Publications by authors named "Guido Kroemer"

100Publications

Immunostimulation with chemotherapy in the era of immune checkpoint inhibitors.

Nat Rev Clin Oncol 2020 Aug 5. Epub 2020 Aug 5.

Université de Paris, Paris, France.

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http://dx.doi.org/10.1038/s41571-020-0413-zDOI Listing
August 2020

Calreticulin and cancer.

Cell Res 2020 Jul 30. Epub 2020 Jul 30.

Department of Radiation Oncology, Weill Cornell Medical College, New York, NY, USA.

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http://dx.doi.org/10.1038/s41422-020-0383-9DOI Listing
July 2020

Extending the mode of action of triethylenetetramine (trientine): Autophagy besides copper chelation.

J Hepatol 2020 Jul 16. Epub 2020 Jul 16.

Centre de Recherche des Cordeliers, INSERM U1138, Team "Metabolism, Cancer & Immunity", Sorbonne Université, Université de Paris, Paris, France; Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Campus, Villejuif, France; Pôle de Biologie, Hôpital Européen Georges Pompidou, AP-HP, Paris, France; Suzhou Institute for Systems Medicine, Chinese Academy of Medical Sciences, Suzhou, China; Department of Women's and Children's Health, Karolinska Institute, Karolinska University Hospital, Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2020.05.046DOI Listing
July 2020

Nutritional Aspects of Spermidine.

Annu Rev Nutr 2020 Jul 7. Epub 2020 Jul 7.

Equipe Labellisée par la Ligue Contre le Cancer, Université de Paris, Sorbonne Université, INSERM U1138, Centre de Recherche des Cordeliers, 75006 Paris, France; email:

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http://dx.doi.org/10.1146/annurev-nutr-120419-015419DOI Listing
July 2020

Triethylenetetramine (trientine): a caloric restriction mimetic with a new mode of action.

Autophagy 2020 Aug 16;16(8):1534-1536. Epub 2020 Jun 16.

Centre de Recherche des Cordeliers, INSERM U1138, Team "Metabolism, Cancer & Immunity", Sorbonne Université, Université de Paris , Paris, France.

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http://dx.doi.org/10.1080/15548627.2020.1778293DOI Listing
August 2020

Phosphorylation of eukaryotic initiation factor-2α (eIF2α) in autophagy.

Cell Death Dis 2020 Jun 8;11(6):433. Epub 2020 Jun 8.

Equipe Labellisée par la Ligue Contre le Cancer, Université de Paris, Sorbonne Université, INSERM UMR1138, Centre de Recherche des Cordeliers, Paris, France.

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http://dx.doi.org/10.1038/s41419-020-2642-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280501PMC
June 2020

Seeking Cellular Fitness and Immune Evasion: Autophagy in Pancreatic Carcinoma.

Cancer Cell 2020 Jun 28;37(6):759-760. Epub 2020 May 28.

Suzhou Institute for Systems Medicine, Chinese Academy of Medical Sciences, Suzhou, China; Faculty of Medicine, Université Paris Saclay, Le Kremlin-Bicêtre, France; Gustave Roussy Comprehensive Cancer Institute, Villejuif, France; INSERM U1015, Villejuif, France; Center of Clinical Investigations in Biotherapies of Cancer (CICBT) 1428, Villejuif, France. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2020.05.009DOI Listing
June 2020

Copper - a novel stimulator of autophagy.

Cell Stress 2020 Apr 24;4(5):92-94. Epub 2020 Apr 24.

Centre de Recherche des Cordeliers, Equipe labellisée par la Ligue contre le cancer, Université de Paris, Sorbonne Université, Inserm U1138, Institut Universitaire de France, Paris, France.

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http://dx.doi.org/10.15698/cst2020.05.218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212532PMC
April 2020

Bacterial infection and non-Hodgkin's lymphoma.

Crit Rev Microbiol 2020 May 15;46(3):270-287. Epub 2020 May 15.

Aix-Marseille University, IRD, APHM, MEPHI, Marseille, France.

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http://dx.doi.org/10.1080/1040841X.2020.1760786DOI Listing
May 2020

CD4 T Cells at the Center of Inflammaging.

Cell Metab 2020 Jul 12;32(1):4-5. Epub 2020 May 12.

