Guy Macgowan

Guy Macgowan

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Guy Macgowan

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Effects of drug abuse, smoking and alcohol on donor hearts and lungs.

Transpl Int 2019 Oct 28;32(10):1019-1027. Epub 2019 Jun 28.

Department of Cardiothoracic Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1111/tri.13468DOI Listing
October 2019

The role of exercise haemodynamics in assessing patients with chronic heart failure and left ventricular assist devices.

Expert Rev Med Devices 2019 Oct 4. Epub 2019 Oct 4.

Institute of Cellular and Genetic Medicine, Cardiovascular Research Centre, Faculty of Medical Sciences, Newcastle University, and Newcastle upon Tyne Hospitals , Newcastle upon Tyne , UK.

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http://dx.doi.org/10.1080/17434440.2019.1675506DOI Listing
October 2019

Outcome following heart transplant assessment in adults with congenital heart disease.

Heart 2019 Jul 5. Epub 2019 Jul 5.

Adult Congenital and Pediatric Heart Unit, Freeman Hospital Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, UK.

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http://dx.doi.org/10.1136/heartjnl-2019-314711DOI Listing
July 2019

NT-proBNP is a weak indicator of cardiac function and haemodynamic response to exercise in chronic heart failure.

ESC Heart Fail 2019 Apr 20;6(2):449-454. Epub 2019 Feb 20.

Cardiovascular Research Centre, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1002/ehf2.12424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437429PMC
April 2019

Association between heart rate variability and haemodynamic response to exercise in chronic heart failure.

Scand Cardiovasc J 2019 Apr 8;53(2):77-82. Epub 2019 Apr 8.

a Faculty of Medical Sciences, Cardiovascular Research Centre, Institutes of Cellular and Genetic Medicine , Newcastle University, and Newcastle upon Tyne Hospitals , Newcastle upon Tyne , UK.

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http://dx.doi.org/10.1080/14017431.2019.1590629DOI Listing
April 2019

Impact of donor variables on heart transplantation outcomes in mechanically bridged versus standard recipients†.

Interact Cardiovasc Thorac Surg 2019 03;28(3):455-464

Department of Cardiology, Freeman Hospital, Newcastle upon Tyne, UK.

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https://academic.oup.com/icvts/advance-article/doi/10.1093/i
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http://dx.doi.org/10.1093/icvts/ivy262DOI Listing
March 2019

High intensity interval training protects the heart during increased metabolic demand in patients with type 2 diabetes: a randomised controlled trial.

Acta Diabetol 2019 Mar 1;56(3):321-329. Epub 2018 Nov 1.

Faculty of Medical Sciences, Cardiovascular Research Centre, Institutes of Cellular and Genetic Medicine, Newcastle University, 4th Floor William Leech Building M4.074, Newcastle upon Tyne, NE2 4HH, UK.

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http://link.springer.com/10.1007/s00592-018-1245-5
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http://dx.doi.org/10.1007/s00592-018-1245-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394729PMC
March 2019

Exercise Hemodynamics to Evaluate the Breathless Patient: Defining the Normal Pulmonary Arterial Wedge Pressure.

J Card Fail 2019 02 5;25(2):123-124. Epub 2018 Dec 5.

Institutes of Genetic Medicine and Cellular Medicine, Cardiovascular Research Centre, Newcastle University, Newcastle Upon Tyne, United Kingdom.

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http://dx.doi.org/10.1016/j.cardfail.2018.11.018DOI Listing
February 2019

Cardiac function is not associated with glucose control in older women.

Exp Gerontol 2019 Feb 20;116:31-36. Epub 2018 Dec 20.

Cardiovascular Research Centre, Institutes of Cellular and Genetic Medicine, Newcastle University, UK; Freeman Hospital and Royal Victoria Infirmary, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK; RCUK Newcastle Centre for Ageing and Vitality, Newcastle University, Newcastle upon Tyne, UK. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S05315565183029
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http://dx.doi.org/10.1016/j.exger.2018.12.014DOI Listing
February 2019

Reproducibility of Inert Gas Rebreathing Method to Estimate Cardiac Output at Rest and During Cardiopulmonary Exercise Stress Testing.

