Gustavo Baldassarre

Gustavo Baldassarre

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Gustavo Baldassarre

Gustavo Baldassarre

Publications by authors named "Gustavo Baldassarre"

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Multiplex staining depicts the immune infiltrate in colitis-induced colon cancer model.

Sci Rep 2019 Sep 2;9(1):12645. Epub 2019 Sep 2.

Molecular Oncology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy.

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http://dx.doi.org/10.1038/s41598-019-49164-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718623PMC
September 2019

Pathologist second opinion significantly alters clinical management of pT1 endoscopically resected colorectal cancer.

Virchows Arch 2019 Jun 17. Epub 2019 Jun 17.

Faculty of Medicine and Psychology, Department of Clinical and Molecular Medicine, University of Rome "Sapienza", Santo Andrea Hospital, via di Grottarossa 1035, 00189, Rome, Italy.

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http://link.springer.com/10.1007/s00428-019-02603-y
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http://dx.doi.org/10.1007/s00428-019-02603-yDOI Listing
June 2019

p27kip1 at the crossroad between actin and microtubule dynamics.

Cell Div 2019 1;14. Epub 2019 Apr 1.

1Division of Molecular Oncology, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, National Cancer Institute, 33081 Aviano, Italy.

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https://celldiv.biomedcentral.com/articles/10.1186/s13008-01
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http://dx.doi.org/10.1186/s13008-019-0045-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442415PMC
April 2019

STAT3 in Breast Cancer Onset and Progression: A Matter of Time and Context.

Int J Mol Sci 2018 Sep 18;19(9). Epub 2018 Sep 18.

Unit of Molecular Oncology, Department of Advanced Cancer Research and Diagnostics, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, National Cancer Institute, 33081 Aviano, Italy.

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http://dx.doi.org/10.3390/ijms19092818DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163512PMC
September 2018

Exploring the Role of Fallopian Ciliated Cells in the Pathogenesis of High-Grade Serous Ovarian Cancer.

Int J Mol Sci 2018 Aug 24;19(9). Epub 2018 Aug 24.

Division of Molecular Oncology, Department of Translational Research, IRCCS CRO Aviano-National Cancer Institute, Via Franco Gallini, 2 33081 Aviano PN, Italy.

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http://www.mdpi.com/1422-0067/19/9/2512
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http://dx.doi.org/10.3390/ijms19092512DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163198PMC
August 2018

Landscape of CDKN1B Mutations in Luminal Breast Cancer and Other Hormone-Driven Human Tumors.

Front Endocrinol (Lausanne) 2018 17;9:393. Epub 2018 Jul 17.

Division of Molecular Oncology, CRO of Aviano, IRCCS, National Cancer Institute, Aviano, Italy.

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https://www.frontiersin.org/article/10.3389/fendo.2018.00393
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http://dx.doi.org/10.3389/fendo.2018.00393DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056726PMC
July 2018

Molecular biology of breast tumors and prognosis.

F1000Res 2016 21;5. Epub 2016 Apr 21.

Department of Experimental Oncology, Department of Translational Research, CRO Aviano IRCCS, National Cancer Institute, Italy, Aviano, Italy.

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http://dx.doi.org/10.12688/f1000research.8158.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841196PMC
May 2016

Preclinical validation of a novel compound targeting p70S6 kinase in breast cancer.

Aging (Albany NY) 2016 05;8(5):958-76

Division of Molecular Oncology, CRO, National Cancer Institute, Aviano 33081, Italy.

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http://dx.doi.org/10.18632/aging.100954DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931847PMC
May 2016

Meet me in the cytoplasm: A role for p27(Kip1) in the control of H-Ras.

Small GTPases 2016 04 8;7(2):71-5. Epub 2016 Apr 8.

a Division of Experimental Oncology 2, Department of Translational Research, C.R.O. Aviano IRCCS, National Cancer Institute , Aviano , Italy.

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http://dx.doi.org/10.1080/21541248.2016.1171279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905269PMC
April 2016

SUMOylation regulates p27Kip1 stability and localization in response to TGFβ.

J Mol Cell Biol 2016 Feb 8;8(1):17-30. Epub 2015 Oct 8.

Division of Experimental Oncology 2 Centro di Riferimento Oncologico, National Cancer Institute, Aviano 33081, Italy

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http://dx.doi.org/10.1093/jmcb/mjv056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943672PMC
February 2016

p27kip1: An all-round tumor suppressor.

Mol Cell Oncol 2016 18;3(5):e1141742. Epub 2016 Feb 18.

Division of Experimental Oncology 2, Department of Translational Research, CRO Aviano, National Cancer Institute , Aviano, Italy.

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http://dx.doi.org/10.1080/23723556.2016.1141742DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295474PMC
February 2016

p27kip1 controls H-Ras/MAPK activation and cell cycle entry via modulation of MT stability.

