Gunnar H Heine

Gunnar H Heine

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Gunnar H Heine

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Plasma FGF23 does not rise during physical exercise as a physiological model of sympathetic activation.

Clin Res Cardiol 2019 Mar 8;108(3):341-343. Epub 2018 Aug 8.

Internal Medicine IV, Nephrology and Hypertension, Saarland University Medical Center, Homburg, Germany.

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http://dx.doi.org/10.1007/s00392-018-1347-7DOI Listing
March 2019

[The Cardiorenal Syndrome].

Dtsch Med Wochenschr 2019 03 14;144(6):382-386. Epub 2019 Mar 14.

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http://dx.doi.org/10.1055/a-0661-4456DOI Listing
March 2019

[The Cardiorenal Syndrome].

Dtsch Med Wochenschr 2019 03 28;144(6):e2. Epub 2019 Mar 28.

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http://dx.doi.org/10.1055/a-0884-5458DOI Listing
March 2019

Strength of Fibroblast Growth Factor 23 as a Cardiovascular Risk Predictor in Chronic Kidney Disease Weaken by ProBNP Adjustment.

Am J Nephrol 2019 26;49(3):203-211. Epub 2019 Feb 26.

Department of Nephrology and Hypertension, Internal Medicine IV, Saarland University Medical Center, Homburg, Germany.

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http://dx.doi.org/10.1159/000497125DOI Listing
February 2019

Do plasma neprilysin activity and plasma neprilysin concentration predict cardiac events in chronic kidney disease patients?

Nephrol Dial Transplant 2019 01;34(1):100-108

Department of Internal Medicine IV, Saarland University Medical Center, Homburg, Germany.

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http://dx.doi.org/10.1093/ndt/gfy066DOI Listing
January 2019

Erratum.

Nephrol Dial Transplant 2019 Jan 21. Epub 2019 Jan 21.

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http://dx.doi.org/10.1093/ndt/gfy408DOI Listing
January 2019

L-Homoarginine and its AGXT2-metabolite GOCA in chronic kidney disease as markers for clinical status and prognosis.

Amino Acids 2018 Oct 7;50(10):1347-1356. Epub 2018 Jul 7.

Institute of Clinical Pharmacology, Otto-von-Guericke University, Leipziger Str. 44, 39120, Magdeburg, Germany.

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http://dx.doi.org/10.1007/s00726-018-2610-yDOI Listing
October 2018

In Reply.

Authors:
Gunnar H Heine

Dtsch Arztebl Int 2018 09;155(37):606-607

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http://dx.doi.org/10.3238/arztebl.2018.0606bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206395PMC
September 2018

HDL functionality and cardiovascular outcome among nondialysis chronic kidney disease patients.

J Lipid Res 2018 07 22;59(7):1256-1265. Epub 2018 May 22.

Otto Loewi Research Center, Division of Pharmacology, Medical University of Graz, Graz, Austria

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http://dx.doi.org/10.1194/jlr.P085076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027904PMC
July 2018

Corrigendum: FGF23 in Cardiovascular Disease: Innocent Bystander or Active Mediator?

Front Endocrinol (Lausanne) 2018 18;9:422. Epub 2018 Jul 18.

Department of Cardiology, University Hospital of the RWTH Aachen, Aachen, Germany.

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http://dx.doi.org/10.3389/fendo.2018.00422DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058598PMC
July 2018

FGF23 in Cardiovascular Disease: Innocent Bystander or Active Mediator?

Front Endocrinol (Lausanne) 2018 27;9:351. Epub 2018 Jun 27.

Department of Cardiology, University Hospital of the RWTH Aachen, Aachen, Germany.

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http://dx.doi.org/10.3389/fendo.2018.00351DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036253PMC
June 2018

Validation of echocardiographic criteria for the clinical diagnosis of heart failure in chronic kidney disease.

Nephrol Dial Transplant 2018 04;33(4):653-660

Department of Internal Medicine IV, Nephrology and Hypertension, Saarland University Medical Center and Saarland University Faculty of Medicine, Homburg, Germany.

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http://dx.doi.org/10.1093/ndt/gfx197DOI Listing
April 2018

Association of Nonoxidized Parathyroid Hormone with Cardiovascular and Kidney Disease Outcomes in Chronic Kidney Disease.

Clin J Am Soc Nephrol 2018 04 5;13(4):569-576. Epub 2018 Mar 5.

Department of Internal Medicine IV-Nephrology and Hypertension, Saarland University Medical Centre, Homburg, Germany.