Int J Sports Med 2019 Feb 3;40(2):125-132. Epub 2019 Jan 3.

Institute of Cellular Medicine, Newcastle university, Newcastle Upon Tyne, United Kingdom of Great Britain and Northern Ireland.

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http://dx.doi.org/10.1055/a-0809-5408DOI Listing
February 2019

Donor and recipient risk factor analysis of inferior postheart transplantation outcome in the era of durable mechanical assist devices.

Clin Transplant 2018 10 18;32(10):e13390. Epub 2018 Sep 18.

Department of Cardiology, Freeman Hospital, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1111/ctr.13390DOI Listing
October 2018

A novel cardiac output response to stress test developed to improve diagnosis and monitoring of heart failure in primary care.

ESC Heart Fail 2018 08 26;5(4):703-712. Epub 2018 Jun 26.

Cardiovascular Research Centre, Institutes of Cellular and Genetic Medicine, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1002/ehf2.12302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073030PMC
August 2018

First-in-man use of the MVAD axial-flow pump: Long-term outcome.

J Heart Lung Transplant 2018 07 25;37(7):933-936. Epub 2018 Apr 25.

Department of Cardiothoracic Surgery, Freeman Hospital, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1016/j.healun.2018.04.012DOI Listing
July 2018

'We're like a gang, we stick together': experiences of ventricular assist device communities.

Eur J Cardiovasc Nurs 2018 06 19;17(5):399-407. Epub 2018 Jan 19.

1 Faculty of Health and Life Sciences, Northumbria University, UK.

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http://dx.doi.org/10.1177/1474515118754738DOI Listing
June 2018

Comparison of cardiac output estimates by bioreactance and inert gas rebreathing methods during cardiopulmonary exercise testing.

Clin Physiol Funct Imaging 2018 May 2;38(3):483-490. Epub 2017 Jun 2.

Institute of Cellular Medicine, Medical School, Newcastle University, Newcastle Upon Tyne, UK.

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http://dx.doi.org/10.1111/cpf.12442DOI Listing
May 2018

Myocardial Recovery Strategy with Decommissioning for the HeartWare Left Ventricular Assist Device.

ASAIO J 2017 May/Jun;63(3):299-304

From the *Department of Cardiology Freeman Hospital and †Institute of Genetic Medicine, Newcastle University, United Kingdom; and ‡Department of Cardiothoracic Surgery and §Department of Microbiology, Freeman Hospital, Newcastle upon Tyne, United Kingdom.

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http://Insights.ovid.com/crossref?an=00002480-201705000-0001
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http://dx.doi.org/10.1097/MAT.0000000000000523DOI Listing
January 2018

Impact of age on the association between cardiac high-energy phosphate metabolism and cardiac power in women.

Heart 2018 01 12;104(2):111-118. Epub 2017 Jun 12.

Institute of Cellular Medicine, Newcastle Magnetic Resonance Centre, Medical School, Newcastle University, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1136/heartjnl-2017-311275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861386PMC
January 2018

'Being' a ventricular assist device recipient: A liminal existence.

Soc Sci Med 2017 10 19;190:141-148. Epub 2017 Aug 19.

Faculty of Health and Life Sciences, Northumbria University, Newcastle Upon Tyne, NE1 8ST, United Kingdom.

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http://dx.doi.org/10.1016/j.socscimed.2017.08.016DOI Listing
October 2017

Giant cell myocarditis presenting with acute heart failure.

BMJ Case Rep 2017 May 22;2017. Epub 2017 May 22.

University of Hull, Hull, UK.

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http://dx.doi.org/10.1136/bcr-2017-219574DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753742PMC
May 2017

Diffusion Tensor Magnetic Resonance Imaging of the Heart: Looking Into the Layers of the Myocardium.

J Am Coll Cardiol 2017 02;69(6):677-678

Centre for In Vivo Imaging, Newcastle University, Newcastle upon Tyne, United Kingdom; Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Newcastle Magnetic Resonance Centre, Newcastle University, Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.1016/j.jacc.2016.10.080DOI Listing
February 2017

Impact of aortic valve closure on adverse events and outcomes with the HeartWare ventricular assist device.

