Publications by authors named "Guotai Xu"

12Publications

ARID1A determines luminal identity and therapeutic response in estrogen-receptor-positive breast cancer.

Authors:
Guotai Xu Sagar Chhangawala Emiliano Cocco Pedram Razavi Yanyan Cai Jordan E Otto Lorenzo Ferrando Pier Selenica Erik Ladewig Carmen Chan Arnaud Da Cruz Paula Matthew Witkin Yuanming Cheng Jane Park Cristian Serna-Tamayo HuiYong Zhao Fan Wu Mirna Sallaku Xuan Qu Alison Zhao Clayton K Collings Andrew R D'Avino Komal Jhaveri Richard Koche Ross L Levine Jorge S Reis-Filho Cigall Kadoch Maurizio Scaltriti Christina S Leslie José Baselga Eneda Toska

Nat Genet 2020 02 13;52(2):198-207. Epub 2020 Jan 13.

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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February 2020

Double mutations in cis increase oncogenicity and sensitivity to PI3Kα inhibitors.

Authors:
Neil Vasan Pedram Razavi Jared L Johnson Hong Shao Hardik Shah Alesia Antoine Erik Ladewig Alexander Gorelick Ting-Yu Lin Eneda Toska Guotai Xu Abiha Kazmi Matthew T Chang Barry S Taylor Maura N Dickler Komal Jhaveri Sarat Chandarlapaty Raul Rabadan Ed Reznik Melissa L Smith Robert Sebra Frauke Schimmoller Timothy R Wilson Lori S Friedman Lewis C Cantley Maurizio Scaltriti José Baselga

Science 2019 11;366(6466):714-723

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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November 2019

PI3K Inhibition Activates SGK1 via a Feedback Loop to Promote Chromatin-Based Regulation of ER-Dependent Gene Expression.

Authors:
Eneda Toska Pau Castel Sagar Chhangawala Amaia Arruabarrena-Aristorena Carmen Chan Vasilis C Hristidis Emiliano Cocco Mirna Sallaku Guotai Xu Jane Park Gerard Minuesa Sophie G Shifman Nicholas D Socci Richard Koche Christina S Leslie Maurizio Scaltriti José Baselga

Cell Rep 2019 04;27(1):294-306.e5

Human Oncology and Pathogenesis Program (HOPP), Memorial Sloan Kettering Cancer Center, 1275 York Avenue, Box 20, New York, NY 10065, USA; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Research & Development Oncology, AstraZeneca Pharmaceuticals, Gaithersburg, MD 20878, USA. Electronic address:

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April 2019

The Genomic Landscape of Endocrine-Resistant Advanced Breast Cancers.

Authors:
Pedram Razavi Matthew T Chang Guotai Xu Chaitanya Bandlamudi Dara S Ross Neil Vasan Yanyan Cai Craig M Bielski Mark T A Donoghue Philip Jonsson Alexander Penson Ronglai Shen Fresia Pareja Ritika Kundra Sumit Middha Michael L Cheng Ahmet Zehir Cyriac Kandoth Ruchi Patel Kety Huberman Lillian M Smyth Komal Jhaveri Shanu Modi Tiffany A Traina Chau Dang Wen Zhang Britta Weigelt Bob T Li Marc Ladanyi David M Hyman Nikolaus Schultz Mark E Robson Clifford Hudis Edi Brogi Agnes Viale Larry Norton Maura N Dickler Michael F Berger Christine A Iacobuzio-Donahue Sarat Chandarlapaty Maurizio Scaltriti Jorge S Reis-Filho David B Solit Barry S Taylor José Baselga

Cancer Cell 2018 09;34(3):427-438.e6

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Electronic address:

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September 2018

[PRELIMINARY APPLICATION OF VIRTUAL PREOPERATIVE RECONSTRUCTION PLANNING IN Pilon FRACTURES].

Authors:
Wang Xiaoping Zhantu Wei Jian Huang Luyao Chen Shiqiang Hu Weiwei Wu Yumin Tu Sheng Guo Guotai Xu Zhicheng Deng

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2016 Jan;30(1):44-9

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January 2016

HELB Is a Feedback Inhibitor of DNA End Resection.

