Publications by authors named "Guenther Boden"

87Publications

Duodenal GLP-1 signaling regulates hepatic glucose production through a PKC-δ-dependent neurocircuitry.

Cell Death Dis 2017 02 9;8(2):e2609. Epub 2017 Feb 9.

Department of Endocrinology, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.

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http://dx.doi.org/10.1038/cddis.2017.28DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386475PMC
February 2017

Excessive caloric intake acutely causes oxidative stress, GLUT4 carbonylation, and insulin resistance in healthy men.

Sci Transl Med 2015 Sep;7(304):304re7

Department of Pharmaceutical Sciences and Moulder Center for Drug Discovery, Proteomics/Metabolomics Facility, Temple University School of Pharmacy, Philadelphia, PA 19140, USA.

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http://dx.doi.org/10.1126/scitranslmed.aac4765DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600191PMC
September 2015

Tissue factor and Toll-like receptor (TLR)4 in hyperglycaemia-hyperinsulinaemia. Effects in healthy subjects, and type 1 and type 2 diabetes mellitus.

Thromb Haemost 2015 Apr 5;113(4):750-8. Epub 2015 Feb 5.

A. Koneti Rao, M.B.B.S., Temple University School of Medicine, Sol Sherry Thrombosis Research Center, 3400 North Broad Street, Philadelphia, PA 19140, USA, Tel.: +1 215 707 4684, Fax: +1 215 707 2783, E-mail:

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http://dx.doi.org/10.1160/TH14-10-0884DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4677063PMC
April 2015

Overexpression of JAZF1 protected ApoE-deficient mice from atherosclerosis by inhibiting hepatic cholesterol synthesis via CREB-dependent mechanisms.

Int J Cardiol 2014 Nov 11;177(1):100-10. Epub 2014 Oct 11.

The Key Laboratory of Laboratory Medical Diagnostics in the Ministry of Education and Department of Clinical Biochemistry, College of Laboratory Medicine, Chongqing Medical University, 400016 Chongqing, China. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2014.09.007DOI Listing
November 2014

Alterations in insulin-signaling and coagulation pathways in platelets during hyperglycemia-hyperinsulinemia in healthy non-diabetic subject.

Thromb Res 2014 Sep 6;134(3):704-10. Epub 2014 Jul 6.

Department of Medicine, Temple University School of Medicine, Philadelphia, PA, USA; General Clinical Research Center, Temple University School of Medicine, Philadelphia, PA, USA.

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http://dx.doi.org/10.1016/j.thromres.2014.06.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148207PMC
September 2014

Insulin resistance is associated with diminished endoplasmic reticulum stress responses in adipose tissue of healthy and diabetic subjects.

Diabetes 2014 Sep 16;63(9):2977-83. Epub 2014 Apr 16.

Department of Surgery, Temple University School of Medicine, Philadelphia, PA.

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http://dx.doi.org/10.2337/db14-0055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141374PMC
September 2014

Silencing of FGF-21 expression promotes hepatic gluconeogenesis and glycogenolysis by regulation of the STAT3-SOCS3 signal.

FEBS J 2014 May 1;281(9):2136-47. Epub 2014 Apr 1.

Key Laboratory of Diagnostic Medicine (Ministry of Education) and Department of Clinical Biochemistry, College of Laboratory Medicine, Chongqing Medical University, 400016, China.

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http://dx.doi.org/10.1111/febs.12767DOI Listing
May 2014

Efficacy and safety of aldose reductase inhibitor for the treatment of diabetic cardiovascular autonomic neuropathy: systematic review and meta-analysis.

PLoS One 2014 12;9(2):e87096. Epub 2014 Feb 12.

Key Laboratory of Diagnostic Medicine (Ministry of Education) and Department of Clinical Biochemistry, College of Laboratory Medicine, Chongqing Medical University, Chongqing, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0087096PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922720PMC
January 2015

Hypothalamic nesfatin-1/NUCB2 knockdown augments hepatic gluconeogenesis that is correlated with inhibition of mTOR-STAT3 signaling pathway in rats.

