Guy G Brusselle

Guy G Brusselle

UNVERIFIED PROFILE

Are you Guy G Brusselle?   Register this Author

Register author
Guy G Brusselle

Guy G Brusselle

Publications by authors named "Guy G Brusselle"

Are you Guy G Brusselle?   Register this Author

100Publications

3287Reads

45Profile Views

Prevalence and burden of asthma in China: time to act.

Lancet 2019 08 20;394(10196):364-366. Epub 2019 Jun 20.

Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S0140-6736(19)31349-2DOI Listing
August 2019

Prevalence of Asthma and COPD and Blood Eosinophil Count in a Middle-Aged Belgian Population.

J Clin Med 2019 Jul 28;8(8). Epub 2019 Jul 28.

Department of Cardiology and Biobanking and Cardiovascular Epidemiology, Ghent University Hospital and Ghent University, Corneel Heymanslaan 10, 9000 Ghent, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/jcm8081122DOI Listing
July 2019

GDF-15 in Pulmonary and Critical Care Medicine.

Am J Respir Cell Mol Biol 2019 Jun;60(6):621-628

2 Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, and.

View Article

Download full-text PDF

Source
https://www.atsjournals.org/doi/10.1165/rcmb.2018-0379TR
Publisher Site
http://dx.doi.org/10.1165/rcmb.2018-0379TRDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543753PMC
June 2019

The once-daily fixed-dose combination of olodaterol and tiotropium in the management of COPD: current evidence and future prospects.

Ther Adv Respir Dis 2019 Jan-Dec;13:1753466619843426

Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1753466619843426DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475840PMC
April 2019

Chronic obstructive pulmonary disease and the development of atrial fibrillation.

Int J Cardiol 2019 Feb 15;276:118-124. Epub 2018 Sep 15.

Department of Epidemiology, Erasmus Medical Center, PO Box 2040, Rotterdam 3000, CA, the Netherlands; Department of Bioanalysis, FFW, Ghent University, Ottergemsesteenweg 460, 9000 Ghent, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijcard.2018.09.056DOI Listing
February 2019

IL-33 signalling contributes to pollutant-induced allergic airway inflammation.

Clin Exp Allergy 2018 Dec 19;48(12):1665-1675. Epub 2018 Sep 19.

Department of Respiratory Medicine, Laboratory for Translational Research in Obstructive Pulmonary Diseases, Ghent University Hospital, Ghent, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/cea.13261DOI Listing
December 2018

Association of innate defense proteins BPIFA1 and BPIFB1 with disease severity in COPD.

Int J Chron Obstruct Pulmon Dis 2018 19;13:11-27. Epub 2017 Dec 19.

Laboratory for Translational Research in Obstructive Pulmonary Diseases, Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2147/COPD.S144136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741069PMC
September 2018

Influence of genetic variants on childhood lung function - The Generation R Study.

Pediatr Allergy Immunol 2018 09 10;29(6):589-595. Epub 2018 Jul 10.

Department of Pediatrics, Division of Respiratory Medicine and Allergology, Division of Neonatology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/pai.12931DOI Listing
September 2018

Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function.

Authors:
Annah B Wyss Tamar Sofer Mi Kyeong Lee Natalie Terzikhan Jennifer N Nguyen Lies Lahousse Jeanne C Latourelle Albert Vernon Smith Traci M Bartz Mary F Feitosa Wei Gao Tarunveer S Ahluwalia Wenbo Tang Christopher Oldmeadow Qing Duan Kim de Jong Mary K Wojczynski Xin-Qun Wang Raymond Noordam Fernando Pires Hartwig Victoria E Jackson Tianyuan Wang Ma'en Obeidat Brian D Hobbs Tianxiao Huan Hongsheng Gui Margaret M Parker Donglei Hu Lauren S Mogil Gleb Kichaev Jianping Jin Mariaelisa Graff Tamara B Harris Ravi Kalhan Susan R Heckbert Lavinia Paternoster Kristin M Burkart Yongmei Liu Elizabeth G Holliday James G Wilson Judith M Vonk Jason L Sanders R Graham Barr Renée de Mutsert Ana Maria Baptista Menezes Hieab H H Adams Maarten van den Berge Roby Joehanes Albert M Levin Jennifer Liberto Lenore J Launer Alanna C Morrison Colleen M Sitlani Juan C Celedón Stephen B Kritchevsky Rodney J Scott Kaare Christensen Jerome I Rotter Tobias N Bonten Fernando César Wehrmeister Yohan Bossé Shujie Xiao Sam Oh Nora Franceschini Jennifer A Brody Robert C Kaplan Kurt Lohman Mark McEvoy Michael A Province Frits R Rosendaal Kent D Taylor David C Nickle L Keoki Williams Esteban G Burchard Heather E Wheeler Don D Sin Vilmundur Gudnason Kari E North Myriam Fornage Bruce M Psaty Richard H Myers George O'Connor Torben Hansen Cathy C Laurie Patricia A Cassano Joohon Sung Woo Jin Kim John R Attia Leslie Lange H Marike Boezen Bharat Thyagarajan Stephen S Rich Dennis O Mook-Kanamori Bernardo Lessa Horta André G Uitterlinden Hae Kyung Im Michael H Cho Guy G Brusselle Sina A Gharib Josée Dupuis Ani Manichaikul Stephanie J London