Suzhou Institute for Systems Medicine, Chinese Academy of Medical Sciences, Suzhou, China; Faculty of Medicine, Université Paris Saclay, Le Kremlin-Bicêtre, France; Gustave Roussy Comprehensive Cancer Institute, Villejuif, France; INSERM U1015, Villejuif, France; Center of Clinical Investigations in Biotherapies of Cancer (CICBT) 1428, Villejuif, France.

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http://dx.doi.org/10.1016/j.cmet.2020.04.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217078PMC
July 2020

Digesting the crisis: autophagy and coronaviruses.

Microb Cell 2020 May 4;7(5):119-128. Epub 2020 May 4.

Institute for Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria.

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http://dx.doi.org/10.15698/mic2020.05.715DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199282PMC
May 2020

The ambiguous role of FPR1 in immunity and inflammation.

Oncoimmunology 2020 30;9(1):1760061. Epub 2020 Apr 30.

Equipe labellisée par la Ligue contre le cancer, Université de Paris, Sorbonne Université, INSERM U1138, Centre de Recherche des Cordeliers, Paris, France.

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http://dx.doi.org/10.1080/2162402X.2020.1760061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199809PMC
April 2020

Possible mechanisms of cancer prevention by nicotinamide.

Br J Pharmacol 2020 May 7. Epub 2020 May 7.

Department of Radiation Oncology, Weill Cornell Medical College, New York, NY, USA.

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http://dx.doi.org/10.1111/bph.15096DOI Listing
May 2020

Gut Bacteria Composition Drives Primary Resistance to Cancer Immunotherapy in Renal Cell Carcinoma Patients.

Eur Urol 2020 Aug 4;78(2):195-206. Epub 2020 May 4.

Gustave Roussy Cancer Campus (GRCC), Villejuif, France; Institut National de la Santé et de la Recherche Médicale (INSERM) U1015, Équipe Labellisée-Ligue Nationale contre le Cancer, Villejuif, France; Faculté de Médecine Kremlin-Bicêtre, Université Paris Sud, Université Paris Saclay, France; Department of Medical Oncology, Gustave Roussy Cancer Campus (GRCC), Villejuif, France; Center of Clinical Investigations in Biotherapies of Cancer (CICBT) 1428, Villejuif, France; EverImmune, GRCC, Villejuif, France; Suzhou Institute for Systems Medicine, Chinese Academy of Medical Sciences, Suzhou, China. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2020.04.044DOI Listing
August 2020

Myeloid PTEN promotes chemotherapy-induced NLRP3-inflammasome activation and antitumour immunity.

Nat Cell Biol 2020 Jun 4;22(6):716-727. Epub 2020 May 4.

Hefei National Laboratory for Physical Sciences at Microscale, the CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Basic Medical Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.

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http://dx.doi.org/10.1038/s41556-020-0510-3DOI Listing
June 2020

FLT3LG - a biomarker reflecting clinical responses to the immunogenic cell death inducer oxaliplatin.

Oncoimmunology 2020 21;9(1):1755214. Epub 2020 Apr 21.

Gustave Roussy Comprehensive Cancer Institute, Villejuif, France.

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http://dx.doi.org/10.1080/2162402X.2020.1755214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185211PMC
April 2020

Autophagy induction by thiostrepton for the improvement of anticancer therapy.

Autophagy 2020 06 24;16(6):1166-1167. Epub 2020 Apr 24.

Equipe Labellisée Par La Ligue Contre Le Cancer, Université De Paris, Sorbonne Université , Paris, France.

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http://dx.doi.org/10.1080/15548627.2020.1758417DOI Listing
June 2020

Inhibition of transcription by dactinomycin reveals a new characteristic of immunogenic cell stress.

EMBO Mol Med 2020 May 23;12(5):e11622. Epub 2020 Apr 23.

Equipe labellisée par la Ligue contre le Cancer, Sorbonne Université, INSERM UMR1138, Centre de Recherche des Cordeliers, Université de Paris, Paris, France.

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http://dx.doi.org/10.15252/emmm.201911622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7207166PMC
May 2020

Noncanonical Cell Fate Regulation by Bcl-2 Proteins.

Trends Cell Biol 2020 Jul 16;30(7):537-555. Epub 2020 Apr 16.