Diabetes 2014 Apr 29;63(4):1234-47. Epub 2014 Jan 29.

Department of Endocrinology, Second Affiliated Hospital, and Key Laboratory of Laboratory Medical Diagnostics (Ministry of Education), Chongqing Medical University, Chongqing, China.

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http://dx.doi.org/10.2337/db13-0899DOI Listing
April 2014

Changes in insulin sensitivity and insulin secretion with the sodium glucose cotransporter 2 inhibitor dapagliflozin.

Diabetes Technol Ther 2014 Mar 15;16(3):137-44. Epub 2013 Nov 15.

1 Center for Metabolic Research, VA San Diego Healthcare System, and University of California , San Diego, San Diego, California.

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http://dx.doi.org/10.1089/dia.2013.0167DOI Listing
March 2014

Insulin regulates the unfolded protein response in human adipose tissue.

Diabetes 2014 Mar 15;63(3):912-22. Epub 2013 Oct 15.

Division of Endocrinology/Diabetes/Metabolism, Temple University School of Medicine, Philadelphia, PA.

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http://dx.doi.org/10.2337/db13-0906DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931405PMC
March 2014

Comparison of in vivo effects of insulin on SREBP-1c activation and INSIG-1/2 in rat liver and human and rat adipose tissue.

Obesity (Silver Spring) 2013 Jun;21(6):1208-14

Division of Endocrinology/Diabetes/Metabolism, Clinical Research Center, Temple University School of Medicine, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1002/oby.20134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740458PMC
June 2013

A Single A1C >= 6.5% Accurately Identifies Type 2 Diabetes/Impaired Glucose Tolerance in African Americans.

J Prim Care Community Health 2012 Oct 11;3(4):235-8. Epub 2012 Feb 11.

Clinical Research Center, Temple University School of Medicine, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1177/2150131911435526DOI Listing
October 2012

Why does obesity increase the risk for cardiovascular disease?

Curr Pharm Des 2013 ;19(32):5678-83

Division of Endocrinology, Diabetes, Metabolism and the Clinical Research Center, Temple University School of Medicine, Philadelphia, PA, USA.

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http://dx.doi.org/10.2174/1381612811319320003DOI Listing
March 2014

GLP-1 analogue prevents NAFLD in ApoE KO mice with diet and Acrp30 knockdown by inhibiting c-JNK.

Liver Int 2013 May 24;33(5):794-804. Epub 2013 Feb 24.

Department of Endocrinology, the Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.

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http://dx.doi.org/10.1111/liv.12120DOI Listing
May 2013

Systematic review of the effectiveness of hyperbaric oxygenation therapy in the management of chronic diabetic foot ulcers.

Mayo Clin Proc 2013 Feb;88(2):166-75

Department of Endocrinology, the Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.

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http://dx.doi.org/10.1016/j.mayocp.2012.10.021DOI Listing
February 2013

Liraglutide increases FGF-21 activity and insulin sensitivity in high fat diet and adiponectin knockdown induced insulin resistance.

PLoS One 2012 12;7(11):e48392. Epub 2012 Nov 12.

Key Laboratory of Diagnostic Medicine (Ministry of Education) and Department of Clinical Biochemistry, College of Laboratory Medicine, Chongqing Medical University, Chongqing, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0048392PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495944PMC
May 2013

Nesfatin-1 action in the brain increases insulin sensitivity through Akt/AMPK/TORC2 pathway in diet-induced insulin resistance.

Diabetes 2012 Aug 11;61(8):1959-68. Epub 2012 Jun 11.

Department of Endocrinology, Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.

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http://diabetes.diabetesjournals.org/cgi/doi/10.2337/db11-17
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http://dx.doi.org/10.2337/db11-1755DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402309PMC
August 2012

Long-term high-fat diet links the regulation of the insulin-sensitizing fibroblast growth factor-21 and visfatin.

