Gurdyal S Besra

Gurdyal S Besra

UNVERIFIED PROFILE

Are you Gurdyal S Besra?   Register this Author

Register author
Gurdyal S Besra

Gurdyal S Besra

Publications by authors named "Gurdyal S Besra"

Are you Gurdyal S Besra?   Register this Author

100Publications

3264Reads

41Profile Views

Promotion or Suppression of Murine Intestinal Polyp Development by iNKT Cell Directed Immunotherapy.

Front Immunol 2019 1;10:352. Epub 2019 Mar 1.

Department of Microbiology and Immunology, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fimmu.2019.00352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405695PMC
May 2020

Ligand-dependent downregulation of MR1 cell surface expression.

Proc Natl Acad Sci U S A 2020 May 27;117(19):10465-10475. Epub 2020 Apr 27.

MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.2003136117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229755PMC
May 2020

Cryo-EM snapshots of mycobacterial arabinosyltransferase complex EmbB-AcpM.

Protein Cell 2020 May 3. Epub 2020 May 3.

State Key Laboratory of Medicinal Chemical Biology, College of Life Sciences and College of Pharmacy, Nankai University, Tianjin, 300353, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s13238-020-00726-6DOI Listing
May 2020

Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol.

Science 2020 Apr 23. Epub 2020 Apr 23.

Shanghai Institute for Advanced Immunochemical Studies, iHuman Institute, School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.aba9102DOI Listing
April 2020

Targeting mitochondrial dysfunction in MAIT cells limits IL-17 production in obesity.

Cell Mol Immunol 2020 Feb 27. Epub 2020 Feb 27.

Human Health Institute, Department of Biology, Maynooth University, Maynooth, County Kildare, Ireland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41423-020-0375-1DOI Listing
February 2020

Utilisation of the Prestwick Chemical Library to identify drugs that inhibit the growth of mycobacteria.

PLoS One 2019 12;14(3):e0213713. Epub 2019 Mar 12.

Institute of Microbiology and Infection, School of Biosciences, University of Birmingham, Birmingham, United Kingdom.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0213713PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414029PMC
December 2019

The hydrolase LpqI primes mycobacterial peptidoglycan recycling.

Nat Commun 2019 06 14;10(1):2647. Epub 2019 Jun 14.

Institute of Microbiology and Infection, School of Biological Sciences, University of Birmingham, Birmingham, B15 2TT, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-019-10586-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572805PMC
June 2019

Crystal structure of the TreS:Pep2 complex, initiating α-glucan synthesis in the GlgE pathway of mycobacteria.

J Biol Chem 2019 05 15;294(18):7348-7359. Epub 2019 Mar 15.

From the Institute of Microbiology & Infection, School of Biosciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.RA118.004297DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509496PMC
May 2019

Crystal structure of Mycobacterium tuberculosis FadB2 implicated in mycobacterial β-oxidation.

Acta Crystallogr D Struct Biol 2019 Jan 8;75(Pt 1):101-108. Epub 2019 Jan 8.

School of Biosciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, England.

View Article

Download full-text PDF

Source
http://scripts.iucr.org/cgi-bin/paper?S2059798318017242
Publisher Site
http://dx.doi.org/10.1107/S2059798318017242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333283PMC
January 2019

Identification of novel benzothiopyranone compounds against Mycobacterium tuberculosis through scaffold morphing from benzothiazinones.

Eur J Med Chem 2018 Dec 17;160:157-170. Epub 2018 Sep 17.

Beijing Key Laboratory of Drug Resistance Tuberculosis Research, Department of Pharmacology, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing Chest Hospital, Capital Medical University, 97 Ma Chang Street, Beijing, 101149, PR China. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S02235234183081
Publisher Site
http://dx.doi.org/10.1016/j.ejmech.2018.09.042DOI Listing
December 2018

Mycobacterial cell wall biosynthesis: a multifaceted antibiotic target.

Parasitology 2018 02 15;145(2):116-133. Epub 2016 Dec 15.