Université de Paris, Paris, France; Department of Physiology, YLL School of Medicine and NUS Graduate School for Integrative Sciences and Engineering, National University of Singapore, Singapore; National University Cancer Institute, National University Health System, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.tcb.2020.03.004DOI Listing
July 2020

Transient Autophagy Inhibition Precipitates Oncogenesis: A Red Flag For Pharmacological Autophagy Inhibitors?

Trends Cell Biol 2020 May 27;30(5):339-340. Epub 2020 Feb 27.

Université de Paris, Paris, France; Equipe Labellisée par la Ligue contre le Cancer, INSERM U1138, Centre de Recherche des Cordeliers, Paris, France; Metabolomics and Cell Biology Platforms, Gustave Roussy Comprehensive Cancer Institute, Villejuif, France; Pôle de Biologie, Hôpital Européen Georges Pompidou, AP-HP, Paris, France; Suzhou Institute for Systems Medicine, Chinese Academy of Sciences, Suzhou, China; Department of Women's and Children's Health, Karolinska University Hospital, Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.tcb.2020.02.004DOI Listing
May 2020

Coronavirus infections: Epidemiological, clinical and immunological features and hypotheses.

Cell Stress 2020 Mar 2;4(4):66-75. Epub 2020 Mar 2.

Centre de Recherche des Cordeliers, Equipe labellisée par la Ligue contre le cancer, Université de Paris, Sorbonne Université, INSERM U1138, Institut Universitaire de France, Paris, France.

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http://dx.doi.org/10.15698/cst2020.04.216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146059PMC
March 2020

Mitophagy: An Emerging Role in Aging and Age-Associated Diseases.

Front Cell Dev Biol 2020 26;8:200. Epub 2020 Mar 26.

Gustave Roussy Cancer Campus, Villejuif, France.

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http://dx.doi.org/10.3389/fcell.2020.00200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113588PMC
March 2020

Immunogenicity of cell death driven by immune effectors.

J Immunother Cancer 2020 Apr;8(1)

Université de Paris, Paris, France

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http://dx.doi.org/10.1136/jitc-2020-000802DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7174067PMC
April 2020

The scent of death: a metabolic goodbye signal emitted by dying cells.

Cell Death Differ 2020 Jun 6;27(6):2030-2032. Epub 2020 Apr 6.

Department of Bioscience and Nutrition, Karolinska Institute, Huddinge, Sweden.

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http://dx.doi.org/10.1038/s41418-020-0533-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244487PMC
June 2020

Autophagy-Dependent Ferroptosis: Machinery and Regulation.

Cell Chem Biol 2020 Apr 10;27(4):420-435. Epub 2020 Mar 10.

The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong 510600, China; Department of Surgery, UT Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chembiol.2020.02.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7166192PMC
April 2020

Antibody-mediated neutralization of ACBP/DBI has anorexigenic and lipolytic effects.

Adipocyte 2020 12;9(1):116-119

Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Campus, Villejuif, France.

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http://dx.doi.org/10.1080/21623945.2020.1736734DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153538PMC
December 2020

TMEM173 Drives Lethal Coagulation in Sepsis.

Cell Host Microbe 2020 04 5;27(4):556-570.e6. Epub 2020 Mar 5.

The Third Affiliated Hospital, Protein Modification and Degradation Lab of Guangzhou and Guangdong, Guangzhou Medical University, Guang Zhou, Guangdong 510600, China; Department of Surgery, UT Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2020.02.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316085PMC
April 2020

Endoplasmic reticulum stress in the cellular release of damage-associated molecular patterns.

Int Rev Cell Mol Biol 2020 4;350:1-28. Epub 2019 Dec 4.

Metabolomics and Cell Biology Platforms, Gustave Roussy Comprehensive Cancer Institute, Villejuif, France; Equipe 11 labellisée Ligue contre le Cancer, Centre de Recherche des Cordeliers, INSERM, Paris, France; Université Paris Descartes, Sorbonne Paris Cité, Paris, France; Université Pierre et Marie Curie, Paris, France; Faculty of Medicine, University of Paris Sud, Kremlin-Bicêtre, France; Service anesthésie-réanimation, Hôpital Européen Georges Pompidou, AP-HP, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/bs.ircmb.2019.11.006DOI Listing
December 2019

A novel platinum-based chemotherapeutic inducing immunogenic cell death.