Cytokine 2012 Jul 27;59(1):131-7. Epub 2012 Apr 27.

The Key Laboratory of Laboratory Medical Diagnostics in the Ministry of Education, Chongqing Medical University, 400016 Chongqing, China.

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http://dx.doi.org/10.1016/j.cyto.2012.03.030DOI Listing
July 2012

Whole-blood tissue factor procoagulant activity is elevated in type 1 diabetes: effects of hyperglycemia and hyperinsulinemia.

Diabetes Care 2012 Jun 12;35(6):1322-7. Epub 2012 Mar 12.

Sol Sherry Thrombosis Research Center, Temple University School of Medicine, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.2337/dc11-2114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357241PMC
June 2012

Does inhibition of β-cell proliferation by free fatty acid in mice explain the progressive failure of insulin secretion in type 2 diabetes?

Authors:
Guenther Boden

Diabetes 2012 Mar;61(3):560-1

Division of Endocrinology, Diabetes, and Metabolism, Temple University School of Medicine, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.2337/db11-1613DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282813PMC
March 2012

Mitiglinide treatment may decreases plasma fibroblast growth factor-21 levels in individuals with new-onset T2DM.

Cytokine 2012 Feb 29;57(2):300-3. Epub 2011 Nov 29.

The Key Laboratory of Laboratory Medical Diagnostics in the Ministry of Education, Department of Clinical Biochemistry, College of Laboratory Medicine, Chongqing Medical University, 400016 Chongqing, China.

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http://dx.doi.org/10.1016/j.cyto.2011.11.002DOI Listing
February 2012

The effects of fibroblast growth factor-21 knockdown and over-expression on its signaling pathway and glucose-lipid metabolism in vitro.

Mol Cell Endocrinol 2012 Jan 27;348(1):21-6. Epub 2011 Jul 27.

Department of Endocrinology, The Second Affiliated Hospital, Chongqing Medical University, 400010 Chongqing, China.

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http://linkinghub.elsevier.com/retrieve/pii/S030372071100406
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http://dx.doi.org/10.1016/j.mce.2011.07.026DOI Listing
January 2012

The individual and combined effects of glycemic index and protein on glycemic response, hunger, and energy intake.

Obesity (Silver Spring) 2011 Dec 30;19(12):2365-73. Epub 2011 Jun 30.

Center for Obesity Research and Education, Temple University School of Medicine, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1038/oby.2011.145DOI Listing
December 2011

Infusion of glucose and lipids at physiological rates causes acute endoplasmic reticulum stress in rat liver.

Obesity (Silver Spring) 2011 Jul 7;19(7):1366-73. Epub 2011 Apr 7.

Division of Endocrinology/Diabetes/Metabolism and the Clinical Research Center, Temple University School of Medicine, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1038/oby.2011.71DOI Listing
July 2011

Short-term continuous subcutaneous insulin infusion decreases the plasma vaspin levels in patients with type 2 diabetes mellitus concomitant with improvement in insulin sensitivity.

Eur J Endocrinol 2011 Jun 6;164(6):905-10. Epub 2011 Apr 6.

Department of Endocrinology, The Second Affiliated Hospital, Chongqing Medical University, 400016 Chongqing, China.

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http://dx.doi.org/10.1530/EJE-10-1023DOI Listing
June 2011

Effects of the long-acting human glucagon-like peptide-1 analog liraglutide on plasma omentin-1 levels in patients with type 2 diabetes mellitus.

Diabetes Res Clin Pract 2011 Jun 31;92(3):368-74. Epub 2011 Mar 31.

Department of Endocrinology, the Second Affiliated Hospital, Chongqing Medical University, 400010 Chongqing, China.

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http://linkinghub.elsevier.com/retrieve/pii/S016882271100114
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http://dx.doi.org/10.1016/j.diabres.2011.02.030DOI Listing
June 2011

Obesity, insulin resistance and free fatty acids.

