Find Full Text PDF
November 2018

Sunitinib Alone or after Nephrectomy in Metastatic Renal-Cell Carcinoma.

N Engl J Med 2018 Aug 3;379(5):417-427. Epub 2018 Jun 3.

From the Departments of Urology (A.M., M.-O.T.) and Medical Oncology (S.O.), Hôpital Européen Georges-Pompidou, Assistance Publique-Hôpitaux de Paris (AP-HP), Université Paris-Descartes, and Paris Descartes Necker-Cochin Clinical Research Unit, AP-HP (S.C.), Paris, the Department of Medical Oncology, Bordeaux University Hospital (A.R.), the Department of Medical Oncology, Hôpital Saint André, Centre Hospitalier Universitaire (CHU) de Bordeaux (M.G.-G.), and the Department of Urology, CHU de Bordeaux and Université de Bordeaux (J.-C.B.), Bordeaux, Biometrics Unit, Cancer Institute of Montpellier, University of Montpellier, Montpellier (S.T.), the Department of Urology, CHU Rangueil (J.-B.B.), and the Department of Medical Oncology, Institut Universitaire du Cancer Toulouse-Oncopole (C.C.), Toulouse, the Department of Urology, University of Rennes (K.B.), and the Department of Medical Oncology, Centre Eugene Marquis (B.L.), Rennes, the Department of Medical Oncology, Institut de Cancerologie de Lorraine, Vandoeuvre lès Nancy (L. Geoffrois), the Department of Medical Oncology, CHU Besançon, Oncologie, and Université de Franche-Comte, INSERM Unité Mixte de Recherche (UMR) 1098, Structure Fédérative de Recherche Ingénierie et Biologie Cellulaire et Tissulaire, Besançon (A.T.-V.), the Department of Urology, CHU François Mitterrand, Dijon (L.C.), the Department of Urology, CHU Strasbourg, Translational Medicine Federation Strasbourg, Strasbourg (H.L.), the Department of Urology, Gabriel Montpied Hospital, and Clermont Auvergne University, Clermont-Ferrand (L. Guy), the Department of Medical Oncology, Centre de Recherche en Cancerologie de Marseille, INSERM UMR 1068, Centre National de la Recherche Scientifique UMR 7258 and Institut Paoli-Calmettes (G.G.), and the Department of Urology, Hôpital la Conception (E.L.), Aix Marseille Université, Marseille, the Department of Medical Oncology, Institut de Cancerologie de l'Ouest, Nantes (F.R.), the Department of Medical Oncology, CHU Bretonneau, and the Department of Medicine, Université François Rabelais, Tours (C.L.), the Department of Urology, Mont de Marsan General Hospital, Mont de Marsan (J.-J.P.), the Departments of Medical Oncology (C.T.) and Urology (T.L.), Hôpital Foch, Suresnes, the Department of Urology, Imagerie Adaptative Diagnostique et Interventionnelle INSERM Unité 1254, CHU de Nancy, Brabois (J.H.), the Department of Medical Oncology, Institut Gustave Roussy and Université Paris-Saclay, Villejuif (L.A., B.E.), and Université Versailles, St.-Quentin-en-Yvelines (T.L.) - all in France; the Department of Urology, Haukeland University Hospital (C.B.), and the Department of Clinical Medicine, University of Bergen (C.B.), Bergen, Norway; and the Department of Urology, Royal Free Hospital, London (M.A.).

View Article and Find Full Text PDF
August 2018

[The role and use of Patient Reported Outcomes in the management of cancer patients].

Bull Cancer 2018 Jun;105(6):603-609

Centre de recherche en cancérologie de Marseille (CRCM), Inserm, U1068, 13009 Marseille, France; CNRS, UMR7258, 13009 Marseille, France; Institut Paoli-Calmettes, 13009 Marseille, France; Aix-Marseille université, UM 105, 13284 Marseille, France.

View Article and Find Full Text PDF
June 2018

Long-term complete remission with Ipilimumab in metastatic castrate-resistant prostate cancer: case report of two patients.

J Immunother Cancer 2017 18;5:31. Epub 2017 Apr 18.

Institut Gustave Roussy, University of Paris-Sud, Department of Cancer Medicine, 114 Rue Edouard Vaillant, 94800 Villejuif, France.

View Article and Find Full Text PDF
June 2018

Randomized, Double-Blind, Phase III Trial of Ipilimumab Versus Placebo in Asymptomatic or Minimally Symptomatic Patients With Metastatic Chemotherapy-Naive Castration-Resistant Prostate Cancer.

J Clin Oncol 2017 Jan 31;35(1):40-47. Epub 2016 Oct 31.

