Guillaume Bourque

Guillaume Bourque

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Guillaume Bourque

Publications by authors named "Guillaume Bourque"

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A point mutation in the linker domain of mouse STAT5A is associated with impaired NK-cell regulation.

Genes Immun 2019 Oct 8. Epub 2019 Oct 8.

Department of Human Genetics, McGill University, Montreal, QC, H3A 0C7, Canada.

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http://dx.doi.org/10.1038/s41435-019-0088-6DOI Listing
October 2019

eFORGE v2.0: updated analysis of cell type-specific signal in epigenomic data.

Bioinformatics 2019 Jun 4. Epub 2019 Jun 4.

Medical Genomics Group, Paul O'Gorman Building, UCL Cancer Institute, University College London, 72 Huntley Street, London, United Kingdom.

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https://academic.oup.com/bioinformatics/advance-article/doi/
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http://dx.doi.org/10.1093/bioinformatics/btz456DOI Listing
June 2019

A hidden markov model for identifying differentially methylated sites in bisulfite sequencing data.

Biometrics 2019 03 9;75(1):210-221. Epub 2018 Oct 9.

Department of Decision Sciences, HEC Montreal, Quebec, Canada.

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http://doi.wiley.com/10.1111/biom.12965
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http://dx.doi.org/10.1111/biom.12965DOI Listing
March 2019

Computational tools to unmask transposable elements.

Nat Rev Genet 2018 11;19(11):688-704

Department of Human Genetics, McGill University, Montréal, Canada.

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http://dx.doi.org/10.1038/s41576-018-0050-xDOI Listing
November 2018

Comparing Apples to Apples and Oranges to Oranges.

Trends Genet 2018 08 28;34(8):571-572. Epub 2018 May 28.

Department of Human Genetics, McGill University, Montréal, Canada; Canadian Center for Computational Genomics, McGill University, Montréal, Canada; McGill University and Génome Québec Innovation Center, Montréal, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.tig.2018.05.002DOI Listing
August 2018

Human copy number variants are enriched in regions of low mappability.

Nucleic Acids Res 2018 08;46(14):7236-7249

Department of Human Genetics, McGill University, Montréal H3A 1B1, Canada.

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http://dx.doi.org/10.1093/nar/gky538DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101599PMC
August 2018

MetaboAnalyst 4.0: towards more transparent and integrative metabolomics analysis.

Nucleic Acids Res 2018 07;46(W1):W486-W494

Institute of Parasitology, McGill University, Montreal, Québec, Canada.

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http://dx.doi.org/10.1093/nar/gky310DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030889PMC
July 2018

RNA-Seq as a Tool to Study the Tumor Microenvironment.

Methods Mol Biol 2016 ;1458:311-37

Department of Human Genetics, McGill University, Montreal, QC, Canada.

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http://dx.doi.org/10.1007/978-1-4939-3801-8_22DOI Listing
January 2018

Identifying co-opted transposable elements using comparative epigenomics.

Dev Growth Differ 2018 Jan 24;60(1):53-62. Epub 2018 Jan 24.

Department of Human Genetics, McGill University, Montréal, H3A 1B1, Québec, Canada.

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http://dx.doi.org/10.1111/dgd.12423DOI Listing
January 2018

High Rate of Recurrent De Novo Mutations in Developmental and Epileptic Encephalopathies.