Authors:
Guenther Boden

Curr Opin Endocrinol Diabetes Obes 2011 Apr;18(2):139-43

Division of Endocrinology, Diabetes, Metabolism and the Clinical Research Center, Temple University School of Medicine, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1097/MED.0b013e3283444b09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169796PMC
April 2011

Type 2 diabetes in mice induces hepatic overexpression of sulfatase 2, a novel factor that suppresses uptake of remnant lipoproteins.

Hepatology 2010 Dec 3;52(6):1957-67. Epub 2010 Nov 3.

Section of Endocrinology, Diabetes and Metabolism, Temple University School of Medicine, Philadelphia, PA 19140, USA.

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http://dx.doi.org/10.1002/hep.23916DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991429PMC
December 2010

Elevated plasma levels of chemerin in newly diagnosed type 2 diabetes mellitus with hypertension.

J Investig Med 2010 Oct;58(7):883-6

Department of Clinical Biochemistry and Key Laboratory of Laboratory Medical Diagnostics in Ministry of Education, Chongqing Medical University, Chongqing, China.

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http://dx.doi.org/10.231/JIM.0b013e3181ec5db2DOI Listing
October 2010

Pulsatile intermittent intravenous insulin therapy for attenuation of retinopathy and nephropathy in type 1 diabetes mellitus.

Metabolism 2010 Oct 1;59(10):1429-34. Epub 2010 Mar 1.

William P. Beetham Eye and John Cook Renal Units, Joslin Diabetes Center, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.metabol.2010.01.004DOI Listing
October 2010

Insulin-sensitivity response to a single bout of resistive exercise in type 1 diabetes mellitus.

J Sport Rehabil 2009 Nov;18(4):564-71

Dept of Sports Medicine, West Chester University, West Chester, PA, USA.

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http://dx.doi.org/10.1123/jsr.18.4.564DOI Listing
November 2009

Acute tissue injury caused by subcutaneous fat biopsies produces endoplasmic reticulum stress.

J Clin Endocrinol Metab 2010 Jan 6;95(1):349-52. Epub 2009 Nov 6.

Division of Endocrinology/Diabetes/Metabolism and the Clinical Research, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA.

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http://dx.doi.org/10.1210/jc.2009-1815DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2805497PMC
January 2010

Endoplasmic reticulum stress: another link between obesity and insulin resistance/inflammation?

Authors:
Guenther Boden

Diabetes 2009 Mar;58(3):518-9

Division of Endocrinology, Diabetes, and Metabolism, Temple University School of Medicine, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.2337/db08-1746DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646047PMC
March 2009

The adipose triglyceride lipase, adiponectin and visfatin are downregulated by tumor necrosis factor-alpha (TNF-alpha) in vivo.

Cytokine 2009 Jan 20;45(1):12-9. Epub 2008 Nov 20.

The Key Laboratory of Laboratory Medical Diagnostics in the Ministry of Education, Department of Clinical Biochemistry, Chongqing Medical University, 400016 Chongqing, China.

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http://linkinghub.elsevier.com/retrieve/pii/S104346660800765
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http://dx.doi.org/10.1016/j.cyto.2008.10.006DOI Listing
January 2009

Obesity and free fatty acids.

Authors:
Guenther Boden

Endocrinol Metab Clin North Am 2008 Sep;37(3):635-46, viii-ix

Department of Medicine, Division of Endocrinology/Diabetes/Metabolism, Temple University School of Medicine, Temple University Hospital, 3401 North Broad Street, Philadelphia, PA 19140, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S088985290800033
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http://dx.doi.org/10.1016/j.ecl.2008.06.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2596919PMC
September 2008

Effects of hyperinsulinemia on hepatic metalloproteinases and their tissue inhibitors.

Am J Physiol Endocrinol Metab 2008 Sep 29;295(3):E692-7. Epub 2008 Jul 29.

Temple University Hospital, Philadelphia, PA 19140, USA.