J Heart Lung Transplant 2017 01 18;36(1):42-49. Epub 2016 Aug 18.

Cardiothoracic Directorate, Freeman Hospital, Newcastle upon Tyne Hospitals. NHS Foundation Trust, Newcastle upon Tyne, United Kingdom; Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.healun.2016.08.006DOI Listing
January 2017

Normal age-related changes in left ventricular function: Role of afterload and subendocardial dysfunction.

Int J Cardiol 2016 Nov 30;223:306-312. Epub 2016 Jul 30.

Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Centre for In Vivo Imaging, Newcastle University, Newcastle upon Tyne, United Kingdom; Dept. of Cardiology, Freeman Hospital, Newcastle upon Tyne, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2016.07.252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073997PMC
November 2016

Pregnancy in cardiac transplant recipients.

Clin Transplant 2016 09 25;30(9):1059-65. Epub 2016 Jul 25.

Departments of Cardiothoracic Surgery and Cardiopulmonary Transplantation, Freeman Hospital, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1111/ctr.12788DOI Listing
September 2016

An Extended Role of Continuous Flow Device in Pediatric Mechanical Circulatory Support.

Ann Thorac Surg 2016 Aug 26;102(2):620-7. Epub 2016 Apr 26.

Cardiopulmonary Transplant Unit, Freeman Hospital, Newcastle Upon Tyne, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.athoracsur.2016.02.013DOI Listing
August 2016

Reduced cardiac volumes in chronic fatigue syndrome associate with plasma volume but not length of disease: a cohort study.

Open Heart 2016 24;3(1):e000381. Epub 2016 Jun 24.

Institute of Cellular Medicine, Newcastle upon Tyne, UK; Newcastle Magnetic Resonance Centre, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1136/openhrt-2015-000381DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932290PMC
July 2016

The Challenge of Radiation-Induced Restrictive Cardiomyopathy and Outcomes After Heart Transplantation.

Authors:
Guy A MacGowan

J Card Fail 2016 Jun 12;22(6):479-80. Epub 2016 Apr 12.

Department of Cardiology, Freeman Hospital, Newcastle upon Tyne, United Kingdom; Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.cardfail.2016.04.006DOI Listing
June 2016

Development of de novo aortic valve incompetence in patients with the continuous-flow HeartWare ventricular assist device.

J Heart Lung Transplant 2016 Mar 19;35(3):312-319. Epub 2015 Oct 19.

Cardiothoracic Surgery; Cardiopulmonary Transplantation, Freeman Hospital, Newcastle upon Tyne, UK. Electronic address:

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http://dx.doi.org/10.1016/j.healun.2015.10.022DOI Listing
March 2016

Measurement of pulse wave velocity in normal ageing: comparison of Vicorder and magnetic resonance phase contrast imaging.

BMC Cardiovasc Disord 2016 Feb 19;16:50. Epub 2016 Feb 19.

Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1186/s12872-016-0224-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759948PMC
February 2016

The effect of age on the relationship between cardiac and vascular function.

Mech Ageing Dev 2016 Jan 15;153:1-6. Epub 2015 Nov 15.

Institute of Cellular Medicine, MoveLab, Medical School, Newcastle University, Newcastle upon Tyne, UK; RCUK Centre for Ageing and Vitality, Newcastle University, Newcastle upon Tyne, UK. Electronic address:

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http://dx.doi.org/10.1016/j.mad.2015.11.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762231PMC
January 2016

Association of aging, arterial stiffness, and cardiovascular disease: a review.

Cardiol Rev 2014 Sep-Oct;22(5):223-32

From the *Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, Newcastle-upon-Tyne, United Kingdom; †Institute of Ageing and Health, Faculty of Medical Sciences, Newcastle University, Newcastle-upon-Tyne, United Kingdom; ‡Cardiothoracic Centre, Freeman Hospital, Newcastle-upon-Tyne Hospitals NHS Foundation Trust, Newcastle-upon-Tyne, United Kingdom; §Department of Biochemistry, Newcastle-upon-Tyne Hospitals NHS Foundation Trust, Newcastle-upon-Tyne, United Kingdom.

