Gunter Kuhnle

Gunter Kuhnle

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Gunter Kuhnle

Publications by authors named "Gunter Kuhnle"

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Sugar intake among German adolescents: trends from 1990-2016 based on biomarker excretion in 24-h urine samples.

Br J Nutr 2020 Feb 27:1-23. Epub 2020 Feb 27.

Institute of Nutritional and Food Sciences -Nutritional Epidemiology, University of Bonn, DONALD Study, Heinstück 11, 44225Dortmund, Germany;

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http://dx.doi.org/10.1017/S0007114520000665DOI Listing
February 2020

Stable isotope ratios-nutritional biomarkers of long-term intake?

Am J Clin Nutr 2019 Dec;110(6):1265-1267

Department of Food and Nutritional Sciences, University of Reading, Reading, United Kingdom.

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http://dx.doi.org/10.1093/ajcn/nqz239DOI Listing
December 2019

Impact of high drinking water nitrate levels on the endogenous formation of apparent N-nitroso compounds in combination with meat intake in healthy volunteers.

Environ Health 2019 10 17;18(1):87. Epub 2019 Oct 17.

Department of Toxicogenomics, GROW-school for Oncology and Developmental Biology, Maastricht University Medical Center, P.O Box 616, 6200, MD, Maastricht, the Netherlands.

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http://dx.doi.org/10.1186/s12940-019-0525-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796425PMC
October 2019

Oat bran, but not its isolated bioactive β-glucans or polyphenols, have a bifidogenic effect in an in vitro fermentation model of the gut microbiota.

Br J Nutr 2019 03 28;121(5):549-559. Epub 2019 Jan 28.

1Department of Food and Nutritional Sciences, School of Chemistry,Food and Pharmacy,The University of Reading,Reading RG6 6AP,UK.

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http://dx.doi.org/10.1017/S0007114518003501DOI Listing
March 2019

Dietary Intervention Modifies DNA Methylation Age Assessed by the Epigenetic Clock.

Mol Nutr Food Res 2018 12 2;62(23):e1800092. Epub 2018 Nov 2.

Human Nutrition Research Centre, Institute of Cellular Medicine, Newcastle University, Newcastle Upon Tyne, NE2 4HH, UK.

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http://dx.doi.org/10.1002/mnfr.201800092DOI Listing
December 2018

Stable Isotope Ratios: Nutritional Biomarker and More.

J Nutr 2018 12;148(12):1883-1885

Department of Food and Nutritional Sciences, University of Reading, Reading, United Kingdom.

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http://dx.doi.org/10.1093/jn/nxy247DOI Listing
December 2018

Supplementation of the Diet by Exogenous Myrosinase via Mustard Seeds to Increase the Bioavailability of Sulforaphane in Healthy Human Subjects after the Consumption of Cooked Broccoli.

Mol Nutr Food Res 2018 09 26;62(18):e1700980. Epub 2018 Jul 26.

Department of Food and Nutritional Sciences, University of Reading, Whiteknights, Reading, RG6 6AP, UK.

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http://dx.doi.org/10.1002/mnfr.201700980DOI Listing
September 2018

Nutrition epidemiology of flavan-3-ols: The known unknowns.

Mol Aspects Med 2018 06 16;61:2-11. Epub 2017 Nov 16.

Department of Food & Nutritional Sciences, Harry Nursten Building, University of Reading, Reading RG6 6UR, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.mam.2017.10.003DOI Listing
June 2018

Red Wine and Pomegranate Extracts Suppress Cured Meat Promotion of Colonic Mucin-Depleted Foci in Carcinogen-Induced Rats.

Nutr Cancer 2017 Feb-Mar;69(2):289-298. Epub 2017 Jan 17.

a INRA UMR1331, TOXALIM (Research Center in Food Toxicology), Université de Toulouse, ENVT, INP , Toulouse , France.

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http://dx.doi.org/10.1080/01635581.2017.1263745DOI Listing
January 2018

Sulfate, nitrate and blood pressure - An EPIC interaction between sulfur and nitrogen.

Pharmacol Res 2017 Aug 10;122:127-129. Epub 2017 Jun 10.

Clinical & Experimental Sciences, Medicine and NIHR Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, SO16 6YD, UK. Electronic address:

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http://dx.doi.org/10.1016/j.phrs.2017.06.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507251PMC
August 2017

Flavonoid intake in European adults (18 to 64 years).

PLoS One 2015 26;10(5):e0128132. Epub 2015 May 26.

