Gu Jian-Ren

Gu Jian-Ren

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Gu Jian-Ren

Gu Jian-Ren

Publications by authors named "Gu Jian-Ren"

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Lysyl oxidase promotes liver metastasis of gastric cancer via facilitating the reciprocal interactions between tumor cells and cancer associated fibroblasts.

EBioMedicine 2019 Nov 31;49:157-171. Epub 2019 Oct 31.

State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200240, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.10.037DOI Listing
November 2019

Alternative transcription start site selection in ACSS2 controls its nuclear localization and promotes ribosome biosynthesis in hepatocellular carcinoma.

Biochem Biophys Res Commun 2019 Jun 7;514(3):632-638. Epub 2019 May 7.

State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200240, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2019.04.193DOI Listing
June 2019

Exemestane Attenuates Hepatic Fibrosis in Rats by Inhibiting Activation of Hepatic Stellate Cells and Promoting the Secretion of Interleukin 10.

J Immunol Res 2017 10;2017:3072745. Epub 2017 Dec 10.

State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200240, China.

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http://dx.doi.org/10.1155/2017/3072745DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5804406PMC
August 2018

Elevated autocrine EDIL3 protects hepatocellular carcinoma from anoikis through RGD-mediated integrin activation.

Mol Cancer 2014 Oct 1;13:226. Epub 2014 Oct 1.

Department of Liver Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, 160 Pujian Road, Shanghai, Shanghai 200127, China.

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http://dx.doi.org/10.1186/1476-4598-13-226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200221PMC
October 2014

Monoamine oxidase A suppresses hepatocellular carcinoma metastasis by inhibiting the adrenergic system and its transactivation of EGFR signaling.

J Hepatol 2014 Jun 6;60(6):1225-34. Epub 2014 Mar 6.

State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2014.02.025DOI Listing
June 2014

[Therapeutic effect of ovarian intra-arterial infusion of GE7-delivery system-mediated HSVl-tk/ganciclovir gene therapy in a rat model of malignant ovarian tumor].

Zhonghua Zhong Liu Za Zhi 2012 Apr;34(4):245-8

Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai 200011, China.

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http://dx.doi.org/10.3760/cma.j.issn.0253-3766.2012.04.002DOI Listing
April 2012

Nicotine stimulated dendritic cells could achieve anti-tumor effects in mouse lung and liver cancer.

J Clin Immunol 2011 Feb 19;31(1):80-8. Epub 2010 Oct 19.

Department of Basic Medicine Science, Medical College, Xiamen University, Xiamen 361005, People's Republic of China.

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http://link.springer.com/10.1007/s10875-010-9459-5
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http://dx.doi.org/10.1007/s10875-010-9459-5DOI Listing
February 2011

[Evaluation of GE7-transferring system-mediated HSV(1)-tk gene transfer in a rat model of ovarian tumor via intra-arterial route].

Zhonghua Zhong Liu Za Zhi 2011 Jan;33(1):4-7

Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai 200011, China.

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January 2011

The piggyBac transposon is an integrating non-viral gene transfer vector that enhances the efficiency of GDEPT.

Cell Biol Int 2009 Apr;33(4):509-15

Obstetrics and Gynecology Hospital, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1016/j.cellbi.2009.01.017DOI Listing
April 2009

Peptide ligand-mediated liposome distribution and targeting to EGFR expressing tumor in vivo.

Int J Pharm 2008 Nov 23;363(1-2):155-61. Epub 2008 Jul 23.

School of Life Science and Biotechnology, Shanghai Jiao Tong University, Shanghai, PR China.

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http://dx.doi.org/10.1016/j.ijpharm.2008.07.012DOI Listing
November 2008

Development of efficient RNA interference system using EGF-displaying phagemid particles.

Acta Pharmacol Sin 2008 Apr;29(4):437-42

State Key Laboratory for Oncogenes and Related Genes, Shanghai Jiao Tong University, Shanghai 200032, China.

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http://dx.doi.org/10.1111/j.1745-7254.2008.00768.xDOI Listing
April 2008

Ex vivo nicotine stimulation augments the efficacy of therapeutic bone marrow-derived dendritic cell vaccination.