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http://dx.doi.org/10.2215/CJN.06620617DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968904PMC
April 2018

Oral Anticoagulation in Chronic Kidney Disease and Atrial Fibrillation.

Dtsch Arztebl Int 2018 04;115(17):287-294

Saarland University Medical Center, Saarland University Faculty of Medicine, Internal Medicine IV - Nephrology and Hypertension, Homburg; Department of Cardiology, University Hospital RWTH Aachen; Saarland University Medical Center, Saarland University Faculty of Medicine, Internal Medicine III - Cardiology, Angiology, Intensive Care Medicine, Homburg.

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http://dx.doi.org/10.3238/arztebl.2018.0287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974258PMC
April 2018

Best Albuminuria Measurement to Predict Cardiovascular and Renal Events.

Am J Nephrol 2016 18;43(5):383-8. Epub 2016 May 18.

Internal Medicine IV - Nephrology and Hypertension, Saarland University Medical Center, Homburg, Germany.

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http://dx.doi.org/10.1159/000446483DOI Listing
January 2018

Still a reasonable goal: Targeting cholesterol in dialysis and advanced chronic kidney disease patients.

Semin Dial 2017 09 19;30(5):390-394. Epub 2017 Jun 19.

Institute of Experimental and Clinical Pharmacology, Medical University of Graz, Graz, Austria.

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http://dx.doi.org/10.1111/sdi.12621DOI Listing
September 2017

Hydration and contrast-induced kidney injury.

Lancet 2017 07 27;390(10093):452. Epub 2017 Jul 27.

Department for Internal Medicine III, Cardiology, Angiology and Intensive Care Medicine, Saarland University Medical Center, Homburg 66421, Germany.

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http://dx.doi.org/10.1016/S0140-6736(17)31815-9DOI Listing
July 2017

Letter to the Editor regarding Dounousi E et al. Intact FGF23 and α-Klotho during acute inflammation/sepsis in CKD patients.

Eur J Clin Invest 2017 06;47(6):468-469

Internal Medicine IV - Nephrology and Hypertension, Saarland University Faculty of Medicine, Saarland University Medical Center, Homburg, Germany.

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http://dx.doi.org/10.1111/eci.12761DOI Listing
June 2017

The systemic nature of CKD.

Nat Rev Nephrol 2017 06 24;13(6):344-358. Epub 2017 Apr 24.

INSERM U970, Hopital Européen Georges Pompidou, 20 Rue Leblanc, 75015 Paris, France.

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http://dx.doi.org/10.1038/nrneph.2017.52DOI Listing
June 2017

Reprint of: MicroRNA profiling of human intermediate monocytes.

Immunobiology 2017 06 31;222(6):831-840. Epub 2017 May 31.

Department of Internal Medicine IV, Saarland University Medical Center, Homburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.imbio.2017.05.003DOI Listing
June 2017

MicroRNA profiling of human intermediate monocytes.

Immunobiology 2017 03 13;222(3):587-596. Epub 2016 Nov 13.

Department of Internal Medicine IV, Saarland University Medical Center, Homburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.imbio.2016.11.006DOI Listing
March 2017

Erratum.

Nephrol Dial Transplant 2017 01;32(1):202

Department of Nephrology and Hypertension, Internal Medicine IV, Saarland University Medical Center and Saarland University Faculty of Medicine, Homburg, Germany.

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http://dx.doi.org/10.1093/ndt/gfw435DOI Listing
January 2017

NT-proBNP and Echocardiographic Parameters for Prediction of Cardiovascular Outcomes in Patients with CKD Stages G2-G4.

Clin J Am Soc Nephrol 2016 11 11;11(11):1978-1988. Epub 2016 Aug 11.

Internal Medicine IV, Nephrology and Hypertension, Saarland University Medical Center, Homburg, Germany;

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http://dx.doi.org/10.2215/CJN.01660216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108187PMC
November 2016

Impact of individual intravenous iron preparations on the differentiation of monocytes towards macrophages and dendritic cells.

Nephrol Dial Transplant 2016 11 24;31(11):1835-1845. Epub 2016 Mar 24.

Department of Internal Medicine IV - Nephrology and Hypertension, Saarland University Medical Center, Homburg, Germany.

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http://dx.doi.org/10.1093/ndt/gfw045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5091613PMC
November 2016

Response of fibroblast growth factor 23 to volume interventions in arterial hypertension and diabetic nephropathy.