Nat Commun 2018 07 30;9(1):2976. Epub 2018 Jul 30.

Epidemiology Branch National Institute of Environmental Health Sciences, National Institutes of Health, US Department of Health and Human Services, Research Triangle Park, NC, 27709, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-018-05369-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065313PMC
July 2018

Asthma and its comorbidities in middle-aged and older adults; the Rotterdam Study.

Respir Med 2018 06 11;139:6-12. Epub 2018 Apr 11.

Department of Respiratory Medicine, Ghent University Hospital, Corneel Heymanslaan 10, 9000 Ghent, Belgium; Department of Epidemiology, Erasmus MC - University Medical Center Rotterdam, PO Box 2040, 3000 CA Rotterdam, The Netherlands; Department of Respiratory Medicine Erasmus MC - University Medical Center Rotterdam, PO Box 2040, 3000 CA Rotterdam, The Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.rmed.2018.04.006DOI Listing
June 2018

DPP4, the Middle East Respiratory Syndrome Coronavirus Receptor, is Upregulated in Lungs of Smokers and Chronic Obstructive Pulmonary Disease Patients.

Clin Infect Dis 2018 01;66(1):45-53

Laboratory for Translational Research in Obstructive Pulmonary Diseases, Department of Respiratory Medicine, Ghent University HospitalGhent, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/cid/cix741DOI Listing
January 2018

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

Authors:
Florence Demenais Patricia Margaritte-Jeannin Kathleen C Barnes William O C Cookson Janine Altmüller Wei Ang R Graham Barr Terri H Beaty Allan B Becker John Beilby Hans Bisgaard Unnur Steina Bjornsdottir Eugene Bleecker Klaus Bønnelykke Dorret I Boomsma Emmanuelle Bouzigon Christopher E Brightling Myriam Brossard Guy G Brusselle Esteban Burchard Kristin M Burkart Andrew Bush Moira Chan-Yeung Kian Fan Chung Alexessander Couto Alves John A Curtin Adnan Custovic Denise Daley Johan C de Jongste Blanca E Del-Rio-Navarro Kathleen M Donohue Liesbeth Duijts Celeste Eng Johan G Eriksson Martin Farrall Yuliya Fedorova Bjarke Feenstra Manuel A Ferreira Maxim B Freidin Zofia Gajdos Jim Gauderman Ulrike Gehring Frank Geller Jon Genuneit Sina A Gharib Frank Gilliland Raquel Granell Penelope E Graves Daniel F Gudbjartsson Tari Haahtela Susan R Heckbert Dick Heederik Joachim Heinrich Markku Heliövaara John Henderson Blanca E Himes Hiroshi Hirose Joel N Hirschhorn Albert Hofman Patrick Holt Jouke Hottenga Thomas J Hudson Jennie Hui Medea Imboden Vladimir Ivanov Vincent W V Jaddoe Alan James Christer Janson Marjo-Riitta Jarvelin Deborah Jarvis Graham Jones Ingileif Jonsdottir Pekka Jousilahti Michael Kabesch Mika Kähönen David B Kantor Alexandra S Karunas Elza Khusnutdinova Gerard H Koppelman Anita L Kozyrskyj Eskil Kreiner Michiaki Kubo Rajesh Kumar Ashish Kumar Mikko Kuokkanen Lies Lahousse Tarja Laitinen Catherine Laprise Mark Lathrop Susanne Lau Young-Ae Lee Terho Lehtimäki Sébastien Letort Albert M Levin Guo Li Liming Liang Laura R Loehr Stephanie J London Daan W Loth Ani Manichaikul Ingo Marenholz Fernando J Martinez Melanie C Matheson Rasika A Mathias Kenji Matsumoto Hamdi Mbarek Wendy L McArdle Mads Melbye Erik Melén Deborah Meyers Sven Michel Hamida Mohamdi Arthur W Musk Rachel A Myers Maartje A E Nieuwenhuis Emiko Noguchi George T O'Connor Ludmila M Ogorodova Cameron D Palmer Aarno Palotie Julie E Park Craig E Pennell Göran Pershagen Alexey Polonikov Dirkje S Postma Nicole Probst-Hensch Valery P Puzyrev Benjamin A Raby Olli T Raitakari Adaikalavan Ramasamy Stephen S Rich Colin F Robertson Isabelle Romieu Muhammad T Salam Veikko Salomaa Vivi Schlünssen Robert Scott Polina A Selivanova Torben Sigsgaard Angela Simpson Valérie Siroux Lewis J Smith Maria Solodilova Marie Standl Kari Stefansson David P Strachan Bruno H Stricker Atsushi Takahashi Philip J Thompson Gudmar Thorleifsson Unnur Thorsteinsdottir Carla M T Tiesler Dara G Torgerson Tatsuhiko Tsunoda André G Uitterlinden Ralf J P van der Valk Amaury Vaysse Sailaja Vedantam Andrea von Berg Erika von Mutius Judith M Vonk Johannes Waage Nick J Wareham Scott T Weiss Wendy B White Magnus Wickman Elisabeth Widén Gonneke Willemsen L Keoki Williams Inge M Wouters James J Yang Jing Hua Zhao Miriam F Moffatt Carole Ober Dan L Nicolae

