Publications by authors named "Guy Pratt"

100Publications

Bortezomib, Melphalan, Dexamethasone: A New Standard of Care for AL Amyloidosis?

Authors:
Guy Pratt

J Clin Oncol 2020 Aug 4:JCO2001904. Epub 2020 Aug 4.

University Hospitals Birmingham, National Health Service Foundation Trust, Birmingham, United Kingdom.

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http://dx.doi.org/10.1200/JCO.20.01904DOI Listing
August 2020

Post-transplant Monoclonal Gammopathy of Renal Significance: A Case Series.

Transplant Proc 2020 Apr 3;52(3):857-864. Epub 2020 Mar 3.

Department of Renal Medicine, University Hospitals Birmingham, Birmingham, United Kingdom.

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http://dx.doi.org/10.1016/j.transproceed.2019.12.040DOI Listing
April 2020

Levofloxacin prophylaxis in patients with myeloma - Authors' reply.

Lancet Oncol 2020 02;21(2):e69

Warwick Clinical Trials Unit, University of Warwick, Coventry, UK.

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http://dx.doi.org/10.1016/S1470-2045(20)30020-6DOI Listing
February 2020

Testing and management for monoclonal gammopathy of uncertain significance and myeloma patients presenting with osteoporosis and fragility fractures.

Rheumatology (Oxford) 2019 07;58(7):1142-1153

Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1093/rheumatology/kez127DOI Listing
July 2019

Correspondence on: A rare complication of bone marrow aspiration and trephine biopsy: Staphylococcus aureus osteomyelitis and septicaemia - response to Eades & Bapat.

Br J Haematol 2019 07 24;186(2):384. Epub 2019 Apr 24.

Department of Microbiology, University Hospital Birmingham NHS Foundation Trust, Birmingham, UK.

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http://dx.doi.org/10.1111/bjh.15930DOI Listing
July 2019

A rare complication of bone marrow aspiration and trephine biopsy: Staphylococcus aureus osteomyelitis and septicaemia.

Br J Haematol 2019 01 8;184(1). Epub 2018 Nov 8.

University Hospital Birmingham NHS Foundation Trust, Birmingham, UK.

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http://doi.wiley.com/10.1111/bjh.15630
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http://dx.doi.org/10.1111/bjh.15630DOI Listing
January 2019

National survey of imaging practice for suspected or confirmed plasma cell malignancies.

Br J Radiol 2018 Dec 1;91(1092):20180462. Epub 2018 Nov 1.

1 Cancer Imaging, School of Biomedical Engineering and Imaging Sciences, King's College London , London , UK.

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http://dx.doi.org/10.1259/bjr.20180462DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319860PMC
December 2018

Guidelines for the use of imaging in the management of patients with myeloma.

Br J Haematol 2017 08 5;178(3):380-393. Epub 2017 Jul 5.

Department of Haematology, University Hospital Birmingham NHS Foundation Trust, Birmingham, UK.

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http://doi.wiley.com/10.1111/bjh.14827
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http://dx.doi.org/10.1111/bjh.14827DOI Listing
August 2017

Increased fracture risk in plasma cell dyscrasias is associated with poorer overall survival.

Br J Haematol 2017 10 27;179(1):61-65. Epub 2017 Jun 27.

Department of Renal Medicine, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.

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http://dx.doi.org/10.1111/bjh.14815DOI Listing
October 2017

Neoplastic plasma cells generate an inflammatory environment within bone marrow and markedly alter the distribution of T cells between lymphoid compartments.

Oncotarget 2017 May;8(18):30383-30394

Institute of Immunology and Immunotherapy, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.

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http://dx.doi.org/10.18632/oncotarget.16628DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444750PMC
May 2017

Telomere length is a critical determinant for survival in multiple myeloma.

Br J Haematol 2017 07 24;178(1):94-98. Epub 2017 Mar 24.

Division of Cancer & Genetics, School of Medicine, Cardiff University, Cardiff, UK.

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http://dx.doi.org/10.1111/bjh.14643DOI Listing
July 2017

Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia.

Nat Commun 2017 02 6;8:14175. Epub 2017 Feb 6.

Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.1038/ncomms14175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303820PMC
February 2017

Guidelines for screening and management of late and long-term consequences of myeloma and its treatment.

Br J Haematol 2017 Mar 20;176(6):888-907. Epub 2017 Jan 20.

University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.

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http://dx.doi.org/10.1111/bjh.14514DOI Listing
March 2017

Panobinostat plus bortezomib and dexamethasone for relapsed myeloma.