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http://www.physiology.org/doi/10.1152/ajpendo.90370.2008
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http://dx.doi.org/10.1152/ajpendo.90370.2008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2536734PMC
September 2008

Effects of insulin and free fatty acids on matrix metalloproteinases.

Curr Diab Rep 2008 Jun;8(3):239-42

Temple University Hospital, 3401 North Broad Street, Philadelphia, PA 19140, USA.

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http://dx.doi.org/10.1007/s11892-008-0041-yDOI Listing
June 2008

Increased insulin resistance in young adults born with very low birth weight.

Authors:
Guenther Boden

Curr Diab Rep 2008 Jun;8(3):231-2

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http://dx.doi.org/10.1007/s11892-008-0039-5DOI Listing
June 2008

Circulating preptin levels in normal, impaired glucose tolerance, and type 2 diabetic subjects.

Ann Med 2009 ;41(1):52-6

Department of Endocrinology, Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.

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http://www.tandfonline.com/doi/full/10.1080/0785389080224414
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http://dx.doi.org/10.1080/07853890802244142DOI Listing
March 2009

[Effects of visfatin gene overexpression on insulin sensitivity in the insulin-resistant rats induced by high-fat diet].

Zhonghua Yi Xue Za Zhi 2008 Feb;88(6):365-8

Department of Endocrinology, Second Affiliated Hospital, Chongqing Medical University, Chongqing 400010, China.

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February 2008

Increase in endoplasmic reticulum stress-related proteins and genes in adipose tissue of obese, insulin-resistant individuals.

Diabetes 2008 Sep 20;57(9):2438-44. Epub 2008 Jun 20.

Division of Endocrinology, Diabetes, and Metabolism and the Clinical Research Center, Temple University School of Medicine, Philadelphia, Pennsylvania, USA.

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http://diabetes.diabetesjournals.org/cgi/doi/10.2337/db08-06
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http://dx.doi.org/10.2337/db08-0604DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518495PMC
September 2008

In vivo effects of insulin and free fatty acids on matrix metalloproteinases in rat aorta.

Diabetes 2008 Feb 19;57(2):476-83. Epub 2007 Nov 19.

Temple University Hospital, 3401 North Broad St., Philadelphia, PA 19140, USA.

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http://dx.doi.org/10.2337/db07-1261DOI Listing
February 2008

Circulating tissue factor procoagulant activity and thrombin generation in patients with type 2 diabetes: effects of insulin and glucose.

J Clin Endocrinol Metab 2007 Nov 4;92(11):4352-8. Epub 2007 Sep 4.

Division of Endocrinology/Diabetes/Metabolism and the Clinical Research Center, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA.

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https://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.
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http://dx.doi.org/10.1210/jc.2007-0933DOI Listing
November 2007

Pioglitazone and nonalcoholic steatohepatitis.

Authors:
Guenther Boden

Curr Diab Rep 2007 Jun;7(3):221-2

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http://dx.doi.org/10.1007/s11892-007-0034-2DOI Listing
June 2007

Effects of hyperglycemia and hyperinsulinemia on the tissue factor pathway of blood coagulation.

Curr Diab Rep 2007 Jun;7(3):223-7

Division of Endocrinology/Diabetes/Metabolism and the Clinical Research Center, Temple University Hospital, 3401 N. Broad Street, Philadelphia, PA 19140, USA.

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http://dx.doi.org/10.1007/s11892-007-0035-1DOI Listing
June 2007

Circulating obestatin levels in normal subjects and in patients with impaired glucose regulation and type 2 diabetes mellitus.

Clin Endocrinol (Oxf) 2007 Apr;66(4):593-7

Department of Endocrinology, The Second Affiliated Hospital, Chongqing University of Medical Sciences, Chongqing, China.

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http://dx.doi.org/10.1111/j.1365-2265.2007.02776.xDOI Listing
April 2007

Differential effects of somatostatin on circulating tissue factor procoagulant activity and protein.

Am J Physiol Endocrinol Metab 2007 May 9;292(5):E1333-9. Epub 2007 Jan 9.