Medicine (Baltimore) 2016 Nov;95(46):e5003

aDivision of Nephrology, Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands bDepartment of Internal Medicine IV, Nephrology and Hypertension, Saarland University Medical Center, Homburg, Germany cDepartment of Nephrology, VU Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1097/MD.0000000000005003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120892PMC
November 2016

Blood-Pressure and Cholesterol Lowering in the HOPE-3 Trial.

N Engl J Med 2016 09;375(12):1190

Saarland University Medical Center, Homburg, Germany

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http://dx.doi.org/10.1056/NEJMc1608916DOI Listing
September 2016

Hypertension in Chronic Kidney Disease Part 2: Role of Ambulatory and Home Blood Pressure Monitoring for Assessing Alterations in Blood Pressure Variability and Blood Pressure Profiles.

Hypertension 2016 06 2;67(6):1102-10. Epub 2016 May 2.

From the Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (G.P., J.E.O.); Department of Cardiovascular, Neural and Metabolic Sciences, San Luca Hospital, IRCCS Istituto Auxologico Italiano, Milan, Italy (G.P., J.E.O., G.B.); Indiana University and VAMC, Indianapolis (R.A.); Clinic of Nephrology, C. I. Parhon University Hospital, Gr. T. Popa University of Medicine and Pharmacy, Iasi, Romania (A.C.); Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands (F.W.D.); Department of Internal Medicine IV, Saarland University Medical Centre, Homburg, Saarland, Germany (D.F., G.H.H.); European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) Registry, Department of Medical Informatics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (K.J.J.); CNR, Institute of Clinical Physiology, Pisa, Italy (L.G., E.P., R.S.); Division of Nephrology, Department of Medicine, Koc University School of Medicine, Istanbul, Turkey (M.K.); Nephrology, Dialysis and Transplantation Unit and CNR-IFC Clinical Epidemiology and Pathophysiology of Renal Diseases and Hypertension, Reggio Calabria, Italy (F.M., C.Z.); Division of Nephrology, Ambroise Paré Hospital, Assistance Publique Hôpitaux de Paris, Boulogne-Billancourt, Paris, France; University of Paris Ouest -Versailles-Saint-Quentin-en-Yvelines (UVSQ), and Inserm U-1018, Centre de recherche en épidémiologie et santé des populations (CESP), Equipe 5, Villejuif; Paris-Sud University (PSU) and University of Paris Ouest-Versailles-Saint-Quentin-en-Yvelines (UVSQ), F-CRIN-INI-CRCT, Paris, France (Z.M.); IIS-Fundación Jiménez Díaz, Universidad Autónoma de Madrid, Fundación Renal Iñigo Alvarez de Toledo, Madrid, Spain (A.O.); Inserm, Centre d'Investigations Cliniques-Plurithématique 1433, Inserm U1116, Nancy, France (P.R.); CHU Nancy, Département de Cardiologie, Institut Lorrain du Cœur et des Vaisseaux, Vandoeuvre lès

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.115.06896DOI Listing
June 2016

Hypertension in Chronic Kidney Disease Part 1: Out-of-Office Blood Pressure Monitoring: Methods, Thresholds, and Patterns.

Hypertension 2016 06 2;67(6):1093-101. Epub 2016 May 2.

From the Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy (G.P., J.E.O.); Department of Cardiovascular, Neural and Metabolic Sciences, San Luca Hospital, IRCCS Istituto Auxologico Italiano, Milan, Italy (G.P., J.E.O., G.B.); Indiana University and VAMC, Indianapolis (R.A.); Clinic of Nephrology, C. I. Parhon University Hospital, Gr. T. Popa University of Medicine and Pharmacy, Iasi, Romania (A.C.); Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands (F.W.D.); Department of Internal Medicine IV, Saarland University Medical Centre, Homburg, Saarland, Germany (D.F., G.H.H.); European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) Registry, Department of Medical Informatics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (K.J.J.); CNR, Institute of Clinical Physiology, Pisa, Italy (L.G., E.P., R.S.); Division of Nephrology, Department of Medicine, Koc University School of Medicine, Istanbul, Turkey (M.K.); Nephrology, Dialysis and Transplantation Unit and CNR-IFC Clinical Epidemiology and Pathophysiology of Renal Diseases and Hypertension, Reggio Calabria, Italy (F.M., C.Z.); Division of Nephrology, Ambroise Paré Hospital, Assistance Publique Hôpitaux de Paris, Boulogne-Billancourt, Paris, France; University of Paris Ouest-Versailles-Saint-Quentin-en-Yvelines (UVSQ), and Inserm U-1018, Centre de recherche en épidémiologie et santé des populations (CESP), Equipe 5, Villejuif; Paris-Sud University (PSU) and University of Paris Ouest-Versailles-Saint-Quentin-en-Yvelines (UVSQ), F-CRIN-INI-CRCT, Paris, France (Z.M.); IIS-Fundación Jiménez Díaz, Universidad Autónoma de Madrid, Fundación Renal Iñigo Alvarez de Toledo, Madrid, Spain (A.O.); Inserm, Centre d'Investigations Cliniques-Plurithématique 1433, Inserm U1116, Nancy, France (P.R.); CHU Nancy, Département de Cardiologie, Institut Lorrain du Cœur et des Vaisseaux, Vandoeuvre lès

