Gustavo Pacheco-Rodriguez

Gustavo Pacheco-Rodriguez

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Gustavo Pacheco-Rodriguez

Gustavo Pacheco-Rodriguez

Publications by authors named "Gustavo Pacheco-Rodriguez"

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The Lymphangioleiomyomatosis Lung Cell and Its Human Cell Models.

Am J Respir Cell Mol Biol 2018 06;58(6):678-683

1 Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1165/rcmb.2017-0403TRDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002654PMC
June 2018

CA-125 in Disease Progression and Treatment of Lymphangioleiomyomatosis.

Chest 2018 02 30;153(2):339-348. Epub 2017 May 30.

Cardiovascular and Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD. Electronic address:

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http://dx.doi.org/10.1016/j.chest.2017.05.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026218PMC
February 2018

Effect of beta-agonists on LAM progression and treatment.

Proc Natl Acad Sci U S A 2018 01 16;115(5):E944-E953. Epub 2018 Jan 16.

Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892;

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http://dx.doi.org/10.1073/pnas.1719960115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798385PMC
January 2018

and mutations in circulating Langerhans-like CD1a cells in a patient with pulmonary Langerhans' cell histiocytosis.

Eur Respir J 2017 10 12;50(4). Epub 2017 Oct 12.

Cardiovascular and Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA

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http://dx.doi.org/10.1183/13993003.00521-2017DOI Listing
October 2017

Benign Metastasizing Leiomyoma.

Clin Chest Med 2016 09 25;37(3):589-95. Epub 2016 Jun 25.

Cardiovascular and Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Building 10, Room 6D05, MSC-1590, 9000 Rockville Pike, Bethesda, MD 20892-1590, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccm.2016.04.019DOI Listing
September 2016

Electrophoretic characterization of the Mammalian nuclear matrix proteome, nuclear envelope, nucleoli and covalently bound ADP-ribose polymers: potential applications to cancer.

Cancer Genomics Proteomics 2014 Sep-Oct;11(5):217-23

Institute for Cancer Research, University of North Texas System, Fort Worth, TX, U.S.A.

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May 2015

Osteoprotegerin contributes to the metastatic potential of cells with a dysfunctional TSC2 tumor-suppressor gene.

Am J Pathol 2013 Sep 16;183(3):938-50. Epub 2013 Jul 16.

Cardiovascular and Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892-1590, USA.

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http://dx.doi.org/10.1016/j.ajpath.2013.05.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763770PMC
September 2013

Sex-specific lung diseases: effect of oestrogen on cultured cells and in animal models.

Eur Respir Rev 2013 Sep;22(129):302-11

National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1183/09059180.00002813DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4241263PMC
September 2013

Pulmonary lymphangiomatosis.

Lymphat Res Biol 2011 ;9(4):191-3

Cardiovascular and Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892-1590, USA.

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http://dx.doi.org/10.1089/lrb.2011.0023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246407PMC
April 2012

Regulation of growth factor receptor degradation by ADP-ribosylation factor domain protein (ARD) 1.

Proc Natl Acad Sci U S A 2011 Jun 8;108(26):10454-9. Epub 2011 Jun 8.

Cardiovascular and Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1073/pnas.1103867108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3127937PMC
June 2011

Phenotypic characterization of disseminated cells with TSC2 loss of heterozygosity in patients with lymphangioleiomyomatosis.

Am J Respir Crit Care Med 2010 Dec 16;182(11):1410-8. Epub 2010 Jul 16.

Cardiovascular and Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1164/rccm.201003-0489OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3029931PMC
December 2010

The role of chemokines in migration of metastatic-like lymphangioleiomyomatosis cells.

Crit Rev Immunol 2010 ;30(4):387-94

Translational Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892-1590, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3021991PMC
September 2010

Effects of prolactin on TSC2-null Eker rat cells and in pulmonary lymphangioleiomyomatosis.

Am J Respir Crit Care Med 2010 Aug 22;182(4):531-9. Epub 2010 Apr 22.

Translational Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892-1590, USA.

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http://dx.doi.org/10.1164/rccm.200911-1737OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2937243PMC
August 2010

The natural history of lymphangioleiomyomatosis: markers of severity, rate of progression and prognosis.

Lymphat Res Biol 2010 Mar;8(1):9-19

Translational Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892-1590, USA.

