Guocheng Du

Guocheng Du

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Engineering of L-amino acid deaminases for the production of α-keto acids from L-amino acids.

Bioengineered 2019 12;10(1):43-51

a Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education , Jiangnan University , Wuxi , China.

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https://www.tandfonline.com/doi/full/10.1080/21655979.2019.1
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http://dx.doi.org/10.1080/21655979.2019.1595990DOI Listing
December 2019

Synthetic Biology Toolbox and Chassis Development in Bacillus subtilis.

Trends Biotechnol 2019 May 13;37(5):548-562. Epub 2018 Nov 13.

Key Laboratory of Industrial Biotechnology, Ministry of Education, Jiangnan University, Wuxi 214122, China; National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi 214122, China.

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http://dx.doi.org/10.1016/j.tibtech.2018.10.005DOI Listing
May 2019

Molecular engineering of chitinase from Bacillus sp. DAU101 for enzymatic production of chitooligosaccharides.

Enzyme Microb Technol 2019 May 30;124:54-62. Epub 2019 Jan 30.

Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi 214122, China; Key Laboratory of Industrial Biotechnology, Ministry of Education, Jiangnan University, Wuxi 214122, China. Electronic address:

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http://dx.doi.org/10.1016/j.enzmictec.2019.01.012DOI Listing
May 2019

Insight into subtilisin E-S7 cleavage pattern based on crystal structure and hydrolysates peptide analysis.

Biochem Biophys Res Commun 2019 May 23;512(3):623-628. Epub 2019 Mar 23.

School of Biotechnology, Jiangnan University, 1800 Lihu Road, Wuxi, 214122, Jiangsu, China; The Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, 1800 Lihu Road, Wuxi, 214122, Jiangsu, China. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2019.03.064DOI Listing
May 2019

Effective biodegradation of chicken feather waste by co-cultivation of keratinase producing strains.

Microb Cell Fact 2019 May 18;18(1):84. Epub 2019 May 18.

School of Biotechnology, Jiangnan University, 1800 Lihu Road, Wuxi, 214122, China.

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http://dx.doi.org/10.1186/s12934-019-1134-9DOI Listing
May 2019

Gene cloning and expression of the l-asparaginase from Bacillus cereus BDRD-ST26 in Bacillus subtilis WB600.

J Biosci Bioeng 2019 Apr 19;127(4):418-424. Epub 2018 Oct 19.

School of Biotechnology, Jiangnan University, Wuxi 214122, China; The Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi 214122, China.

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https://linkinghub.elsevier.com/retrieve/pii/S13891723183042
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http://dx.doi.org/10.1016/j.jbiosc.2018.09.007DOI Listing
April 2019

[Advances in microbial enzymatic elimination of ethyl carbamate in Chinese rice wine].

Sheng Wu Gong Cheng Xue Bao 2019 Apr;35(4):567-576

The Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, Jiangsu, China.

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http://dx.doi.org/10.13345/j.cjb.180386DOI Listing
April 2019

[Development of a purification tag to produce thermostable fused protein].

Sheng Wu Gong Cheng Xue Bao 2019 Apr;35(4):626-635

School of Biotechnology, Jiangnan University, Wuxi 214122, Jiangsu, China.

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http://dx.doi.org/10.13345/j.cjb.180363DOI Listing
April 2019

Metabolic engineering of Escherichia coli BL21 (DE3) for de novo production of L-DOPA from D-glucose.

Microb Cell Fact 2019 Apr 25;18(1):74. Epub 2019 Apr 25.

National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, 1800 Lihu Road, Wuxi, 214122, Jiangsu, China.

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https://microbialcellfactories.biomedcentral.com/articles/10
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http://dx.doi.org/10.1186/s12934-019-1122-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482505PMC
April 2019

Microbial production of sialic acid and sialylated human milk oligosaccharides: Advances and perspectives.

Biotechnol Adv 2019 Apr 24. Epub 2019 Apr 24.

Key Laboratory of Industrial Biotechnology, Ministry of Education, Jiangnan University, Wuxi 214122, China; National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi 214122, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S07349750193007
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http://dx.doi.org/10.1016/j.biotechadv.2019.04.011DOI Listing
April 2019

Combinatorial Fine-Tuning of GNA1 and GlmS Expression by 5'-Terminus Fusion Engineering Leads to Overproduction of N-Acetylglucosamine in Bacillus subtilis.

Biotechnol J 2019 Mar 4;14(3):e1800264. Epub 2018 Sep 4.

Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, No. 1800 Lihu Avenue, 214122 Wuxi, China.

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http://dx.doi.org/10.1002/biot.201800264DOI Listing
March 2019

Food-grade expression of an iron-containing acid urease in Bacillus subtilis.

J Biotechnol 2019 Mar 28;293:66-71. Epub 2019 Jan 28.

The Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, 214122, China; Synergetic Innovation Center of Food Safety and Nutrition, Jiangnan University, Wuxi, Jiangsu, 214122, China. Electronic address:

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http://dx.doi.org/10.1016/j.jbiotec.2019.01.012DOI Listing
March 2019

Pathway Engineering of Bacillus subtilis for Enhanced N-Acetylneuraminic Acid Production via Whole-Cell Biocatalysis.

Biotechnol J 2019 Mar 29:e1800682. Epub 2019 Mar 29.

Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, 214122, Wuxi, China.

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http://dx.doi.org/10.1002/biot.201800682DOI Listing
March 2019

Coupling feedback genetic circuits with growth phenotype for dynamic population control and intelligent bioproduction.

Metab Eng 2019 Mar 30;54:109-116. Epub 2019 Mar 30.

Department of Chemical, Biochemical and Environmental Engineering, University of Maryland Baltimore County, Baltimore, MD, 21250, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ymben.2019.03.009DOI Listing
March 2019

Metabolic Engineering of Saccharomyces cerevisiae to Improve Glucan Biosynthesis.

J Microbiol Biotechnol 2019 Mar 28. Epub 2019 Mar 28.

The Key Laboratory of Carbohydrate Chemistry and Biotechnology, Jiangnan University, P.R.China.

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http://dx.doi.org/10.4014/jmb.1812.12049DOI Listing
March 2019

Combinatorial Evolution of DNA with RECODE.

Methods Mol Biol 2018 ;1772:205-212

The Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, China.

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http://dx.doi.org/10.1007/978-1-4939-7795-6_11DOI Listing
February 2019

DNA Assembly with the DATEL Method.

Methods Mol Biol 2018 ;1772:421-428

The Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, China.

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http://dx.doi.org/10.1007/978-1-4939-7795-6_24DOI Listing
February 2019

Piggery wastewater treatment by aerobic granular sludge: Granulation process and antibiotics and antibiotic-resistant bacteria removal and transport.

Bioresour Technol 2019 Feb 9;273:350-357. Epub 2018 Nov 9.

Jiangsu Key Laboratory of Anaerobic Biotechnology, School of Environment and Civil Engineering, Jiangnan University, Wuxi 214122, China; Jiangsu College of Water Treatment Technology and Material Collaborative Innovation Center, Suzhou 215009, China. Electronic address:

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http://dx.doi.org/10.1016/j.biortech.2018.11.023DOI Listing
February 2019

Engineering of multiple modular pathways for high-yield production of 5-aminolevulinic acid in Escherichia coli.

Bioresour Technol 2019 Feb 3;274:353-360. Epub 2018 Dec 3.

The Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, China; The Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi 214122, China. Electronic address:

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http://dx.doi.org/10.1016/j.biortech.2018.12.004DOI Listing
February 2019

Protein engineering to enhance keratinolytic protease activity and excretion in Escherichia coli and its scale-up fermentation for high extracellular yield.

Enzyme Microb Technol 2019 Feb 10;121:37-44. Epub 2018 Nov 10.

Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi 214122, China; School of Biotechnology, Jiangnan University, Wuxi 214122, China.

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http://dx.doi.org/10.1016/j.enzmictec.2018.11.003DOI Listing
February 2019

An efficient thermostabilization strategy based on self-assembling amphipathic peptides for fusion tags.

Enzyme Microb Technol 2019 Feb 17;121:68-77. Epub 2018 Nov 17.

National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi, 214122, China; School of Biotechnology, Jiangnan University, Wuxi, 214122, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01410229183050
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http://dx.doi.org/10.1016/j.enzmictec.2018.11.004DOI Listing
February 2019

Synthetic repetitive extragenic palindromic (REP) sequence as an efficient mRNA stabilizer for protein production and metabolic engineering in prokaryotic cells.

Biotechnol Bioeng 2019 Jan 27;116(1):5-18. Epub 2018 Oct 27.

Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi, China.

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http://doi.wiley.com/10.1002/bit.26841
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http://dx.doi.org/10.1002/bit.26841DOI Listing
January 2019

Synthetic redesign of central carbon and redox metabolism for high yield production of N-acetylglucosamine in Bacillus subtilis.

Metab Eng 2019 01 19;51:59-69. Epub 2018 Oct 19.

Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi 214122, China; Key Laboratory of Industrial Biotechnology, Ministry of Education, Jiangnan University, Wuxi 214122, China. Electronic address:

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http://dx.doi.org/10.1016/j.ymben.2018.10.002DOI Listing
January 2019

Reactivation and pilot-scale application of long-term storage denitrification biofilm based on flow cytometry.

Water Res 2019 01 30;148:368-377. Epub 2018 Oct 30.

Jiangsu Key Laboratory of Anaerobic Biotechnology, School of Environment and Civil Engineering, Jiangnan University, Wuxi, 214122, China; Jiangsu College of Water Treatment Technology and Material Collaborative Innovation Center, Suzhou, 215009, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00431354183087
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http://dx.doi.org/10.1016/j.watres.2018.10.072DOI Listing
January 2019

Construction of Synthetic Promoters by Assembling the Sigma Factor Binding -35 and -10 Boxes.

