Publications by authors named "Guy Van Camp"

100Publications

On the pathophysiology of DFNA9: Effect of pathogenic variants in the COCH gene on inner ear functioning in human and transgenic mice.

Hear Res 2020 Dec 30;401:108162. Epub 2020 Dec 30.

Department of Translational Neurosciences, Faculty of Medicine and Health Sciences, University of Antwerp, Belgium; Department of Otorhinolaryngology and Head & Neck surgery, Antwerp University Hospital, Belgium.

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December 2020

GSDME and its role in cancer: From behind the scenes to the front of the stage.

Int J Cancer 2020 Nov 13. Epub 2020 Nov 13.

Center of Medical Genetics, University of Antwerp and Antwerp University Hospital, Antwerp, Belgium.

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November 2020

Autosomal Dominantly Inherited GREB1L Variants in Individuals with Profound Sensorineural Hearing Impairment.

Genes (Basel) 2020 06 23;11(6). Epub 2020 Jun 23.

Center for Statistical Genetics, Sergievsky Center, Taub Institute for Alzheimer's Disease and the Aging Brain, and the Department of Neurology, Columbia University Medical Center, New York, NY 10032, USA.

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June 2020

Disturbing effect of lockdown for COVID-19 on the incidence of infective endocarditis: a word of caution.

Clin Res Cardiol 2020 Dec 10;109(12):1573-1576. Epub 2020 Jun 10.

Heart Center OLV Aalst, Moorselbaan 164, 9300, Aalst, Belgium.

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December 2020

DNA Methylation Distinguishes Two Subtypes of Pancreatic Neuroendocrine Neoplasms with a Different Prognosis.

Cancers (Basel) 2020 Jun 4;12(6). Epub 2020 Jun 4.

Center for Oncological Research, University of Antwerp and Antwerp University Hospital, 2610 Antwerp, Belgium.

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June 2020

Resistance to targeted treatment of gastroenteropancreatic neuroendocrine tumors

Endocr Relat Cancer 2019 03 1;26(3):R109-R130. Epub 2019 Mar 1.

Center of Medical Genetics, University of Antwerp and Antwerp University Hospital, Antwerp, Belgium.

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March 2019

The Gene Has Potential as a Pan-Cancer Biomarker, While Discriminating between Different Tumor Types.

Cancers (Basel) 2019 Nov 18;11(11). Epub 2019 Nov 18.

Centre of Medical Genetics, University of Antwerp and Antwerp University Hospital, Prins Boudewijnlaan 43, 2650 Edegem, Belgium.

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November 2019

Clinical applications of (epi)genetics in gastroenteropancreatic neuroendocrine neoplasms: Moving towards liquid biopsies.

Rev Endocr Metab Disord 2019 09;20(3):333-351

Center for Oncological Research (CORE), University of Antwerp and Antwerp University Hospital, Universiteitsplein 1, 2610, Wilrijk, Belgium.

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September 2019

Methylation analysis of Gasdermin E shows great promise as a biomarker for colorectal cancer.

Cancer Med 2019 05 16;8(5):2133-2145. Epub 2019 Apr 16.

Centre of Medical Genetics, University of Antwerp and Antwerp University Hospital, Edegem, Belgium.

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May 2019

Insufficient evidence for a role of SERPINF1 in otosclerosis.

Mol Genet Genomics 2019 Aug 9;294(4):1001-1006. Epub 2019 Apr 9.

Center of Medical Genetics, University of Antwerp and Antwerp University Hospital, Universiteitsplein 1, Wilrijk, 2610, Antwerp, Belgium.

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August 2019

A systematic review of hearing and vestibular function in carriers of the Pro51Ser mutation in the COCH gene.

Eur Arch Otorhinolaryngol 2019 May 26;276(5):1251-1262. Epub 2019 Feb 26.

Department of ENT Head and Neck Surgery, Antwerp University Hospital, Antwerp, Belgium.

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May 2019

Giant pseudoaneurysm of the left ventricle.

