Guoping Zhao

Guoping Zhao

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Ligustilide suppresses RANKL-induced osteoclastogenesis and bone resorption via inhibition of RANK expression.

J Cell Biochem 2019 Nov 22;120(11):18667-18677. Epub 2019 Aug 22.

Department of Orthopedics, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.

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http://dx.doi.org/10.1002/jcb.29153DOI Listing
November 2019

Aging-independent and size-dependent genotoxic response induced by titanium dioxide nanoparticles in mammalian cells.

J Environ Sci (China) 2019 Nov 22;85:94-106. Epub 2019 May 22.

Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Chinese Academy of Sciences, Anhui Province Key Laboratory of Environmental Toxicology and Pollution Control Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Anhui 230031, P.R. China; Institutes of Physical Science and Information Technology, Anhui University, Hefei, Anhui 230601, P.R. China. Electronic address:

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http://dx.doi.org/10.1016/j.jes.2019.04.024DOI Listing
November 2019

Radiation induces apoptosis primarily through the intrinsic pathway in mammalian cells.

Cell Signal 2019 Oct 5;62:109337. Epub 2019 Jun 5.

Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Anhui Province Key Laboratory of Environmental Toxicology and Pollution Control Technology, Hefei, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.cellsig.2019.06.002DOI Listing
October 2019

CobB2-mediated Lysine Desuccinylation Regulates Protein Biosynthesis and Carbon Metabolism in .

Mol Cell Proteomics 2019 Oct 23;18(10):2003-2017. Epub 2019 Jul 23.

Key Laboratory of Synthetic Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200032, China

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http://dx.doi.org/10.1074/mcp.RA118.001298DOI Listing
October 2019

Bio-Inspired Balance Control Assistance Can Reduce Metabolic Energy Consumption in Human Walking.

IEEE Trans Neural Syst Rehabil Eng 2019 Sep 12;27(9):1760-1769. Epub 2019 Aug 12.

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http://dx.doi.org/10.1109/TNSRE.2019.2929544DOI Listing
September 2019

HOLMESv2: A CRISPR-Cas12b-Assisted Platform for Nucleic Acid Detection and DNA Methylation Quantitation.

ACS Synth Biol 2019 Sep 30. Epub 2019 Sep 30.

College of Life Sciences , Shanghai Normal University , Shanghai , 200234 , China.

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http://dx.doi.org/10.1021/acssynbio.9b00209DOI Listing
September 2019

Microbes: the hidden giant behind the biogeochemical cycling of elements in the hydrosphere.

Sci China Life Sci 2019 Sep 27. Epub 2019 Sep 27.

Key Laboratory of Synthetic Biology, Institute of Plant Physiology & Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, 200032, China.

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http://dx.doi.org/10.1007/s11427-019-1554-yDOI Listing
September 2019

In vitro and in vivo studies of antiosteosarcoma activities of formononetin.

J Cell Physiol 2019 Aug 20;234(10):17305-17313. Epub 2019 Feb 20.

Department of Orthopaedics Ward, Guilin Peoples' Hospital, Guilin, Guangxi, China.

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http://dx.doi.org/10.1002/jcp.28349DOI Listing
August 2019

Inositol-requiring enzyme 1 alpha endoribonuclease specific inhibitor STF-083010 protects the liver from thioacetamide-induced oxidative stress, inflammation and injury by triggering hepatocyte autophagy.

Int Immunopharmacol 2019 Aug 21;73:261-269. Epub 2019 May 21.

Hepatobiliary Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China. Electronic address:

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http://dx.doi.org/10.1016/j.intimp.2019.04.051DOI Listing
August 2019

Higenamine exerts an antispasmodic effect on cold-induced vasoconstriction by regulating the PI3K/Akt, ROS/α2C-AR and PTK9 pathways independently of the AMPK/eNOS/NO axis.

Exp Ther Med 2019 Aug 10;18(2):1299-1308. Epub 2019 Jun 10.

Scientific Research Center, School of Traditional Chinese Medicine, Jinan University, Guangzhou, Guangdong 510632, P.R. China.

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http://dx.doi.org/10.3892/etm.2019.7656DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601373PMC
August 2019

Efficient circular gene knockout system for Burkholderiales strain DSM 7029 and Mycobacterium smegmatis mc2 155.

Acta Biochim Biophys Sin (Shanghai) 2019 Jul;51(7):697-706

Collaborative Innovation Center for Genetics and Development, State Key Laboratory of Genetic Engineering, Department of Microbiology, School of Life Sciences, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1093/abbs/gmz054DOI Listing
July 2019

Subcellular targets of zinc oxide nanoparticles during the aging process: role of cross-talk between mitochondrial dysfunction and endoplasmic reticulum stress in the genotoxic response.

Toxicol Sci 2019 Jun 7. Epub 2019 Jun 7.

Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Chinese Academy of Sciences; Anhui Province Key Laboratory of Environmental Toxicology and Pollution Control Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Anhui, P. R. China.