Tomasz M. Beer, Oregon Health and Science University, Portland, OR; Eugene D. Kwon, Mayo Clinic, Rochester, MN; Charles G. Drake, Johns Hopkins University, Baltimore, MD; Karim Fizazi, University of Paris-Sud, Villejuif; Gwenaelle Gravis, Institut Paoli-Calmettes, Marseille, France; Christopher Logothetis, University of Texas MD Anderson Cancer Center, Houston, TX; Vinod Ganju, Monash University, Melbourne, Victoria; Siobhan S. Ng, St John of God Hospital, Subiaco, Western Australia; Francis X. Parnis, Adelaide Cancer Centre, Adelaide, South Australia, Australia; Jonathan Polikoff, Southern California Permanente Medical Group, San Marcos, CA; Fred Saad, Centre Hospitalier de l'Université de Montréal, Montreal, Quebec, Canada; Piotr Humanski, Niepubliczny Zaklad Opieki Zdrowotnej Specjalista, Kutno, Poland; Josep M. Piulats, Institut Català d'Oncologia, Barcelona; Javier Puente, Hospital Clínico San Carlos, Madrid, Spain; Pablo Gonzalez Mella, Instituto Oncologico, Viña del Mar; Pablo Gonzalez Mella, Fundación Arturo Lopez Pérez, Santiago, Chile; Dirk Jaeger, University Hospital, Heidelberg, Germany; Fabio A. Franke, Hospital de Caridade de Ijuí, Ijuí, Brazil; Roman Carvajal, Hospital Regional Valentin Gomez Farias, Zapopan, Mexico; Lisa Sengeløv, Herlev Hospital, Herlev, Denmark; M. Brent McHenry, Bristol-Myers Squibb, Wallingford, CT; Arvind Varma, DOCS Inc, New York, NY; Alfonsus J. van den Eertwegh, VU University Medical Center, Amsterdam; and Winald Gerritsen, Radboud University, Nijmegen, the Netherlands.

View Article and Find Full Text PDF
January 2017

Inherent and Tumor-Driven Immune Tolerance in the Prostate Microenvironment Impairs Natural Killer Cell Antitumor Activity.

Cancer Res 2016 04 5;76(8):2153-65. Epub 2016 Apr 5.

Centre de Recherche en Cancérologie de Marseille, INSERM U1068/CNRS U7258, Marseille, France. Institut Paoli-Calmettes, Marseille, France. Aix Marseille Université, Marseille, France.

View Article and Find Full Text PDF
April 2016

Radiation therapy following targeted therapy in oligometastatic renal cell carcinoma.

Mol Clin Oncol 2015 Nov 30;3(6):1248-1250. Epub 2015 Jul 30.

Department of Radiotherapy, Paoli-Calmettes Institute, 13009 Marseille, France.

View Article and Find Full Text PDF
November 2015

Trebananib (AMG 386) in Combination With Sunitinib in Patients With Metastatic Renal Cell Cancer: An Open-Label, Multicenter, Phase II Study.

J Clin Oncol 2015 Oct 24;33(30):3431-8. Epub 2015 Aug 24.

Michael B. Atkins, Georgetown University, Washington, DC; Gwenaelle Gravis, Institut Paoli Calmettes, Marseille; Alain Ravaud, Centre Hospitalier Universitaire de Bordeaux, Hôpital Saint André, Bordeaux, France; Kazimierz Drosik, Regional Cancer Center, Opole; Tomasz Demkow, Maria Skłodowska-Curie Memorial Cancer Center, Warsaw; Piotr Tomczak, University of Medical Sciences, Poznan, Poland; Shirley S. Wong, Western Hospital, Footscray, Victoria, Australia; M. Dror Michaelson, Massachusetts General Hospital; Toni K. Choueiri, Dana-Farber Cancer Institute, Boston, MA; and Benjamin Wu, Lynn Navale, and Douglas Warner, Amgen, Thousand Oaks, CA.

View Article and Find Full Text PDF
October 2015

Sarcoidosis Occurring After Solid Cancer: A Nonfortuitous Association: Report of 12 Cases and Review of the Literature.

Medicine (Baltimore) 2015 Jul;94(28):e928

From the Department of Internal Medicine, CHU Timone, Assistance Publique-Hôpitaux de Marseille, Marseille (AG, ME, EB, VV, J-RH, NS); Department of Internal Medicine, CHU Conception, Assistance Publique-Hôpitaux de Marseille, Aix-Marseille Université, Marseille (KM, RJ); Department of Hematology, Paoli Calmette Institute, Marseille (DC, TA-S, FB, RB); Department of Oncology, Paoli Calmette Institute, Marseille (GG, AG, MG); Department of Internal Medicine, Croix-Rousse Hospital, Lyon (PS); Department of Pathology, Paoli Calmette Institute, Marseille (BC); Department of Internal Medicine, Alpes du Sud Hospital, Gap (FG-B, TW); and Department of Oncology, Desgenettes Hospital, Lyon (MP), France.

View Article and Find Full Text PDF
July 2015

[Metastatic hormone-sensitive prostate cancer].

Bull Cancer 2015 Jan 8;102(1):57-64. Epub 2015 Jan 8.

Institut Paoli-Calmettes, service de chirurgie urologique, 13009 Marseille, France.

View Article and Find Full Text PDF
January 2015

[Axitinib in metastatic renal carcinomas: update of knowledge about side effects].

Bull Cancer 2014 Oct;101(10):976-88

Institut Gustave-Roussy, Département d'oncologie médicale, 39, rue Camille-Desmoulins, 94805 Villejuif cedex, France.