Division of Endocrinology, Diabetes, and Metabolism and the Clinical Research Center, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA.

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http://dx.doi.org/10.1152/ajpendo.00483.2006DOI Listing
May 2007

Combined use of rosiglitazone and fenofibrate in patients with type 2 diabetes: prevention of fluid retention.

Diabetes 2007 Jan;56(1):248-55

Division of Endocrinology/Diabetes/Metabolism, Clinical Research Unit, Temple University School of Medicine, Philadelphia, PA, USA.

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http://diabetes.diabetesjournals.org/cgi/doi/10.2337/db06-04
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http://dx.doi.org/10.2337/db06-0481DOI Listing
January 2007

Platelet and monocyte activation by hyperglycemia and hyperinsulinemia in healthy subjects.

Platelets 2006 Dec;17(8):577-85

Sol Sherry Thrombosis Research Center, Temple University School of Medicine, Philadelphia, PA 19140, USA.

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http://www.tandfonline.com/doi/full/10.1080/0953710060076081
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http://dx.doi.org/10.1080/09537100600760814DOI Listing
December 2006

Fatty acid-induced inflammation and insulin resistance in skeletal muscle and liver.

Authors:
Guenther Boden

Curr Diab Rep 2006 Jun;6(3):177-81

Division of Endocrinology/Diabetes/Metabolism, Temple University School of Medicine, Temple University Hospital, 3401 North Broad Street, Philadelphia, PA 19140, USA.

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http://dx.doi.org/10.1007/s11892-006-0031-xDOI Listing
June 2006

Abnormal ghrelin and pancreatic polypeptide responses in gastroparesis.

Dig Dis Sci 2006 Aug 26;51(8):1339-46. Epub 2006 Jul 26.

Section of Gastroenterology, Department of Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1007/s10620-005-9022-zDOI Listing
August 2006

Obesity, insulin resistance, Type 2 diabetes and free fatty acids.

Authors:
Guenther Boden

Expert Rev Endocrinol Metab 2006 Jul;1(4):499-505

a Professor of Medicine, Chief Division Endocrinology/Diabetes/Metabolism Temple University School of Medicine, Philadelphia, PA 19140, USA.

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http://dx.doi.org/10.1586/17446651.1.4.499DOI Listing
July 2006

Recent findings concerning thiazolidinediones in the treatment of diabetes.

Expert Opin Investig Drugs 2006 Mar;15(3):243-50

Division of Endocrinology/Diabetes/Metabolism, Temple University School of Medicine, Philadelphia, PA, USA.

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http://dx.doi.org/10.1517/13543784.15.3.243DOI Listing
March 2006

Effects of hyperglycemia and hyperinsulinemia on circulating tissue factor procoagulant activity and platelet CD40 ligand.

Diabetes 2006 Jan;55(1):202-8

Temple University Hospital, 3401 North Broad Street, Philadelphia, PA 19140, USA.

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January 2006

Short-term pioglitazone treatment prevents free fatty acid-induced hepatic insulin resistance in normal rats: possible role of the resistin and adiponectin.

Biochem Biophys Res Commun 2006 Jan 5;339(4):1190-6. Epub 2005 Dec 5.

Department of Endocrinology, The Second Affiliated Hospital, Chongqing University of Medical Sciences, Chongqing 400010, China.

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http://dx.doi.org/10.1016/j.bbrc.2005.11.143DOI Listing
January 2006

Free fatty acids produce insulin resistance and activate the proinflammatory nuclear factor-kappaB pathway in rat liver.

Diabetes 2005 Dec;54(12):3458-65

Division of Endocrinology, Diabetes, and Metabolism, Temple University School of Medicine, 3401 North Broad St., Philadelphia, Pennsylvania 19140, USA.

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http://dx.doi.org/10.2337/diabetes.54.12.3458DOI Listing
December 2005

Effects of free fatty acids on plasma resistin and insulin resistance in awake rats.

