Guillaume Dorothee

Guillaume Dorothee

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Guillaume Dorothee

Guillaume Dorothee

Publications by authors named "Guillaume Dorothee"

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34Publications

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Glucocorticoid-induced insulin resistance is related to macrophage visceral adipose tissue infiltration.

J Steroid Biochem Mol Biol 2019 01 23;185:150-162. Epub 2018 Aug 23.

Sorbonne Université, INSERM, Centre de Recherche Saint-Antoine, F-75012, Paris, France; Institute of Cardiometabolism and Nutrition (ICAN), F-75013, Paris, France; AP-HP, Department of Pharmacy, Saint-Antoine Hospital, F-75012, Paris, France; University Paris-South, EA4123, F-92296, Châtenay-Malabry, France.

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http://dx.doi.org/10.1016/j.jsbmb.2018.08.010DOI Listing
January 2019

Distinct dynamic profiles of microglial activation are associated with progression of Alzheimer's disease.

Brain 2018 06;141(6):1855-1870

Unit of Neurology of Memory and Language, Université Paris Descartes, Sorbonne Paris Cité, Centre Hospitalier Sainte Anne, Paris, France.

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http://dx.doi.org/10.1093/brain/awy079DOI Listing
June 2018

Neuroinflammation in neurodegeneration: role in pathophysiology, therapeutic opportunities and clinical perspectives.

J Neural Transm (Vienna) 2018 05;125(5):749-750

INSERM, Sorbonne Université, Centre de Recherche Saint-Antoine, CRSA, team "Immune System, Neuroinflammation, Neurodegenerative Diseases", Hôpital Saint-Antoine, 184 Rue du Faubourg Saint-Antoine, 75012, Paris, France.

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http://dx.doi.org/10.1007/s00702-018-1880-6DOI Listing
May 2018

Neutrophil hyperactivation correlates with Alzheimer's disease progression.

Ann Neurol 2018 02;83(2):387-405

Sorbonne Universités, UPMC Univ Paris 06, INSERM, Centre de Recherche Saint-Antoine, team "Immune System, Neuroinflammation and Neurodegenerative Diseases", Hôpital Saint-Antoine, Paris, France.

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http://dx.doi.org/10.1002/ana.25159DOI Listing
February 2018

[Tau and cognitive disorders: a role for T lymphocytes].

Med Sci (Paris) 2017 Oct 10;33(10):817-819. Epub 2017 Oct 10.

Université de Lille, Inserm, CHU-Lille, UMR S 1172, Alzheimer et Tauopathies, LabEx DISTALZ, 1, place de Verdun, 59045 Lille, France.

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http://dx.doi.org/10.1051/medsci/20173310002DOI Listing
October 2017

Beneficial effect of interleukin-2-based immunomodulation in Alzheimer-like pathology.

Brain 2017 07;140(7):e39

INSERM, UMRS 938, CdR Saint-Antoine, Laboratory Immune System, Neuroinflammation and Neurodegenerative Diseases, Hôpital Saint-Antoine, F-75012, Paris, France.

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http://dx.doi.org/10.1093/brain/awx108DOI Listing
July 2017

NOV/CCN3: A New Adipocytokine Involved in Obesity-Associated Insulin Resistance.

Diabetes 2016 09 9;65(9):2502-15. Epub 2016 Jun 9.

Sorbonne Universities, Pierre and Marie Curie University Paris 06, INSERM, Saint-Antoine Research Center, Saint-Antoine Hospital, Paris, France Hospitalo-Universitary Institute, ICAN, Paris, France Department of Endocrinology, Paris, Assistance Publique-Hôpitaux de Paris, Saint-Antoine Hospital, Paris, France

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http://dx.doi.org/10.2337/db15-0617DOI Listing
September 2016

Regulatory T cells delay disease progression in Alzheimer-like pathology.

Brain 2016 Apr 1;139(Pt 4):1237-51. Epub 2016 Feb 1.

1 INSERM, UMRS 938, CdR Saint-Antoine, Laboratory Immune System, Neuroinflammation and Neurodegenerative Diseases, Hôpital St-Antoine, F-75012, Paris, France 2 Sorbonne Universités, UPMC Univ Paris 06, UMRS 938, CdR Saint-Antoine, Hôpital Saint-Antoine, F-75012, Paris, France.

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http://dx.doi.org/10.1093/brain/awv408DOI Listing
April 2016

Early and protective microglial activation in Alzheimer's disease: a prospective study using 18F-DPA-714 PET imaging.