Oncoimmunology 2020 15;9(1):1729022. Epub 2020 Feb 15.

Equipe Labellisée Par La Ligue Contre Le Cancer, Centre De Recherche Des Cordeliers, Université De Paris, Sorbonne Université, Paris, France.

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http://dx.doi.org/10.1080/2162402X.2020.1729022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028333PMC
February 2020

ACBP is an appetite stimulator across phylogenetic barriers.

Cell Stress 2020 Jan 20;4(2):27-29. Epub 2020 Jan 20.

Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Campus, Villejuif, France.

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http://dx.doi.org/10.15698/cst2020.02.211DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997948PMC
January 2020

Secreted calreticulin mutants subvert anticancer immunosurveillance.

Oncoimmunology 2020 28;9(1):1708126. Epub 2019 Dec 28.

Equipe 11 labellisée par la Ligue contre le Cancer, Centre de Recherche des Cordeliers, Paris, France.

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http://dx.doi.org/10.1080/2162402X.2019.1708126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959454PMC
December 2019

Trial watch: chemotherapy-induced immunogenic cell death in immuno-oncology.

Oncoimmunology 2020 9;9(1):1703449. Epub 2020 Jan 9.

Cell Death Research & Therapy (CDRT) unit, Department of Cellular & Molecular Medicine, KU Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1080/2162402X.2019.1703449DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959434PMC
January 2020

Endogenous and exogenous glucocorticoids abolish the efficacy of immune-dependent cancer therapies.

Oncoimmunology 2020 11;9(1):1673635. Epub 2019 Oct 11.

Center for Systems Medicine, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.

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http://dx.doi.org/10.1080/2162402X.2019.1673635DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959448PMC
October 2019

Overexpression of apoptosis inducing factor aggravates hypoxic-ischemic brain injury in neonatal mice.

Cell Death Dis 2020 01 30;11(1):77. Epub 2020 Jan 30.

Henan Key Laboratory of Child Brain Injury, Institute of Neuroscience and Third Affiliated Hospital, Zhengzhou University, Zhengzhou, 450052, China.

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http://dx.doi.org/10.1038/s41419-020-2280-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992638PMC
January 2020

Quantitative determination of phagocytosis by bone marrow-derived dendritic cells via imaging flow cytometry.

Methods Enzymol 2020 2;632:27-37. Epub 2019 Aug 2.

Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Campus, Villejuif, France; INSERM, U1138, Paris, France; Equipe 11 labellisée par la Ligue Nationale contre le Cancer, Centre de Recherche des Cordeliers, Paris, France; Université Paris Descartes/Paris V, Sorbonne Paris Cité, Paris, France; Université Pierre et Marie Curie/Paris VI, Paris, France; Faculté de Medicine, Université Paris Saclay/Paris XI, Le Kremlin-Bicêtre, France; Suzhou Institute for Systems Medicine, Chinese Academy of Medical Sciences, Suzhou, China; Pôle de Biologie, Hôpital Européen Georges Pompidou, AP-HP, Paris, France; Department of Women's and Children's Health, Karolinska University Hospital, Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/bs.mie.2019.07.021DOI Listing
August 2019

Side-by-side comparison of flow cytometry and immunohistochemistry for detection of calreticulin exposure in the course of immunogenic cell death.

Methods Enzymol 2020 8;632:15-25. Epub 2019 Jul 8.

Department of Immunology, Charles University, 2nd Faculty of Medicine and University Hospital Motol, Prague, Czech Republic; Sotio, Prague, Czech Republic. Electronic address:

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http://dx.doi.org/10.1016/bs.mie.2019.05.025DOI Listing
July 2019

Quantitation of calreticulin exposure associated with immunogenic cell death.

Methods Enzymol 2020 3;632:1-13. Epub 2019 Jun 3.