Metabolism 2005 Sep;54(9):1142-6

Department of Endocrinology, The Second Affiliated Hospital, Chongqing Medical University, Chongqing 400010, China.

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http://linkinghub.elsevier.com/retrieve/pii/S002604950500143
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http://dx.doi.org/10.1016/j.metabol.2005.03.020DOI Listing
September 2005

Free fatty acids and insulin secretion in humans.

Authors:
Guenther Boden

Curr Diab Rep 2005 Jun;5(3):167-70

Division of Endocrinology/Diabetes/Metabolism, Temple University School of Medicine, Temple University Hospital, 3401 North Broad Street, Philadelphia, PA 19140, USA.

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http://dx.doi.org/10.1007/s11892-005-0004-5DOI Listing
June 2005

New benefits of statin treatment.

Authors:
Guenther Boden

Curr Diab Rep 2005 Jun;5(3):165; discussion 165-6

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http://dx.doi.org/10.1007/s11892-005-0003-6DOI Listing
June 2005

Effect of high protein vs high carbohydrate intake on insulin sensitivity, body weight, hemoglobin A1c, and blood pressure in patients with type 2 diabetes mellitus.

J Am Diet Assoc 2005 Apr;105(4):573-80

Nutrition Center, Department of Bioscience and Biotechnology, Drexel University, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.jada.2005.01.009DOI Listing
April 2005

Effect of a low-carbohydrate diet on appetite, blood glucose levels, and insulin resistance in obese patients with type 2 diabetes.

Ann Intern Med 2005 Mar;142(6):403-11

Temple University School of Medicine, Philadelphia, Pennsylvania, and University of Medicine and Dentistry of New Jersey School of Osteopathic Medicine, Stratford, New Jersey.

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http://dx.doi.org/10.7326/0003-4819-142-6-200503150-00006DOI Listing
March 2005

Thiazolidinediones upregulate fatty acid uptake and oxidation in adipose tissue of diabetic patients.

Diabetes 2005 Mar;54(3):880-5

Division of Endocrinology, Diabetes and Metabolism, Temple University School of Medicine, Philadelphia, PA, USA.

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http://dx.doi.org/10.2337/diabetes.54.3.880DOI Listing
March 2005

Gluconeogenesis and glycogenolysis in health and diabetes.

Authors:
Guenther Boden

J Investig Med 2004 Sep;52(6):375-8

Division of Endocrinology/Diabetes/Metabolism, Temple University School of Medicine, Philadelphia, PA 19140, USA.

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http://dx.doi.org/10.1136/jim-52-06-31DOI Listing
September 2004

Lipids and glucose in type 2 diabetes: what is the cause and effect?

Diabetes Care 2004 Sep;27(9):2253-9

Division of Endocrinology/Diabetes/Metabolism and the General Clinical Research Center, Temple University Hospital, 3401 N. Broad St., Philadelphia, PA 19140, USA.

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http://dx.doi.org/10.2337/diacare.27.9.2253DOI Listing
September 2004

Milrinone, a selective phosphodiesterase 3 inhibitor, stimulates lipolysis, endogenous glucose production, and insulin secretion.

Metabolism 2003 Nov;52(11):1496-500

Division of Endocrinology/Diabetes/Metabolism, Clinical Research Center, Temple University School of Medicine, Philadelphia, PA 19141, USA.

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http://dx.doi.org/10.1016/s0026-0495(03)00271-3DOI Listing
November 2003

Nerves, fat, and insulin resistance.

N Engl J Med 2003 Nov;349(20):1966-7

Department of Medicine, Temple University Hospital, Philadelphia, USA.

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http://dx.doi.org/10.1056/NEJMcibr035229DOI Listing
November 2003

Nutritional effects of fat on carbohydrate metabolism.

Best Pract Res Clin Endocrinol Metab 2003 Sep;17(3):399-410

Division of Endocrinology/Diabetes/Metabolism and the General Clinical Research Center, Temple University School of Medicine, 3401 North Broad Street, Philadelphia, PA 19140, USA.

