Guy Pratt

Guy Pratt

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Guy Pratt

Guy Pratt

Publications by authors named "Guy Pratt"

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100Publications

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National survey of imaging practice for suspected or confirmed plasma cell malignancies.

Br J Radiol 2018 Dec 1;91(1092):20180462. Epub 2018 Nov 1.

1 Cancer Imaging, School of Biomedical Engineering and Imaging Sciences, King's College London , London , UK.

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December 2018

A rare complication of bone marrow aspiration and trephine biopsy: Staphylococcus aureus osteomyelitis and septicaemia.

Br J Haematol 2018 Nov 8. Epub 2018 Nov 8.

University Hospital Birmingham NHS Foundation Trust, Birmingham, UK.

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November 2018

Successful Renal Outcome in Membranoproliferative Glomerulonephritis Following Treatment of the Underlying Subtle Clone: A Case Report.

Mayo Clin Proc Innov Qual Outcomes 2018 Sep 5;2(3):297-302. Epub 2018 Jun 5.

Department of Renal Medicine, University of Birmingham, Birmingham, UK.

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September 2018

Increased fracture risk in plasma cell dyscrasias is associated with poorer overall survival.

Br J Haematol 2017 10 27;179(1):61-65. Epub 2017 Jun 27.

Department of Renal Medicine, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.

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October 2017

Guidelines for the use of imaging in the management of patients with myeloma.

Br J Haematol 2017 08 5;178(3):380-393. Epub 2017 Jul 5.

Department of Haematology, University Hospital Birmingham NHS Foundation Trust, Birmingham, UK.

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August 2017

Telomere length is a critical determinant for survival in multiple myeloma.

Br J Haematol 2017 07 24;178(1):94-98. Epub 2017 Mar 24.

Division of Cancer & Genetics, School of Medicine, Cardiff University, Cardiff, UK.

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July 2017

Neoplastic plasma cells generate an inflammatory environment within bone marrow and markedly alter the distribution of T cells between lymphoid compartments.

Oncotarget 2017 May;8(18):30383-30394

Institute of Immunology and Immunotherapy, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.

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May 2017

Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia.

Nat Commun 2017 02 6;8:14175. Epub 2017 Feb 6.

Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA.

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February 2017

Augmenting Autologous Stem Cell Transplantation to Improve Outcomes in Myeloma.

Biol Blood Marrow Transplant 2016 11 8;22(11):1926-1937. Epub 2016 Jun 8.

Department of Haematology, Oxford University Hospitals NHS Trust, United Kingdom; NIHR Biomedical Research Centre, Blood Theme, Oxford, United Kingdom. Electronic address:

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November 2016

A selective histone deacetylase inhibitor for myeloma.

Authors:
Guy Pratt

Lancet Oncol 2016 11 17;17(11):1472-1474. Epub 2016 Sep 17.

University Hospitals Birmingham NHS Foundation Trust, Birmingham B15 2WB, UK. Electronic address:

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November 2016

Panobinostat plus bortezomib and dexamethasone for relapsed myeloma.

Authors:
Guy Pratt

Lancet Haematol 2016 Nov 14;3(11):e498-e499. Epub 2016 Oct 14.

Centre for Clinical Haematology, University Hospitals Birmingham, Birmingham B15 2TH, UK. Electronic address:

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November 2016

ATR inhibition induces synthetic lethality and overcomes chemoresistance in TP53- or ATM-defective chronic lymphocytic leukemia cells.

Blood 2016 Feb 12;127(5):582-95. Epub 2015 Nov 12.

School of Cancer Sciences, University of Birmingham, Birmingham, United Kingdom; Centre for Clinical Haematology, Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom;

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February 2016

Cytomegalovirus viral load within blood increases markedly in healthy people over the age of 70 years.

Immun Ageing 2016 5;13. Epub 2016 Jan 5.

Institute of Immunology and Immunotherapy, University of Birmingham, Vincent Drive, Birmingham, B152TT UK ; University Hospitals NHS Foundation Trust, Birmingham, UK.

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January 2016

Time to redefine Myeloma.

Br J Haematol 2015 Oct 27;171(1):1-10. Epub 2015 Jul 27.

Department of Haematology, University Hospitals Bristol Foundation Trust, Bristol, UK.

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October 2015

Sclerosing angiomatoid nodular transformation of the spleen.

Clin Case Rep 2015 Oct 10;3(10):888-90. Epub 2015 Sep 10.

Heart of England NHS Foundation Trust Birmingham, U.K.

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October 2015

Guidelines on the management of AL amyloidosis.

