Publications by authors named "Gustavo Baldassarre"

82Publications

HSP90 identified by a proteomic approach as druggable target to reverse platinum-resistance in ovarian cancer.

Mol Oncol 2020 Dec 16. Epub 2020 Dec 16.

Experimental Pharmacology Unit-Laboratories of Naples and Mercogliano (AV), Istituto Nazionale per lo Studio e la Cura dei Tumori "Fondazione G. Pascale" - IRCCS, 80131, Naples, Italy.

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December 2020

RNA splicing alteration in the response to platinum chemotherapy in ovarian cancer: A possible biomarker and therapeutic target.

Med Res Rev 2021 Jan 14;41(1):586-615. Epub 2020 Oct 14.

Molecular Oncology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, National Cancer Institute, Aviano, Italy.

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January 2021

A new role for IDH1 in the control of ovarian cancer cells metabolism and senescence.

Ann Transl Med 2020 Jun;8(12):780

Division of Molecular Oncology, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, National Cancer Institute, Aviano, Italy.

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June 2020

Differential miRNAs expression pattern of irradiated breast cancer cell lines is correlated with radiation sensitivity.

Sci Rep 2020 06 3;10(1):9054. Epub 2020 Jun 3.

Division of Experimental Oncology 2, Department of Translational Research, CRO, National Cancer Institute, Aviano, Italy.

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June 2020

Splicing factor proline- and glutamine-rich (SFPQ) protein regulates platinum response in ovarian cancer-modulating SRSF2 activity.

Oncogene 2020 05 24;39(22):4390-4403. Epub 2020 Apr 24.

Division of Molecular Oncology, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, National Cancer Institute, 33081, Aviano, PN, Italy.

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May 2020

Identification and Characterization of a New Platinum-Induced TP53 Mutation in MDAH Ovarian Cancer Cells.

Cells 2019 12 21;9(1). Epub 2019 Dec 21.

Division of Molecular Oncology, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, National Cancer Institute, Via Franco Gallini 2, 33081 Aviano, Italy.

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December 2019

Multiplex staining depicts the immune infiltrate in colitis-induced colon cancer model.

Sci Rep 2019 09 2;9(1):12645. Epub 2019 Sep 2.

Molecular Oncology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy.

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September 2019

Pathologist second opinion significantly alters clinical management of pT1 endoscopically resected colorectal cancer.

Virchows Arch 2019 Nov 17;475(5):665-668. Epub 2019 Jun 17.

Faculty of Medicine and Psychology, Department of Clinical and Molecular Medicine, University of Rome "Sapienza", Santo Andrea Hospital, via di Grottarossa 1035, 00189, Rome, Italy.

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November 2019

p27kip1 at the crossroad between actin and microtubule dynamics.

Cell Div 2019 1;14. Epub 2019 Apr 1.

1Division of Molecular Oncology, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, National Cancer Institute, 33081 Aviano, Italy.

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April 2019

STAT3 in Breast Cancer Onset and Progression: A Matter of Time and Context.

Int J Mol Sci 2018 Sep 18;19(9). Epub 2018 Sep 18.

Unit of Molecular Oncology, Department of Advanced Cancer Research and Diagnostics, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, National Cancer Institute, 33081 Aviano, Italy.

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September 2018

Exploring the Role of Fallopian Ciliated Cells in the Pathogenesis of High-Grade Serous Ovarian Cancer.

Int J Mol Sci 2018 Aug 24;19(9). Epub 2018 Aug 24.

Division of Molecular Oncology, Department of Translational Research, IRCCS CRO Aviano-National Cancer Institute, Via Franco Gallini, 2 33081 Aviano PN, Italy.

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August 2018

Landscape of CDKN1B Mutations in Luminal Breast Cancer and Other Hormone-Driven Human Tumors.

Front Endocrinol (Lausanne) 2018 17;9:393. Epub 2018 Jul 17.

Division of Molecular Oncology, CRO of Aviano, IRCCS, National Cancer Institute, Aviano, Italy.

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July 2018

p27kip1: An all-round tumor suppressor.

Mol Cell Oncol 2016 18;3(5):e1141742. Epub 2016 Feb 18.