Clin Cancer Res 2007 Jun;13(12):3706-12

The National Laboratory for Oncogenes and Related Genes, Cancer Institute of Shanghai Jiao Tong University, Shanghai, People's Republic of China.

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http://dx.doi.org/10.1158/1078-0432.CCR-07-0028DOI Listing
June 2007

Application of EGFP-EGF fusions to explore mechanism of endocytosis of epidermal growth factor.

Acta Pharmacol Sin 2007 Jan;28(1):111-7

State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Medical College of Fudan University, Shanghai 200031, China.

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http://dx.doi.org/10.1111/j.1745-7254.2007.00481.xDOI Listing
January 2007

Ex vivo nicotine stimulation augments the efficacy of therapeutic bone marrow-derived dendritic cell vaccination.

Clin Cancer Res 2007 Jun;13(12):3706-12

The National Laboratory for Oncogenes and Related Genes, Cancer Institute of Shanghai Jiao Tong University, Shanghai, People's Republic of China.

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http://dx.doi.org/10.1158/1078-0432.CCR-07-0028DOI Listing
June 2007

Establishment of a yeast system that stably expresses human cytochrome P450 reductase: application for the study of drug metabolism of cytochrome P450s in vitro.

Protein Expr Purif 2006 Jun 20;47(2):467-76. Epub 2005 Dec 20.

Laboratory of Pharmaceutical Resource Discovery, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, No. 457, People's Republic of China.

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http://dx.doi.org/10.1016/j.pep.2005.11.022DOI Listing
June 2006

[The effects of CT120B over-expression on growth suppression and changes of gene expression profiles in lung adenocarcinoma cells].

Zhonghua Zhong Liu Za Zhi 2006 May;28(5):321-5

National Laboratory for Oncogenes and Related Genes, Shanghai Cancer Institute, Shanghai 200032, China.

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May 2006

Expression and purification of a putative tumor suppressor gene PP5715 in E. coli with growth inhibition of hepatocellular carcinoma cells.

Protein Pept Lett 2006 ;13(1):41-5

Research Center of Biotechnology, Shanghai Institutes for Biological Sciences, Graduate School of the Chinese Academy of Sciences, Shanghai 200233, China.

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http://dx.doi.org/10.2174/092986606774502171DOI Listing
April 2006

Establishment of a yeast system that stably expresses human cytochrome P450 reductase: application for the study of drug metabolism of cytochrome P450s in vitro.

Protein Expr Purif 2006 Jun 20;47(2):467-76. Epub 2005 Dec 20.

Laboratory of Pharmaceutical Resource Discovery, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, No. 457, People's Republic of China.

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http://dx.doi.org/10.1016/j.pep.2005.11.022DOI Listing
June 2006

Enhanced efficiency and specificity of ovarian cancer gene therapy in rats with a novel nonviral gene delivery system (GE7) via intraovarian artery perfusion approach.

Cancer Gene Ther 2005 Oct;12(10):810-7

Department of Gynecology, Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200011, PR China.

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http://dx.doi.org/10.1038/sj.cgt.7700845DOI Listing
October 2005

Inhibitory effect of CT120B, an alternative splice variant of CT120A, on lung cancer cell growth.

Acta Biochim Biophys Sin (Shanghai) 2005 Sep;37(9):588-92

Shanghai Medical College, Fudan University, Shanghai 200032, China.

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http://dx.doi.org/10.1111/j.1745-7270.2005.00091.xDOI Listing
September 2005

cDNA expression array analysis of gene expression in human hepatocarcinoma Hep3B cells induced by BNIPL-1.

Acta Biochim Biophys Sin (Shanghai) 2005 Sep;37(9):618-24

Shanghai Medical College, Fudan University, Shanghai 200032, China.

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http://dx.doi.org/10.1111/j.1745-7270.2005.00086.xDOI Listing
September 2005

[Chromosome localization and genomic organization of five novel human genes related to cell growth control].

Yi Chuan 2002 Mar;24(2):111-6

National Laboratory for Oncogenes and Related Genes, Shanghai Cancer Institute, Shanghai 200032,China.

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March 2002

[Down-regulation of CT120A by RNA interference suppresses lung cancer cells growth].

Zhonghua Yi Xue Za Zhi 2005 Jun;85(23):1601-4

National Laboratory for Oncogenes and Related Genes, Shanghai Cancer Institute, Shanghai 200032, China.