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.115.06895DOI Listing
June 2016

The Kinetics of Circulating Monocyte Subsets and Monocyte-Platelet Aggregates in the Acute Phase of ST-Elevation Myocardial Infarction: Associations with 2-Year Cardiovascular Events.

Medicine (Baltimore) 2016 May;95(18):e3466

From the Tianjin Key Laboratory of Cardiovascular Remodeling and Target Organ Injury (XZ, X-LL, W-JJ, J-XL, Z-ZG, DR, Y-QM, SZ, Z-WX, H-XL, Y-ML), Pingjin Hospital Heart Center, Logistics University of Chinese People's Armed Police Forces, Tianjin, China; Division of Community Health and Humanities (PPW), Faculty of Medicine, Memorial University of Newfoundland, Newfoundland and Labrador, Canada; Department of Radiology (ZZ); Feinberg Cardiovascular Research Institute (BCB, DCL); Department of Pathology (EBT), Northwestern University Feinberg School of Medicine, Chicago, IL, USA; and Department of Internal Medicine IV (AMZ and GHH), Nephrology and Hypertension, Saarland University Medical Center, Homburg, Germany.

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http://dx.doi.org/10.1097/MD.0000000000003466DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863763PMC
May 2016

External Validation of the Kidney Failure Risk Equation and Re-Calibration with Addition of Ultrasound Parameters.

Clin J Am Soc Nephrol 2016 Apr 19;11(4):609-15. Epub 2016 Jan 19.

Department of Nephrology and Hypertension, Internal Medicine IV, Nephrology and Hypertension, Saarland University Medical Center and Saarland University Faculty of Medicine, Homburg, Germany;

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http://dx.doi.org/10.2215/CJN.08110715DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822670PMC
April 2016

Clinical management of the uraemic syndrome in chronic kidney disease.

Lancet Diabetes Endocrinol 2016 Apr 3;4(4):360-73. Epub 2016 Mar 3.

Investigation Network Initiative Cardiovascular and Renal Clinical Trialists (INI-CRCT), French Clinical Research Infrastructure Network (F-CRIN), Nancy, France; INSERM U970, Hôpital Européen Georges Pompidou, Paris.

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http://www.thelancet.com/pdfs/journals/landia/PIIS2213-8587(
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http://linkinghub.elsevier.com/retrieve/pii/S221385871600033
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http://dx.doi.org/10.1016/S2213-8587(16)00033-4DOI Listing
April 2016

Ferric pyrophosphate: good things come to those who wait?

Nephrol Dial Transplant 2015 Dec 21;30(12):1942-4. Epub 2015 Jul 21.

Department of Internal Medicine IV, Saarland University Medical Center, Homburg, Germany.

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http://dx.doi.org/10.1093/ndt/gfv287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832995PMC
December 2015

Comparison of two different strategies for human monocyte subsets gating within the large-scale prospective CARE FOR HOMe Study.

Cytometry A 2015 Aug 9;87(8):750-8. Epub 2015 Jun 9.

Department of Internal Medicine IV - Nephrology and Hypertension, Saarland University Medical Center, Homburg, Germany.

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http://doi.wiley.com/10.1002/cyto.a.22703
Publisher Site
http://dx.doi.org/10.1002/cyto.a.22703DOI Listing
August 2015

Validity of Vascular Calcification as a Screening Tool and as a Surrogate End Point in Clinical Research.

Hypertension 2015 Jul 11;66(1):3-9. Epub 2015 May 11.