Department of Food & Nutritional Sciences, University of Reading, Reading, United Kingdom; Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0128132PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444122PMC
April 2016

Key bioactive reaction products of the NO/H2S interaction are S/N-hybrid species, polysulfides, and nitroxyl.

Proc Natl Acad Sci U S A 2015 Aug 29;112(34):E4651-60. Epub 2015 Jul 29.

Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton General Hospital and Institute for Life Sciences, Southampton SO16 6YD, United Kingdom;

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http://dx.doi.org/10.1073/pnas.1509277112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4553758PMC
August 2015

A central role for heme iron in colon carcinogenesis associated with red meat intake.

Cancer Res 2015 Mar 15;75(5):870-9. Epub 2015 Jan 15.

INRA UMR1331; TOXALIM (Research Center in Food Toxicology); Université de Toulouse; ENVT; INP; UPS; TOXALIM; Toulouse, France.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-2554DOI Listing
March 2015

Reply to KJ Petzke.

Am J Clin Nutr 2015 Mar;101(3):688

From the MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge, UK (PSP; NGF, e-mail: the University of Reading, Reading, UK (GGCK); and the Department of Archaeology and Anthropology and the McDonald Institute for Archaeological Research, University of Cambridge, Cambridge, UK (TCO).

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http://dx.doi.org/10.3945/ajcn.114.103309DOI Listing
March 2015

Estimated dietary intakes and sources of flavanols in the German population (German National Nutrition Survey II).

Eur J Nutr 2014 6;53(2):635-43. Epub 2013 Aug 6.

Department of Food and Nutritional Sciences, University of Reading, Reading, RG6 6AP, UK.

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http://dx.doi.org/10.1007/s00394-013-0572-0DOI Listing
October 2014

Estimated intake of dietary phyto-oestrogens in Australian women and evaluation of correlates of phyto-oestrogen intake.

J Nutr Sci 2012 5;1:e11. Epub 2012 Sep 5.

Population Health Department , Queensland Institute of Medical Research , 300 Herston Road, Herston, Brisbane, QLD 4006 , Australia.

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http://www.journals.cambridge.org/abstract_S2048679012000110
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http://dx.doi.org/10.1017/jns.2012.11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153304PMC
September 2014

O⁶-carboxymethylguanine DNA adduct formation and lipid peroxidation upon in vitro gastrointestinal digestion of haem-rich meat.

Mol Nutr Food Res 2014 Sep 2;58(9):1883-96. Epub 2014 Jul 2.

Laboratory of Chemical Analysis, Department of Veterinary Public Health and Food Safety, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.

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http://dx.doi.org/10.1002/mnfr.201400078DOI Listing
September 2014

Serum carbon and nitrogen stable isotopes as potential biomarkers of dietary intake and their relation with incident type 2 diabetes: the EPIC-Norfolk study.

Am J Clin Nutr 2014 Aug 2;100(2):708-18. Epub 2014 Jul 2.

From the MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, United Kingdom (PSP, AJMC, SB, NJW, and NGF); the Department of Archaeology & Anthropology, University of Cambridge, Downing Street, Cambridge, United Kingdom (TCO); the McDonald Institute for Archaeological Research, University of Cambridge, Downing Street, Cambridge, United Kingdom (TCO and CKK); the University of Reading, Reading, United Kingdom (GGCK); and the Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom (AMM, RNL, K-TK, and GGCK).

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http://dx.doi.org/10.3945/ajcn.113.068577DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4095667PMC
August 2014

Calcium and α-tocopherol suppress cured-meat promotion of chemically induced colon carcinogenesis in rats and reduce associated biomarkers in human volunteers.

Am J Clin Nutr 2013 Nov 11;98(5):1255-62. Epub 2013 Sep 11.

Université de Toulouse, French National Institute For Agricultural Research, Joint Research Unit 1331 Xénobiotiques, Toulouse, France (FHFP, OCBM, RLS, ST, NN, FG, MA, JD, and DEC); the French Pork and Pig Institute-Institut du Porc, Paris, France (RLS and J-LV); the INRA, UMR 1019, Human Nutrition Unit, Research Center for Human Nutrition Auvergne, Clermont-Ferrrand, France (NM, DA, and NC); the University hospital Clermont-Ferrand, Service de Nutrition, Clermont-Ferrrand, France (NM and NC); the Eppley Institute for Research in Cancer, University of Nebraska Medical Center, Omaha, NE (SSM); and the Department of Food and Nutritional Sciences, University of Reading, Reading, United Kingdom (GCGK).

