Publications by authors named "Guillaume Laval"

33Publications

Recent Adaptive Acquisition by African Rainforest Hunter-Gatherers of the Late Pleistocene Sickle-Cell Mutation Suggests Past Differences in Malaria Exposure.

Am J Hum Genet 2019 03 28;104(3):553-561. Epub 2019 Feb 28.

Human Evolutionary Genetics Unit, Institut Pasteur, UMR 2000 Centre National de la Recherche Scientifique, Paris 75015, France; Center of Bioinformatics, Biostatistics and Integrative Biology, Institut Pasteur, Paris 75015, France. Electronic address:

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March 2019

Deciphering the genetic control of gene expression following Mycobacterium leprae antigen stimulation.

PLoS Genet 2017 Aug 9;13(8):e1006952. Epub 2017 Aug 9.

Program in Infectious Diseases and Immunity in Global Health, The Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.

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August 2017

Genetic Adaptation and Neandertal Admixture Shaped the Immune System of Human Populations.

Cell 2016 Oct;167(3):643-656.e17

Human Evolutionary Genetics Unit, Institut Pasteur, Paris 75015, France; CNRS, URA3012, Paris 75015, France; Center of Bioinformatics, Biostatistics and Integrative Biology, Institut Pasteur, Paris 75015, France. Electronic address:

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October 2016

Genomic Signatures of Selective Pressures and Introgression from Archaic Hominins at Human Innate Immunity Genes.

Am J Hum Genet 2016 Jan;98(1):5-21

Unit of Human Evolutionary Genetics, Institut Pasteur, 75015 Paris, France; CNRS URA3012, 75015 Paris, France. Electronic address:

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January 2016

Detecting Genomic Signatures of Natural Selection with Principal Component Analysis: Application to the 1000 Genomes Data.

Mol Biol Evol 2016 Apr 29;33(4):1082-93. Epub 2015 Dec 29.

TIMC-IMAG UMR 5525, Univ. Grenoble Alpes, Grenoble, France CNRS, TIMC-IMAG, Grenoble, France

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April 2016

Exploring the occurrence of classic selective sweeps in humans using whole-genome sequencing data sets.

Mol Biol Evol 2014 Jul 1;31(7):1850-68. Epub 2014 Apr 1.

Institut Pasteur, Human Evolutionary Genetics, Department of Genomes and Genetics, Paris, FranceCentre National de la Recherche Scientifique, URA3012, Paris, France

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July 2014

Heterogeneous pattern of selective pressure for PRRT2 in human populations, but no association with autism spectrum disorders.

PLoS One 2014 3;9(3):e88600. Epub 2014 Mar 3.

Human Genetics and Cognitive Functions, Institut Pasteur, Paris, France; CNRS URA 2182 'Genes, synapses and cognition', Institut Pasteur, Paris, France; University Denis Diderot Paris 7, Paris, France; Fondation FondaMental, Créteil, France.

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January 2015

Human genetic data reveal contrasting demographic patterns between sedentary and nomadic populations that predate the emergence of farming.

Mol Biol Evol 2013 Dec 24;30(12):2629-44. Epub 2013 Sep 24.

Laboratoire Eco-Anthropologie et Ethnobiologie, UMR 7206, Muséum National d'Histoire Naturelle, Centre National de la Recherche Scientifique, Université Paris 7 Diderot, Paris, France.

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December 2013

The evolutionary landscape of cytosolic microbial sensors in humans.

Am J Hum Genet 2012 Jul 28;91(1):27-37. Epub 2012 Jun 28.

Institut Pasteur, Unit of Human Evolutionary Genetics, Paris, France.

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July 2012

Evolutionary genetic dissection of human interferons.

J Exp Med 2011 Dec 12;208(13):2747-59. Epub 2011 Dec 12.

Unit of Human Evolutionary Genetics, Department of Genomes and Genetics, Institut Pasteur, F-75015 Paris, France.

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December 2011

The selective footprints of viral pressures at the human RIG-I-like receptor family.

Hum Mol Genet 2011 Nov 24;20(22):4462-74. Epub 2011 Aug 24.

Unit of Human Evolutionary Genetics, URA3012, Institut Pasteur, 25-28 Rue du Dr Roux, F-75015 Paris, France.

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November 2011