Cell Biology and Metabolomics Platforms, Gustave Roussy Cancer Campus, Villejuif, France; Equipe 11 labellisée Ligue Nationale contre le Cancer, Centre de Recherche des Cordeliers, Paris, France; Institut National de la Santé et de la Recherche Médicale (INSERM), UMR1138, Equipe labellisée Ligue Nationale Contre le Cancer, Paris, France; Université Paris Descartes, Sorbonne Paris Cité, Paris, France; Université Pierre et Marie Curie, Paris, France; Suzhou Institute for Systems Medicine, Chinese Academy of Medical Sciences, Suzhou, China; Pôle de Biologie, Hôpital Européen Georges Pompidou, AP-HP, Paris, France; Department of Women's and Children's Health, Karolinska University Hospital, Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/bs.mie.2019.05.011DOI Listing
June 2019

Autophagy-dependent ferroptosis drives tumor-associated macrophage polarization via release and uptake of oncogenic KRAS protein.

Autophagy 2020 Jan 16:1-15. Epub 2020 Jan 16.

The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China.

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http://dx.doi.org/10.1080/15548627.2020.1714209DOI Listing
January 2020

Immune contexture of cholangiocarcinoma.

Curr Opin Gastroenterol 2020 Mar;36(2):70-76

Institut National de la Santé et de la Recherche Médicale (INSERM), U1138.

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http://dx.doi.org/10.1097/MOG.0000000000000613DOI Listing
March 2020

Autophagy in hepatic adaptation to stress.

J Hepatol 2020 01;72(1):183-196

Equipe labellisée par la Ligue contre le cancer, Université de Paris, Sorbonne Université, INSERM U1138, Centre de Recherche des Cordeliers, Paris, France; Université Paris Descartes/Paris V, Paris, France; Metabolomics and Cell Biology Platforms, Gustave Roussy Comprehensive Cancer Institute, Villejuif, France; Pôle de Biologie, Hôpital Européen Georges Pompidou, AP-HP, Paris, France; Suzhou Institute for Systems Medicine, Chinese Academy of Sciences, Suzhou, China; Department of Women's and Children's Health, Karolinska University Hospital, Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2019.08.026DOI Listing
January 2020

Immunological Effects of Epigenetic Modifiers.

Cancers (Basel) 2019 Dec 1;11(12). Epub 2019 Dec 1.

Equipe labellisée par la Ligue contre le cancer, 75000 Paris, France.

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http://dx.doi.org/10.3390/cancers11121911DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966579PMC
December 2019

Immunosuppression by Mutated Calreticulin Released from Malignant Cells.

Mol Cell 2020 02 27;77(4):748-760.e9. Epub 2019 Nov 27.

Metabolomics and Cell Biology Platforms, Gustave Roussy Comprehensive Cancer Institute, Villejuif, France; Equipe 11 labellisée Ligue contre le Cancer, Centre de Recherche des Cordeliers, INSERM UMR 1138, Paris, France; Sorbonne Université, Paris, France; Université of Paris, Paris, France; Suzhou Institute for Systems Medicine, Chinese Academy of Sciences, Suzhou, China; Karolinska Institutet, Department of Women's and Children's Health, Stockholm, Sweden; Pôle de Biologie, Hôpital Européen Georges Pompidou, AP-HP, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2019.11.004DOI Listing
February 2020

Immunostimulatory gut bacteria.

Science 2019 11;366(6469):1077-1078

Suzhou Institute for Systems Biology, Chinese Academy of Medical Sciences, Suzhou, China.

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http://dx.doi.org/10.1126/science.aaz7595DOI Listing
November 2019

Assessment of annexin A1 release during immunogenic cell death.

Methods Enzymol 2019 2;629:71-79. Epub 2019 Jul 2.

Equipe labellisée Ligue Nationale Contre le Cancer, Université Paris Descartes, Université Sorbonne Paris Cité, Université Paris Diderot, Institut National de la Santé et de la Recherche Médicale (INSERM), UMR1138, Centre de Recherche des Cordeliers, Paris, France; Metabolomics and Cell Biology Platforms, Institut Gustave Roussy, Villejuif, France; Pôle de Biologie, Hôpital Européen Georges Pompidou, AP-HP, Paris, France; Suzhou Institute for Systems Medicine, Chinese Academy of Medical Sciences, Suzhou, China; Department of Women's and Children's Health, Karolinska Institute, Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1016/bs.mie.2019.06.010DOI Listing
June 2020

Quantification of eIF2alpha phosphorylation during immunogenic cell death.

Methods Enzymol 2019 27;629:53-69. Epub 2019 Apr 27.