Nat Genet 2018 01 22;50(1):42-53. Epub 2017 Dec 22.

Departments of Statistics, Human Genetics and Medicine, Section of Genetic Medicine, University of Chicago, Chicago, IL, USA.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/s41588-017-0014-7
Publisher Site
http://dx.doi.org/10.1038/s41588-017-0014-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901974PMC
January 2018

Meta-analysis of exome array data identifies six novel genetic loci for lung function.

Authors:
Victoria E Jackson Jeanne C Latourelle Louise V Wain Albert V Smith Megan L Grove Traci M Bartz Ma'en Obeidat Michael A Province Wei Gao Beenish Qaiser David J Porteous Patricia A Cassano Tarunveer S Ahluwalia Niels Grarup Jin Li Elisabeth Altmaier Jonathan Marten Sarah E Harris Ani Manichaikul Tess D Pottinger Ruifang Li-Gao Allan Lind-Thomsen Anubha Mahajan Lies Lahousse Medea Imboden Alexander Teumer Bram Prins Leo-Pekka Lyytikäinen Gudny Eiriksdottir Nora Franceschini Colleen M Sitlani Jennifer A Brody Yohan Bossé Wim Timens Aldi Kraja Anu Loukola Wenbo Tang Yongmei Liu Jette Bork-Jensen Johanne M Justesen Allan Linneberg Leslie A Lange Rajesh Rawal Stefan Karrasch Jennifer E Huffman Blair H Smith Gail Davies Kristin M Burkart Josyf C Mychaleckyj Tobias N Bonten Stefan Enroth Lars Lind Guy G Brusselle Ashish Kumar Beate Stubbe Mika Kähönen Annah B Wyss Bruce M Psaty Susan R Heckbert Ke Hao Taina Rantanen Stephen B Kritchevsky Kurt Lohman Tea Skaaby Charlotta Pisinger Torben Hansen Holger Schulz Ozren Polasek Archie Campbell John M Starr Stephen S Rich Dennis O Mook-Kanamori Åsa Johansson Erik Ingelsson André G Uitterlinden Stefan Weiss Olli T Raitakari Vilmundur Gudnason Kari E North Sina A Gharib Don D Sin Kent D Taylor George T O'Connor Jaakko Kaprio Tamara B Harris Oluf Pederson Henrik Vestergaard James G Wilson Konstantin Strauch Caroline Hayward Shona Kerr Ian J Deary R Graham Barr Renée de Mutsert Ulf Gyllensten Andrew P Morris M Arfan Ikram Nicole Probst-Hensch Sven Gläser Eleftheria Zeggini Terho Lehtimäki David P Strachan Josée Dupuis Alanna C Morrison Ian P Hall Martin D Tobin Stephanie J London

Wellcome Open Res 2018 12;3. Epub 2018 Jan 12.

Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Dept of Health and Human Services, Research Triangle Park, NC, 27709, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.12688/wellcomeopenres.12583.3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081985PMC
January 2018

Pulmonary function and diffusion capacity are associated with pulmonary arterial systolic pressure in the general population: The Rotterdam Study.

