Publications


Risk Stratification of Patients With Current Generation Continuous-Flow Left Ventricular Assist Devices Being Bridged to Heart Transplantation.
ASAIO J 2017 Sep 5. Epub 2017 Sep 5.
From the *Houston Methodist DeBakey Heart & Vascular Center, Houston, Texas; †Houston Methodist Research Institute, Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas; ‡Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts; §Department of Surgery, Houston Methodist Hospital, Houston, Texas; ¶Department of Pharmacology, Therapeutics and Toxicology, Universitat Autonoma de Barcelona, Barcelona, Spain; ‖Department of Clinical Pharmacology, Hospital Universitari Germans Trias I Pujol, Badalona, Barcelona, Spain; #Catedra de Cardiologia y Medicina Vascular, Tecnologico de Monterrey, Nuevo Leon, Mexico.




Melding a High-Risk Patient for Continuous Flow Left Ventricular Assist Device into a Low-Risk Patient.
ASAIO J 2017 Nov/Dec;63(6):704-712
From the *Houston Methodist Hospital, Houston, Texas; †Methodist DeBakey Heart and Vascular Center, Houston, Texas; and ‡Catedra de Cardiología y Medicina Vascular, Tecnológico de Monterrey, Monterrey, México.

Role of Adaptive Immunity in the Development and Progression of Heart Failure: New Evidence.
Arch Med Res 2017 Jan;48(1):1-11
Cátedra de Cardiología y Medicina Vascular, Escuela de Medicina, Tecnologico de Monterrey, Monterrey, México; Centro de Investigación Biomédica, Hospital Zambrano Hellion, Tecnologico de Monterrey, San Pedro Garza-García, México; Methodist DeBakey Heart and Vascular Center, The Methodist Hospital, Houston, Texas.



Combination of angiotensin II and l-NG-nitroarginine methyl ester exacerbates mitochondrial dysfunction and oxidative stress to cause heart failure.
Am J Physiol Heart Circ Physiol 2016 Mar 8;310(6):H667-80. Epub 2016 Jan 8.
Center for Bioenergetics, Houston Methodist Research Institute, Weill Cornell Medical College, Houston, Texas;

Rnd3/RhoE Modulates Hypoxia-Inducible Factor 1α/Vascular Endothelial Growth Factor Signaling by Stabilizing Hypoxia-Inducible Factor 1α and Regulates Responsive Cardiac Angiogenesis.
Hypertension 2016 Mar 18;67(3):597-605. Epub 2016 Jan 18.
From the Department of Obstetrics and Gynecology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China (X.Y., Y.Y.); Texas A&M University Health Science Center, Institute of Biosciences and Technology, Houston (X.Y., X.L., T.Y., X.Y., Y.D., K.C.A., J.C.); Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, Hubei, China (X.Y., X.J., X.L.); Cardiovascular Disease and Research Institute, Affiliated Hospital of Hainan Medical College, Haikou, Hainan, China (T.L., J.G.); Department of Pediatrics, Indiana University School of Medicine, Indianapolis (J.S., L.W.); and Methodist DeBakey Heart and Vascular Center, The Methodist Hospital, Houston, TX (K.A.Y., G.T.-A.).


Differential Mitochondrial Function in Remodeled Right and Nonremodeled Left Ventricles in Pulmonary Hypertension.
J Card Fail 2016 Jan 12;22(1):73-81. Epub 2015 Sep 12.
Bioenergetics Program, Houston Methodist Research Institute, Weill Cornell Medical College, Houston, Texas; Department of Medicine, Houston Methodist Research Institute, Weill Cornell Medical College, Houston, Texas. Electronic address:

Impact of pre-operative coronary artery disease on cardiovascular events following lung transplantation.
J Heart Lung Transplant 2016 Jan 4;35(1):115-21. Epub 2015 Sep 4.
Methodist DeBakey Heart & Vascular Center, Houston Methodist Hospital, Houston, Texas; Escuela de Medicina, Tecnologico de Monterrey, Monterrey, Nuevo León, Mexico.