Authors:
Fadi F Hamdan Candace T Myers Patrick Cossette Philippe Lemay Dan Spiegelman Alexandre Dionne Laporte Christina Nassif Ousmane Diallo Jean Monlong Maxime Cadieux-Dion Sylvia Dobrzeniecka Caroline Meloche Kyle Retterer Megan T Cho Jill A Rosenfeld Weimin Bi Christine Massicotte Marguerite Miguet Ledia Brunga Brigid M Regan Kelly Mo Cory Tam Amy Schneider Georgie Hollingsworth David R FitzPatrick Alan Donaldson Natalie Canham Edward Blair Bronwyn Kerr Andrew E Fry Rhys H Thomas Joss Shelagh Jane A Hurst Helen Brittain Moira Blyth Robert Roger Lebel Erica H Gerkes Laura Davis-Keppen Quinn Stein Wendy K Chung Sara J Dorison Paul J Benke Emily Fassi Nicole Corsten-Janssen Erik-Jan Kamsteeg Frederic T Mau-Them Ange-Line Bruel Alain Verloes Katrin Õunap Monica H Wojcik Dara V F Albert Sunita Venkateswaran Tyson Ware Dean Jones Yu-Chi Liu Shekeeb S Mohammad Peyman Bizargity Carlos A Bacino Vincenzo Leuzzi Simone Martinelli Bruno Dallapiccola Marco Tartaglia Lubov Blumkin Klaas J Wierenga Gabriela Purcarin James J O'Byrne Sylvia Stockler Anna Lehman Boris Keren Marie-Christine Nougues Cyril Mignot Stéphane Auvin Caroline Nava Susan M Hiatt Martina Bebin Yunru Shao Fernando Scaglia Seema R Lalani Richard E Frye Imad T Jarjour Stéphanie Jacques Renee-Myriam Boucher Emilie Riou Myriam Srour Lionel Carmant Anne Lortie Philippe Major Paola Diadori François Dubeau Guy D'Anjou Guillaume Bourque Samuel F Berkovic Lynette G Sadleir Philippe M Campeau Zoha Kibar Ronald G Lafrenière Simon L Girard Saadet Mercimek-Mahmutoglu Cyrus Boelman Guy A Rouleau Ingrid E Scheffer Heather C Mefford Danielle M Andrade Elsa Rossignol Berge A Minassian Jacques L Michaud

Am J Hum Genet 2017 Nov;101(5):664-685

Centre Hospitalier Universitaire Sainte-Justine Research Center, Montreal, QC H3T1C5, Canada; Department of Neurosciences, Université de Montréal, Montreal, QC H3T1J4, Canada; Department of Pediatrics, Université de Montréal, Montreal, QC H3T1C5, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2017.09.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673604PMC
November 2017

Identification of Elongated Primary Cilia with Impaired Mechanotransduction in Idiopathic Scoliosis Patients.

Sci Rep 2017 03 14;7:44260. Epub 2017 Mar 14.

Viscogliosi Laboratory in Molecular Genetics of Musculoskeletal Diseases, Sainte-Justine University Hospital Research Center, Montreal, Quebec, H3T 1C5, Canada.

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http://dx.doi.org/10.1038/srep44260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349607PMC
March 2017

Conserved expression of transposon-derived non-coding transcripts in primate stem cells.

BMC Genomics 2017 02 28;18(1):214. Epub 2017 Feb 28.

Department of Human Genetics, McGill University, Dr Penfield Avenue, Montreal, H3A 1B1, Canada.

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http://dx.doi.org/10.1186/s12864-017-3568-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331655PMC
February 2017

In Silico Methods to Identify Exapted Transposable Element Families.

Methods Mol Biol 2016 ;1400:33-45

Department of Human Genetics, McGill University, Montréal, QC, Canada, H3A 1A4.

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http://dx.doi.org/10.1007/978-1-4939-3372-3_3DOI Listing
December 2016

Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors.