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http://dx.doi.org/10.1097/CRD.0000000000000009DOI Listing
April 2015

Absence of Cardiac Benefit with Early Combination ACE Inhibitor and Beta Blocker Treatment in mdx Mice.

J Cardiovasc Transl Res 2015 Apr 21;8(3):198-207. Epub 2015 Apr 21.

Institute of Genetic Medicine, Newcastle University, International Centre for Life, Central Parkway, Newcastle Upon Tyne, NE1 3BZ, UK.

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http://dx.doi.org/10.1007/s12265-015-9623-7DOI Listing
April 2015

Considerations for patients awaiting heart transplantation-Insights from the UK experience.

J Thorac Dis 2015 Mar;7(3):527-31

1 Department of Cardiology, Freeman Hospital, Newcastle upon Tyne NE7 7DN, UK ; 2 Institute of Medical Genetics, Newcastle University, Newcastle upon Tyne NE1 3BZ, UK ; 3 Department of Paediatric Cardiology, 4 Department of Paediatric Cardiothoracic Surgery, 5 Department of Cardiothoracic Surgery, Freeman Hospital, Newcastle upon Tyne NE7 7DN, UK.

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http://dx.doi.org/10.3978/j.issn.2072-1439.2015.01.07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387430PMC
March 2015

Assessment of ventricular function in mouse models of muscular dystrophy: a comparison of MRI with conductance catheter.

Neuromuscul Disord 2015 Jan 6;25(1):24-31. Epub 2014 Oct 6.

Institute of Genetic Medicine, Newcastle University, International Centre for Life, Central Parkway, Newcastle Upon Tyne NE1 3BZ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.nmd.2014.09.013DOI Listing
January 2015

Effect of physical activity on age-related changes in cardiac function and performance in women.

Circ Cardiovasc Imaging 2015 Jan 30;8(1). Epub 2014 Dec 30.

From the Institute of Cellular Medicine, Newcastle Magnetic Resonance Centre (D.G.J., L.P., A.M.B., R.T., K.G.H., M.I.T.); MRC Centre for Ageing and Vitality (D.G.J., M.I.T.), and Department of Cardiology, Freeman Hospital (G.A.M.), Newcastle University, Newcastle upon Tyne, United Kingdom; and Institute for Genetic Medicine, Newcastle upon Tyne, United Kingdom (G.A.M.).

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http://dx.doi.org/10.1161/CIRCIMAGING.114.002086DOI Listing
January 2015

Durable ventricular assist device support for failing systemic morphologic right ventricle: early results.

Ann Thorac Surg 2014 Dec 22;98(6):2122-9. Epub 2014 Oct 22.

Children's Heart Unit, Freeman Hospital, Newcastle Upon Tyne, United Kingdom; Cardiopulmonary Transplant Unit, Freeman Hospital, Newcastle Upon Tyne, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.athoracsur.2014.06.054DOI Listing
December 2014

Bioimpedance and bioreactance methods for monitoring cardiac output.

Best Pract Res Clin Anaesthesiol 2014 Dec 23;28(4):381-94. Epub 2014 Sep 23.

Department of Cardiology, Freeman Hospital, Newcastle upon Tyne, UK; Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK. Electronic address:

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http://dx.doi.org/10.1016/j.bpa.2014.09.003DOI Listing
December 2014

Four-year outcomes with third-generation centrifugal left ventricular assist devices in an era of restricted transplantation.

Eur J Cardiothorac Surg 2014 Sep 30;46(3):e35-40. Epub 2014 Jun 30.

Department of Cardiology, Freeman Hospital, Newcastle upon Tyne, UK Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK

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http://dx.doi.org/10.1093/ejcts/ezu258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128784PMC
September 2014

Effect of left ventricular assist device implantation and heart transplantation on habitual physical activity and quality of life.

Am J Cardiol 2014 Jul 18;114(1):88-93. Epub 2014 Apr 18.

Department of Cardiology, Freeman Hospital, Newcastle upon Tyne, United Kingdom; Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.1016/j.amjcard.2014.04.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061472PMC
July 2014

Management issues during HeartWare left ventricular assist device implantation and the role of transesophageal echocardiography.