Full Expression of Cardiomyopathy Is Partly Dependent on B-Cells: A Pathway That Involves Cytokine Activation, Immunoglobulin Deposition, and Activation of Apoptosis.
J Am Heart Assoc 2016 Jan 14;5(1). Epub 2016 Jan 14.
Houston Methodist DeBakey Heart & Vascular Center, Houston, TX (A.M.C.R., K.A.Y., J.H.F.A., C.M.O., A.B., J.D.E., G.T.A.) Houston Methodist Hospital Research Institute, Houston, TX (A.M.C.R., K.A.Y., D.J.H., J.D.E., G.T.A.) Catedra de Cardiologia y Medicina Vascular, Tecnológico de Monterrey, Mexico (G.T.A.).

Impaired oxidative metabolism and calcium mishandling underlie cardiac dysfunction in a rat model of post-acute isoproterenol-induced cardiomyopathy.
Am J Physiol Heart Circ Physiol 2015 Mar 19;308(5):H467-77. Epub 2014 Dec 19.
Endowed Chair in Cardiology and Vascular Medicine, School of Medicine, Tecnológico de Monterrey, Monterrey México; Basic and Translational Research Center, Hospital Zambrano-Hellion, TEC Salud, San Pedro, Garza-García, México; and


Persistent blood stream infection in patients supported with a continuous-flow left ventricular assist device is associated with an increased risk of cerebrovascular accidents.
J Card Fail 2015 Feb 6;21(2):119-25. Epub 2014 Nov 6.
Houston Methodist DeBakey Heart and Vascular Center, Houston Methodist Hospital, Houston, Texas; Houston Methodist JC Walter Jr. Transplant Center, Houston Methodist Hospital, Houston, Texas.




Spinal cord stimulation is safe and feasible in patients with advanced heart failure: early clinical experience.
Eur J Heart Fail 2014 Jul 24;16(7):788-95. Epub 2014 Jun 24.
Catedra de Cardiologia y Medicina Vascular, Escuela de Medicina, Tecnológico de Monterrey, México; Houston Methodist DeBakey Heart & Vascular Center, Houston, TX, USA.


Mechanical unloading promotes myocardial energy recovery in human heart failure.
Circ Cardiovasc Genet 2014 Jun 13;7(3):266-76. Epub 2014 May 13.
From the Methodist Diabetes and Metabolism Institute, Houston Methodist Research Institute, Houston, TX (A.A.G., D.J.H., C.J.L., W.A.H.); Department of Systems Medicine and Bioengineering, Houston Methodist Research Institute, Houston, TX (Z.Y., S.T.C.W.); Center for Biostatistics, Houston Methodist Research Institute, Houston, TX (L.E.P.); Department of Medicine, Houston Methodist Hospital, Houston, TX (D.J.H., W.A.H.), Department of Radiology, Houston Methodist Hospital, Houston, TX (S.T.C.W.); Methodist DeBakey Heart and Vascular Institute, Houston, TX (A.M.C.-R., K.A.Y., J.D.E., M.L., G.T.-A.); Weill Cornell Medical College, New York, NY (A.A.G., D.J.H., A.M.C.-R., K.A.Y., Z.Y., J.D.E., M.L., L.E.P., C.J.L., S.T.C.W., G.T.-A., W.A.H.); Sarah W. Stedman Nutrition and Metabolism Center and Departments of Pharmacology and Cancer Biology and Medicine, Duke University Medical Center (R.D.S., B.W., O.L., C.B.N.); Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY (S.T.C.W.); Catedra de Cardiologia, Instituto Tecnologico de Monterrey, Monterrey, Mexico (G.T.-A.); The University of Texas Medical School at Houston, Houston, TX (H.T.).