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http://dx.doi.org/10.1093/toxsci/kfz132DOI Listing
June 2019

Anti-cancer targets of formononetin and molecular mechanisms in osteosarcoma: Findings of bioinformatic and experimental assays.

J Cell Mol Med 2019 May 15;23(5):3505-3511. Epub 2019 Mar 15.

Orthopeadics Ward, Guilin Peoples' Hospital, Guilin, Guangxi, China.

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http://dx.doi.org/10.1111/jcmm.14248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484398PMC
May 2019

Reprogrammable CRISPR/dCas9-based recruitment of DNMT1 for site-specific DNA demethylation and gene regulation.

Cell Discov 2019 16;5:22. Epub 2019 Apr 16.

1Carson International Cancer Center, Shenzhen University School of Medicine, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, 518039 China.

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http://dx.doi.org/10.1038/s41421-019-0090-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465405PMC
April 2019

CRISPR/ddCas12a-based programmable and accurate gene regulation.

Cell Discov 2019 12;5:15. Epub 2019 Mar 12.

5College of Life and Environment Sciences, Shanghai Normal University, 200234 Shanghai, China.

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http://www.nature.com/articles/s41421-019-0085-y
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http://dx.doi.org/10.1038/s41421-019-0085-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411887PMC
March 2019

The inhibition effect of cold atmospheric plasma-activated media in cutaneous squamous carcinoma cells.

Future Oncol 2019 Feb 16;15(5):495-505. Epub 2019 Jan 16.

Department of Dermatology, The First Affiliated Hospital, Anhui Medical University, Hefei, Anhui, PR China.

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http://dx.doi.org/10.2217/fon-2018-0419DOI Listing
February 2019

Correlation of Gut Microbiome Between ASD Children and Mothers and Potential Biomarkers for Risk Assessment.

Genomics Proteomics Bioinformatics 2019 02 23;17(1):26-38. Epub 2019 Apr 23.

CAS Key Laboratory of Synthetic Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.

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http://dx.doi.org/10.1016/j.gpb.2019.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520911PMC
February 2019

iCatch: a new strategy for capturing large DNA fragments using homing endonucleases.

Acta Biochim Biophys Sin (Shanghai) 2019 Jan;51(1):97-103

Carson International Cancer Center, Shenzhen University School of Medicine, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, China.

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http://dx.doi.org/10.1093/abbs/gmy139DOI Listing
January 2019

A single circular chromosome yeast.

Cell Res 2019 Jan 17;29(1):87-89. Epub 2018 Dec 17.

Key Laboratory of Synthetic Biology, CAS Center for Excellence in Molecular Plant Sciences, Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, 200032, Shanghai, China.

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http://dx.doi.org/10.1038/s41422-018-0110-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318310PMC
January 2019

N-(3-oxo-acyl) homoserine lactone induced germ cell apoptosis and suppressed the over-activated RAS/MAPK tumorigenesis via mitochondrial-dependent ROS in C. elegans.

Apoptosis 2018 12;23(11-12):626-640

Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Chinese Academy of Sciences; Anhui Province Key Laboratory of Environmental Toxicology and Pollution Control Technology, Hefei, 230031, Anhui, People's Republic of China.

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http://dx.doi.org/10.1007/s10495-018-1478-3DOI Listing
December 2018

TiO nanoparticles enhance bioaccumulation and toxicity of heavy metals in Caenorhabditis elegans via modification of local concentrations during the sedimentation process.

Ecotoxicol Environ Saf 2018 Oct 4;162:160-169. Epub 2018 Jul 4.

Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Chinese Academy of Sciences, Anhui Province Key Laboratory of Environmental Toxicology and Pollution Control Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Anhui 230031, PR China; Institutes of Physical Science and Information Technology, Anhui University, Hefei, Anhui, 230601, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.ecoenv.2018.06.051DOI Listing
October 2018

Mechanisms involved in the impact of engineered nanomaterials on the joint toxicity with environmental pollutants.

Ecotoxicol Environ Saf 2018 Oct 30;162:92-102. Epub 2018 Jun 30.

Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Chinese Academy of Sciences; Anhui Province Key Laboratory of Environmental Toxicology and Pollution Control Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Anhui 230031, PR China; Institutes of Physical Science and Information Technology, Anhui University, Hefei, Anhui, 230601, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.ecoenv.2018.06.079DOI Listing
October 2018

Disruption of Chromosomal Architecture of cox2 Locus Sensitizes Lung Cancer Cells to Radiotherapy.

Mol Ther 2018 10 8;26(10):2456-2465. Epub 2018 Aug 8.

Institute of Physical Science and Information Technology, Anhui University, Hefei, Anhui 230601, China; Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Anhui 230031, China; Key Laboratory of Environmental Toxicology and Pollution Control Technology of Anhui Province, Hefei, Anhui 230031, China. Electronic address:

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http://dx.doi.org/10.1016/j.ymthe.2018.08.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171098PMC
October 2018

GlnR positive transcriptional regulation of the phosphate-specific transport system pstSCAB in Amycolatopsis mediterranei U32.