Equipe labellisée Ligue Nationale Contre le Cancer, Université Paris Descartes, Université Sorbonne Paris Cité, Université Paris Diderot, Institut National de la Santé et de la Recherche Médicale (INSERM), UMR1138, Centre de Recherche des Cordeliers, Paris, France; Metabolomics and Cell Biology Platforms, Institut Gustave Roussy, Villejuif, France. Electronic address:

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http://dx.doi.org/10.1016/bs.mie.2019.04.010DOI Listing
June 2020

Methods for measuring HMGB1 release during immunogenic cell death.

Methods Enzymol 2019 27;629:177-193. Epub 2019 May 27.

Cell Biology and Metabolomics Platforms, Gustave Roussy Cancer Campus, Villejuif, France; Equipe 11 labellisée Ligue Nationale contre le Cancer, Centre de Recherche des Cordeliers, Paris, France; Equipe labellisée Ligue Nationale Contre le Cancer, Université Paris Descartes, Université Sorbonne Paris Cité, Université Paris Diderot, Institut National de la Santé et de la Recherche Médicale (INSERM), UMR1138, Centre de Recherche des Cordeliers, Paris, France; Université Paris Descartes, Sorbonne Paris Cité, Paris, France; Université Pierre et Marie Curie, Paris, France; Suzhou Institute of Systems Medicine, Chinese Academy of Medical Sciences, Suzhou, China; Pôle de Biologie, Hôpital Européen Georges Pompidou, AP-HP, Paris, France; Department of Women's and Children's Health, Karolinska Institute, Karolinska University Hospital, Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/bs.mie.2019.05.001DOI Listing
June 2020

Quinacrine-mediated detection of intracellular ATP.

Methods Enzymol 2019 17;629:103-113. Epub 2019 Jun 17.

Faculty of Medicine, University of Paris Sud, Kremlin-Bicêtre, France; Cell Biology and Metabolomics Platforms, Gustave Roussy Cancer Campus, Villejuif, France; Equipe 11 labellisée Ligue Nationale contre le Cancer, Centre de Recherche des Cordeliers, Paris, France; Equipe labellisée Ligue Nationale Contre le Cancer, Université Paris Descartes, Université Sorbonne Paris Cité, Université Paris Diderot, Institut National de la Santé et de la Recherche Médicale (INSERM), UMR1138, Centre de Recherche des Cordeliers, Paris, France; Université Paris Descartes, Sorbonne Paris Cité, Paris, France; Université Pierre et Marie Curie, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/bs.mie.2019.05.050DOI Listing
June 2020

The elusive "hunger protein": an appetite-stimulatory factor that is overabundant in human obesity.

Mol Cell Oncol 2019 15;6(6):e1667193. Epub 2019 Oct 15.

INSERM U1138, Centre de Recherche des Cordeliers, Sorbonne Université, Université de Paris, Paris, France.

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http://dx.doi.org/10.1080/23723556.2019.1667193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6816372PMC
October 2019

A discovery platform for the identification of caloric restriction mimetics with broad health-improving effects.

Autophagy 2020 01 7;16(1):188-189. Epub 2019 Nov 7.

Equipe 11 labellisée Ligue contre le Cancer, Centre de Recherche des Cordeliers, INSERM U 1138, Paris, France.

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http://dx.doi.org/10.1080/15548627.2019.1688984DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984457PMC
January 2020

BML-265 and Tyrphostin AG1478 Disperse the Golgi Apparatus and Abolish Protein Transport in Human Cells.

Front Cell Dev Biol 2019 11;7:232. Epub 2019 Oct 11.

Dynamics of Intracellular Organization Laboratory, Institut Curie, PSL Research University, Sorbonne Université, Centre National de la Recherche Scientifique, UMR 144, Paris, France.

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http://dx.doi.org/10.3389/fcell.2019.00232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797785PMC
October 2019

Acyl-CoA-binding protein (ACBP): the elusive 'hunger factor' linking autophagy to food intake.

Cell Stress 2019 Sep 24;3(10):312-318. Epub 2019 Sep 24.

INSERM U1138, Centre de Recherche des Cordeliers, Sorbonne Université, Université de Paris, 15 rue de l'école de médecine 75006, Paris, France.

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http://dx.doi.org/10.15698/cst2019.10.200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789435PMC
September 2019

Lurbinectedin synergizes with immune checkpoint blockade to generate anticancer immunity.