Authors:
Guy Pratt

Lancet Haematol 2016 11 14;3(11):e498-e499. Epub 2016 Oct 14.

Centre for Clinical Haematology, University Hospitals Birmingham, Birmingham B15 2TH, UK. Electronic address:

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http://dx.doi.org/10.1016/S2352-3026(16)30133-8DOI Listing
November 2016

A selective histone deacetylase inhibitor for myeloma.

Authors:
Guy Pratt

Lancet Oncol 2016 11 17;17(11):1472-1474. Epub 2016 Sep 17.

University Hospitals Birmingham NHS Foundation Trust, Birmingham B15 2WB, UK. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(16)30407-7DOI Listing
November 2016

Type C TP53-CDKN1A pathway dysfunction occurs independently of CDKN1A gene polymorphisms in chronic lymphocytic leukaemia and is associated with TP53 abnormalities.

Br J Haematol 2017 09 13;178(5):824-826. Epub 2016 Jun 13.

Department of Molecular Pathology, Royal Bournemouth Hospital, Bournemouth, Dorset, UK.

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http://dx.doi.org/10.1111/bjh.14172DOI Listing
September 2017

Augmenting Autologous Stem Cell Transplantation to Improve Outcomes in Myeloma.

Biol Blood Marrow Transplant 2016 11 8;22(11):1926-1937. Epub 2016 Jun 8.

Department of Haematology, Oxford University Hospitals NHS Trust, United Kingdom; NIHR Biomedical Research Centre, Blood Theme, Oxford, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2016.06.004DOI Listing
November 2016

Cytomegalovirus viral load within blood increases markedly in healthy people over the age of 70 years.

Immun Ageing 2016 5;13. Epub 2016 Jan 5.

Institute of Immunology and Immunotherapy, University of Birmingham, Vincent Drive, Birmingham, B152TT UK ; University Hospitals NHS Foundation Trust, Birmingham, UK.

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http://dx.doi.org/10.1186/s12979-015-0056-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700608PMC
January 2016

ATR inhibition induces synthetic lethality and overcomes chemoresistance in TP53- or ATM-defective chronic lymphocytic leukemia cells.

Blood 2016 Feb 12;127(5):582-95. Epub 2015 Nov 12.

School of Cancer Sciences, University of Birmingham, Birmingham, United Kingdom; Centre for Clinical Haematology, Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom;

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http://dx.doi.org/10.1182/blood-2015-05-644872DOI Listing
February 2016

Sclerosing angiomatoid nodular transformation of the spleen.

Clin Case Rep 2015 Oct 10;3(10):888-90. Epub 2015 Sep 10.

Heart of England NHS Foundation Trust Birmingham, U.K.

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http://dx.doi.org/10.1002/ccr3.325DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614664PMC
October 2015

Time to redefine Myeloma.

Br J Haematol 2015 Oct 27;171(1):1-10. Epub 2015 Jul 27.

Department of Haematology, University Hospitals Bristol Foundation Trust, Bristol, UK.

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http://dx.doi.org/10.1111/bjh.13620DOI Listing
October 2015

An oral proteasome inhibitor for multiple myeloma.

Authors:
Guy Pratt

Lancet Oncol 2014 Dec 14;15(13):1417-1418. Epub 2014 Nov 14.

School of Cancer Sciences, University of Birmingham, Edgbaston, Birmingham, UK; Department of Haematology, Birmingham Heartlands Hospital, Birmingham, B9 5SS, UK. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(14)70372-9DOI Listing
December 2014

Guidelines on the diagnosis and investigation of AL amyloidosis.

Br J Haematol 2015 Jan 14;168(2):207-18. Epub 2014 Oct 14.

National Amyloidosis Centre, Division of Medicine, UCL, London, UK.

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http://dx.doi.org/10.1111/bjh.13156DOI Listing
January 2015

Guidelines on the management of AL amyloidosis.

Br J Haematol 2015 Jan 10;168(2):186-206. Epub 2014 Oct 10.

Division of Medicine, National Amyloidosis Centre, UCL, London, UK.

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http://dx.doi.org/10.1111/bjh.13155DOI Listing
January 2015

Proteomics-based strategies to identify proteins relevant to chronic lymphocytic leukemia.

J Proteome Res 2014 Nov 14;13(11):5051-62. Epub 2014 Jul 14.

Institute of Cancer & Genetics, School of Medicine, Cardiff University , Heath Park, Cardiff, CF14 4XN, United Kingdom.

