Publications by authors named "Guy Brusselle"

100Publications

Increased expression of ACE2, the SARS-CoV-2 entry receptor, in alveolar and bronchial epithelium of smokers and COPD subjects.

Eur Respir J 2020 08 20;56(2). Epub 2020 Aug 20.

Laboratory for Translational Research in Obstructive Pulmonary Diseases, Dept of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium

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http://dx.doi.org/10.1183/13993003.02378-2020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7366177PMC
August 2020

Reply to Lipworth : Inhaled Corticosteroids and COVID-19.

Am J Respir Crit Care Med 2020 09;202(6):900-902

Ghent University Hospital Gent, Belgium and.

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http://dx.doi.org/10.1164/rccm.202006-2129LEDOI Listing
September 2020

A new once-daily long-acting β-adrenoceptor agonist-inhaled corticosteroid combination therapy for asthma.

Authors:
Guy Brusselle

Lancet Respir Med 2020 Jul 9. Epub 2020 Jul 9.

Department of Respiratory Medicine, Ghent University Hospital, 9000 Ghent, Belgium. Electronic address:

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http://dx.doi.org/10.1016/S2213-2600(20)30305-2DOI Listing
July 2020

Treatment options in type-2 low asthma.

Eur Respir J 2020 Jun 25. Epub 2020 Jun 25.

Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium.

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http://dx.doi.org/10.1183/13993003.00528-2020DOI Listing
June 2020

ARIA digital anamorphosis: Digital transformation of health and care in airway diseases from research to practice.

Authors:
Jean Bousquet Josep M Anto Claus Bachert Tari Haahtela Torsten Zuberbier Wienczyslawa Czarlewski Anna Bedbrook Sinthia Bosnic-Anticevich G Walter Canonica Victoria Cardona ElisioCosta Alvaro A Cruz Marina Erhola Wytske J Fokkens Joao A Fonseca Maddalena Illario Juan CarlosIvancevich Marek Jutel Ludger Klimek PiotrKuna Violeta Kvedariene Ltt Le Desiree Larenas-Linnemann Daniel Laune Olga M Lourenço Eric Melén Joaquim Mullol Marek Niedoszytko Mikaëla Odemyr Yoshitaka Okamoto Nikos G Papadopoulos Vincenzo Patella Oliver Pfaar Nhân Pham-Thi Christine Rolland Boleslaw Samolinski Aziz Sheikh Mikhail Sofiev Charlotte SuppliUlrik Ana Todo-Bom Peter V Tomazic Sanna Toppila-Salmi Ioanna Tsiligianni Arunas Valiulis Erkka Valovirta Maria-Teresa Ventura Samantha Walker Sian Williams Arzu Yorgancioglu Ioana Agache Cezmi A Akdis Rute Almeida Ignacio J Ansotegui Isabella Annesi-Maesano Sylvie Arnavielhe Xavier Basagaña Eric Bateman Annabelle Bédard Martin Bedolla-Barajas Sven Becker Kazi S Bennoor Samuel Benveniste Karl C Bergmann Michael Bewick Slawomir Bialek Nils Billo Carsten Bindslev-Jensen Leif Bjermer Hubert Blain Matteo Bonini Philippe Bonniaud Isabelle Bosse Jacques Bouchard Louis P Boulet Rodolphe Bourret Koen Boussery Fluvio Braido Vitalis Briedis Andrew Briggs Christopher E Brightling JanBrozek Guy Brusselle Luisa Brussino Roland Buhl Roland Buonaiuto Moises A Calderon Paolo Camargos Thierry Camuzat Luis Caraballo Ana Maria Carriazo Warner Carr Christine Cartier Thomas Casale Lorenzo Cecchi Alfonso M Cepeda Sarabia Niels Chavannes Ekaterine Chkhartishvili Derek K Chu Cemal Cingi Jaime Correia de Sousa David J Costa Anne Lise Courbis Adnan Custovic Biljana Cvetkosvki Gennaro D'Amato Jane da Silva Carina Dantas Dejan Dokic Yves Dauvilliers Giulia De Feo Govert De Vries Philippe Devillier Stefania Di Capua Gerard Dray Ruta Dubakiene Stephen R Durham Marc Dykewicz Motohiro Ebisawa Mina Gaga Yehia El-Gamal Enrico Heffler Regina Emuzyte John Farrell Jean-Luc Fauquert Alessandro Fiocchi Antje Fink-Wagner Jean-François Fontaine José M Fuentes Perez Bilun Gemicioğlu Amiran Gamkrelidze Judith Garcia-Aymerich Philippe Gevaert Maximiliano Gomez Sandra González Diaz Maia Gotua Nick A Guldemond Maria-Antonieta Guzmán Jawad Hajjam Yunuen R Huerta Villalobos Marc Humbert Guido Iaccarino Despo Ierodiakonou TomohisaIinuma Ewa Jassem Guy Joos Ki-Suck Jung Igor Kaidashev Omer Kalayci Przemyslaw Kardas Thomas Keil Musa Khaitov Nikolai Khaltaev Jorg Kleine-Tebbe Rostislav Kouznetsov Marek L Kowalski Vicky Kritikos Inger Kull Stefania La Grutta Lisa Leonardini Henrik Ljungberg Philip Lieberman Brian Lipworth Karin C Lodrup Carlsen Catarina Lopes-Pereira Claudia C Loureiro Renaud Louis Alpana Mair Bassam Mahboub Michaël Makris Joao Malva Patrick Manning Gailen D Marshall Mohamed R Masjedi Jorge F Maspero Pedro Carreiro-Martins Mika Makela Eve Mathieu-Dupas Marcus Maurer Esteban De Manuel Keenoy Elisabete Melo-Gomes Eli O Meltzer Enrica Menditto Jacques Mercier Yann Micheli Neven Miculinic Florin Mihaltan Branislava Milenkovic DimitiriosI Mitsias Giuliana Moda Maria-Dolores Mogica-Martinez Yousser Mohammad Steve Montefort Ricardo Monti Mario Morais-Almeida Ralph Mösges Lars Münter Antonella Muraro Ruth Murray Robert Naclerio Luigi Napoli Leila Namazova-Baranova Hugo Neffen Kristoff Nekam Angelo Neou Björn Nordlund Ettore Novellino Dieudonné Nyembue Robin O'Hehir Ken Ohta Kimi Okubo Gabrielle L Onorato Solange Ouedraogo Julia Palamarchuk Isabella Pali-Schöll Peter Panzner Hae-Sim Park Gianni Passalacqua Jean-Louis Pépin Ema Paulino Jim Phillips Robert Picard Hilary Pinnock Davor Plavec Todor A Popov Fabienne Portejoie David Price Emmanuel P Prokopakis Fotis Psarros Benoit Pugin Francesca Puggioni Pablo Quinones-Delgado Filip Raciborski Rojin Rajabian-Söderlund Frederico S Regateiro Sietze Reitsma Daniele Rivero-Yeverino Graham Roberts Nicolas Roche Erendira Rodriguez-Zagal Christine Rolland Regina E Roller-Wirnsberger Nelson Rosario Antonino Romano Menahem Rottem Dermot Ryan Johanna Salimäki Mario M Sanchez-Borges Joaquin Sastre Glenis K Scadding Sophie Scheire Peter Schmid-Grendelmeier Holger J Schünemann FaradibaSarquis Serpa Mohamed Shamji Juan-Carlos Sisul Mikhail Sofiev Dirceu Solé David Somekh Talant Sooronbaev Milan Sova François Spertini Otto Spranger Cristiana Stellato Rafael Stelmach Michel Thibaudon Teresa To MondherToumi Omar Usmani AntonioA Valero Rudolph Valenta Marylin Valentin-Rostan Rianne van der Kleij Michiel Van Eerd Olivier Vandenplas Tuula Vasankari Antonio Vaz Carneiro Giorgio Vezzani Frédéric Viart Giovanni Viegi Dana Wallace Martin Wagenmann De Yun Wang Susan Waserman Magnus Wickman Dennis M Williams Gary Wong Piotr Wroczynski Panayiotis K Yiallouros Osman M Yusuf Heather J Zar Stéphane Zeng Mario E Zernotti Luo Zhang Nan Shan Zhong Mihaela Zidarn