Acta Biochim Biophys Sin (Shanghai) 2018 Aug;50(8):757-765

School of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, Shenyang, China.

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http://dx.doi.org/10.1093/abbs/gmy073DOI Listing
August 2018

Assessment of the cytotoxic and mutagenic potential of the Jialu River and adjacent groundwater using human-hamster hybrid cells.

J Environ Sci (China) 2018 Aug 6;70:133-143. Epub 2017 Dec 6.

Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031, China; Key Laboratory of Environmental Toxicology and Pollution Control Technology of Anhui Province, Hefei 230031, China; School of Nuclear Science and Technology, University of Science and Technology of China, Hefei 230026, China. Electronic address:

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http://dx.doi.org/10.1016/j.jes.2017.11.023DOI Listing
August 2018

Creating a functional single-chromosome yeast.

Nature 2018 08 1;560(7718):331-335. Epub 2018 Aug 1.

Key Laboratory of Synthetic Biology, CAS Center for Excellence in Molecular Plant Sciences, Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai, China.

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http://dx.doi.org/10.1038/s41586-018-0382-xDOI Listing
August 2018

Metabolic profiling of corylin in vivo and in vitro.

J Pharm Biomed Anal 2018 Jun 26;155:157-168. Epub 2018 Mar 26.

College of Pharmacy, Jinan University, Guangzhou 510632, PR China; Guangdong Provincial Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, College of Pharmacy, Jinan University, Guangzhou 510632, PR China; Integrated Chinese and Western Medicine Postdoctoral research station, Jinan University, Guangzhou 510632, PR China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S07317085173181
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http://dx.doi.org/10.1016/j.jpba.2018.03.047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6666405PMC
June 2018

Deciphering the late steps of rifamycin biosynthesis.

Nat Commun 2018 06 14;9(1):2342. Epub 2018 Jun 14.

Shandong Provincial Key Laboratory of Synthetic Biology, CAS Key Laboratory of Biofuels, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, Shandong, 266101, China.

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http://www.nature.com/articles/s41467-018-04772-x
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http://dx.doi.org/10.1038/s41467-018-04772-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002545PMC
June 2018

Site-specificity of serine integrase demonstrated by the attB sequence preference of ɸBT1 integrase.

FEBS Lett 2018 04 25;592(8):1389-1399. Epub 2018 Mar 25.

Collaborative Innovation Center for Genetics and Development, State Key Laboratory of Genetic Engineering, Department of Microbiology, School of Life Sciences, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1002/1873-3468.13023DOI Listing
April 2018

Identification of the streptothricin and tunicamycin biosynthetic gene clusters by genome mining in Streptomyces sp. strain fd1-xmd.

Appl Microbiol Biotechnol 2018 Mar 8;102(6):2621-2633. Epub 2018 Feb 8.

Collaborative Innovation Center for Genetics and Development, State Key Laboratory of Genetic Engineering, Department of Microbiology, School of Life Sciences, Fudan University, Shanghai, 200438, People's Republic of China.

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http://dx.doi.org/10.1007/s00253-018-8748-4DOI Listing
March 2018

Insight into the Molecular Mechanism of the Transcriptional Regulation of Operon in .

Front Microbiol 2018 20;9:264. Epub 2018 Feb 20.

CAS Key Laboratory of Synthetic Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.

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http://dx.doi.org/10.3389/fmicb.2018.00264DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826061PMC
February 2018

Small surface antigen variants of HBV associated with responses to telbivudine treatment in chronic hepatitis B patients.

Antivir Ther 2017 1;22(1):43-51. Epub 2016 Sep 1.

CAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.

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http://dx.doi.org/10.3851/IMP3078DOI Listing
January 2018

N-(3-Oxo-acyl)-homoserine lactone induces apoptosis primarily through a mitochondrial pathway in fibroblasts.

Cell Microbiol 2018 01 9;20(1). Epub 2017 Oct 9.

Molecular Targets Program, James Graham Brown Cancer Center, Departments of Medicine, Pharmacology and Toxicology, University of Louisville, Louisville, KY, USA.

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http://dx.doi.org/10.1111/cmi.12787DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729120PMC
January 2018

A feedback regulatory model for RifQ-mediated repression of rifamycin export in Amycolatopsis mediterranei.

Microb Cell Fact 2018 Jan 29;17(1):14. Epub 2018 Jan 29.

CAS Key Laboratory of Synthetic Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 500 Caobao Road, Shanghai, 200233, China.

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http://dx.doi.org/10.1186/s12934-018-0863-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787919PMC
January 2018

dbCRSR: a manually curated database for regulation of cancer radiosensitivity.

Database (Oxford) 2018 01;2018

Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Anhui Province Key Laboratory of Environmental Toxicology and Pollution Control Technology, Hefei, Anhui, People's Republic of China.

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http://dx.doi.org/10.1093/database/bay049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007213PMC
January 2018

TRPA1 and TRPM8 Receptors May Promote Local Vasodilation that Aggravates Oxaliplatin-Induced Peripheral Neuropathy Amenable to 17β-Estradiol Treatment.