Authors:
Ján Tkáč Guotai Xu Hemanta Adhikary Jordan T F Young David Gallo Cristina Escribano-Díaz Jana Krietsch Alexandre Orthwein Meagan Munro Wendy Sol Abdallah Al-Hakim Zhen-Yuan Lin Jos Jonkers Piet Borst Grant W Brown Anne-Claude Gingras Sven Rottenberg Jean-Yves Masson Daniel Durocher

Mol Cell 2016 Feb 7;61(3):405-418. Epub 2016 Jan 7.

Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, 600 University Avenue, Toronto, ON M5G 1X5, Canada; Department of Molecular Genetics, University of Toronto, ON M5S 1A8, Canada. Electronic address:

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February 2016

Subunit composition of VRAC channels determines substrate specificity and cellular resistance to Pt-based anti-cancer drugs.

Authors:
Rosa Planells-Cases Darius Lutter Charlotte Guyader Nora M Gerhards Florian Ullrich Deborah A Elger Asli Kucukosmanoglu Guotai Xu Felizia K Voss S Momsen Reincke Tobias Stauber Vincent A Blomen Daniel J Vis Lodewyk F Wessels Thijn R Brummelkamp Piet Borst Sven Rottenberg Thomas J Jentsch

EMBO J 2015 Dec 3;34(24):2993-3008. Epub 2015 Nov 3.

Leibniz-Institut für Molekulare Pharmakologie (FMP) Max-Delbrück-Centrum für Molekulare Medizin (MDC), Berlin, Germany NeuroCure Cluster of Excellence, Charité Universitätsmedizin, Berlin, Germany

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December 2015

CopywriteR: DNA copy number detection from off-target sequence data.

Authors:
Thomas Kuilman Arno Velds Kristel Kemper Marco Ranzani Lorenzo Bombardelli Marlous Hoogstraat Ekaterina Nevedomskaya Guotai Xu Julian de Ruiter Martijn P Lolkema Bauke Ylstra Jos Jonkers Sven Rottenberg Lodewyk F Wessels David J Adams Daniel S Peeper Oscar Krijgsman

Genome Biol 2015 Feb 27;16:49. Epub 2015 Feb 27.

Division of Molecular Oncology, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands.

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February 2015

REV7 counteracts DNA double-strand break resection and affects PARP inhibition.

Authors:
Guotai Xu J Ross Chapman Inger Brandsma Jingsong Yuan Martin Mistrik Peter Bouwman Jirina Bartkova Ewa Gogola Daniël Warmerdam Marco Barazas Janneke E Jaspers Kenji Watanabe Mark Pieterse Ariena Kersbergen Wendy Sol Patrick H N Celie Philip C Schouten Bram van den Broek Ahmed Salman Marja Nieuwland Iris de Rink Jorma de Ronde Kees Jalink Simon J Boulton Junjie Chen Dik C van Gent Jiri Bartek Jos Jonkers Piet Borst Sven Rottenberg

Nature 2015 May 23;521(7553):541-544. Epub 2015 Mar 23.

Division of Molecular Oncology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066CX Amsterdam, The Netherlands.

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May 2015

BRCA2-deficient sarcomatoid mammary tumors exhibit multidrug resistance.

Authors:
Janneke E Jaspers Wendy Sol Ariena Kersbergen Andreas Schlicker Charlotte Guyader Guotai Xu Lodewyk Wessels Piet Borst Jos Jonkers Sven Rottenberg

Cancer Res 2015 Feb 15;75(4):732-41. Epub 2014 Dec 15.

Division of Molecular Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands. Institute of Animal Pathology, Vetsuisse Faculty, University of Bern, Bern, Switzerland.

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February 2015

Proteomics of genetically engineered mouse mammary tumors identifies fatty acid metabolism members as potential predictive markers for cisplatin resistance.

Authors:
Marc Warmoes Janneke E Jaspers Guotai Xu Bharath K Sampadi Thang V Pham Jaco C Knol Sander R Piersma Epie Boven Jos Jonkers Sven Rottenberg Connie R Jimenez

Mol Cell Proteomics 2013 May 8;12(5):1319-34. Epub 2013 Feb 8.

OncoProteomics Laboratory, Department of Medical Oncology, VU University Medical Center, De Boelelaan 1117, 1081HV Amsterdam, The Netherlands.

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May 2013

Dominant negative STAT3 suppresses the growth and invasion capability of human lung cancer cells.

Authors:
Guotai Xu Cai Zhang Jian Zhang

Mol Med Rep 2009 Sep-Oct;2(5):819-24

School of Pharmaceutical Sciences, Shandong University, Jinan 250012, P.R. China.

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October 2012