Allergy 2020 Jun 8. Epub 2020 Jun 8.

University Clinic of Respiratory and Allergic Diseases, Golnik, Slovenia.

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http://dx.doi.org/10.1111/all.14422DOI Listing
June 2020

Innate lymphoid cells in isocyanate-induced asthma: role of microRNA-155.

Eur Respir J 2020 Sep 24;56(3). Epub 2020 Sep 24.

Dept of Respiratory Medicine, Laboratory for Translational Research in Obstructive Pulmonary Diseases, Ghent University Hospital, Ghent, Belgium

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http://dx.doi.org/10.1183/13993003.01289-2019DOI Listing
September 2020

Expanding the spectrum of European Respiratory Society official scientific documents: short documents complement clinical practice guidelines, statements and technical standards.

Eur Respir J 2020 Jun 4;55(6). Epub 2020 Jun 4.

Institute for Lung Health, NIHR Leicester Biomedical Research Centre, Dept of Respiratory Sciences, University of Leicester, Leicester, UK.

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http://dx.doi.org/10.1183/13993003.01030-2020DOI Listing
June 2020

as a biomarker guide for inhaled corticosteroid step down in patients with mild-to-moderate well-controlled asthma.

Eur Respir J 2020 May 21;55(5). Epub 2020 May 21.

Dept of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium.

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http://dx.doi.org/10.1183/13993003.01319-2020DOI Listing
May 2020

COVID-19, Asthma, and Inhaled Corticosteroids: Another Beneficial Effect of Inhaled Corticosteroids?

Am J Respir Crit Care Med 2020 07;202(1):8-10

Department of Respiratory MedicineGhent University HospitalGent, Belgiumand.

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http://dx.doi.org/10.1164/rccm.202005-1651EDDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328335PMC
July 2020

The global significance of PRISm: how data from low- and middle-income countries link physiology to inflammation.

Eur Respir J 2020 Apr 9;55(4). Epub 2020 Apr 9.

Dept of Respiratory Diseases, Ghent University Hospital, Ghent, Belgium

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http://dx.doi.org/10.1183/13993003.00354-2020DOI Listing
April 2020

GINA fosters World Asthma Day 2020 to prevent asthma deaths.

Am J Physiol Lung Cell Mol Physiol 2020 May 19;318(5):L998-L1000. Epub 2020 Mar 19.

Member of GINA Board of Directors and GINA Science Committee; Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium.

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http://dx.doi.org/10.1152/ajplung.00075.2020DOI Listing
May 2020

Change in blood eosinophils following treatment with inhaled corticosteroids may predict long-term clinical response in COPD.

Eur Respir J 2020 May 27;55(5). Epub 2020 May 27.

Division of Infection, Immunity and Respiratory Medicine, School of Biological Sciences, The University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1183/13993003.02119-2019DOI Listing
May 2020

Severe eosinophilic asthma with nasal polyposis: A phenotype for improved sinonasal and asthma outcomes with mepolizumab therapy.

