Gurjit K Hershey

Gurjit K Hershey

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Gurjit K Hershey

Gurjit K Hershey

Publications by authors named "Gurjit K Hershey"

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51Publications

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Environmental exposures and mechanisms in allergy and asthma development.

J Clin Invest 2019 Apr 11;129(4):1504-1515. Epub 2019 Feb 11.

Division of Asthma Research, Cincinnati Children's Medical Center, Cincinnati, Ohio, USA.

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https://www.jci.org/articles/view/124612
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http://dx.doi.org/10.1172/JCI124612DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436881PMC
April 2019

GENEASE: real time bioinformatics tool for multi-omics and disease ontology exploration, analysis and visualization.

Bioinformatics 2018 09;34(18):3160-3168

Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH, USA.

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http://dx.doi.org/10.1093/bioinformatics/bty182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137982PMC
September 2018

Contribution of an impaired epithelial barrier to the atopic march.

Ann Allergy Asthma Immunol 2018 Feb;120(2):118-119

Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio. Electronic address:

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http://dx.doi.org/10.1016/j.anai.2017.11.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033259PMC
February 2018

Evaluation of Fellows' CrossTalk Effectiveness in Promoting Transdisciplinary Networking and Research.

J Pediatr 2017 02 11;181:5-6.e3. Epub 2016 Nov 11.

Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

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http://dx.doi.org/10.1016/j.jpeds.2016.10.063DOI Listing
February 2017

Fungal Exposure and Asthma: IgE and Non-IgE-Mediated Mechanisms.

Curr Allergy Asthma Rep 2016 Nov;16(12):86

Division of Asthma Research, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave., MLC 7037, Cincinnati, OH, 45229, USA.

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http://dx.doi.org/10.1007/s11882-016-0667-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156787PMC
November 2016

Intratracheal myriocin enhances allergen-induced Th2 inflammation and airway hyper-responsiveness.

Immun Inflamm Dis 2016 Sep 2;4(3):248-62. Epub 2016 Jun 2.

Division of Allergy and ImmunologyCincinnati Children's Hospital Medical CenterCincinnatiOhioUSA; Department of PediatricsUniversity of CincinnatiCincinnatiOhioUSA.

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http://dx.doi.org/10.1002/iid3.110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893390PMC
September 2016

Air pollution and allergic diseases.

Curr Opin Pediatr 2015 Dec;27(6):724-35

aDivision of Asthma Research bDivision of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.

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http://dx.doi.org/10.1097/MOP.0000000000000286DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665644PMC
December 2015

Differential effects of rapamycin and dexamethasone in mouse models of established allergic asthma.

PLoS One 2013 17;8(1):e54426. Epub 2013 Jan 17.

Division of Pulmonary Biology, Department of Pediatrics, Cincinnati Children's Hospital, University of Cincinnati School of Medicine, Cincinnati, Ohio, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0054426PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547928PMC
July 2013

Traffic-related air pollution exposure in the first year of life and behavioral scores at 7 years of age.

Environ Health Perspect 2013 Jun 21;121(6):731-6. Epub 2013 May 21.

Division of General and Community Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.

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http://dx.doi.org/10.1289/ehp.1205555DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672910PMC
June 2013

AncestrySNPminer: a bioinformatics tool to retrieve and develop ancestry informative SNP panels.

Genomics 2012 Jul 11;100(1):57-63. Epub 2012 May 11.

Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati, Cincinnati, OH 45229, USA.

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http://dx.doi.org/10.1016/j.ygeno.2012.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433799PMC
July 2012

Downregulation of glutathione S-transferase pi in asthma contributes to enhanced oxidative stress.

J Allergy Clin Immunol 2011 Sep 13;128(3):539-48. Epub 2011 May 13.

Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio, USA.

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http://dx.doi.org/10.1016/j.jaci.2011.04.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164907PMC
September 2011

Genetic biomarkers of health-related quality of life in pediatric asthma.