Respir Med 2017 Nov 21;132:50-55. Epub 2017 Sep 21.

Department of Epidemiology, Erasmus MC - University Medical Center Rotterdam, Rotterdam, The Netherlands; Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium; Department of Respiratory Medicine, Erasmus MC - University Medical Center Rotterdam, Rotterdam, The Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.rmed.2017.09.009DOI Listing
November 2017

microRNA profiling in lung tissue and bronchoalveolar lavage of cigarette smoke-exposed mice and in COPD patients: a translational approach.

Sci Rep 2017 10 9;7(1):12871. Epub 2017 Oct 9.

Laboratory for Translational Research in Obstructive Pulmonary Diseases, Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-017-13265-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634489PMC
October 2017

Efficacy of tiotropium-olodaterol fixed-dose combination in COPD.

Int J Chron Obstruct Pulmon Dis 2016 13;11:3163-3177. Epub 2016 Dec 13.

Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2147/COPD.S92840DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167492PMC
August 2017

Reply: Direct Detection of Circulating MicroRNAs Unveiled the Absence of MicroRNA-218-5p in Smoker Subjects.

Am J Respir Crit Care Med 2017 08;196(4):533

1 Ghent University Hospital Ghent, Belgium and.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1164/rccm.201701-0224LEDOI Listing
August 2017

Epidemiology and impact of chronic bronchitis in chronic obstructive pulmonary disease.

Eur Respir J 2017 08 10;50(2). Epub 2017 Aug 10.

Dept of Respiratory Medicine, Ghent University and Ghent University Hospital, Ghent, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1183/13993003.02470-2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593375PMC
August 2017

Sputum Neutrophil Elastase as a Biomarker for Disease Activity in Bronchiectasis.

Am J Respir Crit Care Med 2017 05;195(10):1289-1291

1 Department of Respiratory Medicine Ghent University Hospital Ghent, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1164/rccm.201612-2476EDDOI Listing
May 2017

Development of a Healthy Aging Score in the Population-Based Rotterdam Study: Evaluating Age and Sex Differences.

J Am Med Dir Assoc 2017 Mar 18;18(3):276.e1-276.e7. Epub 2017 Jan 18.

Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jamda.2016.11.021DOI Listing
March 2017

Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis.

Nat Genet 2017 Mar 6;49(3):426-432. Epub 2017 Feb 6.

Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.3752DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381275PMC
March 2017

Sex-Specific Genetic Risk Factors for Chronic Obstructive Pulmonary Disease.

Am J Respir Cell Mol Biol 2017 03;56(3):281-282

1 Department of Respiratory Medicine Ghent University Hospital Ghent, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1165/rcmb.2016-0399EDDOI Listing
March 2017

Association between lutein intake and lung function in adults: the Rotterdam Study.

Br J Nutr 2017 Mar 5;117(5):720-730. Epub 2017 Apr 5.

1Department of Epidemiology,Erasmus MC University Medical Center,3000 CA, Rotterdam,The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/S0007114517000319DOI Listing
March 2017

Genome-wide association study on the FEV/FVC ratio in never-smokers identifies HHIP and FAM13A.

J Allergy Clin Immunol 2017 02 6;139(2):533-540. Epub 2016 Sep 6.

Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands; Groningen Research Institute for Asthma and COPD (GRIAC), University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaci.2016.06.062DOI Listing
February 2017

Dysregulation of type 2 innate lymphoid cells and T2 cells impairs pollutant-induced allergic airway responses.

J Allergy Clin Immunol 2017 01 11;139(1):246-257.e4. Epub 2016 May 11.

Department of Respiratory Medicine, Laboratory for Translational Research in Obstructive Pulmonary Diseases, Ghent University Hospital, Ghent, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaci.2016.03.044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5420012PMC
January 2017

MicroRNA Profiling Reveals a Role for MicroRNA-218-5p in the Pathogenesis of Chronic Obstructive Pulmonary Disease.

Am J Respir Crit Care Med 2017 01;195(1):43-56

1 Laboratory for Translational Research in Obstructive Pulmonary Diseases, Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1164/rccm.201506-1182OCDOI Listing
January 2017

Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD.

J Exp Med 2017 01 15;214(1):143-163. Epub 2016 Dec 15.

Comprehensive Pneumology Center, Research Unit Lung Repair and Regeneration, Helmholtz Center Munich, Ludwig Maximilians University Munich, University Hospital Grosshadern, 81377 Munich, Germany

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1084/jem.20160675DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5206496PMC
January 2017

AZALEA Trial Highlights Antibiotic Overuse in Acute Asthma Attacks.

