Gustavo Glusman

Gustavo Glusman

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Gustavo Glusman

Gustavo Glusman

Publications by authors named "Gustavo Glusman"

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Sex, Obesity, Diabetes, and Exposure to Particulate Matter among Patients with Severe Asthma: Scientific Insights from a Comparative Analysis of Open Clinical Data Sources during a Five-day Hackathon.

J Biomed Inform 2019 Oct 29:103325. Epub 2019 Oct 29.

North Carolina Translational and Clinical Sciences Institute, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA; Division of Allergy, Immunology and Rheumatology, Center for Environmental Medicine, Asthma & Lung Biology; Department of Pediatrics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

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http://dx.doi.org/10.1016/j.jbi.2019.103325DOI Listing
October 2019

Opportunities and Challenges in Interpreting and Sharing Personal Genomes.

Genes (Basel) 2019 08 25;10(9). Epub 2019 Aug 25.

Institute for Systems Biology, 401 Terry Ave N, Seattle, WA 98109, USA.

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http://dx.doi.org/10.3390/genes10090643DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770764PMC
August 2019

Genotype Fingerprints Enable Fast and Private Comparison of Genetic Testing Results for Research and Direct-to-Consumer Applications.

Genes (Basel) 2018 Oct 4;9(10). Epub 2018 Oct 4.

Institute for Systems Biology, 401 Terry Ave N, Seattle, WA 98109, USA.

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http://dx.doi.org/10.3390/genes9100481DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209914PMC
October 2018

Reply to "Precision medicine in the clouds".

Nat Biotechnol 2018 08;36(8):680-682

Arivale, Seattle, Washington, USA.

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http://dx.doi.org/10.1038/nbt.4211DOI Listing
August 2018

Novel metrics for quantifying bacterial genome composition skews.

BMC Genomics 2018 Jul 11;19(1):528. Epub 2018 Jul 11.

Institute for Systems Biology, 401 Terry Ave N, Seattle, WA, 98109, USA.

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http://dx.doi.org/10.1186/s12864-018-4913-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042203PMC
July 2018

Taking Systems Medicine to Heart.

Circ Res 2018 04;122(9):1276-1289

From the Institute for Systems Biology, Seattle, WA (K.T., R.B., G.G., N.D.P., S.H., L.E.H.).

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http://dx.doi.org/10.1161/CIRCRESAHA.117.310999DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926821PMC
April 2018

Ultrafast Comparison of Personal Genomes via Precomputed Genome Fingerprints.

Front Genet 2017 26;8:136. Epub 2017 Sep 26.

Institute for Systems Biology, Seattle, WA, United States.

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http://dx.doi.org/10.3389/fgene.2017.00136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623000PMC
September 2017

Differences between the genomes of lymphoblastoid cell lines and blood-derived samples.

Adv Genomics Genet 2017 23;7:1-9. Epub 2017 Feb 23.

Institute for Systems Biology, Seattle, WA, USA.

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http://dx.doi.org/10.2147/AGG.S128824DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520659PMC
February 2017

Parent-of-origin-specific signatures of de novo mutations.

Nat Genet 2016 08 20;48(8):935-9. Epub 2016 Jun 20.

Inova Translational Medicine Institute (ITMI), Inova Health Systems, Falls Church, Virginia, USA.

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http://dx.doi.org/10.1038/ng.3597DOI Listing
August 2016

Personalized nutrition through big data.

Nat Biotechnol 2016 Feb;34(2):152-4

Institute for Systems Biology, Seattle, Washington, USA.

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http://dx.doi.org/10.1038/nbt.3476DOI Listing
February 2016

Whole-genome sequencing of the world's oldest people.

PLoS One 2014 12;9(11):e112430. Epub 2014 Nov 12.

Depts. of Developmental Biology and Genetics, Stanford University, Stanford, CA, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0112430PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229186PMC
July 2015

Whole-genome haplotyping approaches and genomic medicine.

Genome Med 2014 25;6(9):73. Epub 2014 Sep 25.

Institute for Systems Biology, Terry Avenue North, Seattle, WA 98109 USA.

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http://dx.doi.org/10.1186/s13073-014-0073-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254418PMC
December 2014

Accurate and robust prediction of genetic relationship from whole-genome sequences.

PLoS One 2014 28;9(2):e85437. Epub 2014 Feb 28.

Institute for Systems Biology, Seattle, Washington, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0085437PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938395PMC
November 2014

Diffuse angiopathy in Adams-Oliver syndrome associated with truncating DOCK6 mutations.