Curr Neurovasc Res 2016 ;13(4):309-317

Department of Traditional Chinese Medicine, College of Medicine, Jinan University, Guangzhou, 510630, China.

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October 2017

Morphology engineering of Streptomyces coelicolor M145 by sub-inhibitory concentrations of antibiotics.

Sci Rep 2017 10 16;7(1):13226. Epub 2017 Oct 16.

Collaborative Innovation Center for Genetics and Development, State Key Laboratory of Genetic Engineering, Department of Microbiology, School of Life Sciences, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1038/s41598-017-13493-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643529PMC
October 2017

Amplification of arsenic genotoxicity by TiO nanoparticles in mammalian cells: new insights from physicochemical interactions and mitochondria.

Nanotoxicology 2017 Oct 18;11(8):978-995. Epub 2017 Oct 18.

a Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Hefei Institutes of Physical Science, Chinese Academy of Sciences ; Anhui Province Key Laboratory of Environmental Toxicology and Pollution Control Technology , Hefei , Anhui , PR China.

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https://www.tandfonline.com/doi/full/10.1080/17435390.2017.1
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http://dx.doi.org/10.1080/17435390.2017.1388861DOI Listing
October 2017

Conjugation of ϕBT1-derived integrative plasmid pDZL802 in Amycolatopsis mediterranei U32.

Bioengineered 2017 Sep 3;8(5):549-554. Epub 2017 Jan 3.

a State Key Laboratory of Genetic Engineering, Department of Microbiology and Microbial Engineering , School of Life Sciences, Fudan University , Shanghai , China.

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http://dx.doi.org/10.1080/21655979.2016.1270808DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639847PMC
September 2017

Locomotor Sub-functions for Control of Assistive Wearable Robots.

Front Neurorobot 2017 4;11:44. Epub 2017 Sep 4.

Lauflabor Locomotion Laboratory, Institute of Sport Science, Centre for Cognitive Science, Technische Universität DarmstadtDarmstadt, Germany.

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http://dx.doi.org/10.3389/fnbot.2017.00044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591611PMC
September 2017

Heterologous Production and Yield Improvement of Epothilones in Burkholderiales Strain DSM 7029.

ACS Chem Biol 2017 07 18;12(7):1805-1812. Epub 2017 May 18.

Shandong University-Helmholtz Institute of Biotechnology, State Key Laboratory of Microbial Technology, School of Life Science, Shandong University , Qingdao 266235, China.

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http://pubs.acs.org/doi/10.1021/acschembio.7b00097
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http://dx.doi.org/10.1021/acschembio.7b00097DOI Listing
July 2017

Multiplex gene regulation by CRISPR-ddCpf1.

Cell Discov 2017 6;3:17018. Epub 2017 Jun 6.

Key Laboratory of Synthetic Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.

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http://www.nature.com/articles/celldisc201718
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http://dx.doi.org/10.1038/celldisc.2017.18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460296PMC
June 2017

The effect of interface anisotropy on demagnetization progress in perpendicularly oriented hard/soft exchange-coupled multilayers.

Sci Rep 2017 06 27;7(1):4286. Epub 2017 Jun 27.

Inner Mongolia Key Laboratory for Utilization of Bayan Obo Multi-Metallic Resources; Elected State Key Laboratory; Department of Applied Physics, College of Science, Inner Mongolia University of Science and Technology, Baotou, 014010, China.

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http://dx.doi.org/10.1038/s41598-017-03169-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487335PMC
June 2017

Lysine acetylation regulates the function of the global anaerobic transcription factor FnrL in Rhodobacter sphaeroides.

Mol Microbiol 2017 04 28;104(2):278-293. Epub 2017 Feb 28.

CAS-Key Laboratory of Synthetic Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, 200032, China.

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http://dx.doi.org/10.1111/mmi.13627DOI Listing
April 2017

Pattern of novel object exploration in cynomolgus monkey Macaca fascicularis.

J Med Primatol 2017 04 25;46(2):19-24. Epub 2017 Jan 25.

Department of Genetics and Center of Alcohol Studies, Rutgers University, Piscataway, NJ, USA.

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http://dx.doi.org/10.1111/jmp.12251DOI Listing
April 2017

RifZ (AMED_0655) Is a Pathway-Specific Regulator for Rifamycin Biosynthesis in Amycolatopsis mediterranei.

Appl Environ Microbiol 2017 04 31;83(8). Epub 2017 Mar 31.

State Key Laboratory of Genetic Engineering, Department of Microbiology and Microbial Engineering, School of Life Sciences, Fudan University, Shanghai, China

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http://dx.doi.org/10.1128/AEM.03201-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377510PMC
April 2017

Development of dual-fluorescence cell-based biosensors for detecting the influence of environmental factors on nanoparticle toxicity.

Chemosphere 2017 Mar 18;171:177-184. Epub 2016 Dec 18.