Biotechnol J 2019 Jan 7;14(1):e1800298. Epub 2018 Dec 7.

The Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, 214122, China.

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http://doi.wiley.com/10.1002/biot.201800298
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http://dx.doi.org/10.1002/biot.201800298DOI Listing
January 2019

Combinatorial pathway enzyme engineering and host engineering overcomes pyruvate overflow and enhances overproduction of N-acetylglucosamine in Bacillus subtilis.

Microb Cell Fact 2019 Jan 4;18(1). Epub 2019 Jan 4.

Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi, 214122, China.

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http://dx.doi.org/10.1186/s12934-018-1049-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318901PMC
January 2019

Combinatorial Fine-Tuning of Phospholipase D Expression by WB600 for the Production of Phosphatidylserine.

J Microbiol Biotechnol 2018 Dec;28(12):2046-2056

Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi 214122, P.R. China.

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http://dx.doi.org/10.4014/jmb.1806.06048DOI Listing
December 2018

A new sRNA-mediated posttranscriptional regulation system for Bacillus subtilis.

Biotechnol Bioeng 2018 12 1;115(12):2986-2995. Epub 2018 Oct 1.

The Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, China.

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http://doi.wiley.com/10.1002/bit.26833
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http://dx.doi.org/10.1002/bit.26833DOI Listing
December 2018

Improved acid-stress tolerance of Lactococcus lactis NZ9000 and Escherichia coli BL21 by overexpression of the anti-acid component recT.

J Ind Microbiol Biotechnol 2018 Dec 19;45(12):1091-1101. Epub 2018 Sep 19.

The Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, 1800 Lihu Road, Wuxi, 214122, Jiangsu, China.

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http://dx.doi.org/10.1007/s10295-018-2075-8DOI Listing
December 2018

Characterization of a Lactobacillus brevis strain with potential oral probiotic properties.

BMC Microbiol 2018 12 22;18(1):221. Epub 2018 Dec 22.

Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, 214122, China.

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http://dx.doi.org/10.1186/s12866-018-1369-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303927PMC
December 2018

Enhanced 2,5-Furandicarboxylic Acid (FDCA) Production in BF60 by Manipulation of the Key Genes in FDCA Biosynthesis Pathway.

J Microbiol Biotechnol 2018 Dec;28(12):1999-2008

Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, 214122 Wuxi, P.R. China.

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http://dx.doi.org/10.4014/jmb.1808.8057DOI Listing
December 2018

Advances and prospects of Bacillus subtilis cellular factories: From rational design to industrial applications.

Metab Eng 2018 11 21;50:109-121. Epub 2018 May 21.

Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi 214122, China; Key Laboratory of Industrial Biotechnology, Ministry of Education, Jiangnan University, Wuxi 214122, China. Electronic address:

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http://dx.doi.org/10.1016/j.ymben.2018.05.006DOI Listing
November 2018

Current challenges facing one-step production of l-ascorbic acid.

Biotechnol Adv 2018 11 19;36(7):1882-1899. Epub 2018 Jul 19.

School of Biotechnology and Key Laboratory of Industrial Biotechnology, Ministry of Education, Jiangnan University, 1800 Lihu Road, Wuxi, Jiangsu 214122, China; National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, 1800 Lihu Road, Wuxi, Jiangsu 214122, China. Electronic address:

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http://dx.doi.org/10.1016/j.biotechadv.2018.07.006DOI Listing
November 2018

Improving bioconversion of eugenol to coniferyl alcohol by in situ eliminating harmful HO.

Bioresour Technol 2018 Nov 21;267:578-583. Epub 2018 Jul 21.

Key Laboratory of Industrial Biotechnology, Ministry of Education and School of Biotechnology, Jiangnan University, 1800 Lihu Road, Wuxi, Jiangsu 214122, China; National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, 1800 Lihu Road, Wuxi, Jiangsu 214122, China; Jiangsu Provisional Research Center for Bioactive Product Processing Technology, Jiangnan University, 1800 Lihu Road, Wuxi, Jiangsu 214122, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09608524183103
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http://dx.doi.org/10.1016/j.biortech.2018.07.104DOI Listing
November 2018

Biocatalytic Production of Glucosamine from -Acetylglucosamine by Diacetylchitobiose Deacetylase.

J Microbiol Biotechnol 2018 Nov;28(11):1850-1858

Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi 214122, P.R. China.

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http://dx.doi.org/10.4014/jmb.1805.05061DOI Listing
November 2018

[Optimized expression of heparin sulfotransferases and their application in sulfation of animal derived heparin].

Sheng Wu Gong Cheng Xue Bao 2018 Nov;34(11):1784-1793

Key Laboratory of Industrial Biotechnology, Ministry of Education, Jiangnan University, Wuxi 214122, Jiangsu, China.

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http://dx.doi.org/10.13345/j.cjb.180277DOI Listing
November 2018

A multifunctional tag with the ability to benefit the expression, purification, thermostability and activity of recombinant proteins.