From the CNR-IFC Pathophysiology of Renal Diseases and Hypertension Unit, Reggio Calabria, Italy (C.Z., D.B., G.D'A., F.M., G.T.); Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands (F.W.D.); Department of Internal Medicine IV, Saarland University Medical Centre, Homburg/Saar, Germany (D.F., G.H.H.); Department of Medical Informatics, Academic Medical Center, European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) Registry, University of Amsterdam, Amsterdam, The Netherlands (K.J.J.); Division of Nephrology, Department of Medicine, Koc University School of Medicine, Istanbul, Turkey (M.K.); Nephrology, Dialysis, and Transplantation Unit and CNR-IFC Clinical Epidemiology, Reggio Calabria, Italy (F.M.); Paris Ile de France Ouest (UVSQ) University, Paris, France (Z.M.); Fundación Jiménez Díaz, Universidad Autónoma de Madrid, Fundación Renal Iñigo Alvarez de Toledo, Madrid, Spain (A.O.); Department of Cardiovascular, Neural, and Metabolic Sciences, S. Luca Hospital, Istituto Auxologico Italiano & University of Milan-Bicocca, Milan, Italy (G.P.); INSERM, Centre d'Investigations Cliniques-Plurithématique 1433, INSERM U1116, Nancy, France (P.R.); Département de Cardiologie, CHU Nancy, Institut Lorrain du Cœur et des Vaisseaux, Vandoeuvre lès Nancy, France (P.R.); Université de Lorraine, Nancy, France (P.R.); INI-CRCT (Cardiovascular and Renal Clinical Trialists), French-Clinical Research Infrastructure Network (F-CRIN), Nancy, France (P.R.); Division of Nephrology, Department of Internal Medicine, Ghent University Hospital, University Hospital Gent, Ghent, Belgium (R.V.); Department of Nephrology, Endocrinology and Metabolic Diseases, Medical University of Silesia, Katowice, Poland (A.W.); and INSERM U970, Hopital Européen Georges Pompidou, Paris, France (G.L.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.115.04801DOI Listing
July 2015

Mineral metabolism in heart disease.

Authors:
Gunnar H Heine

Curr Opin Nephrol Hypertens 2015 Jul;24(4):310-6

Internal Medicine IV - Nephrology and Hypertension, Saarland University Medical Center, Homburg, Germany.

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http://dx.doi.org/10.1097/MNH.0000000000000129DOI Listing
July 2015

Will too much kidney function kill you: just as none at all?

Nephrol Dial Transplant 2015 Jun;30(6):869-70

Saarland University Medical Center, D-66421 Homburg, Germany.

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http://dx.doi.org/10.1093/ndt/gfv126DOI Listing
June 2015

Immunosuppression and monocyte subsets.

Nephrol Dial Transplant 2015 Jan 13;30(1):143-53. Epub 2014 Oct 13.

Department of Internal Medicine IV, Saarland University Medical Center, Homburg, Germany.

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http://dx.doi.org/10.1093/ndt/gfu315DOI Listing
January 2015

Carbamylated low-density lipoprotein induces endothelial dysfunction.

Eur Heart J 2014 Nov 21;35(43):3021-32. Epub 2014 Mar 21.

University Heart Center, Cardiovascular Center, University Hospital Zurich, Rämistrasse 100, 8091 Zurich, Switzerland Center of Molecular Cardiology, Schlieren Campus, University of Zurich, Zurich, Switzerland

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http://dx.doi.org/10.1093/eurheartj/ehu111DOI Listing
November 2014

Association of vascular endothelial factors with cardiovascular outcome and mortality in chronic kidney disease patients: a 4-year cohort study.

Atherosclerosis 2014 Oct 12;236(2):360-5. Epub 2014 Aug 12.

Division of Renal Diseases and Hypertension, The George Washington University School of Medicine, Washington, DC, USA. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2014.07.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4327843PMC
October 2014

Influence of cholecalciferol supplementation in hemodialysis patients on monocyte subsets: a randomized, double-blind, placebo-controlled clinical trial.

Nephron Clin Pract 2013 29;123(3-4):209-19. Epub 2013 Aug 29.

Internal Medicine II, Martin Luther University of Halle-Wittenberg Medical Centre, Halle, Germany.

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http://dx.doi.org/10.1159/000354717DOI Listing
September 2014

Lower Apo A-I and lower HDL-C levels are associated with higher intermediate CD14++CD16+ monocyte counts that predict cardiovascular events in chronic kidney disease.

Arterioscler Thromb Vasc Biol 2014 Sep 24;34(9):2120-7. Epub 2014 Jul 24.

From the Department of Internal Medicine III, Cardiology, Angiology and Intensive Care Medicine (K.S.R., M.B) and Department of Internal Medicine IV, Nephrology and Hypertension (K.S.R., A.M.Z., I.E., S.S., D.F., G.H.H.), Saarland University Medical Center, Homburg, Germany; and Department of Medicine, Imperial College London, London, United Kingdom (K.J.W.).