Int J Cardiovasc Imaging 2019 06 23;35(6):1161-1162. Epub 2019 Feb 23.

Cardiovascular Center Aalst, OLV Clinic, Aalst, Belgium.

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June 2019

Tumor-specific genetic variants can be detected in circulating cell-free DNA of malignant pleural mesothelioma patients.

Lung Cancer 2018 10 21;124:19-22. Epub 2018 Jul 21.

Center of Medical Genetics, University of Antwerp and Antwerp University Hospital, Prins Boudewijnlaan 43, 2650 Antwerp, Belgium; Center for Oncological Research, University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium.

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October 2018

Molecular analysis of an asbestos-exposed Belgian family with a high prevalence of mesothelioma.

Fam Cancer 2018 10;17(4):569-576

Center of Medical Genetics, University of Antwerp and Antwerp University Hospital, Prins Boudewijnlaan 43, 2650, Antwerp, Belgium.

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October 2018

Large-scale analysis of methylation reveals its potential as biomarker for breast cancer.

Clin Epigenetics 2018 11;10:51. Epub 2018 Apr 11.

Center of Medical Genetics, University of Antwerp and Antwerp University Hospital, Prins Boudewijnlaan 43/6, BE-2650 Edegem, Antwerp Belgium.

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May 2019

Mutation and Methylation Analysis of Circulating Tumor DNA Can Be Used for Follow-up of Metastatic Colorectal Cancer Patients.

Clin Colorectal Cancer 2018 06 22;17(2):e369-e379. Epub 2018 Feb 22.

Center for Oncological Research (CORE), University of Antwerp, Antwerp, Belgium; Department of Oncology, Antwerp University Hospital, Antwerp, Belgium. Electronic address:

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June 2018

Hemangioma of the mitral valve as a rare, incidental finding in an adult female.

Acta Cardiol 2019 Apr 20;74(2):180-181. Epub 2018 Mar 20.

a Department of Cardiology , OLV Clinic Aalst , Aalst , Belgium.

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April 2019

Bi-allelic inactivating variants in the COCH gene cause autosomal recessive prelingual hearing impairment.

Eur J Hum Genet 2018 04 15;26(4):587-591. Epub 2018 Feb 15.

Center of Medical Genetics, University of Antwerp and Antwerp University Hospital, Antwerp, Belgium.

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April 2018

The predictive value of primary tumor location in patients with metastatic colorectal cancer: A systematic review.

Crit Rev Oncol Hematol 2018 Jan 7;121:1-10. Epub 2017 Nov 7.

Center of Oncological Research (CORE), University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium; Center of Medical Genetics, University of Antwerp and Antwerp University Hospital, Prins Boudewijnlaan 43/6, 2650 Edegem, Belgium. Electronic address:

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January 2018

Unique autosomal recessive variant of palmoplantar keratoderma associated with hearing loss not caused by known mutations.

An Bras Dermatol 2017 ;92(5 Suppl 1):154-158

Department of Medical Genetics, University of Antwerp, Universiteitsplein - Antwerp, Belgium.

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March 2018

pyAmpli: an amplicon-based variant filter pipeline for targeted resequencing data.

BMC Bioinformatics 2017 Dec 14;18(1):554. Epub 2017 Dec 14.

Center of Medical Genetics, University of Antwerp, Prins Boudewijnlaan 43, 2650, Antwerp, Belgium.

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December 2017

Summary of 2017 ESC guidelines on valvular heart disease, peripheral artery disease, STEMI and on dual antiplatelet therapy.

Acta Cardiol 2018 Oct 11;73(5):419-425. Epub 2017 Dec 11.

Department of Cardiology, Antwerp University Hospital , Edegem , Belgium.

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October 2018

The Aortic Valve replAcemenT versus conservative treatment in Asymptomatic seveRe aortic stenosis (AVATAR trial): A protocol update.

Am Heart J 2018 01 14;195:153-154. Epub 2017 Oct 14.

University Clinical Center of Serbia, Belgrade, Serbia; Belgrade Medical School, University of Belgrade, Serbia.