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http://dx.doi.org/10.1016/s1521-690x(03)00032-0DOI Listing
September 2003

Free fatty acids, insulin resistance, and pregnancy.

Curr Diab Rep 2003 Aug;3(4):319-22

Division of Endocrinology/Diabetes/Metabolism, Temple University Hospital, 3401 North Broad Street, Philadelphia, PA 19140, USA.

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http://dx.doi.org/10.1007/s11892-003-0024-yDOI Listing
August 2003

Comparison of insulin aspart and lispro: pharmacokinetic and metabolic effects.

Diabetes Care 2003 Jul;26(7):2027-31

General Clinical Research Center and Division of Endocrinology/Diabetes/Metabolism, Temple University School of Medicine, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.2337/diacare.26.7.2027DOI Listing
July 2003

Effect of thiazolidinediones on glucose and fatty acid metabolism in patients with type 2 diabetes.

Metabolism 2003 Jun;52(6):753-9

Division of Endocrinology/Diabetes/Metabolism and the General Clinical Research Center, Temple University School of Medicine, Philadelphia, PA 19140, USA.

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http://dx.doi.org/10.1016/s0026-0495(03)00055-6DOI Listing
June 2003

Effect of altering gastric emptying on postprandial plasma glucose concentrations following a physiologic meal in type-II diabetic patients.

Dig Dis Sci 2003 Mar;48(3):488-97

Gastroenterology Section, Department of Internal Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA.

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http://dx.doi.org/10.1023/a:1022528414264DOI Listing
March 2003

Effects of free fatty acids on glucose uptake and utilization in healthy women.

Diabetes 2003 Feb;52(2):487-91

Division of Endocrinology/Diabetes/Metabolism and the General Clinical Research Center, Temple University School of Medicine, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.2337/diabetes.52.2.487DOI Listing
February 2003

Effects of acute insulin excess and deficiency on gluconeogenesis and glycogenolysis in type 1 diabetes.

Diabetes 2003 Jan;52(1):133-7

Division of Endocrinology/Diabetes/Metabolism and the General Clinical Research Center, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA.

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http://dx.doi.org/10.2337/diabetes.52.1.133DOI Listing
January 2003

Effects of free fatty acids on gluconeogenesis and glycogenolysis.

Authors:
Guenther Boden

Life Sci 2003 Jan;72(9):977-88

Division of Endocrinology/Diabetes/Metabolism and the General Clinical Research Center, School of Medicine, Temple University Hospital, 3401 North Broad Street, Philadelphia, PA 19140, USA.

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http://dx.doi.org/10.1016/s0024-3205(02)02350-0DOI Listing
January 2003

Interaction between free fatty acids and glucose metabolism.

Authors:
Guenther Boden

Curr Opin Clin Nutr Metab Care 2002 Sep;5(5):545-9

Division of Endocrinology/Diabetes/Metabolism and the General Clinical Research Center, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA..

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http://dx.doi.org/10.1097/00075197-200209000-00014DOI Listing
September 2002

Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alpha.

Diabetes 2002 Jul;51(7):2005-11

Diabetes Unit, Section of Endocrinology, Department of Medicine, Boston University Medical Center, Boston, MA, USA.

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http://dx.doi.org/10.2337/diabetes.51.7.2005DOI Listing
July 2002

FFA cause hepatic insulin resistance by inhibiting insulin suppression of glycogenolysis.

Am J Physiol Endocrinol Metab 2002 Jul;283(1):E12-9

Division of Endocrinology/Diabetes/Metabolism and the General Clinical Research Center, Temple University Health Sciences Center, Philadelphia, Pennsylvania 19140, USA.

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http://dx.doi.org/10.1152/ajpendo.00429.2001DOI Listing
July 2002

Obesity and diabetes mellitus--how are they linked?

Authors:
Guenther Boden

West Indian Med J 2002 Mar 7-10;51 Suppl 1:51-4

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October 2002