Guoping Feng

Guoping Feng

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Tmem119-EGFP and Tmem119-CreERT2 Transgenic Mice for Labeling and Manipulating Microglia.

eNeuro 2019 Jul/Aug;6(4). Epub 2019 Aug 26.

McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139

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http://dx.doi.org/10.1523/ENEURO.0448-18.2019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712208PMC
March 2020

Dysfunction of cortical GABAergic neurons leads to sensory hyper-reactivity in a Shank3 mouse model of ASD.

Nat Neurosci 2020 Mar 2. Epub 2020 Mar 2.

McGovern Institute for Brain Research, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA.

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http://dx.doi.org/10.1038/s41593-020-0598-6DOI Listing
March 2020

Differential excitatory vs inhibitory SCN expression at single cell level regulates brain sodium channel function in neurodevelopmental disorders.

Eur J Paediatr Neurol 2020 Jan 28;24:129-133. Epub 2019 Dec 28.

Cologne Center for Genomics, University of Cologne, University Hospital Cologne, Cologne, Germany; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Cambridge, MA, USA; Epilepsy Center, Neurological Institute, Cleveland Clinic, Cleveland, OH, USA; Genomic Medicine Institute, Lerner Research Institute Cleveland Clinic, Cleveland, OH, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ejpn.2019.12.019DOI Listing
January 2020

Combinatorial Targeting of Distributed Forebrain Networks Reverses Noise Hypersensitivity in a Model of Autism Spectrum Disorder.

Neuron 2019 11 21;104(3):488-500.e11. Epub 2019 Oct 21.

McGovern Institute for Brain Research and the Department of Brain and Cognitive Science, Massachusetts Institute of Technology, Cambridge, MA, USA; The Stanley Center for Psychiatric Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2019.09.040DOI Listing
November 2019

A VTA GABAergic Neural Circuit Mediates Visually Evoked Innate Defensive Responses.

Neuron 2019 08 12;103(3):473-488.e6. Epub 2019 Jun 12.

Shenzhen Key Lab of Neuropsychiatric Modulation and Collaborative Innovation Center for Brain Science, Guangdong Provincial Key Laboratory of Brain Connectome and Behavior, CAS Center for Excellence in Brain Science and Intelligence Technology, Brain Cognition and Brain Disease Institute (BCBDI), Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions, Shenzhen 518055, China; University of the Chinese Academy of Sciences, Beijing 100049, China. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2019.05.027DOI Listing
August 2019

Anterior cingulate cortex dysfunction underlies social deficits in Shank3 mutant mice.

Nat Neurosci 2019 08 22;22(8):1223-1234. Epub 2019 Jul 22.

Department of Neurobiology, School of Basic Medicine, Fourth Military Medical University, Xi'an, China.

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http://dx.doi.org/10.1038/s41593-019-0445-9DOI Listing
August 2019

Targeting Peripheral Somatosensory Neurons to Improve Tactile-Related Phenotypes in ASD Models.

Cell 2019 Aug;178(4):867-886.e24

Department of Neurobiology, Harvard Medical School, 220 Longwood Avenue, Boston, MA 02115, USA; Howard Hughes Medical Institute, Harvard Medical School, 220 Longwood Avenue, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.07.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704376PMC
August 2019

Two eARCHT3.0 Lines for Optogenetic Silencing of Dopaminergic and Serotonergic Neurons.

Front Neural Circuits 2019 1;13. Epub 2019 Feb 1.

McGovern Institute for Brain Research, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, United States.

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http://dx.doi.org/10.3389/fncir.2019.00004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367884PMC
July 2019

SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse.

Neuron 2019 07 3;103(2):217-234.e4. Epub 2019 Jun 3.

Department of Functional Genomics, CNCR, VU University and UMC Amsterdam, 1081 HV Amsterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2019.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764089PMC
July 2019

Lateral orbitofrontal dysfunction in the Sapap3 knockout mouse model of obsessive–compulsive disorder

J Psychiatry Neurosci 2019 03;44(2):120-131

From the Department of Neurobiology, Beijing Institute for Brain Disorders, Beijing Centre of Neural Regeneration and Repair, Key Laboratory for Neurodegenerative Diseases of the Ministry of Education, Capital Medical University, Beijing, China (Lei, Lai, Sun, Xu); the McGovern Institute for Brain Research, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts (Feng); and the Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts (Feng).

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http://dx.doi.org/10.1503/jpn.180032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397042PMC
March 2019

Deep convolutional network for animal sound classification and source attribution using dual audio recordings.