Am J Med Genet A 2014 Oct 4;164A(10):2656-62. Epub 2014 Aug 4.

Department of Medical Genetics and Child and Family Research Institute, University of British Columbia, Vancouver, Canada.

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http://dx.doi.org/10.1002/ajmg.a.36685DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167472PMC
October 2014

Mutations in NOTCH1 cause Adams-Oliver syndrome.

Am J Hum Genet 2014 Sep 14;95(3):275-84. Epub 2014 Aug 14.

Department of Medical Genetics and Child and Family Research Institute, University of British Columbia, Vancouver, BC V6H 3N1, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2014.07.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157158PMC
September 2014

Optimal scaling of digital transcriptomes.

PLoS One 2013 6;8(11):e77885. Epub 2013 Nov 6.

Institute for Systems Biology, Seattle, Washington, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0077885PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819321PMC
August 2014

Realistic artificial DNA sequences as negative controls for computational genomics.

Nucleic Acids Res 2014 Jul 6;42(12):e99. Epub 2014 May 6.

Institute for Systems Biology, 401 Terry Ave. N, Seattle, WA 98109, USA

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http://dx.doi.org/10.1093/nar/gku356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081056PMC
July 2014

An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge.

Authors:
Catherine A Brownstein Alan H Beggs Nils Homer Barry Merriman Timothy W Yu Katherine C Flannery Elizabeth T DeChene Meghan C Towne Sarah K Savage Emily N Price Ingrid A Holm Lovelace J Luquette Elaine Lyon Joseph Majzoub Peter Neupert David McCallie Peter Szolovits Huntington F Willard Nancy J Mendelsohn Renee Temme Richard S Finkel Sabrina W Yum Livija Medne Shamil R Sunyaev Ivan Adzhubey Christopher A Cassa Paul I W de Bakker Hatice Duzkale Piotr Dworzyński William Fairbrother Laurent Francioli Birgit H Funke Monica A Giovanni Robert E Handsaker Kasper Lage Matthew S Lebo Monkol Lek Ignaty Leshchiner Daniel G MacArthur Heather M McLaughlin Michael F Murray Tune H Pers Paz P Polak Soumya Raychaudhuri Heidi L Rehm Rachel Soemedi Nathan O Stitziel Sara Vestecka Jochen Supper Claudia Gugenmus Bernward Klocke Alexander Hahn Max Schubach Mortiz Menzel Saskia Biskup Peter Freisinger Mario Deng Martin Braun Sven Perner Richard J H Smith Janeen L Andorf Jian Huang Kelli Ryckman Val C Sheffield Edwin M Stone Thomas Bair E Ann Black-Ziegelbein Terry A Braun Benjamin Darbro Adam P DeLuca Diana L Kolbe Todd E Scheetz Aiden E Shearer Rama Sompallae Kai Wang Alexander G Bassuk Erik Edens Katherine Mathews Steven A Moore Oleg A Shchelochkov Pamela Trapane Aaron Bossler Colleen A Campbell Jonathan W Heusel Anne Kwitek Tara Maga Karin Panzer Thomas Wassink Douglas Van Daele Hela Azaiez Kevin Booth Nic Meyer Michael M Segal Marc S Williams Gerard Tromp Peter White Donald Corsmeier Sara Fitzgerald-Butt Gail Herman Devon Lamb-Thrush Kim L McBride David Newsom Christopher R Pierson Alexander T Rakowsky Aleš Maver Luca Lovrečić Anja Palandačić Borut Peterlin Ali Torkamani Anna Wedell Mikael Huss Andrey Alexeyenko Jessica M Lindvall Måns Magnusson Daniel Nilsson Henrik Stranneheim Fulya Taylan Christian Gilissen Alexander Hoischen Bregje van Bon Helger Yntema Marcel Nelen Weidong Zhang Jason Sager Lu Zhang Kathryn Blair Deniz Kural Michael Cariaso Greg G Lennon Asif Javed Saloni Agrawal Pauline C Ng Komal S Sandhu Shuba Krishna Vamsi Veeramachaneni Ofer Isakov Eran Halperin Eitan Friedman Noam Shomron Gustavo Glusman Jared C Roach Juan Caballero Hannah C Cox Denise Mauldin Seth A Ament Lee Rowen Daniel R Richards F Anthony San Lucas Manuel L Gonzalez-Garay C Thomas Caskey Yu Bai Ying Huang Fang Fang Yan Zhang Zhengyuan Wang Jorge Barrera Juan M Garcia-Lobo Domingo González-Lamuño Javier Llorca Maria C Rodriguez Ignacio Varela Martin G Reese Francisco M De La Vega Edward Kiruluta Michele Cargill Reece K Hart Jon M Sorenson Gholson J Lyon David A Stevenson Bruce E Bray Barry M Moore Karen Eilbeck Mark Yandell Hongyu Zhao Lin Hou Xiaowei Chen Xiting Yan Mengjie Chen Cong Li Can Yang Murat Gunel Peining Li Yong Kong Austin C Alexander Zayed I Albertyn Kym M Boycott Dennis E Bulman Paul M K Gordon A Micheil Innes Bartha M Knoppers Jacek Majewski Christian R Marshall Jillian S Parboosingh Sarah L Sawyer Mark E Samuels Jeremy Schwartzentruber Isaac S Kohane David M Margulies