J Allergy Clin Immunol 2020 Jun 19;145(6):1713-1715. Epub 2020 Feb 19.

Upper Airways Research Laboratory, University Hospital Ghent, Ghent, Belgium.

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http://dx.doi.org/10.1016/j.jaci.2020.02.002DOI Listing
June 2020

DNA methylation is associated with lung function in never smokers.

Respir Res 2019 Dec 2;20(1):268. Epub 2019 Dec 2.

University of Groningen, University Medical Center Groningen, Department of Epidemiology, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands.

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http://dx.doi.org/10.1186/s12931-019-1222-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889726PMC
December 2019

Real-life effectiveness of omalizumab in difficult-to-treat severe asthma: a national cohort study in Belgium.

ERJ Open Res 2019 Oct 25;5(4). Epub 2019 Nov 25.

Dept of Pharmaceutical Policy, National Institute for Health and Disability Insurance, Brussels, Belgium.

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http://dx.doi.org/10.1183/23120541.00253-2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876130PMC
October 2019

Simultaneous inhibition of thymic stromal lymphopoietin, IL-33 and IL-25: A therapeutic option in asthma?

Respirology 2020 Jun 25;25(6):566-567. Epub 2019 Nov 25.

Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium.

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http://dx.doi.org/10.1111/resp.13748DOI Listing
June 2020

Sarcopenia in COPD: a systematic review and meta-analysis.

Eur Respir Rev 2019 Dec 13;28(154). Epub 2019 Nov 13.

Dept of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1183/16000617.0049-2019DOI Listing
December 2019

Atherosclerotic calcification in major vessel beds in chronic obstructive pulmonary disease: The Rotterdam Study.

Atherosclerosis 2019 12 24;291:107-113. Epub 2019 Oct 24.

Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands; Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium; Department of Respiratory Medicine, Erasmus MC, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1016/j.atherosclerosis.2019.10.014DOI Listing
December 2019

Recent advances in chronic obstructive pulmonary disease pathogenesis: from disease mechanisms to precision medicine.

J Pathol 2020 04 3;250(5):624-635. Epub 2019 Dec 3.

University of Groningen, University Medical Center Groningen, Department of Pathology and Medical Biology, Groningen, The Netherlands.

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http://dx.doi.org/10.1002/path.5364DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216938PMC
April 2020

β-Adrenergic Receptor Gene Polymorphisms and Risk of COPD Exacerbations: The Rotterdam Study.

J Clin Med 2019 Nov 1;8(11). Epub 2019 Nov 1.

Department of Medical Informatics, Erasmus University Medical Center, Doctor Molewaterplein 40, 3015 GD Rotterdam, The Netherlands.

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http://dx.doi.org/10.3390/jcm8111835DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912270PMC
November 2019

Next-generation care pathways for allergic rhinitis and asthma multimorbidity: a model for multimorbid non-communicable diseases-Meeting Report (Part 2).

J Thorac Dis 2019 Sep;11(9):4072-4084

Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Uniersität zu Berlin and Berlin Institute of Health, Comprehensive Allergy-Centre, Department of Dermatology and Allergy, Member of GA2LEN, Berlin, Germany.

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http://dx.doi.org/10.21037/jtd.2019.09.38DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6790426PMC
September 2019

Next-generation Allergic Rhinitis and Its Impact on Asthma (ARIA) guidelines for allergic rhinitis based on Grading of Recommendations Assessment, Development and Evaluation (GRADE) and real-world evidence.

Authors:
Jean Bousquet Holger J Schünemann Akdis Togias Claus Bachert Martina Erhola Peter W Hellings Ludger Klimek Oliver Pfaar Dana Wallace Ignacio Ansotegui Ioana Agache Anna Bedbrook Karl-Christian Bergmann Mike Bewick Philippe Bonniaud Sinthia Bosnic-Anticevich Isabelle Bossé Jacques Bouchard Louis-Philippe Boulet Jan Brozek Guy Brusselle Moises A Calderon Walter G Canonica Luis Caraballo Vicky Cardona Thomas Casale Lorenzo Cecchi Derek K Chu Elisio M Costa Alvaro A Cruz Wienczyslawa Czarlewski Gennaro D'Amato Philippe Devillier Mark Dykewicz Motohiro Ebisawa Jean-Louis Fauquert Wytske J Fokkens Joao A Fonseca Jean-François Fontaine Bilun Gemicioglu Roy Gerth van Wijk Tari Haahtela Susanne Halken Despo Ierodiakonou Tomohisa Iinuma Juan-Carlos Ivancevich Marek Jutel Igor Kaidashev Musa Khaitov Omer Kalayci Jorg Kleine Tebbe Marek L Kowalski Piotr Kuna Violeta Kvedariene Stefania La Grutta Désirée Larenas-Linnemann Susanne Lau Daniel Laune Lan Le Philipp Lieberman Karin C Lodrup Carlsen Olga Lourenço Gert Marien Pedro Carreiro-Martins Erik Melén Enrica Menditto Hugo Neffen Gregoire Mercier Ralph Mosgues Joaquim Mullol Antonella Muraro Leyla Namazova Ettore Novellino Robyn O'Hehir Yoshitaka Okamoto Ken Ohta Hae Sim Park Petr Panzner Giovanni Passalacqua Nhan Pham-Thi David Price Graham Roberts Nicolas Roche Christine Rolland Nelson Rosario Dermot Ryan Boleslaw Samolinski Mario Sanchez-Borges Glenis K Scadding Mohamed H Shamji Aziz Sheikh Ana-Maria Todo Bom Sanna Toppila-Salmi Ioana Tsiligianni Marylin Valentin-Rostan Arunas Valiulis Erkka Valovirta Maria-Teresa Ventura Samantha Walker Susan Waserman Arzu Yorgancioglu Torsten Zuberbier

J Allergy Clin Immunol 2020 01 15;145(1):70-80.e3. Epub 2019 Oct 15.

Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Uniersität zu Berlin and Berlin Institute of Health, Comprehensive Allergy-Centre, Department of Dermatology and Allergy, member of GA(2)LEN, Berlin, Germany.

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http://dx.doi.org/10.1016/j.jaci.2019.06.049DOI Listing
January 2020

Trajectory and mortality of preserved ratio impaired spirometry: the Rotterdam Study.

Eur Respir J 2020 01 2;55(1). Epub 2020 Jan 2.

Dept of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium

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http://dx.doi.org/10.1183/13993003.01217-2019DOI Listing
January 2020

Next-generation care pathways for allergic rhinitis and asthma multimorbidity: a model for multimorbid non-communicable diseases-Meeting Report (Part 1).

J Thorac Dis 2019 Aug;11(8):3633-3642

Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Uniersität zu Berlin and Berlin Institute of Health, Comprehensive Allergy-Centre, Department of Dermatology and Allergy, Member of GA2LEN, Berlin, Germany.

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http://dx.doi.org/10.21037/jtd.2019.08.64DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753463PMC
August 2019

Next-generation ARIA care pathways for rhinitis and asthma: a model for multimorbid chronic diseases.

Authors:
J Jean Bousquet Holger J Schünemann Alkis Togias Marina Erhola Peter W Hellings Torsten Zuberbier Ioana Agache Ignacio J Ansotegui Josep M Anto Claus Bachert Sven Becker Martin Bedolla-Barajas Michael Bewick Sinthia Bosnic-Anticevich Isabelle Bosse Louis P Boulet Jean Marc Bourrez Guy Brusselle Niels Chavannes Elisio Costa Alvaro A Cruz Wienczyslawa Czarlewski Wytske J Fokkens Joao A Fonseca Mina Gaga Tari Haahtela Maddalena Illario Ludger Klimek Piotr Kuna Violeta Kvedariene L T T Le Desiree Larenas-Linnemann Daniel Laune Olga M Lourenço Enrica Menditto Joaquin Mullol Yashitaka Okamoto Nikos Papadopoulos Nhân Pham-Thi Robert Picard Hilary Pinnock Nicolas Roche Regina E Roller-Wirnsberger Christine Rolland Boleslaw Samolinski Aziz Sheikh Sanna Toppila-Salmi Ioanna Tsiligianni Arunas Valiulis Erkka Valovirta Tuula Vasankari Maria-Teresa Ventura Samantha Walker Sian Williams Cezmi A Akdis Isabella Annesi-Maesano Sylvie Arnavielhe Xavier Basagana Eric Bateman Anna Bedbrook K S Bennoor Samuel Benveniste Karl C Bergmann Slawomir Bialek Nils Billo Carsten Bindslev-Jensen Leif Bjermer Hubert Blain Mateo Bonini Philippe Bonniaud Jacques Bouchard Vitalis Briedis Christofer E Brightling Jan Brozek Roland Buhl Roland Buonaiuto Giorgo W Canonica Victoria Cardona Ana M Carriazo Warner Carr Christine Cartier Thomas Casale Lorenzo Cecchi Alfonso M Cepeda Sarabia Eka Chkhartishvili Derek K Chu Cemal Cingi Elaine Colgan Jaime Correia de Sousa Anne Lise Courbis Adnan Custovic Biljana Cvetkosvki Gennaro D'Amato Jane da Silva Carina Dantas Dejand Dokic Yves Dauvilliers Antoni Dedeu Giulia De Feo Philippe Devillier Stefania Di Capua Marc Dykewickz Ruta Dubakiene Motohiro Ebisawa Yaya El-Gamal Esben Eller Regina Emuzyte John Farrell Antjie Fink-Wagner Alessandro Fiocchi Jean F Fontaine Bilun Gemicioğlu Peter Schmid-Grendelmeir Amiran Gamkrelidze Judith Garcia-Aymerich Maximiliano Gomez Sandra González Diaz Maia Gotua Nick A Guldemond Maria-Antonieta Guzmán Jawad Hajjam John O'B Hourihane Marc Humbert Guido Iaccarino Despo Ierodiakonou Maddalena Illario Juan C Ivancevich Guy Joos Ki-Suck Jung Marek Jutel Igor Kaidashev Omer Kalayci Przemyslaw Kardas Thomas Keil Mussa Khaitov Nikolai Khaltaev Jorg Kleine-Tebbe Marek L Kowalski Vicky Kritikos Inger Kull Lisa Leonardini Philip Lieberman Brian Lipworth Karin C Lodrup Carlsen Claudia C Loureiro Renaud Louis Alpana Mair Gert Marien Bassam Mahboub Joao Malva Patrick Manning Esteban De Manuel Keenoy Gailen D Marshall Mohamed R Masjedi Jorge F Maspero Eve Mathieu-Dupas Poalo M Matricardi Eric Melén Elisabete Melo-Gomes Eli O Meltzer Enrica Menditto Jacques Mercier Neven Miculinic Florin Mihaltan Branislava Milenkovic Giuliana Moda Maria-Dolores Mogica-Martinez Yousser Mohammad Steve Montefort Ricardo Monti Mario Morais-Almeida Ralf Mösges Lars Münter Antonella Muraro Ruth Murray Robert Naclerio Luigi Napoli Leila Namazova-Baranova Hugo Neffen Kristoff Nekam Angelo Neou Enrico Novellino Dieudonné Nyembue Robin O'Hehir Ken Ohta Kimi Okubo Gabrielle Onorato Solange Ouedraogo Isabella Pali-Schöll Susanna Palkonen Peter Panzner Hae-Sim Park Jean-Louis Pépin Ana-Maria Pereira Oliver Pfaar Ema Paulino Jim Phillips Robert Picard Davor Plavec Ted A Popov Fabienne Portejoie David Price Emmanuel P Prokopakis Benoit Pugin Filip Raciborski Rojin Rajabian-Söderlund Sietze Reitsma Xavier Rodo Antonino Romano Nelson Rosario Menahenm Rottem Dermot Ryan Johanna Salimäki Mario M Sanchez-Borges Juan-Carlos Sisul Dirceu Solé David Somekh Talant Sooronbaev Milan Sova Otto Spranger Cristina Stellato Rafael Stelmach Charlotte Suppli Ulrik Michel Thibaudon Teresa To Ana Todo-Bom Peter V Tomazic Antonio A Valero Rudolph Valenta Marylin Valentin-Rostan Rianne van der Kleij Olivier Vandenplas Giorgio Vezzani Frédéric Viart Giovanni Viegi Dana Wallace Martin Wagenmann De Y Wang Susan Waserman Magnus Wickman Dennis M Williams Gary Wong Piotr Wroczynski Panayiotis K Yiallouros Arzu Yorgancioglu Osman M Yusuf Heahter J Zar Stéphane Zeng Mario Zernotti Luo Zhang Nan S Zhong Mihaela Zidarn