Key Laboratory of Ion Beam Bioengineering, Hefei Institutes of Physical Science, China Academy of Science, Hefei, Anhui, PR China; Key Laboratory of Environmental Toxicology and Pollution Control Technology of Anhui Province, Hefei, Anhui, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.chemosphere.2016.12.076DOI Listing
March 2017

[Enabling technologies in synthetic biology--DNA synthesis, assembly and editing].

Sheng Wu Gong Cheng Xue Bao 2017 Mar;33(3):343-360

Key Laboratory of Synthetic Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200032, China.

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http://dx.doi.org/10.13345/j.cjb.160413DOI Listing
March 2017

Chemotaxis without Conventional Two-Component System, Based on Cell Polarity and Aerobic Conditions in Helicity-Switching Swimming of .

Front Microbiol 2017 3;8:58. Epub 2017 Feb 3.

Department of Biology, Graduate School of Science, Osaka City UniversityOsaka, Japan; The OCU Advanced Research Institute for Natural Science and Technology, Osaka City UniversityOsaka, Japan.

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http://dx.doi.org/10.3389/fmicb.2017.00058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289999PMC
February 2017

Bxb1 integrase serves as a highly efficient DNA recombinase in rapid metabolite pathway assembly.

Acta Biochim Biophys Sin (Shanghai) 2017 Jan 17;49(1):44-50. Epub 2016 Nov 17.

Collaborative Innovation Center for Genetics and Development, State Key Laboratory of Genetic Engineering, Department of Microbiology, School of Life Sciences, Fudan University, Shanghai 200438, China

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http://dx.doi.org/10.1093/abbs/gmw115DOI Listing
January 2017

Cyclic AMP Inhibits the Activity and Promotes the Acetylation of Acetyl-CoA Synthetase through Competitive Binding to the ATP/AMP Pocket.

J Biol Chem 2017 01 14;292(4):1374-1384. Epub 2016 Dec 14.

the Key Laboratory of Synthetic Biology, Chinese Academy of Sciences Center for Excellence in Molecular Plant Sciences, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200032, China,

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http://www.jbc.org/lookup/doi/10.1074/jbc.M116.753640
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http://dx.doi.org/10.1074/jbc.M116.753640DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270480PMC
January 2017

Theophylline controllable RNAi-based genetic switches regulate expression of lncRNA TINCR and malignant phenotypes in bladder cancer cells.

Sci Rep 2016 09 2;6:30798. Epub 2016 Sep 2.

Key Laboratory of Medical Reprogramming Technology, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen 518039, Guangdong Province, People's Republic of China.

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http://dx.doi.org/10.1038/srep30798DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009373PMC
September 2016

Perfluorooctane sulfonate exposure causes gonadal developmental toxicity in Caenorhabditis elegans through ROS-induced DNA damage.

Chemosphere 2016 Jul 22;155:115-126. Epub 2016 Apr 22.

Key Laboratory of Ion Beam Bioengineering, Hefei Institutes of Physical Science, Chinese Academy of Sciences, P O Box 1138, Hefei, Anhui 230031, PR China; School of Nuclear Science and Technology, University of Science and Technology of China, Hefei, Anhui 230026, PR China; Key Laboratory of Environmental Toxicology and Pollution Control Technology of Anhui Province, Hefei, Anhui 230026, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.chemosphere.2016.04.046DOI Listing
July 2016

Investigating the environmental factors affecting the toxicity of silver nanoparticles in Escherichia coli with dual fluorescence analysis.

Chemosphere 2016 Jul 29;155:329-335. Epub 2016 Apr 29.

Key Laboratory of Ion Beam Bioengineering, Hefei Institutes of Physical Science, China Academy of Sciences, Hefei, Anhui, PR China; Key Laboratory of Environmental Toxicology and Pollution Control Technology of Anhui Province, Hefei, Anhui, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.chemosphere.2016.04.074DOI Listing
July 2016

A new biarticular actuator design facilitates control of leg function in BioBiped3.

Bioinspir Biomim 2016 07 1;11(4):046003. Epub 2016 Jul 1.

Lauflabor Locomotion Laboratory, Technische Universität Darmstadt, Germany. School of ECE, College of Engineering, University of Tehran, Iran.

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http://dx.doi.org/10.1088/1748-3190/11/4/046003DOI Listing
July 2016

Synergistic Effect of Ferulic Acid and Z-Ligustilide, Major Components of A. sinensis, on Regulating Cold-Sensing Protein TRPM8 and TPRA1 In Vitro.

Evid Based Complement Alternat Med 2016 20;2016:3160247. Epub 2016 Jun 20.

Department of Traditional Chinese Medicine, College of Medicine, Jinan University, Guangzhou 510630, China.

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http://dx.doi.org/10.1155/2016/3160247DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931054PMC
July 2016

Tetracycline-inducible shRNA targeting antisense long non-coding RNA HIF1A-AS2 represses the malignant phenotypes of bladder cancer.

Cancer Lett 2016 06 24;376(1):155-64. Epub 2016 Mar 24.