Authors:
Jonathon Torchia Brian Golbourn Shengrui Feng King Ching Ho Patrick Sin-Chan Alexandre Vasiljevic Joseph D Norman Paul Guilhamon Livia Garzia Natalia R Agamez Mei Lu Tiffany S Chan Daniel Picard Pasqualino de Antonellis Dong-Anh Khuong-Quang Aline C Planello Constanze Zeller Dalia Barsyte-Lovejoy Lucie Lafay-Cousin Louis Letourneau Mathieu Bourgey Man Yu Deena M A Gendoo Misko Dzamba Mark Barszczyk Tiago Medina Alexandra N Riemenschneider A Sorana Morrissy Young-Shin Ra Vijay Ramaswamy Marc Remke Christopher P Dunham Stephen Yip Ho-Keung Ng Jian-Qiang Lu Vivek Mehta Steffen Albrecht Jose Pimentel Jennifer A Chan Gino R Somers Claudia C Faria Lucia Roque Maryam Fouladi Lindsey M Hoffman Andrew S Moore Yin Wang Seung Ah Choi Jordan R Hansford Daniel Catchpoole Diane K Birks Nicholas K Foreman Doug Strother Almos Klekner Laszló Bognár Miklós Garami Péter Hauser Tibor Hortobágyi Beverly Wilson Juliette Hukin Anne-Sophie Carret Timothy E Van Meter Eugene I Hwang Amar Gajjar Shih-Hwa Chiou Hideo Nakamura Helen Toledano Iris Fried Daniel Fults Takafumi Wataya Chris Fryer David D Eisenstat Katrin Scheinemann Adam J Fleming Donna L Johnston Jean Michaud Shayna Zelcer Robert Hammond Samina Afzal David A Ramsay Nongnuch Sirachainan Suradej Hongeng Noppadol Larbcharoensub Richard G Grundy Rishi R Lulla Jason R Fangusaro Harriet Druker Ute Bartels Ronald Grant David Malkin C Jane McGlade Theodore Nicolaides Tarik Tihan Joanna Phillips Jacek Majewski Alexandre Montpetit Guillaume Bourque Gary D Bader Alyssa T Reddy G Yancey Gillespie Monika Warmuth-Metz Stefan Rutkowski Uri Tabori Mathieu Lupien Michael Brudno Ulrich Schüller Torsten Pietsch Alexander R Judkins Cynthia E Hawkins Eric Bouffet Seung-Ki Kim Peter B Dirks Michael D Taylor Anat Erdreich-Epstein Cheryl H Arrowsmith Daniel D De Carvalho James T Rutka Nada Jabado Annie Huang

Cancer Cell 2016 Dec;30(6):891-908

Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5G0A4, Canada; Department of Paediatrics, University of Toronto, Toronto, ON M5G0A4, Canada; Division of Hematology/Oncology, Hospital for Sick Children, Toronto, ON M5G1X8, Canada; Arthur and Sonia Labatt Brain Tumour Research Centre, Hospital for Sick Children, Toronto, ON M5G1X8, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500911PMC
December 2016

Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells.

Cell 2016 11;167(5):1398-1414.e24

Department of Human Genetics, The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1HH, UK; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Long Road, Cambridge CB2 0PT, UK; British Heart Foundation Centre of Excellence, Division of Cardiovascular Medicine, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0QQ, UK; The National Institute for Health Research Blood and Transplant Unit (NIHR BTRU) in Donor Health and Genomics at the University of Cambridge, Strangeways Research Laboratory, University of Cambridge, Wort's Causeway, Cambridge CB1 8RN, UK. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00928674163144
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http://dx.doi.org/10.1016/j.cell.2016.10.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119954PMC
November 2016

The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.

Cell 2016 11;167(5):1415-1429.e19

Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Long Road, Cambridge CB2 0PT, UK; Department of Human Genetics, The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1HH, UK; The National Institute for Health Research Blood and Transplant Unit (NIHR BTRU) in Donor Health and Genomics at the University of Cambridge, University of Cambridge, Strangeways Research Laboratory, Wort's Causeway, Cambridge CB1 8RN, UK; British Heart Foundation Centre of Excellence, Division of Cardiovascular Medicine, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0QQ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2016.10.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300907PMC
November 2016

The International Human Epigenome Consortium Data Portal.

Cell Syst 2016 11 15;3(5):496-499.e2. Epub 2016 Nov 15.