Division of Experimental Oncology 2, Department of Translational Research, CRO Aviano, National Cancer Institute , Aviano, Italy.

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February 2016

Preclinical validation of a novel compound targeting p70S6 kinase in breast cancer.

Aging (Albany NY) 2016 05;8(5):958-76

Division of Molecular Oncology, CRO, National Cancer Institute, Aviano 33081, Italy.

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May 2016

Molecular biology of breast tumors and prognosis.

F1000Res 2016 21;5. Epub 2016 Apr 21.

Department of Experimental Oncology, Department of Translational Research, CRO Aviano IRCCS, National Cancer Institute, Italy, Aviano, Italy.

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May 2016

Meet me in the cytoplasm: A role for p27(Kip1) in the control of H-Ras.

Small GTPases 2016 04 8;7(2):71-5. Epub 2016 Apr 8.

a Division of Experimental Oncology 2, Department of Translational Research, C.R.O. Aviano IRCCS, National Cancer Institute , Aviano , Italy.

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April 2016

p27kip1 controls H-Ras/MAPK activation and cell cycle entry via modulation of MT stability.

Proc Natl Acad Sci U S A 2015 Nov 28;112(45):13916-21. Epub 2015 Oct 28.

Division of Experimental Oncology 2, Department of Translational Research, Centro di Riferimento Oncologico (CRO Aviano), National Cancer Institute, 33081 Aviano, Italy;

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November 2015

SUMOylation regulates p27Kip1 stability and localization in response to TGFβ.

J Mol Cell Biol 2016 Feb 8;8(1):17-30. Epub 2015 Oct 8.

Division of Experimental Oncology 2 Centro di Riferimento Oncologico, National Cancer Institute, Aviano 33081, Italy

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February 2016

Time-tuning cancer therapy.

Aging (Albany NY) 2015 Aug;7(8):531-2

Division of Experimental Oncology 2, Department of Translational Research, C.R.O. Aviano IRCCS, National Cancer Institute, 33081 Aviano, Italy.

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August 2015

Roles of CDKN1B in cancer?

Aging (Albany NY) 2015 Aug;7(8):529-30

Division of Experimental Oncology 2, Department of Translational Research, C.R.O. Aviano IRCCS, National Cancer Institute, 33081 Aviano, Italy.

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August 2015

Prognostic role of bowel involvement in optimally cytoreduced advanced ovarian cancer: a retrospective study.

J Ovarian Res 2014 Jul 9;7:72. Epub 2014 Jul 9.

Department of Gynecological Oncology of Centro di Riferimento Oncologico (CRO) National Cancer Institute, via Gallini 2, I-33019 Aviano, (PN), Italy.

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July 2014

LZTS1 downregulation confers paclitaxel resistance and is associated with worse prognosis in breast cancer.

Oncotarget 2014 Feb;5(4):970-7

Department of Molecular Virology, Immunology and Medical Genetics, Ohio State University Wexner Medical Center and Comprehensive Cancer Center, Columbus, Ohio, USA.

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February 2014

Stathmin is dispensable for tumor onset in mice.

PLoS One 2012 20;7(9):e45561. Epub 2012 Sep 20.

Division of Experimental Oncology 2, CRO, National Cancer Institute, Aviano, Italy.

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March 2013

New light on p27(kip1) in breast cancer.

Cell Cycle 2012 Oct 16;11(19):3701-2. Epub 2012 Aug 16.

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October 2012

Stathmin: a protein with many tasks. New biomarker and potential target in cancer.

Expert Opin Ther Targets 2011 Nov 7;15(11):1249-66. Epub 2011 Oct 7.

National Cancer Institute, Centro di Riferimento Oncologico, Division of Experimental Oncology 2, Via Franco Gallini, 2, 33081 Aviano, Italy.

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November 2011

Role of T198 modification in the regulation of p27(Kip1) protein stability and function.

PLoS One 2011 Mar 14;6(3):e17673. Epub 2011 Mar 14.

Division of Experimental Oncology 2, Centro di Riferimento Oncologico, National Cancer Institute, Aviano, Italy.

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March 2011

Alteration of G1/S transition regulators influences recurrences in head and neck squamous carcinomas.