J Pediatr 2011 Jul 15;159(1):21-26.e1. Epub 2011 Feb 15.

Department of Pediatrics, Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.

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http://dx.doi.org/10.1016/j.jpeds.2010.12.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115404PMC
July 2011

Importance of cytokines in murine allergic airway disease and human asthma.

J Immunol 2010 Feb;184(4):1663-74

Department of Medicine, Cincinnati Veterans Affairs Medical Center, Cincinnati, OH 45220, USA.

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http://dx.doi.org/10.4049/jimmunol.0902185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122090PMC
February 2010

Exposure to traffic-related particles and endotoxin during infancy is associated with wheezing at age 3 years.

Am J Respir Crit Care Med 2009 Dec 10;180(11):1068-75. Epub 2009 Sep 10.

Department of Environmental Health, University of Cincinnati College of Medicine, Cincinnati, OH, USA.

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http://dx.doi.org/10.1164/rccm.200808-1307OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2784413PMC
December 2009

IL-13R alpha 2 membrane and soluble isoforms differ in humans and mice.

J Immunol 2009 Dec;183(12):7870-6

Division of Asthma Research, Department of Pediatrics, Cincinnati Children's Hospital Medical Center and University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.

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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.0901028
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http://dx.doi.org/10.4049/jimmunol.0901028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822278PMC
December 2009

Pathogenicity of a disease-associated human IL-4 receptor allele in experimental asthma.

J Exp Med 2009 Sep 21;206(10):2191-204. Epub 2009 Sep 21.

Division of Immunology, Allergy, and Rheumatology, Department of Pediatrics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1084/jem.20091480DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757875PMC
September 2009

Mold exposure during infancy as a predictor of potential asthma development.

Ann Allergy Asthma Immunol 2009 Feb;102(2):131-7

Department of Environmental Health, University of Cincinnati, Cincinnati, Ohio 45267-0056, USA.

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http://dx.doi.org/10.1016/S1081-1206(10)60243-8DOI Listing
February 2009

Matrix metalloproteinase 8 contributes to solubilization of IL-13 receptor alpha2 in vivo.

J Allergy Clin Immunol 2008 Sep 9;122(3):625-32. Epub 2008 Aug 9.

Division of Allergy and Immunology, Institute for Personalized and Predictive Medicine, Children's Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH 45229, USA.

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http://dx.doi.org/10.1016/j.jaci.2008.06.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770158PMC
September 2008

Asthma genetics: personalizing medicine.

J Asthma 2008 May;45(4):257-64

Institute for Personalized and Predictive Medicine and Division of Allergy and Immunology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH 45229, USA.

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http://dx.doi.org/10.1080/02770900801966180DOI Listing
May 2008

Allergen-dependent solubilization of IL-13 receptor alpha2 reveals a novel mechanism to regulate allergy.

J Allergy Clin Immunol 2007 Feb 30;119(2):375-83. Epub 2006 Nov 30.

Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.

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http://dx.doi.org/10.1016/j.jaci.2006.09.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472628PMC
February 2007

Allergy-driven alternative splicing of IL-13 receptor alpha2 yields distinct membrane and soluble forms.

J Immunol 2006 Dec;177(11):7905-12

Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center and Department of Pediatrics, University of Cincinnati College of Medicine, 3333 Burnet Avenue, Cincinnati, OH 45229, USA.

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http://dx.doi.org/10.4049/jimmunol.177.11.7905DOI Listing
December 2006

Diisocyanate asthma and gene-environment interactions with IL4RA, CD-14, and IL-13 genes.

Ann Allergy Asthma Immunol 2006 Dec;97(6):800-6

Department of Internal Medicine, Division of Immunology, University of Cincinnati Medical Center, Cincinnati, Ohio, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S108112061060972
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http://dx.doi.org/10.1016/S1081-1206(10)60972-6DOI Listing
December 2006

Analysis of short-term influences of ambient aeroallergens on pediatric asthma hospital visits.

Sci Total Environ 2006 Nov 14;370(2-3):330-6. Epub 2006 Aug 14.