Clin Transl Allergy 2019 9;9:44. Epub 2019 Sep 9.

260University Clinic of Respiratory and Allergic Diseases, Golnik, Slovenia.

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http://dx.doi.org/10.1186/s13601-019-0279-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734297PMC
September 2019

Does maintenance azithromycin reduce asthma exacerbations? An individual participant data meta-analysis.

Eur Respir J 2019 11 28;54(5). Epub 2019 Nov 28.

Centre of Excellence in Severe Asthma and Priority Research Centre for Healthy Lungs, University of Newcastle, Callaghan, Australia.

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http://dx.doi.org/10.1183/13993003.01381-2019DOI Listing
November 2019

The ERS fellowship portfolio: fostering excellence and diversity.

Eur Respir J 2019 09 5;54(3). Epub 2019 Sep 5.

Depts of Epidemiology and Respiratory Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1183/13993003.01503-2019DOI Listing
September 2019

Long-term Safety and Clinical Benefit of Mepolizumab in Patients With the Most Severe Eosinophilic Asthma: The COSMEX Study.

Clin Ther 2019 10 22;41(10):2041-2056.e5. Epub 2019 Aug 22.

Assistance Publique -Hôpitaux de Paris, Service de Pneumologie, Hôpital Bicêtre, Paris, France; Univ. Paris-Sud, Université Paris-Saclay, Paris, France; INSERM U999, Le Kremlin-Bicêtre, Paris, France.

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http://dx.doi.org/10.1016/j.clinthera.2019.07.007DOI Listing
October 2019

Safety of Reslizumab in Uncontrolled Asthma with Eosinophilia: A Pooled Analysis from 6 Trials.

J Allergy Clin Immunol Pract 2020 02 9;8(2):540-548.e1. Epub 2019 Aug 9.

Department of Medicine, Pediatrics, and Radiology, Washington University School of Medicine, St Louis, Mo.

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http://dx.doi.org/10.1016/j.jaip.2019.07.038DOI Listing
February 2020

Prevalence of Asthma and COPD and Blood Eosinophil Count in a Middle-Aged Belgian Population.

J Clin Med 2019 Jul 28;8(8). Epub 2019 Jul 28.

Department of Cardiology and Biobanking and Cardiovascular Epidemiology, Ghent University Hospital and Ghent University, Corneel Heymanslaan 10, 9000 Ghent, Belgium.

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http://dx.doi.org/10.3390/jcm8081122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723474PMC
July 2019

The impact of the prostaglandin D receptor 2 and its downstream effects on the pathophysiology of asthma.

Allergy 2020 04 20;75(4):761-768. Epub 2019 Aug 20.

Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA.

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http://dx.doi.org/10.1111/all.14001DOI Listing
April 2020

Prevalence and burden of asthma in China: time to act.

Lancet 2019 08 20;394(10196):364-366. Epub 2019 Jun 20.

Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.

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http://dx.doi.org/10.1016/S0140-6736(19)31349-2DOI Listing
August 2019

The once-daily fixed-dose combination of olodaterol and tiotropium in the management of COPD: current evidence and future prospects.

Ther Adv Respir Dis 2019 Jan-Dec;13:1753466619843426

Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium.

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http://dx.doi.org/10.1177/1753466619843426DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475840PMC
November 2019

Omalizumab as alternative to chronic use of oral corticosteroids in severe asthma.

Respir Med 2019 04 7;150:51-62. Epub 2019 Feb 7.

Service des Maladies Respiratoires, Hôpital Arnaud de Villeneuve, Montpellier, France. Electronic address:

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http://dx.doi.org/10.1016/j.rmed.2019.02.003DOI Listing
April 2019

Update on immunogenicity in severe asthma: Experience with mepolizumab.

J Allergy Clin Immunol Pract 2019 Sep - Oct;7(7):2469-2475.e1. Epub 2019 Apr 5.