J Acoust Soc Am 2019 02;145(2):654

McGovern Institute for Brain Research, Massachusetts Institute of Technology, 43 Vassar Street, Cambridge, Massachusetts 02139, USA.

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http://dx.doi.org/10.1121/1.5087827DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6786887PMC
February 2019

Micro- and Nanotopography Sensitive Bacterial Attachment Mechanisms: A Review.

Front Microbiol 2019 21;10:191. Epub 2019 Feb 21.

Department of Food Science, Cornell University, Ithaca, NY, United States.

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http://dx.doi.org/10.3389/fmicb.2019.00191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393346PMC
February 2019

Differential Effects of Deep Brain Stimulation of the Internal Capsule and the Striatum on Excessive Grooming in Sapap3 Mutant Mice.

Biol Psychiatry 2018 12 23;84(12):917-925. Epub 2018 May 23.

Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences, Amsterdam, the Netherlands; Department of Psychiatry, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1016/j.biopsych.2018.05.011DOI Listing
December 2018

Functional Topography and Development of Inhibitory Reticulothalamic Barreloid Projections.

Front Neuroanat 2018 31;12:87. Epub 2018 Oct 31.

Department of Comparative Biomedical Sciences, Louisiana State University, School of Veterinary Medicine, Baton Rouge, LA, United States.

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https://www.frontiersin.org/article/10.3389/fnana.2018.00087
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http://dx.doi.org/10.3389/fnana.2018.00087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220084PMC
October 2018

Dichotomous parvalbumin interneuron populations in dorsolateral and dorsomedial striatum.

J Physiol 2018 08 9;596(16):3695-3707. Epub 2018 Jun 9.

McGovern Institute for Brain Research, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA.

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http://dx.doi.org/10.1113/JP275936DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092282PMC
August 2018

Thalamic Reticular Dysfunction as a Circuit Endophenotype in Neurodevelopmental Disorders.

Neuron 2018 04;98(2):282-295

McGovern Institute for Brain Research, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2018.03.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886707PMC
April 2018

Gamma Oscillation Dysfunction in mPFC Leads to Social Deficits in Neuroligin 3 R451C Knockin Mice.

Neuron 2018 03 1;97(6):1253-1260.e7. Epub 2018 Mar 1.

Department of Neurobiology, Key Laboratory of Medical Neurobiology of the Ministry of Health of China, Collaborative Innovation Center for Brain Science, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2018.02.001DOI Listing
March 2018

Windows of opportunity: timing in neurodevelopmental disorders.

Curr Opin Neurobiol 2018 02 7;48:59-63. Epub 2017 Nov 7.

McGovern Institute for Brain Research, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. Electronic address:

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http://dx.doi.org/10.1016/j.conb.2017.10.014DOI Listing
February 2018

Decreased Anxiety-Related Behaviour but Apparently Unperturbed NUMB Function in Ligand of NUMB Protein-X (LNX) 1/2 Double Knockout Mice.

Mol Neurobiol 2017 Dec 26;54(10):8090-8109. Epub 2016 Nov 26.

School of Biochemistry and Cell Biology, University College Cork, Cork, Ireland.

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http://dx.doi.org/10.1007/s12035-016-0261-0DOI Listing
December 2017

Alpha2delta-1 in SF1 Neurons of the Ventromedial Hypothalamus Is an Essential Regulator of Glucose and Lipid Homeostasis.

Cell Rep 2017 Dec;21(10):2737-2747

Department of Neuroscience, Tufts University School of Medicine, Boston, MA 02111, USA; Graduate Program in Neuroscience, Sackler School of Graduate Biomedical Sciences, Tufts University School of Medicine, Boston, MA 02111, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247173168
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http://dx.doi.org/10.1016/j.celrep.2017.11.048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730076PMC
December 2017

Synaptic Targeting and Function of SAPAPs Mediated by Phosphorylation-Dependent Binding to PSD-95 MAGUKs.

Cell Rep 2017 12;21(13):3781-3793

Division of Life Science, State Key Laboratory of Molecular Neuroscience, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China; Center of Systems Biology and Human Health, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.11.107DOI Listing
December 2017

Animal models for neuropsychiatric disorders: prospects for circuit intervention.

Curr Opin Neurobiol 2017 08 15;45:59-65. Epub 2017 Apr 15.