Br J Haematol 2015 Jan 10;168(2):186-206. Epub 2014 Oct 10.

Division of Medicine, National Amyloidosis Centre, UCL, London, UK.

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January 2015

Guidelines on the diagnosis and investigation of AL amyloidosis.

Br J Haematol 2015 Jan 14;168(2):207-18. Epub 2014 Oct 14.

National Amyloidosis Centre, Division of Medicine, UCL, London, UK.

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January 2015

An oral proteasome inhibitor for multiple myeloma.

Authors:
Guy Pratt

Lancet Oncol 2014 Dec 14;15(13):1417-8. Epub 2014 Nov 14.

School of Cancer Sciences, University of Birmingham, Edgbaston, Birmingham, UK; Department of Haematology, Birmingham Heartlands Hospital, Birmingham, B9 5SS, UK. Electronic address:

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December 2014

Proteomics-based strategies to identify proteins relevant to chronic lymphocytic leukemia.

J Proteome Res 2014 Nov 14;13(11):5051-62. Epub 2014 Jul 14.

Institute of Cancer & Genetics, School of Medicine, Cardiff University , Heath Park, Cardiff, CF14 4XN, United Kingdom.

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November 2014

Updates to the guidelines for the diagnosis and management of multiple myeloma.

Br J Haematol 2014 Oct 7;167(1):131-3. Epub 2014 May 7.

School of Cancer Studies, University of Birmingham, Birmingham, UK; Department of Haematology, Heart of England NHS Foundation Trust, Birmingham, UK.

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October 2014

Development and characterization of a physiologically relevant model of lymphocyte migration in chronic lymphocytic leukemia.

Blood 2014 Jun 17;123(23):3607-17. Epub 2014 Mar 17.

Cardiff Chronic Lymphocytic Leukemia Research Group, Institute of Cancer & Genetics, School of Medicine, Cardiff University, Heath Park, Cardiff, United Kingdom;

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June 2014

Lenalidomide and second malignancies in myeloma patients.

Authors:
Guy Pratt

Lancet Oncol 2014 Mar 11;15(3):253-4. Epub 2014 Feb 11.

School of Cancer Sciences, University of Birmingham, Birmingham, B9 5SS, UK; Department of Haematology, Birmingham Heartlands Hospital, Birmingham, B9 5SS, UK. Electronic address:

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March 2014

A novel Cdk9 inhibitor preferentially targets tumor cells and synergizes with fludarabine.

Oncotarget 2014 Jan;5(2):375-85

Cardiff CLL Research Group, Institute of Cancer and Genetics, School of Medicine, Cardiff University, Heath Park, Cardiff, UK.

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January 2014

Cutaneous plasmablastic lymphoma in a nonimmunocompromised patient.

J Am Acad Dermatol 2013 Dec;69(6):e315-7

Queen Elizabeth Hospital Birmingham, University Hospitals Birmingham National Health Service (NHS) Trust, United Kingdom. Electronic address:

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December 2013

Histone deacetylase inhibitors in multiple myeloma.

Authors:
Guy Pratt

Lancet Oncol 2013 Oct 19;14(11):1038-1039. Epub 2013 Sep 19.

School of Cancer Sciences University of Birmingham, Edgbaston, Birmingham B15 2TT, UK; Department of Haematology, Birmingham Heartlands Hospital, Birmingham, UK. Electronic address:

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October 2013

Recruitment mechanisms of primary and malignant B cells to the human liver.

Hepatology 2012 Oct;56(4):1521-31

Center for Liver Research, School of Immunity and Infection, University of Birmingham, Birmingham, United Kingdom.

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October 2012

Treatment of chronic lymphocytic leukemia requires targeting of the protective lymph node environment with novel therapeutic approaches.

Leuk Lymphoma 2012 Apr 23;53(4):537-49. Epub 2011 Sep 23.

School of Biosciences, University of Birmingham, Birmingham, UK.

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April 2012

Dominant responses with conservation of T-cell receptor usage in the CD8+ T-cell recognition of a cancer testis antigen peptide presented through HLA-Cw7 in patients with multiple myeloma.

Cancer Immunol Immunother 2011 Dec 23;60(12):1751-61. Epub 2011 Jul 23.

School of Cancer Studies, University of Birmingham, Vincent Drive, Edgbaston, Birmingham B15 2TT, UK.

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December 2011

Guidelines for supportive care in multiple myeloma 2011.

Br J Haematol 2011 Jul 22;154(1):76-103. Epub 2011 Apr 22.

Department of Haematology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.

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July 2011

Guidelines for the diagnosis and management of multiple myeloma 2011.