Genome Biol 2014 Mar 25;15(3):R53. Epub 2014 Mar 25.

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http://dx.doi.org/10.1186/gb-2014-15-3-r53DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4073084PMC
March 2014

Relationship estimation from whole-genome sequence data.

PLoS Genet 2014 Jan 30;10(1):e1004144. Epub 2014 Jan 30.

Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1004144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907355PMC
January 2014

Clinical applications of sequencing take center stage.

Authors:
Gustavo Glusman

Genome Biol 2013 Mar 28;14(3):303. Epub 2013 Mar 28.

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http://dx.doi.org/10.1186/gb-2013-14-3-303DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663085PMC
March 2013

P4 medicine: how systems medicine will transform the healthcare sector and society.

Per Med 2013 ;10(6):565-576

Institute for Systems Biology, 401 Terry Avenue North, Seattle, WA 98109, USA.

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http://dx.doi.org/10.2217/pme.13.57DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204402PMC
January 2013

Kaviar: an accessible system for testing SNV novelty.

Bioinformatics 2011 Nov 28;27(22):3216-7. Epub 2011 Sep 28.

Institute for Systems Biology, Seattle, WA 98109, USA.

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http://dx.doi.org/10.1093/bioinformatics/btr540DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208392PMC
November 2011

Parasitoid wasp affects metabolism of cockroach host to favor food preservation for its offspring.

J Comp Physiol A Neuroethol Sens Neural Behav Physiol 2005 Jun 29;191(6):529-34. Epub 2005 Apr 29.

Department of Life Sciences and Zlotowski Center for Neuroscience, Ben-Gurion University of the Negev, P.O. Box 653, Beer-Sheva, 84105, Israel.

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http://dx.doi.org/10.1007/s00359-005-0620-1DOI Listing
June 2005

A comparison of the human and chimpanzee olfactory receptor gene repertoires.

Genome Res 2005 Feb;15(2):224-30

Yale University School of Medicine, Department of Genetics, New Haven, Connecticut 06520, USA.

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http://dx.doi.org/10.1101/gr.2846405DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC546523PMC
February 2005

T1DBase, a community web-based resource for type 1 diabetes research.

Nucleic Acids Res 2005 Jan;33(Database issue):D544-9

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust/MRC Building, Cambridge CB2 2XY, UK.

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http://dx.doi.org/10.1093/nar/gki095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC540049PMC
January 2005

An enigmatic fourth runt domain gene in the fugu genome: ancestral gene loss versus accelerated evolution.

BMC Evol Biol 2004 Nov 4;4:43. Epub 2004 Nov 4.

Institute for Systems Biology, 1441 N 34th St,, Seattle, WA 98103, USA.

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http://dx.doi.org/10.1186/1471-2148-4-43DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC533870PMC
November 2004

Genetic divergence of the rhesus macaque major histocompatibility complex.

Genome Res 2004 Aug;14(8):1501-15

The Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.

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http://dx.doi.org/10.1101/gr.2134504DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC509259PMC
August 2004

Low-pass sequencing for microbial comparative genomics.

BMC Genomics 2004 Jan 12;5(1). Epub 2004 Jan 12.

Institute for Systems Biology, Seattle, Washington 98103, USA.

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http://dx.doi.org/10.1186/1471-2164-5-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC331400PMC
January 2004

Initial sequencing and comparative analysis of the mouse genome.