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http://dx.doi.org/10.3945/ajcn.113.061069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798078PMC
November 2013

Markers for nutrition studies: review of criteria for the evaluation of markers.

Eur J Nutr 2013 Oct 17;52(7):1685-99. Epub 2013 Aug 17.

Jan de Vries, De Vries Nutrition Solutions, Reuvekamp 26, 7213-CE, Gorssel, The Netherlands.

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http://dx.doi.org/10.1007/s00394-013-0553-3DOI Listing
October 2013

Intakes and sources of isoflavones, lignans, enterolignans, coumestrol and soya-containing foods in the Norfolk arm of the European Prospective Investigation into Cancer and Nutrition (EPIC-Norfolk), from 7 d food diaries, using a newly updated database.

Public Health Nutr 2013 Aug 3;16(8):1454-62. Epub 2012 Sep 3.

European Prospective Investigation of Cancer, Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Worts Causeway, Cambridge CB1 8RN, UK.

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http://dx.doi.org/10.1017/S1368980012003904DOI Listing
August 2013

Carbon and nitrogen isotopic ratios of urine and faeces as novel nutritional biomarkers of meat and fish intake.

Eur J Nutr 2013 Feb 10;52(1):389-95. Epub 2012 Mar 10.

Department of Food and Nutritional Sciences, University of Reading, Whiteknights, PO Box 226, Reading, RG6 6AP, UK.

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http://dx.doi.org/10.1007/s00394-012-0328-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549402PMC
February 2013

A multilevel analytical approach for detection and visualization of intracellular NO production and nitrosation events using diaminofluoresceins.

Free Radic Biol Med 2012 Dec 28;53(11):2146-58. Epub 2012 Sep 28.

Cardiovascular Research Laboratory, Department of Cardiology, Pneumology, and Angiology, Medical Faculty, Heinrich Heine University, Düsseldorf 40225, Germany.

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http://dx.doi.org/10.1016/j.freeradbiomed.2012.09.008DOI Listing
December 2012

Structurally related (-)-epicatechin metabolites in humans: assessment using de novo chemically synthesized authentic standards.

Free Radic Biol Med 2012 Apr 23;52(8):1403-12. Epub 2011 Dec 23.

Department of Nutrition, University of California at Davis, Davis, CA 95616, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S089158491101254
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http://dx.doi.org/10.1016/j.freeradbiomed.2011.12.010DOI Listing
April 2012

Nutritional biomarkers for objective dietary assessment.

J Sci Food Agric 2012 Apr 20;92(6):1145-9. Epub 2012 Feb 20.

Department of Food and Nutritional Sciences, University of Reading, Reading RG6 6 AH, UK.

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http://doi.wiley.com/10.1002/jsfa.5631
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http://dx.doi.org/10.1002/jsfa.5631DOI Listing
April 2012

Association between dietary phyto-oestrogens and bone density in men and postmenopausal women.

Br J Nutr 2011 Oct 17;106(7):1063-9. Epub 2011 May 17.

Department of Food and Nutritional Sciences, University of Reading, Whiteknights, PO Box 226, Reading RG6 6AP, UK.

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http://dx.doi.org/10.1017/S0007114511001309DOI Listing
October 2011

Phytoestrogen consumption and association with breast, prostate and colorectal cancer in EPIC Norfolk.

Arch Biochem Biophys 2010 Sep 1;501(1):170-5. Epub 2010 Jun 1.

MRC Centre for Nutritional Epidemiology in Cancer Prevention and Survival, Department for Public Health and Primary Care, University of Cambridge, UK.

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http://dx.doi.org/10.1016/j.abb.2010.05.018DOI Listing
September 2010

Effect of dietary meat and fish on endogenous nitrosation, inflammation and genotoxicity of faecal water.

Mutagenesis 2010 May 27;25(3):243-7. Epub 2010 Jan 27.

MRC Dunn Human Nutrition Unit, Wellcome Trust/MRC Building, Hills Road, Cambridge CB2 0XY, UK.

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http://dx.doi.org/10.1093/mutage/gep070DOI Listing
May 2010

Breast, colorectal, and prostate cancer risk in the European Prospective Investigation into Cancer and Nutrition-Norfolk in relation to phytoestrogen intake derived from an improved database.

Am J Clin Nutr 2010 Feb 9;91(2):440-8. Epub 2009 Dec 9.