J Biotechnol 2018 Oct 4;283:1-10. Epub 2018 Jul 4.

National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi 214122, China; School of Biotechnology, Jiangnan University, Wuxi 214122, China. Electronic address:

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http://dx.doi.org/10.1016/j.jbiotec.2018.07.005DOI Listing
October 2018

Separation and purification of α-ketoglutarate and pyruvate from the fermentation broth of Yarrowia lipolytica.

Bioprocess Biosyst Eng 2018 Oct 11;41(10):1519-1527. Epub 2018 Jul 11.

Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, 1800 Lihu Road, Wuxi, 214122, Jiangsu, China.

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http://dx.doi.org/10.1007/s00449-018-1979-zDOI Listing
October 2018

Engineering a Glucosamine-6-phosphate Responsive glmS Ribozyme Switch Enables Dynamic Control of Metabolic Flux in Bacillus subtilis for Overproduction of N-Acetylglucosamine.

ACS Synth Biol 2018 Oct 19;7(10):2423-2435. Epub 2018 Sep 19.

Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education , Jiangnan University , Wuxi 214122 , China.

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http://dx.doi.org/10.1021/acssynbio.8b00196DOI Listing
October 2018

Combinatorial synthetic pathway fine-tuning and comparative transcriptomics for metabolic engineering of Raoultella ornithinolytica BF60 to efficiently synthesize 2,5-furandicarboxylic acid.

Biotechnol Bioeng 2018 09 22;115(9):2148-2155. Epub 2018 May 22.

Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi, China.

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http://dx.doi.org/10.1002/bit.26725DOI Listing
September 2018

Modular pathway engineering of key carbon-precursor supply-pathways for improved N-acetylneuraminic acid production in Bacillus subtilis.

Biotechnol Bioeng 2018 09 12;115(9):2217-2231. Epub 2018 Jul 12.

Key Laboratory of Industrial Biotechnology, Ministry of Education, Jiangnan University, Wuxi, China.

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http://dx.doi.org/10.1002/bit.26743DOI Listing
September 2018

Synergistic Rewiring of Carbon Metabolism and Redox Metabolism in Cytoplasm and Mitochondria of Aspergillus oryzae for Increased l-Malate Production.

ACS Synth Biol 2018 Sep 21;7(9):2139-2147. Epub 2018 Aug 21.

Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education , Jiangnan University , Wuxi 214122 , China.

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http://pubs.acs.org/doi/10.1021/acssynbio.8b00130
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http://dx.doi.org/10.1021/acssynbio.8b00130DOI Listing
September 2018

CRISPRi allows optimal temporal control of N-acetylglucosamine bioproduction by a dynamic coordination of glucose and xylose metabolism in Bacillus subtilis.

Metab Eng 2018 09 31;49:232-241. Epub 2018 Aug 31.

Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi 214122, China; Key Laboratory of Industrial Biotechnology, Ministry of Education, Jiangnan University, Wuxi 214122, China. Electronic address:

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http://dx.doi.org/10.1016/j.ymben.2018.08.012DOI Listing
September 2018

The Soluble and Particulate Form of Alginates Positively Regulate Immune Response.

Iran J Immunol 2018 Sep;15(3):228-238

School of Biochemical Engineering, Anhui Polytechnic University, Wuhu, Anhui, China.

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http://dx.doi.org/10.22034/IJI.2018.39392DOI Listing
September 2018

Bio-Based Strategies for Producing Glycosaminoglycans and Their Oligosaccharides.

Trends Biotechnol 2018 08 16;36(8):806-818. Epub 2018 Apr 16.

Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, 214122, China.

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http://dx.doi.org/10.1016/j.tibtech.2018.03.010DOI Listing
August 2018

Adaptive Evolution Relieves Nitrogen Catabolite Repression and Decreases Urea Accumulation in Cultures of the Chinese Rice Wine Yeast Strain Saccharomyces cerevisiae XZ-11.

J Agric Food Chem 2018 Aug 26;66(34):9061-9069. Epub 2018 Jun 26.

Key Laboratory of Industrial Biotechnology, Ministry of Education, and School of Biotechnology , Jiangnan University , 1800 Lihu Road , Wuxi , Jiangsu 214122 , China.

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http://dx.doi.org/10.1021/acs.jafc.8b01313DOI Listing
August 2018

Bioaugmentation with Mixed Hydrogen-Producing Acetogen Cultures Enhances Methane Production in Molasses Wastewater Treatment.

Archaea 2018 1;2018:4634898. Epub 2018 Aug 1.

Jiangsu Key Laboratory of Anaerobic Biotechnology, School of Environment and Civil Engineering, Jiangnan University, Wuxi 214122, China.

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https://www.hindawi.com/journals/archaea/2018/4634898/
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http://dx.doi.org/10.1155/2018/4634898DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093043PMC
August 2018

One step synthesis of unnatural β-arylalanines using mutant phenylalanine aminomutase from Taxus chinensis with high β-regioselectivity.