School of Medicine, University of Utah, Utah.

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http://dx.doi.org/10.1016/j.jaip.2019.03.042DOI Listing
April 2019

GDF-15 in Pulmonary and Critical Care Medicine.

Am J Respir Cell Mol Biol 2019 06;60(6):621-628

2 Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, and.

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https://www.atsjournals.org/doi/10.1165/rcmb.2018-0379TR
Publisher Site
http://dx.doi.org/10.1165/rcmb.2018-0379TRDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543753PMC
June 2019

Toward effective prescription of inhaled corticosteroids in chronic airway disease.

Int J Chron Obstruct Pulmon Dis 2018 18;13:3419-3424. Epub 2018 Oct 18.

Respiratory Medicine Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK,

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http://dx.doi.org/10.2147/COPD.S174216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203111PMC
March 2019

Chronic obstructive pulmonary disease and the development of atrial fibrillation.

Int J Cardiol 2019 Feb 15;276:118-124. Epub 2018 Sep 15.

Department of Epidemiology, Erasmus Medical Center, PO Box 2040, Rotterdam 3000, CA, the Netherlands; Department of Bioanalysis, FFW, Ghent University, Ottergemsesteenweg 460, 9000 Ghent, Belgium.

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http://dx.doi.org/10.1016/j.ijcard.2018.09.056DOI Listing
February 2019

ERS Clinical Research Collaborations: underpinning research excellence.

Eur Respir J 2018 09 15;52(3). Epub 2018 Sep 15.

Dept of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium.

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http://dx.doi.org/10.1183/13993003.01534-2018DOI Listing
September 2018

A prospective, longitudinal study evaluating the baseline six-minute walk test as an individual reference value in systemic sclerosis patients.

Clin Exp Rheumatol 2018 Jul-Aug;36 Suppl 113(4):95-101. Epub 2018 Aug 28.

Department of Internal Medicine, Ghent University, and Department of Rheumatology, Ghent University Hospital, Belgium.

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January 2019

Meta-analysis of exome array data identifies six novel genetic loci for lung function.

Authors:
Victoria E Jackson Jeanne C Latourelle Louise V Wain Albert V Smith Megan L Grove Traci M Bartz Ma'en Obeidat Michael A Province Wei Gao Beenish Qaiser David J Porteous Patricia A Cassano Tarunveer S Ahluwalia Niels Grarup Jin Li Elisabeth Altmaier Jonathan Marten Sarah E Harris Ani Manichaikul Tess D Pottinger Ruifang Li-Gao Allan Lind-Thomsen Anubha Mahajan Lies Lahousse Medea Imboden Alexander Teumer Bram Prins Leo-Pekka Lyytikäinen Gudny Eiriksdottir Nora Franceschini Colleen M Sitlani Jennifer A Brody Yohan Bossé Wim Timens Aldi Kraja Anu Loukola Wenbo Tang Yongmei Liu Jette Bork-Jensen Johanne M Justesen Allan Linneberg Leslie A Lange Rajesh Rawal Stefan Karrasch Jennifer E Huffman Blair H Smith Gail Davies Kristin M Burkart Josyf C Mychaleckyj Tobias N Bonten Stefan Enroth Lars Lind Guy G Brusselle Ashish Kumar Beate Stubbe Mika Kähönen Annah B Wyss Bruce M Psaty Susan R Heckbert Ke Hao Taina Rantanen Stephen B Kritchevsky Kurt Lohman Tea Skaaby Charlotta Pisinger Torben Hansen Holger Schulz Ozren Polasek Archie Campbell John M Starr Stephen S Rich Dennis O Mook-Kanamori Åsa Johansson Erik Ingelsson André G Uitterlinden Stefan Weiss Olli T Raitakari Vilmundur Gudnason Kari E North Sina A Gharib Don D Sin Kent D Taylor George T O'Connor Jaakko Kaprio Tamara B Harris Oluf Pederson Henrik Vestergaard James G Wilson Konstantin Strauch Caroline Hayward Shona Kerr Ian J Deary R Graham Barr Renée de Mutsert Ulf Gyllensten Andrew P Morris M Arfan Ikram Nicole Probst-Hensch Sven Gläser Eleftheria Zeggini Terho Lehtimäki David P Strachan Josée Dupuis Alanna C Morrison Ian P Hall Martin D Tobin Stephanie J London

Wellcome Open Res 2018 12;3. Epub 2018 Jan 12.

Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Dept of Health and Human Services, Research Triangle Park, NC, 27709, USA.

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http://dx.doi.org/10.12688/wellcomeopenres.12583.3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081985PMC
January 2018

IL-33 signalling contributes to pollutant-induced allergic airway inflammation.

Clin Exp Allergy 2018 12 19;48(12):1665-1675. Epub 2018 Sep 19.

Department of Respiratory Medicine, Laboratory for Translational Research in Obstructive Pulmonary Diseases, Ghent University Hospital, Ghent, Belgium.

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http://dx.doi.org/10.1111/cea.13261DOI Listing
December 2018

Urgent need for pragmatic trial platforms in severe asthma.

Lancet Respir Med 2018 08;6(8):581-583

Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium; Departments of Epidemiology and Respiratory Medicine, Erasmus Medical Center Rotterdam, Rotterdam, Netherlands. Electronic address:

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http://dx.doi.org/10.1016/S2213-2600(18)30291-1DOI Listing
August 2018

Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function.