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http://dx.doi.org/10.1021/pr5002803DOI Listing
November 2014

Updates to the guidelines for the diagnosis and management of multiple myeloma.

Br J Haematol 2014 Oct 7;167(1):131-3. Epub 2014 May 7.

School of Cancer Studies, University of Birmingham, Birmingham, UK; Department of Haematology, Heart of England NHS Foundation Trust, Birmingham, UK.

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http://dx.doi.org/10.1111/bjh.12926DOI Listing
October 2014

Development and characterization of a physiologically relevant model of lymphocyte migration in chronic lymphocytic leukemia.

Blood 2014 Jun 17;123(23):3607-17. Epub 2014 Mar 17.

Cardiff Chronic Lymphocytic Leukemia Research Group, Institute of Cancer & Genetics, School of Medicine, Cardiff University, Heath Park, Cardiff, United Kingdom;

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http://dx.doi.org/10.1182/blood-2013-12-544569DOI Listing
June 2014

Lenalidomide and second malignancies in myeloma patients.

Authors:
Guy Pratt

Lancet Oncol 2014 Mar 11;15(3):253-4. Epub 2014 Feb 11.

School of Cancer Sciences, University of Birmingham, Birmingham, B9 5SS, UK; Department of Haematology, Birmingham Heartlands Hospital, Birmingham, B9 5SS, UK. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(14)70001-4DOI Listing
March 2014

A novel Cdk9 inhibitor preferentially targets tumor cells and synergizes with fludarabine.

Oncotarget 2014 Jan;5(2):375-85

Cardiff CLL Research Group, Institute of Cancer and Genetics, School of Medicine, Cardiff University, Heath Park, Cardiff, UK.

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http://www.oncotarget.com/fulltext/1568
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964214PMC
http://dx.doi.org/10.18632/oncotarget.1568DOI Listing
January 2014

Cutaneous plasmablastic lymphoma in a nonimmunocompromised patient.

J Am Acad Dermatol 2013 Dec;69(6):e315-7

Queen Elizabeth Hospital Birmingham, University Hospitals Birmingham National Health Service (NHS) Trust, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jaad.2013.07.003DOI Listing
December 2013

Histone deacetylase inhibitors in multiple myeloma.

Authors:
Guy Pratt

Lancet Oncol 2013 Oct 19;14(11):1038-1039. Epub 2013 Sep 19.

School of Cancer Sciences University of Birmingham, Edgbaston, Birmingham B15 2TT, UK; Department of Haematology, Birmingham Heartlands Hospital, Birmingham, UK. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(13)70425-XDOI Listing
October 2013

The genotype of RAET1L (ULBP6), a ligand for human NKG2D (KLRK1), markedly influences the clinical outcome of allogeneic stem cell transplantation.

Br J Haematol 2012 Dec 1;159(5):589-98. Epub 2012 Oct 1.

School of Cancer Sciences, University of Birmingham, Birmingham, UK.

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http://dx.doi.org/10.1111/bjh.12072DOI Listing
December 2012

Recruitment mechanisms of primary and malignant B cells to the human liver.

Hepatology 2012 Oct;56(4):1521-31

Center for Liver Research, School of Immunity and Infection, University of Birmingham, Birmingham, United Kingdom.

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http://dx.doi.org/10.1002/hep.25790DOI Listing
October 2012

Dominant responses with conservation of T-cell receptor usage in the CD8+ T-cell recognition of a cancer testis antigen peptide presented through HLA-Cw7 in patients with multiple myeloma.

Cancer Immunol Immunother 2011 Dec 23;60(12):1751-61. Epub 2011 Jul 23.

School of Cancer Studies, University of Birmingham, Vincent Drive, Edgbaston, Birmingham B15 2TT, UK.

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http://link.springer.com/10.1007/s00262-011-1070-y
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http://dx.doi.org/10.1007/s00262-011-1070-yDOI Listing
December 2011

Guidelines for the diagnosis and management of multiple myeloma 2011.

Br J Haematol 2011 Jul 14;154(1):32-75. Epub 2011 May 14.

Bristol Haematology and Oncology Centre, University Hospitals Bristol NHS Foundation Trust, Bristol, UK.

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http://dx.doi.org/10.1111/j.1365-2141.2011.08573.xDOI Listing
July 2011

Guidelines for supportive care in multiple myeloma 2011.

Br J Haematol 2011 Jul 22;154(1):76-103. Epub 2011 Apr 22.

Department of Haematology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.

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http://dx.doi.org/10.1111/j.1365-2141.2011.08574.xDOI Listing
July 2011

Free light-chains and renal disorders: when small is worse.