McGovern Institute for Brain Research, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09594388163027
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http://dx.doi.org/10.1016/j.conb.2017.03.010DOI Listing
August 2017

Impact of Mannanase-Producing Bacillus spp. on the Accuracy of the 3M Petrifilm Aerobic Count Method.

J Food Prot 2017 07;80(7):1117-1122

Olam Spices and Vegetable Ingredients, Innovation and Quality, 205 East River Park Place, Suite 310, Fresno, California 93720, USA.

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http://dx.doi.org/10.4315/0362-028X.JFP-16-473DOI Listing
July 2017

Chd8 Mutation Leads to Autistic-like Behaviors and Impaired Striatal Circuits.

Cell Rep 2017 04;19(2):335-350

Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Department of Brain and Cognitive Sciences, McGovern Institute for Brain Research, Cambridge, MA 02139, USA; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.03.052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455342PMC
April 2017

SHANK proteins: roles at the synapse and in autism spectrum disorder.

Nat Rev Neurosci 2017 03 9;18(3):147-157. Epub 2017 Feb 9.

McGovern Institute for Brain Research, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts 02139, USA.

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http://dx.doi.org/10.1038/nrn.2016.183DOI Listing
March 2017

Direct modulation of GFAP-expressing glia in the arcuate nucleus bi-directionally regulates feeding.

Elife 2016 10 18;5. Epub 2016 Oct 18.

Laboratory of Metabolic Medicine, Singapore Bioimaging Consortium, A*STAR, Singapore, Singapore.

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http://dx.doi.org/10.7554/eLife.18716DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068968PMC
October 2016

Opportunities and challenges in modeling human brain disorders in transgenic primates.

Nat Neurosci 2016 08;19(9):1123-30

McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.

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http://dx.doi.org/10.1038/nn.4362DOI Listing
August 2016

Central Mechanisms Mediating Thrombospondin-4-induced Pain States.

J Biol Chem 2016 Jun 19;291(25):13335-48. Epub 2016 Apr 19.

From the Department of Pharmacology and Department of Anesthesiology and Perioperative Care, University of California, Irvine, California 92697, Reeve-Irvine Research Center, University of California, Irvine, School of Medicine, Irvine, California 92697,

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http://www.jbc.org/content/early/2016/04/19/jbc.M116.723478.
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http://www.jbc.org/lookup/doi/10.1074/jbc.M116.723478
Publisher Site
http://dx.doi.org/10.1074/jbc.M116.723478DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933243PMC
June 2016

Efficient production of cynomolgus monkeys with a toolbox of enhanced assisted reproductive technologies.

Sci Rep 2016 05 13;6:25888. Epub 2016 May 13.

College of Veterinary Medicine, Guangdong Provincial Key Laboratory of Prevention and Control for Severe Clinical Animal Diseases, South China Agricultural University, Guangzhou 510642, P. R. China.

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http://dx.doi.org/10.1038/srep25888DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865753PMC
May 2016

Optogenetic Visualization of Presynaptic Tonic Inhibition of Cerebellar Parallel Fibers.

J Neurosci 2016 05;36(21):5709-23

Center for Functional Connectomics, Korea Institute of Science and Technology, Seoul 136-791, Republic of Korea, Lee Kong Chian School of Medicine, Nanyang Technological University, Research Techno Plaza, Singapore 637553 Singapore, Institute of Molecular and Cell Biology, Singapore 138673, Singapore, and MBL, Woods Hole, Massachusetts 02543

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http://dx.doi.org/10.1523/JNEUROSCI.4366-15.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879193PMC
May 2016

Thalamic reticular impairment underlies attention deficit in Ptchd1(Y/-) mice.

Nature 2016 Apr 23;532(7597):58-63. Epub 2016 Mar 23.

Neuroscience Institute, New York University Langone Medical Center, New York, New York 10016, USA.

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http://dx.doi.org/10.1038/nature17427DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875756PMC
April 2016

Neurobiology of social behavior abnormalities in autism and Williams syndrome.

Nat Neurosci 2016 Apr;19(6):647-655

McGovern Institute for Brain Research, MIT, Cambridge, Massachusetts, USA.

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http://dx.doi.org/10.1038/nn.4276DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896837PMC
April 2016

Optogenetic dissection of ictal propagation in the hippocampal-entorhinal cortex structures.

Nat Commun 2016 Mar 21;7:10962. Epub 2016 Mar 21.

Shenzhen Key Lab of Neuropsychiatric Modulation and Collaborative Innovation Center for Brain Science, CAS Center for Excellence in Brain Science and Intelligence Technology, the Brain Cognition and Brain Disease Institute (BCBDI) for Collaboration Research of SIAT at CAS and the McGovern Institute at MIT, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.