Enzyme Microb Technol 2018 Jul 21;114:22-28. Epub 2018 Mar 21.

Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, 214122, People's Republic of China.

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http://dx.doi.org/10.1016/j.enzmictec.2018.03.006DOI Listing
July 2018

[Enhancing thermal stability of glucose oxidase by fusing amphiphilic short peptide].

Sheng Wu Gong Cheng Xue Bao 2018 Jul;34(7):1106-1116

National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi 214122, Jiangsu, China.

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http://doi.cnki.net/Resolution/Handler?doi=10.13345/j.cjb.18
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http://dx.doi.org/10.13345/j.cjb.180019DOI Listing
July 2018

Regulation of Sensing, Transportation, and Catabolism of Nitrogen Sources in Saccharomyces cerevisiae.

Microbiol Mol Biol Rev 2018 06 7;82(1). Epub 2018 Feb 7.

Key Laboratory of Industrial Biotechnology, Ministry of Education and School of Biotechnology, Jiangnan University, Wuxi, Jiangsu, China

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http://dx.doi.org/10.1128/MMBR.00040-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813884PMC
June 2018

A microbial-enzymatic strategy for producing chondroitin sulfate glycosaminoglycans.

Biotechnol Bioeng 2018 06 25;115(6):1561-1570. Epub 2018 Mar 25.

The Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, China.

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http://dx.doi.org/10.1002/bit.26577DOI Listing
June 2018

Evolutionary engineering of industrial microorganisms-strategies and applications.

Appl Microbiol Biotechnol 2018 Jun 5;102(11):4615-4627. Epub 2018 Apr 5.

School of Biotechnology, Jiangnan University, 1800 Lihu Road, Wuxi, 214122, Jiangsu, China.

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http://dx.doi.org/10.1007/s00253-018-8937-1DOI Listing
June 2018

Transcriptional regulator XYR1 activates the expression of cellobiose synthase to promote the production of cellulase from glucose.

Biotechnol Lett 2018 Jun 21;40(6):973-979. Epub 2018 Apr 21.

School of Biotechnology, Jiangnan University, Wuxi, 214122, People's Republic of China.

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http://dx.doi.org/10.1007/s10529-018-2549-9DOI Listing
June 2018

Deep dewatering process of sludge by chemical conditioning and its potential influence on wastewater treatment plants.

Environ Sci Pollut Res Int 2018 Jun 15. Epub 2018 Jun 15.

Jiangsu Key Laboratory of Anaerobic Biotechnology, School of Environment and Civil Engineering, Jiangnan University, Wuxi, 214122, China.

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http://dx.doi.org/10.1007/s11356-018-2351-1DOI Listing
June 2018

Recent advances in enhanced enzyme activity, thermostability and secretion by N-glycosylation regulation in yeast.

Biotechnol Lett 2018 May 15;40(5):847-854. Epub 2018 Feb 15.

Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, 214122, People's Republic of China.

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http://dx.doi.org/10.1007/s10529-018-2526-3DOI Listing
May 2018

Accumulation of Citrulline by Microbial Arginine Metabolism during Alcoholic Fermentation of Soy Sauce.

J Agric Food Chem 2018 Mar 23;66(9):2108-2113. Epub 2018 Feb 23.

Guangdong Pearl River Bridge Biotechnology Co. Ltd., Zhongshan 528415 , China.

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http://dx.doi.org/10.1021/acs.jafc.7b06053DOI Listing
March 2018

Enhanced pyruvate production in Candida glabrata by carrier engineering.

Biotechnol Bioeng 2018 02 6;115(2):473-482. Epub 2017 Nov 6.

Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, Jiangsu, China.

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http://doi.wiley.com/10.1002/bit.26477
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http://dx.doi.org/10.1002/bit.26477DOI Listing
February 2018

Comparative genomics and transcriptomics analysis-guided metabolic engineering of Propionibacterium acidipropionici for improved propionic acid production.

Biotechnol Bioeng 2018 02 1;115(2):483-494. Epub 2017 Dec 1.

Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi, China.

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http://dx.doi.org/10.1002/bit.26478DOI Listing
February 2018

Metabolic engineering of carbon overflow metabolism of Bacillus subtilis for improved N-acetyl-glucosamine production.

Bioresour Technol 2018 Feb 26;250:642-649. Epub 2017 Oct 26.

Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi 214122, China; Key Laboratory of Industrial Biotechnology, Ministry of Education, Jiangnan University, Wuxi 214122, China.

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https://linkinghub.elsevier.com/retrieve/pii/S09608524173182
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http://dx.doi.org/10.1016/j.biortech.2017.10.007DOI Listing
February 2018

Improved production of 2,5-furandicarboxylic acid by overexpression of 5-hydroxymethylfurfural oxidase and 5-hydroxymethylfurfural/furfural oxidoreductase in Raoultella ornithinolytica BF60.