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http://dx.doi.org/10.1161/ATVBAHA.114.304172DOI Listing
September 2014

Associations of FGF-23 and sKlotho with cardiovascular outcomes among patients with CKD stages 2-4.

Clin J Am Soc Nephrol 2014 Jun 27;9(6):1049-58. Epub 2014 Mar 27.

Department of Internal Medicine IV-Nephrology and Hypertension, Saarland University Medical Centre, Homburg, Germany;

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http://dx.doi.org/10.2215/CJN.07870713DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046724PMC
June 2014

Decline in estimated glomerular filtration rate and subsequent risk of end-stage renal disease and mortality.

JAMA 2014 Jun;311(24):2518-2531

Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21205, USA (J Coresh, K Matsushita, Y Sang, SH Ballew); Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada (TC Turin); Johns Hopkins Medical Institutions, Baltimore, MD, 21205 (LJ Appel); The George Institute for Global Health, University of Sydney, Sydney, NSW, Australia (H Arima); Department of Nephrology and Transplantation, Royal Prince Alfred Hospital, Sydney, NSW, Australia and Sydney Medical School, University of Sydney, Sydney, NSW, Australia (SJ Chadban); Department of Medicine, University of Salerno, Salerno, Italy (M Cirillo); BC Provincial Renal Agency, Vancouver, Canada (O Djurdjev); Nephrology Department, Geisinger Medical Center, Danville, PA, USA (JA Green); Department of Internal Medicine IV-Nephrology and Hypertension, Saarland University Medical Center, D-66421 Homburg, Germany (GH Heine); Division of Nephrology at Tufts Medical Center, Boston, MA 02111, USA (LA Inker, AS Levey); Department of Health and Welfare, Ibaraki Prefectural Office, Mito, Japan (F Irie); Minneapolis VA Health Care System and Department of Medicine, University of Minnesota, Minneapolis, MN, USA (A Ishani); University of California San Diego, San Diego, CA, USA (JH Ix); Memphis Veterans Affairs Medical Center and University of Tennessee Health Science Center, Memphis, TN, USA (CP Kovesdy); Division of Applied Health Sciences, University of Aberdeen, and NHS Grampian, Foresterhill, Aberdeen, UK (A Marks); Department of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo, Japan, Department of Planning for Drug Development and Clinical Evaluation, Tohoku University Graduate School of Pharmaceutical Sciences, Sendai, Japan, and Department of Health Science, Shiga University of Medical Science, Setatuskinowa, Otsu, Japan (T Ohkubo); Medical Informatics Department, Maccabi Healthcare Services, and Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (V Shalev); Department of Family Medicine and Population Health, Virginia Commonwealth University, School of Medicine, 830 E. Main Street, P.O. Box 980212, Richmond, VA 23298-0212 (A Shankar); China Medical University Hospital, Taichung, Taiwan and Institute of Population Health Science, National Health Research Institutes, Zhunan, Taiwan (CP Wen); Department of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands (PE de Jong, RT Gansevoort); Dialysis Unit, University Hospital of The Ryukyus, 207 Uehara, Nishihara, Okinawa 903-0215, Japan (K Iseki); Inserm U1018, CESP Center for Research in Epidemiology and Population Health, Villejuif, France and UMRS 1018, Paris-Sud University, Villejuif, France (B Stengel).

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http://aura.abdn.ac.uk/bitstream/2164/5421/1/ESRD_ACM_CKD_pr
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http://jama.jamanetwork.com/article.aspx?doi=10.1001/jama.20
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http://dx.doi.org/10.1001/jama.2014.6634DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172342PMC
June 2014

S-adenosylhomocysteine is associated with subclinical atherosclerosis and renal function in a cardiovascular low-risk population.

Atherosclerosis 2014 May 18;234(1):17-22. Epub 2014 Feb 18.

Department of Internal Medicine IV, Saarland University Medical Center, Homburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2014.02.002DOI Listing
May 2014

Distinct immunologic effects of different intravenous iron preparations on monocytes.

Nephrol Dial Transplant 2014 Apr 11;29(4):809-22. Epub 2014 Feb 11.

Department of Internal Medicine IV - Nephrology and Hypertension, Saarland University Medical Center, Homburg, Germany.

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http://dx.doi.org/10.1093/ndt/gft524DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967833PMC
April 2014

Single FGF-23 measurement and time-averaged plasma phosphate levels in hemodialysis patients.

Clin J Am Soc Nephrol 2013 Oct 11;8(10):1764-72. Epub 2013 Jul 11.