Freshly isolated mitochondria from failing human hearts exhibit preserved respiratory function.
J Mol Cell Cardiol 2014 Mar 9;68:98-105. Epub 2014 Jan 9.
Bioenergetics Program, Houston Methodist Research Institute, Weill Cornell Medical College, USA; Houston Methodist Hospital Department of Medicine, Weill Cornell Medical College, USA. Electronic address:

Percutaneous placement of an intra-aortic balloon pump in the left axillary/subclavian position provides safe, ambulatory long-term support as bridge to heart transplantation.
JACC Heart Fail 2013 Oct 11;1(5):382-8. Epub 2013 Sep 11.
The Methodist DeBakey Heart & Vascular Center, Department of Cardiology, Houston, Texas; Catedra de Cardiologia y Medicina Vascular, Escuela de Medicina, Tecnologico de Monterrey, Monterrey, Mexico.

Comparison of transendocardial and intracoronary CD34+ cell transplantation in patients with nonischemic dilated cardiomyopathy.
Circulation 2013 Sep;128(11 Suppl 1):S42-9
Advanced Heart Failure and Transplantation Center (B.V., G.P.), Department of Nuclear Medicine (L.L., A.S.), and Department of Hematology (M.S., P.C.), University Medical Center Ljubljana, Ljubljana, Slovenia; National Blood Transfusion Institute, Ljubljana, Slovenia (D.D.); Methodist DeBakey Heart Center, Houston, TX (G.T.-A.); Stanford Cardiovascular Institute (F.H., J.C.W.) and Department of Medicine, Division of Cardiology (B.V., F.H., J.C.W.), Stanford University School of Medicine, Stanford, CA.


Effects of intracoronary CD34+ stem cell transplantation in nonischemic dilated cardiomyopathy patients: 5-year follow-up.
Circ Res 2013 Jan 12;112(1):165-73. Epub 2012 Oct 12.
Advanced Heart Failure and Transplantation Center, Department of Cardiology, Ljubljana University Medical Center, Zaloska 7, Ljubljana, MC SI-1000, Slovenia.

Relationship of right- and left-sided filling pressures in patients with advanced heart failure: a 14-year multi-institutional analysis.
J Heart Lung Transplant 2012 Jan 9;31(1):67-72. Epub 2011 Nov 9.
Division of Cardiology, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9047, USA.




Cardiac improvement during mechanical circulatory support: a prospective multicenter study of the LVAD Working Group.
Circulation 2007 May 7;115(19):2497-505. Epub 2007 May 7.
Albert Einstein College of Medicine, Center for Advanced Cardiac Therapy, 3400 Bainbridge Ave, 7th Floor, Bronx, NY 10467-2490, USA.





Cellular and hemodynamics responses of failing myocardium to continuous flow mechanical circulatory support using the DeBakey-Noon left ventricular assist device: a comparative analysis with pulsatile-type devices.
J Heart Lung Transplant 2005 May;24(5):566-75
Department of Medicine, Thoracic and Cardiovascular Surgery, Section of Cardiology, Methodist DeBakey Heart Center, The Winters Center for Heart Failure Research, Baylor College of Medicine and the Methodist Hospital, Houston 77030, USA.



Altered titin expression, myocardial stiffness, and left ventricular function in patients with dilated cardiomyopathy.
Circulation 2004 Jul 6;110(2):155-62. Epub 2004 Jul 6.
Section of Cardiology, Department of Medicine, Baylor College of Medicine, 6550 Fannin, SM-1256, Houston, TX 77030-2717, USA.

Small Interfering RNA Targeting Mitochondrial Calcium Uniporter Improves Cardiomyocyte Cell Viability in Hypoxia/Reoxygenation Injury by Reducing Calcium Overload.
Oxid Med Cell Longev 2017 27;2017:5750897. Epub 2017 Feb 27.
Cátedra de Cardiología y Medicina Vascular, Escuela de Medicina, Tecnológico de Monterrey, Monterrey, NL, Mexico; Centro de Investigación Biomédica, Hospital Zambrano-Hellion, San Pedro Garza-García, NL, Mexico.

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