Guifang Jia

Guifang Jia

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Guifang Jia

Publications by authors named "Guifang Jia"

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36Publications

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N6-methyldeoxyadenine is a transgenerational epigenetic signal for mitochondrial stress adaptation.

Nat Cell Biol 2019 03 3;21(3):319-327. Epub 2018 Dec 3.

State Key Laboratory of Membrane Biology, Institute of Molecular Medicine, Beijing Key Laboratory of Cardiometabolic Molecular Medicine and Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, China.

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http://dx.doi.org/10.1038/s41556-018-0238-5DOI Listing
March 2019

Structural insights into FTO's catalytic mechanism for the demethylation of multiple RNA substrates.

Proc Natl Acad Sci U S A 2019 02 4;116(8):2919-2924. Epub 2019 Feb 4.

Synthetic and Functional Biomolecules Center, Beijing National Laboratory for Molecular Sciences, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China;

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http://dx.doi.org/10.1073/pnas.1820574116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386707PMC
February 2019

Dynamic and reversible RNA N -methyladenosine methylation.

Wiley Interdiscip Rev RNA 2019 01 25;10(1):e1507. Epub 2018 Sep 25.

Synthetic and Functional Biomolecules Center, Beijing National Laboratory for Molecular Sciences, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, Department of Chemical Biology, College of Chemistry and Molecular Engineering, Peking University, Beijing, China.

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http://dx.doi.org/10.1002/wrna.1507DOI Listing
January 2019

An Elongation- and Ligation-Based qPCR Amplification Method for the Radiolabeling-Free Detection of Locus-Specific N -Methyladenosine Modification.

Angew Chem Int Ed Engl 2018 12 8;57(49):15995-16000. Epub 2018 Nov 8.

Department of Chemical Biology, Synthetic and Functional Biomolecules Center, Beijing National Laboratory for Molecular Sciences, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Molecular Engineering, Beijing Advanced Innovation Center for Genomics, Peking University, Beijing, 100871, China.

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http://doi.wiley.com/10.1002/anie.201807942
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http://dx.doi.org/10.1002/anie.201807942DOI Listing
December 2018

Differential mA, mA, and mA Demethylation Mediated by FTO in the Cell Nucleus and Cytoplasm.

Mol Cell 2018 09 6;71(6):973-985.e5. Epub 2018 Sep 6.

Department of Chemistry, Department of Biochemistry and Molecular Biology, and Institute for Biophysical Dynamics, The University of Chicago, 929 East 57 Street, Chicago, IL 60637, USA; Howard Hughes Medical Institute, The University of Chicago, 929 East 57 Street, Chicago, IL 60637, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10972765183064
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http://dx.doi.org/10.1016/j.molcel.2018.08.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151148PMC
September 2018

Designing fluorescent biosensors using circular permutations of riboswitches.

Methods 2018 07 16;143:102-109. Epub 2018 Feb 16.

Department of Chemistry, University of California, Berkeley 94720, USA; Department of Molecular & Cell Biology, University of California, Berkeley 94720, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ymeth.2018.02.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051913PMC
July 2018

Reversible RNA Modification N-methyladenosine (mA) in mRNA and tRNA.

Genomics Proteomics Bioinformatics 2018 06 14;16(3):155-161. Epub 2018 Jun 14.

Synthetic and Functional Biomolecules Center, Beijing National Laboratory for Molecular Sciences, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China. Electronic address:

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http://dx.doi.org/10.1016/j.gpb.2018.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076376PMC
June 2018

The mA Reader ECT2 Controls Trichome Morphology by Affecting mRNA Stability in Arabidopsis.

Plant Cell 2018 05 30;30(5):968-985. Epub 2018 Apr 30.

Synthetic and Functional Biomolecules Center, Beijing National Laboratory for Molecular Sciences, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China

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http://dx.doi.org/10.1105/tpc.17.00934DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002187PMC
May 2018

ALKBH10B Is an RNA -Methyladenosine Demethylase Affecting Arabidopsis Floral Transition.