Institute of Microbiology and Infection,School of Biosciences,University of Birmingham,Edgbaston,Birmingham B15 2TT,UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/S0031182016002377DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964476PMC
February 2018

Colworth prize lecture 2016: exploiting new biological targets from a whole-cell phenotypic screening campaign for TB drug discovery.

Microbiology 2017 Oct 12;163(10):1385-1388. Epub 2017 Sep 12.

Institute of Microbiology and Infection, School of Biosciences, University of Birmingham, Edgbaston, Birmingham, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1099/mic.0.000522DOI Listing
October 2017

Structural determination of lipid antigens captured at the CD1d-T-cell receptor interface.

Proc Natl Acad Sci U S A 2017 08 17;114(31):8348-8353. Epub 2017 Jul 17.

Department of Medicine, Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1705882114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547638PMC
August 2017

Identification of a Desaturase Involved in Mycolic Acid Biosynthesis in Mycobacterium smegmatis.

PLoS One 2016 14;11(10):e0164253. Epub 2016 Oct 14.

School of Biosciences and Institute of Microbiology and Infection, University of Birmingham, Edgbaston, Birmingham, B15 2TT, United Kingdom.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0164253PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065219PMC
May 2017

The role of hydrophobicity in tuberculosis evolution and pathogenicity.

Sci Rep 2017 05 2;7(1):1315. Epub 2017 May 2.

Institute of Microbiology and Infection, School of Biosciences, University of Birmingham, Edgbaston, Birmingham, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-017-01501-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431016PMC
May 2017

CD1d-mediated activation of group 3 innate lymphoid cells drives IL-22 production.

EMBO Rep 2017 01 31;18(1):39-47. Epub 2016 Oct 31.

The Peter Gorer Department of Immunobiology, King's College London, London, UK

View Article

Download full-text PDF

Source
http://dx.doi.org/10.15252/embr.201642412DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5210076PMC
January 2017

Disruption of Mycobacterial AftB Results in Complete Loss of Terminal β(1 → 2) Arabinofuranose Residues of Lipoarabinomannan.

ACS Chem Biol 2017 01 5;12(1):183-190. Epub 2016 Dec 5.

School of Biosciences, Institute of Microbiology and Infection, University of Birmingham , Edgbaston, B15 2TT Birmingham, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acschembio.6b00898DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259755PMC
January 2017

Assembly of the Mycobacterial Cell Wall.

Annu Rev Microbiol 2015 ;69:405-23

School of Biosciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom; email:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1146/annurev-micro-091014-104121DOI Listing
June 2016

Non-glycosidic compounds can stimulate both human and mouse iNKT cells.

Eur J Immunol 2016 05 1;46(5):1224-34. Epub 2016 Mar 1.

MRC Human Immunology Unit, Radcliffe Department of Medicine, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/eji.201546114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913735PMC
May 2016

MKAN27435 is required for the biosynthesis of higher subclasses of lipooligosaccharides in Mycobacterium kansasii.

PLoS One 2015 20;10(3):e0122804. Epub 2015 Apr 20.

School of Biosciences and Institute of Microbiology and Infection, University of Birmingham, Edgbaston, Birmingham, B15 2TT, United Kingdom.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0122804PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403928PMC
February 2016

The actin cytoskeleton modulates the activation of iNKT cells by segregating CD1d nanoclusters on antigen-presenting cells.

Proc Natl Acad Sci U S A 2016 Feb 21;113(6):E772-81. Epub 2016 Jan 21.

ICFO-Institut de Ciencies Fotoniques, The Barcelona Institute of Science and Technology, 08860 Barcelona, Spain; Institució Catalana de Recerca i Estudis Avançats (ICREA), 08010 Barcelona, Spain

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1514530113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760795PMC
February 2016

Atypical natural killer T-cell receptor recognition of CD1d-lipid antigens.

Nat Commun 2016 Feb 15;7:10570. Epub 2016 Feb 15.

Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria 3000, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncomms10570DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756352PMC
February 2016

"Endocytic pH regulates cell surface localization of glycolipid antigen loaded CD1d complexes".

Chem Phys Lipids 2016 Jan 6;194:49-57. Epub 2015 Nov 6.

Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Department of Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.chemphyslip.2015.10.006DOI Listing
January 2016

Antigen Specificity of Type I NKT Cells Is Governed by TCR β-Chain Diversity.

J Immunol 2015 Nov 30;195(10):4604-14. Epub 2015 Sep 30.

Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, Victoria 3010, Australia; Australian Research Council Centre of Excellence in Advanced Molecular Imaging, University of Melbourne, Parkville, Victoria 3010, Australia;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1501222DOI Listing
November 2015

Mycolic acids: deciphering and targeting the Achilles' heel of the tubercle bacillus.

Mol Microbiol 2015 Oct 30;98(1):7-16. Epub 2015 Jul 30.

School of Biosciences and Institute of Microbiology and Infection, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/mmi.13101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949712PMC
October 2015

Endocytic pH regulates cell surface localization of glycolipid antigen loaded CD1d complexes.

Chem Phys Lipids 2015 Oct 22;191:75-83. Epub 2015 Aug 22.

Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Department of Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.chemphyslip.2015.08.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633376PMC
October 2015

Identification of a Potent Microbial Lipid Antigen for Diverse NKT Cells.

J Immunol 2015 Sep 7;195(6):2540-51. Epub 2015 Aug 7.

Division of Rheumatology, Immunology, and Allergy, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1501019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030721PMC
September 2015

A Novel Glycolipid Antigen for NKT Cells That Preferentially Induces IFN-γ Production.

J Immunol 2015 Aug 15;195(3):924-33. Epub 2015 Jun 15.

Division of Developmental Immunology, La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037; Division of Biological Sciences, University of California, San Diego, La Jolla, CA 92037;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1500070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506857PMC
August 2015

A Subset of CD8αβ+ Invariant NKT Cells in a Humanized Mouse Model.

J Immunol 2015 Aug 8;195(4):1459-69. Epub 2015 Jul 8.

Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1500574DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530047PMC
August 2015

Ancient mycobacterial lipids: Key reference biomarkers in charting the evolution of tuberculosis.

Tuberculosis (Edinb) 2015 Jun 12;95 Suppl 1:S133-9. Epub 2015 Feb 12.

Centres for Clinical Microbiology and the History of Medicine, University College London, London, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tube.2015.02.009DOI Listing
June 2015

7000 year-old tuberculosis cases from Hungary - Osteological and biomolecular evidence.

Tuberculosis (Edinb) 2015 Jun 12;95 Suppl 1:S13-7. Epub 2015 Feb 12.

Department of Biological Anthropology, University of Szeged, Szeged, Hungary. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tube.2015.02.007DOI Listing
June 2015

Morphological and biomolecular evidence for tuberculosis in 8th century AD skeletons from Bélmegyer-Csömöki domb, Hungary.

Tuberculosis (Edinb) 2015 Jun 13;95 Suppl 1:S35-41. Epub 2015 Feb 13.

Department of Biological Anthropology, University of Szeged, Szeged, Hungary. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tube.2015.02.032DOI Listing
June 2015

Ancient DNA analysis - An established technique in charting the evolution of tuberculosis and leprosy.

Tuberculosis (Edinb) 2015 Jun 13;95 Suppl 1:S140-4. Epub 2015 Feb 13.

Institute of Microbiology and Infection, School of Biosciences, University of Birmingham, Edgbaston, Birmingham, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tube.2015.02.020DOI Listing
June 2015

Lipid biomarkers provide evolutionary signposts for the oldest known cases of tuberculosis.

Tuberculosis (Edinb) 2015 Jun 25;95 Suppl 1:S127-32. Epub 2015 Feb 25.

Institute of Microbiology and Infection, School of Biosciences, University of Birmingham, Edgbaston, Birmingham, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tube.2015.02.013DOI Listing
June 2015

Human tuberculosis predates domestication in ancient Syria.