JAMA Intern Med 2016 11;176(11):1637-1638

Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jamainternmed.2016.6046DOI Listing
November 2016

Chronic obstructive pulmonary disease and sudden cardiac death: A systematic review.

Trends Cardiovasc Med 2016 10 9;26(7):606-13. Epub 2016 Apr 9.

Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands; Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tcm.2016.04.001DOI Listing
October 2016

Prostaglandin D2 receptor antagonism: a novel therapeutic option for eosinophilic asthma?

Lancet Respir Med 2016 09 5;4(9):676-677. Epub 2016 Aug 5.

Department of Respiratory Medicine, Ghent University Hospital, B-9000 Ghent, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S2213-2600(16)30201-6DOI Listing
September 2016

The ever-expanding ERS fellowship programmes: achievements over the past 3 years.

Eur Respir J 2016 09;48(3):595-9

Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton General Hospital, Southampton, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1183/13993003.01146-2016DOI Listing
September 2016

Using a bronchial airway gene expression classifier.

Lancet Respir Med 2016 09;4(9):694

Department of Respiratory Medicine, Ghent University Hospital, De Pintelaan 185, B-9000 Ghent, BELGIUM; Departments of Epidemiology and Respiratory Medicine, Erasmus Medical Center, CA Rotterdam, Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S2213-2600(16)30239-9DOI Listing
September 2016

Prevalence and incidence of COPD in smokers and non-smokers: the Rotterdam Study.

Eur J Epidemiol 2016 08 5;31(8):785-92. Epub 2016 Mar 5.

Department of Respiratory Medicine, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10654-016-0132-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005388PMC
August 2016

Characterization and Quantification of Innate Lymphoid Cell Subsets in Human Lung.

PLoS One 2016 4;11(1):e0145961. Epub 2016 Jan 4.

Department of Respiratory Medicine, Laboratory for Translational Research in Obstructive Pulmonary Diseases, Ghent University Hospital, Ghent, Belgium.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0145961PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699688PMC
July 2016

Chronic cigarette smoke exposure induces microbial and inflammatory shifts and mucin changes in the murine gut.

Environ Microbiol 2016 05 22;18(5):1352-63. Epub 2015 Jul 22.

Laboratory of Microbial Ecology and Technology (LabMET), Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/1462-2920.12934DOI Listing
May 2016

Risk of Frailty in Elderly With COPD: A Population-Based Study.

J Gerontol A Biol Sci Med Sci 2016 May 9;71(5):689-95. Epub 2015 Sep 9.

Departments of Epidemiology, Netherlands Consortium on Healthy Aging (NCHA), Leiden, The Netherlands. Inspectorate of Healthcare, The Hague, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/gerona/glv154DOI Listing
May 2016

Airway Surface Dehydration Aggravates Cigarette Smoke-Induced Hallmarks of COPD in Mice.

PLoS One 2015 12;10(6):e0129897. Epub 2015 Jun 12.

Laboratory for Translational Research in Obstructive Pulmonary Diseases, Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0129897PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466573PMC
April 2016

Pro- and Anti-Inflammatory Role of ChemR23 Signaling in Pollutant-Induced Inflammatory Lung Responses.

J Immunol 2016 Feb 15;196(4):1882-90. Epub 2016 Jan 15.

Laboratory for Translational Research in Obstructive Pulmonary Diseases, Department of Respiratory Medicine, Ghent University Hospital, 9000 Ghent, Belgium; and.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1501113DOI Listing
February 2016

Cardiac effects of current treatments of chronic obstructive pulmonary disease.

Lancet Respir Med 2016 Feb 12;4(2):149-64. Epub 2016 Jan 12.

Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium; Department of Epidemiology, Erasmus Medical Center, Rotterdam, Netherlands; Department of Respiratory Medicine, Erasmus Medical Center, Rotterdam, Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S2213-2600(15)00518-4DOI Listing
February 2016

Understanding age-related diseases: report of the 2015 Ageing Summit.

Eur Respir J 2016 Jan;47(1):5-9

Dept of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium Erasmus Medical Center, Dept of Epidemiology, CA Rotterdam, The Netherlands Dept of Respiratory Medicine, Erasmus Medical Center, CA Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1183/13993003.00837-2015DOI Listing
January 2016

Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function.

PLoS One 2014 1;9(7):e100776. Epub 2014 Jul 1.