Department of Environmental Health, University of Cincinnati, PO Box 670056, Ohio 45267-0056, USA.

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http://dx.doi.org/10.1016/j.scitotenv.2006.06.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2233936PMC
November 2006

Epicutaneous aeroallergen exposure induces systemic TH2 immunity that predisposes to allergic nasal responses.

J Allergy Clin Immunol 2006 Jul 9;118(1):62-9. Epub 2006 Jun 9.

Divisions of Allergy and Immunology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA.

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http://dx.doi.org/10.1016/j.jaci.2006.04.046DOI Listing
July 2006

Level of expression of IL-13R alpha 2 impacts receptor distribution and IL-13 signaling.

J Immunol 2006 Jun;176(12):7495-501

Division of Allergy and Immunology, Department of Pediatrics, Cincinnati Children' Hospital Medical Center, OH 45229, USA

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http://dx.doi.org/10.4049/jimmunol.176.12.7495DOI Listing
June 2006

Altered gene expression profiles in nasal respiratory epithelium reflect stable versus acute childhood asthma.

J Allergy Clin Immunol 2005 Feb;115(2):243-51

Division of Allergy and Immunology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S009167490402688
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http://dx.doi.org/10.1016/j.jaci.2004.10.032DOI Listing
February 2005

Methylation of STAT6 modulates STAT6 phosphorylation, nuclear translocation, and DNA-binding activity.

J Immunol 2004 Jun;172(11):6744-50

Division of Allergy and Immunology, Department of Pediatrics, Cincinnati Children's Hospital, Medical Center, Cincinnati, OH 45229, USA.

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http://dx.doi.org/10.4049/jimmunol.172.11.6744DOI Listing
June 2004

DNA binding activity of cytoplasmic phosphorylated Stat6 is masked by an interaction with a detergent-sensitive factor.

J Biol Chem 2003 Aug 30;278(33):30971-4. Epub 2003 May 30.

Division of Allergy and Immunology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA.

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http://dx.doi.org/10.1074/jbc.M301094200DOI Listing
August 2003

The -159 C-->T polymorphism of CD14 is associated with nonatopic asthma and food allergy.

J Allergy Clin Immunol 2003 Aug;112(2):438-44

Division of Epidemiology and Biostatistics, Department of Environmental Health, University of Cincinnati Medical Center, Ohio, USA.

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http://dx.doi.org/10.1067/mai.2003.1634DOI Listing
August 2003

IL-13 receptors and signaling pathways: an evolving web.

J Allergy Clin Immunol 2003 Apr;111(4):677-90; quiz 691

Division of Allergy, and Immunology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00916749030069
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http://dx.doi.org/10.1067/mai.2003.1333DOI Listing
April 2003

Analysis of the life cycle of stat6. Continuous cycling of STAT6 is required for IL-4 signaling.

J Biol Chem 2002 Sep 16;277(39):36563-9. Epub 2002 Jul 16.

Division of Allergy and Immunology, Department of Pediatrics, Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA.

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http://dx.doi.org/10.1074/jbc.M200986200DOI Listing
September 2002

V75R576 IL-4 receptor alpha is associated with allergic asthma and enhanced IL-4 receptor function.

J Immunol 2002 Aug;169(3):1604-10

Division of Allergy and Immunology, Department of Pediatrics, Children's Hospital Medical Center, Cincinnati, OH 45229, USA.

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http://dx.doi.org/10.4049/jimmunol.169.3.1604DOI Listing
August 2002

A novel mechanism by which interferon-gamma can regulate interleukin (IL)-13 responses. Evidence for intracellular stores of IL-13 receptor alpha -2 and their rapid mobilization by interferon-gamma.

J Biol Chem 2002 Mar 10;277(12):10387-93. Epub 2002 Jan 10.

Division of Allergy and Immunology, Department of Pediatrics, Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M108109200
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http://dx.doi.org/10.1074/jbc.M108109200DOI Listing
March 2002