Key Laboratory of Medical Reprogramming Technology, Shenzhen Second People's Hospital, Clinical Institute of Anhui Medical University, The First Affiliated Hospital of Shenzhen University, Shenzhen 518039, Guangdong Province, China; Anhui Medical University, Hefei 230032, Anhui Province, China; Shantou University Medical College, Shantou 515041, Guangdong Province, China; Department of Urology, Peking University First Hospital, Institute of Urology, Peking University, National Urological Cancer Center, Beijing 100034, China. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2016.03.037DOI Listing
June 2016

Synthetic tetracycline-controllable shRNA targeting long non-coding RNA HOXD-AS1 inhibits the progression of bladder cancer.

J Exp Clin Cancer Res 2016 06 21;35(1):99. Epub 2016 Jun 21.

Key Laboratory of Medical Reprogramming Technology, Shenzhen Second People's Hospital, Clinical Institute of Shantou University Medical College, First Affiliated Hospital of Shenzhen University, Shenzhen, 518039, Guangdong Province, People's Republic of China.

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http://dx.doi.org/10.1186/s13046-016-0372-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915162PMC
June 2016

A Comprehensive Analysis of the Transcriptomes of Marssonina brunnea and Infected Poplar Leaves to Capture Vital Events in Host-Pathogen Interactions.

PLoS One 2015 29;10(7):e0134246. Epub 2015 Jul 29.

State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, People's Republic of China; Shanghai-MOST Key Laboratory of Health and Disease Genomics, Chinese National Human Genome Center at Shanghai, Shanghai, People's Republic of China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0134246PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519268PMC
May 2016

shRNA targeting long non-coding RNA CCAT2 controlled by tetracycline-inducible system inhibits progression of bladder cancer cells.

Oncotarget 2016 May;7(20):28989-97

Key Laboratory of Medical Reprogramming Technology, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University, Shenzhen, China.

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http://dx.doi.org/10.18632/oncotarget.8259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045372PMC
May 2016

Inhibiting cell migration and cell invasion by silencing the transcription factor ETS-1 in human bladder cancer.

Oncotarget 2016 May;7(18):25125-34

Key Laboratory of Medical Reprogramming Technology, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041893PMC
http://dx.doi.org/10.18632/oncotarget.7192DOI Listing
May 2016

Characterization of the Ca(2+) -responsive signaling pathway in regulating the expression and secretion of cellulases in Trichoderma reesei Rut-C30.

Mol Microbiol 2016 05 2;100(3):560-75. Epub 2016 Mar 2.

Key Laboratory of Synthetic Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, 200032, China.

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http://dx.doi.org/10.1111/mmi.13334DOI Listing
May 2016

Up-regulation of long non-coding RNA PANDAR is associated with poor prognosis and promotes tumorigenesis in bladder cancer.

J Exp Clin Cancer Res 2016 05 20;35(1):83. Epub 2016 May 20.

Key Laboratory of Medical Reprogramming Technology, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University Shenzhen, Shenzhen, China.

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http://dx.doi.org/10.1186/s13046-016-0354-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873988PMC
May 2016

Insight into Dominant Cellulolytic Bacteria from Two Biogas Digesters and Their Glycoside Hydrolase Genes.

PLoS One 2015 12;10(6):e0129921. Epub 2015 Jun 12.

CAS-Key Laboratory of Synthetic Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0129921PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466528PMC
March 2016

sp. nov., isolated from soil.

Int J Syst Evol Microbiol 2016 Mar 23;66(3):1224-1229. Epub 2015 Dec 23.

1​ Collaborative Innovation Center for Genetics and Development, State Key Laboratory of Genetic Engineering, Department of Microbiology, School of Life Sciences, Fudan University, Shanghai, 200438, PRChina.

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http://dx.doi.org/10.1099/ijsem.0.000861DOI Listing
March 2016

Increased expression of SUMO1P3 predicts poor prognosis and promotes tumor growth and metastasis in bladder cancer.

Oncotarget 2016 Mar;7(13):16038-48

Key Laboratory of Medical Reprogramming Technology, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, China.

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http://dx.doi.org/10.18632/oncotarget.6946DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941296PMC
March 2016

Whole genome sequencing revealed host adaptation-focused genomic plasticity of pathogenic Leptospira.

Sci Rep 2016 Feb 2;6:20020. Epub 2016 Feb 2.

Key Laboratory of the Ministry of Health for Research on Quality and Standardization of Biotech Products, National Institutes of Food and Drug Control, Beijing 100050, People's Republic of China.

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http://dx.doi.org/10.1038/srep20020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735792PMC
February 2016

Synthetic Bax-Anti Bcl2 combination module actuated by super artificial hTERT promoter selectively inhibits malignant phenotypes of bladder cancer.

J Exp Clin Cancer Res 2016 Jan 8;35. Epub 2016 Jan 8.

Key Laboratory of Medical Reprogramming Technology, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, China.

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http://dx.doi.org/10.1186/s13046-015-0279-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705585PMC
January 2016

Tetracycline-inducible shRNA targeting long non-coding RNA PVT1 inhibits cell growth and induces apoptosis in bladder cancer cells.