Ann Card Anaesth 2013 Oct-Dec;16(4):259-67

Department of Cardiothoracic Anaesthesia, Freeman Hospital, High Heaton, Newcastle Upon Tyne, NE7 7DN, United Kingdom.

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http://dx.doi.org/10.4103/0971-9784.119173DOI Listing
June 2014

Defining cardiac adaptations and safety of endurance training in patients with m.3243A>G-related mitochondrial disease.

Int J Cardiol 2013 Oct 3;168(4):3599-608. Epub 2013 Jun 3.

Wellcome Trust Centre for Mitochondrial Research, Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne NE2 4HH, UK; Cardiothoracic Centre, Freeman Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne NE7 7DN, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2013.05.062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819621PMC
October 2013

Trends in long-term mechanical circulatory support for advanced heart failure in the UK.

Eur J Heart Fail 2013 Oct 30;15(10):1185-93. Epub 2013 Jul 30.

Clinical Effectiveness Unit, The Royal College of Surgeons of England, London, UK.

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http://dx.doi.org/10.1093/eurjhf/hft127DOI Listing
October 2013

Subepicardial dysfunction leads to global left ventricular systolic impairment in patients with limb girdle muscular dystrophy 2I.

Eur J Heart Fail 2013 Sep 10;15(9):986-94. Epub 2013 Apr 10.

Newcastle Magnetic Resonance Centre, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1093/eurjhf/hft057DOI Listing
September 2013

Beta-blockers, left and right ventricular function, and in-vivo calcium influx in muscular dystrophy cardiomyopathy.

PLoS One 2013 20;8(2):e57260. Epub 2013 Feb 20.

Institute of Genetic Medicine, Newcastle University, International Centre for Life, Central Parkway, Newcastle upon Tyne, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0057260PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577707PMC
August 2013

Editorial comment: Ventricular assist devices for advanced heart failure: evidence that cannot be ignored.

Eur J Cardiothorac Surg 2013 Jun 22;43(6):1242-3. Epub 2013 Jan 22.

Department of Cardiology, Freeman Hospital, Newcastle upon Tyne, UK.

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https://academic.oup.com/ejcts/article-lookup/doi/10.1093/ej
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http://dx.doi.org/10.1093/ejcts/ezs636DOI Listing
June 2013

Cardiac structure and function are altered in adults with non-alcoholic fatty liver disease.

J Hepatol 2013 Apr 22;58(4):757-62. Epub 2012 Nov 22.

Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1016/j.jhep.2012.11.015DOI Listing
April 2013

Heterogeneous abnormalities of in-vivo left ventricular calcium influx and function in mouse models of muscular dystrophy cardiomyopathy.

J Cardiovasc Magn Reson 2013 Jan 16;15. Epub 2013 Jan 16.

Institute of Genetic Medicine, Newcastle University, International Center for Life, Newcastle, UK.

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http://dx.doi.org/10.1186/1532-429X-15-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564732PMC
January 2013

Cardiomyopathy is common in patients with the mitochondrial DNA m.3243A>G mutation and correlates with mutation load.

Neuromuscul Disord 2012 Jul 17;22(7):592-6. Epub 2012 Apr 17.

Newcastle Magnetic Resonance Centre, Institute of Cellular Medicine, Newcastle University, Campus for Ageing and Vitality, NE4 5PL, UK.

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http://dx.doi.org/10.1016/j.nmd.2012.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387369PMC
July 2012

Cardiac torsion-strain relationships in fatigued primary biliary cirrhosis patients show accelerated aging: a pilot cross-sectional study.

J Appl Physiol (1985) 2012 Jun 29;112(12):2043-8. Epub 2012 Mar 29.

Newcastle Magnetic Resonance Centre and Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.1152/japplphysiol.00195.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378393PMC
June 2012

Right heart failure after left ventricular assist device implantation: early and late.

Curr Opin Cardiol 2012 May;27(3):296-300

Departments of Cardiology, Freeman Hospital, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1097/HCO.0b013e3283511e60DOI Listing
May 2012

Left ventricular torsion, energetics, and diastolic function in normal human aging.