Division of Nutritional Sciences, Cornell University, Ithaca, New York, United States of America; Department of Health Care Policy and Research, Division of Biostatistics and Epidemiology, Weill Cornell Medical College, New York, New York, United States of America.

View Article

Download full-text PDF

Source
http://repub.eur.nl/pub/55346/journal.pone.0100776.pdf
Web Search
http://dx.plos.org/10.1371/journal.pone.0100776
Publisher Site
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0100776PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077649PMC
November 2015

Chronic obstructive pulmonary disease and cerebrovascular disease: A comprehensive review.

Respir Med 2015 Nov 26;109(11):1371-80. Epub 2015 Jul 26.

Department of Respiratory Medicine, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium; Department of Epidemiology, Erasmus Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands; Department of Respiratory Medicine, Erasmus Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.rmed.2015.07.014DOI Listing
November 2015

MicroRNA miR-22 drives T(H)17 responses in emphysema.

Nat Immunol 2015 Nov;16(11):1109-10

Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ni.3295DOI Listing
November 2015

The Rotterdam study: why fall in COPD?

Eur Respir J 2015 Nov;46(5):1530-1

Dept of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium Dept of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands Dept of Respiratory Medicine, Erasmus Medical Center, Rotterdam, the Netherlands.

View Article

Download full-text PDF

Source
http://erj.ersjournals.com/lookup/doi/10.1183/13993003.01332
Publisher Site
http://dx.doi.org/10.1183/13993003.01332-2015DOI Listing
November 2015

Elucidating COPD pathogenesis by large-scale genetic analyses.

Lancet Respir Med 2015 Oct 27;3(10):737-9. Epub 2015 Sep 27.

Department of Respiratory Medicine, Ghent University Hospital, 9000 Ghent, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S2213-2600(15)00360-4DOI Listing
October 2015

Role of B Cell-Activating Factor in Chronic Obstructive Pulmonary Disease.

Am J Respir Crit Care Med 2015 Sep;192(6):706-18

1 Laboratory for Translational Research in Obstructive Pulmonary Diseases, Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1164/rccm.201501-0103OCDOI Listing
September 2015

Non-coding RNAs in the pathogenesis of COPD.

Thorax 2015 Aug 20;70(8):782-91. Epub 2015 May 20.

Laboratory for Translational Research in Obstructive Pulmonary Diseases, Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/thoraxjnl-2014-206560DOI Listing
August 2015

Gait patterns in COPD: the Rotterdam Study.

Eur Respir J 2015 Jul 19;46(1):88-95. Epub 2015 Feb 19.

Dept of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands Dept of Radiology, Erasmus Medical Center, Rotterdam, The Netherlands Dept of Neuroscience, Erasmus Medical Center, Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://erj.ersjournals.com/lookup/doi/10.1183/09031936.00213
Publisher Site
http://dx.doi.org/10.1183/09031936.00213214DOI Listing
July 2015

Chronic obstructive pulmonary disease and sudden cardiac death: the Rotterdam study.

Eur Heart J 2015 Jul 28;36(27):1754-61. Epub 2015 Apr 28.

Department of Respiratory Medicine, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium Department of Epidemiology, Erasmus Medical Center, PO Box 2040, Rotterdam 3000 CA, The Netherlands Department of Respiratory Medicine, Erasmus Medical Center, PO Box 2040, Rotterdam 3000 CA, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/eurheartj/ehv121DOI Listing
July 2015

Transforming growth factor-β superfamily in obstructive lung diseases. more suspects than TGF-β alone.

Am J Respir Cell Mol Biol 2015 Jun;52(6):653-62

Laboratory for Translational Research in Obstructive Pulmonary Diseases, Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1165/rcmb.2014-0282RTDOI Listing
June 2015

Targeted therapy with inhaled corticosteroids in COPD according to blood eosinophil counts.

Lancet Respir Med 2015 Jun 16;3(6):416-7. Epub 2015 Apr 16.

Department of Respiratory Medicine, Ghent University Hospital, 9000 Ghent, Belgium; Department of Epidemiology, Erasmus Medical Center, 3000 CA Rotterdam, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S2213-2600(15)00145-9DOI Listing
June 2015

Are the antimicrobial properties of macrolides required for their therapeutic efficacy in chronic neutrophilic airway diseases?

Authors:
Guy G Brusselle

Thorax 2015 May;70(5):401-3

Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium Department of Epidemiology and Respiratory Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/thoraxjnl-2015-207080DOI Listing
May 2015

Risk of a biased assessment of the evidence when limiting literature searches to the English language: macrolides in asthma as an illustrative example.