Tuberculosis (Edinb) 2015 Jun 26;95 Suppl 1:S4-S12. Epub 2015 Feb 26.

Laboratoire d'Anthropologie biologique Paul Broca, Ecole Pratique des Hautes Etudes, Paris, France; De la Préhistoire à l'Actuel: Culture, Environnement, Anthropologie (PACEA, UMR 5199, CNRS, Université de Bordeaux, Ministère de la Culture et de la Communication), Allée Geoffroy St Hilaire, CS 50023, 33615 Pessac Cedex, France; Department of Anthropology, University of Western Ontario, London, Canada. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tube.2015.02.001DOI Listing
June 2015

A migration-driven model for the historical spread of leprosy in medieval Eastern and Central Europe.

Infect Genet Evol 2015 Apr 11;31:250-6. Epub 2015 Feb 11.

Centre for Clinical Microbiology, Division of Infection and Immunity, University College London, UK; Department of Anatomy and Anthropology Sackler Medical School, Tel Aviv University, Israel.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.meegid.2015.02.001DOI Listing
April 2015

In contrast to other species, α-Galactosylceramide (α-GalCer) is not an immunostimulatory NKT cell agonist in horses.

Dev Comp Immunol 2015 Mar 10;49(1):49-58. Epub 2014 Nov 10.

Department of Veterinary Microbiology and Pathology, Washington State University, College of Veterinary Medicine, P.O. Box 647040, Pullman, WA 99164-7040, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.dci.2014.11.005DOI Listing
March 2015

Osteological and biomolecular evidence of a 7000-year-old case of hypertrophic pulmonary osteopathy secondary to tuberculosis from neolithic hungary.

PLoS One 2013 30;8(10):e78252. Epub 2013 Oct 30.

Archaeology, University of Edinburgh, Edinburgh, Scotland, United Kingdom ; Department of Biological Anthropology, University of Szeged, Szeged, Hungary.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0078252PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813517PMC
February 2015

Gal-3 regulates the capacity of dendritic cells to promote NKT-cell-induced liver injury.

Eur J Immunol 2015 Feb 27;45(2):531-43. Epub 2014 Nov 27.

Centre for Molecular Medicine and Stem Cell Research, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/eji.201444849DOI Listing
February 2015

Cytotoxic mediators in paradoxical HIV-tuberculosis immune reconstitution inflammatory syndrome.

J Immunol 2015 Feb 14;194(4):1748-54. Epub 2015 Jan 14.

Clinical Infectious Diseases Research Initiative, University of Cape Town, Cape Town, 7925 South Africa; Department of Medicine, University of Cape Town, Cape Town, 7925 South Africa; Medical Research Council National Institute for Medical Research, London NW7 1AA, United Kingdom; Division of Medicine, Imperial College London, London W2 1PG, United Kingdom;

View Article

Download full-text PDF

Source
http://www.jimmunol.org/lookup/doi/10.4049/jimmunol.1402105
Publisher Site
http://dx.doi.org/10.4049/jimmunol.1402105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319311PMC
February 2015

The C-type lectin receptor CLECSF8/CLEC4D is a key component of anti-mycobacterial immunity.

Cell Host Microbe 2015 Feb;17(2):252-9

Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, UK; Division of Immunology, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, 792 Cape Town, South Africa. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.chom.2015.01.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334100PMC
February 2015

Gram-positive bacterial lipoglycans based on a glycosylated diacylglycerol lipid anchor are microbe-associated molecular patterns recognized by TLR2.

PLoS One 2013 21;8(11):e81593. Epub 2013 Nov 21.

CNRS; IPBS (Institut de Pharmacologie et de Biologie Structurale); 205 route de Narbonne, F-31077 Toulouse, France ; Université de Toulouse; UPS; IPBS; F-31077 Toulouse, France.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0081593PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836763PMC
January 2015

Essential role for autophagy during invariant NKT cell development.