Bioresour Technol 2018 Jan 1;247:1184-1188. Epub 2017 Sep 1.

Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi 214122, China; Key Laboratory of Industrial Biotechnology, Ministry of Education, Jiangnan University, Wuxi 214122, China.

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http://dx.doi.org/10.1016/j.biortech.2017.08.166DOI Listing
January 2018

High-yield secretory production of stable, active trypsin through engineering of the N-terminal peptide and self-degradation sites in Pichia pastoris.

Bioresour Technol 2018 Jan 4;247:81-87. Epub 2017 Aug 4.

Key Laboratory of Industrial Biotechnology, Ministry of Education, Jiangnan University, 1800 Lihu Road, Wuxi, Jiangsu 214122, China; Synergetic Innovation Center of Food Safety and Nutrition, 1800 Lihu Road, Wuxi, Jiangsu 214122, China; The Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, China.

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https://linkinghub.elsevier.com/retrieve/pii/S09608524173131
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http://dx.doi.org/10.1016/j.biortech.2017.08.006DOI Listing
January 2018

Construction and Characterization of Broad-Spectrum Promoters for Synthetic Biology.

ACS Synth Biol 2018 01 1;7(1):287-291. Epub 2017 Nov 1.

The Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University , Wuxi 214122, China.

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http://dx.doi.org/10.1021/acssynbio.7b00258DOI Listing
January 2018

Antiangiogenic effects of recombinant human endostatin in lung cancers.

Mol Med Rep 2018 Jan 24;17(1):79-86. Epub 2017 Oct 24.

Tumor Department of TCM, Sichuan Cancer Hospital and Institute, Chengdu, Sichuan 610000, P.R. China.

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http://dx.doi.org/10.3892/mmr.2017.7859DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780156PMC
January 2018

Efficient expression of cyclodextrin glycosyltransferase from Geobacillus stearothermophilus in Escherichia coli by promoter engineering and downstream box evolution.

J Biotechnol 2018 Jan 13;266:77-83. Epub 2017 Dec 13.

Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi, 214122, China; Key Laboratory of Industrial Biotechnology, Ministry of Education, Jiangnan University, Wuxi, 214122, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01681656173176
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http://dx.doi.org/10.1016/j.jbiotec.2017.12.009DOI Listing
January 2018

Combinatorial promoter engineering of glucokinase and phosphoglucoisomerase for improved N-acetylglucosamine production in Bacillus subtilis.

Bioresour Technol 2017 Dec 9;245(Pt A):1093-1102. Epub 2017 Sep 9.

Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi 214122, China; Key Laboratory of Industrial Biotechnology, Ministry of Education, Jiangnan University, Wuxi 214122, China.

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http://dx.doi.org/10.1016/j.biortech.2017.09.063DOI Listing
December 2017

Spatial organization of silybin biosynthesis in milk thistle [Silybum marianum (L.) Gaertn].

Plant J 2017 Dec 11;92(6):995-1004. Epub 2017 Nov 11.

Key Laboratory of Industrial Biotechnology, Ministry of Education and School of Biotechnology, Jiangnan University, 1800 Lihu Road, Wuxi, Jiangsu, 214122, China.

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http://dx.doi.org/10.1111/tpj.13736DOI Listing
December 2017

Biological production of L-malate: recent advances and future prospects.

World J Microbiol Biotechnol 2017 Dec 6;34(1). Epub 2017 Dec 6.

Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi, 214122, China.

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http://dx.doi.org/10.1007/s11274-017-2349-8DOI Listing
December 2017

Keratinolytic protease: a green biocatalyst for leather industry.

Appl Microbiol Biotechnol 2017 Nov 18;101(21):7771-7779. Epub 2017 Sep 18.

School of Biotechnology, Jiangnan University, 1800 Lihu Road, Wuxi, 214122, China.

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http://dx.doi.org/10.1007/s00253-017-8484-1DOI Listing
November 2017

Metabolic engineering of Aspergillus oryzae for efficient production of l-malate directly from corn starch.

J Biotechnol 2017 Nov 28;262:40-46. Epub 2017 Sep 28.

Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi 214122, China; Key Laboratory of Industrial Biotechnology, Ministry of Education, Jiangnan University, Wuxi 214122, China. Electronic address:

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http://dx.doi.org/10.1016/j.jbiotec.2017.09.021DOI Listing
November 2017

Rewiring the Glucose Transportation and Central Metabolic Pathways for Overproduction of N-Acetylglucosamine in Bacillus subtilis.

Biotechnol J 2017 Oct 14;12(10). Epub 2017 Aug 14.

Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi, 214122, China.

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http://doi.wiley.com/10.1002/biot.201700020
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October 2017

Recent advances in production of 5-aminolevulinic acid using biological strategies.

World J Microbiol Biotechnol 2017 Oct 16;33(11):200. Epub 2017 Oct 16.

Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, 1800 Lihu Road, Wuxi, 214122, Jiangsu, China.