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http://dx.doi.org/10.1038/ncomms10962DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802168PMC
March 2016

Adult restoration of Shank3 expression rescues selective autistic-like phenotypes.

Nature 2016 Feb 17;530(7591):481-4. Epub 2016 Feb 17.

McGovern Institute for Brain Research, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.

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http://dx.doi.org/10.1038/nature16971DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898763PMC
February 2016

Impaired Dendritic Development and Memory in Sorbs2 Knock-Out Mice.

J Neurosci 2016 Feb;36(7):2247-60

McGovern Institute for Brain Research, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, Key Laboratory of Brain Functional Genomics (Ministry of Education and Science and Technology Commission of Shanghai Municipality), Institute of Cognitive Neuroscience, School of Psychology and Cognitive Science, East China Normal University, Shanghai 200062, China, Stanley Center for Psychiatric Research, Broad Institute of Massachusetts Institute of Technology, and Harvard, Cambridge, Massachusetts 02142,

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http://dx.doi.org/10.1523/JNEUROSCI.2528-15.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756157PMC
February 2016

Learning From Animal Models of Obsessive-Compulsive Disorder.

Biol Psychiatry 2016 Jan 4;79(1):7-16. Epub 2015 May 4.

McGovern Institute for Brain Research, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts; Stanley Center for Psychiatric Research, Eli and Edythe L. Broad Institute of MIT and Harvard, Cambridge, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2015.04.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633402PMC
January 2016

Mice with Shank3 Mutations Associated with ASD and Schizophrenia Display Both Shared and Distinct Defects.

Neuron 2016 Jan 10;89(1):147-62. Epub 2015 Dec 10.

McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S08966273150102
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http://dx.doi.org/10.1016/j.neuron.2015.11.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754122PMC
January 2016

Modeling psychiatric disorders for developing effective treatments.

Nat Med 2015 Sep;21(9):979-88

McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.

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http://search.proquest.com/openview/dc526050b90db3b22fd143e4
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http://www.nature.com/doifinder/10.1038/nm.3935
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http://dx.doi.org/10.1038/nm.3935DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886231PMC
September 2015

Brains, genes, and primates.

Neuron 2015 May;86(3):617-31

Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, MA 02142, USA; McGovern Institute for Brain Research at MIT, 43 Vassar Street, Cambridge, MA 02139, USA; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, 7 Massachusetts Avenue, Cambridge, MA 02139, USA; Department of Biological Engineering, Massachusetts Institute of Technology, 7 Massachusetts Avenue, Cambridge, MA 02139, USA; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, MA 02142, USA.

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http://dx.doi.org/10.1016/j.neuron.2015.03.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425847PMC
May 2015

Acute brain slice methods for adult and aging animals: application of targeted patch clamp analysis and optogenetics.

Methods Mol Biol 2014 ;1183:221-42

Human Cell Types Department, Allen Institute for Brain Science, 551 N 34th Street, Seattle, WA, 98103, USA,

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http://dx.doi.org/10.1007/978-1-4939-1096-0_14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219416PMC
February 2015

Striatal circuits, habits, and implications for obsessive-compulsive disorder.

Curr Opin Neurobiol 2015 Feb 19;30:59-65. Epub 2014 Sep 19.

McGovern Institute for Brain Research and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.conb.2014.08.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293232PMC
February 2015

The role of muscle microRNAs in repairing the neuromuscular junction.

PLoS One 2014 24;9(3):e93140. Epub 2014 Mar 24.

Department of Molecular and Cellular Biology and Center for Brain Science, Harvard University, Cambridge, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0093140PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963997PMC
November 2014

CRISPR-Cas9 knockin mice for genome editing and cancer modeling.

Cell 2014 Oct 25;159(2):440-55. Epub 2014 Sep 25.

Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2014.09.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265475PMC
October 2014

Bactericidal thurincin H causes unique morphological changes in Bacillus cereus F4552 without affecting membrane permeability.

FEMS Microbiol Lett 2014 Aug 30;357(1):69-76. Epub 2014 Jun 30.

Department of Food Science, Cornell University, Geneva, NY, USA.

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http://dx.doi.org/10.1111/1574-6968.12486DOI Listing
August 2014

Sensory integration in mouse insular cortex reflects GABA circuit maturation.

Neuron 2014 Aug 31;83(4):894-905. Epub 2014 Jul 31.