Pulm Pharmacol Ther 2015 Apr 28;31:109-10. Epub 2014 Sep 28.

Department of Pathophysiology and Transplantation, Università degli Studi di Milano, IRCCS Fondazione Ospedale Maggiore Policlinico Cà Granda Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pupt.2014.09.006DOI Listing
April 2015

ERS guidelines, statements and technical standards published in the ERJ in 2014: a year in review.

Eur Respir J 2015 Apr;45(4):863-6

7th Respiratory Medicine Dept and Asthma Centre, Athens Chest Hospital "Sotiria", Athens, Greece.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1183/09031936.00238514DOI Listing
April 2015

Role of the nitric oxide-soluble guanylyl cyclase pathway in obstructive airway diseases.

Pulm Pharmacol Ther 2014 Oct 17;29(1):1-6. Epub 2014 Jul 17.

Laboratory for Translational Research in Obstructive Pulmonary Diseases, Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pupt.2014.07.004DOI Listing
October 2014

Mepolizumab treatment in patients with severe eosinophilic asthma.

N Engl J Med 2014 Sep 8;371(13):1198-207. Epub 2014 Sep 8.

From the Respiratory Therapeutic Area Unit, GlaxoSmithKline, Research Triangle Park, NC (H.G.O., L.E.K., S.W.Y.); Johns Hopkins Asthma and Allergy Center, Baltimore (M.C.L.); Respiratory Medicine Unit, Nuffield Department of Medicine, University of Oxford, Oxford (I.D.P.), and Clinical Statistics, GlaxoSmithKline, Stockley Park, Middlesex (O.N.K.) - both in the United Kingdom; the Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium (G.G.B.); the Lung Centre, Institute for Heart and Lung Health, Vancouver, BC, Canada (J.M.F.); the Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy (A.C.); and Assistance Publique-Hôpitaux de Paris, Département Hospitalo-Universitaire Thorax Innovation, Service de Pneumologie, Hôpital Bicêtre, Université Paris-Sud, and INSERM Unité Mixte de Recherche 999, Le Kremlin-Bicêtre (M.H.), and Unités Mixtes de Recherche INSERM Unité 1067 Centre Nationale de la Recherche Scientifique 7733, Aix-Marseille Université, Department of Respiratory Diseases and Clinical Investigation Center, Assistance Publique-Hôpitaux de Marseille, Hôpital Nord, Marseille (P.C.) - both in France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMoa1403290DOI Listing
September 2014

Genome-wide association analysis identifies six new loci associated with forced vital capacity.

Authors:
Daan W Loth María Soler Artigas Sina A Gharib Louise V Wain Nora Franceschini Beate Koch Tess D Pottinger Albert Vernon Smith Qing Duan Chris Oldmeadow Mi Kyeong Lee David P Strachan Alan L James Jennifer E Huffman Veronique Vitart Adaikalavan Ramasamy Nicholas J Wareham Jaakko Kaprio Xin-Qun Wang Holly Trochet Mika Kähönen Claudia Flexeder Eva Albrecht Lorna M Lopez Kim de Jong Bharat Thyagarajan Alexessander Couto Alves Stefan Enroth Ernst Omenaas Peter K Joshi Tove Fall Ana Viñuela Lenore J Launer Laura R Loehr Myriam Fornage Guo Li Jemma B Wilk Wenbo Tang Ani Manichaikul Lies Lahousse Tamara B Harris Kari E North Alicja R Rudnicka Jennie Hui Xiangjun Gu Thomas Lumley Alan F Wright Nicholas D Hastie Susan Campbell Rajesh Kumar Isabelle Pin Robert A Scott Kirsi H Pietiläinen Ida Surakka Yongmei Liu Elizabeth G Holliday Holger Schulz Joachim Heinrich Gail Davies Judith M Vonk Mary Wojczynski Anneli Pouta Asa Johansson Sarah H Wild Erik Ingelsson Fernando Rivadeneira Henry Völzke Pirro G Hysi Gudny Eiriksdottir Alanna C Morrison Jerome I Rotter Wei Gao Dirkje S Postma Wendy B White Stephen S Rich Albert Hofman Thor Aspelund David Couper Lewis J Smith Bruce M Psaty Kurt Lohman Esteban G Burchard André G Uitterlinden Melissa Garcia Bonnie R Joubert Wendy L McArdle A Bill Musk Nadia Hansel Susan R Heckbert Lina Zgaga Joyce B J van Meurs Pau Navarro Igor Rudan Yeon-Mok Oh Susan Redline Deborah L Jarvis Jing Hua Zhao Taina Rantanen George T O'Connor Samuli Ripatti Rodney J Scott Stefan Karrasch Harald Grallert Nathan C Gaddis John M Starr Cisca Wijmenga Ryan L Minster David J Lederer Juha Pekkanen Ulf Gyllensten Harry Campbell Andrew P Morris Sven Gläser Christopher J Hammond Kristin M Burkart John Beilby Stephen B Kritchevsky Vilmundur Gudnason Dana B Hancock O Dale Williams Ozren Polasek Tatijana Zemunik Ivana Kolcic Marcy F Petrini Matthias Wjst Woo Jin Kim David J Porteous Generation Scotland Blair H Smith Anne Viljanen Markku Heliövaara John R Attia Ian Sayers Regina Hampel Christian Gieger Ian J Deary H Marike Boezen Anne Newman Marjo-Riitta Jarvelin James F Wilson Lars Lind Bruno H Stricker Alexander Teumer Timothy D Spector Erik Melén Marjolein J Peters Leslie A Lange R Graham Barr Ken R Bracke Fien M Verhamme Joohon Sung Pieter S Hiemstra Patricia A Cassano Akshay Sood Caroline Hayward Josée Dupuis Ian P Hall Guy G Brusselle Martin D Tobin Stephanie J London