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January 2018

A new perspective on the genetics of keratoconus: why have we not been more successful?

Ophthalmic Genet 2018 04 7;39(2):158-174. Epub 2017 Nov 7.

a Department of Biomedical Sciences , Center of Medical Genetics, University of Antwerp & Antwerp University Hospital , Antwerp , Belgium.

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April 2018

Molecular diagnostics for hereditary hearing loss in children.

Expert Rev Mol Diagn 2017 08 19;17(8):751-760. Epub 2017 Jun 19.

a Center of Medical Genetics , University of Antwerp & Antwerp University Hospital , Antwerp , Belgium.

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August 2017

DFNA5 promoter methylation a marker for breast tumorigenesis.

Oncotarget 2017 May;8(19):31948-31958

Center of Medical Genetics, University of Antwerp and Antwerp University Hospital, Edegem B-2650, Belgium.

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May 2017

A Pilot Genome-Wide Association Study Identifies Potential Metabolic Pathways Involved in Tinnitus.

Front Neurosci 2017 2;11:71. Epub 2017 Mar 2.

Center for Medical Genetics, Antwerp University Hospital and University of AntwerpAntwerp, Belgium; StatUa Center for Statistics, University of AntwerpAntwerp, Belgium.

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March 2017

Ca-binding protein 2 inhibits Ca-channel inactivation in mouse inner hair cells.

Proc Natl Acad Sci U S A 2017 02 9;114(9):E1717-E1726. Epub 2017 Feb 9.

Institute for Auditory Neuroscience and InnerEarLab, University Medical Center Goettingen, 37099 Goettingen, Germany;

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February 2017

Congenital hearing loss.

Nat Rev Dis Primers 2017 01 12;3:16094. Epub 2017 Jan 12.

Department of Otorhinolaryngology, Head and Neck Surgery, Antwerp University Hospital, University of Antwerp, Antwerp, Belgium.

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January 2017

A novel missense mutation in the C2C domain of otoferlin causes profound hearing impairment in an Omani family with auditory neuropathy.

Saudi Med J 2016 Oct;37(10):1068-75

Department of Biochemistry, College of Medicine & Health Sciences, Sultan Qaboos University, Al-Khoud, Oman. E-mail.

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October 2016

The FAS-670 AA genotype is associated with high proviral load in peruvian HAM/TSP patients.

J Med Virol 2017 04 14;89(4):726-731. Epub 2016 Sep 14.

Molecular Epidemiology Laboratory, Institute of Tropical Medicine Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru.

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April 2017

Response: Asymptomatic severe aortic stenosis: Cardiopulmonary exercise testing in "the world of AVATAR".

Am Heart J 2016 08 25;178:e3-4. Epub 2016 Jun 25.

Belgrade Medical School, Belgrade, Serbia; University Clinical Centre of Serbia, 11000 Belgrade, Serbia.

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August 2016

The Genetic Landscape of Malignant Pleural Mesothelioma: Results from Massively Parallel Sequencing.

J Thorac Oncol 2016 10 6;11(10):1615-26. Epub 2016 Jun 6.

Center of Medical Genetics, University of Antwerp and Antwerp University Hospital, Antwerp, Belgium; Center for Oncological Research, University of Antwerp, Antwerp, Belgium.

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October 2016

Dyspnoea in a 36-year-old woman.

Heart 2016 06;102(12):e4

Cardiovascular Center Aalst, OLV Hospital, Aalst, Belgium.

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June 2016

Withaferin A induces heme oxygenase (HO-1) expression in endothelial cells via activation of the Keap1/Nrf2 pathway.

Biochem Pharmacol 2016 06 1;109:48-61. Epub 2016 Apr 1.

Laboratory of Eukaryotic Gene Expression and Signal Transduction (LEGEST), Department of Biochemistry and Microbiology, Ghent University, Proeftuinstraat 86, Gent, Belgium; Laboratory of Protein Science, Proteomics and Epigenetic Signaling (PPES), Department of Biomedical Sciences, University of Antwerp, Campus Drie Eiken, Universiteitsplein 1, Wilrijk, Belgium.