MRC Centre for Nutrition and Cancer, Department of Public Health and Primary Care, Strangeways Research Laboratory, Wort's Causeway, Cambridge, United Kingdom.

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http://dx.doi.org/10.3945/ajcn.2009.28282DOI Listing
February 2010

Effect of processed and red meat on endogenous nitrosation and DNA damage.

Carcinogenesis 2009 Aug 4;30(8):1402-7. Epub 2009 Jun 4.

MRC Dunn Human Nutrition Unit, Wellcome Trust/MRC Building, Hills Road, Cambridge CB2 0XY, UK.

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http://dx.doi.org/10.1093/carcin/bgp130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718076PMC
August 2009

Phytoestrogen content of cereals and cereal-based foods consumed in the UK.

Nutr Cancer 2009 ;61(3):302-9

MRC Dunn Human Nutrition Unit, Wellcome Trust/MRC Building, Hills Road, Cambridge CB2 0XY, UK.

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http://dx.doi.org/10.1080/01635580802567141DOI Listing
June 2009

Phytoestrogen content of foods of animal origin: dairy products, eggs, meat, fish, and seafood.

J Agric Food Chem 2008 Nov 16;56(21):10099-104. Epub 2008 Oct 16.

MRC Dunn Human Nutrition Unit, Wellcome Trust/MRC Building, Hills Road, Cambridge CB2 0XY, United Kingdom.

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http://dx.doi.org/10.1021/jf801344xDOI Listing
November 2008

Lack of prospective associations between plasma and urinary phytoestrogens and risk of prostate or colorectal cancer in the European Prospective into Cancer-Norfolk study.

Cancer Epidemiol Biomarkers Prev 2008 Oct;17(10):2891-4

MRC Centre for Nutrition and Cancer, Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge, Strangeways Research Laboratory, Wort's Causeway, Cambridge CB1 8RN, United Kingdom.

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http://dx.doi.org/10.1158/1055-9965.EPI-08-0335DOI Listing
October 2008

Phytoestrogen content of beverages, nuts, seeds, and oils.

J Agric Food Chem 2008 Aug 1;56(16):7311-5. Epub 2008 Aug 1.

MRC Dunn Human Nutrition Unit, Wellcome Trust/MRC Building, Hills Road, Cambridge CB2 0XY, United Kingdom.

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http://pubs.acs.org/doi/abs/10.1021/jf801534g
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http://dx.doi.org/10.1021/jf801534gDOI Listing
August 2008

Breast cancer risk in relation to urinary and serum biomarkers of phytoestrogen exposure in the European Prospective into Cancer-Norfolk cohort study.

Breast Cancer Res 2008 17;10(2):R32. Epub 2008 Apr 17.

MRC Centre for Nutrition and Cancer, Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge, Strangeways Research Laboratory, Wort's Causeway, Cambridge, CB1 8RN, UK.

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http://dx.doi.org/10.1186/bcr1995DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2397534PMC
July 2008

Flavanol monomer-induced changes to the human faecal microflora.

Br J Nutr 2008 Apr 1;99(4):782-92. Epub 2007 Nov 1.

Molecular Nutrition Group, School of Chemistry, Food and Pharmacy, University of Reading, Reading RG2 6AP, UK.

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http://dx.doi.org/10.1017/S0007114507853384DOI Listing
April 2008

Extraction and quantification of phytoestrogens in foods using automated solid-phase extraction and LC/MS/MS.

Anal Chem 2007 Dec 2;79(23):9234-9. Epub 2007 Nov 2.

MRC Dunn Human Nutrition Unit, Wellcome Trust/MRC Building, Hills Road, Cambridge CB2 0XY, UK.

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http://dx.doi.org/10.1021/ac701732rDOI Listing
December 2007

Diet-induced endogenous formation of nitroso compounds in the GI tract.

Free Radic Biol Med 2007 Oct 13;43(7):1040-7. Epub 2007 Mar 13.

MRC Dunn Human Nutrition Unit, Wellcome Trust/MRC Building, Hills Road, Cambridge CB2 2XY, UK.

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http://dx.doi.org/10.1016/j.freeradbiomed.2007.03.011DOI Listing
October 2007

The reaction of flavonoid metabolites with peroxynitrite.

Biochem Biophys Res Commun 2006 Dec 2;350(4):960-8. Epub 2006 Oct 2.

Molecular Nutrition Group, School of Chemistry, Food and Pharmacy, University of Reading, Reading RG2 6AP, UK.