Oncotarget 2015 Dec;6(38):41194-203

Key Laboratory of Medical Reprogramming Technology, Shenzhen Second People's Hospital, Shenzhen 518039, Guangdong Province, People's Republic of China.

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http://dx.doi.org/10.18632/oncotarget.5880DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747399PMC
December 2015

Synthetic Tet-inducible artificial microRNAs targeting β-catenin or HIF-1α inhibit malignant phenotypes of bladder cancer cells T24 and 5637.

Sci Rep 2015 Nov 6;5:16177. Epub 2015 Nov 6.

Key Laboratory of Medical Reprogramming Technology, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University Shenzhen, China.

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http://www.nature.com/articles/srep16177
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635424PMC
November 2015

GlnR-Mediated Regulation of ectABCD Transcription Expands the Role of the GlnR Regulon to Osmotic Stress Management.

J Bacteriol 2015 Oct 13;197(19):3041-7. Epub 2015 Jul 13.

CAS Key Laboratory of Synthetic Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China Key Laboratory of Medical Reprogramming Technology, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University, Shenzhen, China

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http://dx.doi.org/10.1128/JB.00185-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560291PMC
October 2015

Draft Genome Sequence of the Streptothricin-Producing Strain Streptomyces sp. fd2-tb.

Genome Announc 2015 Oct 29;3(5). Epub 2015 Oct 29.

Collaborative Innovation Center for Genetics and Development, State Key Laboratory of Genetic Engineering, Department of Microbiology, School of Life Sciences, Fudan University, Shanghai, China

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http://dx.doi.org/10.1128/genomeA.01277-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626613PMC
October 2015

Inducing cell growth arrest and apoptosis by silencing long non-coding RNA PCAT-1 in human bladder cancer.

Tumour Biol 2015 Sep 2;36(10):7685-9. Epub 2015 May 2.

Key Laboratory of Medical Reprogramming Technology, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, China.

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http://link.springer.com/10.1007/s13277-015-3490-3
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http://dx.doi.org/10.1007/s13277-015-3490-3DOI Listing
September 2015

Characterization of Panax ginseng UDP-Glycosyltransferases Catalyzing Protopanaxatriol and Biosyntheses of Bioactive Ginsenosides F1 and Rh1 in Metabolically Engineered Yeasts.

Mol Plant 2015 Sep 30;8(9):1412-24. Epub 2015 May 30.

CAS-Key Laboratory of Synthetic Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200032, China. Electronic address:

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http://dx.doi.org/10.1016/j.molp.2015.05.010DOI Listing
September 2015

Complete genome sequence of the glidobactin producing strain [Polyangium] brachysporum DSM 7029.

J Biotechnol 2015 Sep 30;210:83-4. Epub 2015 Jun 30.

Collaborative Innovation Center for Genetics and Development, State Key Laboratory of Genetic Engineering, Department of Microbiology, School of Life Sciences, Fudan University, Shanghai, China. Electronic address:

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http://dx.doi.org/10.1016/j.jbiotec.2015.06.417DOI Listing
September 2015

MEGA (Multiple Essential Genes Assembling) deletion and replacement method for genome reduction in Escherichia coli.

ACS Synth Biol 2015 Jun 17;4(6):700-6. Epub 2014 Dec 17.

Key Laboratory of Synthetic Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200032, China.

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http://dx.doi.org/10.1021/sb500324pDOI Listing
June 2015

Genome-wide analysis of homeobox genes from Mesobuthus martensii reveals Hox gene duplication in scorpions.

Insect Biochem Mol Biol 2015 Jun 21;61:25-33. Epub 2015 Apr 21.

College of Life Sciences, Wuhan University, Wuhan, China. Electronic address:

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http://dx.doi.org/10.1016/j.ibmb.2015.04.002DOI Listing
June 2015

NGSmirPlant: comprehensive characterization of the small RNA transcriptomes of plants.

Protein Cell 2015 Jun;6(6):397-402

Department of Microbiology and Microbial Engineering, School of Life Sciences, Fudan University, Shanghai, 200433, China.

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http://dx.doi.org/10.1007/s13238-015-0159-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444805PMC
June 2015

Genome-Wide Association Studies of HIV-1 Host Control in Ethnically Diverse Chinese Populations.

Sci Rep 2015 Jun 3;5:10879. Epub 2015 Jun 3.

The Key Laboratory of Stem Cell Biology, Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, and Shanghai Jiao Tong University School of Medicine, Shanghai 200031, People's Republic of China.

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http://dx.doi.org/10.1038/srep10879DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454153PMC
June 2015

Production of bioactive ginsenosides Rh2 and Rg3 by metabolically engineered yeasts.

Metab Eng 2015 May 11;29:97-105. Epub 2015 Mar 11.