Brain 2016 Apr 15;139(Pt 4):1252-64. Epub 2016 Mar 15.

Unit of Memory and Language, Université Paris Descartes, Sorbonne Paris Cité, Centre de Psychiatrie et Neurosciences, INSERM UMR S894, Centre Hospitalier Sainte Anne, Paris, France

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http://dx.doi.org/10.1093/brain/aww017DOI Listing
April 2016

Vaccine-induced Aβ-specific CD8+ T cells do not trigger autoimmune neuroinflammation in a murine model of Alzheimer's disease.

J Neuroinflammation 2015 May 16;12:95. Epub 2015 May 16.

INSERM, UMR_S 938, CdR Saint-Antoine, Laboratory Immune System, Neuroinflammation and Neurodegenerative Diseases, Inflammation-Immunopathology-Biotherapy Department (DHU i2B), Hôpital Saint-Antoine, 184 rue du Faubourg Saint-Antoine, F-75012, Paris, France.

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http://dx.doi.org/10.1186/s12974-015-0317-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448209PMC
May 2015

Loss of WISP2/CCN5 in estrogen-dependent MCF7 human breast cancer cells promotes a stem-like cell phenotype.

PLoS One 2014 3;9(2):e87878. Epub 2014 Feb 3.

Cancer Biology and Therapeutics, Centre de Recherche Saint-Antoine, Paris, France ; Institut National de la Santé et de la Recherche Médicale, Paris, France ; Université Pierre et Marie Curie, Paris, France.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0087878PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912128PMC
October 2014

Immunotherapy in Alzheimer's disease: do we have all the pieces of the puzzle?

Biol Psychiatry 2013 Sep 14;74(5):329-32. Epub 2013 May 14.

Université Paris Descartes, Sorbonne Paris Cité, France.

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http://dx.doi.org/10.1016/j.biopsych.2013.04.011DOI Listing
September 2013

MHC-independent genetic factors control the magnitude of CD4+ T cell responses to amyloid-β peptide in mice through regulatory T cell-mediated inhibition.

J Immunol 2011 Nov 26;187(9):4492-500. Epub 2011 Sep 26.

INSERM, Unité Mixte de Recherche S 938, Laboratoire Système Immunitaire et Maladies Conformationnelles, Hôpital Saint-Antoine, F-75012 Paris, France.

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http://dx.doi.org/10.4049/jimmunol.1003953DOI Listing
November 2011

[Adaptive immunity to Aβ amyloid peptide in Alzheimer's disease: lessons and perspectives].

Med Sci (Paris) 2011 Nov 30;27(11):938-40. Epub 2011 Nov 30.

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http://dx.doi.org/10.1051/medsci/20112711008DOI Listing
November 2011

Selective depletion of eosinophils or neutrophils in mice impacts the efficiency of apoptotic cell clearance in the thymus.

PLoS One 2010 Jul 6;5(7):e11439. Epub 2010 Jul 6.

Immunology Program, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0011439PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897847PMC
July 2010

MyD88 and Type I interferon receptor-mediated chemokine induction and monocyte recruitment during Listeria monocytogenes infection.

J Immunol 2009 Jul 24;183(2):1271-8. Epub 2009 Jun 24.

Infectious Diseases Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.

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http://dx.doi.org/10.4049/jimmunol.0900460DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2735446PMC
July 2009

In situ sensory adaptation of tumor-infiltrating T lymphocytes to peptide-MHC levels elicits strong antitumor reactivity.

J Immunol 2005 Jun;174(11):6888-97

Laboratoire Cytokines et Immunologie des Tumeurs Humaines, Institut National de la Santé et de la Recherche Médicale Unité 487, Institut Fédératif de Recherche 54, Villejuif, France.

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http://dx.doi.org/10.4049/jimmunol.174.11.6888DOI Listing
June 2005

p53 potentiation of tumor cell susceptibility to CTL involves Fas and mitochondrial pathways.

J Immunol 2005 Jan;174(2):871-8

Laboratoire Cytokines et Immunologie des Tumeurs Humaines, Unité 487 Institut National de la Santé et de la Recherche Médicale, Institut Fédératif de Recherche 54, Institut Gustave Roussy, Villejuif, France.

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http://dx.doi.org/10.4049/jimmunol.174.2.871DOI Listing
January 2005

Mutant alpha-actinin-4 promotes tumorigenicity and regulates cell motility of a human lung carcinoma.