Department of Molecular and Cellular Biology, Center for Brain Science, Harvard University, 52 Oxford Street, Cambridge, MA 02138, USA; Department of Neurology, F.M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA; Canadian Institute for Advanced Research, 180 Dundas Street West, Toronto ON M5G 1Z8, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2014.06.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177076PMC
August 2014

Optogenetic mapping of cerebellar inhibitory circuitry reveals spatially biased coordination of interneurons via electrical synapses.

Cell Rep 2014 Jun 22;7(5):1601-1613. Epub 2014 May 22.

Lee Kong Chian School of Medicine, Nanyang Technological University, 50 Nanyang Drive, Research Techno Plaza, Singapore 637553, Singapore; Laboratory of Synaptic Circuitry, Program in Neuroscience and Behavioral Disorders, Duke-NUS Graduate Medical School, 8 College Road, Singapore 169857, Singapore; A(∗)STAR/Duke-NUS Neuroscience Research Partnership, 61 Biopolis Drive, Proteos, Singapore 138673, Singapore; Institute of Molecular and Cell Biology, 61 Biopolis Drive, Proteos, Singapore 138673, Singapore; Marine Biological Laboratory, Woods Hole, MA 02543, USA; Center for Functional Connectomics, Korea Institute of Science and Technology, 39-1 Hawolgokdong, Seongbukgu, Seoul 136-791, Republic of Korea; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117599, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.04.047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107211PMC
June 2014

Genome-scale neurogenetics: methodology and meaning.

Nat Neurosci 2014 Jun 27;17(6):756-63. Epub 2014 May 27.

1] Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA. [2] Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, Massachusetts, USA.

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http://dx.doi.org/10.1038/nn.3716DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912829PMC
June 2014

Circuit-selective striatal synaptic dysfunction in the Sapap3 knockout mouse model of obsessive-compulsive disorder.

Biol Psychiatry 2014 Apr 13;75(8):623-30. Epub 2013 Feb 13.

Department of Medicine, Division of Neurology, Durham, North Carolina; Department of Neurobiology, Durham, North Carolina. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2013.01.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3687030PMC
April 2014

Recombineering strategies for developing next generation BAC transgenic tools for optogenetics and beyond.

Front Behav Neurosci 2014 3;8:111. Epub 2014 Apr 3.

McGovern Institute for Brain Research and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology Cambridge, MA, USA.

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http://dx.doi.org/10.3389/fnbeh.2014.00111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982106PMC
April 2014

Selective activation of cholinergic basal forebrain neurons induces immediate sleep-wake transitions.

Curr Biol 2014 Mar 6;24(6):693-8. Epub 2014 Mar 6.

Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health of China, Key Laboratory of Neurobiology, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2014.02.011DOI Listing
March 2014

Flow of cortical activity underlying a tactile decision in mice.

Neuron 2014 Jan 19;81(1):179-94. Epub 2013 Dec 19.

Janelia Farm Research Campus, HHMI, Ashburn, VA 20147, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2013.10.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984938PMC
January 2014

Fast modulation of visual perception by basal forebrain cholinergic neurons.

Nat Neurosci 2013 Dec 27;16(12):1857-1863. Epub 2013 Oct 27.

Division of Neurobiology, Department of Molecular and Cell Biology, Helen Wills Neuroscience Institute, Howard Hughes Medical Institute, University of California, Berkeley, CA 94720.

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http://dx.doi.org/10.1038/nn.3552DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201942PMC
December 2013

Development of transgenic animals for optogenetic manipulation of mammalian nervous system function: progress and prospects for behavioral neuroscience.

Behav Brain Res 2013 Oct 6;255:3-18. Epub 2013 Mar 6.

McGovern Institute for Brain Research and Department of Brain & Cognitive Sciences, MIT, Cambridge, MA 02139, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01664328130011
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http://dx.doi.org/10.1016/j.bbr.2013.02.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030747PMC
October 2013

Optical inhibition of motor nerve and muscle activity in vivo.

Muscle Nerve 2013 Jun 30;47(6):916-21. Epub 2013 Apr 30.

Department of Mechanical Engineering, Stanford University, Stanford, California, USA.

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http://dx.doi.org/10.1002/mus.23696DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507203PMC
June 2013

Optogenetic stimulation of lateral orbitofronto-striatal pathway suppresses compulsive behaviors.