Plant Cell 2017 12 27;29(12):2995-3011. Epub 2017 Nov 27.

Synthetic and Functional Biomolecules Center, Beijing National Laboratory for Molecular Sciences, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China

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http://dx.doi.org/10.1105/tpc.16.00912DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757257PMC
December 2017

Mettl3-/Mettl14-mediated mRNA N-methyladenosine modulates murine spermatogenesis.

Cell Res 2017 Oct 15;27(10):1216-1230. Epub 2017 Sep 15.

State Key Laboratory of Molecular Biology Shanghai Key Laboratory of Molecular Andrology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China.

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http://www.nature.com/doifinder/10.1038/cr.2017.117
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http://dx.doi.org/10.1038/cr.2017.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630681PMC
October 2017

New Edges of RNA Adenosine Methylation Modifications.

Authors:
Ye Wang Guifang Jia

Genomics Proteomics Bioinformatics 2016 06 30;14(3):172-175. Epub 2016 May 30.

Synthetic and Functional Biomolecules Center, Beijing National Laboratory for Molecular Sciences, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China. Electronic address:

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http://dx.doi.org/10.1016/j.gpb.2016.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936603PMC
June 2016

Unique features of the m6A methylome in Arabidopsis thaliana.

Nat Commun 2014 Nov 28;5:5630. Epub 2014 Nov 28.

Department of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, 929 East 57th Street, Chicago, Illinois 60637, USA.

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http://dx.doi.org/10.1038/ncomms6630DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248235PMC
November 2014

A METTL3-METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation.

Nat Chem Biol 2014 Feb 6;10(2):93-5. Epub 2013 Dec 6.

1] Department of Chemistry, University of Chicago, Chicago, Illinois, USA. [2] Institute for Biophysical Dynamics, University of Chicago, Chicago, Illinois, USA.

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http://dx.doi.org/10.1038/nchembio.1432DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3911877PMC
February 2014

N6-methyladenosine-dependent regulation of messenger RNA stability.

Nature 2014 Jan 27;505(7481):117-20. Epub 2013 Nov 27.

Department of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, 929 East 57th Street, Chicago, Illinois 60637, USA.

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http://dx.doi.org/10.1038/nature12730DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877715PMC
January 2014

Methylation modifications in eukaryotic messenger RNA.

Authors:
Jun Liu Guifang Jia

J Genet Genomics 2014 Jan 9;41(1):21-33. Epub 2013 Nov 9.

Synthetic and Functional Biomolecules Center, Beijing National Laboratory for Molecular Sciences, Department of Chemical Biology, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China. Electronic address:

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http://dx.doi.org/10.1016/j.jgg.2013.10.002DOI Listing
January 2014

FTO-mediated formation of N6-hydroxymethyladenosine and N6-formyladenosine in mammalian RNA.

Nat Commun 2013 ;4:1798

Department of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, 929 East 57th Street, Chicago, Illinois 60637, USA.

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http://dx.doi.org/10.1038/ncomms2822DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658177PMC
November 2013

Reversible RNA adenosine methylation in biological regulation.

Trends Genet 2013 Feb 4;29(2):108-15. Epub 2012 Dec 4.

Department of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, 929 East 57th Street, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1016/j.tig.2012.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558665PMC
February 2013

Development of cell-active N6-methyladenosine RNA demethylase FTO inhibitor.

J Am Chem Soc 2012 Oct 17;134(43):17963-71. Epub 2012 Oct 17.

State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.

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http://dx.doi.org/10.1021/ja3064149DOI Listing
October 2012

Duplex interrogation by a direct DNA repair protein in search of base damage.

Nat Struct Mol Biol 2012 Jun 3;19(7):671-6. Epub 2012 Jun 3.

State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing, China.

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http://www.nature.com/articles/nsmb.2320
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http://dx.doi.org/10.1038/nsmb.2320DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392526PMC
June 2012

N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO.

Nat Chem Biol 2011 Oct 16;7(12):885-7. Epub 2011 Oct 16.