Authors:
Annah B Wyss Tamar Sofer Mi Kyeong Lee Natalie Terzikhan Jennifer N Nguyen Lies Lahousse Jeanne C Latourelle Albert Vernon Smith Traci M Bartz Mary F Feitosa Wei Gao Tarunveer S Ahluwalia Wenbo Tang Christopher Oldmeadow Qing Duan Kim de Jong Mary K Wojczynski Xin-Qun Wang Raymond Noordam Fernando Pires Hartwig Victoria E Jackson Tianyuan Wang Ma'en Obeidat Brian D Hobbs Tianxiao Huan Hongsheng Gui Margaret M Parker Donglei Hu Lauren S Mogil Gleb Kichaev Jianping Jin Mariaelisa Graff Tamara B Harris Ravi Kalhan Susan R Heckbert Lavinia Paternoster Kristin M Burkart Yongmei Liu Elizabeth G Holliday James G Wilson Judith M Vonk Jason L Sanders R Graham Barr Renée de Mutsert Ana Maria Baptista Menezes Hieab H H Adams Maarten van den Berge Roby Joehanes Albert M Levin Jennifer Liberto Lenore J Launer Alanna C Morrison Colleen M Sitlani Juan C Celedón Stephen B Kritchevsky Rodney J Scott Kaare Christensen Jerome I Rotter Tobias N Bonten Fernando César Wehrmeister Yohan Bossé Shujie Xiao Sam Oh Nora Franceschini Jennifer A Brody Robert C Kaplan Kurt Lohman Mark McEvoy Michael A Province Frits R Rosendaal Kent D Taylor David C Nickle L Keoki Williams Esteban G Burchard Heather E Wheeler Don D Sin Vilmundur Gudnason Kari E North Myriam Fornage Bruce M Psaty Richard H Myers George O'Connor Torben Hansen Cathy C Laurie Patricia A Cassano Joohon Sung Woo Jin Kim John R Attia Leslie Lange H Marike Boezen Bharat Thyagarajan Stephen S Rich Dennis O Mook-Kanamori Bernardo Lessa Horta André G Uitterlinden Hae Kyung Im Michael H Cho Guy G Brusselle Sina A Gharib Josée Dupuis Ani Manichaikul Stephanie J London

Nat Commun 2018 07 30;9(1):2976. Epub 2018 Jul 30.

Epidemiology Branch National Institute of Environmental Health Sciences, National Institutes of Health, US Department of Health and Human Services, Research Triangle Park, NC, 27709, USA.

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http://dx.doi.org/10.1038/s41467-018-05369-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065313PMC
July 2018

Influence of genetic variants on childhood lung function - The Generation R Study.

Pediatr Allergy Immunol 2018 09 10;29(6):589-595. Epub 2018 Jul 10.

Department of Pediatrics, Division of Respiratory Medicine and Allergology, Division of Neonatology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1111/pai.12931DOI Listing
September 2018

Asthma and its comorbidities in middle-aged and older adults; the Rotterdam Study.

Respir Med 2018 06 11;139:6-12. Epub 2018 Apr 11.

Department of Respiratory Medicine, Ghent University Hospital, Corneel Heymanslaan 10, 9000 Ghent, Belgium; Department of Epidemiology, Erasmus MC - University Medical Center Rotterdam, PO Box 2040, 3000 CA Rotterdam, The Netherlands; Department of Respiratory Medicine Erasmus MC - University Medical Center Rotterdam, PO Box 2040, 3000 CA Rotterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.rmed.2018.04.006DOI Listing
June 2018

Efficacy and Safety of Dupilumab in Glucocorticoid-Dependent Severe Asthma.

N Engl J Med 2018 06 21;378(26):2475-2485. Epub 2018 May 21.

From LungenClinic Grosshansdorf, Grosshansdorf, and Christian Albrechts University Kiel, Kiel - both in Germany (K.F.R.); McMaster University and St. Joseph's Healthcare, Hamilton, ON, Canada (P.N.); Ghent University Hospital, Ghent, Belgium (G.B.); Fundación CIDEA (Centro de Investigación de Enfermedades Alérgicas y Respiratorias), Buenos Aires (J.F.M.); Washington University School of Medicine, St. Louis (M.C.); Peninsula Research Associates, Rolling Hills Estates, CA (L.S.); Sanofi, Bridgewater, NJ (H.Z., B.N.S., H.S., G.P., C.A., A.T.); Regeneron Pharmaceuticals, Tarrytown, NY (J.D.H., J.C., N.A., M.R., B.A., N.M.H.G., N.S., G.D.Y.); and Sanofi, Chilly Mazarin, France (A.K.).

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http://dx.doi.org/10.1056/NEJMoa1804093DOI Listing
June 2018

Serum phosphate levels are related to all-cause, cardiovascular and COPD mortality in men.

Eur J Epidemiol 2018 Sep 15;33(9):859-871. Epub 2018 May 15.

Department of Internal Medicine, Erasmus MC, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1007/s10654-018-0407-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133003PMC
September 2018

Blood eosinophil levels as a biomarker in COPD.

Respir Med 2018 05 15;138:21-31. Epub 2018 Mar 15.

Respiratory Medical Franchise, GSK, Brentford, UK. Electronic address:

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http://dx.doi.org/10.1016/j.rmed.2018.03.016DOI Listing
May 2018

Physical activity and cause-specific mortality: the Rotterdam Study.

Int J Epidemiol 2018 10;47(5):1705-1713

Department of Epidemiology, Erasmus MC - University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1093/ije/dyy058DOI Listing
October 2018

Association of innate defense proteins BPIFA1 and BPIFB1 with disease severity in COPD.

Int J Chron Obstruct Pulmon Dis 2018 19;13:11-27. Epub 2017 Dec 19.