Am J Physiol Heart Circ Physiol 2012 Feb 16;302(4):H885-92. Epub 2011 Dec 16.

Newcastle Magnetic Resonance Centre, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.1152/ajpheart.00985.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322734PMC
February 2012

The decline in heart transplantation in the UK.

BMJ 2011 May 5;342:d2483. Epub 2011 May 5.

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http://dx.doi.org/10.1136/bmj.d2483DOI Listing
May 2011

Intolerance to ß-blockade in a mouse model of δ-sarcoglycan-deficient muscular dystrophy cardiomyopathy.

Eur J Heart Fail 2010 Nov 30;12(11):1163-70. Epub 2010 Jul 30.

Institute of Human Genetics, Newcastle University, International Center for Life, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1093/eurjhf/hfq129DOI Listing
November 2010

Circadian variation of human ventricular fibrillation dominant frequency.

Resuscitation 2010 Aug 24;81(8):950-5. Epub 2010 Apr 24.

Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, NE7 7DN, UK.

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http://dx.doi.org/10.1016/j.resuscitation.2010.03.026DOI Listing
August 2010

Attenuation of adverse cardiac effects in prednisolone-treated delta-sarcoglycan-deficient mice by mineralocorticoid-receptor-antagonism.

Neuromuscul Disord 2010 Jan 12;20(1):21-8. Epub 2009 Nov 12.

Institute of Human Genetics, Newcastle University, International Centre for Life, Newcastle upon Tyne NE1 3BZ, UK.

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http://dx.doi.org/10.1016/j.nmd.2009.10.003DOI Listing
January 2010

Sildenafil citrate augments myocardial protection in heart transplantation.

Transplantation 2010 Jan;89(2):169-77

Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.1097/TP.0b013e3181c42b22DOI Listing
January 2010

Left ventricular and myocardial function in mice expressing constitutively pseudophosphorylated cardiac troponin I.

Circ Res 2009 Dec 22;105(12):1232-9. Epub 2009 Oct 22.

Cardiovascular Systems Laboratory, Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15219, USA.

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http://dx.doi.org/10.1161/CIRCRESAHA.109.205427DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862555PMC
December 2009

Acute hemodynamic effects of intravenous sildenafil citrate in congestive heart failure: comparison of phosphodiesterase type-3 and -5 inhibition.

J Heart Lung Transplant 2009 Jul 13;28(7):676-82. Epub 2009 May 13.

Department of Cardiopulmonary Transplantation, Freeman Hospital, Newcastle upon Tyne, United Kingdom.

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http://linkinghub.elsevier.com/retrieve/pii/S105324980900235
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http://dx.doi.org/10.1016/j.healun.2009.04.013DOI Listing
July 2009

Contrasting effects of steroids and angiotensin-converting-enzyme inhibitors in a mouse model of dystrophin-deficient cardiomyopathy.

Eur J Heart Fail 2009 May 20;11(5):463-71. Epub 2009 Feb 20.

Institute of Human Genetics, Newcastle University, International Center for Life, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1093/eurjhf/hfp028DOI Listing
May 2009

Good news for mice with heart attacks: preventing acute myocardial injury by inhibiting apoptosis.

Authors:
Guy A MacGowan

Cardiovasc Res 2009 Jan 5;81(1):1-2. Epub 2008 Nov 5.

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http://dx.doi.org/10.1093/cvr/cvn300DOI Listing
January 2009

Dynamic analysis of exercise oxygen consumption predicts outcomes in advanced heart failure.

Congest Heart Fail 2007 Nov-Dec;13(6):313-8

Freeman Hospital, Newcastle upon Tyne, UK.

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January 2008

Pressure-calcium relationships in perfused mouse hearts.

Am J Physiol Heart Circ Physiol 2006 Jun 13;290(6):H2614-24. Epub 2006 Jan 13.

Cardiovascular Institute, University of Pittsburgh, 749 Benedum Hall, Pittsburgh, PA 15261, USA.

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http://dx.doi.org/10.1152/ajpheart.00979.2005DOI Listing
June 2006

What is the in vivo mechanism of action of levosimendan?

