Professor of Experimental Neurology
Lund | Sweden
Main Specialties: Neurology
Additional Specialties: dementia, behavioural neurology
Gunnar Keppler Gouras (GK Gouras or G Gouras in papers) is Professor of Experimental Neurology & head of the Neurobiology section in the Department of Experimental Medical Science, Lund University in Lund, Sweden. His research focuses on the cellular and synaptic biology and pathology of Alzheimer’s disease (AD)-linked beta-amyloid (Abeta). Abeta was traditionally viewed as an extracellular peptide that abnormally aggregates in AD. His publication Gouras GK et al., 2000, provided the first evidence that particularly disease-linked Abeta accumulates early within vulnerable neurons in AD. Utilising immuno-electron microscopy his group then discovered that Abeta localises to multivesicular bodies and with AD preferentially accumulates and aggregates in synaptic terminals, providing the 1st physical link between Abeta and synapses (Takahashi RH et al., 2002; 2004, 2010).
Primary Affiliation: Lund University - Lund , Sweden
PubMed Central Citations
2243PubMed Central Citations
Sci Rep 2018 Aug 27;8(1):12836. Epub 2018 Aug 27.
Department of Medical Biochemistry and Biophysics, Umeå University, 90187, Umeå, Sweden.
J Neurochem 2015 Nov 17;135(3):606-15. Epub 2015 Sep 17.
Karolinska Institutet, Department of Neurobiology, Care Science and Society, Division of Neurogeriatrics, Center for Alzheimer Research, Huddinge, Sweden.
Neurosci Lett 2014 Apr 3;566:125-30. Epub 2014 Mar 3.
Karolinska Institutet, Department of Neurobiology, Care Science and Society, Center for Alzheimer Research, Novum level 5, 141 86 Stockholm, Sweden. Electronic address:
Life Sci 2012 Dec 19;91(23-24):1153-8. Epub 2012 Jun 19.
Experimental Dementia Research Unit, BMC-B12, Wallenberg Neuroscience Center, Department of Experimental Medical Science, Lund University, Sölvegatan 19, 221 84 Lund, Sweden.
Methods Mol Biol 2011 ;793:343-50
Experimental Dementia Research Unit, Department of Experimental Medical Science, Wallenberg Neuroscience Center, Lund University, Lund, Sweden.
Neurobiol Aging 2005 Oct;26(9):1235-44
Laboratory of Alzheimer's disease Neurobiology, Department of Neurology & Neuroscience, Weill Medical College of Cornell University, 525 East 68th Street, New York, NY 10021, USA.
Proc Natl Acad Sci U S A 2003 Jan 9;100(2):721-6. Epub 2003 Jan 9.
Fisher Center for Research on Alzheimer's Disease, Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA.
J Neurosci 2001 Apr;21(8):2561-70
Laboratory of Molecular and Cellular Neuroscience, Fisher Center for Research on Alzheimer Disease, and Laboratory for Mass Spectrometry, The Rockefeller University, New York, New York 10021, USA.
Ann N Y Acad Sci 1991 ;640:102-9
Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205-2181.