Science 2013 Jun;340(6137):1243-6

McGovern Institute for Brain Research and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1126/science.1232380DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876800PMC
June 2013

ChAT-ChR2-EYFP mice have enhanced motor endurance but show deficits in attention and several additional cognitive domains.

J Neurosci 2013 Jun;33(25):10427-38

Robarts Research Institute, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada N6A 5K8.

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http://dx.doi.org/10.1523/JNEUROSCI.0395-13.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6618591PMC
June 2013

Intersectional Cre driver lines generated using split-intein mediated split-Cre reconstitution.

Sci Rep 2012 6;2:497. Epub 2012 Jul 6.

Department of Cell Biology, Box 3709, Duke University Medical Center, Durham, NC, USA.

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http://dx.doi.org/10.1038/srep00497DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390602PMC
March 2013

Cortical control of affective networks.

J Neurosci 2013 Jan;33(3):1116-29

Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.0092-12.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711588PMC
January 2013

Functional consequences of mutations in postsynaptic scaffolding proteins and relevance to psychiatric disorders.

Annu Rev Neurosci 2012 20;35:49-71. Epub 2012 Apr 20.

McGovern Institute for Brain Research and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.

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http://www.annualreviews.org/doi/10.1146/annurev-neuro-06211
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http://dx.doi.org/10.1146/annurev-neuro-062111-150442DOI Listing
November 2012

Monoacylglycerol lipase is a therapeutic target for Alzheimer's disease.

Cell Rep 2012 Nov 1;2(5):1329-39. Epub 2012 Nov 1.

Neuroscience Center of Excellence, Louisiana State University Health New Orleans Sciences Center, New Orleans, LA 70112, USA.

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http://dx.doi.org/10.1016/j.celrep.2012.09.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513645PMC
November 2012

Cellular and synaptic network defects in autism.

Curr Opin Neurobiol 2012 Oct 20;22(5):866-72. Epub 2012 Mar 20.

McGovern Institute for Brain Research, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1016/j.conb.2012.02.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407823PMC
October 2012

Imaging neural activity using Thy1-GCaMP transgenic mice.

Neuron 2012 Oct 17;76(2):297-308. Epub 2012 Oct 17.

McGovern Institute for Brain Research, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1016/j.neuron.2012.07.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059513PMC
October 2012

Normal midbrain dopaminergic neuron development and function in miR-133b mutant mice.

J Neurosci 2012 Aug;32(32):10887-94

Department of Neurobiology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.1732-12.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3752074PMC
August 2012

[Application of facial tissue expander fibrous envelope for tension reduction].

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2012 Aug;26(8):939-42

Department of Medical Cosmetology, People's Hospital, Peking University, Beijing 100044, PR China.

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August 2012

A transcription activator-like effector toolbox for genome engineering.

Nat Protoc 2012 Jan 5;7(1):171-92. Epub 2012 Jan 5.

Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, USA.

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http://dx.doi.org/10.1038/nprot.2011.431DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684555PMC
January 2012

Sustained axon regeneration induced by co-deletion of PTEN and SOCS3.

Nature 2011 Nov 6;480(7377):372-5. Epub 2011 Nov 6.

F.M. Kirby Neurobiology Center, Children's Hospital, Department of Neurology, Harvard Medical School, 300 Longwood Avenue, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/nature10594DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240702PMC
November 2011

Unfolding neurodevelopmental disorders: found in translation.

Nat Med 2011 Nov 2;17(11):1352-3. Epub 2011 Nov 2.

McGovern Institute for Brain Research, Department of Brain and Cognitive Sciences, Stanley Center for Psychiatric Research, the Broad Institute, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.

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http://www.nature.com/articles/nm.2553
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November 2011

Sapap3 deletion causes mGluR5-dependent silencing of AMPAR synapses.

J Neurosci 2011 Nov;31(46):16685-91

Center for Translational Neuroscience, Division of Neurology, Duke University, Durham, North Carolina 27710, USA.

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http://www.jneurosci.org/cgi/doi/10.1523/JNEUROSCI.2533-11.2
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http://dx.doi.org/10.1523/JNEUROSCI.2533-11.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475185PMC
November 2011

SnapShot: Autism and the synapse.

Cell 2011 Oct;147(3):706, 706.e1

McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1016/j.cell.2011.10.015DOI Listing
October 2011

[Effect of in-utero surgical repair at different stages on mid-facial development of goats with cleft palate].

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2011 Sep;25(9):1099-102

Department of Aesthetic and Plastic Surgery, Peking University People's Hospital, Beijing 100044, PR China.

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September 2011