Oncoimmunology 2019 5;8(11):e1656502. Epub 2019 Sep 5.

Metabolomics and Cell Biology Platforms, Gustave Roussy Comprehensive Cancer Institute, Villejuif, France.

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http://dx.doi.org/10.1080/2162402X.2019.1656502DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791417PMC
September 2019

Trial watch: dendritic cell vaccination for cancer immunotherapy.

Oncoimmunology 2019 18;8(11):e1638212. Epub 2019 Jul 18.

Cell Death Research & Therapy (CDRT) unit, Department of Cellular & Molecular Medicine, KU Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1080/2162402X.2019.1638212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791419PMC
July 2019

Suppression of tumor antigen presentation during aneuploid tumor evolution contributes to immune evasion.

Oncoimmunology 2019 6;8(11):1657374. Epub 2019 Sep 6.

Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

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http://dx.doi.org/10.1080/2162402X.2019.1657374DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791449PMC
September 2019

Clinical evidence that immunogenic cell death sensitizes to PD-1/PD-L1 blockade.

Oncoimmunology 2019 22;8(10):e1637188. Epub 2019 Jul 22.

Suzhou Institute for Systems Medicine, Chinese Academy of Medical Sciences, Suzhou, China.

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http://dx.doi.org/10.1080/2162402X.2019.1637188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791413PMC
July 2019

Pseudodiabetes-not a contraindication for metabolic interventions.

Cell Death Dis 2019 10 10;10(10):765. Epub 2019 Oct 10.

INSERM U1138, Centre de Recherche des Cordeliers, Sorbonne Université, Université de Paris, Paris, France.

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http://dx.doi.org/10.1038/s41419-019-2007-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787197PMC
October 2019

Oncolysis without viruses - inducing systemic anticancer immune responses with local therapies.

Nat Rev Clin Oncol 2020 01 8;17(1):49-64. Epub 2019 Oct 8.

Equipe labellisée par la Ligue contre le cancer, Université de Paris, Sorbonne Université, INSERM U1138, Centre de Recherche des Cordeliers, Paris, France.

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http://dx.doi.org/10.1038/s41571-019-0272-7DOI Listing
January 2020

HIV-1 Envelope Overcomes NLRP3-Mediated Inhibition of F-Actin Polymerization for Viral Entry.

Cell Rep 2019 09;28(13):3381-3394.e7

Cell Death and Aging Team, Gustave Roussy, 114 rue Edouard Vaillant, F-94805 Villejuif, France; Laboratory of Molecular Radiotherapy, INSERM U1030, Gustave Roussy, 114 rue Edouard Vaillant, F-94805 Villejuif, France; Gustave Roussy, 114 rue Edouard Vaillant, F-94805 Villejuif, France; Université Paris Sud - Paris 11, 114 rue Edouard Vaillant, F-94805 Villejuif, France; Department of Biomedical Sciences, University of the Pacific, Arthur A. Dugoni School of Dentistry, 155 Fifth Street, San Francisco, CA 94103, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.02.095DOI Listing
September 2019

Leptin-Producing Oncolytic Virus Makes Tumor-Infiltrating T Cells Fit, Not Fat.

Immunity 2019 09;51(3):423-425

Suzhou Institute for Systems Medicine, Chinese Academy of Medical Sciences, Suzhou, China; Faculty of Medicine, Paris Sud/Paris XI University, Le Kremlin-Bicêtre, France; Gustave Roussy Comprehensive Cancer Institute, Villejuif, France; INSERM U1015, Villejuif, France; Center of Clinical Investigations in Biotherapies of Cancer (CICBT) 1428, Villejuif, France.

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http://dx.doi.org/10.1016/j.immuni.2019.08.010DOI Listing
September 2019

A strategy for poisoning cancer cell metabolism: Inhibition of oxidative phosphorylation coupled to anaplerotic saturation.

Int Rev Cell Mol Biol 2019 29;347:27-37. Epub 2019 Jul 29.