Department for Internal Medicine IV-Nephrology and Hypertension, Saarland University Medical Center, Homburg, Germany, †Psychological Institute, Humboldt-Universität zu Berlin, Berlin, Germany.

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http://dx.doi.org/10.2215/CJN.13021212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789357PMC
October 2013

FGF-23 is associated with increased disease severity and early mortality in cardiogenic shock.

Eur Heart J Acute Cardiovasc Care 2013 Sep;2(3):211-8

Klinik für Innere Medizin III, Kardiologie, Angiologie und Internistische Intensivmedizin, Universitätsklinikum des Saarlandes, Germany.

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http://dx.doi.org/10.1177/2048872613494025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821824PMC
September 2013

Clinical relevance of epigenetic dysregulation in chronic kidney disease-associated cardiovascular disease.

Nephrol Dial Transplant 2013 Jul 19;28(7):1663-71. Epub 2013 Mar 19.

Department of Internal Medicine IV, Saarland University Medical Center, D-66421 Homburg, Germany.

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http://dx.doi.org/10.1093/ndt/gft042DOI Listing
July 2013

Calcium and phosphate impact cardiovascular risk.

Eur Heart J 2013 Apr 28;34(15):1112-21. Epub 2012 Oct 28.

Internal Medicine IV, Nephrology and Hypertension, Saarland University Medical Center, Homburg D-66421, Germany.

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http://dx.doi.org/10.1093/eurheartj/ehs353DOI Listing
April 2013

Plasma Klotho is not related to kidney function and does not predict adverse outcome in patients with chronic kidney disease.

Kidney Int 2013 Jan 15;83(1):121-8. Epub 2012 Aug 15.

Department of Internal Medicine IV - Nephrology and Hypertension, Saarland University Hospital, Homburg/Saar, Germany.

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http://dx.doi.org/10.1038/ki.2012.288DOI Listing
January 2013

T-cell numbers and antigen-specific T-cell function follow different circadian rhythms.

J Clin Immunol 2012 Dec 15;32(6):1381-9. Epub 2012 Jul 15.

Department of Internal Medicine IV, Saarland University, Homburg, Germany.

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http://dx.doi.org/10.1007/s10875-012-9730-zDOI Listing
December 2012

Monocyte heterogeneity in human cardiovascular disease.

Immunobiology 2012 Dec 25;217(12):1273-84. Epub 2012 Jul 25.

Department of Internal Medicine IV, Saarland University Medical Center, Homburg, Germany.

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http://dx.doi.org/10.1016/j.imbio.2012.07.001DOI Listing
December 2012

Does the measurement of the difference of resistive indexes in spleen and kidney allow a selective assessment of chronic kidney injury?

Radiology 2012 Sep 6;264(3):894-902. Epub 2012 Jul 6.

Department of Internal Medicine IV-Nephrology and Hypertension, Saarland University Hospital, Kirrberger Strasse, 66421 Homburg/Saar, Germany.

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http://dx.doi.org/10.1148/radiol.12111533DOI Listing
September 2012

Ultrasound renal resistive index is not an organ-specific predictor of allograft outcome.

Nephrol Dial Transplant 2012 Aug 30;27(8):3315-20. Epub 2012 Jan 30.

Department of Internal Medicine IV, Saarland University Hospital, Homburg, Germany.

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http://dx.doi.org/10.1093/ndt/gfr805DOI Listing
August 2012

FGF-23: the rise of a novel cardiovascular risk marker in CKD.

Nephrol Dial Transplant 2012 Aug;27(8):3072-81

Department of Internal Medicine IV—Nephrology and Hypertension, Saarland University Medical Center, Homburg/Saar, Germany.

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https://academic.oup.com/ndt/article-lookup/doi/10.1093/ndt/
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http://dx.doi.org/10.1093/ndt/gfs259DOI Listing
August 2012

Cholesterol synthesis, cholesterol absorption, and mortality in hemodialysis patients.

Clin J Am Soc Nephrol 2012 Jun 29;7(6):943-8. Epub 2012 Mar 29.

Department of Internal Medicine IV, Nephrology and Hypertension, Saarland University Medical Center, Homburg, Germany.

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http://dx.doi.org/10.2215/CJN.05170511DOI Listing
June 2012

CKD-associated atherosclerosis and monocyte heterogeneity.

Kidney Int 2012 Mar;81(6):599; author reply 599-600

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http://dx.doi.org/10.1038/ki.2011.433DOI Listing
March 2012

SuperSAGE evidence for CD14++CD16+ monocytes as a third monocyte subset.

Blood 2011 Sep 29;118(12):e50-61. Epub 2011 Jul 29.