Department of Chemistry, University of Chicago, Chicago, Illinois, USA.

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http://dx.doi.org/10.1038/nchembio.687DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218240PMC
October 2011

Iron-catalysed oxidation intermediates captured in a DNA repair dioxygenase.

Nature 2010 Nov;468(7321):330-3

Department of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, 929 East 57th Street, Chicago, Illinois 60637, USA.

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http://dx.doi.org/10.1038/nature09497DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058853PMC
November 2010

Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO.

FEBS Lett 2008 Oct 5;582(23-24):3313-9. Epub 2008 Sep 5.

Department of Chemistry, The University of Chicago, 929 East 57th Street, Chicago, IL 60637, USA.

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http://doi.wiley.com/10.1016/j.febslet.2008.08.019
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http://dx.doi.org/10.1016/j.febslet.2008.08.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577709PMC
October 2008

Stereoselective toxicokinetics and tissue distribution of ethofumesate in rabbits.

Chirality 2007 Aug;19(8):632-7

Department of Applied Chemistry, China Agricultural University, Beijing, People's Republic of China.

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http://dx.doi.org/10.1002/chir.20428DOI Listing
August 2007

Determination of carbaryl and its metabolite 1-naphthol in water samples by fluorescence spectrophotometer after anionic surfactant micelle-mediated extraction with sodium dodecylsulfate.

Spectrochim Acta A Mol Biomol Spectrosc 2007 Jun 12;67(2):460-4. Epub 2006 Aug 12.

Department of Applied Chemistry, China Agricultural University, Beijing 100094, China.

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http://dx.doi.org/10.1016/j.saa.2006.08.003DOI Listing
June 2007

Stereoselective degradation of fungicide benalaxyl in soils and cucumber plants.

Chirality 2007 May;19(4):300-6

Department of Applied Chemistry, China Agricultural University, Beijing 100094, China.

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http://dx.doi.org/10.1002/chir.20381DOI Listing
May 2007

Stereoselective degradation kinetics of tebuconazole in rabbits.

Chirality 2007 Feb;19(2):141-7

Department of Applied Chemistry, China Agricultural University, Beijing, China.

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http://dx.doi.org/10.1002/chir.20340DOI Listing
February 2007

Enantiomeric resolution of new triazole compounds by high-performance liquid chromatography.

J Sep Sci 2007 Feb;30(3):344-51

Department of Applied Chemistry, China Agricultural University, Beijing, China.

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http://dx.doi.org/10.1002/jssc.200600282DOI Listing
February 2007

Determination of Etofenprox in environmental samples by HPLC after anionic surfactant micelle-mediated extraction (coacervation extraction).

Anal Bioanal Chem 2006 Mar 21;384(6):1423-7. Epub 2006 Feb 21.

Department of Applied Chemistry, China Agricultural University, Beijing, 100094, People's Republic of China.

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http://dx.doi.org/10.1007/s00216-005-0273-5DOI Listing
March 2006

Stereoselective degradation kinetics of theta-cypermethrin in rats.

Environ Sci Technol 2006 Feb;40(3):721-6

Department of Applied Chemistry, China Agricultural University, Beijing 100094, China.

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http://dx.doi.org/10.1021/es052025+DOI Listing
February 2006

Effect of alcohols and temperature on the direct chiral resolutions of fipronil, isocarbophos and carfentrazone-ethyl.

Biomed Chromatogr 2005 Jul;19(6):454-8

Department of Applied Chemistry, China Agricultural University, Beijing 100094, People's Republic of China.

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http://dx.doi.org/10.1002/bmc.505DOI Listing
July 2005

Determination of deoxyribonucleic acids by a resonance light scattering technique and its application.

Spectrochim Acta A Mol Biomol Spectrosc 2003 Dec;59(14):3295-301

College of Applied Chemistry, China Agricultural University, Beijing 100094, China.

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http://dx.doi.org/10.1016/s1386-1425(03)00155-0DOI Listing
December 2003