View Article and Find Full Text PDF
October 2014

Comparison of image-guided targeted biopsies versus systematic randomized biopsies in the detection of prostate cancer: a systematic literature review of well-designed studies.

World J Urol 2014 Aug 12;32(4):847-58. Epub 2014 Jun 12.

Department of Urology, Institut Paoli-Calmettes Cancer Centre, 232, Boulevard Ste. Marguerite, BP 156, 13273, Marseille, France.

View Article and Find Full Text PDF
August 2014

Reassessment of scoring systems and prognostic factors for metastatic spinal cord compression.

Spine J 2015 May 9;15(5):944-50. Epub 2013 Oct 9.

Department of Medical Oncology, Institut Paoli Calmettes, 232 bd de sainte Marguerite, 13009 Marseille, France. Electronic address:

View Article and Find Full Text PDF
May 2015

Major response with sorafenib in advanced renal cell carcinoma after 14 years of follow-up.

World J Surg Oncol 2013 Sep 27;11:243. Epub 2013 Sep 27.

Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.

View Article and Find Full Text PDF
September 2013

[Pharmaco and diet based prostate cancer prevention].

Bull Cancer 2013 May;100(5):497-507

Institut Paoli-Calmettes (IPC), département d'anticipation et de suivi des cancers (Cancer Control Department), 232, boulevard Sainte-Marguerite, 13009 Marseille, France.

View Article and Find Full Text PDF
May 2013

Development of an ELISA detecting Tumor Protein 53-Induced Nuclear Protein 1 in serum of prostate cancer patients.

Results Immunol 2013 28;3:51-6. Epub 2013 May 28.

Inserm, U1068, CRCM, Marseille F-13009, France ; Institut Paoli-Calmettes, Marseille F-13009, France ; Aix-Marseille Université, Marseille F-13284, France ; CNRS, UMR7258, CRCM, Marseille F-13009, France.

View Article and Find Full Text PDF
March 2014

The use of estramustine phosphate in the modern management of advanced prostate cancer.

BJU Int 2011 Dec 14;108(11):1782-6. Epub 2011 Jul 14.

Department of Urology, Hôpital Bichat-Claude Bernard, Université Paris VII Denis-Diderot, France.

View Article and Find Full Text PDF
December 2011

Identification of the prostate cancer index lesion by real-time elastography: considerations for focal therapy of prostate cancer.

World J Urol 2011 Oct 26;29(5):589-94. Epub 2011 May 26.

Department of Urology, Institut Paoli-Calmettes, 232, Boulevard Ste. Marguerite/B.P.: 156, 13273 Marseille, France.

View Article and Find Full Text PDF
October 2011

[Management of side-effects of targeted therapies in renal cancer: endocrine side-effects and metabolic disorders].

Bull Cancer 2011 ;98(3 Suppl):S47-59

CHU Cochin, urologie, 27, rue du Faubourg-Saint-Jacques, 75679 Paris Cedex 14, France.

View Article and Find Full Text PDF
March 2015

Three cases of severe ulcerative esophagitis induced by SUTENT®.

J Gastrointest Cancer 2012 Mar;43(1):128-30

Department of Oncological Medico-Surgical Explorations, Institut Paoli-Calmettes, Marseille, France.

View Article and Find Full Text PDF
March 2012

Randomized study of intravenous versus subcutaneous interleukin-2, and IFNalpha in patients with good prognosis metastatic renal cancer.

Clin Cancer Res 2008 Sep;14(18):5907-12

Université de Lyon, Centre Léon Bérard, Medical Oncology Department, Institut National de la Sante et de la Recherche Medicale U.590 and Biostatistics Unit, Centre Léon Bérard, Lyon Cedex 08, France.

View Article and Find Full Text PDF
September 2008

[Prostate cancer and chemotherapy].

Bull Cancer 2007 Jul;94(7 Suppl):F21-8

Institut Paoli-Calmettes, Marseille.

View Article and Find Full Text PDF
July 2007

Medullary thyroid cancer treated by capecitabine.

Anticancer Drugs 2007 Aug;18(7):831-4

Department of Medical Oncology, Institut Paoli Calmettes, 232 Boulevard Sainte Marguerite, 13009 Marseille, France.

View Article and Find Full Text PDF
August 2007

FGFR1 and WT1 are markers of human prostate cancer progression.

BMC Cancer 2006 Nov 30;6:272. Epub 2006 Nov 30.

Centre de Recherche en Cancérologie de Marseille, Département d'Oncologie Moléculaire, UMR599 Inserm et Institut Paoli-Calmettes, Marseille, France.

View Article and Find Full Text PDF
November 2006

Inflammatory cytokines and acute graft-versus-host disease after reduced-intensity conditioning allogeneic stem cell transplantation.

Blood 2005 Dec 1;106(13):4407-11. Epub 2005 Sep 1.

Département d'Oncologie Médicale, Laboratoire d'Immunologie des Tumeurs, Unité de Transplantation et de Thérapie Cellulaire (UTTC), Marseille, France.

View Article and Find Full Text PDF
December 2005