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http://dx.doi.org/10.1089/lrb.2009.0024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883494PMC
March 2010

Lymphangioleiomyomatosis and TSC2-/- cells.

Lymphat Res Biol 2010 Mar;8(1):59-69

Department of Dermatology, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, USA.

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http://dx.doi.org/10.1089/lrb.2009.0031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883471PMC
March 2010

Lymphatics in idiopathic pulmonary fibrosis: new insights into an old disease.

Lymphat Res Biol 2009 Dec;7(4):197-203

Translational Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892-1590, USA.

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http://dx.doi.org/10.1089/lrb.2009.0014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883488PMC
December 2009

Involvement of lymphatics in lymphangioleiomyomatosis.

Lymphat Res Biol 2009 Dec;7(4):221-8

Translational Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892-1590, USA.

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http://dx.doi.org/10.1089/lrb.2009.0017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883505PMC
December 2009

Interaction of phosphodiesterase 3A with brefeldin A-inhibited guanine nucleotide-exchange proteins BIG1 and BIG2 and effect on ARF1 activity.

Proc Natl Acad Sci U S A 2009 Apr 30;106(15):6158-63. Epub 2009 Mar 30.

Translational Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1073/pnas.0901558106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2662965PMC
April 2009

Chemokine-enhanced chemotaxis of lymphangioleiomyomatosis cells with mutations in the tumor suppressor TSC2 gene.

J Immunol 2009 Feb;182(3):1270-7

Translational Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947111PMC
http://dx.doi.org/10.4049/jimmunol.182.3.1270DOI Listing
February 2009

Mesenchymal-epithelial interactions involving epiregulin in tuberous sclerosis complex hamartomas.

Proc Natl Acad Sci U S A 2008 Mar 21;105(9):3539-44. Epub 2008 Feb 21.

Department of Dermatology, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814-4712, USA.

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http://dx.doi.org/10.1073/pnas.0712397105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265180PMC
March 2008

Association of guanine nucleotide-exchange protein BIG1 in HepG2 cell nuclei with nucleolin, U3 snoRNA, and fibrillarin.

Proc Natl Acad Sci U S A 2008 Mar 21;105(9):3357-61. Epub 2008 Feb 21.

Translational Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1073/pnas.0712387105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265132PMC
March 2008

Unfolded protein response and cell death after depletion of brefeldin A-inhibited guanine nucleotide-exchange protein GBF1.

Proc Natl Acad Sci U S A 2008 Feb 14;105(8):2877-82. Epub 2008 Feb 14.

Translational Medicine Branch and Proteomics Core Facility, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0712224105
Publisher Site
http://dx.doi.org/10.1073/pnas.0712224105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268553PMC
February 2008

ARL4D recruits cytohesin-2/ARNO to modulate actin remodeling.

Mol Biol Cell 2007 Nov 5;18(11):4420-37. Epub 2007 Sep 5.

Institute of Molecular Medicine, College of Medicine, National Taiwan University, Taipei 100, Taiwan.

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http://dx.doi.org/10.1091/mbc.e07-02-0149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2043562PMC
November 2007

TSC2 loss in lymphangioleiomyomatosis cells correlated with expression of CD44v6, a molecular determinant of metastasis.

Cancer Res 2007 Nov;67(21):10573-81

Pulmonary-Critical Care Medicine Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD 20892-1434, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-07-1356DOI Listing
November 2007

Tissue-specific renin-angiotensin system in pulmonary lymphangioleiomyomatosis.

Am J Respir Cell Mol Biol 2006 Jul 10;35(1):40-7. Epub 2006 Feb 10.

Pulmonary-Critical Care Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1165/rcmb.2005-0387OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2658696PMC
July 2006

Cytohesin-1: structure, function, and ARF activation.

Methods Enzymol 2005 ;404:184-95

Pulmonary-Critical Care Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1016/S0076-6879(05)04018-8DOI Listing
March 2006

Effect of protein kinase A on accumulation of brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1) in HepG2 cell nuclei.

Proc Natl Acad Sci U S A 2006 Feb 8;103(8):2683-8. Epub 2006 Feb 8.