Proc Natl Acad Sci U S A 2015 Nov 28;112(45):13916-21. Epub 2015 Oct 28.

Division of Experimental Oncology 2, Department of Translational Research, Centro di Riferimento Oncologico (CRO Aviano), National Cancer Institute, 33081 Aviano, Italy;

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http://dx.doi.org/10.1073/pnas.1508514112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653222PMC
November 2015

Roles of CDKN1B in cancer?

Aging (Albany NY) 2015 Aug;7(8):529-30

Division of Experimental Oncology 2, Department of Translational Research, C.R.O. Aviano IRCCS, National Cancer Institute, 33081 Aviano, Italy.

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http://www.aging-us.com/article/100786
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586097PMC
http://dx.doi.org/10.18632/aging.100786DOI Listing
August 2015

Time-tuning cancer therapy.

Aging (Albany NY) 2015 Aug;7(8):531-2

Division of Experimental Oncology 2, Department of Translational Research, C.R.O. Aviano IRCCS, National Cancer Institute, 33081 Aviano, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586098PMC
http://dx.doi.org/10.18632/aging.100793DOI Listing
August 2015

Prognostic role of bowel involvement in optimally cytoreduced advanced ovarian cancer: a retrospective study.

J Ovarian Res 2014 Jul 9;7:72. Epub 2014 Jul 9.

Department of Gynecological Oncology of Centro di Riferimento Oncologico (CRO) National Cancer Institute, via Gallini 2, I-33019 Aviano, (PN), Italy.

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http://dx.doi.org/10.1186/1757-2215-7-72DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100746PMC
July 2014

LZTS1 downregulation confers paclitaxel resistance and is associated with worse prognosis in breast cancer.

Oncotarget 2014 Feb;5(4):970-7

Department of Molecular Virology, Immunology and Medical Genetics, Ohio State University Wexner Medical Center and Comprehensive Cancer Center, Columbus, Ohio, USA.

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http://www.oncotarget.com/fulltext/1630
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011598PMC
http://dx.doi.org/10.18632/oncotarget.1630DOI Listing
February 2014

New light on p27(kip1) in breast cancer.

Cell Cycle 2012 Oct 16;11(19):3701-2. Epub 2012 Aug 16.

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http://dx.doi.org/10.4161/cc.21573DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478320PMC
October 2012

Alteration of G1/S transition regulators influences recurrences in head and neck squamous carcinomas.

J Cell Physiol 2012 Jan;227(1):233-8

Division of Pathology, Centro di Riferimento Oncologico, Istituto Nazionale Tumori, IRCCS, Aviano, Italy.

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http://dx.doi.org/10.1002/jcp.22723DOI Listing
January 2012

Stathmin: a protein with many tasks. New biomarker and potential target in cancer.

Expert Opin Ther Targets 2011 Nov 7;15(11):1249-66. Epub 2011 Oct 7.

National Cancer Institute, Centro di Riferimento Oncologico, Division of Experimental Oncology 2, Via Franco Gallini, 2, 33081 Aviano, Italy.

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http://dx.doi.org/10.1517/14728222.2011.620951DOI Listing
November 2011

Role of glucocorticoids in breast cancer.

Curr Pharm Des 2010 ;16(32):3593-600

Research Department of Surgery, University College London, UK.

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http://dx.doi.org/10.2174/138161210793797906DOI Listing
May 2011

Role of T198 modification in the regulation of p27(Kip1) protein stability and function.

PLoS One 2011 Mar 14;6(3):e17673. Epub 2011 Mar 14.

Division of Experimental Oncology 2, Centro di Riferimento Oncologico, National Cancer Institute, Aviano, Italy.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0017673PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3056717PMC
March 2011

Stathmin activity influences sarcoma cell shape, motility, and metastatic potential.

Mol Biol Cell 2008 May 27;19(5):2003-13. Epub 2008 Feb 27.

Division of Experimental Oncology 2, Division of Pathology, and Clinical and Experimental Hematology Research Unit, Centro di Riferimento Oncologico, Istituto Nazionale Tumori, IRCCS Aviano 33081, Italy.

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http://dx.doi.org/10.1091/mbc.e07-09-0894DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2366875PMC
May 2008

p27Kip1 expression inhibits glioblastoma growth, invasion, and tumor-induced neoangiogenesis.

Mol Cancer Ther 2008 May;7(5):1164-75

Division of Experimental Oncology 2, Centro di Riferimento Oncologico, Istituto Nazionale Tumori, IRCCS, Via Franco Gallini, 2 33081 Aviano, Italy.

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http://dx.doi.org/10.1158/1535-7163.MCT-07-2154DOI Listing
May 2008

Take your "M" time.

Cell Cycle 2007 Sep 21;6(17):2087-90. Epub 2007 Jun 21.