McGill University and Génome Québec Innovation Center, Montréal, QC H3A 0G1, Canada; Department of Human Genetics, McGill University, Montréal, QC H3A 0G1, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cels.2016.10.019DOI Listing
November 2016

Evolving data access policy: The Canadian context.

Facets (Ott) 2016 Sep;1(1):138-147

Department of Human Genetics, Centre of Genomics and Policy, Faculty of Medicine, McGill University, Montreal, QC H3A 0G1, Canada.

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http://dx.doi.org/10.1139/facets-2016-0002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5158303PMC
September 2016

ABCA7 rare variants and Alzheimer disease risk.

Neurology 2016 Jun 1;86(23):2134-7. Epub 2016 Apr 1.

From INSERM (K.L.G., G.N., O.Q., C.C., D.W., S.R., A.C.R., A.R.-L., T.F., D.H., D.C.), U1079, IRIB, University of Rouen, Normandy University; Normandy Centre for Genomic Medicine and Personalized Medicine (K.L.G., G.N., O.Q., C.C., D.W., S.R., A.-C.R., A.R.-L., T.F., D.H., D.C.), Rouen; Department of Genetics (G.N., T.F., D.H.), CNR-MAJ (G.N., O.Q., C.C., D.W., S.R., A.-C.R., F.P., A.R.-S., D.H., D.C.), and Department of Neurology (D.W., D.H.), Rouen University Hospital; INSERM (C.B., B.G.-B., P.A., J.-C.L.), U1167, Lille; Institut Pasteur de Lille (C.B., B.G.-B., P.A., J.-C.L.); Université Lille-Nord de France (C.B., B.G.-B., P.A., J.-C.L.); Centre National de Génotypage (D.B., J.-G.G., R.O., A.B., V.M., J.-F.Deleuze.), Institut de Génomique, CEA, Evry; Fondation Jean Dausset (J.-F.Deleuze.), Centre d'Etudes du Polymorphisme Humain, Paris, France; McGill University and Génome Québec Innovation Centre (H.M.M., G.B., M.L.), Montréal, Canada; INSERM (R.R.), UMR 1087, l'Institut du Thorax, CHU Nantes; CNRS (R.R.), UMR 6291, Université de Nantes; INSERM (L.L., J.-F.Dartigues.), U897, Bordeaux; University of Bordeaux (L.L., J.-F.Dartigues.); Department of Neurology (F.P., A.R.S.), Lille University Hospital; INSERM (E.G.), UMR1078, CHU Brest, Université Bretagne Occidentale, Brest; and Department of Research (D.C.), Rouvray Psychiatric Hospital, Sotteville-lès-Rouen, France.

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http://dx.doi.org/10.1212/WNL.0000000000002627DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898320PMC
June 2016

The PGC-1α/ERRα Axis Represses One-Carbon Metabolism and Promotes Sensitivity to Anti-folate Therapy in Breast Cancer.

Cell Rep 2016 Feb 21;14(4):920-931. Epub 2016 Jan 21.

Goodman Cancer Research Centre, McGill University, Montréal, QC H3A 1A3, Canada; Department of Biochemistry, McGill University, Montréal, QC H3G 1Y6, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.12.086DOI Listing
February 2016

High-dose folic acid supplementation alters the human sperm methylome and is influenced by the MTHFR C677T polymorphism.

Hum Mol Genet 2015 Nov 24;24(22):6301-13. Epub 2015 Aug 24.

Department of Human Genetics, Departments of Pediatrics and Pharmacology & Therapeutics, McGill University, Montreal, QC, Canada H4A 3J1, Montreal Children's Hospital and Research Institute of the McGill University Health Centre, Montreal, QC, Canada H4A 3J1,

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http://dx.doi.org/10.1093/hmg/ddv338DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614702PMC
November 2015

A call for benchmarking transposable element annotation methods.

Mob DNA 2015 4;6:13. Epub 2015 Aug 4.