Authors:
Robert H Waterston Kerstin Lindblad-Toh Ewan Birney Jane Rogers Josep F Abril Pankaj Agarwal Richa Agarwala Rachel Ainscough Marina Alexandersson Peter An Stylianos E Antonarakis John Attwood Robert Baertsch Jonathon Bailey Karen Barlow Stephan Beck Eric Berry Bruce Birren Toby Bloom Peer Bork Marc Botcherby Nicolas Bray Michael R Brent Daniel G Brown Stephen D Brown Carol Bult John Burton Jonathan Butler Robert D Campbell Piero Carninci Simon Cawley Francesca Chiaromonte Asif T Chinwalla Deanna M Church Michele Clamp Christopher Clee Francis S Collins Lisa L Cook Richard R Copley Alan Coulson Olivier Couronne James Cuff Val Curwen Tim Cutts Mark Daly Robert David Joy Davies Kimberly D Delehaunty Justin Deri Emmanouil T Dermitzakis Colin Dewey Nicholas J Dickens Mark Diekhans Sheila Dodge Inna Dubchak Diane M Dunn Sean R Eddy Laura Elnitski Richard D Emes Pallavi Eswara Eduardo Eyras Adam Felsenfeld Ginger A Fewell Paul Flicek Karen Foley Wayne N Frankel Lucinda A Fulton Robert S Fulton Terrence S Furey Diane Gage Richard A Gibbs Gustavo Glusman Sante Gnerre Nick Goldman Leo Goodstadt Darren Grafham Tina A Graves Eric D Green Simon Gregory Roderic Guigó Mark Guyer Ross C Hardison David Haussler Yoshihide Hayashizaki LaDeana W Hillier Angela Hinrichs Wratko Hlavina Timothy Holzer Fan Hsu Axin Hua Tim Hubbard Adrienne Hunt Ian Jackson David B Jaffe L Steven Johnson Matthew Jones Thomas A Jones Ann Joy Michael Kamal Elinor K Karlsson Donna Karolchik Arkadiusz Kasprzyk Jun Kawai Evan Keibler Cristyn Kells W James Kent Andrew Kirby Diana L Kolbe Ian Korf Raju S Kucherlapati Edward J Kulbokas David Kulp Tom Landers J P Leger Steven Leonard Ivica Letunic Rosie Levine Jia Li Ming Li Christine Lloyd Susan Lucas Bin Ma Donna R Maglott Elaine R Mardis Lucy Matthews Evan Mauceli John H Mayer Megan McCarthy W Richard McCombie Stuart McLaren Kirsten McLay John D McPherson Jim Meldrim Beverley Meredith Jill P Mesirov Webb Miller Tracie L Miner Emmanuel Mongin Kate T Montgomery Michael Morgan Richard Mott James C Mullikin Donna M Muzny William E Nash Joanne O Nelson Michael N Nhan Robert Nicol Zemin Ning Chad Nusbaum Michael J O'Connor Yasushi Okazaki Karen Oliver Emma Overton-Larty Lior Pachter Genís Parra Kymberlie H Pepin Jane Peterson Pavel Pevzner Robert Plumb Craig S Pohl Alex Poliakov Tracy C Ponce Chris P Ponting Simon Potter Michael Quail Alexandre Reymond Bruce A Roe Krishna M Roskin Edward M Rubin Alistair G Rust Ralph Santos Victor Sapojnikov Brian Schultz Jörg Schultz Matthias S Schwartz Scott Schwartz Carol Scott Steven Seaman Steve Searle Ted Sharpe Andrew Sheridan Ratna Shownkeen Sarah Sims Jonathan B Singer Guy Slater Arian Smit Douglas R Smith Brian Spencer Arne Stabenau Nicole Stange-Thomann Charles Sugnet Mikita Suyama Glenn Tesler Johanna Thompson David Torrents Evanne Trevaskis John Tromp Catherine Ucla Abel Ureta-Vidal Jade P Vinson Andrew C Von Niederhausern Claire M Wade Melanie Wall Ryan J Weber Robert B Weiss Michael C Wendl Anthony P West Kris Wetterstrand Raymond Wheeler Simon Whelan Jamey Wierzbowski David Willey Sophie Williams Richard K Wilson Eitan Winter Kim C Worley Dudley Wyman Shan Yang Shiaw-Pyng Yang Evgeny M Zdobnov Michael C Zody Eric S Lander

Nature 2002 Dec;420(6915):520-62

Genome Sequencing Center, Washington University School of Medicine, Campus Box 8501, 4444 Forest Park Avenue, St Louis, Missouri 63108, USA.

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http://dx.doi.org/10.1038/nature01262DOI Listing
December 2002