Oncogene 2004 Apr;23(15):2630-9

Laboratoire Cytokines et Immunologie des tumeurs Humaines, U487 INSERM, Institut Fédératif de Recherche 54, Institut Gustave Roussy, F-94805 Villejuif Cedex, France.

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http://dx.doi.org/10.1038/sj.onc.1207347DOI Listing
April 2004

[Tumor/cytotoxic effector cross-talk in the control of tumor susceptibility to lysis].

Bull Cancer 2003 Aug-Sep;90(8-9):686-94

Inserm U487, IFR 54, Institut Gustave-Roussy, 39, rue Camille-Desmoulins, 94805 Villejuif, France.

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December 2003

A three-dimensional tumor cell defect in activating autologous CTLs is associated with inefficient antigen presentation correlated with heat shock protein-70 down-regulation.

Cancer Res 2003 Jul;63(13):3682-7

Centre National de la Recherche Scientifique, Laboratoire d'immunologie des tumeurs, Faculté des sciences pharmaceutiques et biologiques de Paris, Université René Descartes Paris 5, 75006 Paris, France.

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July 2003

Potentiation of a tumor cell susceptibility to autologous CTL killing by restoration of wild-type p53 function.

J Immunol 2003 Jun;170(12):5919-26

Laboratoire Cytokines et Immunologie des Tumeurs Humaines, Institut National de la Santé et de la Recherche Médicale Unité 487, Institut Fédératif de Recherche 54 Institut Gustave Roussy, Villejuif, France.

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http://dx.doi.org/10.4049/jimmunol.170.12.5919DOI Listing
June 2003

Antitumor cytotoxic T-lymphocyte response in human lung carcinoma: identification of a tumor-associated antigen.

Immunol Rev 2002 Oct;188:114-21

Laboratoire Cytokines et Immunologie des tumeurs Humaines, U487 INSERM, Institut Fédératif de Recherche-54, Institut Gustave Roussy, Villejuif, France.

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http://dx.doi.org/10.1034/j.1600-065x.2002.18810.xDOI Listing
October 2002

Cytotoxic T lymphocytes directed against a tumor-specific mutated antigen display similar HLA tetramer binding but distinct functional avidity and tissue distribution.

Proc Natl Acad Sci U S A 2002 Jul 1;99(14):9358-63. Epub 2002 Jul 1.

Laboratoire Cytokines et Immunologie des Tumeurs Humaines, U487 Institut National de la Santé et de la Recherche Médicale, Institut Gustave Roussy, Institut Fédératif de Recherche-54, F-94805 Villejuif, Cedex, France.

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http://www.pnas.org/cgi/doi/10.1073/pnas.142308199
Publisher Site
http://dx.doi.org/10.1073/pnas.142308199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC123145PMC
July 2002

Tumor-infiltrating CD4+ T lymphocytes express APO2 ligand (APO2L)/TRAIL upon specific stimulation with autologous lung carcinoma cells: role of IFN-alpha on APO2L/TRAIL expression and -mediated cytotoxicity.

J Immunol 2002 Jul;169(2):809-17

Laboratoire Cytokines et Immunologie des Tumeurs Humaines, Institut National de la Santé et de la Recherche Médicale Unité 487, Institut Gustave Roussy, Villejuif, France.

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http://dx.doi.org/10.4049/jimmunol.169.2.809DOI Listing
July 2002

Role of p53 in the sensitization of tumor cells to apoptotic cell death.

Mol Immunol 2002 May;38(12-13):977-80

Institut Gustave Roussy, INSERM U.487, 39 Rue Camille Desmoulins, 95805 Villejuif Cedex, France.

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http://dx.doi.org/10.1016/s0161-5890(02)00025-1DOI Listing
May 2002

Drug specific cytotoxic T-cells in the skin lesions of a patient with toxic epidermal necrolysis.

J Invest Dermatol 2002 Apr;118(4):728-33

INSERM U 448 Department of Dermatology, Hôpital H Mondor, Université Paris XII, Créteil, France.

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http://dx.doi.org/10.1046/j.1523-1747.2002.01622.xDOI Listing
April 2002

Wild-type p53 induced sensitization of mutant p53 TNF-resistant cells: role of caspase-8 and mitochondria.

Cancer Gene Ther 2002 Mar;9(3):219-27

INSERM U487, "Cytokines et Immunologie des Tumeurs Humaines," Institut Gustave Roussy, Villejuif 94805, France.

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http://dx.doi.org/10.1038/sj.cgt.7700434DOI Listing
March 2002