School of Computer Science, McGill University, McConnell Engineering Bldg., Rm. 318, 3480 Rue University, Montréal, Québec H3A 0E9 Canada ; McGill Centre for Bioinformatics, McGill University, Montréal, Québec Canada.

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http://dx.doi.org/10.1186/s13100-015-0044-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524446PMC
August 2015

A replication study for association of 53 single nucleotide polymorphisms in ScoliScore test with adolescent idiopathic scoliosis in French-Canadian population.

Spine (Phila Pa 1976) 2015 Apr;40(8):537-43

*Viscogliosi Laboratory in Molecular Genetics of Musculoskeletal Diseases, Sainte-Justine University Hospital Research Center, Montréal, Québec, Canada †Department of Biochemistry and Molecular Medicine, Faculty of Medicine, Université de Montréal, Montréal, Québec, Canada ‡Genome Quebec Innovation Center, McGill University, Montréal, Québec, Canada §LIS3D Laboratory, Sainte-Justine University Hospital Research Center, Montréal, Québec, Canada ¶Orthopedic Division, Sainte-Justine University Hospital and Department of Surgery, Faculty of Medicine, Université de Montréal, Montréal, Québec, Canada ‖Orthopedic Division, Montreal Children's Hospital, Department of Surgery, Faculty of Medicine, McGill University, Montréal, Québec, Canada; and **Department of Stomatology, Faculty of Dentistry, Université de Montréal, Montréal, Québec, Canada.

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http://dx.doi.org/10.1097/BRS.0000000000000807DOI Listing
April 2015

Transient DNMT1 suppression reveals hidden heritable marks in the genome.

Nucleic Acids Res 2015 Feb 10;43(3):1485-97. Epub 2015 Jan 10.

Departments of Pediatrics, Human Genetics and Pharmacology & Therapeutics, McGill University and the Research Institute of the McGill University Health Centre at the Montreal Children's Hospital, Montreal, QC H3Z 2Z3, Canada

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http://dx.doi.org/10.1093/nar/gku1386DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330356PMC
February 2015

Molecular convergence of neurodevelopmental disorders.

Am J Hum Genet 2014 Nov 9;95(5):490-508. Epub 2014 Oct 9.

Department of Psychiatry, McGill University, Montreal, QC H4H 1R3, Canada; McGill Group for Suicide Studies, Douglas Hospital Research Institute, Montreal, QC H4H 1R3, Canada; Department of Human Genetics, McGill University, Montreal, QC H4H 1R3, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2014.09.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225591PMC
November 2014

Mobile genetic elements and genome evolution 2014.

Mob DNA 2014 18;5:26. Epub 2014 Nov 18.

Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD USA.

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http://dx.doi.org/10.1186/1759-8753-5-26DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363357PMC
November 2014

Variation in genomic landscape of clear cell renal cell carcinoma across Europe.

Nat Commun 2014 Oct 29;5:5135. Epub 2014 Oct 29.

1] Department of Human Genetics, McGill University, 1205 Dr Penfield Avenue, Montreal, Quebec, Canada H3A 1B1 [2] Fondation Jean Dausset - Centre d'Etude du Polymorphisme Humain, 27 rue Juliette Dodu, 75010 Paris, France [3] Centre National de Génotypage, CEA - Institute de Génomique, 2 rue Gaston Crémieux, 91000 Evry, France.

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http://dx.doi.org/10.1038/ncomms6135DOI Listing
October 2014

The retrovirus HERVH is a long noncoding RNA required for human embryonic stem cell identity.

Nat Struct Mol Biol 2014 Apr 30;21(4):423-5. Epub 2014 Mar 30.

1] Gene Regulation Laboratory, Genome Institute of Singapore, Singapore. [2] Department of Biochemistry, National University of Singapore, Singapore. [3] Department of Biological Sciences, National University of Singapore, Singapore. [4] School of Biological Sciences, Nanyang Technological University, Singapore.