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June 2005

P5644 interacts with phosphatidylinositol-4-phosphate adaptor protein-1 associated protein-1.

Mol Cell Biochem 2005 Mar;271(1-2):151-8

State Key Laboratory of Genetic Engineering, Institute of Genetic, School of Life Sciences, Fudan University, Shanghai 200433, PR China.

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http://dx.doi.org/10.1007/s11010-005-5907-6DOI Listing
March 2005

[Reconsideration of cancer as a systems disease concept].

Zhonghua Yi Xue Za Zhi 2005 Mar;85(8):505-7

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March 2005

[Experimental study of dually targeting gene therapy system for pituitary adenomas].

Zhonghua Yi Xue Za Zhi 2005 Jan;85(4):262-6

Department of Neurosurgery, General Hospital of Nanjing Command of People's Liberation Army, Nanjing 210002, China.

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January 2005

Altered gene expression profiles of NIH3T3 cells regulated by human lung cancer associated gene CT120.

Cell Res 2004 Dec;14(6):487-96

State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Shanghai Jiao-Tong University Medical School, Shanghai 200032, China.

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http://www.nature.com/articles/7290252
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http://dx.doi.org/10.1038/sj.cr.7290252DOI Listing
December 2004

[Down-regulation of CT120A by RNA interference suppresses lung cancer cells growth].

Zhonghua Yi Xue Za Zhi 2005 Jun;85(23):1601-4

National Laboratory for Oncogenes and Related Genes, Shanghai Cancer Institute, Shanghai 200032, China.

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June 2005

[A DNA vector-based RNAi technology to inhibit the activity of the telomerase of cell line HCCLM3].

Zhonghua Yi Xue Za Zhi 2004 Aug;84(16):1381-5

Institute of Life Science, Jiangsu University, Zhenjiang 212013, China.

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August 2004

[The effect of pro-angiogenic factors and their receptors on angiogenesis in hepatocellular carcinoma].

Zhonghua Zhong Liu Za Zhi 2004 Aug;26(8):472-5

Department of Hepatobiliary Surgery, the First Affiliated Hospital, College of Medical, Zhejiang University, Hangzhou 310003, China.

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August 2004

Differential gene expression in human hepatocellular carcinoma Hep3B cells induced by apoptosis-related gene BNIPL-2.

World J Gastroenterol 2004 May;10(9):1286-91

National Laboratory for Oncogenes and Related Genes, Shanghai Cancer Institute, Shanghai Jiaotong University, Shanghai 200032, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622767PMC
http://dx.doi.org/10.3748/wjg.v10.i9.1286DOI Listing
May 2004

[Study of GE7-transferring system mediated beta-galactosidase gene transfer in a rat model of ovarian tumor by intraarterial route].

Zhonghua Fu Chan Ke Za Zhi 2004 May;39(5):338-41

Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai 200011, China.

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May 2004

[Reporter genes transfer into human squamous cell carcinoma of larynx factor receptor mediated non-viral GE7 polypeptide delivery system with a new epidermal growth].

Zhonghua Er Bi Yan Hou Ke Za Zhi 2004 May;39(5):283-7

Department of Otorhinolaryngology-Head and Neck Surgery, First Hospital of Peiking University, Beijing 100034, China.

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May 2004

hNRAGE, a human neurotrophin receptor interacting MAGE homologue, regulates p53 transcriptional activity and inhibits cell proliferation.

FEBS Lett 2004 Apr;564(1-2):171-6

Jiangsu Key Laboratory for Molecular and Medical Biotechnology, Nanjing Normal University, Nanjing 210097, PR China.

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http://dx.doi.org/10.1016/S0014-5793(04)00353-9DOI Listing
April 2004

Differential expression of genes during aflatoxin B(1)-induced hepatocarcinogenesis in tree shrews.

World J Gastroenterol 2004 Feb;10(4):497-504

Department of Experimental Pathology, Guangxi Cancer Institute, Nanning 530021, Guangxi Zhuang Autonomous Region, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4716968PMC
http://dx.doi.org/10.3748/wjg.v10.i4.497DOI Listing
February 2004

[Differentially expressed genes in hepatocellular carcinoma of tree shrew induced by different factors].

