Publications by authors named "Guy A Rutter"

246 Publications

Chromatin 3D interaction analysis of the STARD10 locus unveils FCHSD2 as a regulator of insulin secretion.

Cell Rep 2021 Feb;34(5):108703

Section of Cell Biology and Functional Genomics, Department of Medicine, Imperial College London, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK; Lee Kong Chian School of Medicine, Nan Yang Technological University, Singapore, Singapore. Electronic address:

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February 2021

Importance of Both Imprinted Genes and Functional Heterogeneity in Pancreatic Beta Cells: Is There a Link?

Int J Mol Sci 2021 Jan 20;22(3). Epub 2021 Jan 20.

Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology and Metabolism, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, Du Cane Road, London W12 0NN, UK.

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January 2021

Functional Genomics in Pancreatic β Cells: Recent Advances in Gene Deletion and Genome Editing Technologies for Diabetes Research.

Front Endocrinol (Lausanne) 2020 8;11:576632. Epub 2020 Oct 8.

Section of Cell Biology and Functional Genomics, Faculty of Medicine, Imperial College London, London, United Kingdom.

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October 2020

Covid-19 and Diabetes: A Complex Bidirectional Relationship.

Front Endocrinol (Lausanne) 2020 8;11:582936. Epub 2020 Oct 8.

Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology and Metabolism, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom.

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November 2020

Adipocyte-specific deletion of Tcf7l2 induces dysregulated lipid metabolism and impairs glucose tolerance in mice.

Diabetologia 2021 Jan 17;64(1):129-141. Epub 2020 Oct 17.

Section of Cell Biology and Functional Genomics, Department of Metabolism, Digestion and Reproduction, Hammersmith Hospital, Imperial College Centre for Translational and Experimental Medicine, London, UK.

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January 2021

Control by Ca of mitochondrial structure and function in pancreatic β-cells.

Cell Calcium 2020 11 1;91:102282. Epub 2020 Sep 1.

Section of Cell Biology and Functional Genomics, Department of Metabolism, Digestion and Reproduction, Imperial College London, du Cane Road, London, W12 0NN, UK. Electronic address:

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November 2020

Metabolic and functional specialisations of the pancreatic beta cell: gene disallowance, mitochondrial metabolism and intercellular connectivity.

Diabetologia 2020 10 7;63(10):1990-1998. Epub 2020 Sep 7.

Section of Cell Biology and Functional Genomics, Department of Metabolism, Digestion and Reproduction, Imperial College London, Hammersmith Hospital, Du Cane Road, London, W12 0NN, UK.

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October 2020

Loss of β-cell identity and diabetic phenotype in mice caused by disruption of CNOT3-dependent mRNA deadenylation.

Commun Biol 2020 Aug 28;3(1):476. Epub 2020 Aug 28.

Cell Signal Unit, Okinawa Institute of Science and Technology Graduate University, Okinawa, Japan.

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August 2020

Pancreatic islet secretion: gabbling via GABA.

Authors:
Guy A Rutter

Nat Metab 2019 11;1(11):1032-1033

Section of Cell Biology and Functional Genomics, Department of Metabolism, Reproduction and Digestion, Faculty of Medicine, Hammersmith Hospital, Imperial College London, London, UK.

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November 2019

Age matters: Grading granule secretion in beta cells.

J Biol Chem 2020 07;295(27):8912-8913

Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology, and Metabolism, Department of Metabolism, Reproduction, and Digestion, Imperial College London, London, United Kingdom

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July 2020

The pore-forming subunit MCU of the mitochondrial Ca uniporter is required for normal glucose-stimulated insulin secretion in vitro and in vivo in mice.

Diabetologia 2020 07 29;63(7):1368-1381. Epub 2020 Apr 29.

Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology and Metabolism, Department of Metabolism, Digestion and Reproduction, Imperial College London, Du Cane Road, London, W12 0NN, UK.

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July 2020

Synthesis and in vivo behaviour of an exendin-4-based MRI probe capable of β-cell-dependent contrast enhancement in the pancreas.

Dalton Trans 2020 Apr;49(15):4732-4740

Department of Chemistry, Molecular Sciences Research Hub, Imperial College London, White City Campus, Wood Lane, London, W12 0BZ, UK.

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April 2020

Glucocorticoid Metabolism in Obesity and Following Weight Loss.

Front Endocrinol (Lausanne) 2020 20;11:59. Epub 2020 Feb 20.

Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology and Metabolism, Department of Metabolism, Digestion and Reproduction, Imperial Centre for Translational and Experimental Medicine, Imperial College London, London, United Kingdom.

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February 2020

Dietary substitution of SFA with MUFA within high-fat diets attenuates hyperinsulinaemia and pancreatic islet dysfunction.

Br J Nutr 2020 08 3;124(3):247-255. Epub 2020 Mar 3.

Nutrigenomics Research Group, UCD Conway Institute of Biomolecular Research, and School of Public Health, Physiotherapy and Sports Science, University College Dublin, Belfield, Dublin 4, Republic of Ireland.

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August 2020