J Cell Physiol 2012 Jan;227(1):233-8

Division of Pathology, Centro di Riferimento Oncologico, Istituto Nazionale Tumori, IRCCS, Aviano, Italy.

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January 2012

Role of glucocorticoids in breast cancer.

Curr Pharm Des 2010 ;16(32):3593-600

Research Department of Surgery, University College London, UK.

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May 2011

p27Kip1 expression inhibits glioblastoma growth, invasion, and tumor-induced neoangiogenesis.

Mol Cancer Ther 2008 May;7(5):1164-75

Division of Experimental Oncology 2, Centro di Riferimento Oncologico, Istituto Nazionale Tumori, IRCCS, Via Franco Gallini, 2 33081 Aviano, Italy.

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May 2008

Stathmin activity influences sarcoma cell shape, motility, and metastatic potential.

Mol Biol Cell 2008 May 27;19(5):2003-13. Epub 2008 Feb 27.

Division of Experimental Oncology 2, Division of Pathology, and Clinical and Experimental Hematology Research Unit, Centro di Riferimento Oncologico, Istituto Nazionale Tumori, IRCCS Aviano 33081, Italy.

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May 2008

Take your "M" time.

Cell Cycle 2007 Sep 21;6(17):2087-90. Epub 2007 Jun 21.

Division of Experimental Oncology 2, Centro di Riferimento Oncologico, Aviano, Italy.

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September 2007

Fez1/Lzts1 a new mitotic regulator implicated in cancer development.

Cell Div 2007 Aug 24;2:24. Epub 2007 Aug 24.

Department of Molecular Virology, Immunology and Medical Genetics and Comprehensive Cancer Center, Ohio State University, OH, USA.

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August 2007

Haploinsufficiency of the Hmga1 gene causes cardiac hypertrophy and myelo-lymphoproliferative disorders in mice.

Cancer Res 2006 Mar;66(5):2536-43

Istituto di Endocrinologia ed Oncologia Sperimentale del Consiglio Nazionale delle Ricerche c/o Dipartimento di Biologia e Patologia Cellulare e Molecolare, Università di Napoli Federico II, Italy.

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March 2006

Reduced E-cadherin expression contributes to the loss of p27kip1-mediated mechanism of contact inhibition in thyroid anaplastic carcinomas.

Carcinogenesis 2005 Jun 17;26(6):1021-34. Epub 2005 Feb 17.

Dipartimento di Biologia e Patologia Cellulare e Molecolare L.Califano Facoltà di Medicina e Chirurgia, Università Federico II, via S. Pansini 5, 80131, Napoli, Italy.

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June 2005

p27(Kip1)-stathmin interaction influences sarcoma cell migration and invasion.

Cancer Cell 2005 Jan;7(1):51-63

Oncologia Sperimentale 2, Centro di Riferimento Oncologico, Istituto Nazionale Tumori, IRCCS, Aviano 33081, Italy.

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January 2005

Linking inflammation to cell cycle progression.

Curr Pharm Des 2004 ;10(14):1653-66

Divisione di Oncologia Sperimentale 2, Centro di Riferimento Oncologico, Istituto Nazionale Tumori, IRCCS Aviano 33081, Italy.

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June 2004

Loss of Hmga1 gene function affects embryonic stem cell lympho-hematopoietic differentiation.

FASEB J 2003 Aug 17;17(11):1496-8. Epub 2003 Jun 17.

Dipartimento di Biologia e Patologia Cellulare e Molecolare c/o Centro di Endocrinologia ed Oncologia Sperimentale del CNR, Facoltà di Medicina e Chirurgia, Università degli Studi di Napoli Federico II, via Pansini 5, 80131 Naples, Italy.

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August 2003

Overexpression of the HMGA2 gene in transgenic mice leads to the onset of pituitary adenomas.

Oncogene 2002 May;21(20):3190-8

Dipartimento di Biologia e Patologia Cellulare e Molecolare, Centro di Endocrinologia ed Oncologia Sperimentale del CNR, Facoltà di Medicina e Chirurgia di Napoli, Federico II Università degli Studi di Napoli, via Pansini 5, 80131 Naples, Italy.

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May 2002