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http://dx.doi.org/10.1038/nsmb.2799DOI Listing
April 2014

Tissue factor expression provokes escape from tumor dormancy and leads to genomic alterations.

Proc Natl Acad Sci U S A 2014 Mar 11;111(9):3544-9. Epub 2014 Feb 11.

Montreal Children's Hospital, Research Institute of McGill University Health Centre, McGill University, Montreal, QC, Canada H3Z 2Z3.

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http://dx.doi.org/10.1073/pnas.1314118111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948265PMC
March 2014

SON connects the splicing-regulatory network with pluripotency in human embryonic stem cells.

Nat Cell Biol 2013 Oct 8;15(10):1141-1152. Epub 2013 Sep 8.

Gene Regulation Laboratory, Genome Institute of Singapore, 138672, Singapore.

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http://dx.doi.org/10.1038/ncb2839DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097007PMC
October 2013

The majority of primate-specific regulatory sequences are derived from transposable elements.

PLoS Genet 2013 May 9;9(5):e1003504. Epub 2013 May 9.

Computational and Systems Biology, Genome Institute of Singapore, Singapore, Singapore.

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http://dx.doi.org/10.1371/journal.pgen.1003504DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649963PMC
May 2013

Molecular and genetic crosstalks between mTOR and ERRα are key determinants of rapamycin-induced nonalcoholic fatty liver.

Cell Metab 2013 Apr;17(4):586-98

Rosalind and Morris Goodman Cancer Research Centre, McGill University, 1160 Pine Avenue West, Montréal, QC H3A 1A3, Canada.

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http://dx.doi.org/10.1016/j.cmet.2013.03.003DOI Listing
April 2013

Transposable elements are major contributors to the origin, diversification, and regulation of vertebrate long noncoding RNAs.

PLoS Genet 2013 Apr 25;9(4):e1003470. Epub 2013 Apr 25.

Department of Human Genetics, University of Utah School of Medicine, Salt Lake City, Utah, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1003470DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636048PMC
April 2013

CpG deamination creates transcription factor-binding sites with high efficiency.

Genome Biol Evol 2011 19;3:1304-11. Epub 2011 Oct 19.

Department of Computational Molecular Biology, Max Planck Institute for Molecular Genetics, Berlin, Germany.

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http://dx.doi.org/10.1093/gbe/evr107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228489PMC
March 2012

Conserved and non-conserved enhancers direct tissue specific transcription in ancient germ layer specific developmental control genes.

BMC Dev Biol 2011 Oct 20;11:63. Epub 2011 Oct 20.

Stem Cell and Developmental Biology, Genome Institute of Singapore, 60 Biopolis Street, 138672, Singapore.

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http://bmcdevbiol.biomedcentral.com/articles/10.1186/1471-21
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http://dx.doi.org/10.1186/1471-213X-11-63DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210094PMC
October 2011

In silico tandem affinity purification refines an Oct4 interaction list.

Stem Cell Res Ther 2011 May 13;2(3):26. Epub 2011 May 13.

Stem Cell and Developmental Biology Group, Genome Institute of Singapore, 60 Biopolis Street, 138672, Singapore.

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http://dx.doi.org/10.1186/scrt67DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218817PMC
May 2011

Transposable elements have rewired the core regulatory network of human embryonic stem cells.

Nat Genet 2010 Jul 6;42(7):631-4. Epub 2010 Jun 6.

Computational and Mathematical Biology, Genome Institute of Singapore, Singapore, Singapore.

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http://dx.doi.org/10.1038/ng.600DOI Listing
July 2010

webMGR: an online tool for the multiple genome rearrangement problem.

Bioinformatics 2010 Feb 18;26(3):408-10. Epub 2009 Dec 18.

Genome Institute of Singapore, 60 Biopolis Street, #02-01, Genome, Singapore 138672.