Authors:
Guy A MacGowan

J Card Fail 2005 Aug;11(6):482; author reply 482-3

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http://dx.doi.org/10.1016/j.cardfail.2005.07.001DOI Listing
August 2005

The myofilament force-calcium relationship as a target for positive inotropic therapy in congestive heart failure.

Authors:
Guy A MacGowan

Cardiovasc Drugs Ther 2005 May;19(3):203-10

Dept of Cardiology, Freeman Hospital and University of Newcastle upon Tyne, Newcastle upon Tyne NE7 7DN, United Kingdom.

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http://dx.doi.org/10.1007/s10557-005-2465-9DOI Listing
May 2005

In vivo alpha-adrenergic responses and troponin I phosphorylation: anesthesia interactions.

J Appl Physiol (1985) 2005 Apr 3;98(4):1163-70. Epub 2004 Dec 3.

Freeman Hospital, Dept of Cardiology, Newcastle upon Tyne NE7 7DN, UK.

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http://dx.doi.org/10.1152/japplphysiol.00959.2004DOI Listing
April 2005

Intermittent outpatient ultrafiltration for the treatment of severe refractory congestive heart failure.

J Card Fail 2004 Oct;10(5):380-3

Cardiovascular Institute, University of Pittsburgh Medical Center, Pennsylvania 15213, USA.

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October 2004

Interaction of implantable defibrillator therapy with angiotensin-converting enzyme deletion/insertion polymorphism.

J Cardiovasc Electrophysiol 2004 Oct;15(10):1162-6

Cardiovascular Institute, University of Pittsburgh, Pittsburgh, Pennsylvania 15213-2582, USA.

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http://dx.doi.org/10.1046/j.1540-8167.2004.03609.xDOI Listing
October 2004

Troponin I protein kinase C phosphorylation sites and ventricular function.

Cardiovasc Res 2004 Aug;63(2):245-55

Cardiovascular Institute, University of Pittsburgh, Pittsburgh, PA 15261, USA.

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http://dx.doi.org/10.1016/j.cardiores.2004.04.010DOI Listing
August 2004

Effect of the TNF-alpha-promoter polymorphism on cardiac allograft rejection.

J Heart Lung Transplant 2004 Jun;23(6):696-700

Cardiovascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1016/j.healun.2003.07.012DOI Listing
June 2004

Decreasing motion artifacts in calcium-dependent fluorescence transients from the perfused mouse heart using frequency filtering.

Cell Calcium 2004 Feb;35(2):141-53

Medical Department, Brookhaven National Laboratory, Upton, NY 11794, USA.

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http://dx.doi.org/10.1016/j.ceca.2003.08.005DOI Listing
February 2004

Effect of the Asp298 variant of endothelial nitric oxide synthase on survival for patients with congestive heart failure.

Circulation 2003 Apr 17;107(12):1598-602. Epub 2003 Mar 17.

Heart Failure Section, Cardiovascular Institute, University of Pittsburgh Medical Center, 558 Scaife Hall, 200 Lothrop St, Pittsburgh, Pa 15213, USA.

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http://circ.ahajournals.org/content/107/12/1598.full.pdf
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http://dx.doi.org/10.1161/01.CIR.0000060540.93836.AADOI Listing
April 2003

Selected patients listed for cardiac transplantation may benefit from defibrillator implantation regardless of an established indication.

J Heart Lung Transplant 2003 Apr;22(4):411-8

Electrophysiology Division of the Cardiovascular Institute, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA.

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http://dx.doi.org/10.1016/s1053-2498(02)00573-9DOI Listing
April 2003

Impact of beta-blocker therapy on functional capacity criteria for heart transplant listing.

J Heart Lung Transplant 2003 Jan;22(1):78-86

Cardiovascular Institute, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1016/s1053-2498(02)00480-1DOI Listing
January 2003

Clinical importance of beta-adrenoceptor polymorphisms in cardiovascular disease.

Am J Pharmacogenomics 2002 ;2(2):73-8

Department of Medicine, Heart Failure Section, University of Pittsburgh, Pittsburgh, Pennsylvania 15213-2582, USA.

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December 2002