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http://dx.doi.org/10.1016/j.bbrc.2006.09.131DOI Listing
December 2006

Distribution of [3H]trans-resveratrol in rat tissues following oral administration.

Br J Nutr 2006 Jul;96(1):62-70

School of Food Biosciences, University of Reading, Whiteknights, Reading RG6 6AP, UK.

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http://dx.doi.org/10.1079/bjn20061810DOI Listing
July 2006

Absorption, tissue distribution and excretion of pelargonidin and its metabolites following oral administration to rats.

Br J Nutr 2006 Jan;95(1):51-8

Antioxidant Research Group, Wolfson Centre for Age-Related Diseases, GKT School of Biomedical Sciences, King's College, London SE1 9RT, UK.

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http://dx.doi.org/10.1079/bjn20051596DOI Listing
January 2006

The genotypic variation of the antioxidant potential of different tomato varieties.

Free Radic Res 2005 Sep;39(9):1005-16

Antioxidant Research Group, Wolfson Centre for Age-Related Disease, GKT School of Biomedical Science, King's College London, London SE1 9RT, UK.

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http://dx.doi.org/10.1080/10715760400022293DOI Listing
September 2005

The differential tissue distribution of the citrus flavanone naringenin following gastric instillation.

Free Radic Res 2004 Dec;38(12):1329-40

Antioxidant Research Group, Wolfson Centre for Age-Related Diseases, GKT School of Biomedical Sciences, King's College, London, SE1 9RT UK.

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http://dx.doi.org/10.1080/10715760400017293DOI Listing
December 2004

Colonic metabolism of dietary polyphenols: influence of structure on microbial fermentation products.

Free Radic Biol Med 2004 Jan;36(2):212-25

Antioxidant Research Group, Wolfson Centre for Age-Related Diseases, School of Biomedical Sciences, King's College London, SE1 9RT, London, UK.

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http://dx.doi.org/10.1016/j.freeradbiomed.2003.09.022DOI Listing
January 2004

Hesperetin glucuronide, a photoprotective agent arising from flavonoid metabolism in human skin fibroblasts.

Photochem Photobiol 2003 Sep;78(3):256-61

Antioxidant Research Group, Wolfson Centre for Age-Related Diseases, GKT School of Biomedical Sciences, King's College London, St. Thomas' Street, London SE1 9RT, UK.

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http://dx.doi.org/10.1562/0031-8655(2003)078<0256:hgapaa>2.0.co;2DOI Listing
September 2003

Intracellular metabolism and bioactivity of quercetin and its in vivo metabolites.

Biochem J 2003 May;372(Pt 1):173-81

Wolfson Centre for Age-Related Diseases, GKT School of Biomedical Sciences, Hodgkin Building, King's College, Guy's Campus, London SE1 9RT, U.K.

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http://dx.doi.org/10.1042/BJ20021972DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1223367PMC
May 2003

Interaction between flavonoids and the blood-brain barrier: in vitro studies.

J Neurochem 2003 Apr;85(1):180-92

Antioxidant Research Group, Wolfson Center for Age-Related Diseases, Centre for Neuroscience Research, Guy's, King's and St Thomas's School of Biomedical Sciences, King's College, London, UK.

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http://dx.doi.org/10.1046/j.1471-4159.2003.01652.xDOI Listing
April 2003

Uptake and metabolism of epicatechin and its access to the brain after oral ingestion.

Free Radic Biol Med 2002 Dec;33(12):1693-702

Antioxidant Research Group, Wolfson Centre for Age-Related Diseases, GKT School of Biomedical Sciences, King's College, London, England, UK.

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http://dx.doi.org/10.1016/s0891-5849(02)01137-1DOI Listing
December 2002

The metabolism of dietary polyphenols and the relevance to circulating levels of conjugated metabolites.

Free Radic Res 2002 Nov;36(11):1229-41

Antioxidant Research Group, Wolfson Centre for Age-Related Diseases, Guy's, King's and St. Thomas's School of Biomedical Sciences, King's College London, Guy's Campus, Hodgkin Building-3rd Floor, London SE1 9RT, UK.

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http://dx.doi.org/10.1080/246-1071576021000016472DOI Listing
November 2002

The metabolic fate of dietary polyphenols in humans.

Free Radic Biol Med 2002 Jul;33(2):220-35

Antioxidant Research Group, Wolfson Centre for Age-Related Diseases, School of Biomedical Sciences, King's College London, UK.

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http://dx.doi.org/10.1016/s0891-5849(02)00877-8DOI Listing
July 2002