Centre de Recherche des Cordeliers, INSERM, Sorbonne Université, Université de Paris, Equipe 11 labellisée par la Ligue contre le Cancer, Paris, France; Metabolomics and Cell Biology Platforms, Institut Gustave Roussy, Villejuif, France; Pôle de Biologie, Hôpital Européen Georges Pompidou, AP-HP, Paris, France; Suzhou Institute for Systems Medicine, Chinese Academy of Sciences, Suzhou, China; Karolinska Institute, Department of Women's and Children's Health, Karolinska University Hospital, Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/bs.ircmb.2019.07.002DOI Listing
March 2020

Acyl-CoA-Binding Protein Is a Lipogenic Factor that Triggers Food Intake and Obesity.

Cell Metab 2019 10 15;30(4):754-767.e9. Epub 2019 Aug 15.

INSERM U1138, Centre de Recherche des Cordeliers, Sorbonne Université, Université de Paris, Paris, France; Team "Metabolism, Cancer & Immunity", Équipe 11 labellisée par la Ligue contre le Cancer, Paris, France; Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Campus, Villejuif, France; Pôle de Biologie, Hôpital Européen Georges Pompidou, AP-HP, Paris, France; Suzhou Institute for Systems Medicine, Chinese Academy of Sciences, Suzhou, China; Karolinska Institute, Department of Women's and Children's Health, Karolinska University Hospital, Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2019.07.010DOI Listing
October 2019

A fluorescent biosensor-based platform for the discovery of immunogenic cancer cell death inducers.

Oncoimmunology 2019 26;8(8):1606665. Epub 2019 Apr 26.

Metabolomics and Cell Biology Platforms, Gustave Roussy Comprehensive Cancer Institute, Villejuif, France.

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http://dx.doi.org/10.1080/2162402X.2019.1606665DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682369PMC
April 2019

Oxidative phosphorylation as a potential therapeutic target for cancer therapy.

Int J Cancer 2020 01 11;146(1):10-17. Epub 2019 Sep 11.

Equipe labellisée par la Ligue contre le cancer, Université de Paris, Sorbonne Université, INSERM U1138, Centre de Recherche des Cordeliers, Paris, France.

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http://dx.doi.org/10.1002/ijc.32616DOI Listing
January 2020

Optimising efficacy and reducing toxicity of anticancer radioimmunotherapy.

Lancet Oncol 2019 08 29;20(8):e452-e463. Epub 2019 Jul 29.

Metabolomics and Cell Biology Platforms, Gustave Roussy Comprehensive Cancer Center, Villejuif, France; Université Paris Descartes/Paris V, Paris, France; Equipe Labellisée par la Ligue Contre Le Cancer, Université Paris Descartes, Université Paris Diderot, Sorbonne Paris Université Cité, INSERM U1138, Centre de Recherche des Cordeliers, Paris, France; Pôle de Biologie, Hôpital Européen Georges Pompidou, AP-HP, Paris, France; Suzhou Institute for Systems Medicine, Chinese Academy of Sciences, Suzhou, China; Department of Women's and Children's Health, Karolinska University Hospital, Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(19)30171-8DOI Listing
August 2019

Clockophagy is a novel selective autophagy process favoring ferroptosis.

Sci Adv 2019 07 24;5(7):eaaw2238. Epub 2019 Jul 24.

The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong 510510, China.

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http://dx.doi.org/10.1126/sciadv.aaw2238DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656546PMC
July 2019

Healthspan and lifespan extension by fecal microbiota transplantation into progeroid mice.

Nat Med 2019 08 22;25(8):1234-1242. Epub 2019 Jul 22.

Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Instituto Universitario de Oncología (IUOPA), Universidad de Oviedo, Oviedo, Spain.

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http://dx.doi.org/10.1038/s41591-019-0504-5DOI Listing
August 2019

Macrophages and Metabolism in the Tumor Microenvironment.

Cell Metab 2019 07;30(1):36-50

Université Paris Descartes, Paris, France; Department of Radiation Oncology, Weill Cornell Medical College, New York, NY, USA; Sandra and Edward Meyer Cancer Center, New York, NY, USA; Department of Dermatology, Yale University School of Medicine, New Haven, CT, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2019.06.001DOI Listing
July 2019

Autophagy represses hepatic carcinogenesis.

Mol Cell Oncol 2019 13;6(4):1573080. Epub 2019 May 13.

Equipe 11 labellisée par la Ligue contre le Cancer, Centre de Recherche des Cordeliers, Paris, France.

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http://dx.doi.org/10.1080/23723556.2019.1573080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548487PMC
May 2019