Department of Internal Medicine IV, Saarland University Hospital, Homburg/Saar, Germany.

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http://dx.doi.org/10.1182/blood-2011-01-326827DOI Listing
September 2011

Monocyte angiotensin converting enzyme expression may be associated with atherosclerosis rather than arteriosclerosis in hemodialysis patients.

Clin J Am Soc Nephrol 2011 Mar 2;6(3):505-11. Epub 2010 Dec 2.

Department of Internal Medicine II, Martin Luther University, Halle-Wittenberg, Germany.

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http://dx.doi.org/10.2215/CJN.06870810DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082407PMC
March 2011

CD14++CD16+ monocytes and cardiovascular outcome in patients with chronic kidney disease.

Eur Heart J 2011 Jan 12;32(1):84-92. Epub 2010 Oct 12.

Department of Internal Medicine IV, Saarland University Hospital, Homburg/Saar, Germany.

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http://dx.doi.org/10.1093/eurheartj/ehq371DOI Listing
January 2011

FGF-23 and future cardiovascular events in patients with chronic kidney disease before initiation of dialysis treatment.

Nephrol Dial Transplant 2010 Dec 3;25(12):3983-9. Epub 2010 Jun 3.

Department of Internal Medicine IV, University of Saarland, Homburg, Germany.

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http://dx.doi.org/10.1093/ndt/gfq309DOI Listing
December 2010

The relationships of markers of cholesterol homeostasis with carotid intima-media thickness.

PLoS One 2010 Oct 18;5(10):e13467. Epub 2010 Oct 18.

Klinik für Innere Medizin III, Kardiologie, Angiologie und Internistische Intensivmedizin, Universitätsklinikum des Saarlandes, Homburg/Saar, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0013467PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956704PMC
October 2010

Successful outcome of kidney transplantation from a HBV-DNA positive donor into recipients with cleared HBV-infection using a pre-emptive therapy approach.

J Clin Virol 2010 Sep 24;49(1):53-7. Epub 2010 Jul 24.

Department of Transplant and Infection Immunology, Institute of Virology, Saarland University, D-66421 Homburg, Germany.

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http://dx.doi.org/10.1016/j.jcv.2010.06.020DOI Listing
September 2010

Circulating monocyte subpopulations with high expression of angiotensin-converting enzyme predict mortality in patients with end-stage renal disease.

Nephrol Dial Transplant 2010 Jul 10;25(7):2265-72. Epub 2010 Feb 10.

Department of Internal Medicine II, Martin Luther University of Halle-Wittenberg, Halle, Germany.

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http://dx.doi.org/10.1093/ndt/gfq012DOI Listing
July 2010

Human monocyte heterogeneity--a nephrological perspective.

Nephrol Ther 2010 Jul 5;6(4):219-25. Epub 2010 May 5.

Saarland University Hospital, Department of Internal Medicine IV, Nephrology and Hypertension, 66421 Homburg, Germany.

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http://linkinghub.elsevier.com/retrieve/pii/S176972551000060
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http://dx.doi.org/10.1016/j.nephro.2010.01.008DOI Listing
July 2010

Indices of systemic atherosclerosis are superior to ultrasound resistance indices for prediction of allograft survival.

Nephrol Dial Transplant 2010 Apr 26;25(4):1294-300. Epub 2009 Nov 26.

Department of Internal Medicine IV, University of Saarland, Homburg, Germany.

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http://dx.doi.org/10.1093/ndt/gfp631DOI Listing
April 2010

Monocyte heterogeneity in obesity and subclinical atherosclerosis.

Eur Heart J 2010 Feb 17;31(3):369-76. Epub 2009 Aug 17.

Department of Internal Medicine IV, Saarland University Hospital, Homburg 66421, Germany.

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http://dx.doi.org/10.1093/eurheartj/ehp308DOI Listing
February 2010

Clinical relevance of FGF-23 in chronic kidney disease.

Kidney Int Suppl 2009 Dec(114):S34-42

Department of Internal Medicine IV-Renal and Hypertensive Disease, Saarland University Medical Centre, Homburg/Saar, Germany.

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http://dx.doi.org/10.1038/ki.2009.405DOI Listing
December 2009

Haemodialysis-induced transient CD16+ monocytopenia and cardiovascular outcome.

Nephrol Dial Transplant 2009 Nov 8;24(11):3480-6. Epub 2009 Jul 8.

Department of Internal Medicine IV, Saarland University Hospital, Homburg/Saar, Germany.

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http://dx.doi.org/10.1093/ndt/gfp287DOI Listing
November 2009