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http://link.springer.com/10.1007/s11274-017-2366-7
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October 2017

Engineering of an H O auto-scavenging in vivo cascade for pinoresinol production.

Biotechnol Bioeng 2017 09 12;114(9):2066-2074. Epub 2017 May 12.

Key Laboratory of Industrial Biotechnology, Ministry of Education and School of Biotechnology, Jiangnan University, 1800 Lihu Road, Wuxi, Jiangsu, 214122, China.

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http://dx.doi.org/10.1002/bit.26319DOI Listing
September 2017

Metabolic engineering of cofactor flavin adenine dinucleotide (FAD) synthesis and regeneration in Escherichia coli for production of α-keto acids.

Biotechnol Bioeng 2017 09 27;114(9):1928-1936. Epub 2017 Jun 27.

Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi, China, 214122.

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http://doi.wiley.com/10.1002/bit.26336
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http://dx.doi.org/10.1002/bit.26336DOI Listing
September 2017

Protein and metabolic engineering for the production of organic acids.

Bioresour Technol 2017 Sep 14;239:412-421. Epub 2017 Apr 14.

Key Laboratory of Industrial Biotechnology, Ministry of Education, Jiangnan University, Wuxi 214122, China.

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http://dx.doi.org/10.1016/j.biortech.2017.04.052DOI Listing
September 2017

A Bacillus paralicheniformis Iron-Containing Urease Reduces Urea Concentrations in Rice Wine.

Appl Environ Microbiol 2017 09 17;83(17). Epub 2017 Aug 17.

The Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, China, and Synergetic Innovation Center of Food Safety and Nutrition, Jiangnan University, Wuxi, China

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http://aem.asm.org/lookup/doi/10.1128/AEM.01258-17
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http://dx.doi.org/10.1128/AEM.01258-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561274PMC
September 2017

Tuning the transcription and translation of L-amino acid deaminase in Escherichia coli improves α-ketoisocaproate production from L-leucine.

PLoS One 2017 29;12(6):e0179229. Epub 2017 Jun 29.

Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0179229PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491005PMC
September 2017

5-Aminolevulinic acid production from inexpensive glucose by engineering the C4 pathway in Escherichia coli.

J Ind Microbiol Biotechnol 2017 08 5;44(8):1127-1135. Epub 2017 Apr 5.

The Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, 214122, People's Republic of China.

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http://dx.doi.org/10.1007/s10295-017-1940-1DOI Listing
August 2017

Self-induction system for cellulase production by cellobiose produced from glucose in Rhizopus stolonifer.

Sci Rep 2017 08 31;7(1):10161. Epub 2017 Aug 31.

School of Biotechnology, Jiangnan University, Wuxi, 214122, China.

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http://dx.doi.org/10.1038/s41598-017-10964-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579273PMC
August 2017

Rewiring the reductive tricarboxylic acid pathway and L-malate transport pathway of Aspergillus oryzae for overproduction of L-malate.

J Biotechnol 2017 Jul 12;253:1-9. Epub 2017 May 12.

Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi 214122, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01681656173024
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http://dx.doi.org/10.1016/j.jbiotec.2017.05.011DOI Listing
July 2017

Evaluation and application of constitutive promoters for cutinase production by Saccharomyces cerevisiae.

J Microbiol 2017 Jul 30;55(7):538-544. Epub 2017 Jun 30.

The Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, 214122, P. R. China.

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http://dx.doi.org/10.1007/s12275-017-6514-4DOI Listing
July 2017

[Engineering and characterization of new intrinsic transcriptional terminators in Bacillus subtilis 168].

Sheng Wu Gong Cheng Xue Bao 2017 Jul;33(7):1091-1100

The Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, Jiangsu, China.

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http://dx.doi.org/10.13345/j.cjb.160484DOI Listing
July 2017

Obtaining a Panel of Cascade Promoter-5'-UTR Complexes in Escherichia coli.

ACS Synth Biol 2017 06 9;6(6):1065-1075. Epub 2017 Mar 9.

Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, and ‡National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University , 1800 Lihu Road, Wuxi, Jiangsu 214122, China.

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http://dx.doi.org/10.1021/acssynbio.7b00006DOI Listing
June 2017

Identification of a polysaccharide produced by the pyruvate overproducer Candida glabrata CCTCC M202019.

Appl Microbiol Biotechnol 2017 Jun 25;101(11):4447-4458. Epub 2017 Mar 25.

School of Biotechnology and Key Laboratory of Industrial Biotechnology, Ministry of Education, Jiangnan University, 1800 Lihu Road, Wuxi, Jiangsu, 214122, China.

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http://dx.doi.org/10.1007/s00253-017-8245-1DOI Listing
June 2017

[Optimization of heparosan synthetic pathway in Bacillus subtilis 168].

Sheng Wu Gong Cheng Xue Bao 2017 Jun;33(6):936-945

Key Laboratory of Industrial Biotechnology, Ministry of Education, Jiangnan University, Wuxi 214122, Jiangsu, China.