Pulmonary-Critical Care Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://www.pnas.org/content/103/8/2683.full.pdf
Web Search
http://www.pnas.org/cgi/doi/10.1073/pnas.0510571103
Publisher Site
http://dx.doi.org/10.1073/pnas.0510571103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1413798PMC
February 2006

Association of brefeldin A-inhibited guanine nucleotide-exchange protein 2 (BIG2) with recycling endosomes during transferrin uptake.

Proc Natl Acad Sci U S A 2006 Feb 13;103(8):2635-40. Epub 2006 Feb 13.

Pulmonary-Critical Care Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1073/pnas.0510599103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1413799PMC
February 2006

LY303511 (2-piperazinyl-8-phenyl-4H-1-benzopyran-4-one) acts via phosphatidylinositol 3-kinase-independent pathways to inhibit cell proliferation via mammalian target of rapamycin (mTOR)- and non-mTOR-dependent mechanisms.

J Pharmacol Exp Ther 2005 Sep 27;314(3):1134-43. Epub 2005 May 27.

Pulmonary-Critical Care Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1124/jpet.105.083550DOI Listing
September 2005

MCP-1 overexpressed in tuberous sclerosis lesions acts as a paracrine factor for tumor development.

J Exp Med 2005 Sep 29;202(5):617-24. Epub 2005 Aug 29.

Department of Dermatology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.

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http://dx.doi.org/10.1084/jem.20042469DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1378109PMC
September 2005

E3 ubiquitin ligase activity of the trifunctional ARD1 (ADP-ribosylation factor domain protein 1).

Proc Natl Acad Sci U S A 2005 Feb 31;102(6):1945-50. Epub 2005 Jan 31.

Pulmonary-Critical Care Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892-1434, USA.

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http://dx.doi.org/10.1073/pnas.0409800102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC548593PMC
February 2005

Interaction of BIG2, a brefeldin A-inhibited guanine nucleotide-exchange protein, with exocyst protein Exo70.

Proc Natl Acad Sci U S A 2005 Feb 10;102(8):2784-9. Epub 2005 Feb 10.

Pulmonary-Critical Care Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1073/pnas.0409871102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC549493PMC
February 2005

Molecular and genetic analysis of disseminated neoplastic cells in lymphangioleiomyomatosis.

Proc Natl Acad Sci U S A 2004 Dec 6;101(50):17462-7. Epub 2004 Dec 6.

Pulmonary-Critical Care Medicine Branch and Flow Cytometry Core, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1073/pnas.0407971101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC536045PMC
December 2004

Nuclear localization and molecular partners of BIG1, a brefeldin A-inhibited guanine nucleotide-exchange protein for ADP-ribosylation factors.

Proc Natl Acad Sci U S A 2004 Mar 18;101(9):2752-7. Epub 2004 Feb 18.

Pulmonary-Critical Care Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1073/pnas.0307345101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC365693PMC
March 2004

ARF-directed guanine-nucleotide-exchange (GEP) proteins.

Methods Mol Biol 2002 ;189:181-9

Pulmonary-Critical Care Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1385/1-59259-281-3:181DOI Listing
July 2003

Interaction of FK506-binding protein 13 with brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1): effects of FK506.

Proc Natl Acad Sci U S A 2003 Mar 26;100(5):2322-7. Epub 2003 Feb 26.

Pulmonary-Critical Care Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Building 10, Room 5N307, MSC 1434, Bethesda, MD 20892-1434, USA.

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http://dx.doi.org/10.1073/pnas.2628047100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC151339PMC
March 2003

Protein kinase A-anchoring (AKAP) domains in brefeldin A-inhibited guanine nucleotide-exchange protein 2 (BIG2).

Proc Natl Acad Sci U S A 2003 Feb 5;100(4):1627-32. Epub 2003 Feb 5.

Pulmonary-Critical Care Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1073/pnas.0337678100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC149883PMC
February 2003

BIG1 and BIG2: brefeldin A-inhibited guanine nucleotide-exchange proteins for ADP-ribosylation factors.

Methods Enzymol 2002 ;345:397-404

Pulmonary-Critical Care Medicine Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1016/s0076-6879(02)45032-xDOI Listing
April 2002

Giles F. Filley Lecture. Genetics and gene expression in lymphangioleiomyomatosis.

Chest 2002 Mar;121(3 Suppl):56S-60S

Pulmonary-Critical Care Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892-1590, USA.

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http://dx.doi.org/10.1378/chest.121.3_suppl.56sDOI Listing
March 2002