Division of Experimental Oncology 2, Centro di Riferimento Oncologico, Aviano, Italy.

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http://www.tandfonline.com/doi/abs/10.4161/cc.6.17.4628
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http://dx.doi.org/10.4161/cc.6.17.4628DOI Listing
September 2007

Fez1/Lzts1 a new mitotic regulator implicated in cancer development.

Cell Div 2007 Aug 24;2:24. Epub 2007 Aug 24.

Department of Molecular Virology, Immunology and Medical Genetics and Comprehensive Cancer Center, Ohio State University, OH, USA.

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http://dx.doi.org/10.1186/1747-1028-2-24DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2075490PMC
August 2007

Haploinsufficiency of the Hmga1 gene causes cardiac hypertrophy and myelo-lymphoproliferative disorders in mice.

Cancer Res 2006 Mar;66(5):2536-43

Istituto di Endocrinologia ed Oncologia Sperimentale del Consiglio Nazionale delle Ricerche c/o Dipartimento di Biologia e Patologia Cellulare e Molecolare, Università di Napoli Federico II, Italy.

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http://dx.doi.org/10.1158/0008-5472.CAN-05-1889DOI Listing
March 2006

HMGA1 protein expression sensitizes cells to cisplatin-induced cell death.

Oncogene 2005 Oct;24(45):6809-19

Kimmel Cancer Center, Jefferson Medical College, Philadelphia, PA 19107, USA.

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http://dx.doi.org/10.1038/sj.onc.1208831DOI Listing
October 2005

Reduced E-cadherin expression contributes to the loss of p27kip1-mediated mechanism of contact inhibition in thyroid anaplastic carcinomas.

Carcinogenesis 2005 Jun 17;26(6):1021-34. Epub 2005 Feb 17.

Dipartimento di Biologia e Patologia Cellulare e Molecolare L.Califano Facoltà di Medicina e Chirurgia, Università Federico II, via S. Pansini 5, 80131, Napoli, Italy.

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http://academic.oup.com/carcin/article/26/6/1021/2390852/Red
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http://dx.doi.org/10.1093/carcin/bgi050DOI Listing
June 2005

Transgenic mice overexpressing the wild-type form of the HMGA1 gene develop mixed growth hormone/prolactin cell pituitary adenomas and natural killer cell lymphomas.

Oncogene 2005 May;24(21):3427-35

Istituto di Endocrinologia ed Oncologia Sperimentale del CNR c/o Dipartimento di Biologia e Patologia Cellulare e Molecolare, Università di Napoli Federico II, 80131 Naples, Italy.

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http://dx.doi.org/10.1038/sj.onc.1208501DOI Listing
May 2005

p27(Kip1)-stathmin interaction influences sarcoma cell migration and invasion.

Cancer Cell 2005 Jan;7(1):51-63

Oncologia Sperimentale 2, Centro di Riferimento Oncologico, Istituto Nazionale Tumori, IRCCS, Aviano 33081, Italy.

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http://dx.doi.org/10.1016/j.ccr.2004.11.025DOI Listing
January 2005

Linking inflammation to cell cycle progression.

Curr Pharm Des 2004 ;10(14):1653-66

Divisione di Oncologia Sperimentale 2, Centro di Riferimento Oncologico, Istituto Nazionale Tumori, IRCCS Aviano 33081, Italy.

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http://dx.doi.org/10.2174/1381612043384691DOI Listing
June 2004

Loss of Hmga1 gene function affects embryonic stem cell lympho-hematopoietic differentiation.

FASEB J 2003 Aug 17;17(11):1496-8. Epub 2003 Jun 17.

Dipartimento di Biologia e Patologia Cellulare e Molecolare c/o Centro di Endocrinologia ed Oncologia Sperimentale del CNR, Facoltà di Medicina e Chirurgia, Università degli Studi di Napoli Federico II, via Pansini 5, 80131 Naples, Italy.

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http://dx.doi.org/10.1096/fj.02-0977fjeDOI Listing
August 2003

HMGA1 protein over-expression is a frequent feature of epithelial ovarian carcinomas.

Carcinogenesis 2003 Jul 9;24(7):1191-8. Epub 2003 May 9.

Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, 1020 Locust Street, Philadelphia, PA 19107, USA.

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http://dx.doi.org/10.1093/carcin/bgg075DOI Listing
July 2003

Overexpression of the HMGA2 gene in transgenic mice leads to the onset of pituitary adenomas.

Oncogene 2002 May;21(20):3190-8

Dipartimento di Biologia e Patologia Cellulare e Molecolare, Centro di Endocrinologia ed Oncologia Sperimentale del CNR, Facoltà di Medicina e Chirurgia di Napoli, Federico II Università degli Studi di Napoli, via Pansini 5, 80131 Naples, Italy.

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http://dx.doi.org/10.1038/sj.onc.1205428DOI Listing
May 2002