Br J Haematol 2011 Jul 14;154(1):32-75. Epub 2011 May 14.

Bristol Haematology and Oncology Centre, University Hospitals Bristol NHS Foundation Trust, Bristol, UK.

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July 2011

Free light-chains and renal disorders: when small is worse.

Lancet 2010 Oct;376(9748):1220; author reply 1221-2

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October 2010

Telomere dysfunction and fusion during the progression of chronic lymphocytic leukemia: evidence for a telomere crisis.

Blood 2010 Sep 10;116(11):1899-907. Epub 2010 Jun 10.

Department of Pathology, School of Medicine, Cardiff University, Heath Park, Cardiff, United Kingdom.

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September 2010

Chronic graft versus host disease is associated with an immune response to autologous human leukocyte antigen-derived peptides.

Transplantation 2010 Sep;90(5):555-63

Department of Renal Medicine, Queen Elizabeth Hospital Birmingham, UK & School of Immunity, Infection and Inflammation, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.

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September 2010

The NF-kappaB inhibitor LC-1 has single agent activity in multiple myeloma cells and synergizes with bortezomib.

Mol Cancer Ther 2010 Jun 1;9(6):1574-82. Epub 2010 Jun 1.

Department of Haematology, School of Medicine, Cardiff University, Cardiff, United Kingdom.

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June 2010

Multiple myeloma with monoclonal free IgG3 heavy chains and free kappa light chains.

Acta Haematol 2010 10;123(3):158-61. Epub 2010 Mar 10.

Department of Immunology, Birmingham Heartlands Hospital, Birmingham, UK.

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April 2010

Images in haematology. Paravertebral extramedullary haemopoiesis associated with pyruvate kinase deficiency.

Br J Haematol 2009 Nov 12;147(3):275. Epub 2009 Feb 12.

Department of Haematology, Birmingham Heartlands Hospital, Birmingham, UK.

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November 2009

Rel a is an independent biomarker of clinical outcome in chronic lymphocytic leukemia.

J Clin Oncol 2009 Feb 5;27(5):763-9. Epub 2009 Jan 5.

Department of Haematology, School of Medicine, Cardiff University, Heath Park, Cardiff, United Kingdom.

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February 2009

Differential pattern of CD4+ and CD8+ T-cell immunity to MAGE-A1/A2/A3 in patients with monoclonal gammopathy of undetermined significance (MGUS) and multiple myeloma.

Blood 2008 Oct 24;112(8):3362-72. Epub 2008 Jul 24.

Cancer Research UK Institute for Cancer Studies, University of Birmingham, Birmingham, USA.

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October 2008

South Asian chronic lymphocytic leukaemia patients have more rapid disease progression in comparison to White patients.

Br J Haematol 2008 Aug 22;142(4):606-9. Epub 2008 May 22.

CRUK Institute for Cancer Studies, University of Birmingham, Birmingham, UK.

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August 2008

The evolving use of serum free light chain assays in haematology.

Authors:
Guy Pratt

Br J Haematol 2008 May 3;141(4):413-22. Epub 2008 Mar 3.

CRUK Institute for Cancer Studies, University of Birmingham, Edgbaston, and Department of Haematology, Birmingham Heartlands Hospital, Birmingham, UK.

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May 2008

Immunodeficiency and immunotherapy in multiple myeloma.

Br J Haematol 2007 Sep;138(5):563-79

CRUK Institute for Cancer Studies, University of Birmingham, Birmingham, UK.

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September 2007

Two germ line polymorphisms of the tumour suppressor gene p53 may influence the biology of chronic lymphocytic leukaemia.

Leuk Res 2006 Sep 3;30(9):1113-8. Epub 2006 Feb 3.

Department of Haematology, Heart of England NHS Trust, Bordesley Green East, Birmingham, UK.

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September 2006

CD8+ T cells specific for cancer germline gene antigens are found in many patients with multiple myeloma, and their frequency correlates with disease burden.

Blood 2005 Dec 6;106(13):4217-24. Epub 2005 Sep 6.

CR UK Institute for Cancer Studies and Department of Haematology, Queen Elizabeth Hospital, Birmingham.

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December 2005

Cryoglobulinaemia as an acute presentation of Waldenstrom's macroglobulinaemia.

Br J Haematol 2004 Mar;124(5):565

Department of Medicine, Birmingham Heartlands Hospital, Birmingham, UK.

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March 2004

Long distance vectorette PCR (LDV PCR).

Methods Mol Biol 2002 ;192:275-84

Department of Molecular Oncology, University of Leeds, Leeds, UK.

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June 2003