Proc Natl Acad Sci U S A 2014 Dec 15;111(52):E5678-87. Epub 2014 Dec 15.

Medical Research Council Human Immunology Unit, Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Headington, Oxford OX3 9DS, United Kingdom;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1413935112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284579PMC
December 2014

Selectfluor and NFSI exo-glycal fluorination strategies applied to the enhancement of the binding affinity of galactofuranosyltransferase GlfT2 inhibitors.

Chemistry 2014 Nov 24;20(46):15208-15. Epub 2014 Sep 24.

University of Namur (UNamur), Département de Chimie, Laboratoire de Chimie Bio-Organique rue de Bruxelles 61, B-5000 Namur (Belgium), Fax: (+32) 81-72-45-17.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/chem.201404180DOI Listing
November 2014

Activation of iNKT cells by a distinct constituent of the endogenous glucosylceramide fraction.

Proc Natl Acad Sci U S A 2014 Sep 2;111(37):13433-8. Epub 2014 Sep 2.

Department of Medicine, Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1415357111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169973PMC
September 2014

Genetics of Mycobacterial Arabinogalactan and Lipoarabinomannan Assembly.

Microbiol Spectr 2014 Aug;2(4):MGM2-0013-2013

School of Biosciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/microbiolspec.MGM2-0013-2013DOI Listing
August 2014

Expression of CD1c enhances human invariant NKT cell activation by α-GalCer.

Cancer Immun 2013 10;13. Epub 2013 May 10.

Department of Medical Microbiology and Immunology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53706, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3721260PMC
May 2014

Discrimination between bacterial phenotypes using glyco-nanoparticles and the impact of polymer coating on detection readouts.

J Mater Chem B 2014 Mar 4;2(11):1490-1498. Epub 2014 Feb 4.

Department of Chemistry, University of Warwick, Coventry, CV4 7AL, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/c3tb21821jDOI Listing
March 2014

Benzothiazinones mediate killing of Corynebacterineae by blocking decaprenyl phosphate recycling involved in cell wall biosynthesis.

J Biol Chem 2014 Feb 20;289(9):6177-87. Epub 2014 Jan 20.

From the School of Biosciences, Institute of Microbiology and Infection, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom and.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M113.522623DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937683PMC
February 2014

Saposins modulate human invariant Natural Killer T cells self-reactivity and facilitate lipid exchange with CD1d molecules during antigen presentation.

Proc Natl Acad Sci U S A 2013 Dec 18;110(49):E4753-61. Epub 2013 Nov 18.

Medical Research Council Human Immunology Unit, Radcliffe Department of Medicine, Medical Research Council Weatherall Institute of Molecular Medicine, University of Oxford, Headington, Oxford OX3 9DS, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1310050110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856826PMC
December 2013

IpsA, a novel LacI-type regulator, is required for inositol-derived lipid formation in Corynebacteria and Mycobacteria.

BMC Biol 2013 Dec 30;11:122. Epub 2013 Dec 30.

Institut für Bio- und Geowissenschaften, IBG-1: Biotechnologie, Forschungszentrum Jülich, 52425 Jülich, Germany.

View Article

Download full-text PDF

Source
http://bmcbiol.biomedcentral.com/articles/10.1186/1741-7007-
Publisher Site
http://dx.doi.org/10.1186/1741-7007-11-122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899939PMC
December 2013

Synthesis of α-glucan in mycobacteria involves a hetero-octameric complex of trehalose synthase TreS and Maltokinase Pep2.

ACS Chem Biol 2013 Oct 13;8(10):2245-55. Epub 2013 Aug 13.

School of Biosciences, University of Birmingham , Edgbaston, Birmingham B15 2TT, U.K.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/cb400508kDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805332PMC
October 2013

β-mannosylceramide activates type I natural killer t cells to induce tumor immunity without inducing long-term functional anergy.

Clin Cancer Res 2013 Aug 26;19(16):4404-11. Epub 2013 Jun 26.

Vaccine Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-12-2169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819527PMC
August 2013