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June 2016

Whole-Genome Saliva and Blood DNA Methylation Profiling in Individuals with a Respiratory Allergy.

PLoS One 2016 21;11(3):e0151109. Epub 2016 Mar 21.

Environmental Risk and Health unit, Flemish Institute for Technological Research (VITO), Mol, Belgium.

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August 2016

Targeting of vascular cell adhesion molecule-1 by 18F-labelled nanobodies for PET/CT imaging of inflamed atherosclerotic plaques.

Eur Heart J Cardiovasc Imaging 2016 Sep 22;17(9):1001-8. Epub 2016 Jan 22.

In Vivo Cellular and Molecular Imaging (ICMI), Faculty of Medicine and Pharmacy, Vrije Universiteit Brussel (VUB), Laarbeeklaan 103, Brussels B-1090, Belgium.

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September 2016

Role of DFNA5 in hearing loss and cancer - a comment on Rakusic et al.

Onco Targets Ther 2015 15;8:2613-5. Epub 2015 Sep 15.

Center of Medical Genetics (CMG), Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.

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October 2015

Prognostic and Predictive Value of RAS Gene Mutations in Colorectal Cancer: Moving Beyond KRAS Exon 2.

Drugs 2015 Oct;75(15):1739-56

Center for Oncological Research Antwerp, University of Antwerp, Campus Drie Eiken, Universiteitsplein 1, Wilrijk, 2610, Antwerp, Belgium.

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October 2015

Next generation exome sequencing of pancreatic neuroendocrine tumor cell lines BON-1 and QGP-1 reveals different lineages.

Cancer Genet 2015 Oct 4;208(10):523. Epub 2015 Aug 4.

Department of Oncology, University of Antwerp, Antwerp, Belgium; Center of Medical Genetics, University of Antwerp, Antwerp, Belgium.

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October 2015

The deafness gene DFNA5 induces programmed cell death through mitochondria and MAPK-related pathways.

Front Cell Neurosci 2015 16;9:231. Epub 2015 Jul 16.

Department of Biomedical Sciences, Center of Medical Genetics, University of Antwerp Antwerp, Belgium.

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August 2015

A Frame-Shift Mutation in CAV1 Is Associated with a Severe Neonatal Progeroid and Lipodystrophy Syndrome.

PLoS One 2015 15;10(7):e0131797. Epub 2015 Jul 15.

Center for Rare Childhood Disorders, Translational Genomics Research Institute, Phoenix, AZ, United States of America; Neurogenomics Division, Translational Genomics Research Institute, Phoenix, AZ, United States of America.

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April 2016

Whole-exome characterization of pancreatic neuroendocrine tumor cell lines BON-1 and QGP-1.

J Mol Endocrinol 2015 Apr 22;54(2):137-47. Epub 2015 Jan 22.

Department of OncologyUniversity of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Antwerp, BelgiumSection of EndocrinologyDepartment of Internal Medicine, Erasmus Medical Center, Dr. Molenwaterplein 50, 3015GE Rotterdam, The NetherlandsCenter of Medical GeneticsDepartment of PathologyUniversity of Antwerp and Antwerp University Hospital, Universiteitsplein 1, 2610 Wilrijk, Antwerp, Belgium Department of OncologyUniversity of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Antwerp, BelgiumSection of EndocrinologyDepartment of Internal Medicine, Erasmus Medical Center, Dr. Molenwaterplein 50, 3015GE Rotterdam, The NetherlandsCenter of Medical GeneticsDepartment of PathologyUniversity of Antwerp and Antwerp University Hospital, Universiteitsplein 1, 2610 Wilrijk, Antwerp, Belgium.

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April 2015

Expression profiling of migrated and invaded breast cancer cells predicts early metastatic relapse and reveals Krüppel-like factor 9 as a potential suppressor of invasive growth in breast cancer.

Oncoscience 2014 18;1(1):69-81. Epub 2013 Jan 18.