Nat Genet 2014 Jul 15;46(7):669-77. Epub 2014 Jun 15.

1] Epidemiology Branch, National Institute of Environmental Health Sciences, US National Institutes of Health, US Department of Health and Human Services, Research Triangle Park, North Carolina, USA. [2].

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.3011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140093PMC
July 2014

Use of tiotropium Respimat versus HandiHaler and mortality in patients with COPD.

Eur Respir J 2014 Jun;43(6):1818-9

Ghent University Hospital, Dept of Respiratory Medicine, Ghent, Belgium Erasmus Medical Center, Dept of Epidemiology, Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1183/09031936.00036314DOI Listing
June 2014

Adverse outcomes of frailty in the elderly: the Rotterdam Study.

Eur J Epidemiol 2014 Jun 17;29(6):419-27. Epub 2014 Jun 17.

Department of Respiratory Medicine, Ghent University Hospital, Ghent University, De Pintelaan 185, 9000, Ghent, Belgium,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10654-014-9924-1DOI Listing
June 2014

Bone mineral density and chronic lung disease mortality: the rotterdam study.

J Clin Endocrinol Metab 2014 May 25;99(5):1834-42. Epub 2014 Feb 25.

Departments of Internal Medicine (N.C.-O., M.C.C.-B., L.O., B.H.C.S., H.T., F.R., A.G.U., M.C.Z.) and Epidemiology (M.C.C.-B., O.H.F., B.H.C.S., G.G.B., L.L., A.H., F.R., A.G.U., M.C.Z.), Erasmus MC, 3000 CA Rotterdam, The Netherlands; Department of Respiratory Medicine (G.G.B., L.L.), Ghent University Hospital, B-9000 Ghent, Belgium; Departments of Respiratory Medicine (G.G.B.) and Psychiatric Epidemiology (H.T.), Erasmus MC, 3000 CA Rotterdam, The Netherlands; and Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Ageing (M.C.C.-B., L.O., O.H.F., A.H., F.R., A.G.U., M.C.Z.), 2300 RC Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/jc.2013-3819DOI Listing
May 2014

Inflammasomes in respiratory disease: from bench to bedside.

Chest 2014 May;145(5):1121-1133

Laboratory for Translational Research of Obstructive Pulmonary Disease, Ghent University Hospital, Ghent, Belgium; Departments of Epidemiology and Respiratory Medicine, Erasmus MC, Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1378/chest.13-1885DOI Listing
May 2014

Usage of inhalation devices in asthma and chronic obstructive pulmonary disease: a Delphi consensus statement.

Expert Opin Drug Deliv 2014 Mar 18;11(3):313-23. Epub 2013 Dec 18.

Centre Hospitalier Universitaire Saint-Pierre, Department of Pneumology , Rue Haute, 322, B-1000 Brussels , Belgium +32 02 535 42 03 ; +32 02 535 33 62 ;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1517/17425247.2014.872626DOI Listing
March 2014

Mechanistic links between COPD and lung cancer: a role of microRNA let‑7?

Nat Rev Cancer 2014 Jan;14(1):70

View Article

Download full-text PDF

Source
January 2014