Laboratory for Translational Research in Obstructive Pulmonary Diseases, Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium.

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http://dx.doi.org/10.2147/COPD.S144136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741069PMC
September 2018

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

Authors:
Florence Demenais Patricia Margaritte-Jeannin Kathleen C Barnes William O C Cookson Janine Altmüller Wei Ang R Graham Barr Terri H Beaty Allan B Becker John Beilby Hans Bisgaard Unnur Steina Bjornsdottir Eugene Bleecker Klaus Bønnelykke Dorret I Boomsma Emmanuelle Bouzigon Christopher E Brightling Myriam Brossard Guy G Brusselle Esteban Burchard Kristin M Burkart Andrew Bush Moira Chan-Yeung Kian Fan Chung Alexessander Couto Alves John A Curtin Adnan Custovic Denise Daley Johan C de Jongste Blanca E Del-Rio-Navarro Kathleen M Donohue Liesbeth Duijts Celeste Eng Johan G Eriksson Martin Farrall Yuliya Fedorova Bjarke Feenstra Manuel A Ferreira Maxim B Freidin Zofia Gajdos Jim Gauderman Ulrike Gehring Frank Geller Jon Genuneit Sina A Gharib Frank Gilliland Raquel Granell Penelope E Graves Daniel F Gudbjartsson Tari Haahtela Susan R Heckbert Dick Heederik Joachim Heinrich Markku Heliövaara John Henderson Blanca E Himes Hiroshi Hirose Joel N Hirschhorn Albert Hofman Patrick Holt Jouke Hottenga Thomas J Hudson Jennie Hui Medea Imboden Vladimir Ivanov Vincent W V Jaddoe Alan James Christer Janson Marjo-Riitta Jarvelin Deborah Jarvis Graham Jones Ingileif Jonsdottir Pekka Jousilahti Michael Kabesch Mika Kähönen David B Kantor Alexandra S Karunas Elza Khusnutdinova Gerard H Koppelman Anita L Kozyrskyj Eskil Kreiner Michiaki Kubo Rajesh Kumar Ashish Kumar Mikko Kuokkanen Lies Lahousse Tarja Laitinen Catherine Laprise Mark Lathrop Susanne Lau Young-Ae Lee Terho Lehtimäki Sébastien Letort Albert M Levin Guo Li Liming Liang Laura R Loehr Stephanie J London Daan W Loth Ani Manichaikul Ingo Marenholz Fernando J Martinez Melanie C Matheson Rasika A Mathias Kenji Matsumoto Hamdi Mbarek Wendy L McArdle Mads Melbye Erik Melén Deborah Meyers Sven Michel Hamida Mohamdi Arthur W Musk Rachel A Myers Maartje A E Nieuwenhuis Emiko Noguchi George T O'Connor Ludmila M Ogorodova Cameron D Palmer Aarno Palotie Julie E Park Craig E Pennell Göran Pershagen Alexey Polonikov Dirkje S Postma Nicole Probst-Hensch Valery P Puzyrev Benjamin A Raby Olli T Raitakari Adaikalavan Ramasamy Stephen S Rich Colin F Robertson Isabelle Romieu Muhammad T Salam Veikko Salomaa Vivi Schlünssen Robert Scott Polina A Selivanova Torben Sigsgaard Angela Simpson Valérie Siroux Lewis J Smith Maria Solodilova Marie Standl Kari Stefansson David P Strachan Bruno H Stricker Atsushi Takahashi Philip J Thompson Gudmar Thorleifsson Unnur Thorsteinsdottir Carla M T Tiesler Dara G Torgerson Tatsuhiko Tsunoda André G Uitterlinden Ralf J P van der Valk Amaury Vaysse Sailaja Vedantam Andrea von Berg Erika von Mutius Judith M Vonk Johannes Waage Nick J Wareham Scott T Weiss Wendy B White Magnus Wickman Elisabeth Widén Gonneke Willemsen L Keoki Williams Inge M Wouters James J Yang Jing Hua Zhao Miriam F Moffatt Carole Ober Dan L Nicolae

Nat Genet 2018 01 22;50(1):42-53. Epub 2017 Dec 22.

Departments of Statistics, Human Genetics and Medicine, Section of Genetic Medicine, University of Chicago, Chicago, IL, USA.

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http://www.nature.com/articles/s41588-017-0014-7
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http://dx.doi.org/10.1038/s41588-017-0014-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901974PMC
January 2018

Pulmonary function and diffusion capacity are associated with pulmonary arterial systolic pressure in the general population: The Rotterdam Study.

Respir Med 2017 Nov 21;132:50-55. Epub 2017 Sep 21.

Department of Epidemiology, Erasmus MC - University Medical Center Rotterdam, Rotterdam, The Netherlands; Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium; Department of Respiratory Medicine, Erasmus MC - University Medical Center Rotterdam, Rotterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.rmed.2017.09.009DOI Listing
November 2017

Care pathways for the selection of a biologic in severe asthma.

Eur Respir J 2017 12 7;50(6). Epub 2017 Dec 7.

Dept of Pulmonary and Critical Care Medicine, National Jewish Health, Denver, CO, USA.

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http://dx.doi.org/10.1183/13993003.01782-2017DOI Listing
December 2017

The Significance of Eosinophilic Inflammation in Chronic Obstructive Pulmonary Disease.

Am J Respir Crit Care Med 2018 04;197(7):967-968

5 University of Oxford Oxford, United Kingdom.

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http://www.atsjournals.org/doi/10.1164/rccm.201709-1797LE
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http://dx.doi.org/10.1164/rccm.201709-1797LEDOI Listing
April 2018