Center for Oncological Research (CORE), University of Antwerp, Universiteitsplein 1, B-2610 Antwerp, Belgium ; Laboratory of Pathology, Antwerp University Hospital, Wilrijkstraat 10, B-2650 Edegem (Antwerp), Belgium.

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January 2015

Potentiometric detection in UPLC as an easy alternative to determine cocaine in biological samples.

Biomed Chromatogr 2015 Jul 16;29(7):1124-9. Epub 2014 Dec 16.

University of Antwerp, Department of Chemistry, Groenenborgerlaan 171, B-2020, Antwerp, Belgium.

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July 2015

Ectopic microRNA-150-5p transcription sensitizes glucocorticoid therapy response in MM1S multiple myeloma cells but fails to overcome hormone therapy resistance in MM1R cells.

PLoS One 2014 4;9(12):e113842. Epub 2014 Dec 4.

Laboratory of Protein Chemistry, Proteomics and Epigenetic Signalling (PPES), Department of Biomedical Sciences, University of Antwerp (UA), Antwerp, Belgium; Laboratory of Eukaryotic Gene Expression and Signal Transduction (LEGEST), Department of Physiology, Ghent University, Ghent, Belgium.

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July 2015

Concentration-related response potentiometric titrations to study the interaction of small molecules with large biomolecules.

Anal Chem 2014 Dec 25;86(24):12243-9. Epub 2014 Nov 25.

AXES Research Group and ‡Chromatographic Organic Trace Analysis, Department of Chemistry, University of Antwerp , Groenenborgerlaan 171, 2020 Antwerp, Belgium.

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December 2014

Overcoming cetuximab resistance in HNSCC: the role of AURKB and DUSP proteins.

Cancer Lett 2014 Nov 2;354(2):365-77. Epub 2014 Sep 2.

Center for Oncological Research (CORE) Antwerp, Laboratory of Cancer Research and Clinical Oncology, University of Antwerp, Universiteitsplein1, Wilrijk, Belgium.

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November 2014

Echocardiographic integrated backscatter for the differentiation between aortic valve calcification and valvular myxoid degeneration in rats.

Eur Heart J Cardiovasc Imaging 2014 Sep 30;15(9):1042-7. Epub 2014 Apr 30.

Department of Cardiology, Centrum Voor Hart-en Vaatziekten (CHVZ), UZ Brussel, Laarbeeklaan 101, 1090 Jette, Belgium In Vivo Cellular and Molecular Imaging Laboratory (ICMI), Faculty of Medicine and Pharmacy, Vrije Universiteit Brussel (VUB), Jette, Belgium.

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September 2014

Focal sclerosis of semicircular canals with severe DFNA9 hearing impairment caused by a P51S COCH-mutation: is there a link?

Otol Neurotol 2014 Jul;35(6):1077-86

*Department of Otorhinolaryngology, Campus Virga Jesse, †Department of Radiology, Jessa Hospital, Hasselt; ‡Department of Biomedical Sciences, Medical Genetics Centre, University of Antwerp, Antwerp; and §The Eargroup, Antwerp-Deurne, Belgium.

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July 2014

Gender differences in the management and outcome of atrial fibrillation complicating acute heart failure.

J Card Fail 2014 Jun 17;20(6):431-7. Epub 2014 Mar 17.

Department of Cardiology, AZ Maria-Middelares Hospital, Ghent, Belgium; Department of Internal Medicine Ghent University, Ghent, Belgium.

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June 2014

Genetic association analysis in a clinically and histologically confirmed otosclerosis population confirms association with the TGFB1 gene but suggests an association of the RELN gene with a clinically indistinguishable otosclerosis-like phenotype.

Otol Neurotol 2014 Jul;35(6):1058-64

*University of Antwerp, Department of Medical Genetics, Antwerp, Belgium; †Bajcsy-Zsilinszky Hospital, ENT Department, Budapest; and ‡University of Debrecen, Medical and Health Science Center, Department of Otolaryngology and Head and Neck Surgery, Debrecen, Hungary.

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July 2014