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http://bioinformatics.oxfordjournals.org/content/early/2009/
Web Search
http://bioinformatics.oxfordjournals.org/cgi/doi/10.1093/bio
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http://dx.doi.org/10.1093/bioinformatics/btp689DOI Listing
February 2010

Transposable elements in gene regulation and in the evolution of vertebrate genomes.

Curr Opin Genet Dev 2009 Dec 13;19(6):607-12. Epub 2009 Nov 13.

Genome Institute of Singapore, Singapore 138672, Singapore.

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http://dx.doi.org/10.1016/j.gde.2009.10.013DOI Listing
December 2009

Recovering genome rearrangements in the mammalian phylogeny.

Genome Res 2009 May;19(5):934-42

Computational and Mathematical Biology, Genome Institute of Singapore, Singapore.

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http://dx.doi.org/10.1101/gr.086009.108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2675982PMC
May 2009

Evolution of the mammalian transcription factor binding repertoire via transposable elements.

Genome Res 2008 Nov 5;18(11):1752-62. Epub 2008 Aug 5.

Computational and Mathematical Biology, Genome Institute of Singapore, Singapore 138672, Singapore.

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http://dx.doi.org/10.1101/gr.080663.108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577865PMC
November 2008

Regulation of estrogen receptor-mediated long range transcription via evolutionarily conserved distal response elements.

J Biol Chem 2008 Nov 25;283(47):32977-88. Epub 2008 Aug 25.

Cancer Biology and Pharmacology, Genome Institute of Singapore, Agency for Science, Technology and Research, 60 Biopolis St., 02-01 Genome, Singapore 138672.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M802024200
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http://dx.doi.org/10.1074/jbc.M802024200DOI Listing
November 2008

Computational tools for the analysis of rearrangements in mammalian genomes.

Methods Mol Biol 2008 ;422:145-70

Department of Mathematics, University of California-San Diego, La Jolla, CA.

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http://dx.doi.org/10.1007/978-1-59745-581-7_10DOI Listing
August 2008

Computational tools for the analysis of rearrangements in mammalian genomes.

Methods Mol Biol 2008 ;452:431-55

Genome Institute of Singapore, Singapore, Republic of Singapore.

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http://dx.doi.org/10.1007/978-1-60327-159-2_20DOI Listing
July 2008

The convergence of cytogenetics and rearrangement-based models for ancestral genome reconstruction.

Genome Res 2006 Mar;16(3):311-3

Information and Mathematical Sciences, Genome Institute of Singapore, 138672 Singapore.

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http://dx.doi.org/10.1101/gr.4631806DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1415205PMC
March 2006

A population-based LD map of the human chromosome 6p.

Immunogenetics 2005 Sep 29;57(8):559-65. Epub 2005 Sep 29.

WHO Collaborating Center for Immunology, Faculty of Medicine, National University of Singapore.

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http://dx.doi.org/10.1007/s00251-005-0002-4DOI Listing
September 2005

Improving gene network inference by comparing expression time-series across species, developmental stages or tissues.

J Bioinform Comput Biol 2004 Dec;2(4):765-83

Centre de Recherches Mathématiques, Université de Montréal, Montréal, Québec, H3C 3J7, Canada.

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http://dx.doi.org/10.1142/s0219720004000892DOI Listing
December 2004

Reconstructing the genomic architecture of ancestral mammals: lessons from human, mouse, and rat genomes.

Genome Res 2004 Apr;14(4):507-16

Centre de Recherches Mathématiques, Université de Montréal, Canada H3C 3J7.

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http://dx.doi.org/10.1101/gr.1975204DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC383294PMC
April 2004

Reconstructing the genomic architecture of mammalian ancestors using multispecies comparative maps.

Hum Genomics 2003 Nov;1(1):30-40

Laboratory of Genomic Diversity, National Cancer Institute, Frederick, MD 21702, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525001PMC
http://dx.doi.org/10.1186/1479-7364-1-1-30DOI Listing
November 2003