Lancet 2010 Oct;376(9748):1220; author reply 1221-2

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http://dx.doi.org/10.1016/S0140-6736(10)61873-9DOI Listing
October 2010

Chronic graft versus host disease is associated with an immune response to autologous human leukocyte antigen-derived peptides.

Transplantation 2010 Sep;90(5):555-63

Department of Renal Medicine, Queen Elizabeth Hospital Birmingham, UK & School of Immunity, Infection and Inflammation, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.

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http://dx.doi.org/10.1097/TP.0b013e3181e86b58DOI Listing
September 2010

Telomere dysfunction and fusion during the progression of chronic lymphocytic leukemia: evidence for a telomere crisis.

Blood 2010 Sep 10;116(11):1899-907. Epub 2010 Jun 10.

Department of Pathology, School of Medicine, Cardiff University, Heath Park, Cardiff, United Kingdom.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2010-02-27
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http://dx.doi.org/10.1182/blood-2010-02-272104DOI Listing
September 2010

The NF-kappaB inhibitor LC-1 has single agent activity in multiple myeloma cells and synergizes with bortezomib.

Mol Cancer Ther 2010 Jun 1;9(6):1574-82. Epub 2010 Jun 1.

Department of Haematology, School of Medicine, Cardiff University, Cardiff, United Kingdom.

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http://dx.doi.org/10.1158/1535-7163.MCT-10-0104DOI Listing
June 2010

Multiple myeloma with monoclonal free IgG3 heavy chains and free kappa light chains.

Acta Haematol 2010 10;123(3):158-61. Epub 2010 Mar 10.

Department of Immunology, Birmingham Heartlands Hospital, Birmingham, UK.

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https://www.karger.com/Article/FullText/292899
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http://dx.doi.org/10.1159/000292899DOI Listing
April 2010

Images in haematology. Paravertebral extramedullary haemopoiesis associated with pyruvate kinase deficiency.

Br J Haematol 2009 Nov 12;147(3):275. Epub 2009 Feb 12.

Department of Haematology, Birmingham Heartlands Hospital, Birmingham, UK.

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http://dx.doi.org/10.1111/j.1365-2141.2009.07621.xDOI Listing
November 2009

Rel a is an independent biomarker of clinical outcome in chronic lymphocytic leukemia.

J Clin Oncol 2009 Feb 5;27(5):763-9. Epub 2009 Jan 5.

Department of Haematology, School of Medicine, Cardiff University, Heath Park, Cardiff, United Kingdom.

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http://ascopubs.org/doi/10.1200/JCO.2008.19.1114
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http://dx.doi.org/10.1200/JCO.2008.19.1114DOI Listing
February 2009

Differential pattern of CD4+ and CD8+ T-cell immunity to MAGE-A1/A2/A3 in patients with monoclonal gammopathy of undetermined significance (MGUS) and multiple myeloma.

Blood 2008 Oct 24;112(8):3362-72. Epub 2008 Jul 24.

Cancer Research UK Institute for Cancer Studies, University of Birmingham, Birmingham, USA.

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http://dx.doi.org/10.1182/blood-2008-04-149393DOI Listing
October 2008

Selective accumulation of virus-specific CD8+ T cells with unique homing phenotype within the human bone marrow.

Blood 2008 Oct 17;112(8):3293-302. Epub 2008 Jul 17.

Cancer Research UK Institute for Cancer Studies, University of Birmingham, Birmingham, United Kingdom.

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http://dx.doi.org/10.1182/blood-2008-02-138040DOI Listing
October 2008

South Asian chronic lymphocytic leukaemia patients have more rapid disease progression in comparison to White patients.

Br J Haematol 2008 Aug 22;142(4):606-9. Epub 2008 May 22.

CRUK Institute for Cancer Studies, University of Birmingham, Birmingham, UK.

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http://dx.doi.org/10.1111/j.1365-2141.2008.07226.xDOI Listing
August 2008

The evolving use of serum free light chain assays in haematology.

Authors:
Guy Pratt

Br J Haematol 2008 May 3;141(4):413-22. Epub 2008 Mar 3.

CRUK Institute for Cancer Studies, University of Birmingham, Edgbaston, and Department of Haematology, Birmingham Heartlands Hospital, Birmingham, UK.

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http://doi.wiley.com/10.1111/j.1365-2141.2008.07079.x
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http://dx.doi.org/10.1111/j.1365-2141.2008.07079.xDOI Listing
May 2008