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http://dx.doi.org/10.13345/j.cjb.160453DOI Listing
June 2017

A high-throughput screening procedure for enhancing pyruvate production in Candida glabrata by random mutagenesis.

Bioprocess Biosyst Eng 2017 May 24;40(5):693-701. Epub 2017 Jan 24.

School of Biotechnology and Key Laboratory of Industrial Biotechnology, Ministry of Education, Jiangnan University, 1800 Lihu Road, Wuxi, Jiangsu, 214122, China.

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http://dx.doi.org/10.1007/s00449-017-1734-xDOI Listing
May 2017

Characterization and application of endogenous phase-dependent promoters in Bacillus subtilis.

Appl Microbiol Biotechnol 2017 May 14;101(10):4151-4161. Epub 2017 Feb 14.

The Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, 214122, China.

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http://dx.doi.org/10.1007/s00253-017-8142-7DOI Listing
May 2017

Scarless assembly of unphosphorylated DNA fragments with a simplified DATEL method.

Bioengineered 2017 May;8(3):296-301

a The Key Laboratory of Industrial Biotechnology, Ministry of Education , School of Biotechnology, Jiangnan University , Wuxi , China.

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http://dx.doi.org/10.1080/21655979.2017.1308986DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470510PMC
May 2017

Microbial response to environmental stresses: from fundamental mechanisms to practical applications.

Appl Microbiol Biotechnol 2017 May 13;101(10):3991-4008. Epub 2017 Apr 13.

Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi, 214122, China.

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http://dx.doi.org/10.1007/s00253-017-8264-yDOI Listing
May 2017

Alginate Particles with Ovalbumin (OVA) Peptide Can Serve as a Carrier and Adjuvant for Immune Therapy in B16-OVA Cancer Model.

Med Sci Monit Basic Res 2017 Apr 28;23:166-172. Epub 2017 Apr 28.

School of Biochemical Engineering, Anhui Polytechnic University, Wuhu, Anhui, China (mainland).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421747PMC
April 2017

P, a Low-pH-Induced Promoter, as a Tool for Dynamic Control of Gene Expression for Metabolic Engineering of Aspergillus niger.

Appl Environ Microbiol 2017 03 2;83(6). Epub 2017 Mar 2.

Key Laboratory of Industrial Biotechnology, Ministry of Education, Jiangnan University, Wuxi, China.

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http://dx.doi.org/10.1128/AEM.03222-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335535PMC
March 2017

Mutant Potential Ubiquitination Sites in Dur3p Enhance the Urea and Ethyl Carbamate Reduction in a Model Rice Wine System.

J Agric Food Chem 2017 Mar 16;65(8):1641-1648. Epub 2017 Feb 16.

Key Laboratory of Industrial Biotechnology, Ministry of Education and School of Biotechnology, Jiangnan University , 1800 Lihu Road, Wuxi, Jiangsu 214122, China.

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http://pubs.acs.org/doi/10.1021/acs.jafc.6b05348
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http://dx.doi.org/10.1021/acs.jafc.6b05348DOI Listing
March 2017

UvrA expression of NZ9000 improve multiple stresses tolerance and fermentation of lactic acid against salt stress.

J Food Sci Technol 2017 Mar 22;54(3):639-649. Epub 2017 Feb 22.

Key Laboratory of Industrial Biotechnology, Ministry of Education, Jiangnan University, Wuxi, Jiangsu 214122 People's Republic of China.

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http://dx.doi.org/10.1007/s13197-017-2493-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334222PMC
March 2017

The application of powerful promoters to enhance gene expression in industrial microorganisms.

World J Microbiol Biotechnol 2017 Feb 2;33(2):23. Epub 2017 Jan 2.

Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, 1800 Lihu Road, Wuxi, 214122, Jiangsu, China.

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http://dx.doi.org/10.1007/s11274-016-2184-3DOI Listing
February 2017

Recent advances of molecular toolbox construction expand Pichia pastoris in synthetic biology applications.

World J Microbiol Biotechnol 2017 Jan 30;33(1):19. Epub 2016 Nov 30.

The Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, 214122, China.

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http://dx.doi.org/10.1007/s11274-016-2185-2DOI Listing
January 2017

Comparative genomics and transcriptome analysis of Aspergillus niger and metabolic engineering for citrate production.

Sci Rep 2017 01 20;7:41040. Epub 2017 Jan 20.

Key Laboratory of Industrial Biotechnology, Ministry of Education, Jiangnan University, Wuxi 214122, China.

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http://dx.doi.org/10.1038/srep41040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5247736PMC
January 2017

[Stability enhancement of urethanase from Lysinibacillus fusiformis by site-directed mutagenesis].

Sheng Wu Gong Cheng Xue Bao 2016 Sep;32(9):1233-1242

Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, Jiangsu, China.

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http://doi.cnki.net/Resolution/Handler?doi=10.13345/j.cjb.15
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http://dx.doi.org/10.13345/j.cjb.150527DOI Listing
September 2016