CAS-Key Laboratory of Synthetic Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 300 Fenglin Road, Shanghai 200032, China. Electronic address:

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http://dx.doi.org/10.1016/j.ymben.2015.03.003DOI Listing
May 2015

Proapoptotic activities of protein disulfide isomerase (PDI) and PDIA3 protein, a role of the Bcl-2 protein Bak.

J Biol Chem 2015 Apr 19;290(14):8949-63. Epub 2015 Feb 19.

From the Molecular Targets Program, Departments of Medicine, Pharmacology, and Toxicology, University of Louisville, Louisville, Kentucky 40202 and

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http://www.jbc.org/lookup/doi/10.1074/jbc.M114.619353
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http://dx.doi.org/10.1074/jbc.M114.619353DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423685PMC
April 2015

Combined analysis with copy number variation identifies risk loci in lung cancer.

Biomed Res Int 2014 1;2014:469103. Epub 2014 Jul 1.

Institute of Health Sciences, Shanghai Jiao Tong University School of Medicine (SJTUSM) and Shanghai Institutes for Biological Sciences (SIBS), Chinese Academy of Sciences (CAS), Shanghai 200025, China ; State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University, 197 Ruijin Road II, Shanghai 200025, China.

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http://dx.doi.org/10.1155/2014/469103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100386PMC
March 2015

Differential behavior patterns in cynomolgus monkey Macaca fascicularis in home cage in response to human gaze.

J Med Primatol 2015 Feb 2;44(1):1-11. Epub 2014 Dec 2.

Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China; State Key Laboratory of Genetic Engineering, Department of Microbiology, School of Life Sciences and Institute of Biomedical Sciences, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1111/jmp.12154DOI Listing
February 2015

Comparing Mycobacterium tuberculosis genomes using genome topology networks.

BMC Genomics 2015 Feb 14;16:85. Epub 2015 Feb 14.

State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, 200433, People's Republic of China.

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http://dx.doi.org/10.1186/s12864-015-1259-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342819PMC
February 2015

Identification of three extra-chromosomal replicons in Leptospira pathogenic strain and development of new shuttle vectors.

BMC Genomics 2015 Feb 15;16:90. Epub 2015 Feb 15.

Department of Microbiology and Immunology, Institutes of Medical Science, Shanghai Jiao Tong University School of Medicine, 280 South Chongqing Road, Shanghai, 200025, China.

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http://www.biomedcentral.com/1471-2164/16/90
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http://dx.doi.org/10.1186/s12864-015-1321-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338851PMC
February 2015

Complete genome sequence of Lysinibacillus varians GY32, a bacterium with filament-to-rod cell cycle.

FEMS Microbiol Lett 2015 Jan 4;362(1):1-3. Epub 2014 Dec 4.

Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application, Guangdong Institute of Microbiology, 100 Xianlie Road, Yuexiu District, Guangzhou 510070, Guangdong, China State Key Laboratory of Applied Microbiology Southern China, 100 Xianlie Road, Yuexiu District, Guangzhou 510070, Guangdong, China

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http://dx.doi.org/10.1093/femsle/fnu010DOI Listing
January 2015

Chronic alcohol consumption from adolescence to adulthood in mice--hypothalamic gene expression changes in insulin-signaling pathway.

Alcohol 2014 Sep 5;48(6):571-8. Epub 2014 Jul 5.

Department of Genetics & Center of Alcohol Studies, Rutgers University, 607 Allison Road, Piscataway, NJ 08854, USA. Electronic address:

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http://dx.doi.org/10.1016/j.alcohol.2014.07.001DOI Listing
September 2014

Exome sequencing identifies frequent mutation of MLL2 in non-small cell lung carcinoma from Chinese patients.

Sci Rep 2014 Aug 12;4:6036. Epub 2014 Aug 12.

State Key Laboratory of Medical Genomics, Institute of Health Sciences, Shanghai Jiao Tong University School of Medicine and Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200025, People's Republic of China.

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http://dx.doi.org/10.1038/srep06036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381403PMC
August 2014

Re-characterization of an extrachromosomal circular plasmid in the pathogenic Leptospira interrogans serovar Lai strain 56601.

Acta Biochim Biophys Sin (Shanghai) 2014 Jul 29;46(7):605-11. Epub 2014 May 29.

Department of Microbiology and Immunology, Institute of Medical Science, Shanghai Jiao Tong University School of Medicine, 280 South Chongqing Road, Shanghai 200025, China

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http://dx.doi.org/10.1093/abbs/gmu033DOI Listing
July 2014

Production of bioactive ginsenoside compound K in metabolically engineered yeast.

Cell Res 2014 Jun 7;24(6):770-3. Epub 2014 Mar 7.

CAS-Key Laboratory of Synthetic Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200032, China.

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http://www.nature.com/articles/cr201428
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http://dx.doi.org/10.1038/cr.2014.28DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042165PMC
June 2014

Improvement of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry for identification of clinically important Candida species.

Clin Lab 2014 ;60(1):37-46

Tianjin Key Laboratory for Biomarkers of Occupational and Environmental Hazard, Logistics University of Chinese People's Armed Police Forces, Tianjin, China.

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March 2014