Ai Zheng 2003 Oct;22(10):1018-22

Department of Experimental Pathology, Guangxi Cancer Institute,Nanning, Guangxi, 530021, PR China.

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October 2003

[Inhibition of proliferation in Jurkat cells transfected with exogenous HCAP1 gene].

Zhongguo Shi Yan Xue Ye Xue Za Zhi 2003 Oct;11(5):454-7

Institute of Hematology, Jinan University Medical College, Guangzhou 510632, China.

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October 2003

[In vitro experimental study of gene therapy for ovarian cancer with thymidine kinase gene of herpes simplex virus mediated by a non-viral GE7 delivery system].

Zhonghua Fu Chan Ke Za Zhi 2003 Oct;38(10):621-4

Department of Obstetrics and Gynecology, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China.

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October 2003

Construction of an EGF receptor-mediated histone H1(0)-based gene delivery system.

J Cancer Res Clin Oncol 2003 Aug 15;129(8):456-62. Epub 2003 Jul 15.

National Laboratory for Oncogenes and Related Genes, Shanghai Cancer Institute, 25/Ln 2200, Xie Tu Road, 200032, Shanghai, P.R. China.

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http://dx.doi.org/10.1007/s00432-003-0452-8DOI Listing
August 2003

Systemic genetic transfer of p21WAF-1 and GM-CSF utilizing of a novel oligopeptide-based EGF receptor targeting polyplex.

Cancer Gene Ther 2003 Jul;10(7):529-39

National Laboratory for Oncogenes and Related Genes, Shanghai Cancer Institute, Shanghai, China.

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http://dx.doi.org/10.1038/sj.cgt.7700596DOI Listing
July 2003

[Exogenous expression of SOCS box-deficient mutant ASB-8 suppresses the growth of lung adenocarcinoma SPC-A1 cells].

Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai) 2003 Jun;35(6):548-53

State Key Laboratory of Oncogenes and Related Genes, Shanghai Jiao Tong University Cancer Institute, Shanghai 200032, China.

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June 2003

Cloning and characterization of human IC53-2, a novel CDK5 activator binding protein.

Cell Res 2003 Apr;13(2):83-91

State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Shanghai 200032, China.

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http://dx.doi.org/10.1038/sj.cr.7290153DOI Listing
April 2003

[Expression of human novel gene CT120 in lung cancer and its effects on cell growth].

Ai Zheng 2003 Feb;22(2):113-8

State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Shanghai, 200032, PR China.

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February 2003

The promoter analysis of the human C17orf25 gene, a novel chromosome 17p13.3 gene.

Cell Res 2002 Dec;12(5-6):339-52

The State-Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Ln 2200/25, Xie-Tu Road, Shanghai 200032, China.

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http://dx.doi.org/10.1038/sj.cr.7290136DOI Listing
December 2002

[Expression of histone-based fusion protein HNHG in E.coli].

Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai) 2002 Nov;34(6):800-3

State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Shanghai 200032, China.

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November 2002

[Effects of two haplotypes of HCAP1 gene on cellular gene expression levels in a human hepatocarcinoma cell line Hep3B].

Ai Zheng 2002 Nov;21(11):1173-81

National Laboratory for Oncogenes and Related Genes, Shanghai Cancer Institute, Shanghai 200032, P. R. China.

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November 2002

The ATF/CREB site is the key element for transcription of the human RNA methyltransferase like 1(RNMTL1) gene, a newly discovered 17p13.3 gene.

Cell Res 2002 Sep;12(3-4):177-97

The State-key Laboratory for Oncogenes and Related Genes, Shanghai Cancer Institute, Xie-tu China.

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http://dx.doi.org/10.1038/sj.cr.7290124DOI Listing
September 2002

[Chromosome localization and genomic organization of five novel human genes related to cell growth control].

Yi Chuan 2002 Mar;24(2):111-6

National Laboratory for Oncogenes and Related Genes, Shanghai Cancer Institute, Shanghai 200032,China.

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March 2002

Modification of YACs by Homologous Recombination and Transfer of a 330 kb YAC into Mammalian Cells.

Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai) 1999 ;31(3):317-319

National Laboratory of Oncogenes and Related Genes, Shanghai Institute of Cancer, Shanghai 200032, China.

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January 1999